CN1081442A - 苯并二氮杂䓬 - Google Patents

苯并二氮杂䓬 Download PDF

Info

Publication number
CN1081442A
CN1081442A CN93107340A CN93107340A CN1081442A CN 1081442 A CN1081442 A CN 1081442A CN 93107340 A CN93107340 A CN 93107340A CN 93107340 A CN93107340 A CN 93107340A CN 1081442 A CN1081442 A CN 1081442A
Authority
CN
China
Prior art keywords
compound
formula
infections
hydrogen
retroviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93107340A
Other languages
English (en)
Chinese (zh)
Inventor
M-C·苏
D·M·赫因
S·Y·泰姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN1081442A publication Critical patent/CN1081442A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN93107340A 1992-06-16 1993-06-15 苯并二氮杂䓬 Pending CN1081442A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89919092A 1992-06-16 1992-06-16
US899,190 1992-06-16

Publications (1)

Publication Number Publication Date
CN1081442A true CN1081442A (zh) 1994-02-02

Family

ID=25410597

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93107340A Pending CN1081442A (zh) 1992-06-16 1993-06-15 苯并二氮杂䓬

Country Status (21)

Country Link
EP (1) EP0574781A2 (enExample)
JP (1) JPH0656825A (enExample)
KR (1) KR940005612A (enExample)
CN (1) CN1081442A (enExample)
AU (1) AU4123093A (enExample)
BG (1) BG97868A (enExample)
BR (1) BR9302359A (enExample)
CA (1) CA2098063A1 (enExample)
CZ (1) CZ115893A3 (enExample)
FI (1) FI932767L (enExample)
HU (1) HUT64536A (enExample)
IL (1) IL105977A0 (enExample)
IS (1) IS4035A (enExample)
LT (1) LT3028B (enExample)
MX (1) MX9303422A (enExample)
NO (1) NO932204L (enExample)
PL (1) PL299312A1 (enExample)
SI (1) SI9300288A (enExample)
SK (1) SK61593A3 (enExample)
UY (1) UY23600A1 (enExample)
ZA (1) ZA934077B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
WO1993018006A1 (en) 1992-03-11 1993-09-16 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5888992A (en) 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
CN2504706Y (zh) * 2001-09-25 2002-08-07 闽祥实业有限公司 具有触摸控制功能的平板显示屏
WO2004103360A1 (ja) 2003-05-22 2004-12-02 Lead Chemical Co.,Ltd. 抗ウイルス作用を有する化合物および配合剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL122319C (enExample) 1961-06-20
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
EP0475231A1 (en) * 1990-09-10 1992-03-18 F. Hoffmann-La Roche Ag Benzodiazepines
EP0491218A1 (en) * 1990-12-17 1992-06-24 F. Hoffmann-La Roche Ag Benzodiazepinones

Also Published As

Publication number Publication date
IS4035A (is) 1993-12-17
SI9300288A (sl) 1993-12-31
LTIP657A (en) 1994-05-15
LT3028B (en) 1994-08-25
BG97868A (en) 1994-05-27
CA2098063A1 (en) 1993-12-17
UY23600A1 (es) 1993-12-09
EP0574781A3 (enExample) 1994-04-06
SK61593A3 (en) 1994-01-12
NO932204D0 (no) 1993-06-15
KR940005612A (ko) 1994-03-21
FI932767A7 (fi) 1993-12-17
FI932767A0 (fi) 1993-06-16
NO932204L (no) 1993-12-17
JPH0656825A (ja) 1994-03-01
BR9302359A (pt) 1994-01-11
ZA934077B (en) 1993-12-16
FI932767L (fi) 1993-12-17
HUT64536A (en) 1994-01-28
AU4123093A (en) 1993-12-23
IL105977A0 (en) 1993-10-20
HU9301704D0 (en) 1993-09-28
MX9303422A (es) 1994-06-30
PL299312A1 (en) 1994-01-10
CZ115893A3 (en) 1994-01-19
EP0574781A2 (en) 1993-12-22

Similar Documents

Publication Publication Date Title
JP3442773B2 (ja) 抗ウイルス性ヌクレオシドコンビネーション
JPH1180153A (ja) １，３−オキサチオランヌクレオシド類似体
JP2014062116A (ja) 強力なｈｃｖ阻害剤である２−チアゾリル−４−キノリニル−オキシ誘導体の結晶形態
JPH07504673A (ja) 抗ウイルス活性を有するインドール誘導体
JPH06510041A (ja) 抗ｈｉｖ（ａｉｄｓ）薬剤
EP0548798A1 (en) Antiviral agent
JP2007525457A (ja) 置換１，４−ジアゼピン及びその使用
JP2006241161A (ja) ＭＤＭ２：ｐ５３相互作用の低分子インヒビターが関与する併用療法
CN1062528A (zh) 苯并二氮杂酮
EA000074B1 (ru) Способ получения циклопропилацетилена
JPH04230280A (ja) アミノベンゾジアゼピン類およびそれを含有している薬剤
JPH07504674A (ja) 抗ウイルス活性を有する更なるインドール誘導体
CN106536482A (zh) 具有抗hiv作用的苯基和叔丁基乙酸取代的吡啶酮
CN1081442A (zh) 苯并二氮杂䓬
CN111943906B (zh) 脒类衍生物、及其制法和药物组合物与用途
JPH04305578A (ja) ベンゾジアゼピン、その製造法、及び薬剤としての利用
JPH10509132A (ja) 抗ウィルス剤としてのピロロ（２，３−ｄ）ピリミジン誘導体
EP0586632A1 (en) Benzodiazepinones and medicines containing them
EP0552665A1 (en) Pyrrolylbenzodiazepinones and medicines containing them
JPH11508588A (ja) キナゾリン誘導体
JP3068175B2 (ja) イソチアゾロ〔５，４―ｂ〕ピリジン誘導体
CN1235601A (zh) (4R,5S,6S,7R)－六氢－1－[5－(3－氨基吲唑)甲基]－3－丁基－5,6－二羟基－4,7－双[苯甲基]－2H－1,3－二氮杂䓬－2－酮,它的制备及作为H<sub>2</sub>V蛋白酶抑制剂的应用
JPH06172365A (ja) １０−チアイソアロキサジン誘導体およびその用途
WO2013000108A1 (zh) 唑类杂环化合物、其制备方法、药物组合物和用途
JPH0352888A (ja) 新規化合物、その製法及びそれを含む医薬組成物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication