CN108137677A - 抗pacap抗体及其用途 - Google Patents
抗pacap抗体及其用途 Download PDFInfo
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- CN108137677A CN108137677A CN201680034721.1A CN201680034721A CN108137677A CN 108137677 A CN108137677 A CN 108137677A CN 201680034721 A CN201680034721 A CN 201680034721A CN 108137677 A CN108137677 A CN 108137677A
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- pacap
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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Abstract
Description
抗体 | ka(1/Ms) | kd(1/s) | KD(M) |
Ab10 | 2.6E+05 | 2.0E-05 | 7.5E-11 |
Ab20 | 1.2E+05 | 2.4E-05 | 2.1E-10 |
Ab21 | 3.7E+05 | 1.0E-05 | 2.7E-11 |
Ab22 | 3.7E+05 | 1.0E-05 | 2.7E-11 |
Ab23 | 5.1E+05 | 3.6E-05 | 7.1E-11 |
Ab1.H | 4.7E+05 | 1.0E-05 | 2.1E-11 |
Ab10.H | 3.4E+05 | 1.0E-05 | 2.9E-11 |
Ab21.H | 4.8E+05 | 1.0E-05 | 2.1E-11 |
抗体 | ka(1/Ms) | kd(1/s) | KD(M) |
Ab10 | 1.0E+06 | 1.0E-05 | 1.0E-11 |
Ab20 | 3.2E+05 | 2.2E-05 | 7.0E-11 |
Ab21 | 7.9E+05 | 1.0E-05 | 1.3E-11 |
Ab22 | 1.0E+00 | 1.0E-01 | 1.0E-01 |
Ab23 | 8.9E+05 | 3.1E-02 | 3.5E-08 |
Ab1.H | 7.6E+05 | 1.0E-05 | 1.3E-11 |
Ab10.H | 5.3E+05 | 1.8E-05 | 3.3E-11 |
Ab21.H | 6.3E+05 | 1.0E-05 | 1.6E-11 |
抗体 | IC50(nM) |
Ab1.H | 0.70 |
Ab10.H | 0.22 |
Ab21.H | 0.39 |
Claims (89)
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