CN112107517A - Children's mouth wash containing cymene bacteriostatic agent and preparation method thereof - Google Patents
Children's mouth wash containing cymene bacteriostatic agent and preparation method thereof Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 49
- 239000000022 bacteriostatic agent Substances 0.000 title claims abstract description 36
- 239000002324 mouth wash Substances 0.000 title claims abstract description 27
- 229940051866 mouthwash Drugs 0.000 title claims abstract description 24
- 229930007927 cymene Natural products 0.000 title claims abstract description 16
- HFPZCAJZSCWRBC-UHFFFAOYSA-N p-cymene Chemical compound CC(C)C1=CC=C(C)C=C1 HFPZCAJZSCWRBC-UHFFFAOYSA-N 0.000 title claims abstract description 16
- 239000003814 drug Substances 0.000 claims abstract description 42
- 239000000284 extract Substances 0.000 claims abstract description 38
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- 206010061218 Inflammation Diseases 0.000 claims abstract description 28
- 230000004054 inflammatory process Effects 0.000 claims abstract description 23
- 238000005728 strengthening Methods 0.000 claims abstract description 23
- 239000000463 material Substances 0.000 claims abstract description 22
- 208000002925 dental caries Diseases 0.000 claims abstract description 20
- 230000003467 diminishing effect Effects 0.000 claims abstract description 20
- 244000269722 Thea sinensis Species 0.000 claims abstract description 16
- 235000009569 green tea Nutrition 0.000 claims abstract description 16
- 239000011780 sodium chloride Substances 0.000 claims abstract description 16
- 241001116389 Aloe Species 0.000 claims abstract description 13
- 241000241413 Propolis Species 0.000 claims abstract description 13
- 244000228451 Stevia rebaudiana Species 0.000 claims abstract description 13
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 13
- 239000008367 deionised water Substances 0.000 claims abstract description 13
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 13
- 229940069949 propolis Drugs 0.000 claims abstract description 13
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 10
- 235000002566 Capsicum Nutrition 0.000 claims abstract description 10
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 10
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 10
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 10
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 10
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 10
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 10
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 10
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 10
- 239000006002 Pepper Substances 0.000 claims abstract description 10
- 235000016761 Piper aduncum Nutrition 0.000 claims abstract description 10
- 235000017804 Piper guineense Nutrition 0.000 claims abstract description 10
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 10
- 240000006079 Schisandra chinensis Species 0.000 claims abstract description 10
- 235000008422 Schisandra chinensis Nutrition 0.000 claims abstract description 10
- 235000006092 Stevia rebaudiana Nutrition 0.000 claims abstract description 10
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 10
- 235000011477 liquorice Nutrition 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 6
- 238000001223 reverse osmosis Methods 0.000 claims abstract description 5
- 241000572565 Alpinia oxyphylla Species 0.000 claims abstract description 4
- 241000213006 Angelica dahurica Species 0.000 claims abstract description 4
- 244000185386 Thladiantha grosvenorii Species 0.000 claims abstract description 4
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 claims abstract description 4
- 244000203593 Piper nigrum Species 0.000 claims abstract 4
- 238000010025 steaming Methods 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 10
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 6
- 238000007710 freezing Methods 0.000 claims description 6
- 230000008014 freezing Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 241000628997 Flos Species 0.000 claims description 3
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 229960001948 caffeine Drugs 0.000 claims description 3
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 3
- 235000009508 confectionery Nutrition 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 3
- 238000009489 vacuum treatment Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 9
- 208000025157 Oral disease Diseases 0.000 abstract description 4
- 208000030194 mouth disease Diseases 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 abstract description 2
- 208000003265 stomatitis Diseases 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 description 7
- 241000722363 Piper Species 0.000 description 6
- 210000000214 mouth Anatomy 0.000 description 6
- FBNAWLJSQORPAX-UHFFFAOYSA-N 4-methyl-3-propan-2-ylphenol Chemical compound CC(C)C1=CC(O)=CC=C1C FBNAWLJSQORPAX-UHFFFAOYSA-N 0.000 description 4
- 210000004489 deciduous teeth Anatomy 0.000 description 4
- 210000003296 saliva Anatomy 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000012676 herbal extract Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 210000001847 jaw Anatomy 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 210000003133 primary dentition Anatomy 0.000 description 2
- 230000005207 primary tooth eruption Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 201000004328 Pulpitis Diseases 0.000 description 1
- 206010037464 Pulpitis dental Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000675 anti-caries Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 210000002455 dental arch Anatomy 0.000 description 1
- 210000003707 mixed dentition Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000004622 sleep time Effects 0.000 description 1
- 235000021058 soft food Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 235000021147 sweet food Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a children mouthwash containing cymene bacteriostatic agent and a preparation method thereof, wherein the children mouthwash is prepared from the following materials: the traditional Chinese medicine comprises a traditional Chinese medicine extract, water, a bacteriostatic agent and sodium chloride, wherein the traditional Chinese medicine extract comprises a decayed tooth preventing component, a fire clearing and inflammation diminishing component and a tooth strengthening component, the water is deionized water prepared by an RO reverse osmosis method, the bacteriostatic agent is o-cymene-5-alcohol, the total weight of the traditional Chinese medicine extract, the water, the bacteriostatic agent and the sodium chloride is 100 percent, and the traditional Chinese medicine extract, the water, the bacteriostatic agent and the sodium chloride comprise the following components in percentage by weight: the traditional Chinese medicine composition comprises 35% of a traditional Chinese medicine extract, 60% of water, 4% of a bacteriostatic agent and 1% of sodium chloride, wherein the caries prevention component in the traditional Chinese medicine extract comprises green tea, the fire clearing and inflammation diminishing component comprises honeysuckle, mint, stevia rebaudiana, momordica grosvenori, propolis, aloe and liquorice, and the tooth strengthening component comprises sharpleaf galangal fruit, schisandra chinensis, lotus leaf, pepper and angelica dahurica. The children's mouth wash containing cymene bacteriostatic agent has effects of clearing pathogenic fire, diminishing inflammation and strengthening teeth, has no side effect, and can effectively prevent and treat oral diseases such as children's dental caries and stomatitis.
Description
Technical Field
The invention belongs to the technical field of children's mouth wash, and particularly relates to children's mouth wash containing cymene bacteriostatic agents and a preparation method thereof.
Background
The primary teeth begin to sprout in 6-7 months after birth, and the development of the primary dentition is completed in 3-6 years old, namely the primary dentition stage is in 6-6 months old. The 6-12 year old is the stage of mixed dentition, wherein deciduous teeth are exfoliated and permanent teeth are erupted in sequence until all deciduous teeth are replaced. At this stage, both deciduous teeth and permanent teeth exist in the oral cavity, which is the main growth and development period of the jaw and dental arch of children and the key period for establishing the permanent tooth jaw. According to the third national oral health epidemiological survey report, the caries rate of 5-year-old children in China is 66.0%. Dental caries is a bacterial disease, can cause pulpitis and periapicalitis, and can even cause inflammation of alveolar bones and jawbone and the like. The main relevant factors of tooth susceptibility to caries are: the number of times a child eats a sweet food per day and the intensity of oral cleansing. Children frequently eat the food, and the food is mostly soft food, and the viscidity is strong, and the sugar content is high, constitutes fertile soil of bacterium, forms the bacterial plaque easily, and a large amount of bacterium intakes the sugar in the saliva, decomposes the sugar and produces acid, and the saliva acidity increases after eating, and the saliva is in the acid state for a long time for eating many times, and more easily suffers from the caries than once eating equivalent food. The children have long sleep time, the oral cavity is in a static state, the saliva secretion is less, the self-cleaning effect is poor, the bacterial reproduction is facilitated, and the probability of caries is increased.
Mouthwash is one of the ways to clean the health of the mouth, and is generally better able to control plaque on the basis of effective tooth brushing. The mouthwash can penetrate into various parts of the oral cavity, reduce bacteria and bacterial plaque causing halitosis, and improve the health of the gum. The mouthwash is convenient to use and plays an important role in preventing and treating decayed teeth of children.
The existing children mouth wash only has simple cleaning and antibacterial effects, cannot realize the effects of clearing fire, strengthening teeth, diminishing inflammation and the like, and cannot realize the multiple-effect effects of health care, cleaning and the like by auxiliary treatment when children have oral diseases.
Disclosure of Invention
The invention aims to provide a children's mouthwash containing cymene bacteriostatic agent and a preparation method thereof, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the children's mouth wash containing the cymene bacteriostatic agent is prepared from the following materials: traditional Chinese medicine extract, water, bacteriostatic agent and sodium chloride;
wherein, the traditional Chinese medicine extract comprises a decayed tooth preventing component, a fire clearing and inflammation diminishing component and a tooth strengthening component, water is deionized water prepared by an RO reverse osmosis method, a bacteriostatic agent is o-cymene-5-alcohol, the total weight of the traditional Chinese medicine extract, the water, the bacteriostatic agent and sodium chloride is 100 percent, and the weight percentage of each component is as follows: 35% of traditional Chinese medicine extract, 60% of water, 4% of bacteriostatic agent and 1% of sodium chloride;
the traditional Chinese medicine extract accounts for 35% of the total weight, the caries preventing component comprises green tea, the fire clearing and inflammation diminishing component comprises honeysuckle, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice, and the teeth strengthening component comprises fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae.
Preferably, the proportion relationship of the caries preventing component, the fire clearing and inflammation diminishing component and the tooth strengthening component in the traditional Chinese medicine extract is 3:1: 1.
Preferably, the components for clearing away the fire and diminishing inflammation comprise honeysuckle, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice in a weight percentage of 100 percent based on the total weight, wherein the weight percentages of the components are as follows: 30% of honeysuckle, 5% of mint, 30% of stevia rebaudiana, 15% of momordica grosvenori, 5% of propolis, 10% of aloe and 5% of liquorice.
Preferably, the teeth-strengthening components comprise fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae dahuricae, the weight percentages of the components are as follows based on 100% of the total weight: 30% of fructus alpiniae oxyphyllae, 30% of schisandra chinensis, 20% of lotus leaves, 10% of pepper and 10% of angelica dahurica.
A process for preparing a mouthwash for children's mouthwashes containing cymene bacteriostatic agents according to claim 1, comprising the steps of:
s1, preparing traditional Chinese medicine extracts;
s2, preparing deionized water;
s3, mixing the traditional Chinese medicine extract, deionized water, a bacteriostatic agent and sodium chloride;
and S4, vacuum filling.
Preferably, in S1, the preparation of the herbal extract further comprises preparation of a component for preventing dental caries, preparation of a component for clearing away fire and diminishing inflammation, and preparation of a component for strengthening teeth;
the preparation of the caries-preventing component comprises the following steps: crushing green tea, sieving with a 100-mesh sieve, putting into an extraction kettle, and removing caffeine by a supercritical fluid extraction instrument to obtain decaffeinated green tea;
the preparation of the component for clearing away fire and diminishing inflammation comprises the following steps: placing flos Lonicerae, herba Menthae, sweet stevia, fructus Siraitiae Grosvenorii, propolis, Aloe and Glycyrrhrizae radix into a freezing box at-7.5 deg.C, freezing for 30min, taking out, placing into a steaming box at 180 deg.C, steaming for 25min, and taking out to obtain first preparation material;
the preparation of the tooth fixing component comprises the following steps: parching fructus Alpinae Oxyphyllae, fructus Schisandrae chinensis, folium Nelumbinis, fructus Zanthoxyli and radix Angelicae Dahuricae in 80 deg.C pan for 25min, taking out, steaming in 220 deg.C steam oven for 30min, and taking out to obtain the second preparation material.
Preferably, the preparation of the traditional Chinese medicine extract further comprises the steps of steaming and mixing the decaffeinated green tea, the first preparation material and the second preparation material, uniformly mixing the decaffeinated green tea, the first preparation material and the second preparation material with absolute ethyl alcohol, carrying out vacuum treatment for 25min, taking out, putting into deionized water, boiling with strong fire, continuing to boil with slow fire for 60min, taking out, cooling and filtering.
The invention has the technical effects and advantages that: the children mouth wash containing the cymene bacteriostatic agent and the preparation method thereof adopt the traditional Chinese medicine components, combine the o-cymene-5-ol, and the o-cymene-5-ol has stable chemical properties, and has obvious effects of inhibiting and killing bacteria and fungi, and the breeding of oral bacteria is reduced after the addition; the traditional Chinese medicine extract is prepared by mixing the decayed tooth preventing component, the inflammation-diminishing component and the tooth strengthening component, so that further decayed tooth prevention of the oral cavity is realized, the traditional Chinese medicine extract has auxiliary effects of clearing heat, diminishing inflammation and strengthening teeth, has no side effect, and effectively prevents and treats oral diseases such as decayed tooth and stomatitis of children.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a children's mouthwash containing cymene bacteriostatic agent, which is prepared from the following materials: traditional Chinese medicine extract, water, bacteriostatic agent and sodium chloride;
wherein, the traditional Chinese medicine extract comprises a decayed tooth preventing component, a fire clearing and inflammation diminishing component and a tooth strengthening component, water is deionized water prepared by an RO reverse osmosis method, a bacteriostatic agent is o-cymene-5-alcohol, the total weight of the traditional Chinese medicine extract, the water, the bacteriostatic agent and sodium chloride is 100 percent, and the weight percentage of each component is as follows: the traditional Chinese medicine composition comprises 35% of traditional Chinese medicine extract, 60% of water, 4% of bacteriostatic agent and 1% of sodium chloride, adopts traditional Chinese medicine components, combines o-cymene-5-ol, has stable chemical properties of the o-cymene-5-ol, has obvious effects of inhibiting and killing bacteria and fungi, and reduces the breeding of oral bacteria after being added;
the traditional Chinese medicine extract is characterized in that the anti-caries component comprises green tea, the inflammation-relieving component comprises honeysuckle, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice, the tooth-strengthening component comprises fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae, the dental caries prevention component, the inflammation-relieving component and the tooth-strengthening component in the traditional Chinese medicine extract are mixed to further prevent dental caries in the oral cavity, and the traditional Chinese medicine extract has auxiliary effects of relieving inflammation and strengthening teeth, has no side effect, and effectively prevents and treats oral diseases such as children dental caries, oral inflammation and the like.
Specifically, the proportion relationship of the caries preventing component, the fire clearing and inflammation diminishing component and the tooth strengthening component in the traditional Chinese medicine extract is 3:1: 1.
Specifically, the components of honeysuckle flower, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice in the internal heat-clearing and inflammation-diminishing component account for 100 percent of the total weight, and the weight content percentages of the components are as follows: 30% of honeysuckle, 5% of mint, 30% of stevia rebaudiana, 15% of momordica grosvenori, 5% of propolis, 10% of aloe and 5% of liquorice.
Specifically, the teeth-strengthening components comprise fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae dahuricae, wherein the total weight is 100%, and the weight percentage of each component is as follows: 30% of fructus alpiniae oxyphyllae, 30% of schisandra chinensis, 20% of lotus leaves, 10% of pepper and 10% of angelica dahurica.
A process for preparing a mouthwash for children's mouthwashes containing cymene bacteriostatic agents according to claim 1, comprising the steps of:
s1, preparing traditional Chinese medicine extracts;
s2, preparing deionized water by an RO reverse osmosis method;
s3, mixing the traditional Chinese medicine extract, deionized water, a bacteriostatic agent and sodium chloride;
and S4, vacuum filling.
Specifically, in S1, the preparation of the herbal extract further comprises the preparation of a component for preventing dental caries, the preparation of a component for clearing away fire and diminishing inflammation, and the preparation of a component for strengthening teeth;
the preparation of the caries-preventing component comprises the following steps: crushing green tea, sieving with a 100-mesh sieve, putting into an extraction kettle, and removing caffeine by a supercritical fluid extraction instrument to obtain decaffeinated green tea;
the preparation of the component for clearing away fire and diminishing inflammation comprises the following steps: placing flos Lonicerae, herba Menthae, sweet stevia, fructus Siraitiae Grosvenorii, propolis, Aloe and Glycyrrhrizae radix into a freezing box at-7.5 deg.C, freezing for 30min, taking out, placing into a steaming box at 180 deg.C, steaming for 25min, and taking out to obtain first preparation material;
the preparation of the tooth fixing component comprises the following steps: parching fructus Alpinae Oxyphyllae, fructus Schisandrae chinensis, folium Nelumbinis, fructus Zanthoxyli and radix Angelicae Dahuricae in 80 deg.C pan for 25min, taking out, steaming in 220 deg.C steam oven for 30min, and taking out to obtain the second preparation material.
Specifically, the preparation of the traditional Chinese medicine extract further comprises the steps of steaming and mixing the decaffeinated green tea, the first preparation material and the second preparation material, uniformly mixing the decaffeinated green tea, the first preparation material and the second preparation material with absolute ethyl alcohol, carrying out vacuum treatment for 25min, taking out, putting into deionized water, boiling with strong fire, continuing to boil with slow fire for 60min, taking out, cooling and filtering.
Therapeutic Effect (Classification according to the same type of symptoms in the following Table)
Table 1:
table 2:
finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (7)
1. The children's mouth wash containing the cymene bacteriostatic agent is characterized by being prepared from the following materials: traditional Chinese medicine extract, water, bacteriostatic agent and sodium chloride;
wherein, the traditional Chinese medicine extract comprises a decayed tooth preventing component, a fire clearing and inflammation diminishing component and a tooth strengthening component, water is deionized water prepared by an RO reverse osmosis method, a bacteriostatic agent is o-cymene-5-alcohol, the total weight of the traditional Chinese medicine extract, the water, the bacteriostatic agent and sodium chloride is 100 percent, and the weight percentage of each component is as follows: 35% of traditional Chinese medicine extract, 60% of water, 4% of bacteriostatic agent and 1% of sodium chloride;
the traditional Chinese medicine extract accounts for 35% of the total weight, the caries preventing component comprises green tea, the fire clearing and inflammation diminishing component comprises honeysuckle, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice, and the teeth strengthening component comprises fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae.
2. The children's mouthwash containing cymene bacteriostatic agents according to claim 1, wherein: the proportion relationship of the caries-preventing component, the fire-clearing inflammation-diminishing component and the tooth-strengthening component in the traditional Chinese medicine extract is 3:1: 1.
3. The children's mouthwash containing cymene bacteriostatic agents according to claim 2, wherein: the components of honeysuckle flower, mint, stevia rebaudiana, fructus momordicae, propolis, aloe and liquorice for clearing fire and diminishing inflammation account for 100 percent of the total weight, and the weight content percentages of the components are as follows: 30% of honeysuckle, 5% of mint, 30% of stevia rebaudiana, 15% of momordica grosvenori, 5% of propolis, 10% of aloe and 5% of liquorice.
4. The children's mouthwash containing cymene bacteriostatic agents according to claim 2, wherein: the tooth-strengthening components comprise fructus alpiniae oxyphyllae, schisandra chinensis, lotus leaves, pepper and radix angelicae, wherein the total weight is 100%, and the weight percentages of the components are as follows: 30% of fructus alpiniae oxyphyllae, 30% of schisandra chinensis, 20% of lotus leaves, 10% of pepper and 10% of angelica dahurica.
5. A process for preparing a mouthwash for children's mouthwashes containing cymene bacteriostatic agents according to claim 1, characterized in that it comprises the following steps:
s1, preparing traditional Chinese medicine extracts;
s2, preparing deionized water;
s3, mixing the traditional Chinese medicine extract, deionized water, a bacteriostatic agent and sodium chloride;
and S4, vacuum filling.
6. A process for the preparation of a mouthwash according to claim 5, characterized in that: in the S1, the preparation of the Chinese medicinal extract also comprises the preparation of a decayed tooth preventing component, the preparation of a fire clearing and inflammation diminishing component and the preparation of a tooth strengthening component;
the preparation of the caries-preventing component comprises the following steps: crushing green tea, sieving with a 100-mesh sieve, putting into an extraction kettle, and removing caffeine by a supercritical fluid extraction instrument to obtain decaffeinated green tea;
the preparation of the component for clearing away fire and diminishing inflammation comprises the following steps: placing flos Lonicerae, herba Menthae, sweet stevia, fructus Siraitiae Grosvenorii, propolis, Aloe and Glycyrrhrizae radix into a freezing box at-7.5 deg.C, freezing for 30min, taking out, placing into a steaming box at 180 deg.C, steaming for 25min, and taking out to obtain first preparation material;
the preparation of the tooth fixing component comprises the following steps: parching fructus Alpinae Oxyphyllae, fructus Schisandrae chinensis, folium Nelumbinis, fructus Zanthoxyli and radix Angelicae Dahuricae in 80 deg.C pan for 25min, taking out, steaming in 220 deg.C steam oven for 30min, and taking out to obtain the second preparation material.
7. A process for preparing a mouthwash according to claim 6, characterized in that: the preparation method of the traditional Chinese medicine extract also comprises the steps of steaming and mixing the decaffeinated green tea, the first preparation material and the second preparation material, uniformly mixing the decaffeinated green tea, the first preparation material and the second preparation material with absolute ethyl alcohol, carrying out vacuum treatment for 25min, taking out, putting into deionized water, boiling with strong fire, continuing to boil with slow fire for 60min, taking out, cooling and filtering.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209603A (en) * | 2021-12-17 | 2022-03-22 | 上海美加净日化有限公司 | Mouthwash and preparation method thereof |
| CN114392227A (en) * | 2022-03-02 | 2022-04-26 | 厦门市益坊生物科技有限公司 | Gargle tea with functions of diminishing inflammation and removing halitosis and preparation process thereof |
-
2020
- 2020-10-08 CN CN202011068165.4A patent/CN112107517A/en active Pending
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| 周德胜 等: "《实用临床中西药合用解读》", 31 December 2016 * |
| 国家药典委员会: "《中华人民共和国药典》", 27 June 2008 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209603A (en) * | 2021-12-17 | 2022-03-22 | 上海美加净日化有限公司 | Mouthwash and preparation method thereof |
| CN114209603B (en) * | 2021-12-17 | 2023-11-21 | 上海美加净日化有限公司 | Mouthwash and preparation method thereof |
| CN114392227A (en) * | 2022-03-02 | 2022-04-26 | 厦门市益坊生物科技有限公司 | Gargle tea with functions of diminishing inflammation and removing halitosis and preparation process thereof |
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Application publication date: 20201222 |