CN110448513B - Toothpaste capable of refreshing breath and nourishing gums - Google Patents
Toothpaste capable of refreshing breath and nourishing gums Download PDFInfo
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- CN110448513B CN110448513B CN201910703653.9A CN201910703653A CN110448513B CN 110448513 B CN110448513 B CN 110448513B CN 201910703653 A CN201910703653 A CN 201910703653A CN 110448513 B CN110448513 B CN 110448513B
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- 239000000606 toothpaste Substances 0.000 title claims abstract description 42
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 42
- 239000000843 powder Substances 0.000 claims abstract description 43
- 239000000463 material Substances 0.000 claims abstract description 35
- 229940067866 dandelion extract Drugs 0.000 claims abstract description 34
- 235000020691 dandelion extract Nutrition 0.000 claims abstract description 34
- 239000001845 taraxacum officinale leaf extract Substances 0.000 claims abstract description 34
- 229940094952 green tea extract Drugs 0.000 claims abstract description 33
- 235000020688 green tea extract Nutrition 0.000 claims abstract description 33
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 239000002245 particle Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 235000003599 food sweetener Nutrition 0.000 claims description 11
- 239000003906 humectant Substances 0.000 claims description 11
- 239000003755 preservative agent Substances 0.000 claims description 11
- 230000002335 preservative effect Effects 0.000 claims description 11
- 239000004094 surface-active agent Substances 0.000 claims description 11
- 239000003765 sweetening agent Substances 0.000 claims description 11
- 239000002562 thickening agent Substances 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 239000000686 essence Substances 0.000 claims description 6
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 6
- 235000013824 polyphenols Nutrition 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 5
- 239000002202 Polyethylene glycol Substances 0.000 claims description 5
- 229920002125 Sokalan® Polymers 0.000 claims description 5
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 5
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- 235000011187 glycerol Nutrition 0.000 claims description 5
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- 229950008882 polysorbate Drugs 0.000 claims description 5
- 229920000136 polysorbate Polymers 0.000 claims description 5
- 239000011347 resin Substances 0.000 claims description 5
- 229920005989 resin Polymers 0.000 claims description 5
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 5
- 235000010234 sodium benzoate Nutrition 0.000 claims description 5
- 239000004299 sodium benzoate Substances 0.000 claims description 5
- 239000000600 sorbitol Substances 0.000 claims description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 5
- 229940013618 stevioside Drugs 0.000 claims description 5
- 235000019202 steviosides Nutrition 0.000 claims description 5
- 239000000230 xanthan gum Substances 0.000 claims description 5
- 229920001285 xanthan gum Polymers 0.000 claims description 5
- 229940082509 xanthan gum Drugs 0.000 claims description 5
- 235000010493 xanthan gum Nutrition 0.000 claims description 5
- 244000269722 Thea sinensis Species 0.000 claims description 4
- 239000006072 paste Substances 0.000 claims description 4
- 235000013616 tea Nutrition 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- -1 nipagin ester Chemical class 0.000 claims description 3
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 2
- 108010011485 Aspartame Proteins 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 2
- 241000245665 Taraxacum Species 0.000 claims description 2
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims description 2
- YGCFIWIQZPHFLU-UHFFFAOYSA-N acesulfame Chemical compound CC1=CC(=O)NS(=O)(=O)O1 YGCFIWIQZPHFLU-UHFFFAOYSA-N 0.000 claims description 2
- 229960005164 acesulfame Drugs 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- 239000000605 aspartame Substances 0.000 claims description 2
- 235000010357 aspartame Nutrition 0.000 claims description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 2
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- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 238000007872 degassing Methods 0.000 claims description 2
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 claims description 2
- 230000001804 emulsifying effect Effects 0.000 claims description 2
- 238000004806 packaging method and process Methods 0.000 claims description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 2
- 229940083575 sodium dodecyl sulfate Drugs 0.000 claims description 2
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims 1
- 229930003935 flavonoid Natural products 0.000 claims 1
- 235000017173 flavonoids Nutrition 0.000 claims 1
- 150000002215 flavonoids Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 21
- 238000004140 cleaning Methods 0.000 abstract description 5
- 210000000214 mouth Anatomy 0.000 abstract description 4
- 210000004195 gingiva Anatomy 0.000 abstract description 2
- 230000000052 comparative effect Effects 0.000 description 11
- 239000000126 substance Substances 0.000 description 7
- 206010006326 Breath odour Diseases 0.000 description 4
- 208000032139 Halitosis Diseases 0.000 description 4
- 230000000740 bleeding effect Effects 0.000 description 4
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- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000551 dentifrice Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
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- 231100000957 no side effect Toxicity 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
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- 238000005498 polishing Methods 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Marine Sciences & Fisheries (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses toothpaste capable of refreshing breath and nourishing gingiva, which comprises the following raw materials in parts by weight: 1-30 parts of cuttlebone powder, 1-15 parts of apple extract, 1-15 parts of dandelion extract, 1-15 parts of green tea extract and 70-90 parts of auxiliary materials. The toothpaste combines the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract, not only can exert respective effects, but also can play a role in synergy promotion, so that the effects of cleaning oral cavity and refreshing breath are achieved, and the effects of protecting teeth and nourishing gums are also achieved.
Description
Technical Field
The invention relates to the technical field of daily necessities, in particular to toothpaste capable of refreshing breath and nourishing gums.
Background
The toothpaste is a cleaning article commonly used in daily life, is a dentifrice, is generally in a gel shape, is used for cleaning teeth, keeps the beauty and the brightness of the teeth, and has a long history. With the continuous development of science and technology, the continuous improvement and perfection of technological equipment, various types of toothpaste are developed in succession, the quality and the grade of products are continuously improved, and the existing toothpaste variety is developed into multifunctional toothpaste with complete variety, multiple functions and hundreds of brands from single clean toothpaste. The toothpaste has the functions of rubbing, removing bacterial plaque, cleaning and polishing tooth surfaces and refreshing the oral cavity, and meanwhile, the functional toothpaste also has the effects of keeping healthy teeth and nourishing gums.
Most of toothpaste in the market has the function of refreshing breath, but when gum has problems, such as redness and swelling of gum, bleeding of gum, gum atrophy and the like, plaque bacteria attached to the gum can be removed only by means of clinical scraping treatment, and the toothpaste has a very small effect.
Disclosure of Invention
The invention aims to provide toothpaste capable of refreshing breath and nourishing gums aiming at the problems that toothpaste in the prior art is lack of nourishing gums and bacteriostasis function. The technical scheme adopted for realizing the purpose of the invention is as follows:
the toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight:
1-30 parts of cuttlebone powder, 1-15 parts of apple extract, 1-15 parts of dandelion extract, 1-15 parts of green tea extract and 70-90 parts of auxiliary materials.
In the technical scheme, the toothpaste comprises the following raw materials in parts by weight: 4-16 parts of cuttlebone powder, 3-10 parts of apple extract, 2-10 parts of dandelion extract, 3-10 parts of green tea extract and 75-80 parts of auxiliary materials, more preferably 8 parts of cuttlebone powder, 6 parts of apple extract, 3 parts of dandelion extract, 5 parts of green tea extract and 78 parts of auxiliary materials.
In the technical scheme, the auxiliary materials comprise a humectant, a surfactant, a thickening agent, a sweetening agent, a preservative, sodium chloride, essence and deionized water.
In the technical scheme, the auxiliary materials comprise the following raw materials in parts by weight: 50-75 parts of humectant, 0.5-5 parts of surfactant, 0.1-5 parts of thickening agent, 0.15-3 parts of sweetening agent, 0.15-1.5 parts of preservative, 1-8 parts of sodium chloride, 0.1-1 part of essence and 20-45 parts of deionized water.
In the technical scheme, the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract are all powder with the particle size of less than 120 meshes.
In the technical scheme, the apple extract contains 10-80% of polyphenol, the green tea extract contains 10-98% of tea polyphenol, and the dandelion extract contains 4-10% of dandelion flavone.
In the technical scheme, the humectant is one or more of glycerol, propylene glycol, sorbitol and polyethylene glycol in any proportion;
the surfactant is one or more of polysorbate, sodium dodecyl sulfate and sodium dodecyl benzene sulfonate in any proportion;
the thickening agent is one or more of sodium carboxymethylcellulose, xanthan gum and carbomer resin in any proportion;
the sweetener is one or more of aspartame, acesulfame and stevioside in any proportion;
the preservative is one or two of sodium benzoate and nipagin ester.
In the technical scheme, the humectant is a mixture of sorbitol, polyethylene glycol and glycerin, the surfactant is polysorbate, the thickener is a mixture of carbomer resin and xanthan gum, the sweetener is stevioside, and the preservative is a mixture of sodium benzoate and nipagin ester.
In the technical scheme, the toothpaste is prepared by the following method:
step 1, respectively crushing cuttlebone powder, apple extract, dandelion extract and green tea extract to powder with the particle size of less than 120 meshes by using a superfine crusher (the particle size is adjusted by using a screen of the superfine crusher);
step 2, weighing and mixing the humectant, the surfactant, the thickening agent, the preservative, the sodium chloride and the deionized water in proportion, and emulsifying in a homogenizer for 5-20 minutes;
step 3, weighing the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract according to the proportion, mixing the materials obtained in the step 2, adding the mixture into a vacuum paste making machine, and grinding and mixing the materials at a high speed for 20-40 minutes;
and 4, grinding and mixing the mixture obtained in the step 3 and the sweetening agent and the essence in proportion at a high speed for 10-30 minutes in a vacuum paste making machine, degassing in vacuum to obtain the required toothpaste, and finally filling and packaging.
In another aspect of the present invention, there is also provided a use of cuttlebone powder, apple extract, dandelion extract and green tea extract in a toothpaste for synergistic effect, wherein: the weight ratio of the cuttlebone powder to the apple extract to the dandelion extract to the green tea extract to the auxiliary materials is (1-30): (1-15): (1-15): (1-15): (70-90).
Compared with the prior art, the invention has the beneficial effects that:
1. the cuttlebone powder not only rubs and cleans and polishes the tooth surface, removes dental plaque, but also has the effects of stopping bleeding and diminishing inflammation, the apple extract can nourish teeth and gum, and also has the effects of refreshing breath and eliminating halitosis, the apple polyphenol has various health-care functions, such as preventing decayed teeth, preventing hypertension and preventing anaphylactic reaction, the tea polyphenol can effectively resist oxidation, fix color, fix fragrance, eliminate halitosis and the like, and the dandelion extract has a wide antibacterial effect and can promote the immune function of a human body. The invention combines and uses four effective components of cuttlebone powder, apple extract, dandelion extract and green tea extract, not only can exert respective effects, but also can play a role in synergy promotion, thereby not only achieving the effects of cleaning oral cavity and refreshing breath, but also playing the effects of protecting teeth and nourishing gums.
2. The synergistic effect of the four effective components prolongs the efficacy time of the composition, improves the use effect, is safe and has no side effect.
3. The four effective components with the grain diameter less than 120 meshes can not only physically rub and clean the polished tooth surface and remove dental plaque, but also effectively exert the drug property.
Detailed Description
The present invention will be described in further detail with reference to specific examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In the following examples and comparative examples
The cuttlebone powder is prepared by the following method:
the method comprises the following steps of crushing purchased cuttlebone powder (pharmacy of Tianjin common people) into 120-mesh powder, 180-mesh powder, 200-mesh powder and 250-mesh powder respectively by an ultrafine pulverizer.
The apple extract is prepared by the following method:
an apple extract (Shaanxi forest Freund Natural products Co., Ltd., batch No: PG180516) purchased from outsourced was pulverized by a micronizer into 150 mesh powder, 180 mesh powder, 200 mesh powder and 325 mesh powder, respectively, in particle size.
The dandelion extract is prepared by the following method:
an externally purchased dandelion extract (Shaanxi forest Freund natural products Co., Ltd., lot: PGY181026) was pulverized by an ultrafine pulverizer into powders having particle diameters of 150 mesh, 160 mesh, 300 mesh and 325 mesh, respectively.
The green tea extract was prepared by the following method:
an outsourced green tea extract (Shaanxi forest Freund natural products Co., Ltd., lot: LC181117) was pulverized by an ultrafine pulverizer into powder having a particle size of 180 mesh, 200 mesh, 325 mesh and 400 mesh, respectively.
Example 1
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 8 parts of cuttlebone powder (with the particle size of 200 meshes), 6 parts of apple extract (with the particle size of 180 meshes), 3 parts of dandelion extract (with the particle size of 300 meshes), 5 parts of green tea extract (with the particle size of 400 meshes) and 78 parts of auxiliary materials. Wherein the total parts of the functional substances are 22 parts.
Wherein the auxiliary materials comprise the following raw materials in percentage by weight:
when the effective component is matched with the auxiliary materials of the above components (namely, the humectant is a mixture of sorbitol, polyethylene glycol and glycerol, the surfactant is polysorbate, the thickener is a mixture of carbomer resin and xanthan gum, the sweetening agent is stevioside, and the preservative is a mixture of sodium benzoate and paraben), the prepared toothpaste has the optimal effect, and the effect data table is detailed.
Example 2
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 16 parts of cuttlebone powder (with the grain diameter of 250 meshes), 10 parts of apple extract (with the grain diameter of 200 meshes), 10 parts of dandelion extract (with the grain diameter of 325 meshes), 10 parts of green tea extract (with the grain diameter of 200 meshes) and 75 parts of auxiliary materials with the same components and content as in example 1.
Example 3
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 30 parts of cuttlebone powder (with the grain diameter of 200 meshes), 15 parts of apple extract (with the grain diameter of 325 meshes), 15 parts of dandelion extract (with the grain diameter of 160 meshes), 15 parts of green tea extract (with the grain diameter of 325 meshes) and 70 parts of auxiliary materials with the same components and content as in example 1.
Blank comparative example (placebo)
Comparative example 1 (Endoconcha Sepiae powder single prescription)
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 22 parts of cuttlebone powder (with the particle size of 200 meshes) and 78 parts of auxiliary materials, wherein the auxiliary materials have the same components and content as those in the example 1.
COMPARATIVE EXAMPLE 2 apple extract Single recipe)
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 22 parts of apple extract (with the particle size of 180 meshes) and 78 parts of auxiliary materials, wherein the auxiliary materials have the same components and content as those in example 1. Wherein the total parts of the functional substances are 22 parts.
COMPARATIVE EXAMPLE 3 Dandelion extract Single recipe
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 22 parts of dandelion extract (particle size of 300 meshes) and 78 parts of auxiliary materials, wherein the auxiliary materials have the same components and content as those in example 1. Wherein the total parts of the functional substances are 22 parts.
COMPARATIVE EXAMPLE 4 Green tea extract list
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 22 parts of green tea extract (with the particle size of 400 meshes) and 78 parts of auxiliary materials, wherein the auxiliary materials have the same components and content as those in example 1. Wherein the total parts of the functional substances are 22 parts.
Comparative example 5
In the embodiment, cuttlebone powder is not contained, and 8 parts of apple extract are correspondingly added.
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 14 parts of apple extract (with the grain diameter of 180 meshes), 3 parts of dandelion extract (with the grain diameter of 300 meshes), 5 parts of green tea extract (with the grain diameter of 400 meshes) and 78 parts of auxiliary materials, wherein the components and the content of the auxiliary materials are the same as those in example 3. Wherein the total parts of the functional substances are 22 parts.
Comparative example 6
In this example, no cuttlebone powder was contained, and 8 parts of dandelion extract were added.
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 6 parts of apple extract (with the grain diameter of 180 meshes), 11 parts of dandelion extract (with the grain diameter of 300 meshes), 5 parts of green tea extract (with the grain diameter of 400 meshes) and 78 parts of auxiliary materials, wherein the components and the content of the auxiliary materials are the same as those in example 3. Wherein the total parts of the functional substances are 22 parts.
Comparative example 7
In the embodiment, cuttlebone powder is not contained, and 8 parts of green tea extract are correspondingly added.
The toothpaste capable of refreshing breath and nourishing gums comprises the following raw materials in parts by weight: 6 parts of apple extract (with the grain diameter of 180 meshes), 11 parts of dandelion extract (with the grain diameter of 300 meshes), 13 parts of green tea extract (with the grain diameter of 400 meshes) and 78 parts of auxiliary materials, wherein the components and the content of the auxiliary materials are the same as those in example 3. Wherein the total parts of the functional substances are 22 parts.
The trial effect experiments are carried out on people who have obvious oral problems such as frequent smoking, drinking tea and the like in life and people who have red and swollen gums, habitual bleeding, gingival atrophy and habitual halitosis. The experiment was carried out in groups of 20 persons each, each being used 1 time each day, morning and evening. The experimental data of the improvement of oral cavity problems by each group of products after 1 month of follow-up feedback are shown in table 1. The effect in table 1 clearly means: the gum is changed from deep red to healthy pink, the swelling degree is obviously reduced or disappeared, the bleeding condition of the gum is obviously reduced or disappeared, and the habitual halitosis is disappeared or is occasionally seen.
Effect data Table 1
Similar to comparative examples 5 to 7, removing one of the effects (any one of apple extract, dandelion extract and green tea extract) and then adding the weight part of the effect to the other three effects, the average effective rate of the comparative examples was 70 to 85%, which is much lower than that of examples 1 to 3 of the present invention.
As can be seen from the table 1, the effect of the four effective components of the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract is single or when one component is lacked, the synergistic effect of the four effective components is not generated, and the gingival problem can be effectively relieved under the combined action of the four effective components, so that the effect of nourishing the gingiva is achieved.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (8)
1. The toothpaste capable of refreshing breath and nourishing gums is characterized by comprising the following raw materials in parts by weight:
1-30 parts of cuttlebone powder, 1-15 parts of apple extract, 1-15 parts of dandelion extract, 1-15 parts of green tea extract and 70-90 parts of auxiliary materials;
the auxiliary materials comprise a humectant, a surfactant, a thickening agent, a sweetening agent, a preservative, sodium chloride, essence and deionized water;
the toothpaste is prepared by the following method:
step 1, respectively crushing cuttlebone powder, apple extract, dandelion extract and green tea extract to powder with the particle size of less than 120 meshes by using a superfine crusher;
step 2, weighing and mixing the humectant, the surfactant, the thickening agent, the preservative, the sodium chloride and the deionized water in proportion, and emulsifying in a homogenizer for 5-20 minutes;
step 3, weighing the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract according to the proportion, mixing the materials obtained in the step 2, adding the mixture into a vacuum paste making machine, and grinding and mixing the materials at a high speed for 20-40 minutes;
and 4, grinding and mixing the mixture obtained in the step 3 and the sweetening agent and the essence in proportion at a high speed for 10-30 minutes in a vacuum paste making machine, degassing in vacuum to obtain the required toothpaste, and finally filling and packaging.
2. The breath freshening, gum nourishing toothpaste of claim 1 comprising the following raw materials in parts by weight: 4-16 parts of cuttlebone powder, 3-10 parts of apple extract, 2-10 parts of dandelion extract, 3-10 parts of green tea extract and 75-80 parts of auxiliary materials.
3. The breath freshening and gum nourishing toothpaste as claimed in claim 2, wherein the cuttlebone powder comprises 8 parts, the apple extract comprises 6 parts, the dandelion extract comprises 3 parts, the green tea extract comprises 5 parts, and the auxiliary material comprises 78 parts.
4. The breath freshening and gingival nourishing toothpaste as claimed in claim 3, wherein the adjuvant comprises the following raw materials in parts by weight: 50-75 parts of humectant, 0.5-5 parts of surfactant, 0.1-5 parts of thickening agent, 0.15-3 parts of sweetening agent, 0.15-1.5 parts of preservative, 1-8 parts of sodium chloride, 0.1-1 part of essence and 20-45 parts of deionized water.
5. The breath freshening and gum nourishing toothpaste of claim 1 wherein the apple extract comprises from 10% to 80% polyphenols, the green tea extract comprises from 10% to 98% tea polyphenols, and the dandelion extract comprises from 4% to 10% dandelion flavonoids.
6. The breath freshening, gum nourishing toothpaste as recited in claim 4 wherein said humectant is one or more of glycerin, propylene glycol, sorbitol, polyethylene glycol in any proportion;
the surfactant is one or more of polysorbate, sodium dodecyl sulfate and sodium dodecyl benzene sulfonate in any proportion;
the thickening agent is one or more of sodium carboxymethylcellulose, xanthan gum and carbomer resin in any proportion;
the sweetener is one or more of aspartame, acesulfame and stevioside in any proportion;
the preservative is one or two of sodium benzoate and nipagin ester.
7. The breath freshening, gingival nourishing toothpaste of claim 6 wherein the humectant is a mixture of sorbitol, polyethylene glycol and glycerin, the surfactant is polysorbate, the thickener is a mixture of carbomer resin and xanthan gum, the sweetener is stevioside, and the preservative is a mixture of sodium benzoate and paraben.
8. The application of the cuttlebone powder, the apple extract, the dandelion extract and the green tea extract in preparing the toothpaste is characterized in that the mass ratio of the cuttlebone powder, the apple extract, the dandelion extract, the green tea extract and the auxiliary materials is (1-30): (1-15): (1-15): (1-15): (70-90).
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