CN108137707A - 免疫检查点嵌合受体疗法 - Google Patents
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110267666A (zh) * | 2016-12-22 | 2019-09-20 | 温德弥尔治疗公司 | 用于调节免疫系统的组合物和方法 |
| CN113354710A (zh) * | 2016-12-09 | 2021-09-07 | 复诺健生物科技加拿大有限公司 | 用于抑制cd279相互作用的组合物和方法 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201505858VA (en) | 2013-01-28 | 2015-09-29 | St Jude Childrens Res Hospital | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| JP6431920B2 (ja) | 2013-09-17 | 2018-11-28 | オービーアイ ファーマ，インコーポレイテッド | 免疫反応を誘導する炭水化物ワクチンの組成とがんの治療におけるその使用 |
| EP3143134B1 (en) | 2014-05-15 | 2020-10-28 | National University of Singapore | Modified natural killer cells and uses thereof |
| KR20180029201A (ko) | 2015-05-18 | 2018-03-20 | 티씨알2 테라퓨틱스 인크. | 융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법 |
| MA42902A (fr) | 2015-07-08 | 2018-05-16 | Univ Johns Hopkins | Lymphocytes infiltrant la moelle (mil) en tant que source de lymphocytes t pour une thérapie par des récepteurs chimériques d'un antigène (car) |
| EP4286522A3 (en) * | 2016-03-23 | 2024-02-28 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins of pd-1 and 4-1bb |
| US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| MY200886A (en) | 2016-04-22 | 2024-01-22 | Obi Pharma Inc | Cancer Immunotherapy by Immune Activation or Immune Modulation Via Globo Series Antigens |
| JP2019527690A (ja) | 2016-07-27 | 2019-10-03 | オービーアイ ファーマ，インコーポレイテッド | 免疫原性／治療用グリカン組成物およびその使用 |
| US11643456B2 (en) | 2016-07-29 | 2023-05-09 | Obi Pharma, Inc. | Human antibodies, pharmaceutical compositions and methods |
| TWI767959B (zh) | 2016-11-21 | 2022-06-21 | 台灣浩鼎生技股份有限公司 | 共軛生物分子、醫藥組成物及方法 |
| JP7291396B2 (ja) | 2016-11-22 | 2023-06-15 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法 |
| EP3601537A4 (en) | 2017-03-27 | 2021-01-13 | National University of Singapore | STIMULATING CELL LINES FOR EX VIVO EXPANSION AND ACTIVATION OF NATURAL KILLER CELLS |
| SG11201908492PA (en) | 2017-03-27 | 2019-10-30 | Nat Univ Singapore | Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy |
| WO2018191490A1 (en) * | 2017-04-13 | 2018-10-18 | The Trustees Of The University Of Pennsylvania | Use of gene editing to generate universal tcr re-directed t cells for adoptive immunotherapy |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| KR20200138741A (ko) | 2018-04-02 | 2020-12-10 | 내셔널 유니버시티 오브 싱가포르 | 면역 세포에서 발현되는 막-결합 항-사이토카인 비-신호전달 결합제를 이용한 인간 사이토카인의 중화 |
| JP7560882B2 (ja) | 2018-08-29 | 2024-10-03 | ナショナル ユニヴァーシティー オブ シンガポール | 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法 |
| CA3120323A1 (en) * | 2018-11-30 | 2020-06-04 | Windmil Therapeutics, Inc. | Marrow infiltrating lymphocytes (mils) expressing chimeric antigen receptors (car), method of manufacturing same, and method of using in therapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | ANTI-CD19 CHEMERIC ANTIGEN RECEPTORS AND THEIR USE IN IMMUNOTHERAPY |
| WO2022098985A1 (en) * | 2020-11-05 | 2022-05-12 | Windmil Therapeutics, Inc. | Glioblastoma specific marrow infiltrating lymphocytes and uses thereof |
| IL302947A (en) * | 2020-11-19 | 2023-07-01 | Obi Pharma Inc | Active cancer immunotherapy by immune modulation via globo series antigens |
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| US20140242049A1 (en) * | 2011-10-26 | 2014-08-28 | National Cancer Center | Mutant ctla4 gene transfected t cell and composition including same for anticancer immunotherapy |
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| WO2016037054A1 (en) * | 2014-09-04 | 2016-03-10 | The Johns Hopkins University | Activation of marrow infiltrating lymphocytes in hypoxic alternating with normoxic conditions |
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| AU2014266833B2 (en) * | 2013-05-13 | 2020-07-02 | Cellectis | Methods for engineering highly active T cell for immunotherapy |
| EP3087101B1 (en) * | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| US20170209492A1 (en) * | 2014-07-31 | 2017-07-27 | Novartis Ag | Subset-optimized chimeric antigen receptor-containing t-cells |
| PT3310805T (pt) * | 2015-06-19 | 2021-05-19 | Kobold Sebastian | Proteínas de fusão pd-1-cd28 e a sua utilização em medicina |
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| CN110267666A (zh) * | 2016-12-22 | 2019-09-20 | 温德弥尔治疗公司 | 用于调节免疫系统的组合物和方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1255637A1 (zh) | 2019-08-23 |
| IL256643A (en) | 2018-02-28 |
| JP2018520679A (ja) | 2018-08-02 |
| HK1254820A1 (zh) | 2019-07-26 |
| US20180185434A1 (en) | 2018-07-05 |
| MA42272A (fr) | 2018-05-02 |
| WO2017004150A1 (en) | 2017-01-05 |
| AU2016285859A1 (en) | 2018-02-15 |
| MX2018000278A (es) | 2018-03-08 |
| EP3313892A4 (en) | 2019-01-02 |
| KR20180038447A (ko) | 2018-04-16 |
| EP3313892A1 (en) | 2018-05-02 |
| CA2991040A1 (en) | 2017-01-05 |
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