CN1081877A - 用荷电树脂的球化方法 - Google Patents

用荷电树脂的球化方法 Download PDF

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Publication number
CN1081877A
CN1081877A CN93107621.8A CN93107621A CN1081877A CN 1081877 A CN1081877 A CN 1081877A CN 93107621 A CN93107621 A CN 93107621A CN 1081877 A CN1081877 A CN 1081877A
Authority
CN
China
Prior art keywords
composite particles
spherical composite
production
sodium
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93107621.8A
Other languages
English (en)
Chinese (zh)
Inventor
G·A·麦克里兰
G·M·曾特纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of CN1081877A publication Critical patent/CN1081877A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93107621.8A 1992-06-26 1993-06-25 用荷电树脂的球化方法 Pending CN1081877A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US906,226 1992-06-26
US07/906,226 US5350584A (en) 1992-06-26 1992-06-26 Spheronization process using charged resins

Publications (1)

Publication Number Publication Date
CN1081877A true CN1081877A (zh) 1994-02-16

Family

ID=25422115

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93107621.8A Pending CN1081877A (zh) 1992-06-26 1993-06-25 用荷电树脂的球化方法

Country Status (9)

Country Link
US (1) US5350584A (https=)
EP (1) EP0804167A1 (https=)
JP (1) JP2793042B2 (https=)
CN (1) CN1081877A (https=)
AU (1) AU4542393A (https=)
CA (1) CA2136435A1 (https=)
TW (1) TW242115B (https=)
WO (1) WO1994000111A1 (https=)
YU (1) YU41993A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107552777A (zh) * 2017-09-05 2018-01-09 昆山玛冀电子有限公司 一种用于电感生产的粉末颗粒成分及生产工艺

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ES2874669T3 (es) 2016-02-09 2021-11-05 Albireo Ab Formulación oral de colestiramina y uso de la misma
WO2017138878A1 (en) 2016-02-09 2017-08-17 Albireo Ab Oral cholestyramine formulation and use thereof
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EP3664782B1 (en) * 2017-08-09 2025-01-29 Albireo AB Cholestyramine pellets, oral cholestyramine formulations and medical use thereof
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CN112449637B (zh) 2018-06-05 2024-03-19 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
PL3810581T3 (pl) 2018-06-20 2025-04-28 Albireo Ab Modyfikacje kryształu odewiksibatu
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
CN118852054A (zh) 2019-02-06 2024-10-29 阿尔比里奥公司 苯并硫杂二氮杂环庚三烯化合物及其用作胆汁酸调节剂的用途
TWI835997B (zh) 2019-02-06 2024-03-21 瑞典商艾爾比瑞歐公司 苯并噻氮呯化合物及其用作膽酸調節劑之用途
ES2973355T3 (es) 2019-12-04 2024-06-19 Albireo Ab Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar
EP4069247B1 (en) 2019-12-04 2025-03-26 Albireo AB Benzothiadiazepine compounds and their use as bile acid modulators
JP7696898B2 (ja) 2019-12-04 2025-06-23 アルビレオ・アクチボラグ ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
IL293379B2 (en) 2019-12-04 2026-04-01 Albireo Ab Benzothia(dia)azepine compounds and their use as bile acid modulators
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107552777A (zh) * 2017-09-05 2018-01-09 昆山玛冀电子有限公司 一种用于电感生产的粉末颗粒成分及生产工艺

Also Published As

Publication number Publication date
CA2136435A1 (en) 1994-01-06
JP2793042B2 (ja) 1998-09-03
US5350584A (en) 1994-09-27
YU41993A (sh) 1997-01-08
AU4542393A (en) 1994-01-24
WO1994000111A1 (en) 1994-01-06
TW242115B (https=) 1995-03-01
EP0804167A1 (en) 1997-11-05
EP0804167A4 (https=) 1997-11-05
JPH07508280A (ja) 1995-09-14

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SE01 Entry into force of request for substantive examination
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