CN107320401A - A kind of mouthwash of pre- anti-caries and preparation method thereof - Google Patents
A kind of mouthwash of pre- anti-caries and preparation method thereof Download PDFInfo
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- CN107320401A CN107320401A CN201710711079.2A CN201710711079A CN107320401A CN 107320401 A CN107320401 A CN 107320401A CN 201710711079 A CN201710711079 A CN 201710711079A CN 107320401 A CN107320401 A CN 107320401A
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- caries
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a kind of mouthwash of pre- anti-caries and preparation method thereof, the mouthwash is comprised the following raw materials by weight percent：20~40% plant extraction liquid I, 5~15% rose, 10~20% sweet osmanthus hydrosol, 10~15% chamomile hydrosol, 0.5~1% Crodaret, 0.5~1% lauryl sodium sulfate, surplus is water；Wherein, the extracting method of the plant extraction liquid I is as follows：The dry raw material that will be made up of following percentage by weight：25~55% purple perillas, 18~38% peppermints, 5~25% honeysuckles, 4~15% cordate houttuynias, are placed in extractor, with mass ratio 1:10~1:20 ratio, adds deionized water, in 60~80 DEG C, extracts 1~3h, and extract solution filtering is concentrated into the volume of stoste 1/2~1/4, obtains plant extraction liquid I.The present invention is according to above-mentioned formula reasonable compatibility, without any preservative, and the effect with good anti-inflammation, cleaning oral cavity can be used for a long time, for preventing or treating carious tooth.
Description
Technical field
The invention belongs to oral health care field, mouthwash and its preparation more particularly, to a kind of pre- anti-caries
Method.
Background technology
Carious tooth is bacteriosis, the fifties in last century it has been recognized that without microorganism just without dental caries, ecology
Theory thinks that the bacterium relevant with dental caries generation is all oral cavity normal microflora.Due to part, whole body and (or) food
The change of thing factor, can cause the change for causing oral cavity ecological environment, so that normal bacteria and the physiological group asked of host
Pathologic combination is changed into conjunction, and oral cavity life reads equilibrium conversion for ecological disturbance, and normal bacteria turns into conditioned pathogen and causes dental caries
Disease.Therefore it can be with secondary pulpitis and periapical inflammation, or even can cause alveolar bone and inflammation of jaws etc., causes the whole for suffering from tooth
Destruction；The scabies secondary infection of carious tooth can form focus, and bacteriotoxin is expanded by means of blood circulation to whole body, induce systemic disease.
As can be seen here, dental caries are great to the health effect of people and harm.China's Third National Healthy adolescent investigation
As a result show, publicize and educate by oral health for many years, obtained entirely by the way of brushing teeth and using toothpaste with fluoride
The extensive approval of society.But this time investigation result is also shown, it is high that crowd's caries prevalence rates of the multiple age brackets of China is in comparison
Level.In China, dental caries incidence average out to 44.8%, children are then up to 70% or so.United according to Stomatology Clinic
Meter, the clients due to dental caries and its complication account for the 60% of outpatient's sum, the tooth pulled out by these reasons is accounted for
The half of extraction sum.This shows, although most people have been able to accomplish to brush teeth daily, but could not still control the hair of dental caries
It is raw.
With the development and the continuous improvement of living standard of economic society, the oral health consciousness of people is greatly enhanced, mouth
Chamber care product general layout upgrades to toothpaste gradually via initial toothpaste " dominance ", dental floss, tooth patch, mouthwash, electronic
The group of the products such as toothbrush fights.Consumption purpose also develops into the U.S. tooth of shield tooth, cleaning oral cavity by single cleaning tooth.In supermarket
Before the shelf of personal-care supplies, consumer is easy in toothpaste adjacent to finding what external daily use chemicals giant produced, and packaging is fastidious, color
Pool is vivid, for a kind of product of oral cavity cleaning and nursing, here it is mouthwash.
The main composition containing triclosan or metronidazole, Tinidazole or hydrogen peroxide or iodine solution etc. of mouthwash conventional at present, this
Class mouthwash is respectively provided with sterilization or bacteriostasis, but be not suitable for being used as common oral care well.U.S.'s food and medicine
The mouthwash of product management board certification is included containing essential oil and containing the class of chlorohexidene two, and the latter, which is used for a long time, easily causes dental calculus formation, facing
Coloring and the sense of taste change.The mouthwash of class containing essential oil has permeability strong, is not in gingival discoloration after use, flora imbalance, secondary
Infection etc., though containing alcoholic ingredient, harmless to oral cavity partial, such mouthwash main function is fresh breath, to preventing and treating dental caries
The mouth disease effect such as disease is not notable.
The content of the invention
For above-mentioned deficiency of the prior art, the invention provides a kind of mouthwash of pre- anti-caries and its preparation side
Method, preparation technology is simple, and good effect has no side effect safely.
The above-mentioned purpose of the present invention is achieved by the following technical programs.
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：20~40% plant extraction liquid
I, 5~15% rose, 10~20% sweet osmanthus hydrosol, 10~15% chamomile hydrosol, 0.5~1% polyoxy second
Alkene rilanit special, 0.5~1% lauryl sodium sulfate, surplus is water；Wherein, the extracting method of the plant extraction liquid I
It is as follows：The dry raw material that will be made up of following percentage by weight：25~55% purple perillas, 18~38% peppermints, 5~25% honeysuckles, 4
~15% cordate houttuynia, is placed in extractor, with mass ratio 1:10~1:20 ratio, adds deionized water, in 60~80 DEG C, carries
1~3h is taken, extract solution filtering is concentrated into the volume of stoste 1/2~1/4, obtains plant extraction liquid I.
Preferably, described plant extraction liquid I, is made up of the dry raw material of following percentage by weight：32~48% purple perillas, 20
~35% peppermint, 10~22% honeysuckles, 8~12% cordate houttuynias.
Preferably, described plant extraction liquid I extracting method is as follows：The dry original that will be made up of following percentage by weight
Material：32% purple perilla, 35% peppermint, 22% honeysuckle, 11% cordate houttuynia, are placed in extractor, with mass ratio 1:10 ratio, plus
Enter deionized water, in 60 DEG C, extract 1h, extract solution filtering is concentrated into the volume of stoste 1/2, obtains plant extraction liquid I.
Preferably, described plant extraction liquid I extracting method is as follows：The dry original that will be made up of following percentage by weight
Material：40% purple perilla, 30% peppermint, 20% honeysuckle, 10% cordate houttuynia, are placed in extractor, with mass ratio 1:15 ratio, plus
Enter deionized water, in 70 DEG C, extract 2h, extract solution filtering is concentrated into the volume of stoste 1/3, obtains plant extraction liquid I.
Preferably, a kind of mouthwash of described pre- anti-caries, is comprised the following raw materials by weight percent：30% plant
Thing extract solution I, 10% rose, 15% sweet osmanthus hydrosol, 12% chamomile hydrosol, 0.8% it is polyethylene glycol hydrogenated
Castor oil, 0.8% lauryl sodium sulfate, surplus is water.
The present invention also provides the preparation method of the mouthwash of described pre- anti-caries, and the key step of its preparation method is such as
Under：
S1. the percentage by weight is pressed by plant extraction liquid I, rose, sweet osmanthus hydrosol, chamomile hydrosol, polyoxy second
Alkene rilanit special, lauryl sodium sulfate and water, which are placed in agitator tank, is warming up to 60~80 DEG C, is incubated 20~40min, makes solid
Body material is completely dissolved, and obtains mixed solution A；
S2. the mixed solution A is cooled to 40 DEG C, pH is to 5.5~6.5 for regulation, produces mouthwash of the present invention.
Application method：Keep sooner or later conventional daily to brush teeth, and be maintained at three using the mouthwash after the meal, you can play
Clean oral cavity, the effect of pre- anti-caries.
Rose：Sweet, slight bitter, temperature, promoting qi circulation and removing obstruction in the collateral, and blood, analgesic, this product smell delicate fragrance are apt to energy dispersing stagnated hepatoqi and solve strongly fragrant,
With antibacterial, the characteristic of anti-inflammatory, it can help to eliminate bacterial halitosis, fresh breath helps to alleviate oral cavity pain.
Sweet osmanthus：Yellowish white, fragrance is pungent, temperature, the broken knot of cold dispelling, for having a toothache, cough and phlegm.Releive throat, improve many
Phlegm, cough symptom, control duodenal ulcer, and halitosis, vision are failed to understand.
Chamomile：Mildly bitter flavor, Gan Xiang, improving eyesight, move back irascibility, can invigorate, refresh oneself.Expelling phlegm and arresting coughing, can effectively alleviate branch
Tracheitis and asthma, the headache that can releive, antimigraine or courbature caused by flu are helpful to calm nerves.And Jiao can be treated
Consider and the nervous indigestion caused, and to neuralgia, toothache has all been benefited.
Purple perilla：Nature and flavor are pungent, tepor, nontoxic, during promoting the circulation of qi is wide, sending down abnormally ascending dissolving phlegm, moistening lung of only coughing, dissolving phlegm profit lung, and blood, middle benefit gas,
Analgesic, Dingchuan is antiabortive.
Peppermint：Containing menthol, can fresh breath and with a variety of property of medicine, also with antisepsis and sterilization, diuresis, resolving sputum, strong
Stomach and it is aid digestion the effects such as, be one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls headache, throat, gum and swells and ache
Deng disease.External application can control neuralgia, pruitus, fash and eczema etc..
Honeysuckle：It is sweet, it is cold in nature, containing pharmacological components such as chlorogenic acid, cyanidenon glycosides, to hemolytic streptococcus,
The various pathogens such as Staphylococcus aureus and infection of the upper respiratory tract Causative virus etc. have stronger restraint；Kind removing summer-heat blood poison, is used
, in addition can also strengthen immunity, effect of qi-restoratives treatment wind in various febrile diseases.
Cordate houttuynia：Cold nature, bitter is clearing heat and detoxicating, can strengthen WBC phagocytic activity, improves serum properdin, improves
Immunity of organisms, the treatment to venereal infection is had great significance, and a kind of yellow oil is raised in cordate houttuynia, to various micro-
Biological (especially saccharomycete and mould) presses down agent effect to have, streptococcus, golden yellow muscle grape coccus to hemolytic, influenza bar
Bacterium, micrococcus catarrhalis, lung service magnetic have obvious inhibitory action.
Compared with prior art, beneficial effect of the present invention is：(1) a kind of pre- anti-caries that the present invention is provided are gargled
Water, prescription proportion optimizing is carried out by the active ingredient of contained Chinese medical extract, and formula is gentle, makees with good anti-inflammation
With, by the synergy of each material effective component, mild in medicine property and, while safely and effectively cleaning oral cavity, kill except microorganism
And tartar, oral peculiar smell is eliminated, and product of the present invention is free of any preservative in itself, can be used for a long time, for preventing or controlling
Treat carious tooth or canker sore.(2) a kind of preparation method of the mouthwash for pre- anti-caries that the present invention is provided is simple and easy to apply, uses peace
It is complete convenient.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.Unless stated otherwise, the reagent of the invention used, method and apparatus is the art conventional reagent, methods
And equipment.
A kind of preparation method of the mouthwash of pre- anti-caries described in following embodiments 1~5, the main step of its preparation method
It is rapid as follows：
S1. the percentage by weight is pressed by plant extraction liquid I, rose, sweet osmanthus hydrosol, chamomile hydrosol, polyoxy second
Alkene rilanit special, lauryl sodium sulfate and water, which are placed in agitator tank, is warming up to 60~80 DEG C, is incubated 20~40min, makes solid
Body material is completely dissolved, and obtains mixed solution A；
S2. the mixed solution A is cooled to 40 DEG C, pH is to 5.5~6.5 for regulation, produces mouthwash of the present invention.
Embodiment 1
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：30% plant extraction liquid I,
10% rose, 15% sweet osmanthus hydrosol, 12% chamomile hydrosol, 0.8% Crodaret,
0.8% lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take following weight hundred
Divide the dry raw material of ratio：40% purple perilla, 30% peppermint, 20% honeysuckle, 10% cordate houttuynia, are placed in extractor, with mass ratio 1:
15 ratio, adds deionized water, in 70 DEG C, extracts 2h, and extract solution filtering is concentrated into the volume of stoste 1/3, obtains plant extract
Liquid I.
Embodiment 2
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：20% plant extraction liquid I, 5%
Rose, 10% sweet osmanthus hydrosol, 10% chamomile hydrosol, 0.5% Crodaret, 0.5%
Lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take the dry of following percentage by weight
Raw material：32% purple perilla, 35% peppermint, 22% honeysuckle, 11% cordate houttuynia, are placed in extractor, with mass ratio 1:10 ratio,
Deionized water is added, in 60 DEG C, 1h is extracted, extract solution filtering is concentrated into the volume of stoste 1/2, obtains plant extraction liquid I.
Embodiment 3
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：40% plant extraction liquid I,
15% rose, 20% sweet osmanthus hydrosol, 15% chamomile hydrosol, 1% Crodaret, 1%
Lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take the dry of following percentage by weight
Raw material：48% purple perilla, 20% peppermint, 20% honeysuckle, 12% cordate houttuynia, are placed in extractor, with mass ratio 1:20 ratio,
Deionized water is added, in 80 DEG C, 3h is extracted, extract solution filtering is concentrated into the volume of stoste 1/4, obtains plant extraction liquid I.
Embodiment 4
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：40% plant extraction liquid I,
15% rose, 20% sweet osmanthus hydrosol, 15% chamomile hydrosol, 1% Crodaret, 1%
Lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take the dry of following percentage by weight
Raw material：25% purple perilla, 38% peppermint, 25% honeysuckle, 12% cordate houttuynia, are placed in extractor, with mass ratio 1:10 ratio,
Deionized water is added, in 60 DEG C, 1h is extracted, extract solution filtering is concentrated into the volume of stoste 1/2, obtains plant extraction liquid I.
Embodiment 5
A kind of mouthwash of pre- anti-caries, is comprised the following raw materials by weight percent：30% plant extraction liquid I,
10% rose, 15% sweet osmanthus hydrosol, 12% chamomile hydrosol, 0.8% Crodaret,
0.8% lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take following weight hundred
Divide the dry raw material of ratio：55% purple perilla, 36% peppermint, 5% honeysuckle, 4% cordate houttuynia, are placed in extractor, with mass ratio 1:20
Ratio, add deionized water, in 80 DEG C, extract 3h, extract solution filtering is concentrated into the volume of stoste 1/4, obtains plant extraction liquid
I。
Comparative example 1
The present embodiment formula is same as Example 1, and difference is a kind of system of the mouthwash of described pre- anti-caries
Preparation Method, the key step of its preparation method is as follows：
S1. the percentage by weight is pressed by plant extraction liquid I, rose, sweet osmanthus hydrosol, chamomile hydrosol, polyoxy second
Alkene rilanit special, lauryl sodium sulfate and water, which are placed in agitator tank, is warming up to 100 DEG C, is incubated 15min, makes solid material complete
Fully dissolved, obtains mixed solution A.
S2. gained mixed solution in A is cooled to 40 DEG C, pH is to 5.5~6.5 for regulation, produces mouthwash of the present invention.
Comparative example 2
This comparative example is different from the formula of embodiment 1, is specially to be made up of the raw material of following percentage by weight：15% plant
Thing extract solution I, 5% rose, 8% sweet osmanthus hydrosol, 10% chamomile hydrosol, 0.5% polyethylene glycol hydrogenated castor
Sesame oil, 1.2% lauryl sodium sulfate, surplus is water；Plant extraction liquid I therein, its extracting method is as follows：Take following weight
Measure the dry raw material of percentage：15% purple perilla, 45% peppermint, 28% honeysuckle, 12% cordate houttuynia, are placed in extractor, with quality
Than 1:10 ratio, adds deionized water, in 60 DEG C, extracts 1h, and extract solution filtering is concentrated into the volume of stoste 1/2, obtains plant
Extract solution I.
Application examples 1
Totally 700 children are chosen from kindergarten, man, each 350 of female are divided into 7 groups, every group 100.Age (3.5 ±
0.5) year, caries prevalence rate is 28.8%, the clinical data such as sex, age, caries prevalence rate of these children comparing difference without statistics anticipate
Justice (P>0.05), with comparativity.Oral hygiene inspection is carried out to all children before treatment, guiding children is brushed teeth, cleaning of gargling
Oral cavity and bacterial plaque of tooth surface and soft dirt.With 7 groups of children of relief respectively using the pre- preventing decayed tooth of embodiment 1,2,3,4,5 and comparative example 1,2
The mouthwash of tooth.Each 10~15ml containing mouthwash, continues not brush teeth in 1~2min, 30min, drinks water or diet, 1 week 2
It is secondary, continuous 4 weeks, continue same method after half a year and use Chinese medicine mouth wash.7 groups of children are carried out after treatment end 2 years by a definite date with
Investigation is visited, caries in primary teeth situation is recorded.7 groups of children's caries prevalence rates are observed, 1 is the results are shown in Table.
Treatment results：As shown in table 1, the embodiment of the present invention 1, the mouthwash formula of 2,3,4,5 pre- anti-caries is in prevention
There is significant effect in terms of carious tooth；And though the mouthwash formula of the pre- anti-caries of comparative example 1,2 has necessarily in terms of pre- anti-caries
Curative effect, but its effective percentage is significantly lower than the embodiment of the present invention.Illustrate that the mouthwash of pre- anti-caries of the invention passes through between each component
Collaboration compounding, the effect of significant pre- anti-caries can be played.
Effect (%) of the mouthwash formula of the different pre- anti-caries of table 1 in terms of pre- anti-caries
Application examples 2
Totally 300 children are chosen from kindergarten, man, each 150 of female are divided into 3 groups, every group 100.Age (3.5 ±
0.5) year, caries prevalence rate is 28.8%, the clinical data such as sex, age, caries prevalence rate of these children comparing difference without statistics anticipate
Justice (P>0.05), with comparativity.Oral hygiene inspection is carried out to 3 groups of children before treatment, guiding children is brushed teeth, cleaning mouth of gargling
Chamber and bacterial plaque of tooth surface and soft dirt.Control group receives local fluoro-containing coating prophylactic treatment, and concrete operation step is：Wiped with rayon balls
Facing is wiped, by 0.25ml fluoro-containing coatings solution [Pulpdent companies produce, and state's food medicine prison tool (enters) word 2012 the 2630060th]
Squeeze in the supporting amount paperboard of product, then after being dipped with supporting swab stick, according to each facing of upper tooth order even spread after first lower tooth, so
After the 1~2min that remains silent make material solidification, advising in 30min can not drink water, gargles or feed, and that night can not brush teeth, after 6 months again
Fluoride in caries prevention is applied using local 1 time.Experimental group is gargled using the Chinese medicine mouth wash of embodiment 1, comparative example group using the Chinese medicine of comparative example 2
Saliva, each 10~15ml containing mouthwash, continues not brush teeth in 1~2min, 30min, drinks water or diet, 1 week 2 times, continuous 4
Continue same method after week, half a year and use Chinese medicine mouth wash.After treatment end 3 groups of children are carried out with 2 years follow-up investigations by a definite date, note
Record caries in primary teeth situation.3 groups of children's caries prevalence rates, caries of primary teeth face (DMFS), the equal index of conspicuousness dental caries (SIC) are observed, is as a result divided
2, table 3, table 4 are not shown in Table.
Caries prevalence rate situation (%) before and after 2 three groups of children's preventing and treatings of table
Tooth dental caries face (DMFS) situation of change before and after 3 three groups of children's preventing and treatings of table
Conspicuousness dental caries equal index (SIC) situation of change before and after 4 three groups of children's preventing and treatings of table
Found through clinical investigation, 1 year and 2 years after preventing and treating, 3 groups of children's caries prevalence rates, caries of primary teeth faces (DMFS), conspicuousness dental caries
Equal index (SIC) is raised before relatively preventing and treating, but experimental group is significantly lower than control group and comparative example group, illustrates the present invention is provided one
The active ingredient for planting the Chinese medical extract contained by the mouthwash of pre- anti-caries carries out prescription proportion optimizing, and formula is gentle, with more
Superior antibacterial and anti-inflammation functions, by the synergy of each material effective component, mild in medicine property and in safely and effectively cleaning oral cavity
Meanwhile, kill except microorganism and tartar, eliminate oral peculiar smell, can be used for a long time, for preventing or treating carious tooth or canker sore.
It is described above, it is only the explanation embodiment of the present invention, formal and substantial limitation not any to the present invention,
It should be pointed out that for those skilled in the art, on the premise of the inventive method is not departed from, that makes some changes
Enter and supplement and also should be regarded as protection scope of the present invention.All those skilled in the art, do not depart from spirit of the invention and
In the case of scope, a little change, modification and the equivalent variations developed made using disclosed above technology contents are
The equivalent embodiment of the present invention；Meanwhile, any equivalent variations that all substantial technologicals according to the present invention are done to above-described embodiment
Change, modification with develop, still fall within protection scope of the present invention.
Claims (6)
1. a kind of mouthwash of pre- anti-caries, it is characterised in that comprise the following raw materials by weight percent：20~40% plant
Thing extract solution I, 5~15% rose, 10~20% sweet osmanthus hydrosol, 10~15% chamomile hydrosol, 0.5~1%
Crodaret, 0.5~1% lauryl sodium sulfate, surplus is water；Wherein, the plant extraction liquid I
Extracting method is as follows：The dry raw material that will be made up of following percentage by weight：25~55% purple perillas, 18~38% peppermints, 5~25%
Honeysuckle, 4~15% cordate houttuynias, are placed in extractor, with mass ratio 1:10~1:20 ratio, adds deionized water, in 60
~80 DEG C, 1~3h is extracted, extract solution filtering is concentrated into the volume of stoste 1/2~1/4, obtains plant extraction liquid I.
2. a kind of mouthwash of pre- anti-caries according to claim 1, it is characterised in that described plant extraction liquid I, by
The dry raw material composition of following percentage by weight：32~48% purple perillas, 20~35% peppermints, 10~22% honeysuckles, 8~12% fishes
Raw meat grass.
3. the mouthwash of a kind of pre- anti-caries according to claim 1, it is characterised in that described plant extraction liquid I's
Extracting method is as follows：The dry raw material that will be made up of following percentage by weight：32% purple perilla, 35% peppermint, 22% honeysuckle, 11%
Cordate houttuynia, is placed in extractor, with mass ratio 1:10 ratio, adds deionized water, in 60 DEG C, extracts 1h, and extract solution is filtered,
The volume of stoste 1/2 is concentrated into, plant extraction liquid I is obtained.
4. the mouthwash of a kind of pre- anti-caries according to claim 1, it is characterised in that described plant extraction liquid I's
Extracting method is as follows：The dry raw material that will be made up of following percentage by weight：40% purple perilla, 30% peppermint, 20% honeysuckle, 10%
Cordate houttuynia, is placed in extractor, with mass ratio 1:15 ratio, adds deionized water, in 70 DEG C, extracts 2h, and extract solution is filtered,
The volume of stoste 1/3 is concentrated into, plant extraction liquid I is obtained.
5. the mouthwash of a kind of pre- anti-caries according to claim 1, it is characterised in that by the original of following percentage by weight
Material composition：30% plant extraction liquid I, 10% rose, 15% sweet osmanthus hydrosol, 12% chamomile hydrosol, 0.8%
Crodaret, 0.8% lauryl sodium sulfate, surplus is water.
6. a kind of preparation method of the mouthwash of pre- anti-caries any one of claim 1 to 5, it is characterised in that its
Preparation method is as follows：
S1. the percentage by weight is pressed by plant extraction liquid I, rose, sweet osmanthus hydrosol, chamomile hydrosol, polyoxyethylene hydrogen
Change castor oil, lauryl sodium sulfate and water, which are placed in agitator tank, is warming up to 60~80 DEG C, is incubated 20~40min, makes solids
Material is completely dissolved, and obtains mixed solution A；
S2. the mixed solution A is cooled to 40 DEG C, pH is to 5.5~6.5 for regulation, produces mouthwash of the present invention.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112641873A (en) * | 2019-10-12 | 2021-04-13 | 福建爱洁丽日化有限公司 | A collutory containing folium Perillae for preventing dental caries |
| CN113230165A (en) * | 2021-04-02 | 2021-08-10 | 北京圣永制药有限公司 | A collutory containing marrubium vulgare extract with antiinflammatory and antibacterial effects |
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| CN113230165A (en) * | 2021-04-02 | 2021-08-10 | 北京圣永制药有限公司 | A collutory containing marrubium vulgare extract with antiinflammatory and antibacterial effects |
| CN113230165B (en) * | 2021-04-02 | 2023-03-17 | 北京圣永制药有限公司 | A collutory containing marrubium vulgare extract with antiinflammatory and antibacterial effects |
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