CN1082051C - 新的环缩肽pf1022物质的衍生物 - Google Patents

新的环缩肽pf1022物质的衍生物 Download PDF

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Publication number
CN1082051C
CN1082051C CN96198101A CN96198101A CN1082051C CN 1082051 C CN1082051 C CN 1082051C CN 96198101 A CN96198101 A CN 96198101A CN 96198101 A CN96198101 A CN 96198101A CN 1082051 C CN1082051 C CN 1082051C
Authority
CN
China
Prior art keywords
meleu
phlac
lac
alkoxy
alkylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN96198101A
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English (en)
Chinese (zh)
Other versions
CN1201456A (zh
Inventor
阪中治
冈田裕美子
大山真
松本麻纪
高桥正明
村井安
饭沼胜春
A·哈德
N·门克
G·邦斯
P·杰什克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Meiji Seika Kaisha Ltd filed Critical Bayer AG
Publication of CN1201456A publication Critical patent/CN1201456A/zh
Application granted granted Critical
Publication of CN1082051C publication Critical patent/CN1082051C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN96198101A 1995-09-22 1996-09-20 新的环缩肽pf1022物质的衍生物 Expired - Lifetime CN1082051C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP244051/95 1995-09-22
JP24405195 1995-09-22

Publications (2)

Publication Number Publication Date
CN1201456A CN1201456A (zh) 1998-12-09
CN1082051C true CN1082051C (zh) 2002-04-03

Family

ID=17113003

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96198101A Expired - Lifetime CN1082051C (zh) 1995-09-22 1996-09-20 新的环缩肽pf1022物质的衍生物

Country Status (18)

Country Link
US (1) US6329338B1 (https=)
EP (1) EP0903347B1 (https=)
KR (1) KR19990063676A (https=)
CN (1) CN1082051C (https=)
AT (1) ATE299871T1 (https=)
AU (1) AU727532B2 (https=)
BR (1) BR9610527A (https=)
CA (1) CA2232668C (https=)
CZ (1) CZ295705B6 (https=)
DE (1) DE69634961T2 (https=)
DK (1) DK0903347T3 (https=)
ES (1) ES2246496T3 (https=)
HU (1) HU228004B1 (https=)
IL (1) IL123776A (https=)
NO (1) NO310622B1 (https=)
NZ (1) NZ318515A (https=)
PL (1) PL186168B1 (https=)
WO (1) WO1997011064A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000029822A (ko) * 1996-08-07 2000-05-25 이치로 키타사토 환상데프시펩티드화합물의제조방법과새로운환상데프시펩티드
WO1998037088A1 (en) * 1997-02-19 1998-08-27 Meiji Seika Kaisha Ltd. Derivatives of cyclodepsipeptide, pf1022 substance
DE19811559A1 (de) * 1998-03-17 1999-09-23 Bayer Ag Cyclooctadepsipeptide
AU783603B2 (en) * 1999-09-29 2005-11-10 Meiji Seika Kaisha Ltd. Transformant producing secondary metabolite modified with functional group and novel biosynthesis genes
DE10031044A1 (de) * 2000-06-26 2002-01-03 Bayer Ag Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere
DE10104362A1 (de) * 2001-02-01 2002-08-08 Bayer Ag Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
DE102008022520A1 (de) 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
DE102008030764A1 (de) 2008-06-28 2009-12-31 Bayer Animal Health Gmbh Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden
DE102008031284A1 (de) * 2008-07-02 2010-01-07 Bayer Schering Pharma Aktiengesellschaft Neue Bekämpfungsmöglichkeit der Giardiose
DE102008031283A1 (de) * 2008-07-02 2010-01-07 Bayer Schering Pharma Aktiengesellschaft Neue Bekämpfungsmöglichkeit von durch Trichomonadida hervorgerufenen Krankheiten
DE102009012423A1 (de) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
DE102010064245A1 (de) 2010-12-28 2012-06-28 Bayer Animal Health Gmbh Makrocylischen Lactone und deren Verwendung und deren Kombinationen mit anderen Wirkstoffen
WO2012028556A1 (en) 2010-08-31 2012-03-08 Bayer Animal Health Gmbh Macrocyclic lactones and their use and their combinations with other active substances
LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
RU2715556C2 (ru) * 2015-12-28 2020-03-02 Мериал, Инк. Противогельминтные депсипептидные соединения
CA3044038A1 (en) 2016-11-16 2018-05-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
PL3676265T3 (pl) 2017-11-07 2025-12-15 Elanco Animal Health Gmbh Sposób syntezy cyklicznych depsypeptydów
AU2018374849B2 (en) 2017-11-29 2021-02-18 Zoetis Services Llc Endoparasitic depsipeptides
SG11202010187RA (en) 2018-05-10 2020-11-27 Zoetis Services Llc Endoparasitic depsipeptides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019053A1 (en) * 1992-03-17 1993-09-30 Fujisawa Pharmaceutical Co., Ltd. Depsipeptide derivative, production thereof and use thereof
WO1994019334A1 (fr) * 1993-02-19 1994-09-01 Meiji Seika Kaisha, Ltd. Derive du pf 1022 utilise comme depsipeptide cyclqiue

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH459977A (de) * 1965-05-18 1968-07-31 Agripat Sa Verfahren zur Herstellung von neuen Thiocarbaminsäureestern
EP0103895A3 (en) * 1982-09-22 1985-07-03 Meiji Seika Kabushiki Kaisha Novel hydroxylamine derivatives, production and use thereof
NO176766C (no) * 1989-02-07 1995-05-24 Meiji Seika Kaisha Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet
JP2873894B2 (ja) * 1992-10-19 1999-03-24 明治製菓株式会社 環状デプシペプチドおよびその製造法
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317432A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
JPH07233068A (ja) * 1993-12-27 1995-09-05 Meiji Seika Kaisha Ltd 高コレステロール血症、高脂血症又は動脈硬化症の治療薬

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019053A1 (en) * 1992-03-17 1993-09-30 Fujisawa Pharmaceutical Co., Ltd. Depsipeptide derivative, production thereof and use thereof
WO1994019334A1 (fr) * 1993-02-19 1994-09-01 Meiji Seika Kaisha, Ltd. Derive du pf 1022 utilise comme depsipeptide cyclqiue

Also Published As

Publication number Publication date
IL123776A0 (en) 1998-10-30
HUP0001164A3 (en) 2001-04-28
AU727532B2 (en) 2000-12-14
MX9802268A (es) 1998-08-30
JP4001381B1 (https=) 2007-10-31
EP0903347A4 (https=) 1999-03-24
CA2232668C (en) 2011-10-18
CZ85598A3 (cs) 1998-08-12
US6329338B1 (en) 2001-12-11
PL186168B1 (pl) 2003-11-28
IL123776A (en) 2002-09-12
ES2246496T3 (es) 2006-02-16
EP0903347B1 (en) 2005-07-20
DE69634961T2 (de) 2006-04-20
EP0903347A1 (en) 1999-03-24
WO1997011064A1 (en) 1997-03-27
HUP0001164A2 (hu) 2000-11-28
HU228004B1 (en) 2012-08-28
DK0903347T3 (da) 2005-11-21
ATE299871T1 (de) 2005-08-15
PL326024A1 (en) 1998-08-17
AU7001996A (en) 1997-04-09
NO981250D0 (no) 1998-03-19
CZ295705B6 (cs) 2005-10-12
KR19990063676A (ko) 1999-07-26
CN1201456A (zh) 1998-12-09
BR9610527A (pt) 1999-12-21
CA2232668A1 (en) 1997-03-27
NO981250L (no) 1998-05-22
NO310622B1 (no) 2001-07-30
NZ318515A (en) 2000-05-26
DE69634961D1 (de) 2005-08-25

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C06 Publication
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Free format text: FORMER OWNER: MEIJI SEIKA KAISHA,LTD.; BAYER AG

Effective date: 20060210

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Owner name: BAYER ANIMAL HEALTH PROMOTION CO.,LTD.

Free format text: FORMER OWNER: BAYER AG

Effective date: 20090515

C41 Transfer of patent application or patent right or utility model
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