CN1086706C - 吡啶并[3,2,1－i,j][3,1]苯并噁嗪衍生物 - Google Patents

吡啶并[3,2,1－i,j][3,1]苯并噁嗪衍生物 Download PDF

Info

Publication number
CN1086706C
CN1086706C CN95194072A CN95194072A CN1086706C CN 1086706 C CN1086706 C CN 1086706C CN 95194072 A CN95194072 A CN 95194072A CN 95194072 A CN95194072 A CN 95194072A CN 1086706 C CN1086706 C CN 1086706C
Authority
CN
China
Prior art keywords
methyl
represents hydrogen
represent hydrogen
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN95194072A
Other languages
English (en)
Chinese (zh)
Other versions
CN1152921A (zh
Inventor
W·哈伦巴赫
T·希姆莱
T·耶特施赫
B·米尔克
K·D·布雷姆
R·恩德曼
F·皮罗
M·施特格曼
H·G·韦斯坦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1152921A publication Critical patent/CN1152921A/zh
Application granted granted Critical
Publication of CN1086706C publication Critical patent/CN1086706C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Seasonings (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Paper (AREA)
CN95194072A 1994-07-11 1995-06-28 吡啶并[3,2,1－i,j][3,1]苯并噁嗪衍生物 Expired - Fee Related CN1086706C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4424369.3 1994-07-11
DE4424369A DE4424369A1 (de) 1994-07-11 1994-07-11 Pyrido[3,2,1.i,j][3,1]benzoxazinderivate

Publications (2)

Publication Number Publication Date
CN1152921A CN1152921A (zh) 1997-06-25
CN1086706C true CN1086706C (zh) 2002-06-26

Family

ID=6522819

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95194072A Expired - Fee Related CN1086706C (zh) 1994-07-11 1995-06-28 吡啶并[3,2,1－i,j][3,1]苯并噁嗪衍生物

Country Status (24)

Country Link
US (1) US5854241A (enExample)
EP (1) EP0770083B1 (enExample)
JP (1) JPH10502377A (enExample)
KR (1) KR100372978B1 (enExample)
CN (1) CN1086706C (enExample)
AT (1) ATE195941T1 (enExample)
AU (1) AU684651B2 (enExample)
BR (1) BR9508384A (enExample)
CA (1) CA2194694A1 (enExample)
CZ (1) CZ5697A3 (enExample)
DE (2) DE4424369A1 (enExample)
DK (1) DK0770083T3 (enExample)
ES (1) ES2150576T3 (enExample)
FI (1) FI970092A7 (enExample)
HU (1) HUT77138A (enExample)
IL (1) IL114499A0 (enExample)
MX (1) MX9700306A (enExample)
NO (1) NO970079L (enExample)
NZ (1) NZ289419A (enExample)
PL (1) PL318097A1 (enExample)
SK (1) SK2797A3 (enExample)
TW (1) TW319766B (enExample)
WO (1) WO1996001829A1 (enExample)
ZA (1) ZA955707B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
CN1332962C (zh) * 2005-07-12 2007-08-22 武汉人福药业有限责任公司 一种合成甲磺酸帕珠沙星中间体的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4382892A (en) * 1980-09-02 1983-05-10 Daiichi Seiyaku Co., Ltd. Benzoxazine derivatives
JPH02157282A (ja) * 1988-12-12 1990-06-18 Wakunaga Pharmaceut Co Ltd 新規ピリドベンゾオキサジン誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3055894A (en) * 1960-03-09 1962-09-25 Pfizer & Co C New heterocyclic amides
US3551565A (en) * 1968-04-26 1970-12-29 Geigy Chem Corp Pharmaceutical compositions and uses of oxazinoisoquinoline derivatives
US3966743A (en) * 1968-07-23 1976-06-29 Boehringer Mannheim G.M.B.H. Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives
US3984548A (en) * 1974-02-11 1976-10-05 Riker Laboratories, Inc. Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides
US3883522A (en) * 1974-02-11 1975-05-13 Riker Laboratories Inc Substituted pyrido(1,2,3-de)-1,4-benzoxazines
FR2593810B1 (fr) * 1986-01-24 1988-04-22 Sanofi Sa Derives de la quinoleine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant
GB2236751B (en) * 1989-10-14 1993-04-28 Wyeth John & Brother Ltd Heterocyclic compounds
TW222276B (enExample) * 1992-01-27 1994-04-11 Fujisawa Pharmaceutical Co

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4382892A (en) * 1980-09-02 1983-05-10 Daiichi Seiyaku Co., Ltd. Benzoxazine derivatives
JPH02157282A (ja) * 1988-12-12 1990-06-18 Wakunaga Pharmaceut Co Ltd 新規ピリドベンゾオキサジン誘導体

Also Published As

Publication number Publication date
SK2797A3 (en) 1997-07-09
DE59508689D1 (de) 2000-10-05
FI970092A0 (fi) 1997-01-09
JPH10502377A (ja) 1998-03-03
HUT77138A (hu) 1998-03-02
ZA955707B (en) 1996-02-21
TW319766B (enExample) 1997-11-11
IL114499A0 (en) 1995-11-27
FI970092A7 (fi) 1997-01-09
NO970079D0 (no) 1997-01-09
CN1152921A (zh) 1997-06-25
EP0770083A1 (de) 1997-05-02
CA2194694A1 (en) 1996-01-25
KR100372978B1 (ko) 2003-06-12
NO970079L (no) 1997-01-09
CZ5697A3 (en) 1997-05-14
AU2925695A (en) 1996-02-09
EP0770083B1 (de) 2000-08-30
ATE195941T1 (de) 2000-09-15
PL318097A1 (en) 1997-05-12
NZ289419A (en) 1998-09-24
DE4424369A1 (de) 1996-01-18
ES2150576T3 (es) 2000-12-01
HU9700075D0 (en) 1997-02-28
MX9700306A (es) 1997-05-31
WO1996001829A1 (de) 1996-01-25
AU684651B2 (en) 1997-12-18
BR9508384A (pt) 1997-12-23
US5854241A (en) 1998-12-29
DK0770083T3 (da) 2000-10-16

Similar Documents

Publication Publication Date Title
CN1189469C (zh) 作为抗菌剂的3－(杂芳基乙酰氨基)－2－氧化－氮杂环丁烷－1－磺酸衍生物
CN1151151C (zh) 8-甲氧基-喹诺酮羧酸类的制备方法
CN88102247A (zh) 新颖的吡唑并[3，4-d]嘧啶、其制备方法及其药物组合物
CN1108658A (zh) 雪花胺衍生物及其制备方法和其作为药剂的用途
CN87107149A (zh) 7-[(间位取代的)苯基甘氨酸]1-碳代-1-去硫头孢菌素
CN1086706C (zh) 吡啶并[3,2,1－i,j][3,1]苯并噁嗪衍生物
CN1052864A (zh) 喹诺酮化合物及其制备方法
CN1259952A (zh) 喹诺酮羧酸衍生物
CN86104256A (zh) 1，8-桥连 4-喹诺酮-3-羧酸类的制备方法
CN1041731C (zh) 吡啶并[1,2,3—d,e][1,3,4]苯并噁二嗪衍生物
CN1227252C (zh) 制备6－甲基－2－(4－甲基－苯基)－咪唑并[1,2－a]吡啶－3－(N,N－二甲基－乙酰胺)和中间体的方法
CN1253458C (zh) 物质gm－95的制备方法
HK1042704A1 (en) Semi-hydrochloride of 8-cyan-1-cyclopropyl -7-(1s,6s-2,8-diazabicyclo [4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro -4-oxo-3- quinoline carboxylic acid
US8703939B2 (en) Method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives
CN1106412A (zh) 1-(2-氟环丙基)喹诺酮甲酸和1-(2-氟环丙基)二氮杂萘酮甲酸的衍生物
CN1156994A (zh) 新噻唑[3，2-a]喹啉衍生物和噻唑[3，2-a]萘啶衍生物
CN1090185C (zh) 有双环氨基取代的吡啶酮羧酸衍生物,其酯及盐,以及可用作其中间体的双环类胺
HK1080076A1 (zh) 喹诺酮羧酸衍生物的制备方法
CN1194977C (zh) 四环氟喹诺酮羧酸，其制备方法及其为活性成份的药物组合物
CN1055473C (zh) 1,9－桥连的噻唑并[3,2－a]喹啉衍生物
CN1188417C (zh) 作为抗菌剂的3,6－二取代青霉砜衍生物
CN1778800A (zh) 手性哌嗪取代的喹诺酮羧酸衍生物及其制备方法和用途
CN87102870A (zh) 2-甲基-3-脲基-喹喔啉-1，4-二-n-氧化物的制备方法
CN1606558A (zh) 新型头孢菌素化合物及其制备方法
EP2161269A1 (en) Process for the preparation of amorphous gemifloxacin

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee