CN112641873A - A collutory containing folium Perillae for preventing dental caries - Google Patents

A collutory containing folium Perillae for preventing dental caries Download PDF

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Publication number
CN112641873A
CN112641873A CN201910969763.XA CN201910969763A CN112641873A CN 112641873 A CN112641873 A CN 112641873A CN 201910969763 A CN201910969763 A CN 201910969763A CN 112641873 A CN112641873 A CN 112641873A
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China
Prior art keywords
parts
orange peel
dried orange
almond
rhizoma
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Pending
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CN201910969763.XA
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Chinese (zh)
Inventor
陈万金
蔡丽萍
黄强
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Fujian Azalli Chemicals Co ltd
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Fujian Azalli Chemicals Co ltd
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Priority to CN201910969763.XA priority Critical patent/CN112641873A/en
Publication of CN112641873A publication Critical patent/CN112641873A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Abstract

The invention discloses a perilla leaf-containing anti-caries mouthwash, which comprises the following raw materials in parts by weight: 20-40 parts of perilla leaf, 10-25 parts of mint leaf, 10-20 parts of honeysuckle, 10-20 parts of allium macrostemon, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of radix ophiopogonis, 5-10 parts of almond, 3-5 parts of radix peucedani, 5-10 parts of rhizoma cyperi and 3-5 parts of dried orange peel. The caries preventing mouthwash containing perilla leaf can play an antibacterial role through the perilla leaf extract contained in the caries preventing mouthwash, can be used with almond and peucedanum root for treating cold and has the functions of detoxifying, calming and relieving cough, can be used with rhizoma cyperi and dried orange peel for treating symptoms of qi stagnation of spleen and stomach, chest distress and vomiting, and can be used with the functions of nourishing yin and lowering fire of rhizoma anemarrhenae, the functions of moistening lung and clearing away heart-fire and purging heat and promoting the production of body fluid of radix ophiopogonis, the functions of activating yang and dissipating stagnation and promoting qi circulation and removing stagnation of allium macrostemon and can be matched with the effects of the perilla leaf extract, the rhizoma cyperi and the dried orange peel for further reducing the vomit symptom of a user.

Description

A collutory containing folium Perillae for preventing dental caries
Technical Field
The invention relates to the technical field of oral cleaning and nursing, in particular to an anti-caries mouthwash containing perilla leaves.
Background
The mouthwash is one of the modes of cleaning oral health, generally can control bacterial plaque on the basis of effectively brushing teeth, and can penetrate into various parts of the oral cavity, reduce bacteria and bacterial plaque causing halitosis, and improve gum health.
The history of mouth washing is longer than that of tooth brushing, although the use of the toothbrush and the dental floss is an effective measure for removing the dental plaque, the method for controlling the dental plaque is difficult to educate and master, but also is tedious and time-consuming, is difficult to be completed especially for patients with physical and mental disabilities and difficult to be adopted by persons without motivation, the gargle is an ideal substitute for the people, and practice proves that the gargle is convenient to use, easy to master, practical and feasible, is suitable for daily oral care at home and is also suitable for work and business trip, especially those who seek high-quality life, want to refresh their breath by various means, the mouthwash can achieve this effect in a short time, the mouthwash has bactericidal and bacteriostatic effects, after the characteristics of dental plaque biomembranes are destroyed by tooth brushing, the effect is better, and the dental plaque can be more effectively controlled by using the mouthwash after tooth brushing than by tooth brushing alone.
However, although all the existing mouthwashes have the functions of diminishing inflammation and sterilizing, the existing mouthwashes have poor curative effects on symptoms such as retching and accompanied cough and have poor functionality.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides the caries prevention mouthwash containing the perilla leaves, which solves the problems of poor curative effect and poor functionality on symptoms such as retching and cough although the existing mouthwash has the functions of diminishing inflammation and sterilizing.
In order to achieve the purpose, the invention provides the following technical scheme: an anticariogenic mouthwash containing perilla leaves comprises the following raw materials in parts by weight: 20-40 parts of perilla leaf, 10-25 parts of mint leaf, 10-20 parts of honeysuckle, 10-20 parts of allium macrostemon, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of radix ophiopogonis, 5-10 parts of almond, 3-5 parts of radix peucedani, 5-10 parts of rhizoma cyperi and 3-5 parts of dried orange peel.
An anticariogenic mouthwash containing perilla leaves comprises the following preparation steps:
s1, taking 20-40 parts of perilla leaves, 10-25 parts of mint leaves and 10-20 parts of honeysuckle, adding 100 parts of distilled water and 150 parts of distilled water, soaking for 1.5 hours, respectively crushing, grinding and stirring the materials into paste by using a crusher, a grinder and a stirrer, heating the paste to boil for 15 minutes, filtering impurities and particles by using a filter screen to obtain the extracting solution of the plants, and cooling the extracting solution for later use;
s2, taking 10-20 parts of allium macrostemon, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of radix ophiopogonis, 5-10 parts of almond, 3-5 parts of radix peucedani, 5-10 parts of rhizoma cyperi and 3-5 parts of dried orange peel, washing with distilled water, placing in the sun for drying or drying by adopting drying equipment, and crushing and grinding by utilizing a crusher and a grinder to obtain a powdery mixture of the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the radix peucedani, the rhizoma cyperi and the dried orange peel for later use;
s3, mixing the plant extract obtained in the step 1 and the powdery mixture of the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the radix peucedani, the rhizoma cyperi and the dried orange peel obtained in the step 2, and stirring uniformly.
Preferably, the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the peucedanum, the rhizoma cyperi and the dried orange peel are all finished products obtained by steaming and drying the above plants in the sun.
The beneficial effects are as follows:
the caries-preventing mouthwash containing perilla leaves can play an antibacterial role through the perilla leaf extract contained in the caries-preventing mouthwash, can be used for treating cold by being matched with almond and whiteflower hogfennel root, can play a role in detoxifying, calming and relieving cough, can be used for treating symptoms of qi stagnation of spleen and stomach, chest distress and vomiting by being matched with rhizoma anemarrhenae, has the functions of moistening lung and clearing heart, purging heat and promoting fluid production by being matched with radix ophiopogonis, has the functions of activating yang and resolving masses and promoting qi circulation and removing stagnation of longstamen onion, and can further reduce the symptoms of the retching of a user by being matched with the effects of the perilla leaf extract, the rhizoma cyperi and the dried orange peel.
Detailed Description
All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows: an anticariogenic mouthwash containing perilla leaves comprises the following raw materials in parts by weight: 20 parts of perilla leaf, 15 parts of mint leaf, 15 parts of honeysuckle, 10 parts of allium macrostemon, 10 parts of rhizoma anemarrhenae, 10 parts of dwarf lilyturf tuber, 5 parts of almond, 5 parts of peucedanum root, 5 parts of nutgrass galingale rhizome, 5 parts of dried orange peel, and the finished products of the allium macrostemon, the rhizoma anemarrhenae, the dwarf lilyturf tuber, the almond, the peucedanum root, the nutgrass galingale rhizome and the dried orange peel which are all cooked and dried by adopting the plants, firstly, taking 20 parts of perilla leaf, 15 parts of mint leaf and 15 parts of honeysuckle, adding 100 parts of distilled water for soaking for 1.5 hours, respectively smashing, grinding and stirring by a grinder and a stirrer to be pasty, heating to boiling for 15 minutes, filtering impurities and particles by utilizing a filter screen to obtain the extract of the plants, cooling for later use, then, taking 10 parts of allium macrostemon, 10 parts of rhizoma anemarrhenae, 10 parts of dwarf lilyturf tuber, 5 parts of almond, 5 parts, pulverizing and grinding with a pulverizer and a grinder to obtain a powdery mixture of Bulbus Allii Macrostemi, rhizoma anemarrhenae, radix Ophiopogonis, semen Armeniacae amarum, radix Peucedani, rhizoma Cyperi and pericarpium Citri Tangerinae, and mixing the obtained plant extractive solution and the powdery mixture of Bulbus Allii Macrostemi, rhizoma anemarrhenae, radix Ophiopogonis, semen Armeniacae amarum, radix Peucedani, rhizoma Cyperi and pericarpium Citri Tangerinae.
Example two: an anticariogenic mouthwash containing perilla leaves comprises the following raw materials in parts by weight: 30 parts of perilla leaf, 10 parts of mint leaf, 10 parts of honeysuckle, 10 parts of allium macrostemon, 10 parts of rhizoma anemarrhenae, 10 parts of dwarf lilyturf tuber, 7 parts of almond, 3 parts of peucedanum root, 7 parts of nutgrass galingale rhizome, 3 parts of dried orange peel, and finished products of the allium macrostemon, the rhizoma anemarrhenae, the dwarf lilyturf tuber, the almond, the peucedanum root, the nutgrass galingale rhizome and the dried orange peel which are all cooked and dried by adopting the plants, firstly, 30 parts of perilla leaf, 10 parts of mint leaf and 10 parts of honeysuckle are taken, 100 parts of distilled water is added for soaking for 1.5 hours, a grinder, a stirrer are respectively used for crushing, grinding and stirring to be pasty, then, the mixture is heated to boiling for 15 minutes, impurities and particles are filtered by a filter screen to obtain extract of the plants, the extract is cooled for standby, then, 10 parts of the allium macrostemon, 10 parts of rhizoma anemarrhenae, 10 parts of dwarf lilyturf, pulverizing and grinding with a pulverizer and a grinder to obtain a powdery mixture of Bulbus Allii Macrostemi, rhizoma anemarrhenae, radix Ophiopogonis, semen Armeniacae amarum, radix Peucedani, rhizoma Cyperi and pericarpium Citri Tangerinae, and mixing the obtained plant extractive solution and the powdery mixture of Bulbus Allii Macrostemi, rhizoma anemarrhenae, radix Ophiopogonis, semen Armeniacae amarum, radix Peucedani, rhizoma Cyperi and pericarpium Citri Tangerinae.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (3)

1. An anticariogenic mouthwash containing perilla leaves is characterized in that: the material comprises the following raw materials in parts by weight: 20-40 parts of perilla leaf, 10-25 parts of mint leaf, 10-20 parts of honeysuckle, 10-20 parts of allium macrostemon, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of radix ophiopogonis, 5-10 parts of almond, 3-5 parts of radix peucedani, 5-10 parts of rhizoma cyperi and 3-5 parts of dried orange peel.
2. An anticariogenic mouthwash containing perilla leaves is characterized in that: comprises the following preparation steps:
s1, taking 20-40 parts of perilla leaves, 10-25 parts of mint leaves and 10-20 parts of honeysuckle, adding 100 parts of distilled water and 150 parts of distilled water, soaking for 1.5 hours, respectively crushing, grinding and stirring the materials into paste by using a crusher, a grinder and a stirrer, heating the paste to boil for 15 minutes, filtering impurities and particles by using a filter screen to obtain the extracting solution of the plants, and cooling the extracting solution for later use;
s2, taking 10-20 parts of allium macrostemon, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of radix ophiopogonis, 5-10 parts of almond, 3-5 parts of radix peucedani, 5-10 parts of rhizoma cyperi and 3-5 parts of dried orange peel, washing with distilled water, placing in the sun for drying or drying by adopting drying equipment, and crushing and grinding by utilizing a crusher and a grinder to obtain a powdery mixture of the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the radix peucedani, the rhizoma cyperi and the dried orange peel for later use;
s3, mixing the plant extract obtained in the step 1 and the powdery mixture of the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the radix peucedani, the rhizoma cyperi and the dried orange peel obtained in the step 2, and stirring uniformly.
3. The anti-caries mouthwash containing perilla leaves according to claim 2, wherein: the allium macrostemon, the rhizoma anemarrhenae, the radix ophiopogonis, the almond, the peucedanum root, the rhizoma cyperi and the dried orange peel are all finished products obtained by steaming and drying the above plants.
CN201910969763.XA 2019-10-12 2019-10-12 A collutory containing folium Perillae for preventing dental caries Pending CN112641873A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320401A (en) * 2017-08-18 2017-11-07 武汉华士特工业生物技术开发有限公司 A kind of mouthwash of pre- anti-caries and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320401A (en) * 2017-08-18 2017-11-07 武汉华士特工业生物技术开发有限公司 A kind of mouthwash of pre- anti-caries and preparation method thereof

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Application publication date: 20210413