CN111603418A - Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof - Google Patents

Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof Download PDF

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Publication number
CN111603418A
CN111603418A CN202010325224.5A CN202010325224A CN111603418A CN 111603418 A CN111603418 A CN 111603418A CN 202010325224 A CN202010325224 A CN 202010325224A CN 111603418 A CN111603418 A CN 111603418A
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care product
oral care
solution
oral cavity
stirring
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肖军宏
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Guangzhou Hongkang Pharmaceutical Technology Co ltd
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Guangzhou Hongkang Pharmaceutical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a lasting fresh antibacterial oral care product and a preparation method thereof, wherein the oral care product comprises the following components in percentage by mass: nutgall: 1% -20%, water: 1% -80%, surfactant: 0.2% -0.7%, glycerin: 1% -5% of humectant: 1% -5%, orange fruit extract: 0.1% -0.2%, sweetener: 1% -4% of edible essence: 1.0% -1.5%, poloxamer 407: 1% -5%, cetylpyridinium chloride: 0.01% -0.2% and disodium EDTA: 0.1% -1%, the beneficial effects of the invention are: the newly added nutgall component of the vitamin medicine can solve various oral cavity problems, deeply clean the oral cavity, inhibit bacteria, diminish inflammation, maintain periodontal health, and the design of the foam carrier can deeply clean pathogenic bacteria deeply hidden in the slits of teeth, permeate corners of the oral cavity, nurse the oral cavity at 360 degrees, and thoroughly clean the oral cavity environment. The oral care product can maintain fresh breath for a long time, effectively remove tooth stains, solve pigmentation in the oral cavity, effectively solve the problem of dental yellowing, reduce peculiar smell and refresh the breath.

Description

Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof
Technical Field
The invention relates to the technical field of oral care, in particular to a durable fresh antibacterial oral care product and a preparation method thereof.
Background
With the improvement of living standard, the sweet food is increased, which brings some adverse consequences, especially oral diseases, halitosis, etc.; the oral cavity is a long-term subject to inhibit bacteria and prevent diseases from entering the mouth. Breath freshening is also a very important part of everyday life and is a fashion, and therefore there are considerable consumer demands for products that freshen breath or clean the mouth. However, most of the existing oral cavity delivery preparations such as chewing gum and the like use sugar and gum as main raw materials, which cannot effectively kill oral cavity pathogenic bacteria, and use oral cavity cleaning products such as toothbrush or dental floss and the like increases burden and is inconvenient to carry outdoors or in traveling.
Disclosure of Invention
The invention aims to provide a long-lasting fresh antibacterial oral care product and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the aim, the invention provides the following technical scheme, namely the oral care product with lasting freshness and bacteriostasis, which comprises the following components in percentage by mass: nutgall: 1% -20%, water: 1% -80%, surfactant: 0.2% -0.7%, glycerin: 1% -5% of humectant: 1% -5%, orange fruit extract: 0.1% -0.2%, sweetener: 1% -4% of edible essence: 1.0% -1.5%, poloxamer 407: 1% -5%, cetylpyridinium chloride: 0.01% -0.2% and disodium EDTA: 0.1 to 1 percent.
Preferably, the gallnuts are washed, dried in the sun and smashed.
Preferably, the edible essence is water-soluble essence.
Preferably, the ratio of glycerol to propylene glycol is 1: 1.
Preferably, the humectant is propylene glycol.
Preferably, the surfactant is sodium lauroyl sarcosinate.
Preferably, the sweetener is one or a mixture of xylitol, saccharin sodium and acesulfame potassium.
A method of making a long lasting freshness bacteriostatic oral care product comprising the steps of:
s1, preparing a solution I: weighing xylitol, orange fruit extract, edible essence, sodium lauroyl sarcosinate, cetylpyridinium chloride and EDTA disodium according to the formula proportion, adding into partial water, heating and stirring until completely dissolving;
s2, preparing a solution II: weighing glycerol and propylene glycol according to the formula proportion, adding the glycerol and the propylene glycol together, uniformly mixing, adding the poloxamer 407, and uniformly mixing;
s3, preparing a solution III: weighing Galla Turcica according to formula ratio, adding into part of water, stirring to dissolve completely;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 30 minutes, adding the solution III, and continuing stirring for 10 minutes;
s5, filling: and (4) standing the mixed solution obtained in the step (4) for more than 12 hours, and then filling.
Compared with the prior art, the invention has the beneficial effects that:
1. the newly added nutgall component of the vitamin medicine can solve various oral problems, deeply clean the oral cavity, inhibit bacteria and diminish inflammation, and maintain periodontal health.
2. The design of the foam carrier can deeply clean pathogenic bacteria deeply hidden in the teeth slit, permeate corners of the oral cavity, care the oral cavity at 360 degrees and thoroughly clean the oral cavity environment. The oral care product can maintain fresh breath for a long time, effectively remove tooth stains, solve pigmentation in the oral cavity, effectively solve the problem of dental yellowing, reduce peculiar smell and refresh the breath.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a technical scheme that: a lasting fresh antibacterial oral care product comprises the following components in percentage by mass: nutgall: 1% -20%, water: 1% -80%, surfactant: 0.2% -0.7%, glycerin: 1% -5% of humectant: 1% -5%, orange fruit extract: 0.1% -0.2%, sweetener: 1% -4% of edible essence: 1.0% -1.5%, poloxamer 407: 1% -5%, cetylpyridinium chloride: 0.01% -0.2% and disodium EDTA: 0.1 to 1 percent.
Wherein the Galla Turcica is processed by cleaning, sun drying and mashing.
Wherein the edible essence is water-soluble essence.
Wherein the ratio of the glycerol to the propylene glycol is 1: 1.
Wherein the humectant is propylene glycol.
Wherein the surfactant is sodium lauroyl sarcosinate.
Wherein the sweetener is one or more of xylitol, saccharin sodium and acesulfame potassium.
A method of making a long lasting freshness bacteriostatic oral care product comprising the steps of:
s1, preparing a solution I: weighing xylitol, orange fruit extract, edible essence, sodium lauroyl sarcosinate, cetylpyridinium chloride and EDTA disodium according to the formula proportion, adding into partial water, heating and stirring until completely dissolving;
s2, preparing a solution II: weighing glycerol and propylene glycol according to the formula proportion, adding the glycerol and the propylene glycol together, uniformly mixing, adding the poloxamer 407, and uniformly mixing;
s3, preparing a solution III: weighing Galla Turcica according to formula ratio, adding into part of water, stirring to dissolve completely;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 30 minutes, adding the solution III, and continuing stirring for 10 minutes;
s5, filling: and (4) standing the mixed solution obtained in the step (4) for more than 12 hours, and then filling.
Example 1, a long-lasting fresh antibacterial oral care product, comprising the following components in percentage by mass: nutgall: 10% and water: 71%, sodium lauroyl sarcosinate: 0.5%, glycerin: 5%, propylene glycol: 5%, orange fruit extract: 0.1%, xylitol: 1% of edible essence: 1.2%, poloxamer 407: 5%, cetylpyridinium chloride: 0.2% and disodium EDTA: 1 percent.
Figure RE-GDA0002599773140000041
A method of making a long lasting freshness bacteriostatic oral care product comprising the steps of:
s1, preparing a solution I: weighing xylitol, orange fruit extract, edible essence, sodium lauroyl sarcosinate, cetylpyridinium chloride and EDTA disodium according to the formula proportion, adding into partial water, heating and stirring until completely dissolving;
s2, preparing a solution II: weighing glycerol and propylene glycol according to the formula proportion, adding the glycerol and the propylene glycol together, uniformly mixing, adding the poloxamer 407, and uniformly mixing;
s3, preparing a solution III: weighing Galla Turcica according to formula ratio, adding into part of water, stirring to dissolve completely;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 30 minutes, adding the solution III, and continuing stirring for 10 minutes;
s5, filling: and (4) standing the mixed solution obtained in the step (4) for more than 12 hours, and then filling.
Example 2, a long-lasting fresh antibacterial oral care product, comprising the following components in percentage by mass: nutgall: 15% and water: 66%, sodium lauroyl sarcosinate: 0.7%, glycerin: 5%, propylene glycol: 5%, orange fruit extract: 0.1%, xylitol: 1% of edible essence: 1%, poloxamer 407: 5%, cetylpyridinium chloride: 0.2% and disodium EDTA: 1 percent.
Figure RE-GDA0002599773140000051
A method of making a long lasting freshness bacteriostatic oral care product comprising the steps of:
s1, preparing a solution I: weighing xylitol, orange fruit extract, edible essence, sodium lauroyl sarcosinate, cetylpyridinium chloride and EDTA disodium according to the formula proportion, adding into partial water, heating and stirring until completely dissolving;
s2, preparing a solution II: weighing glycerol and propylene glycol according to the formula proportion, adding the glycerol and the propylene glycol together, uniformly mixing, adding the poloxamer 407, and uniformly mixing;
s3, preparing a solution III: weighing Galla Turcica according to formula ratio, adding into part of water, stirring to dissolve completely;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 30 minutes, adding the solution III, and continuing stirring for 10 minutes;
s5, filling: and (4) standing the mixed solution obtained in the step (4) for more than 12 hours, and then filling.
Furthermore, the terms "first", "second", "third", "fourth" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated, whereby the features defined as "first", "second", "third", "fourth" may explicitly or implicitly include at least one such feature.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. The oral care product with lasting freshness and bacteriostasis is characterized by comprising the following components in percentage by mass: nutgall: 1% -20%, water: 1% -80%, surfactant: 0.2% -0.7%, glycerin: 1% -5% of humectant: 1% -5%, orange fruit extract: 0.1% -0.2%, sweetener: 1% -4% of edible essence: 1.0% -1.5%, poloxamer 407: 1% -5%, cetylpyridinium chloride: 0.01% -0.2% and disodium EDTA: 0.1 to 1 percent.
2. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the Galla Turcica is processed by cleaning, sun drying and mashing.
3. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the edible essence is water-soluble essence.
4. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the ratio of glycerol to propylene glycol is 1: 1.
5. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the humectant is propylene glycol.
6. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the surfactant is sodium lauroyl sarcosinate.
7. The long lasting breath freshening bacteriostatic oral care product of claim 1 wherein: the sweetener is one or more of xylitol, saccharin sodium and acesulfame potassium.
8. A preparation method of a long-lasting fresh antibacterial oral care product is characterized by comprising the following steps: the method comprises the following steps:
s1, preparing a solution I: weighing xylitol, orange fruit extract, edible essence, sodium lauroyl sarcosinate, cetylpyridinium chloride and EDTA disodium according to the formula proportion, adding into partial water, heating and stirring until completely dissolving;
s2, preparing a solution II: weighing glycerol and propylene glycol according to the formula proportion, adding the glycerol and the propylene glycol together, uniformly mixing, adding the poloxamer 407, and uniformly mixing;
s3, preparing a solution III: weighing Galla Turcica according to formula ratio, adding into part of water, stirring to dissolve completely;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 30 minutes, adding the solution III, and continuing stirring for 10 minutes;
s5, filling: and (4) standing the mixed solution obtained in the step (4) for more than 12 hours, and then filling.
CN202010325224.5A 2020-04-23 2020-04-23 Oral care product capable of lasting freshness and bacteriostasis and preparation method thereof Pending CN111603418A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113842336A (en) * 2021-10-29 2021-12-28 重庆登康口腔护理用品股份有限公司 Solid mouthwash and preparation method thereof

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CN105997615A (en) * 2016-05-16 2016-10-12 上海儿童营养中心有限公司 Natural and edible children's mouthwash and preparation method thereof
CN106361642A (en) * 2016-10-26 2017-02-01 济川药业集团有限公司 Pudilan mouth wash and preparation process thereof
CN107714530A (en) * 2017-09-26 2018-02-23 西安罗格斯生物科技有限公司 It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray
CN110897953A (en) * 2019-12-09 2020-03-24 南通优护优家卫生用品有限公司 Breath freshener containing plant extract for relieving oral odor

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Publication number Priority date Publication date Assignee Title
CN102670458A (en) * 2012-06-06 2012-09-19 广州中汉口腔用品有限公司 Oral care solution and preparation process thereof
CN105997615A (en) * 2016-05-16 2016-10-12 上海儿童营养中心有限公司 Natural and edible children's mouthwash and preparation method thereof
CN106361642A (en) * 2016-10-26 2017-02-01 济川药业集团有限公司 Pudilan mouth wash and preparation process thereof
CN107714530A (en) * 2017-09-26 2018-02-23 西安罗格斯生物科技有限公司 It is a kind of to be used to remove removing abnormal flavor in oral cavity, antibacterial, fresh breath oral hygiene spray
CN110897953A (en) * 2019-12-09 2020-03-24 南通优护优家卫生用品有限公司 Breath freshener containing plant extract for relieving oral odor

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113842336A (en) * 2021-10-29 2021-12-28 重庆登康口腔护理用品股份有限公司 Solid mouthwash and preparation method thereof

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