CN103768435A - Breath-freshening type tobacco oral cavity spray and preparation method thereof - Google Patents

Abstract

The invention discloses a breath-freshening type tobacco oral cavity spray which comprises the following materials in percentage by weight: 0.12-4.2 percent of Chinese herb extract, 5-30 percent of tobacco extract, 1-10 percent of tobacco flavor and other auxiliary materials. The Chinese herb extract comprises agastache rugosus, radix ophiopogonis, radix rehmanniae preparata, radix angelicae, angelica sinensis, lophatherum gracile and clove which are homologous in medicines and foods, can comprise green tea, mentha haplocalyx, liquorice root, pericarpium citri reticulatae viride, scutellaria baicalensis and folium ginkgo, and can comprise smoked plum, feverfew, dandelion, moutan bark, eupatorium, momordica grosvenori and honeysuckle. By using the oral cavity spray disclosed by the invention, a user can obtain a satisfaction equal to a feel when a conventional cigarette is smoked, is beneficial to the absorption of breath-freshening active ingredients in the Chinese herb extract, is reasonable in compatibility, easy to manufacture, convenient to carry, and safe in use, can be used as a temporary substitute of the conventional cigarette in a smoke-free occasion, and can also be used as an ideal smoke-free tobacco in daily life of a cigarette consumer.

Description

A kind of fresh breath type Nicotiana tabacum L. mouth sprays and preparation method thereof

Technical field

The present invention relates to technical field of tobacco.More specifically, relate to a kind of fresh breath type Nicotiana tabacum L. mouth sprays and preparation method thereof.

Background technology

After the traditional cigarette of circulation burning in the market, can produce gas phase and the mutually two-part aerosol of grain.Gas phase part accounts for 92% of whole flue gas quality, and grain mutually part accounts for 8%, and some compositions in this two parts aerosol pollute the environment, and in addition, the stub after smoking also exists the possibility of initiation fire.

Along with the step of international Tobacco Control campaign is more accelerated, to smoking, the restriction of smoking is further strict especially in public places in national governments, and has formed gradually social consensus.Under increasingly strict Tobacco Control environment, new non-traditional tobacco product may be selected by Partial Tobacco consumer, and this variation tendency is day by day clear.Show according to statistical data in 2011, when worldwide Medicated cigarette volume of production and marketing declines to some extent, other types tobacco product presents rapid growth trend, it is estimated, within 2011, the world's non-traditional tobacco product market sale total value is about 60,000,000,000 dollars, wherein smoke-free tobacco product is about 16,000,000,000 dollars, becomes one the rising forces on World tobacco market.Therefore, further research and develop Novel smokeless gas Nicotiana tabacum L. and seem particularly necessary.

Halitosis refers to swallow as Bi ﹑ Bi Dou ﹑ from oral cavity or other are full of the cavity of air, the uncomfortable taste giving out, it is to affect people to carry out social communication and cause one of reason of mental maladjustment, approximately has 10%～65% people to be subject to the puzzlement of halitosis.Chinese medicine is the treasure of the Chinese nation, is bringing into play very important effect aspect health-care body-nourishing, control and prevention of disease.The traditional Chinese medical science thinks, halitosis is many by due to lung, spleen, stomach accumulated heat or accumulation of food in the stomach and intes tine due to indigestion, and the long-term alluvial of these things in vivo row is not gone out and just become toxin.The formation of halitosis is formed by health toxin long-term accumulated mostly, therefore by fundamentally counteract oral malodour of traditional Chinese medical science medicament conditioning health, can't be anxious for success with some the intestines and stomach is stimulated to larger medicine.

As can be seen here, often use and can not play prevention or the auxiliary health-care effect that improves the malaise symptoms such as halitosis take treatment disease as the fresh breath type mouth sprays of object.The report that there is not yet at present this type of fresh breath type Nicotiana tabacum L. mouth sprays formula both at home and abroad, therefore, need to provide a kind of fresh breath type Nicotiana tabacum L. mouth sprays and preparation method thereof.

Summary of the invention

First technical problem that the present invention will solve is to provide a kind of fresh breath type Nicotiana tabacum L. mouth sprays, and this mouth sprays is provided except providing user to be equal to by second effect also the gratification of traditional cigarette with fresh breath.

Second technical problem that the present invention will solve is to provide a kind of preparation method of fresh breath type Nicotiana tabacum L. mouth sprays, and the method preparation technology is simple, and suitability for industrialized is produced.

For solving above-mentioned first technical problem, the present invention adopts following technical proposals:

A kind of fresh breath type Nicotiana tabacum L. mouth sprays, comprises following material, counts: 0.12%-4.2% Chinese herbal medicine extract, 5%～30% tobacco extract, 1%～10% flavouring essence for tobacco by mass fraction; All the other are auxiliary material.

Preferably, described Chinese herbal medicine extract has at least 3 kinds of compound modes: comprise (1) 0.02～0.6% Herba Pogostemonis extract, 0.02～0.6% Radix Ophiopogonis extract, 0.02～0.6% Radix Rehmanniae Preparata extract, 0.02～0.6% Radix Angelicae Dahuricae extract, 0.02～0.6% Radix Angelicae Sinensis extract, 0.02～0.6% Herba Lophatheri extract and 0.02～0.6% Flos Caryophylli extract; Or

(2) 0.02～0.6% green tea extracts, 0.02～0.6% Folium Menthae extract, 0.02～0.6% Radix Glycyrrhizae extract, 0.02～0.6% Pericarpium Citri Reticulatae Viride extract, 0.02～0.6% Radix Scutellariae extract and 0.02～0.6% Folium Ginkgo extract; Or

(3) 0.02～0.6% Fructus Mume extract, 0.02～0.6% Flos Chrysanthemi extract, 0.02～0.6% Herba Taraxaci extract, 0.02～0.6% Cortex Moutan extract, 0.02～0.6% Herba Eupatorii extract, 0.02～0.6% Fructus Momordicae extract and 0.02～0.6% Flos Lonicerae extract.

Wherein, active component in said herbal medicine extract, take green tea as example, the tea polyphenols in green tea, catechin, chlorophyll, caffeine, aminoacid, vitamins and other nutritious components is exactly its active active component, the active component that these are natural, has special-effect to anti-aging, anti-cancer, anticancer, sterilization, antiinflammatory etc.

Described Chinese herbal medicine extract can directly be bought acquisition by market, also can extract voluntarily.While extraction voluntarily, can get indescribably by each Chinese medicine, finally mix, also can once extract the mixture of each Chinese medicine.

Preferably, described Chinese herbal medicine extract extracting method is as follows:

By each raw material of Chinese medicine mix homogeneously, in 70 ℃～75 ℃ pure water, flood, solid-to-liquid ratio is 1:10～15, and its filtrate is filtered and got to ultrasonic extraction after extracting 1～3h, filtering residue adds the water continuation supersound extraction 1～3h of 8～9 multiple doses to filter and get its filtrate again, merges twice filtrate; Filtrate is added and in Rotary Evaporators, is concentrated into 1/3 of filtrate volume～2/3 o'clock and stops concentrating, and cooling concentration liquid, obtains Chinese herbal medicine crude extract; Centrifugal Chinese herbal medicine crude extract, gets supernatant, obtains Chinese herbal medicine extract.

That described Chinese herbal medicine is selected is dry, free from insect pests, without going rotten, the Chinese herbal medicine of free from extraneous odour, after pulverizer is pulverized, extract.

Preferably, the pH value of described Nicotiana tabacum L. mouth sprays is 7～9; More preferably, the pH value of described Nicotiana tabacum L. mouth sprays is 9.Nicotine is one of main active in tobacco extract, and nicotine enters human circulation from buccal absorption and depends on the pH of saliva, blood plasma and the acid-base balance of nicotine.The acid-base balance of nicotine is about pKa=7.8 at 37 ℃.The pH that supposes saliva is 6.8, and only approximately 10% nicotine will be uncharged alkali form.Therefore,, in order to promote nicotine to absorb take free alkali form (its as main by the form of mucosa absorption), must increase the pH of saliva.Be 9.0 o'clock at pH, the nicotine more than 90% will be the free alkali form easily absorbing.

Preferably, described tobacco extract is that nicotine content is the material that 2.2～2.3% Nicotiana tabacum L. extracts, and comprises flue-cured tobacco extract, air-curing of tobacco leaves extract or shines one or more kinds of mixture in tobacco extract; Described air-curing of tobacco leaves comprises burley tobaccos, Maryland and wrapper cigarette; Described suncured tabacco comprises Turkish tobaccos, shines red cigarette, shines tobacco and Nicotiniana rustica.Active component in above-mentioned tobacco extract is as main tobacco flavor material (benzyl alcohol, phytol, west uncle's three enediols, 3-methyl-2-butene aldehyde, benzaldehyde, solanone, Megastigmatrienone, dihydroactinidiolide, methyl hexadecanoate, ethyl palmitate, neophytadiene, pyridine etc.) and other bioactive substance, as alkaloid, Salanesol, protein, aminoacid and saccharide etc. take alcohol, aldehyde, ketone, ester, hydro carbons, heterocyclic.Provide user to be equal to suck the gratification of traditional cigarette.

Preferably, described tobacco extract extracting method is as follows:

(1) preparation of tobacco extract: the tobacco material that composite nicotine content is 2.2～2.3%; Take above-mentioned tobacco material, add 75～80% alcohol reflux, solid-to-liquid ratio is 1:10～1:15, filters and get its filtrate after reflux, extract, 1～2h, and water-bath concentrated filtrate at 60 ℃, obtains tobacco extract; (2) setting different solvents system by countercurrent chromatography instrument separates tobacco extract; (3) determine fraction appearance time; (4) Fractional Collections effective active composition, obtains tobacco extract.

Preferably; described flavouring essence for tobacco comprises dorinone, β-damascone, 2; 6; 6-trimethyl-2-cyclohexene-1; 4-diketone, 2-hydroxyl-3; 5; 5-trimethyl-2-cyclonene, geranyl acetone, alpha, beta-lonone, furfural, 5 methyl furfural, benzaldehyde, hyacinthin, benzyl alcohol, Palmic acid, isovaleric acid, 2 methyl valeric acid, acetic acid, phenylacetic acid, dihydroactinidiolide, dimethyl succinate, indole, pyridine, 3-acetylpyridine, 3-ethylpyridine, 2-methylpyrazine and 2; 3,5-trimethylpyrazine each 2～20%.First by distill-GC/MS of head space, dissimilar flavouring essence for tobacco is carried out qualitative and quantitative analysis or collects flue-cured tobacco total particulate matter in mainstream smoke with cambridge filter, adopt GC/MS to carry out qualitative and quantitative analysis to the fragrance matter of main flume, and then tentatively draft the kind of the cigarette raw material with Nicotiana tabacum L. note, adjust the adding proportion of different material, through cigarette, fragrant Shi Fanfu debates perfume (or spice), determines cigarette kind and the adding proportion of raw material with Nicotiana tabacum L. note.And itself and Chinese medicine extract, tobacco extract, antiseptic, sweeting agent, pH adjusting agent are carried out composite, obtain fresh breath Nicotiana tabacum L. mouth sprays formula.Make user enjoy olfactory sensation, sense of taste gratification.

Preferably, described auxiliary material comprise antiseptic, pH adjusting agent, sweeting agent and solvent.

Preferably, described antiseptic is benzoic acid and sodium benzoate, propanoic acid, propionic acid sodium salt, propanoic acid calcium salt, p-Hydroxybenzoate and sodium salt thereof, Sodium Methyl Hydroxybenzoate, any one in ethylparaben and sodium salt thereof, sorbic acid and potassium salt thereof, potassium metabisulfite, sodium pyrosulfite, sodium sulfite, sodium sulfite, Hydros; The consumption of antiseptic is according to the regulation of GB2760-2011 " food additive use standard ".

Described pH adjusting agent is any one in citric acid, sorbic acid, malic acid, sodium bicarbonate, sodium hydrogen phosphate;

Described sweeting agent is one or more synthetic sugar or natural sugar; Be suitable as any type of saccharide of sweeting agent.

Described solvent is the mixture of pure water or pure water and edible glycerol.The object that the present invention adds edible glycerol be only used to dissolve some not/be insoluble in the flavouring essence for tobacco of water, its consumption can add according to those skilled in the art's experience.

For solving above-mentioned second technical problem, the present invention adopts following technical proposals:

A preparation method for fresh breath type Nicotiana tabacum L. mouth sprays, comprises following preparation process:

(1) Chinese herbal medicine extract is dissolved, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is dissolved, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, auxiliary material, stir, with pH adjusting agent adjusting goods pH value, then fill, in spraying bottle, is made finished product.

Preferably, comprise following preparation process:

(1) Chinese herbal medicine extract is dissolved, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is added edible glycerol dissolve, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, other auxiliary material, pure water is quantitative, stirs, and goods are adjusted to suitable pH value by pH adjusting agent, and then fill, in spraying bottle, is made finished product.

Beneficial effect of the present invention is as follows:

(1) spray environmental protection of the present invention, smokeless, second effect also the gratification of traditional cigarette with fresh breath is provided except providing user to be equal to.

(2) the present invention had both been applicable to male, had also been applicable to women, and user employing does not have medicine association but the means relevant to life just can be enjoyed fresh breath effect of medicinal herb components;

(3) impact and the harm of second hand smoking to non-smokers and tobacco consumption person self that when use is of the present invention, can avoid traditional cigarette to burn on environment;

(4) flavouring essence for tobacco adding can provide cigarette consumption person's olfactory sensation, sense of taste gratification;

(5) compatibility of the present invention is reasonable, is easy to manufacture, and the goods of spray-type are easy to carry, uses health.In a word, both can be used as the interim succedaneum of ban on opium-smoking and the opium trade place traditional cigarette according to the mouth sprays goods of this formula development, also can become a kind of desirable novel environment friendly health smoke-free tobacco product in smoker's daily life.

The specific embodiment

In order to be illustrated more clearly in the present invention, below in conjunction with preferred embodiment, the present invention is described further.It will be appreciated by those skilled in the art that specifically described content is illustrative and nonrestrictive below, should not limit the scope of the invention with this.

Embodiment 1

20g spray goods

(1) by adding 10g dissolved in purified water after Herba Pogostemonis, Radix Ophiopogonis, Radix Rehmanniae Preparata, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Herba Lophatheri and Flos Caryophylli seven taste Chinese herbal medicine extract mix homogeneously, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is mixed in proportion, add proper amount of edible glycerol to dissolve, obtain mixed solution B, (when use, taking as requested again exact mass) for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, ethylparaben (being commonly called as Nepal's ethyl ester), sucrose, then quantitatively arrive 20g with pure water, stir, goods pH value is adjusted to 7 by pH adjusting agent, then fill, in spraying bottle, is made finished product.

Result of use is evaluated: the mouth sprays goods of organizing three Nicotiana tabacum L. evaluation and analysis librarian use embodiment of the present invention 1, experimental result shows, in the time that the personnel that smoke panel test produce smoking cigarette desire, disposable spray sucks these goods of 0.4g, after average 2min, smoking cigarette desire disappears, and can on average continue 71min without smoking cigarette desire.

Embodiment 2

50g spray goods

The present embodiment preparation method is similar to embodiment 1, and raw material changes to some extent and then makes the content of active component in the fragrant and tobacco extract of the Nicotiana tabacum L. of goods different.

(1) by adding 30g dissolved in purified water after green tea, Herba Menthae, Radix Glycyrrhizae, Pericarpium Citri Reticulatae Viride, Radix Scutellariae and Folium Ginkgo Six-element Chinese herbal medicine extract mix homogeneously, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is mixed in proportion, add proper amount of edible glycerol to dissolve, obtain mixed solution B, (when use, taking as requested again exact mass) for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, sorbic acid, sucrose, then quantitatively arrive 50g with pure water, stir, goods pH value is adjusted to 8.9 by pH adjusting agent, then fill, in spraying bottle, is made finished product.

Result of use is evaluated: the mouth sprays goods of organizing three Nicotiana tabacum L. evaluation and analysis librarian use embodiment of the present invention 2, experimental result shows, in the time that the personnel that smoke panel test produce smoking cigarette desire, disposable spray sucks these goods of 0.4g, after average 2min, smoking cigarette desire disappears, and can on average continue 60min without smoking cigarette desire.

Embodiment 3

100g spray goods

(1) by adding 65g dissolved in purified water after Fructus Mume, Flos Chrysanthemi, Herba Taraxaci, Flos Lonicerae, Cortex Moutan, Herba Eupatorii and Fructus Momordicae seven taste Chinese herbal medicine extract mix homogeneously, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is added edible glycerol dissolve, obtain mixed solution B, (when use, taking as requested again exact mass) for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, Nepal's ethyl ester, sucrose, then quantitatively arrive 100g with pure water, stir, goods pH value is adjusted to 9 by pH adjusting agent, then fill, in spraying bottle, is made finished product.

Result of use is evaluated: the mouth sprays goods of organizing three Nicotiana tabacum L. evaluation and analysis librarian use embodiment of the present invention 3, experimental result shows, in the time that the personnel that smoke panel test produce smoking cigarette desire, disposable spray sucks these goods of 0.4g, after average 2min, smoking cigarette desire disappears, and can on average continue 53min without smoking cigarette desire.

Embodiment 4

(1) 0.06% Herba Pogostemonis extract, 0.06% Radix Ophiopogonis extract, 0.06% Radix Rehmanniae Preparata extract, 0.06% Radix Angelicae Dahuricae extract, 0.06% Radix Angelicae Sinensis extract, 0.06% Herba Lophatheri extract and 0.06% Flos Caryophylli extract are dissolved, obtain mixed solution A, for subsequent use;

(2) 1% flavouring essence for tobacco is dissolved, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, auxiliary material, stir, with pH adjusting agent adjusting goods pH value, then fill, in spraying bottle, is made finished product.

Embodiment 5

(1) 0.2% Herba Pogostemonis extract, 0.2% Radix Ophiopogonis extract, 0.2% Radix Rehmanniae Preparata extract, 0.2% Radix Angelicae Dahuricae extract, 0.2% Radix Angelicae Sinensis extract, 0.2% Herba Lophatheri extract and 0.2% Flos Caryophylli extract are dissolved, obtain mixed solution A, for subsequent use;

(2) 10% flavouring essence for tobacco is dissolved, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, auxiliary material, stir, regulating goods pH value by pH adjusting agent is 8, and then fill, in spraying bottle, is made finished product.The antiseptic of described auxiliary material is sodium sulfite, and sweeting agent is natural sugar; PH adjusting agent is citric acid.

Embodiment 6-17

Repeat embodiment 5, its difference is only, described antiseptic is respectively propanoic acid, propionic acid sodium salt, propanoic acid calcium salt, p-Hydroxybenzoate and sodium salt thereof, Sodium Methyl Hydroxybenzoate, ethylparaben, P-hydroxybenzoic acid sodium salt, sorbic acid and potassium salt, potassium metabisulfite, sodium pyrosulfite, sodium sulfite or Hydros.

Embodiment 18-20

Repeat embodiment 5, its difference is only, described pH adjusting agent is malic acid, sodium bicarbonate, sodium hydrogen phosphate.

Obviously; the above embodiment of the present invention is only for example of the present invention is clearly described; and be not the restriction to embodiments of the present invention; for those of ordinary skill in the field; can also make other changes in different forms on the basis of the above description; here cannot give all embodiments exhaustively, everyly belong to apparent variation or the still row in protection scope of the present invention of variation that technical scheme of the present invention extends out.

Claims (9)

1. a fresh breath type Nicotiana tabacum L. mouth sprays, is characterized in that, comprises following material, counts by mass fraction: all the other are auxiliary material for 0.12%～4.2% Chinese herbal medicine extract, 5%～30% tobacco extract, 1%～10% flavouring essence for tobacco.

2. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, it is characterized in that, described Chinese herbal medicine extract comprises (1) 0.02～0.6% Herba Pogostemonis extract, 0.02～0.6% Radix Ophiopogonis extract, 0.02～0.6% Radix Rehmanniae Preparata extract, 0.02～0.6% Radix Angelicae Dahuricae extract, 0.02～0.6% Radix Angelicae Sinensis extract, 0.02～0.6% Herba Lophatheri extract and 0.02～0.6% Flos Caryophylli extract; Or

(2) 0.02～0.6% green tea extracts, 0.02～0.6% Folium Menthae extract, 0.02～0.6% Radix Glycyrrhizae extract, 0.02～0.6% Pericarpium Citri Reticulatae Viride extract, 0.02～0.6% Radix Scutellariae extract and 0.02～0.6% Folium Ginkgo extract; Or

(3) 0.02～0.6% Fructus Mume extract, 0.02～0.6% Flos Chrysanthemi extract, 0.02～0.6% Herba Taraxaci extract, 0.02～0.6% Cortex Moutan extract, 0.02～0.6% Herba Eupatorii extract, 0.02～0.6% Fructus Momordicae extract and 0.02～0.6% Flos Lonicerae extract.

3. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, is characterized in that, described Nicotiana tabacum L. mouth sprays pH value is 7～9; More preferably, the pH value of described Nicotiana tabacum L. mouth sprays is 9.

4. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, is characterized in that, described tobacco extract is that nicotine content is the material that 2.2～2.3% Nicotiana tabacum L. extracts; Comprise flue-cured tobacco extract, air-curing of tobacco leaves extract or shine one or more mixture in tobacco extract; Described air-curing of tobacco leaves comprises burley tobaccos, Maryland and wrapper cigarette; Described suncured tabacco comprises Turkish tobaccos, shines red cigarette, shines tobacco and Nicotiniana rustica.

5. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, is characterized in that, described tobacco extract extracting method is as follows:

(1) preparation of tobacco extract: the tobacco material that composite nicotine content is 2.2～2.3%; Take above-mentioned tobacco material, add 75～80% alcohol reflux, solid-to-liquid ratio is 1:10～1:15, filters and get its filtrate after reflux, extract, 1～2h, and water-bath concentrated filtrate at 60 ℃, obtains tobacco extract; (2) setting different solvents system by countercurrent chromatography instrument separates tobacco extract; (3) determine fraction appearance time; (4) Fractional Collections effective active composition, obtains tobacco extract.

6. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, it is characterized in that, described flavouring essence for tobacco comprises dorinone, β-damascone, 2, 6, 6-trimethyl-2-cyclohexene-1, 4-diketone, 2-hydroxyl-3, 5, 5-trimethyl-2-cyclonene, geranyl acetone, alpha, beta-lonone, bran aldehyde, 5 methyl furfural, benzaldehyde, hyacinthin, benzyl alcohol, Palmic acid, isovaleric acid, 2 methyl valeric acid, acetic acid, phenylacetic acid, dihydroactinidiolide, dimethyl succinate, indole, pyridine, 3-acetylpyridine, 3-ethylpyridine, 2-methylpyrazine and 2, 3, one or more mixture in 5-trimethylpyrazine.

7. fresh breath type Nicotiana tabacum L. mouth sprays according to claim 1, is characterized in that, described auxiliary material comprise antiseptic, sweeting agent, solvent and pH adjusting agent;

Preferably, described antiseptic is benzoic acid and sodium benzoate, propanoic acid, propionic acid sodium salt, propanoic acid calcium salt, p-Hydroxybenzoate and sodium salt thereof, Sodium Methyl Hydroxybenzoate, any one in ethylparaben and sodium salt thereof, sorbic acid and potassium salt thereof, potassium metabisulfite, sodium pyrosulfite, sodium sulfite, sodium sulfite, Hydros;

Described sweeting agent is one or more synthetic sugar or natural sugar;

Described solvent is the mixture of pure water or pure water and edible glycerol;

Described pH adjusting agent is any one in citric acid, sorbic acid, malic acid, sodium bicarbonate, sodium hydrogen phosphate.

8. the preparation method of the fresh breath type Nicotiana tabacum L. mouth sprays as described in claim 1～7, is characterized in that, comprises following preparation process:

(1) Chinese herbal medicine extract is dissolved, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is added edible glycerol dissolve, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, auxiliary material, stir, with pH adjusting agent adjusting goods pH value, then fill, in spraying bottle, is made finished product.

9. the preparation method of fresh breath type Nicotiana tabacum L. mouth sprays according to claim 8, is characterized in that, comprises the following steps:

(1) by dissolving after Chinese herbal medicine extract mix homogeneously, obtain mixed solution A, for subsequent use;

(2) flavouring essence for tobacco is added edible glycerol dissolve, obtain mixed solution B, for subsequent use;

(3) the mixed solution B of mixed solution A and exact mass is merged, add wherein tobacco extract, other auxiliary material, pure water is quantitative, stirs, and goods are adjusted to suitable pH value by pH adjusting agent, and then fill, in spraying bottle, is made finished product.