MX9700306A - Derivados de pirido[3,2,1-i-j][3,1]benzoxazina. - Google Patents
Derivados de pirido[3,2,1-i-j][3,1]benzoxazina.Info
- Publication number
- MX9700306A MX9700306A MX9700306A MX9700306A MX9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A MX 9700306 A MX9700306 A MX 9700306A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrogen
- methyl
- hydroxy
- alkyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Paper (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Seasonings (AREA)
Abstract
La presente invencion se refiere a nuevos derivados de pirido[3,2,1-i-j][3,1]benzoxazina, de la formula general (I), en la que R1 significa hidrogeno o alquilo con 1 a 4 átomos de carbono, substituido en caso dado por hidroxi o halogeno, R2 independientemente de R1 significa hidrogeno o metilo, R3 significa hidrogeno o alquilo con 1 a 4 átomos de carbono, R3' independientemente de R3 significa hidrogeno o metilo, R4 significa hidrogeno, alquilo con 1 a 4 átomos de carbono, substituido en caso dado por hidroxi, metoxi, amino, metilamino o dimetilamino o significa (5-metil-2-oxo-1,3-dioxol-4-il)-metilo, X1 significa hidrogeno o halogeno, Z significa restos de las estructuras, donde R7 significa hidrogeno, hidroxi, -NR10R11, hidroximetilo, -CH2-HR10R11, carboxilo, metoxicarbonilo o etoxicarbonilo, donde, R10 significa hidrogeno, alquilo con 1 a 3 átomos de carbono substituido en caso dado por hidroxi, alcoxicarbonilo con 1 a 4 átomos de carbono en la parte alcoxi o acilo con 1 a 3 átomos de carbono, R11 significa hidrogeno o metilo, R8 significa hidrogeno, alquilo con 1 a 3 átomos de carbono de cadena lineal o de cadena ramificada o ciclopropilo, R9 significa hidrogeno o metilo, R6 significa hidrogeno o metilo, R5 significa hidrogeno, metilo o significa restos con las estructuras -CH=CH-COOR5', -CH2-CH2-COOR5', -CH-CO-CH3, -CH2-CH2-CN, R5 significa metilo o etilo, B significa -CH2-, O o un enlace directo, a su obtencion y a su empleo para la terapia o la profilaxis de infecciones bacterianas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4424369A DE4424369A1 (de) | 1994-07-11 | 1994-07-11 | Pyrido[3,2,1.i,j][3,1]benzoxazinderivate |
| PCT/EP1995/002510 WO1996001829A1 (de) | 1994-07-11 | 1995-06-28 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINDERIVATE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9700306A true MX9700306A (es) | 1997-05-31 |
Family
ID=6522819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9700306A MX9700306A (es) | 1994-07-11 | 1995-06-28 | Derivados de pirido[3,2,1-i-j][3,1]benzoxazina. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5854241A (es) |
| EP (1) | EP0770083B1 (es) |
| JP (1) | JPH10502377A (es) |
| KR (1) | KR100372978B1 (es) |
| CN (1) | CN1086706C (es) |
| AT (1) | ATE195941T1 (es) |
| AU (1) | AU684651B2 (es) |
| BR (1) | BR9508384A (es) |
| CA (1) | CA2194694A1 (es) |
| CZ (1) | CZ5697A3 (es) |
| DE (2) | DE4424369A1 (es) |
| DK (1) | DK0770083T3 (es) |
| ES (1) | ES2150576T3 (es) |
| FI (1) | FI970092A (es) |
| HU (1) | HUT77138A (es) |
| IL (1) | IL114499A0 (es) |
| MX (1) | MX9700306A (es) |
| NO (1) | NO970079D0 (es) |
| NZ (1) | NZ289419A (es) |
| PL (1) | PL318097A1 (es) |
| SK (1) | SK2797A3 (es) |
| TW (1) | TW319766B (es) |
| WO (1) | WO1996001829A1 (es) |
| ZA (1) | ZA955707B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| AR020661A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento |
| US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
| US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
| CN1332962C (zh) * | 2005-07-12 | 2007-08-22 | 武汉人福药业有限责任公司 | 一种合成甲磺酸帕珠沙星中间体的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3055894A (en) * | 1960-03-09 | 1962-09-25 | Pfizer & Co C | New heterocyclic amides |
| US3551565A (en) * | 1968-04-26 | 1970-12-29 | Geigy Chem Corp | Pharmaceutical compositions and uses of oxazinoisoquinoline derivatives |
| US3966743A (en) * | 1968-07-23 | 1976-06-29 | Boehringer Mannheim G.M.B.H. | Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives |
| US3883522A (en) * | 1974-02-11 | 1975-05-13 | Riker Laboratories Inc | Substituted pyrido(1,2,3-de)-1,4-benzoxazines |
| US3984548A (en) * | 1974-02-11 | 1976-10-05 | Riker Laboratories, Inc. | Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides |
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| FR2593810B1 (fr) * | 1986-01-24 | 1988-04-22 | Sanofi Sa | Derives de la quinoleine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
| JPH02157282A (ja) * | 1988-12-12 | 1990-06-18 | Wakunaga Pharmaceut Co Ltd | 新規ピリドベンゾオキサジン誘導体 |
| GB2236751B (en) * | 1989-10-14 | 1993-04-28 | Wyeth John & Brother Ltd | Heterocyclic compounds |
| TW222276B (es) * | 1992-01-27 | 1994-04-11 | Fujisawa Pharmaceutical Co |
-
1994
- 1994-07-11 DE DE4424369A patent/DE4424369A1/de not_active Withdrawn
-
1995
- 1995-06-28 CZ CZ9756A patent/CZ5697A3/cs unknown
- 1995-06-28 US US08/765,212 patent/US5854241A/en not_active Expired - Fee Related
- 1995-06-28 NZ NZ289419A patent/NZ289419A/en unknown
- 1995-06-28 AT AT95924949T patent/ATE195941T1/de not_active IP Right Cessation
- 1995-06-28 CN CN95194072A patent/CN1086706C/zh not_active Expired - Fee Related
- 1995-06-28 DK DK95924949T patent/DK0770083T3/da active
- 1995-06-28 ES ES95924949T patent/ES2150576T3/es not_active Expired - Lifetime
- 1995-06-28 PL PL95318097A patent/PL318097A1/xx unknown
- 1995-06-28 DE DE59508689T patent/DE59508689D1/de not_active Expired - Fee Related
- 1995-06-28 JP JP8504083A patent/JPH10502377A/ja active Pending
- 1995-06-28 SK SK27-97A patent/SK2797A3/sk unknown
- 1995-06-28 CA CA002194694A patent/CA2194694A1/en not_active Abandoned
- 1995-06-28 KR KR1019970700058A patent/KR100372978B1/ko not_active IP Right Cessation
- 1995-06-28 WO PCT/EP1995/002510 patent/WO1996001829A1/de active IP Right Grant
- 1995-06-28 BR BR9508384A patent/BR9508384A/pt not_active IP Right Cessation
- 1995-06-28 EP EP95924949A patent/EP0770083B1/de not_active Expired - Lifetime
- 1995-06-28 HU HU9700075A patent/HUT77138A/hu unknown
- 1995-06-28 MX MX9700306A patent/MX9700306A/es unknown
- 1995-06-28 AU AU29256/95A patent/AU684651B2/en not_active Ceased
- 1995-06-30 TW TW084106729A patent/TW319766B/zh active
- 1995-07-07 IL IL11449995A patent/IL114499A0/xx unknown
- 1995-07-10 ZA ZA955707A patent/ZA955707B/xx unknown
-
1997
- 1997-01-09 FI FI970092A patent/FI970092A/fi unknown
- 1997-01-09 NO NO970079A patent/NO970079D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1152921A (zh) | 1997-06-25 |
| AU684651B2 (en) | 1997-12-18 |
| US5854241A (en) | 1998-12-29 |
| DE59508689D1 (de) | 2000-10-05 |
| CZ5697A3 (en) | 1997-05-14 |
| DK0770083T3 (da) | 2000-10-16 |
| WO1996001829A1 (de) | 1996-01-25 |
| NO970079L (no) | 1997-01-09 |
| KR100372978B1 (ko) | 2003-06-12 |
| FI970092A0 (fi) | 1997-01-09 |
| EP0770083A1 (de) | 1997-05-02 |
| HU9700075D0 (en) | 1997-02-28 |
| ES2150576T3 (es) | 2000-12-01 |
| JPH10502377A (ja) | 1998-03-03 |
| HUT77138A (hu) | 1998-03-02 |
| TW319766B (es) | 1997-11-11 |
| NO970079D0 (no) | 1997-01-09 |
| DE4424369A1 (de) | 1996-01-18 |
| SK2797A3 (en) | 1997-07-09 |
| CA2194694A1 (en) | 1996-01-25 |
| CN1086706C (zh) | 2002-06-26 |
| FI970092A (fi) | 1997-01-09 |
| EP0770083B1 (de) | 2000-08-30 |
| BR9508384A (pt) | 1997-12-23 |
| AU2925695A (en) | 1996-02-09 |
| ZA955707B (en) | 1996-02-21 |
| IL114499A0 (en) | 1995-11-27 |
| ATE195941T1 (de) | 2000-09-15 |
| PL318097A1 (en) | 1997-05-12 |
| NZ289419A (en) | 1998-09-24 |
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