CN107582486A - It is a kind of to be used for oral hygiene spray that is antibacterial, removing removing abnormal flavor in oral cavity, firm tooth, tooth-whitening - Google Patents

It is a kind of to be used for oral hygiene spray that is antibacterial, removing removing abnormal flavor in oral cavity, firm tooth, tooth-whitening Download PDF

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Publication number
CN107582486A
CN107582486A CN201710885023.9A CN201710885023A CN107582486A CN 107582486 A CN107582486 A CN 107582486A CN 201710885023 A CN201710885023 A CN 201710885023A CN 107582486 A CN107582486 A CN 107582486A
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China
Prior art keywords
tooth
oral hygiene
oral
hygiene spray
oral cavity
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Pending
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CN201710885023.9A
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Chinese (zh)
Inventor
蒋丽娟
谢知芳
常雪妮
薛建龙
迈克尔·里奥尼德斯·崎肯德思
纳泽·米尔
冯立雄
基特·彦姆
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Qiaokang Biotech Guangdong Co Ltd
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Xi'an Rogers Biological Science And Technology Co Ltd
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Priority to CN201710885023.9A priority Critical patent/CN107582486A/en
Publication of CN107582486A publication Critical patent/CN107582486A/en
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Abstract

The present invention provides a kind of for antibacterial, remove removing abnormal flavor in oral cavity, firm tooth, the oral hygiene spray of tooth-whitening, in percentage by weight, the oral hygiene spray include 0.000005%~0.00003% it is antibacterial/remove removing abnormal flavor in oral cavity material, 0.001%~0.005% prevents carious tooth and bacterial plaque material, 0.08%~1% firm tooth/tooth-whitening material, 5%~20% moisturizing stabilizer, 0.1%~0.5% natural plant essential oils, 0.001%~0.002% surfactant, 0.5%~3% flavouring, 0.0000009%~0.000015% food coloring, 0.001%~0.5% pH value regulator and the deionized water of surplus.The oral hygiene spray Efficient antibacterial and can remove removing abnormal flavor in oral cavity, can prevent the formation of carious tooth and bacterial plaque, can tooth-whitening and firm tooth, effectively reduce mouth disease;Natural plant essential oils can be used for work, study when refresh oneself or human communication in adjust oral cavity smell.

Description

It is a kind of be used for it is antibacterial, go to removing abnormal flavor in oral cavity, firm tooth, the oral cavity of tooth-whitening to defend Raw spray
Technical field
The invention belongs to daily chemicals field, more particularly to it is a kind of be used for it is antibacterial, go removing abnormal flavor in oral cavity, firm tooth, The oral hygiene spray of tooth-whitening.
Background technology
With the development of the society, people also increasingly improve for the health care demand in oral cavity.It is but at the same time, pre- due to lacking Anti- and treatment, China's mouth disease illness rate is high, scope is wide, and the permanent teeth caries prevalence rate of adult is 49.88%, children's Primary Caries rate 80%th, periodontosis illness rate about 90%, 65-74 year old man averagely lose tooth number and are up to 11.If by all mouth disease bags Including including (such as canker sore, toothache, periodontitis, bleeding gums, calculus dentalis, halitosis), it may be said that almost everybody has oral cavity Disease, the incidence of disease are almost 100%.Meanwhile there is smoker more than 300,000,000 in China, the xanthodont cigarette tooth rate of black tooth is more than 90%, if counting coffee in Coffee stain, tea stain, the crowd of betel nut stain and bacterial plaque, Chinese at least 800,000,000 people need tooth whitening.Various mouth diseases are prevented and treated, Except drug therapy, regular oral health routine holds the balance, outer except periodically brushing teeth, and researches and develops one kind and is convenient for carrying, convenient use, kills Bacterium anti-inflammatory, the gargle in nursing oral cavity become extremely significant.
Suppress oral bacteria, remove the important content that the firm tooth of removing abnormal flavor in oral cavity, whitening is oral care.Oral cavity anaerobism is thin Bacterium is the arch-criminal of various oral problems.These anaerobic bacterias decompose the protein in swill and saliva, produce a variety of There is the gas of peculiar smell, make one to produce halitosis;Catabolite is attached on tooth for a long time can corrode tooth, produce bacterial plaque, easily Cause a variety of periodontal diseases.Tooth pigmentation phenomenon can all be produced by smoking, having tea etc. simultaneously, have a strong impact on beautiful teeth, shadow Ring the quality of life of people.Chlorine dioxide antiseptic power is strong, has a broad antifungal spectrum, has killing to make to bacterium, virus, fungi and gemma etc. With, and act on it is rapid, bactericidal effect influenceed by environmental condition (temperature, pH value, organic matter) it is small, it is nontoxic, non-stimulated, to environment without Pollution, is used in many oral care products in American-European countries, for tooth whitening and health care, pre- anti-caries and periodontal disease Disease, in particular for the preventing and treating of halitosis.Experimental results demonstrate chlorine dioxide can kill oral cavity anaerobium, mouth is fundamentally treated Smelly, oral health benefits are significantly better than other its products.Sea salt has sterilization, anti-inflammatory effect, can be with firm, tooth-whitening, will It is added in gargle, not only can be with antibacterial, while can enrich the flavor of rinse product.
The content of the invention
It is an object of the invention to provide a kind of oral hygiene spray, suitable for all groups, especially smoking population or There is the crowd of peculiar smell in oral cavity, can effectively go removing abnormal flavor in oral cavity, antibacterial, tooth-whitening and energy anti-caries.
The present invention is to be achieved through the following technical solutions:
It is a kind of to be used for oral hygiene spray that is antibacterial, removing removing abnormal flavor in oral cavity, firm tooth, tooth-whitening, according to weight hundred Point than meter, the oral hygiene spray include 0.000005%~0.00003% it is antibacterial/remove removing abnormal flavor in oral cavity material, 0.001% ~0.005% prevents carious tooth and bacterial plaque material, 0.08%~1% firm tooth/tooth-whitening material, 5%~20% Moisturizing stabilizer, 0.1%~0.5% natural plant essential oils, 0.001%~0.002% surfactant, 0.5%~ 3% flavouring, 0.0000009%~0.000015% food coloring, 0.001%~0.5% pH value regulator and remaining The deionized water of amount.
Preferably, it is described it is antibacterial/to remove removing abnormal flavor in oral cavity material be chlorine dioxide.
Preferably, described one kind or several for preventing from carious tooth and bacterial plaque material to wash in Thailand, sodium fluoride, metronidazole Kind.
Preferably, described firm tooth/tooth-whitening material is sea salt and bamboo salt.
Preferably, described moisturizing stabilizer is propane diols and glycerine.
Preferably, described surfactant be tween, poloxamer188, sell pool, one kind in sldium lauryl sulfate or It is several.
Preferably, described flavouring is one kind in saccharin sodium, acesulfame potassium, stevioside, xylitol, D-sorbite It is or several.
Preferably, described natural plant essential oils are water-soluble Mint Essence and menthol.
Preferably, described food coloring is one kind in light blue, indigo, gardenia blue, algae basket.
Preferably, described pH value regulator is citric acid and sodium acid carbonate.
It is further preferred that the percentage by weight of pH value regulator is 0.026%~0.1%.
It is further preferred that pH value regulator adjusts the pH of oral hygiene spray to 6.2~7.6.Further, pH Value conditioning agent adjusts the pH of oral hygiene spray to 6.8~7.2.
Preferably, the oral hygiene spray solution of all components composition is packaged in aluminium aerosol bottle.
Compared with prior art, the present invention has technique effect beneficial below:
Oral hygiene spray provided by the invention, including antibacterial/remove removing abnormal flavor in oral cavity material, prevent carious tooth and bacterial plaque thing Matter, firm tooth/tooth-whitening material, moisturizing stabilizer, surfactant, flavouring, natural plant essential oils, food coloring, PH value regulator and deionized water.It is antibacterial/to go removing abnormal flavor in oral cavity material Efficient antibacterial and removing abnormal flavor in oral cavity can be removed, prevent carious tooth The formation of carious tooth and bacterial plaque can be prevented with bacterial plaque material, firm tooth/tooth-whitening material being capable of tooth-whitening and heavily fortified point Gu tooth, natural plant essential oils can be used for work, study when refresh oneself or human communication in adjust oral cavity smell.The oral hygiene is sprayed Agent can effectively reduce mouth disease.It is demonstrated experimentally that the oral hygiene spray can remove rapidly it is garlicky on blank sheet of paper, its 99% is up to the inhibiting rate of common causative microorganism (staphylococcus aureus, Escherichia coli, candida albicanses), can be effective Reach removing abnormal flavor in oral cavity, antibacterial purpose.
Brief description of the drawings
Fig. 1 be oral hygiene spray to garlic flavour removal effect figure, wherein, " processing " be handled using oral hygiene spray Blank sheet of paper, " control " is the blank sheet of paper that is not handled by oral hygiene spray.
Fig. 2 is inhibition of the oral hygiene spray to different microorganisms.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and It is not to limit.
It is an object of the invention to provide a kind of oral hygiene spray, suitable for all groups, especially smoking population or There is the crowd of peculiar smell in oral cavity, can effectively go removing abnormal flavor in oral cavity, antibacterial, tooth-whitening and energy anti-caries.
The mouth sprays include it is antibacterial/remove removing abnormal flavor in oral cavity material, prevent carious tooth and bacterial plaque material, firm tooth/U.S. White tooth substances, moisturizing stabilizer, surfactant, flavouring, natural plant essential oils, food coloring, pH value regulator and go Ionized water.Its concrete component and percentage by weight are as follows:
1) it is antibacterial/to go removing abnormal flavor in oral cavity material to select high-pure chlorinedioxide, percentage by weight is 0.000005%~ 0.00003%, preferably 0.00001%~0.00003%;
2) carious tooth is prevented and one or more that the selection of bacterial plaque material must be washed in Thailand, sodium fluoride, metronidazole, preferred fluorinated Sodium;Percentage by weight is 0.001%~0.005%, preferably 0.0015~0.0021%;
3) firm tooth/tooth-whitening material selects sea salt and bamboo salt, and percentage by weight is 0.08%~1%, preferably 0.4%-0.6%;
4) moisturizing stabilizer selects propane diols and glycerine, and percentage by weight is 5%~20%, preferably 12.0%-13.0%;
5) surfactant from tween, poloxamer188, sell pool, the one or more in sldium lauryl sulfate, preferably Poloxamer188, percentage by weight are 0.001%~0.002%, preferably 0.0015%;
6) one or more that flavouring is selected in acesulfame potassium, Niu Siba sweet teas, stevioside, xylitol, D-sorbite, It is preferred that stevioside and xylitol;Percentage by weight is 0.5%~3%, preferably 1.4%~1.8%;
7) natural plant essential oils select water-soluble Mint Essence and menthol, and percentage by weight is 0.1%~0.5%, excellent Select 0.14%~0.24%;
8) food coloring is one kind in light blue, indigo, gardenia blue, algae basket, preferably light blue;Percentage by weight is 0.0000009%~0.000015%, preferably 0.000001%.
9) pH value regulator is citric acid and sodium acid carbonate, and percentage by weight is 0.001%~0.5%, preferably 0.026% ~0.1%;
10) surplus is deionized water.
The preparation method of the oral spray of the present invention:Above-mentioned all components are proportionally added into deionized water and dissolved, Packed using aerosol bottle.
Oral hygiene spray provided by the invention, wherein add removing abnormal flavor in oral cavity, it is antibacterial, prevent carious tooth and bacterial plaque The material of formation and firm, tooth-whitening composition, it is long-term use of, be advantageous to the health care of oral cavity and tooth, tooth whitening can be kept, Less mouth disease occurs;With the addition of natural plant essential oils (there is functions of refreshing brain and restoring consciousness), available for work, study when refresh oneself or Oral cavity smell is adjusted in human communication.Compared with prior art, it is adapted to consumers in general, being especially suitable for smoking population or oral cavity has The crowd of peculiar smell, it can effectively go removing abnormal flavor in oral cavity, antibacterial and energy anti-caries.Formula has more specific aim, and composition is safe, and Exist with spray form, have and absorb the advantages of rapid, easy to use, widely applicable.
Oral hygiene spray provided by the invention has advantages below:
1. Efficient antibacterial --- to the inhibiting rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;
2. fresh breath --- oral peculiar smell can be quickly eliminated, effectively prevention, alleviation halitosis, possess pure and fresh mouth whenever and wherever possible Gas;
3. deeply cleaning --- the deep spot being hidden in teeth space can be quickly removed, and gos deep into pharyngeal cleaning oral cavity comprehensively;
4. avoid wearing --- avoid brushing teeth the enamel abrasion brought, makes tooth more bright and clean charming;
5. avoid bleeding --- caused bleeding gums of brushing teeth are avoided, make oral cavity anti-virus ability stronger;
6. nursing is comprehensive --- it is simple to spray, sterilize, clean the teeth, the completion of the step of permanent tooth one, being more simply, more easily Oral care method.
Embodiment 1
Preparation method:In terms of 100mL, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, constant volume To 100mL, packed using aluminum aerosol bottle.
Embodiment 2
Preparation method:In terms of 100mL, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, constant volume To 100mL, packed using aluminum aerosol bottle.
Embodiment 3
Preparation method:In terms of 100mL, above-mentioned all components are proportionally added in 90mL deionized waters and dissolved, constant volume To 100mL, packed using aluminum aerosol bottle.
The effect of anti-inflammatory gargle in oral cavity provided by the invention is illustrated below.
The mouth sprays of embodiment 4 eliminate garlic flavour
Mouth sprays are prepared according to embodiment 1,7g mashed garlic is applied to blank sheet of paper center in a manner of rolling, existed with mouth sprays Uniformly spray 3 times, blank sheet of paper is placed at dry shady and cool ventilation on blank sheet of paper central point, every 1min, is evaluated garlicky concentration on blank sheet of paper, is commented The people of valency number 10.Initial garlicky concentration is designated as 100, and 0 is designated as without garlicky, and other concentration are taken with for the moment according to garlicky deep or light marking Between to put more people averages of giving a mark be the time point garlicky concentration score value, using the score value and the percentage of initial garlicky concentration to be garlicky Residual rate, residual rate are more low better.As a result show in Fig. 1.As a result show, after the oral hygiene spray of the present invention is sprayed with, Garlicky rapid elimination on blank sheet of paper, garlic when about 80%, eight minutes can be reduced when about 45%, three minutes can be reduced at one minute Taste disappears substantially;Without treated blank sheet of paper, at three minutes it is garlicky still have about 95% residual, it is garlicky residual at eight minutes Stay about 90%.Therefore, oral hygiene spray of the invention can be eliminated significantly garlicky, and this shows the oral hygiene spray of the present invention Agent has splendid effect in elimination oral peculiar smell field.
The fungistatic effect of embodiment 5 is tested
The mouth sprays that embodiment 4 obtains are measured according to fungistatic effect method of testing described in GB15979-2002, Calculate bacteriostasis rate (%).Experimental results show in fig. 2, wherein, if bacteriostasis rate is X%, logarithm bacteriostasis rate is lgX.Experiment Show, oral hygiene spray of the invention is to Common detrimental microorganism (staphylococcus aureus, Escherichia coli, Candida albicans ball Bacterium) inhibiting rate reach more than 99%, there is good fungistatic effect.

Claims (10)

1. a kind of be used for oral hygiene spray that is antibacterial, removing removing abnormal flavor in oral cavity, firm tooth, tooth-whitening, it is characterised in that presses According to percentage by weight meter, the oral hygiene spray include 0.000005%~0.00003% it is antibacterial/remove removing abnormal flavor in oral cavity thing Matter, 0.001%~0.005% prevent carious tooth and bacterial plaque material, 0.08%~1% firm tooth/tooth-whitening material, 5%~20% moisturizing stabilizer, 0.1%~0.5% natural plant essential oils, 0.001%~0.002% surface-active Agent, 0.5%~3% flavouring, 0.0000009%~0.000015% food coloring, 0.001%~0.5% pH value The deionized water of conditioning agent and surplus.
2. oral hygiene spray according to claim 1, it is characterised in that it is described it is antibacterial/remove removing abnormal flavor in oral cavity material For chlorine dioxide.
3. oral hygiene spray according to claim 1, it is characterised in that described prevent carious tooth and bacterial plaque material be The one or more that must be washed in Thailand, sodium fluoride, metronidazole.
4. oral hygiene spray according to claim 1, it is characterised in that described firm tooth/tooth-whitening material For sea salt and bamboo salt.
5. oral hygiene spray according to claim 1, it is characterised in that described moisturizing stabilizer is propane diols and sweet Oil.
6. oral hygiene spray according to claim 1, it is characterised in that described surfactant is tween, pool Lip river Husky nurse 407, sell pool, the one or more in sldium lauryl sulfate.
7. oral hygiene spray according to claim 1, it is characterised in that described flavouring be saccharin sodium, acesulfame potassium, One or more in stevioside, xylitol, D-sorbite.
8. oral hygiene spray according to claim 1, it is characterised in that described natural plant essential oils are thin, water soluble Lotus essence and menthol.
9. oral hygiene spray according to claim 1, it is characterised in that described food coloring is light blue, indigo, Cape jasmine One kind in sub blue, algae basket.
10. oral hygiene spray according to claim 1, it is characterised in that described pH value regulator be citric acid and Sodium acid carbonate.
CN201710885023.9A 2017-09-26 2017-09-26 It is a kind of to be used for oral hygiene spray that is antibacterial, removing removing abnormal flavor in oral cavity, firm tooth, tooth-whitening Pending CN107582486A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110013451A (en) * 2019-05-16 2019-07-16 华纳时代健康科技(武汉)股份有限公司 A kind of oral bacteriostasis liquid and production technology
CN110327250A (en) * 2018-06-08 2019-10-15 中国医学科学院药用植物研究所 A kind of pure natural sterilizing oral spray and preparation method thereof
CN110538084A (en) * 2018-05-28 2019-12-06 张玉波 Compound for synergistically resisting dental plaque and inhibiting dental ulcer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN1271573A (en) * 1999-04-28 2000-11-01 孙廷柱 Multifunctional gargle
CN105125448A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral sanitary spray
CN105125690A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation spray
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1222345A (en) * 1997-12-01 1999-07-14 段建涛 Gargle containing chlorine dioxide
CN1271573A (en) * 1999-04-28 2000-11-01 孙廷柱 Multifunctional gargle
CN105125448A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral sanitary spray
CN105125690A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation spray
CN105147612A (en) * 2015-09-23 2015-12-16 北京水木中天植物科学研究院 Oral cavity refreshing spray agent

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110538084A (en) * 2018-05-28 2019-12-06 张玉波 Compound for synergistically resisting dental plaque and inhibiting dental ulcer
CN110327250A (en) * 2018-06-08 2019-10-15 中国医学科学院药用植物研究所 A kind of pure natural sterilizing oral spray and preparation method thereof
CN110327250B (en) * 2018-06-08 2023-04-14 中国医学科学院药用植物研究所 Pure natural oral sterilization spray and preparation method thereof
CN110013451A (en) * 2019-05-16 2019-07-16 华纳时代健康科技(武汉)股份有限公司 A kind of oral bacteriostasis liquid and production technology

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Application publication date: 20180116