CN107412111A - A kind of oral cavity anti-inflammatory gargle - Google Patents

A kind of oral cavity anti-inflammatory gargle Download PDF

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Publication number
CN107412111A
CN107412111A CN201710833358.6A CN201710833358A CN107412111A CN 107412111 A CN107412111 A CN 107412111A CN 201710833358 A CN201710833358 A CN 201710833358A CN 107412111 A CN107412111 A CN 107412111A
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CN
China
Prior art keywords
oral cavity
gargle
inflammatory
oral
following components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710833358.6A
Other languages
Chinese (zh)
Inventor
薛建龙
常雪妮
蒋丽娟
谢知芳
基特·彦姆
迈克尔·里奥尼德斯·崎肯德思
纳泽·米尔
冯立雄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qiaokang Biotech Guangdong Co Ltd
Original Assignee
Xi'an Rogers Biological Science And Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xi'an Rogers Biological Science And Technology Co Ltd filed Critical Xi'an Rogers Biological Science And Technology Co Ltd
Priority to CN201710833358.6A priority Critical patent/CN107412111A/en
Publication of CN107412111A publication Critical patent/CN107412111A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

The invention discloses a kind of oral cavity anti-inflammatory gargle, its formula is made up of natural plant essential oils, surfactant, Mint Essence, menthol, food coloring, soda, sea salt, bamboo salt, citric acid, xylitol, ethanol and deionized water, anti-inflammatory gargle in oral cavity provided by the invention can prevention of gingivitis, reduce dental plaque, eliminate oral peculiar smell, and growing for oral cavity bacterium can be prevented, so as to effectively prevent various mouth diseases, used suitable for various people.

Description

A kind of oral cavity anti-inflammatory gargle
Technical field
The invention belongs to daily chemicals technical field, and in particular to a kind of oral cavity anti-inflammatory gargle.
Background technology
With the continuous progress of society, people increasingly focus on self-image in contacts.Except dressing and talk Outside manner, the smell for having been noted that in the mouth is also a part for self-image.It is universal that oral peculiar smell has become people in recent years The topic spoken of.However, cause the main reason of halitosis to be a large amount of bacteriums in human mouth, these bacteriums decompose swill and Protein in saliva, produce a variety of gases for having peculiar smell.The oxygen-containing sufficiently saliva of flowing can suppress bacterial reproduction and dissolve These gases are diluted without producing obvious taste.There is mouth because night salivary secretion is reduced when from morning in many normal persons It is smelly, but with feeding, gargle, excessive saliva and disappear.In addition, with advancing age, the flowing of saliva is gradually slack-off, because This, the elderly has the worry of more halitosis than young man.Ethanol, starvation, excessive talk, nasal obstruction, during taking exercises Any factor of dry is caused to produce halitosis with mouth breathing etc..In addition to halitosis, because teeth brushing way is incorrect, life The various oral problems caused by reason, such as gingivitis, bacterial plaque, children's decayed tooth carious tooth, aged dental root caries such as work and rest irregular, Also the quality of life of people is being affected.
The gargle class product of commercial type at present, most effect is single, and effect and unobvious.Therefore develop The gargle that can prevent a variety of oral problems with extensive adaptability is significant.
The content of the invention
It is an object of the invention to provide a kind of oral cavity anti-inflammatory gargle, the gargle enough prevents the taste of oral cavity bacterium It is long, so as to effectively prevent various mouth diseases, used suitable for various people.
The present invention is to be achieved through the following technical solutions:
A kind of oral cavity anti-inflammatory gargle disclosed by the invention, it is by percentage to the quality, composed of the following components:
Preferably, by percentage to the quality, it is composed of the following components:
Preferably, by percentage to the quality, it is composed of the following components:
Preferably, by percentage to the quality, it is composed of the following components:
Preferably, described natural plant essential oils are lemon.Preferably, described surfactant is poloxamer 407。
Preferably, described food coloring is lemon yellow.
Preferably, the water is deionized water.
Compared with prior art, the present invention has technique effect beneficial below:
Anti-inflammatory gargle in oral cavity provided by the invention, adds natural plant essential oils, Mint Essence, menthol and sea salt, Can prevention of gingivitis, reduce dental plaque, eliminate oral peculiar smell, and growing for oral cavity bacterium can be prevented, so as to effective Prevent various mouth diseases, used suitable for various people.Wherein adding surfactant has the function that to strengthen cleaning, adds thin Lotus brain has the effect of refreshing oneself, restoring consciouness, may feel that the residue in oral cavity is cleaned out after use, tooth, teeth space become Totally, have a kind of refrigerant sensation, then with tongue rub facing slightly on the strength a little swallowed, can feel very clean in oral cavity Only, the mucus in oral cavity significantly reduces, and teeth space distributes a kind of refreshing cold air from inside to outside, makes us being in a cheerful frame of mind.It is this Sensation can be kept for a very long time in oral cavity, make one spiritual straightforward, that is bored feels to be improved.Added in the present invention Xylitol is the best sweetener of anti-caries, obtains certification in varied situations within the time of 25 years.Xylitol can subtract This characteristic of few carious tooth, in high-risk rate crowd (carious tooth incidence height, Undernutrition, oral hygiene level are low) and low level of significance It is applicable in crowd's (being taken care of one's teeth using current all cleaning of teeth measures, dental cavity generation rate is low).Added in the present invention Sea salt there is the effect of bactericidal, it is rich in the necessary mineral matter of human body, and oral cavity can be made to produce more salivas, with lubrication Food, favorably chew, swallow and digest, can also strengthen, the unsound tooth of remineralization, firm gum, functions of whitening teeth.Cause This, the oral cavity anti-inflammatory gargle that above-mentioned formula is formed, has advantages below:
1. Efficient antibacterial --- to the inhibiting rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances;
2. fresh breath --- oral peculiar smell can be quickly eliminated, effectively prevention, alleviation halitosis, fresh breath;
3. cleaning is deeply --- the deep spot being hidden in teeth space can be quickly removed, gos deep into pharyngeal cleaning oral cavity comprehensively;
4. avoid wearing --- avoid brushing teeth the enamel abrasion brought, makes tooth brighter and cleaner;
5. avoid bleeding --- caused bleeding gums of brushing teeth are avoided, make oral cavity anti-virus ability stronger;
6. nursing is comprehensive --- sterilization is reached by a step of gargling, cleaned the teeth, permanent tooth effect.
Further, the natural plant essential oils added in anti-inflammatory gargle in oral cavity of the invention select lemon, have Act on below:Improve Oily, skin lightening, whitening purifying skin, improve rupture capilary, remove old dead cell, except corn, flat Wart;Stimulate circulation, mitigate varication;Hypotensive, improve anaemia;Mitigate headache, gout, arthritis;Anti-infective, sense Emit, inflammation;Aid digestion, the clarification state of mind;Lemon has growth inhibition to common cariogenic bacteria such as streptococcus mutans, streptococcus sobrinus Effect, and have scavenging action to free radical.
Brief description of the drawings
Fig. 1 is anti-inflammatory gargle in oral cavity disclosed by the invention to garlic flavour removal effect;
Fig. 2 is fungistatic effect figure of the anti-inflammatory gargle in oral cavity disclosed by the invention to different microorganisms.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and It is not to limit, embodiments of the invention not limited to this, for especially not dated technological parameter or condition, can refer to routine techniques Carry out.
Anti-inflammatory gargle in oral cavity provided by the invention, it includes natural plant essential oils, surfactant, minty note in being formulated Essence, menthol, food coloring, soda, sea salt, bamboo salt, citric acid, xylitol, ethanol and deionized water.Can prevention of gingivitis, Reduce dental plaque, eliminate oral peculiar smell.
Preferably, surfactant uses poloxamer188, and natural plant essential oils use the fresh lemon within the shelf-life Lemon essential oil, food coloring select lemon yellow.
Specifically, the weight/mass percentage composition of each component is as follows in anti-inflammatory gargle in oral cavity provided by the invention:
Natural plant essential oils (lemon) 0.0025%~0.003%, surfactant (poloxamer188) 0.001%th, Mint Essence 0.05%~0.1%, menthol 0.01%~0.015%, food coloring (lemon yellow) 0.000012%th, soda 0.01%, sea salt 0.1%~0.2%, bamboo salt 0.1%~0.2%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
With reference to the present invention preferably embodiment, the present invention is described in further details.
Embodiment 1
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components:Natural plant essential oils (lemon extract Oil) 0.0025%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.08%, menthol 0.012%, edible Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.1%, bamboo salt 0.1%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method:Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters, Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 2
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components:Natural plant essential oils (lemon extract Oil) 0.003%, surfactant (poloxamer188) 0.001%, Mint Essence 0.1%, menthol 0.015%, edible color Plain (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.15%, bamboo salt 0.15%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method:Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters, Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 3
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components:Natural plant essential oils (lemon extract Oil) 0.0026%, surfactant (poloxamer188) 0.001%, Mint Essence 0.09%, menthol 0.01%, edible color Plain (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.2%, bamboo salt 0.2%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method:Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters, Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 4
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components:Natural plant essential oils (lemon extract Oil) 0.0027%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.06%, menthol 0.013%, edible Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.12%, bamboo salt 0.18%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method:Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters, Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 5
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components:Natural plant essential oils (lemon extract Oil) 0.0028%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.05%, menthol 0.011%, edible Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.18%, bamboo salt 0.12%, citric acid 0.002%, xylitol 0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method:Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters, Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
The effect of anti-inflammatory gargle in oral cavity provided by the invention is illustrated below.
1st, anti-inflammatory gargle in oral cavity eliminates garlic taste effect disquisition
7g mashed garlic is applied to blank sheet of paper center in a manner of rolling, the oral cavity anti-inflammatory gargle made from the embodiment of the present invention 1 Uniformly spray 3 times, blank sheet of paper is placed at dry shady and cool ventilation on blank sheet of paper central point, every 1min, evaluates garlicky concentration on blank sheet of paper, The people of evaluation number 10.Initial garlicky concentration is designated as 100, is designated as 0 without garlicky, other take same time point more according to deep or light marking People's marking average is the time point garlicky concentration score value, using the score value and the percentage of initial garlicky concentration as garlicky residual Rate, residual rate are more low better.Residual rate result is as shown in figure 1, it can be seen from figure 1 that gargle described in the present embodiment can be in the short time Garlic flavour is reduced to 50% or so, 7min or so and is completely removed garlic flavour by interior (about 1min), and is not added with any gargle Blank sheet of paper (compare) on garlic taste still largely remained in 8min.This experiment demonstrates the gargle and removes having for garlic flavour Effect property.
2nd, fungistatic effect is tested
By anti-inflammatory gargle in oral cavity made from the embodiment of the present invention 4 according to fungistatic effect test side described in GB15979-2002 Method is measured, and calculates bacteriostasis rate, as a result as shown in Figure 2.From figure 2 it can be seen that shield tooth in oral cavity produced by the present invention is gargled Liquid is effective to staphylococcus aureus, Escherichia coli and candida albicanses, to staphylococcus aureus and Escherichia coli Bacteriostasis rate is of a relatively high.
3rd, specifically used example
In order to verify the effect of the oral cavity anti-inflammatory gargle of the present invention, many experiments are carried out, it is specific that some are given below Case:
Case 1, thank so-and-so:Man, 37 years old, on ordinary days because teeth brushing way is incorrect, bacterial plaque was serious, used within continuous 1 month The oral cavity anti-inflammatory gargle of the present invention, daily 6-8 times, bacterial plaque substantially mitigates at present.
Case 2, Lv:Man, 41 years old, on ordinary days because teeth brushing way is incorrect, love was had tea, and had obvious tartar in teeth space, even Continuous 1 first quarter moon is using the oral cavity shield tooth gargle of the present invention, and daily 3-4 times, tartar significantly reduces at present.
Case 3, Wang:Female, 60 years old, bleeding gums were serious when brushing teeth on ordinary days, and continuous two weeks uses oral cavity of the invention Anti-inflammatory gargle, daily 3-4 times, bleeding gums problem is effectively alleviated at present.
Case 4, marquis so-and-so:Man, 44 years old, smoke and drink on ordinary days, be known as halitosis, the continuous 2 months oral cavities using the present invention Anti-inflammatory gargle, daily 3-4 times, halitosis disappears substantially at present.
Case 5, Lin:Female, 28 years old, because operating pressure is big and often stays up late and causes swelling and aching of gum, use in continuous 5 days The oral cavity anti-inflammatory gargle of the present invention, daily 3-4 times, swelling and aching of gum problem is effectively alleviated at present.

Claims (8)

1. a kind of oral cavity anti-inflammatory gargle, it is characterised in that by percentage to the quality, composed of the following components:
2. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components Composition:
3. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components Composition:
4. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components Composition:
5. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that described natural plant Thing essential oil is lemon.
6. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that live on described surface Property agent is poloxamer188.
7. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that described edible color Element is lemon yellow.
8. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that the water for go from Sub- water.
CN201710833358.6A 2017-09-15 2017-09-15 A kind of oral cavity anti-inflammatory gargle Pending CN107412111A (en)

Priority Applications (1)

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Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431901A (en) * 2018-12-13 2019-03-08 中原工学院 A kind of effectively antibacterial salting liquid of gargling

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105125690A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation spray
CN105125425A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation collutory

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105125690A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation spray
CN105125425A (en) * 2015-09-23 2015-12-09 北京水木中天植物科学研究院 Oral anti-inflammation collutory

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431901A (en) * 2018-12-13 2019-03-08 中原工学院 A kind of effectively antibacterial salting liquid of gargling

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Effective date of registration: 20181024

Address after: 514000 Meizhou, Meijiang, Guangdong Meijiang District bin Fang South Hongxing Garden 6, 7 duplex shop

Applicant after: Lo Riggs (Guangdong) Biotechnology Co., Ltd.

Address before: 710075, 8 floor, 10802-8690 Reggae building, 15 hi tech two road, hi tech Zone, Xi'an, Shaanxi.

Applicant before: Xi'an Rogers biological science and Technology Co Ltd

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Address after: 511400 Room 1301, 132, Nansha Street, Nansha District, Guangzhou, Guangdong Province, South 162 Qian Avenue, Nansha Street (office only)

Applicant after: Qiaokang Biotechnology (Guangdong) Co., Ltd.

Address before: 514000 Meizhou, Meijiang, Guangdong Meijiang District bin Fang South Hongxing Garden 6, 7 duplex shop

Applicant before: Lo Riggs (Guangdong) Biotechnology Co., Ltd.

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Application publication date: 20171201