MX9700306A - Derivados de pirido[3,2,1-i-j][3,1]benzoxazina. - Google Patents
Derivados de pirido[3,2,1-i-j][3,1]benzoxazina.Info
- Publication number
- MX9700306A MX9700306A MX9700306A MX9700306A MX9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrogen
- methyl
- hydroxy
- alkyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Paper (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Seasonings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invencion se refiere a nuevos derivados de pirido[3,2,1-i-j][3,1]benzoxazina, de la formula general (I), en la que R1 significa hidrogeno o alquilo con 1 a 4 átomos de carbono, substituido en caso dado por hidroxi o halogeno, R2 independientemente de R1 significa hidrogeno o metilo, R3 significa hidrogeno o alquilo con 1 a 4 átomos de carbono, R3' independientemente de R3 significa hidrogeno o metilo, R4 significa hidrogeno, alquilo con 1 a 4 átomos de carbono, substituido en caso dado por hidroxi, metoxi, amino, metilamino o dimetilamino o significa (5-metil-2-oxo-1,3-dioxol-4-il)-metilo, X1 significa hidrogeno o halogeno, Z significa restos de las estructuras, donde R7 significa hidrogeno, hidroxi, -NR10R11, hidroximetilo, -CH2-HR10R11, carboxilo, metoxicarbonilo o etoxicarbonilo, donde, R10 significa hidrogeno, alquilo con 1 a 3 átomos de carbono substituido en caso dado por hidroxi, alcoxicarbonilo con 1 a 4 átomos de carbono en la parte alcoxi o acilo con 1 a 3 átomos de carbono, R11 significa hidrogeno o metilo, R8 significa hidrogeno, alquilo con 1 a 3 átomos de carbono de cadena lineal o de cadena ramificada o ciclopropilo, R9 significa hidrogeno o metilo, R6 significa hidrogeno o metilo, R5 significa hidrogeno, metilo o significa restos con las estructuras -CH=CH-COOR5', -CH2-CH2-COOR5', -CH-CO-CH3, -CH2-CH2-CN, R5 significa metilo o etilo, B significa -CH2-, O o un enlace directo, a su obtencion y a su empleo para la terapia o la profilaxis de infecciones bacterianas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4424369A DE4424369A1 (de) | 1994-07-11 | 1994-07-11 | Pyrido[3,2,1.i,j][3,1]benzoxazinderivate |
PCT/EP1995/002510 WO1996001829A1 (de) | 1994-07-11 | 1995-06-28 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINDERIVATE |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9700306A true MX9700306A (es) | 1997-05-31 |
Family
ID=6522819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9700306A MX9700306A (es) | 1994-07-11 | 1995-06-28 | Derivados de pirido[3,2,1-i-j][3,1]benzoxazina. |
Country Status (24)
Country | Link |
---|---|
US (1) | US5854241A (es) |
EP (1) | EP0770083B1 (es) |
JP (1) | JPH10502377A (es) |
KR (1) | KR100372978B1 (es) |
CN (1) | CN1086706C (es) |
AT (1) | ATE195941T1 (es) |
AU (1) | AU684651B2 (es) |
BR (1) | BR9508384A (es) |
CA (1) | CA2194694A1 (es) |
CZ (1) | CZ5697A3 (es) |
DE (2) | DE4424369A1 (es) |
DK (1) | DK0770083T3 (es) |
ES (1) | ES2150576T3 (es) |
FI (1) | FI970092A0 (es) |
HU (1) | HUT77138A (es) |
IL (1) | IL114499A0 (es) |
MX (1) | MX9700306A (es) |
NO (1) | NO970079L (es) |
NZ (1) | NZ289419A (es) |
PL (1) | PL318097A1 (es) |
SK (1) | SK2797A3 (es) |
TW (1) | TW319766B (es) |
WO (1) | WO1996001829A1 (es) |
ZA (1) | ZA955707B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
AR020661A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento |
US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
CN1332962C (zh) * | 2005-07-12 | 2007-08-22 | 武汉人福药业有限责任公司 | 一种合成甲磺酸帕珠沙星中间体的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3055894A (en) * | 1960-03-09 | 1962-09-25 | Pfizer & Co C | New heterocyclic amides |
US3551565A (en) * | 1968-04-26 | 1970-12-29 | Geigy Chem Corp | Pharmaceutical compositions and uses of oxazinoisoquinoline derivatives |
US3966743A (en) * | 1968-07-23 | 1976-06-29 | Boehringer Mannheim G.M.B.H. | Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives |
US3984548A (en) * | 1974-02-11 | 1976-10-05 | Riker Laboratories, Inc. | Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides |
US3883522A (en) * | 1974-02-11 | 1975-05-13 | Riker Laboratories Inc | Substituted pyrido(1,2,3-de)-1,4-benzoxazines |
JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
FR2593810B1 (fr) * | 1986-01-24 | 1988-04-22 | Sanofi Sa | Derives de la quinoleine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
JPH02157282A (ja) * | 1988-12-12 | 1990-06-18 | Wakunaga Pharmaceut Co Ltd | 新規ピリドベンゾオキサジン誘導体 |
GB2236751B (en) * | 1989-10-14 | 1993-04-28 | Wyeth John & Brother Ltd | Heterocyclic compounds |
TW222276B (es) * | 1992-01-27 | 1994-04-11 | Fujisawa Pharmaceutical Co |
-
1994
- 1994-07-11 DE DE4424369A patent/DE4424369A1/de not_active Withdrawn
-
1995
- 1995-06-28 HU HU9700075A patent/HUT77138A/hu unknown
- 1995-06-28 US US08/765,212 patent/US5854241A/en not_active Expired - Fee Related
- 1995-06-28 DE DE59508689T patent/DE59508689D1/de not_active Expired - Fee Related
- 1995-06-28 ES ES95924949T patent/ES2150576T3/es not_active Expired - Lifetime
- 1995-06-28 WO PCT/EP1995/002510 patent/WO1996001829A1/de active IP Right Grant
- 1995-06-28 CN CN95194072A patent/CN1086706C/zh not_active Expired - Fee Related
- 1995-06-28 SK SK27-97A patent/SK2797A3/sk unknown
- 1995-06-28 BR BR9508384A patent/BR9508384A/pt not_active IP Right Cessation
- 1995-06-28 EP EP95924949A patent/EP0770083B1/de not_active Expired - Lifetime
- 1995-06-28 MX MX9700306A patent/MX9700306A/es unknown
- 1995-06-28 CZ CZ9756A patent/CZ5697A3/cs unknown
- 1995-06-28 DK DK95924949T patent/DK0770083T3/da active
- 1995-06-28 AU AU29256/95A patent/AU684651B2/en not_active Ceased
- 1995-06-28 NZ NZ289419A patent/NZ289419A/en unknown
- 1995-06-28 CA CA002194694A patent/CA2194694A1/en not_active Abandoned
- 1995-06-28 JP JP8504083A patent/JPH10502377A/ja active Pending
- 1995-06-28 KR KR1019970700058A patent/KR100372978B1/ko not_active IP Right Cessation
- 1995-06-28 PL PL95318097A patent/PL318097A1/xx unknown
- 1995-06-28 AT AT95924949T patent/ATE195941T1/de not_active IP Right Cessation
- 1995-06-30 TW TW084106729A patent/TW319766B/zh active
- 1995-07-07 IL IL11449995A patent/IL114499A0/xx unknown
- 1995-07-10 ZA ZA955707A patent/ZA955707B/xx unknown
-
1997
- 1997-01-09 FI FI970092A patent/FI970092A0/fi unknown
- 1997-01-09 NO NO970079A patent/NO970079L/no unknown
Also Published As
Publication number | Publication date |
---|---|
HU9700075D0 (en) | 1997-02-28 |
AU2925695A (en) | 1996-02-09 |
WO1996001829A1 (de) | 1996-01-25 |
NZ289419A (en) | 1998-09-24 |
US5854241A (en) | 1998-12-29 |
NO970079D0 (no) | 1997-01-09 |
EP0770083B1 (de) | 2000-08-30 |
SK2797A3 (en) | 1997-07-09 |
AU684651B2 (en) | 1997-12-18 |
JPH10502377A (ja) | 1998-03-03 |
CN1086706C (zh) | 2002-06-26 |
PL318097A1 (en) | 1997-05-12 |
NO970079L (no) | 1997-01-09 |
BR9508384A (pt) | 1997-12-23 |
CZ5697A3 (en) | 1997-05-14 |
ATE195941T1 (de) | 2000-09-15 |
DE4424369A1 (de) | 1996-01-18 |
DE59508689D1 (de) | 2000-10-05 |
CA2194694A1 (en) | 1996-01-25 |
CN1152921A (zh) | 1997-06-25 |
ZA955707B (en) | 1996-02-21 |
DK0770083T3 (da) | 2000-10-16 |
TW319766B (es) | 1997-11-11 |
ES2150576T3 (es) | 2000-12-01 |
IL114499A0 (en) | 1995-11-27 |
HUT77138A (hu) | 1998-03-02 |
EP0770083A1 (de) | 1997-05-02 |
FI970092A (fi) | 1997-01-09 |
KR100372978B1 (ko) | 2003-06-12 |
FI970092A0 (fi) | 1997-01-09 |
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