KR20100041922A - Mouthwash which include the chrysanthemum, germander and japonica extract - Google Patents

Mouthwash which include the chrysanthemum, germander and japonica extract Download PDF

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KR20100041922A
KR20100041922A KR1020080100961A KR20080100961A KR20100041922A KR 20100041922 A KR20100041922 A KR 20100041922A KR 1020080100961 A KR1020080100961 A KR 1020080100961A KR 20080100961 A KR20080100961 A KR 20080100961A KR 20100041922 A KR20100041922 A KR 20100041922A
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oral
chrysanthemum
betony
mouthwash
bad breath
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KR1020080100961A
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Korean (ko)
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최정영
이주영
김진수
최부근
장희경
박향숙
심수현
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최정영
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A61Q11/02Preparations for deodorising, bleaching or disinfecting dentures

Abstract

PURPOSE: An oral gargle liquid containing natural medicinal herbs is provided to ensure oral hygiene with safety to human body and to prevent superinfection or xerostomia. CONSTITUTION: An oral gargle liquid contains chrysanthemum, betony, and nepta herb extract. Main ingredients of betony are trimethylcyclohexane, carboxylic acid, and acacetin. The betony has effect of suppressing fungi, E.coli, pneumococcus, and hemolytic Streptococcus. The nepta herb contains menthol and limonene. The oral gargle liquid additionally contains fluorine, surfactant, perfume and sweetener.

Description

국화, 곽향 및 형개 추출물을 함유한 구강양치액{Mouthwash which include the chrysanthemum, germander and japonica extract}Mouthwash which contains the chrysanthemum, narcissus and mold extract {Mouthwash which include the chrysanthemum, germander and japonica extract}

본 발명은 한약재를 이용한 구강양치액에 관한 것으로, 국화, 곽향 및 형개 추출물을 이용한 것이다.    The present invention relates to a mouthwash using a herbal medicine, using the chrysanthemum, kwakhyang and mold opening extract.

구강에서 발생하는 구강증상은 구내염, 치아우식 및 구취로 구분할 수 있다. 구내염인 치은염이나 치주질환은 세균감염에 의해 유발될 수 있다. 급성포진성 치은 구내염, 급성궤사 궤양성치은염 및 치주질환 등이 여기에 속한다. 치은염이나 치주염이 있으면 염증성 상태에서 구취가 증가하게 된다. 물론 이때 구취를 유발하는 휘발성 황화합물과 메틸머켑탄이라는 물질의 농도가 높아지게 된다. 즉 구내염의 치료는 구취과 관련이 있다.  Oral symptoms occurring in the oral cavity can be divided into stomatitis, dental caries and bad breath. Stomatitis or periodontal disease can be caused by bacterial infection. Acute herpes gingivitis, acute ulcer ulcerative gingivitis, and periodontal disease. If you have gingivitis or periodontitis, bad breath can increase in inflammatory conditions. Of course, the concentrations of volatile sulfur compounds and methylmerethane are causing the bad breath. In other words, the treatment of stomatitis is associated with bad breath.

구취의 원인은 전신질환 또는 구강내 염증이 원인이다. 구취가 발생하는 구강내 요인으로는 (1) 불량한 구강위생, (2) 치주병(잇몸질환), (3) 치아우식증(충치), (4) 설태, (5) 타액분비량 감소, (6) 더러운 틀니 등을 생각할 수 있다. 그 밖에 술, 담배, 마늘 등 섭취하는 음식의 종류에 따라서도 구취를 유발할 수 있다.   The cause of bad breath is a systemic disease or inflammation in the mouth. Oral causes of bad breath include (1) poor oral hygiene, (2) periodontal disease (gum disease), (3) dental caries (caries), (4) pregnancies, (5) salivation, and (6) You can think of dirty dentures. In addition, alcohol, tobacco, garlic, etc., depending on the type of food you eat can cause bad breath.

구강내에는 단백질과 아미노산 등을 분해하는 많은 세균이 살고 있다. 세균은 음식잔사를 분해하여 구취를 유발한다. 따라서 구취는 일차적으로 세균에 의한 세균성 부패 및 휘발성 황화합물의 생성에 의해 나타나는 것으로 알려져 있다. 구취가 있다면 치주질환이 존재하거나 또는 구강환경관리가 부족한 것이 아닌지 생각해보아야 하겠다.    Many bacteria live in the oral cavity to break down proteins and amino acids. Bacteria break down food residues and cause bad breath. Therefore, bad breath is known to be primarily caused by bacterial decay and the production of volatile sulfur compounds by bacteria. If you have bad breath, you should consider whether you have periodontal disease or lack of oral care.

구강양치액은 충치예방, 항미생물 작용, 불소 전달 및 플라그 제거 등의 용도로 사용한다. 구강건강의 목적으로 알콜, 계면활성제, 클로르헥시딘, 불소 및 향료 등을 첨가하여 제조한다. 알콜은 각종 성분의 용해 목적으로 사용되고, 계면활성제는 치면세균막의 형성을 억제하는데 작용을 한다. 클로르헥시딘은 소독제로서 구강내 세균을 사멸하며 구강내 염증을 완화하는 목적으로 사용한다. 불소는 치아의 우식예방 목적으로 사용하며, 여기에 향을 주기 위하여 menthol, thymol 등의 향료를 첨가한다.   Mouthwash is used for prevention of tooth decay, antimicrobial action, fluorine transfer and plaque removal. For the purpose of oral health, it is prepared by adding alcohol, surfactant, chlorhexidine, fluorine and flavorings. Alcohols are used for the purpose of dissolving various components, and surfactants act to suppress the formation of dental plaque. Chlorhexidine is used as a disinfectant to kill oral bacteria and to relieve oral inflammation. Fluoride is used for the purpose of preventing caries, and flavors such as menthol and thymol are added to give flavor.

고농도의 에탄올이 함유된 구강양치액을 사용하면 치아 수복재인 레진계열의 표면을 약하게 만들며, 구강건조증을 유발하는 것으로 보고되고 있다. 알코올의 사용에 의해 타액분비율이 심하게 감소할 경우 구강건조증이 된다. 일반적으로는 타액선을 침범하는 질환이 있는 경우나 쇼그렌증후군 같은 질환이 있는 경우에 생기게 된다. 이 경우 타액내 미생물의 밀도가 높아지고 연하(삼키는 것)가 줄어들어 구강에 머무는 시간이 길어져 구취의 원인물질 생성이 증가되는 것으로 알려져 있다. 따라서 입을 항상 벌리는 습관이 있는 경우에 구강이 건조해지면 구취가 증가할 수 있다. 구강양치액의 알코올 농도은 0~27%정도에 해당한다.  The use of mouthwashes containing high concentrations of ethanol weakens the surface of the resin series, which is a dental restoration, and has been reported to cause dry mouth. If the saliva secretion is severely reduced by the use of alcohol, dry mouth is caused. It usually occurs when there is a disease involving the salivary glands or when there is a disease such as Sjogren's syndrome. In this case, the density of saliva microorganisms is increased and swallowing (swallowing) is reduced, so that the time to stay in the oral cavity is known to increase the generation of substances causing bad breath. Therefore, if you have a habit of always opening your mouth, dry mouth can increase bad breath. The alcohol concentration of the oral solution is about 0-27%.

또한 클로르헥시딘이 포함된 구강양치액을 장기간 사용하면 정상적인 구강세균총을 파괴하여 구내염 등의 원인을 제공하게 된다. 따라서 본 양치액은 알콜 및 클로르헥시딘 등의 성분이 포함되지 않은 천연의 구강세정제가 국민의 구강건강을 위하여 필요하다.  In addition, long-term use of chlorhexidine-containing oral solution will destroy the normal oral flora and provide a cause for stomatitis. Therefore, the toothpaste is a natural oral cleanser that does not contain alcohol and chlorhexidine, etc. is necessary for the oral health of the people.

국화는 해열, 해독, 진통 및 소염제의 효능을 가지고 있다. 따라서 감기, 발열, 두통, 어지러움, 귀울림 및 눈병 등에 효과가 있다. 또한 비타민이 풍부하여 겨울철 감기 예방에 특효가 있으며, 기관지 계통을 깨끗하게 해주어 기침, 천식, 가래해소, 후두염에 효과를 볼 수 있다. 불면증에도 효과가 좋아 우려낸 잎으로 베개를 만들어 사용하면 더 큰 효과를 볼 수 있다. 머리를 맑게 해주고 어지러움을 없애주고 지속적으로 마시면 노화방지에도 좋다.   Chrysanthemum has the efficacy of antipyretic, detoxification, analgesic and anti-inflammatory agents. Therefore, it is effective for colds, fever, headache, dizziness, tinnitus and eye disease. In addition, it is rich in vitamins and is effective in preventing colds in winter, and cleans the bronchial system so that it can be effective for coughing, asthma, sputum and laryngitis. It is also effective for insomnia, so if you use a pillow made of leaves you can see a bigger effect. Clearing your hair, getting rid of dizziness, and drinking continuously can help prevent aging.

곽향의 주요성분은 트리메칠싸이크로핵산, 카보시릭산 및 아카세틴 등이다. 곽향은 피부 진균, 대장균, 이질균, 폐렴균 및 용혈성연쇄상구균 억제에 효과가 있다. 또한 위액분비 촉진작용 등이 있어 소화불량, 설사 등의 증상이 있는 감기에 효과가 있다. 향이 좋고 약효성분이 많아, 육류, 해물요리, 매운탕 등에 사용하면 생선특유의 비린내를 없애주므로 용도가 다양하게 이용된다.   The main constituents of Kwak Hyang are trimethylcyclonucleic acid, carbosilic acid and acecetin. It is effective in suppressing skin fungi, Escherichia coli, dysentery, pneumococci and hemolytic streptococci. In addition, the secretion of gastric juice secretion, such as indigestion, diarrhea and other symptoms, such as cold is effective. It has good fragrance and many active ingredients, and it can be used for meat, seafood, and Maeuntang so it removes fishy fishy smell.

형개는 꿀풀과에 속하는 일년생 초본으로서 줄기는 네모나고 전초에 잔털이 밀생하며 잎은 깃 모양으로 다섯 갈래로 깊이 갈라져 있다. 갈라진 잎은 선형 또는 피침형으로 가장자리에는 톱니가 없고 밋밋하여 잎 끝은 뭉툭하다. 성분은 정유가 대부분으로 멘톨(menthol), 리모넨(limonene)을 함유하고 있으며 특유한 향기를 가지고 있다. 구풍해열제로 중풍, 감기, 인후염, 종기 등에 사용한다.   Hyungae is an annual herb belonging to the Lamiaceae family. The stem is square, the outpost is dense with fine hairs, and the leaves are pinnate and divided into five branches. Split leaves are linear or lanceolate, without sawtooth at edge, flat and blunt with leaf tip. Most of the essential oils contain menthol and limonene and have a distinctive scent. It is used as antipyretic antipyretic agent for stroke, cold, sore throat and boil.

국화, 곽향 및 형개에 대한 효과를 정리하면, 국화는 진통, 소염제 효과가 있다. 곽향은 피부 진균, 대장균, 이질균, 폐렴균 및 용혈성연쇄상구균 억제에 효과가 있으며, 고기비린내 제거용으로 사용한다. 형개는 성분은 정유가 대부분으로 멘톨(menthol), 리모넨(limonene)을 함유하고 있으며 특유한 향기를 가지고 있다. 위의 세가지 성분에 우식예방효과가 있는 불소, 계면활성제, 향료 및 감미료를 첨가한다. 이 양치액은 진통, 소염, 균성장억제 및 구취제거 효과를 가지는 천연의 구강양치액이다.   Summarizing the effects on chrysanthemums, eccentricity and mold opening, chrysanthemum has analgesic and anti-inflammatory effects. Kwak Hyang is effective in inhibiting skin fungi, E. coli, dysentery, pneumococci and hemolytic streptococci, and is used for meaty odor removal. The type of ingredient is menthol, limonene, and most of the essential oils have a distinctive scent. To these three components, add fluoride, surfactant, fragrance and sweetener, which have caries prevention effect. This fern is a natural oral fern having analgesic, anti-inflammatory, fungal growth inhibition and bad breath removal effects.

본 발명에 사용된 한약재의 구강에서의 효과는 항염증작용, 구취억제 작용을 들 수 있다. 더불어 보조적으로 첨가되는 불소는 치아의 항우식작용을 가진다. 계면활성제는 치면세균막의 침착을 억제한다. 향료 및 감미료는 양치액의 맛을 조절하는데 사용한다.  The oral effect of the herbal medicine used in the present invention may be anti-inflammatory action, bad breath inhibitory action. In addition, supplementary fluoride has anti-caries effect on teeth. Surfactants inhibit the deposition of dental plaques. Flavors and sweeteners are used to control the taste of the fern.

본 발명은 구강건강에 필요한 염증완화 및 구취제거 효과를 천연한약 성분을 이용한 것이다. 천연한약 성분은 인체에 안전하며 본 제제가 구강건강에 효과가 있어 국민 구강건강 증진에 기여하고자 하는 것이다.    The present invention uses natural herbal ingredients to reduce inflammation and remove bad breath. Natural herbal ingredients are safe for the human body, and this preparation is effective for oral health.

상기 목적을 달성하기 위하여 국화, 곽향 및 형개를 추출하여 혼합한다. 이 용액에 불소성분, 계면활성제, 향료 및 당류를 첨가하여 천연의 구강양치액을 제조하고자 한다. 불소성분으로는 불화나트륨을 1,000ppm 함유하도록 한다. 계면활성제 성분으로는 소디움 라우릴 설페이트를 사용한다.    In order to achieve the above purpose, the chrysanthemum, eccentricity and mold opening are extracted and mixed. To prepare a natural mouthwash by adding a fluorine component, surfactant, fragrance and sugar to this solution. The fluorine component should contain 1,000 ppm of sodium fluoride. Sodium lauryl sulfate is used as the surfactant component.

한약재를 적당한 크기로 파쇄하여 추출기를 이용하여 추출한다. 여기에 소디움 플루오르, 소디움 라우릴 설페이트, 향료 및 당류를 첨가하여 제조한다. 구강내 염증제거와 구취제거 효과를 가져온다.The medicinal herb is crushed to a suitable size and extracted using an extractor. It is prepared by adding sodium fluorine, sodium lauryl sulfate, perfume and sugars. Inflammation and bad breath removal effect in the mouth.

본 발명에 의한 양치액은 천연의 한약재를 사용하여 인체에 안전하고 구강염증, 구취 등 구강위생에 효과가 좋다. 장기간 사용하여도 구강건조증이나, 상재균총에 억제에 의한 미생물교대증 등의 이상을 보이지 않고 구강위생에 기여한다.The dentifrice according to the present invention is safe for the human body using natural herbal medicine and is effective for oral hygiene such as oral inflammation and bad breath. Long-term use contributes to oral hygiene without showing abnormalities such as dry mouth or microbial shift caused by inhibition of the flora.

국화추출액, 곽향추출액, 형개추출액, 불화나트륨, 계면활성제 및 향료 배합Chrysanthemum Extract, Quarantine Extract, Mold Open Extract, Sodium Fluoride, Surfactant and Flavoring Formulation

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국화, 곽향 및 형개 추출물을 이용한 구강양치액Oral Mouthwash Using Chrysanthemum, Kwakhyang and Hungae Extracts
KR1020080100961A 2008-10-15 2008-10-15 Mouthwash which include the chrysanthemum, germander and japonica extract KR20100041922A (en)

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KR101506382B1 (en) * 2013-01-18 2015-03-30 주식회사 한국코러스제약 Composition of foaming tablet
WO2016117933A1 (en) * 2015-01-22 2016-07-28 조선대학교산학협력단 Oral composition containing camellia leaf extract, and preparation method therefor
KR20190043997A (en) * 2017-10-19 2019-04-29 종근당건강 주식회사 Composition for prevention or treatment respiratory diseases comprising combination extracts of Chrysanthemum morifolium Ramatuelle and Scutellaria baicalensis as an active ingredient
KR20220113013A (en) * 2021-02-05 2022-08-12 충남대학교산학협력단 Antibacterial sticker comprising of Chrysanthemum morifolium flower extract

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101506382B1 (en) * 2013-01-18 2015-03-30 주식회사 한국코러스제약 Composition of foaming tablet
WO2016117933A1 (en) * 2015-01-22 2016-07-28 조선대학교산학협력단 Oral composition containing camellia leaf extract, and preparation method therefor
KR20160090708A (en) * 2015-01-22 2016-08-01 조선대학교산학협력단 Composition for mouth comprising camellia japonica l leaf extract and manufacturing method thereof
KR20190043997A (en) * 2017-10-19 2019-04-29 종근당건강 주식회사 Composition for prevention or treatment respiratory diseases comprising combination extracts of Chrysanthemum morifolium Ramatuelle and Scutellaria baicalensis as an active ingredient
KR20220113013A (en) * 2021-02-05 2022-08-12 충남대학교산학협력단 Antibacterial sticker comprising of Chrysanthemum morifolium flower extract

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