CN1086658A - Antiseptic preserving liquid for dead body specimen - Google Patents
Antiseptic preserving liquid for dead body specimen Download PDFInfo
- Publication number
- CN1086658A CN1086658A CN 93111665 CN93111665A CN1086658A CN 1086658 A CN1086658 A CN 1086658A CN 93111665 CN93111665 CN 93111665 CN 93111665 A CN93111665 A CN 93111665A CN 1086658 A CN1086658 A CN 1086658A
- Authority
- CN
- China
- Prior art keywords
- benzoate
- liquid
- preservation
- glycerine
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 18
- 230000002421 anti-septic effect Effects 0.000 title claims abstract description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 23
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000004321 preservation Methods 0.000 claims abstract description 16
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000011187 glycerol Nutrition 0.000 claims abstract description 9
- 235000010333 potassium nitrate Nutrition 0.000 claims abstract description 8
- 239000004323 potassium nitrate Substances 0.000 claims abstract description 8
- 235000019441 ethanol Nutrition 0.000 claims abstract description 3
- 229940050390 benzoate Drugs 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 5
- 239000012530 fluid Substances 0.000 claims description 5
- 239000011734 sodium Substances 0.000 claims description 5
- 229910052708 sodium Inorganic materials 0.000 claims description 5
- 235000010237 calcium benzoate Nutrition 0.000 claims description 2
- 239000004301 calcium benzoate Substances 0.000 claims description 2
- HZQXCUSDXIKLGS-UHFFFAOYSA-L calcium;dibenzoate;trihydrate Chemical compound O.O.O.[Ca+2].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C1=CC=CC=C1 HZQXCUSDXIKLGS-UHFFFAOYSA-L 0.000 claims description 2
- PJJZFXPJNUVBMR-UHFFFAOYSA-L magnesium benzoate Chemical compound [Mg+2].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C1=CC=CC=C1 PJJZFXPJNUVBMR-UHFFFAOYSA-L 0.000 claims description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 2
- 235000010235 potassium benzoate Nutrition 0.000 claims description 2
- 239000004300 potassium benzoate Substances 0.000 claims description 2
- 229940103091 potassium benzoate Drugs 0.000 claims description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 2
- 235000010234 sodium benzoate Nutrition 0.000 claims description 2
- 239000004299 sodium benzoate Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 9
- 230000000149 penetrating effect Effects 0.000 abstract description 5
- 210000003484 anatomy Anatomy 0.000 abstract description 3
- 230000000855 fungicidal effect Effects 0.000 abstract description 3
- 231100000252 nontoxic Toxicity 0.000 abstract description 3
- 230000003000 nontoxic effect Effects 0.000 abstract description 3
- 238000001556 precipitation Methods 0.000 abstract description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical class O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 5
- 238000005260 corrosion Methods 0.000 description 4
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000005844 Thymol Substances 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229960000790 thymol Drugs 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 201000008197 Laryngitis Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 150000004054 benzoquinones Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 235000019256 formaldehyde Nutrition 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- MCXBMLBTPQEQJP-UHFFFAOYSA-N potassium;sodium;dinitrate Chemical compound [Na+].[K+].[O-][N+]([O-])=O.[O-][N+]([O-])=O MCXBMLBTPQEQJP-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to medical anatomy, the preservation liquid of cadaver sample after anticorrosion fixedly processing particularly, it is formulated by benzoate, potassium nitrate, ethanol, glycerine that its component of liquid is preserved in embalming.Its preservation effect is good, and is reliable to the anticorrosion fungicidal properties of cadaver sample, sample does not go mouldy, does not shrink, the color nature, organize pliable and tough, moistening.This preservation liquid is nontoxic, do not have bad penetrating odor, do not have precipitation, and staff's health is had no effect.It is a comparatively ideal antiseptic preserving liquid for dead body specimen in the present teaching and scientific research.
Description
The invention belongs to medical anatomy, particularly antiseptic preserving liquid for dead body specimen.
The human or animal after death, tissue automatic soup-dissolving if without anticorrosion fixing and preserve, can take place in corpse very soon, corruption is disintegrated gradually.Scientifically be familiar with organization of human body, be unable to do without Autopsied practice, for anatomical teaching and scientific research, the effective anticorrosion preservation of inevitable requirement corpse.Bad variations such as the corpse process is anticorrosion fixedly to be after anticorrosion perfusion is handled, appropriate preservation measure to be arranged also, and it is stiff to avoid water evaporates, generation to dry up, and the surface is mildew and rot.Common preservation method: 1, the wet preservation, 2, oil preserves, 3, do and preserve, 4, cold preservation.Wherein wet preservation method is with the most use.Because its device simple, cost is lower, and is respond well.Its method often is immersed in corpse and fills the corpse groove of preserving liquid, in corpse case or the corpse pond." the anatomy technology " the 22nd page that in November, 1985, people's health was published, preserve liquid and adopt following several usually:
1, formaldehydes solution: typical concentrations is 5% formalin solution, and preservation effect is fine.Be that a kind of traditional good sample is preserved liquid, continue to use for a long time.Shortcoming is that penetrating odor is very strong, and voloxidation can take place, and variations such as polymerization precipitation, so that concentration decline for guaranteeing preservation effect, also need regularly be added this solution in storage life; Formalin solution is very big to operating personnel's digestion, respiratory tract influence, often causes diseases such as pharyngitis, laryngitis, conjunctivitis, also causes human body contact site dry skin, cracking.
2, phenols solution: typical concentrations 2-3%, favorable anti-corrosion effect, penetrating odor is little, but the peripheral termination of nerve is had detrimental effect.The phenol oxidation easily becomes benzoquinones, after time is permanent, yellowish-brown mud sediment thing is arranged in the corpse pond, can reduce antiseptic effect.
3, salt solution: 20% sodium chloride solution commonly used, the high dehydration of concentration is too strong, and the corpse tissue can shrink because of dehydration, gives to dissect to operate and brings certain difficulty.
4, bromogeramine solution: typical concentrations 0.1-0.2%, nonirritant, toxicity is low, and stronger sterilizing power is arranged.But reduce effect because of bromogeramine is subject to organic substance influence,, and should avoid using the aluminum apparatus many inorganic salts adapted taboos.
5, three comrade's developments such as the Hu Jianguang of Hunan Medical University's human dissection teaching and research room and " specimen anti-corrosion is preserved liquid No. 1 " of delivering the 24th page of in December, 1992 " science association is dissected in the Hunan Province " are formulated for raw material with benzoic acid, ethanol, glycerine, carbolic acid, potassium nitrate, thymol etc., and preservation effect is good.But owing to used the bigger carbolic acid of toxicity, it can make neuratorphy, and low concentration phenol still can make the nerve ending paralysis, and in addition, it is many that this preserves fluid component, adopted valuable thymol, the cost height.
The purpose of this invention is to provide and a kind ofly can overcome above-mentioned shortcoming, reliable to the specimen anti-corrosion fungicidal properties, safe in utilization nontoxic, there is not bad penetrating odor, do not damage the peripheral termination of nerve, harmless, liquid is preserved in the comparatively desirable embalming that cost is low.
Technical scheme of the present invention is such: it is the antiseptic preserving fluid that active ingredient is formed by benzoate, ethanol, potassium nitrate (sodium), glycerine that liquid is preserved in embalming.Configuration proportion is as follows:
Benzoate: 1-10 gram;
Ethanol (95%): 50-200 milliliter;
Potassium nitrate (sodium): 10-20 gram;
Glycerine: 5-100 milliliter;
Running water: add to 1000 milliliters.
Best proportioning adopts following ratio:
Benzoate: 3-8 gram;
Ethanol (95%): 100-200 milliliter;
Potassium nitrate (sodium): 5-20 gram;
Glycerine: 10-50 milliliter;
Running water: add to 1000 milliliters.
Above-mentioned benzoate can be Sodium Benzoate or Potassium Benzoate, and perhaps magnesium benzoate can also be a calcium benzoate.The characteristics of this preservation liquid are that component is few and nonhazardous has no irritating odor, and with low cost, preparing process is simple.Compound method is at first benzoate and potassium nitrate (sodium) to be dissolved in the running water commonly used, after treating CL, under condition of stirring, add ethanol and glycerine, promptly become antiseptic preserving liquid for dead body specimen of the present invention after stirring, through facts have proved: its preservation effect is good, reliable to the specimen anti-corrosion fungicidal properties, sample does not go mouldy, do not shrink, color nature, organize pliable and tough, moistening, promptly be during the broiling summer, sample is imparted knowledge to students continuously and is used a week also to be difficult for drying, has created condition for the desirable teaching and scientific research environment of form subject.This antiseptic preserving fluid is nontoxic, does not have bad penetrating odor, does not have precipitation, the solution clear, and volatility is low, and operating personnel's health is had no effect.This preservation liquid only is applicable to that the cadaver sample after anticorrosion fixedly processing preserves, and is antiseptic preserving liquid for dead body specimen desirable in the present teaching and scientific research through facts have proved.
Claims (2)
1, a kind of antiseptic preserving liquid for dead body specimen, this preservation fluid component of its feature are formulated by benzoate, ethanol, potassium nitrate, glycerine, and configuration proportion is as follows:
Benzoate: 1-10 gram;
Ethanol (95%): 50-200 milliliter;
Potassium nitrate (sodium): 10-20 gram;
Glycerine: 5-100 milliliter;
Running water: add to 1000 milliliters.
Best proportioning adopts following ratio:
Benzoate: 3-8 gram;
Ethanol (95%): 100-200 milliliter;
Potassium nitrate (sodium): 5-20 gram;
Glycerine: 10-50 milliliter;
Running water: add to 1000 milliliters.
2, antiseptic preserving fluid according to claim 1 is characterized in that benzoate can be Sodium Benzoate or Potassium Benzoate or magnesium benzoate, can also be calcium benzoate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93111665A CN1047061C (en) | 1993-08-19 | 1993-08-19 | Antiseptic preserving liquid for dead body specimen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93111665A CN1047061C (en) | 1993-08-19 | 1993-08-19 | Antiseptic preserving liquid for dead body specimen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1086658A true CN1086658A (en) | 1994-05-18 |
| CN1047061C CN1047061C (en) | 1999-12-08 |
Family
ID=4989429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93111665A Expired - Fee Related CN1047061C (en) | 1993-08-19 | 1993-08-19 | Antiseptic preserving liquid for dead body specimen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1047061C (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100448351C (en) * | 2007-07-12 | 2009-01-07 | 江苏省原子医学研究所 | A specimen antiseptic fixative |
| CN101984804A (en) * | 2010-11-03 | 2011-03-16 | 西安医学院 | Corpse preservation solution and preparation method thereof |
| CN101305710B (en) * | 2008-06-18 | 2011-06-22 | 陈庆明 | Corpus antiseptic and its preparation method |
| CN101473812B (en) * | 2009-01-24 | 2011-09-14 | 温州医学院 | Antiseptic fixing liquid composition for cadaver sample and preparation method thereof |
| CN102578073A (en) * | 2012-02-07 | 2012-07-18 | 王永红 | Preserving fluid for biological sample |
| CN104094923A (en) * | 2013-04-09 | 2014-10-15 | 民政部一零一研究所 | Preservative liquid for corpses, tissue and dissections, and application method thereof |
| CN105052891A (en) * | 2015-07-16 | 2015-11-18 | 内蒙古科技大学包头医学院 | Long-stem storage method for anatomical visceral specimen |
| CN105432661A (en) * | 2015-07-08 | 2016-03-30 | 清华大学 | Waste drosophila treatment liquid |
| CN105532637A (en) * | 2016-01-07 | 2016-05-04 | 别永信 | Human body teaching specimen preserving fluid and preparing method thereof |
| CN109452261A (en) * | 2018-12-27 | 2019-03-12 | 福建医科大学 | A kind of specimen preserving liquid and preparation method thereof |
| CN110604127A (en) * | 2018-06-14 | 2019-12-24 | 宁波化奇工程技术有限公司 | Non-formaldehyde environment-friendly biological specimen preserving fluid |
| CN113519505A (en) * | 2021-09-01 | 2021-10-22 | 宁波西敦医药包衣科技有限公司 | Environmental protection aqueous crosslinking agent biological tissue preservation material and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85105522A (en) * | 1985-07-17 | 1987-01-14 | 陈国发 | The making of dry-keeping macropathological specimens and preservation |
| CN1021538C (en) * | 1988-03-08 | 1993-07-14 | 王向前 | Proportioning method of colour protective and antiseptic agent for specimens of living beings |
-
1993
- 1993-08-19 CN CN93111665A patent/CN1047061C/en not_active Expired - Fee Related
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100448351C (en) * | 2007-07-12 | 2009-01-07 | 江苏省原子医学研究所 | A specimen antiseptic fixative |
| CN101305710B (en) * | 2008-06-18 | 2011-06-22 | 陈庆明 | Corpus antiseptic and its preparation method |
| CN101473812B (en) * | 2009-01-24 | 2011-09-14 | 温州医学院 | Antiseptic fixing liquid composition for cadaver sample and preparation method thereof |
| CN101984804A (en) * | 2010-11-03 | 2011-03-16 | 西安医学院 | Corpse preservation solution and preparation method thereof |
| CN102578073A (en) * | 2012-02-07 | 2012-07-18 | 王永红 | Preserving fluid for biological sample |
| CN104094923B (en) * | 2013-04-09 | 2016-06-15 | 民政部一零一研究所 | A kind of antiseptic preserving fluid for corpse, tissue and dissection and using method thereof |
| CN104094923A (en) * | 2013-04-09 | 2014-10-15 | 民政部一零一研究所 | Preservative liquid for corpses, tissue and dissections, and application method thereof |
| CN105432661A (en) * | 2015-07-08 | 2016-03-30 | 清华大学 | Waste drosophila treatment liquid |
| CN105052891A (en) * | 2015-07-16 | 2015-11-18 | 内蒙古科技大学包头医学院 | Long-stem storage method for anatomical visceral specimen |
| CN105052891B (en) * | 2015-07-16 | 2017-03-08 | 内蒙古科技大学包头医学院 | The long-term preservation method of anatomy internal organ sample |
| CN105532637A (en) * | 2016-01-07 | 2016-05-04 | 别永信 | Human body teaching specimen preserving fluid and preparing method thereof |
| CN110604127A (en) * | 2018-06-14 | 2019-12-24 | 宁波化奇工程技术有限公司 | Non-formaldehyde environment-friendly biological specimen preserving fluid |
| CN109452261A (en) * | 2018-12-27 | 2019-03-12 | 福建医科大学 | A kind of specimen preserving liquid and preparation method thereof |
| CN113519505A (en) * | 2021-09-01 | 2021-10-22 | 宁波西敦医药包衣科技有限公司 | Environmental protection aqueous crosslinking agent biological tissue preservation material and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1047061C (en) | 1999-12-08 |
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