CN107922941A - 在自动化反应盒中DNA甲基化的整合的纯化和测量以及突变和/或mRNA表达水平的共同测量 - Google Patents

在自动化反应盒中DNA甲基化的整合的纯化和测量以及突变和/或mRNA表达水平的共同测量 Download PDF

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CN107922941A
CN107922941A CN201680048155.XA CN201680048155A CN107922941A CN 107922941 A CN107922941 A CN 107922941A CN 201680048155 A CN201680048155 A CN 201680048155A CN 107922941 A CN107922941 A CN 107922941A
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dna
methylation
sample
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cassette
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E·W·赖
A·科尔维
R·范阿塔
R·希古奇
A·加尔
K·考克蒙德
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Cepheid
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    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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CN201680048155.XA 2015-06-15 2016-06-14 在自动化反应盒中DNA甲基化的整合的纯化和测量以及突变和/或mRNA表达水平的共同测量 Pending CN107922941A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562175916P 2015-06-15 2015-06-15
US62/175,916 2015-06-15
PCT/US2016/037422 WO2016205233A2 (en) 2015-06-15 2016-06-14 Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge

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CN107922941A true CN107922941A (zh) 2018-04-17

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US (2) US11603555B2 (https=)
EP (2) EP3307885B1 (https=)
JP (2) JP7020922B2 (https=)
CN (1) CN107922941A (https=)
AU (3) AU2016277943B2 (https=)
CA (1) CA2989573A1 (https=)
ES (1) ES2842205T3 (https=)
WO (1) WO2016205233A2 (https=)

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CN108456721A (zh) * 2018-05-16 2018-08-28 基因科技（上海）股份有限公司 同步检测基因突变和甲基化的方法及其应用
CN108753979A (zh) * 2018-07-09 2018-11-06 安徽达健医学科技有限公司 一种用于肝癌早期筛查的试剂盒及其使用方法
CN110267744A (zh) * 2016-12-12 2019-09-20 塞弗德公司 在自动化反应盒中DNA甲基化的整合的纯化和测量以及突变和/或mRNA表达水平的共同测量
WO2020019268A1 (zh) * 2018-07-26 2020-01-30 北京艾克伦医疗科技有限公司 鉴定乳腺癌状态的方法和试剂盒
CN110964813A (zh) * 2018-09-29 2020-04-07 广州市康立明生物科技有限责任公司 Hoxa7甲基化检测试剂在制备肺癌诊断试剂中的用途
CN111088351A (zh) * 2018-10-23 2020-05-01 博尔诚（北京）科技有限公司 用于检测肺癌的组合物及其用途
CN111662980A (zh) * 2020-06-03 2020-09-15 广州市康立明生物科技有限责任公司 一种肺癌检测试剂及试剂盒
WO2020252721A1 (en) * 2019-06-20 2020-12-24 The Johns Hopkins University Dna methylation markers and their use in differentiation of suspected cancerous lymph node biopsy samples
WO2021243904A1 (zh) * 2020-06-03 2021-12-09 广州康立明生物科技股份有限公司 一种基因标志物组合及其应用
US11603555B2 (en) 2015-06-15 2023-03-14 Cepheid Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or MRNA expression levels in an automated reaction cartridge

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CN108277274A (zh) * 2017-01-03 2018-07-13 博尔诚（北京）科技有限公司 用于区分胰腺癌和慢性胰腺炎的组合物及其用途
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CN107164535A (zh) * 2017-07-07 2017-09-15 沈阳宁沪科技有限公司 一种无创高通量甲基化结肠癌诊断、研究和治疗方法
US11466323B2 (en) * 2017-07-13 2022-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Dual-probe digital droplet PCR strategy for specific detection of tissue-specific circulating DNA molecules
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CN107868813B (zh) * 2017-11-16 2021-07-27 上海覃谷生物技术有限公司 一种血浆dna边提取边转化的方法及应用
CN119753091A (zh) 2018-04-02 2025-04-04 格里尔公司 用于扩增与癌症相关联的cfDNA分子的化验板
CN108300787A (zh) * 2018-04-17 2018-07-20 中国科学院北京基因组研究所 特异甲基化位点作为乳腺癌早期诊断标志物的应用
CN108531595A (zh) * 2018-04-25 2018-09-14 新疆医科大学附属肿瘤医院 检测待测dna甲基化的引物组合物、检测方法及应用
CN108676879A (zh) * 2018-05-24 2018-10-19 中国科学院北京基因组研究所 特异甲基化位点作为乳腺癌分子分型诊断标志物的应用
CN108796080B (zh) * 2018-06-06 2022-06-07 苏州唯善生物科技有限公司 用于结直肠癌诊断、检测或筛查的引物和探针组
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WO2020257404A1 (en) * 2019-06-20 2020-12-24 The Johns Hopkins University Dna markers for differentiation of biopsy samples
CN113930499B (zh) * 2020-06-29 2023-09-22 武汉艾米森生命科技有限公司 检测基因甲基化的试剂的应用以及结直肠癌诊断或辅助诊断试剂盒
CN114085894A (zh) * 2021-11-03 2022-02-25 翌圣生物科技(上海)股份有限公司 核酸甲基化胞嘧啶转化方法
WO2023133533A2 (en) * 2022-01-06 2023-07-13 The University Of Chicago Methods and compositions for rapid detection and analysis of rna and dna cytosine methylation
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