CN107714530A - It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray - Google Patents

It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray Download PDF

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Publication number
CN107714530A
CN107714530A CN201710882867.8A CN201710882867A CN107714530A CN 107714530 A CN107714530 A CN 107714530A CN 201710882867 A CN201710882867 A CN 201710882867A CN 107714530 A CN107714530 A CN 107714530A
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China
Prior art keywords
oral hygiene
oral
oral cavity
hygiene spray
antibacterial
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Pending
Application number
CN201710882867.8A
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Chinese (zh)
Inventor
薛建龙
常雪妮
蒋丽娟
谢知芳
基特·彦姆
迈克尔·里奥尼德斯·崎肯德思
纳泽·米尔
冯立雄
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Qiaokang Biotech Guangdong Co Ltd
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Xi'an Rogers Biological Science And Technology Co Ltd
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Priority to CN201710882867.8A priority Critical patent/CN107714530A/en
Publication of CN107714530A publication Critical patent/CN107714530A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/046Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Present invention offer is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray, belongs to daily chemicals field.According to weight meter, the oral hygiene spray includes 0.00005%~0.003% deionized water for going removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~5% plant extracts, 5%~20% moisturizing stabilizer, 0.001%~0.2% surfactant, 0.05%~2% flavouring, 0.01%~0.05% pH value regulator, 0.000009%~0.000015% food coloring and surplus.Wherein, removing abnormal flavor in oral cavity/antibacterial substance can Efficient antibacterial, to the bacteriostasis rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;Flavorants can realize the lasting pure and fresh of implication.

Description

It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray
Technical field
It is more particularly to a kind of to be used to going removing abnormal flavor in oral cavity, antibacterial, fresh breath the invention belongs to daily chemicals field Oral hygiene spray.
Background technology
With the development of the society, people also increasingly improve for the health care demand in oral cavity.It is but at the same time, pre- due to lacking Anti- and treatment, China's mouth disease illness rate is high, scope is wide, and the permanent teeth caries prevalence rate of adult is 49.88%, children's Primary Caries rate 80%th, periodontosis illness rate about 90%, 65-74 year old man averagely lose tooth number and are up to 11.If by all mouth disease bags Including including (such as canker sore, toothache, periodontitis, bleeding gums, calculus dentalis, halitosis), it may be said that almost everybody has oral cavity Disease, the incidence of disease are almost 100%.Meanwhile there is smoker more than 300,000,000 in China, the xanthodont cigarette tooth rate of black tooth is more than 90%, if counting coffee in Coffee stain, tea stain, the crowd of betel nut stain and bacterial plaque, Chinese at least 800,000,000 people need tooth whitening.Various mouth diseases are prevented and treated, Except drug therapy, regular oral health routine holds the balance, outer except periodically brushing teeth, and researches and develops one kind and is convenient for carrying, convenient use, kills Bacterium anti-inflammatory, the oral hygiene spray in nursing oral cavity become extremely significant.
The health care in oral cavity includes preventing carious tooth, suppress oral bacteria and removing removing abnormal flavor in oral cavity.These problems are oral cavity anaerobism Bacterium, host and three big factor interaction of diet cause, and the effect of bacterium accounts for significant proportion.These anaerobic bacterias decompose food Protein in thing residue and saliva, a variety of gases for having peculiar smell are produced, many people is produced halitosis, many normal persons are due to night Between salivary secretion reduce and occur oral peculiar smell when from morning, have a strong impact on the social activity image of people, influence the life matter of people Amount.Chlorine dioxide antiseptic power is strong, has a broad antifungal spectrum, has volume killing action to bacterium, virus, fungi and gemma etc., and act on fast Speed, bactericidal effect is small by environmental condition (temperature, pH value, organic matter) influence, nontoxic, non-stimulated, environmentally safe, in America and Europe Country is used in many oral care products, for tooth whitening and health care, pre- anti-caries and periodontal disease, in particular for The preventing and treating of halitosis.Experimental results demonstrate Chlorine Dioxide In Killing oral cavity anaerobium, fundamentally treat halitosis in terms of positive effect it is good In other its products.Tea Polyphenols has inhibitory action to microorganisms such as Escherichia coli, staphylococcus, bacillus subtilises, is added It is added in gargle, not only can be with antibacterial, while the flavor of rinse product can be enriched.And chlorine dioxide is used in China The product of oral care is few, and the oral hygiene spray for adding Tea Polyphenols is even more very few.
The content of the invention
It is an object of the invention to provide a kind of oral hygiene spray, for removing removing abnormal flavor in oral cavity, antibacterial, fresh breath.
The present invention is to be achieved through the following technical solutions:
A kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray, according to weight meter, the oral cavity is defended Raw spray include 0.00005%~0.003% go removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~5% plant extracts, 5%~20% moisturizing stabilizer, 0.001%~0.2% surfactant, 0.05%~2% flavouring, 0.01%~ 0.05% pH value regulator, 0.000009%~0.000015% food coloring, 0.03%~1% flavorants and The deionized water of surplus.
Preferably, the described removing abnormal flavor in oral cavity/antibacterial substance that goes is chlorine dioxide.
Preferably, described plant extracts is that black tea extract solution, green tea extractive liquor, white snow tea extract and blood-snow tea carry Take the one or more in liquid.
Preferably, described moisturizing stabilizer is propane diols and glycerine.
Preferably, described surfactant be Tween-80, poloxamer188 and sldium lauryl sulfate in one kind or It is several.
Preferably, described flavouring is one in saccharin sodium, acesulfame potassium, stevioside, xylitol and D-sorbite Kind is several.
Preferably, the pH value regulator is the mixture of citric acid and sodium acid carbonate.
Preferably, described food coloring be chlorophyll mantoquita sodium, compounding it is apple green and compounding tender leaf it is green in one kind or It is several.
Preferably, described flavorants are water-soluble Mint Essence, menthol and one kind or several in peppermint hydrosol Kind.
Preferably, the oral hygiene spray solution formed after all components are well mixed is packed using aluminium aerosol bottle.
It is further preferred that the mass ratio of propane diols and glycerine is (2.5~4):1.
It is further preferred that pH value regulator make it that the pH value of oral hygiene spray is 6.8~7.2.
Compared with prior art, the present invention has technique effect beneficial below:
Oral hygiene spray provided by the invention, including removing abnormal flavor in oral cavity/antibacterial substance, plant extracts, moisturizing stabilization Agent, surfactant, flavouring, pH value regulator, flavorants and food coloring.Removing abnormal flavor in oral cavity/antibacterial substance can Efficient antibacterial, to the bacteriostasis rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;Flavorants can realize implication It is lasting pure and fresh, it is long-term use of, be advantageous to the health care of many people, can less mouth disease generation.Compared with prior art, it is adapted to Consumers in general, it is especially suitable for doings ratio more frequently personage, formula has more specific aim, and composition is safe, and with Spray form is present, and has and absorbs the advantages of rapid, easy to use, widely applicable.
Brief description of the drawings
Fig. 1 be oral hygiene spray to garlic flavour removal effect figure, wherein, " processing " be handled using oral hygiene spray Blank sheet of paper, " control " is the blank sheet of paper that is not handled by oral hygiene spray.
Fig. 2 is inhibition of the oral hygiene spray to different microorganisms.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and It is not to limit.
It is an object of the invention to provide a kind of oral hygiene spray, suitable for all groups, is mainly used in removing oral cavity Peculiar smell, antibacterial, fresh breath.
The mouth sprays include go removing abnormal flavor in oral cavity/antibacterial substance, plant extracts, moisturizing stabilizer, surfactant, Flavouring, pH value regulator, food coloring, flavorants and deionized water.Its concrete component and percentage by weight are as follows:
1) removing abnormal flavor in oral cavity/antibacterial substance is gone to select high-pure chlorinedioxide, its percentage by weight is 0.00005%~ 0.003%, preferably 0.0003%~0.001%, for removing removing abnormal flavor in oral cavity, antibacterial;
2) plant extracts from black tea extract solution, green tea extractive liquor, avenge tea extract, one in blood-snow tea extract in vain Kind or several, preferred green tea extractive liquor, its percentage by weight be 0.1%~5%, preferably 1.0%~2.5%, for antibacterial and As flavor substance;
3) moisturizing stabilizer selects propane diols and glycerine, and percentage by weight is 5%~20%, preferably 12%~16%;
4) surfactant is preferably moored from the one or more in Tween-80, poloxamer188, sldium lauryl sulfate Luo Shamu 407, percentage by weight are 0.001%~0.2%, preferably 0.015%;
5) flavouring is excellent from the one or more in saccharin sodium, acesulfame potassium, stevioside, xylitol, D-sorbite Selecting acesulfame potassium, stevioside, xylitol and D-sorbite, percentage by weight is 0.05%~2%, preferably 0.09%~ 0.3%, as sweetener;
6) food coloring from chlorophyll mantoquita sodium, compounding it is apple green, compounding tender leaf it is green in one or more, it is preferably multiple With apple green, percentage by weight is 0.000009%~0.000015%, preferably 0.000011-0.000014%;
7) for pH value regulator from citric acid and the mixture of sodium acid carbonate, percentage by weight is 0.01%~0.05%.
8) flavorants are from the one or more in water-soluble Mint Essence, menthol, peppermint hydrosol, preferably peppermint Alcohol and peppermint hydrosol, percentage by weight are 0.03%~1%, preferably 0.1%~0.5%.Its not only can with fresh breath, and It can refresh the mind;
9) surplus is deionized water.
The preparation method of the oral spray of the present invention:Above-mentioned all components are added in appropriate amount of deionized water and dissolved, it is fixed Packed after appearance using aluminium aerosol bottle.
Oral hygiene spray provided by the invention, wherein removing abnormal flavor in oral cavity and antibacterial material are added, it is long-term use of, Be advantageous to the health care of many people, can less mouth disease generation;It with the addition of the thing flavorants to refresh the mind while have The function of refreshing the mind, available for work, study when refresh oneself or human communication in adjust oral cavity smell.Compared with prior art, It is adapted to consumers in general, is especially suitable for doings ratio more frequently personage, formula has more specific aim, and composition is safe, And exist with spray form, have and absorb the advantages of rapid, easy to use, widely applicable.
Oral hygiene spray provided by the invention has advantages below:
1. Efficient antibacterial --- to the bacteriostasis rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;
2. fresh breath --- oral peculiar smell can be quickly eliminated, effectively prevention, alleviation halitosis, possess pure and fresh mouth whenever and wherever possible Gas;
3. deeply cleaning --- the deep spot being hidden in teeth space can be quickly removed, and gos deep into pharyngeal cleaning oral cavity comprehensively;
4. avoid wearing --- avoid brushing teeth the enamel abrasion brought, makes tooth more bright and clean charming;
5. avoid bleeding --- caused bleeding gums of brushing teeth are avoided, make oral cavity anti-virus ability stronger;
6. nursing is comprehensive --- it is simple to spray, sterilize, clean the teeth, the completion of the step of permanent tooth one, being more simply, more easily Oral care method.
Embodiment 1
Preparation method:All the components are added in appropriate amount of deionized water and dissolved, are packed after constant volume using aluminium aerosol bottle.
Embodiment 2
Preparation method:All the components are added in appropriate amount of deionized water and dissolved, are packed after constant volume using aluminium aerosol bottle.
Embodiment 3
Preparation method:All the components are added in appropriate amount of deionized water and dissolved, are packed after constant volume using aluminium aerosol bottle.
The effect of oral hygiene spray provided by the invention is illustrated below.
The oral hygiene spray of embodiment 4 eliminates garlic flavour
Mouth sprays are prepared according to embodiment 1,7g mashed garlic is applied to blank sheet of paper center in a manner of rolling, sprayed with oral hygiene Agent uniformly spray 3 times on blank sheet of paper central point, blank sheet of paper is placed at dry shady and cool ventilation, every 1min, is evaluated garlicky dense on blank sheet of paper Degree, evaluate the people of number 10.Initial garlicky concentration is designated as 100, is designated as 0 without garlicky, other take same time point according to deep or light marking More people's marking averages are the time point garlicky concentration score value, using the score value and the percentage of initial garlicky concentration as garlicky residual Rate, residual rate are more low better.Residual rate result is shown in Fig. 1.As a result show, when the oral hygiene spray for being sprayed with the present invention Afterwards, on blank sheet of paper it is garlicky it is rapid eliminate, can reduce about 90% when about 50%, three minutes can be reduced at one minute, eight minutes When garlicky basic disappear;Without treated blank sheet of paper, at three minutes it is garlicky still have about 95% residual, garlic at eight minutes Taste residual about 90%.Therefore, oral hygiene spray of the invention can be eliminated significantly garlicky, and this shows that the oral cavity of the present invention is defended Raw spray has splendid effect in elimination oral peculiar smell field.
The fungistatic effect of embodiment 5 is tested
The oral hygiene spray that embodiment 1 obtains is surveyed according to fungistatic effect method of testing described in GB15979-2002 It is fixed, calculate bacteriostasis rate (%).Experimental results show in fig. 2, wherein, if bacteriostasis rate is X%, logarithm bacteriostasis rate is lgX. Experiment shows that oral hygiene spray of the invention (are read to Common detrimental microorganism by staphylococcus aureus, Escherichia coli, white Pearl coccus) inhibiting rate reach more than 99%, there is good fungistatic effect.

Claims (10)

1. a kind of be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray, it is characterised in that according to weight meter, The oral hygiene spray includes 0.00005%~0.003% and goes removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~5% plant Extract, 5%~20% moisturizing stabilizer, 0.001%~0.2% surfactant, 0.05%~2% flavouring, 0.01%~0.05% pH value regulator, 0.000009%~0.000015% food coloring, 0.03%~1% implication The deionized water of freshener and surplus.
2. oral hygiene spray according to claim 1, it is characterised in that:Described removes removing abnormal flavor in oral cavity/antibacterial substance For chlorine dioxide.
3. oral hygiene spray according to claim 1, it is characterised in that described plant extracts extracts for black tea One or more in liquid, green tea extractive liquor, white snow tea extract and blood-snow tea extract.
4. oral hygiene spray according to claim 1, it is characterised in that described moisturizing stabilizer is propane diols and sweet Oil.
5. oral hygiene spray according to claim 1, it is characterised in that described surfactant is Tween-80, pool One or more in Luo Shamu 407 and sldium lauryl sulfate.
6. oral hygiene spray according to claim 1, it is characterised in that described flavouring be saccharin sodium, acesulfame potassium, One or more in stevioside, xylitol and D-sorbite.
7. oral hygiene spray according to claim 1, it is characterised in that the pH value regulator is citric acid and carbonic acid The mixture of hydrogen sodium.
8. oral hygiene spray according to claim 1, it is characterised in that described food coloring is chlorophyll mantoquita Sodium, compounding it is apple green and compounding tender leaf it is green in one or more.
9. oral hygiene spray according to claim 1, it is characterised in that described flavorants are water-soluble peppermint One or more in essence, menthol and peppermint hydrosol.
10. oral hygiene spray according to claim 1, it is characterised in that the mouth formed after all components are well mixed Chamber health spray solution is packed using aluminium aerosol bottle.
CN201710882867.8A 2017-09-26 2017-09-26 It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray Pending CN107714530A (en)

Priority Applications (1)

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CN201710882867.8A CN107714530A (en) 2017-09-26 2017-09-26 It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray

Applications Claiming Priority (1)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110013451A (en) * 2019-05-16 2019-07-16 华纳时代健康科技(武汉)股份有限公司 A kind of oral bacteriostasis liquid and production technology
CN111494263A (en) * 2020-04-30 2020-08-07 云南风联科技有限公司 Plant tea-flavored oral cavity atomized liquid and preparation method thereof
CN111603418A (en) * 2020-04-23 2020-09-01 广州宏康医药科技有限公司 Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof
CN113368007A (en) * 2021-06-25 2021-09-10 艾依诺科技有限公司 Multifunctional aerosol for oral cavity and preparation process thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN101167690A (en) * 2006-10-23 2008-04-30 王俊二 Oral cleaning composition
CN103768435A (en) * 2014-01-21 2014-05-07 江苏中烟工业有限责任公司 Breath-freshening type tobacco oral cavity spray and preparation method thereof
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN101167690A (en) * 2006-10-23 2008-04-30 王俊二 Oral cleaning composition
CN103768435A (en) * 2014-01-21 2014-05-07 江苏中烟工业有限责任公司 Breath-freshening type tobacco oral cavity spray and preparation method thereof
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110013451A (en) * 2019-05-16 2019-07-16 华纳时代健康科技(武汉)股份有限公司 A kind of oral bacteriostasis liquid and production technology
CN111603418A (en) * 2020-04-23 2020-09-01 广州宏康医药科技有限公司 Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof
CN111494263A (en) * 2020-04-30 2020-08-07 云南风联科技有限公司 Plant tea-flavored oral cavity atomized liquid and preparation method thereof
CN113368007A (en) * 2021-06-25 2021-09-10 艾依诺科技有限公司 Multifunctional aerosol for oral cavity and preparation process thereof

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