CN107595697A - It is a kind of to remove removing abnormal flavor in oral cavity, antibacterial and anti-caries oral hygiene spray for women and children - Google Patents

It is a kind of to remove removing abnormal flavor in oral cavity, antibacterial and anti-caries oral hygiene spray for women and children Download PDF

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Publication number
CN107595697A
CN107595697A CN201710882869.7A CN201710882869A CN107595697A CN 107595697 A CN107595697 A CN 107595697A CN 201710882869 A CN201710882869 A CN 201710882869A CN 107595697 A CN107595697 A CN 107595697A
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China
Prior art keywords
oral hygiene
spray
oral
oral cavity
antibacterial
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Pending
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CN201710882869.7A
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Chinese (zh)
Inventor
谢知芳
常雪妮
蒋丽娟
薛建龙
冯立雄
纳泽·米尔
迈克尔·里奥尼德斯·崎肯德思
基特·彦姆
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Qiaokang Biotech Guangdong Co Ltd
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Xi'an Rogers Biological Science And Technology Co Ltd
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Priority to CN201710882869.7A priority Critical patent/CN107595697A/en
Publication of CN107595697A publication Critical patent/CN107595697A/en
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Abstract

Removing abnormal flavor in oral cavity, antibacterial, anti-caries oral hygiene spray are removed suitable for women and children the invention provides a kind of, belongs to daily chemicals field.According to weight meter, the spray includes 0.00005%~0.0005% and goes removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~10% natural plant essential oils, 0.001%~0.02% surfactant, 0.05%~0.3% flavouring, 0.001%~0.005% to prevent carious tooth and bacterial plaque material and 0.000001%~0.0001% food coloring, and surplus is deionized water.The spray can Efficient antibacterial, fresh breath, anti-inflammatory it is calm, realize the total care to oral cavity, the generation of mouth disease can be reduced, composition is safe, is especially suitable for women and children use.

Description

It is a kind of to go to removing abnormal flavor in oral cavity, antibacterial and anti-caries oral cavity for women and children Hygienic spray
Technical field
The invention belongs to daily chemicals field, it is more particularly to a kind of suitable for women and children go removing abnormal flavor in oral cavity, Antibacterial, anti-caries oral hygiene sprays.
Background technology
With the development of the society, people also increasingly improve for the health care demand in oral cavity.But at the same time, China oral cavity disease The illness rate of disease is high, scope is wide, and the permanent teeth caries prevalence rate being grown up according to statistics is 49.88%, children's Primary Caries rate 80%, periodontosis Illness rate about 90%, oral health, the importance of teeth caring are increasingly valued by the people.The health care in oral cavity includes preventing dental caries Tooth, suppress oral bacteria and remove removing abnormal flavor in oral cavity.The main reason of these problems is that bacterium, host and three big factor of diet are mutual Effect is caused a disease, and in these three factors headed by the influence of bacterium.Oral bacteria fermented foodstuff residue, produce sour and various sulphur Compound, on the one hand corrode tooth glaze paint and form bacterial plaque, on the one hand cause halitosis, have a strong impact on people's quality of life, especially Ms and children.The influence of oral cavity anaerobium is eliminated, carious tooth is prevented, removes removing abnormal flavor in oral cavity, depends merely on the brush of daily finite number of time Tooth is inadequate, important means of the gargle with the characteristics of its is convenient, efficient, raciness as oral care.But current market The mouth sprays class product of upper sale, most effect is single and is mostly treatment periodontal disease, and prevention and the product of health are Number is few, specifically for the even more few of women and children.Therefore a kind of removal mouth suitable for women and children is developed Cavity foreign flavor, antibacterial, anti-caries oral hygiene spray are highly significant.
Chlorine dioxide antiseptic power is strong, has a broad antifungal spectrum, has killing action to bacterium, virus, fungi and gemma etc., and act on Rapidly, bactericidal effect is influenceed small by environmental condition (temperature, pH value, organic matter), nontoxic, non-stimulated, environmentally safe, in Europe Man of the U.S. is used in many oral care products, for tooth whitening and health care, pre- anti-caries and periodontal disease, especially uses In the preventing and treating of halitosis.Experimental results demonstrate chlorine dioxide can kill oral cavity anaerobium, halitosis, oral health effect are fundamentally treated Fruit is significantly better than other products.Rosa Damascana fragrant, after entering brain via smell, there is sedation effect, contact has anti-inflammatory Sterilization, pressor effect, are welcome by everybody deeply on cosmetics.And chlorine dioxide and Rosa Damascana are used simultaneously in China It is few in the product of oral care.
The content of the invention
It is an object of the invention to provide a kind of removing abnormal flavor in oral cavity, antibacterial, anti-caries is removed suitable for women and children Oral hygiene spray, its can Efficient antibacterial, fresh breath, anti-inflammatory it is calm, realize the total care to oral cavity, oral cavity can be reduced The generation of disease, composition is safe, is especially suitable for women and children use.
The present invention is to be achieved through the following technical solutions:
It is a kind of to remove removing abnormal flavor in oral cavity, antibacterial, anti-caries oral hygiene spray suitable for women and children, according to weight Meter, the spray include 0.00005%~0.0005% and remove removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~10% natural plants Essential oil, 0.001%~0.02% surfactant, 0.05%~0.3% flavouring, 0.001%~0.005% prevent Carious tooth and bacterial plaque material and 0.000001%~0.0001% food coloring, surplus are deionized water.
Preferably, the described removing abnormal flavor in oral cavity/antibacterial substance that goes is chlorine dioxide.
Preferably, described natural plant essential oils are in Rosa Damascana, rose extract solution, rose, rose cell liquid One or more.
Preferably, described surfactant is Tween 80, poloxamer188, poly- D-sorbite -80, laruyl alcohol sulfuric acid One or more in sodium.
Preferably, flavouring is saccharin sodium, acesulfame potassium, stevioside, xylitol, one kind in D-sorbite or several Kind.
Preferably, described one kind or several for preventing from carious tooth and bacterial plaque material to wash in Thailand, sodium fluoride, Tinidazole Kind.
Preferably, described food coloring be famille rose, amaranth, lure it is red in one kind.
Preferably, the spray also contains the weight percent of Mint Essence and/or menthol, Mint Essence and/or menthol Than for 0.03%~0.3%.
Preferably, the spray also contains propane diols and/or glycerine, and the percentage by weight of propane diols and/or glycerine is 10% ~15%.
Preferably, the spray also contains citric acid and sodium acid carbonate, and the percentage by weight of citric acid and sodium acid carbonate is 0.005%~0.1%.
Preferably, the regulation of citric acid and sodium acid carbonate is passed through so that the pH value of oral hygiene spray is 6.8~7.2.
Preferably, oral hygiene spray is packed using aluminium aerosol bottle.
It is a kind of to go to removing abnormal flavor in oral cavity, the preparation side of antibacterial, anti-caries oral hygiene spray suitable for women and children Method:All components are added in deionized water and dissolved, are packed using aluminium aerosol bottle.
Compared with prior art, the present invention has technique effect beneficial below:
Oral hygiene spray provided by the invention, it includes removing abnormal flavor in oral cavity/antibacterial substance, natural plant essential oils, table Face activating agent, flavouring, carious tooth and bacterial plaque material, food coloring and deionized water are prevented, wherein, go removing abnormal flavor in oral cavity/suppression The content of fungus matter is only 0.00005%~0.0005%, can Efficient antibacterial, fresh breath, anti-inflammatory it is calm, realize to oral cavity Total care, the generation of mouth disease can be reduced, composition is safe;Its dosage on the premise of effective active is kept to the greatest extent may be used Can be few, improve the security of oral hygiene spray so that the sensitive group such as its suitable for women and children uses.It is experimentally confirmed that Oral hygiene spray provided by the invention can quickly eliminate oral peculiar smell, reach 99.9% to the inhibiting rate of common microbiological.
Brief description of the drawings
Fig. 1 be oral hygiene spray to garlic flavour removal effect figure, wherein, " control " is without at oral hygiene spray The paper of reason, " processing " are the paper handled by oral hygiene spray.
Fig. 2 is inhibition figure of the oral hygiene spray to different microorganisms.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and It is not to limit.
Oral hygiene spray provided by the invention, which includes, goes to removing abnormal flavor in oral cavity/antibacterial substance, natural plant essential oils, surface to live Property agent, flavouring, prevent carious tooth and bacterial plaque material, food coloring and deionized water.Concrete component and percentage by weight are as follows:
1) removing abnormal flavor in oral cavity/antibacterial substance is gone to select high-pure chlorinedioxide, percentage by weight is 0.00005%~ 0.0005%, preferably 0.00008%~0.0002%, for removing removing abnormal flavor in oral cavity, antibacterial;
2) natural plant essential oils can be Rosa Damascana, rose extract solution, rose, one kind in rose cell liquid or It is several, preferred rose cell liquid;Percentage by weight is 0.1%~10%, preferably 3%~7%, for calm anti-inflammatory;
3) surfactant can be in Tween 80, poloxamer188, poly- D-sorbite -80, sldium lauryl sulfate One or more, preferably poloxamer188;Percentage by weight is 0.001%~0.02%, preferably 0.008-0.015%;
4) flavouring can be the one or more in saccharin sodium, acesulfame potassium, stevioside, xylitol, D-sorbite, It is preferred that acesulfame potassium, stevioside, the mixture of xylitol and D-sorbite;Percentage by weight is 0.05%~0.3%, preferably 0.1%~0.2%;
5) prevent that carious tooth and bacterial plaque material from can be the one kind or several that must be washed in Thailand, sodium fluoride, Tinidazole, metronidazole Kind, preferred fluorinated sodium;Percentage by weight is 0.001%~0.005%, preferably 0.001%~0.002%, for preventing carious tooth And bacterial plaque;
6) one or more that food coloring can be for famille rose, amaranth, temptation in red, preferably amaranth;Weight hundred Divide than being 0.000001%~0.0001%, preferably 0.000009%~0.00009%.
Moreover, oral hygiene spray provided by the invention can also include following functional mass:
7) it is used for fresh breath and refresh oneself one or both of eye-catching water-soluble Mint Essence, menthol, it is preferably thin Lotus alcohol;Its percentage by weight is 0.03%~0.3%, preferably 0.15%~0.2%.
8) it is used as propane diols, the glycerine of moisturizing stabilizer, percentage by weight is 10%~15%, preferably 12.5-14.0%.
9) it is used as citric acid, the sodium acid carbonate of pH value regulator, percentage by weight is 0.005%~0.1%, preferably 0.016%~0.07%.
The preparation method of the oral spray of the present invention:Above-mentioned all components are proportionally added in appropriate amount of deionized water Constant volume after dissolving, packed using aluminium aerosol bottle.By taking 100mL as an example, above-mentioned all components are proportionally added into 90mL Dissolved in ionized water, be settled to 100mL, packed using aluminum aerosol bottle.
Oral hygiene spray provided by the invention, wherein add removing abnormal flavor in oral cavity, it is antibacterial, prevent carious tooth and bacterial plaque The material of formation, it is long-term use of, be advantageous to the health care of all groups, especially women and teenager teeth, can less mouth disease Occur;With the addition of the material to refresh the mind, available for work, study when refresh oneself or human communication in adjust oral cavity smell.With showing There is technology to compare, be adapted to consumers in general, be especially suitable for women and children, formula has more specific aim, and composition is safe, and Exist with spray form, have and absorb the advantages of rapid, easy to use, widely applicable.
Oral hygiene spray provided by the invention has advantages below:
1. Efficient antibacterial --- to the inhibiting rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;
2. fresh breath --- oral peculiar smell can be quickly eliminated, effectively prevention, alleviation halitosis, possess pure and fresh mouth whenever and wherever possible Gas;
3. anti-inflammatory is calm --- can quickly calm down that inflammation brings is not to feel, brings the oral experience releived;
4. nursing is comprehensive --- it is simple to spray, sterilize, clean the teeth, the completion of the step of permanent tooth one, being more simply, more easily Oral care method.
5. refresh the mind --- effect that is refrigerant, refreshing oneself is produced by rapid stimulation oral mucosa.
Embodiment 1
Preparation method:By taking 100mL as an example, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, it is fixed Hold to 100mL, packed using aluminum aerosol bottle.
Embodiment 2
Preparation method:By taking 100mL as an example, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, it is fixed Hold to 100mL, packed using aluminum aerosol bottle.
Embodiment 3
Preparation method:By taking 100mL as an example, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, it is fixed Hold to 100mL, packed using aluminum aerosol bottle.
In order to verify the effect of the oral hygiene spray of the present invention, part of test results is given below:
The oral hygiene spray of embodiment 4 eliminates garlic flavour
Oral hygiene spray is prepared according to embodiment 2,7g mashed garlic is applied to blank sheet of paper center in a manner of rolling, defended with oral cavity Uniformly spray 3 times on blank sheet of paper central point of raw spray, blank sheet of paper is placed at dry shady and cool ventilation, every 1min, evaluates garlic on blank sheet of paper Taste concentration, evaluate the people of number 10.Initial garlicky concentration is designated as 100, and 0 is designated as without garlicky, and other are taken with for the moment according to deep or light marking Between to put more people averages of giving a mark be the time point garlicky concentration score value, using the score value and the percentage of initial garlicky concentration to be garlicky Residual rate, residual rate are more low better.Experimental result is as shown in figure 1, after the oral hygiene spray of the present invention is sprayed with, on blank sheet of paper Garlicky rapid elimination, it is garlicky when about 90%, eight minutes can be reduced when about 50%, three minutes can be reduced at one minute to disappear substantially Lose;Without treated blank sheet of paper, at three minutes it is garlicky still have about 95% residual, garlicky residual is about at eight minutes 90%.Therefore, oral hygiene spray of the invention can be eliminated significantly garlicky, and this shows that the oral hygiene spray of the present invention exists Eliminating oral peculiar smell field has splendid effect.
The fungistatic effect of embodiment 5 is tested
The oral hygiene spray that embodiment 2 obtains is surveyed according to fungistatic effect method of testing described in GB15979-2002 It is fixed, calculate bacteriostasis rate (%).Fungistatic effect is as shown in Fig. 2 wherein, if bacteriostasis rate is X%, in fig. 2, logarithm bacteriostasis rate is lgX.Experiment shows that the inhibiting rate to Common detrimental microorganism of oral hygiene spray of the invention reaches more than 99.9%.

Claims (10)

1. a kind of remove removing abnormal flavor in oral cavity, antibacterial, anti-caries oral hygiene spray suitable for women and children, its feature exists In, according to weight meter, the spray include 0.00005%~0.0005% go removing abnormal flavor in oral cavity/antibacterial substance, 0.1%~ 10% natural plant essential oils, 0.001%~0.02% surfactant, 0.05%~0.3% flavouring, 0.001% ~0.005% prevents carious tooth and bacterial plaque material and 0.000001%~0.0001% food coloring, and surplus is deionization Water.
2. oral hygiene spray according to claim 1, it is characterised in that:Described removes removing abnormal flavor in oral cavity/antibacterial substance For chlorine dioxide.
3. oral hygiene spray according to claim 1, it is characterised in that:Described natural plant essential oils are rhodamine toner One or more in oil, rose extract solution, rose, rose cell liquid.
4. oral hygiene spray according to claim 1, it is characterised in that:Described surfactant is Tween 80, pool One or more in Luo Shamu 407, poly- D-sorbite -80, sldium lauryl sulfate.
5. oral hygiene spray according to claim 1, it is characterised in that:Flavouring is saccharin sodium, acesulfame potassium, STEVIA REBAUDIANA One or more in glucosides, xylitol, D-sorbite.
6. oral hygiene spray according to claim 1, it is characterised in that:Described prevent carious tooth and bacterial plaque material be The one or more that must be washed in Thailand, sodium fluoride, Tinidazole.
7. oral hygiene spray according to claim 1, it is characterised in that:Described food coloring is carmine, three-coloured amaranth It is red, temptation it is red in one kind.
8. oral hygiene spray according to claim 1, it is characterised in that:The spray also contains Mint Essence and/or thin The percentage by weight of lotus alcohol, Mint Essence and/or menthol is 0.03%~0.3%.
9. oral hygiene spray according to claim 1, it is characterised in that:The spray also contains propane diols and/or glycerine, The percentage by weight of propane diols and/or glycerine is 10%~15%.
10. oral hygiene spray according to claim 1, it is characterised in that:The spray also contains citric acid and bicarbonate The percentage by weight of sodium, citric acid and sodium acid carbonate is 0.005%~0.1%.
CN201710882869.7A 2017-09-26 2017-09-26 It is a kind of to remove removing abnormal flavor in oral cavity, antibacterial and anti-caries oral hygiene spray for women and children Pending CN107595697A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604767A (en) * 2019-10-23 2019-12-24 南方医科大学第三附属医院(广东省骨科研究院) Oral spray for postoperative care and preparation method thereof
CN111358741A (en) * 2020-04-30 2020-07-03 云南风联科技有限公司 Plant orange-flavored oral cavity atomized liquid and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN105125448A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral sanitary spray
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN105125448A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral sanitary spray
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604767A (en) * 2019-10-23 2019-12-24 南方医科大学第三附属医院(广东省骨科研究院) Oral spray for postoperative care and preparation method thereof
CN110604767B (en) * 2019-10-23 2021-09-07 南方医科大学第三附属医院(广东省骨科研究院) Oral spray for postoperative care and preparation method thereof
CN111358741A (en) * 2020-04-30 2020-07-03 云南风联科技有限公司 Plant orange-flavored oral cavity atomized liquid and preparation method thereof

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Effective date of registration: 20181024

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