CN105997792A - Traditional Chinese medicine mothproofing and tooth-protecting gargle and preparation method thereof - Google Patents
Traditional Chinese medicine mothproofing and tooth-protecting gargle and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/16—Fluorine compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
The invention discloses traditional Chinese medicine mothproofing and tooth-protecting gargle. The gargle is prepared from a green tea extract, a fructus momordicae extract, a 20 wt% ethanol water extract of rhizoma corydalis, a cortex lycii radicis extract, a gallnut extract, sodium fluoride, gluconic acid chlorhexidine, potassium nitrate, thymol, coconut oil fatty acid monoethanol amide, a sweetening agent and deionized water. The oral cavity gargle which takes natural Chinese herbal medicines as the main ingredients can overcome the above-mentioned defects, has multiple effects of clearing heat, removing toxicity, diminishing inflammation, achieving sterilization, cleaning the oral cavity, removing odors and preventing decayed teeth on currently common oral diseases such as gingival bleeding, gingival pain and swelling and stomatitis, has a certain effect on preventing throat infections and oral cancers and is free of toxic and side effects on human bodies.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of gargarism and preparation method thereof, particularly relate to one
Chinese medicine mothproof tooth protection gargarism and preparation method thereof.
Background technology
Since half a century, the mankind in order to clean oral cavity, take care of one's teeth employ dentifrice to toothpaste two generation produce
Product.But up to now, the disease such as gingival hemorrhage, abscess, dental caries, stomatitis still annoyings the mankind,
It is classified as the world four big oral cavity difficulty disease by World Health Organization (WHO).
In China, oral disease sickness rate is higher, and cleans oral cavity and effectively press down the Oral Pathogens that goes out, and is
The most efficient method of prevention oral disease.At present, China is for liquid oral health product, also in opening
Sending out the stage developing batch production, in the various gargarism of external exploitation and marketing, the overwhelming majority is fluorination
Thing and hibitane product, can cause chronic fluorosis and the disadvantage of tooth Huang after people's life-time service.
Summary of the invention
For above-mentioned weak point, it is an object of the invention to provide a kind of with natural Chinese medicinal herb for main one-tenth
Part oral cavity gargle, it can overcome above-mentioned deficiency, to the most common gingival hemorrhage, gingival swelling and pain,
The oral diseases such as stomatitis have heat-clearing and toxic substances removing, antiphlogistic and bactericidal, cleaning oral cavity, eliminate abnormal flavour, pre-preventing decayed tooth
Tooth multiple efficacies, also has certain effect to prevention bottleneck throat infection, mouth cancers, and to human non-toxic
Side effect.
Technical scheme is summarized as follows: a kind of Chinese medicine mothproof tooth protection gargarism, including following weight
The composition of part: green tea extract 4～10 parts；Fructus Momordicae extract 1～3 parts；Rhizoma Corydalis 20wt% ethanol water
Extract 1～10 parts；Cortex Lycii extract 2～8 parts；Galla Chinensis extract 1～8 parts；Sodium fluoride 0.5～
3 parts；Chlorhexidine gluconate 3～7 parts；Potassium nitrate 1～4 parts；Thymol 1～3 parts；Coconut oil
Single ethanol amide 0.5～3 parts；Sweeting agent 1～3 parts；Deionized water 100～180 parts.
Preferably, including the composition of following weight portion: green tea extract 5～7 parts；Fructus Momordicae extract
1～2 part；Rhizoma Corydalis 20wt% ethanol-water extraction thing 3～8 parts；Cortex Lycii extract 4～7 parts；Galla Chinensis
Extract 2～5 parts；Sodium fluoride 1～2 parts；Chlorhexidine gluconate 4～6 parts；Potassium nitrate 1.5～3 parts；
Thymol 1～2.5 parts；Coconut Fatty Acid Monoethanolamide 1～2.5 parts；Sweeting agent 1～3 parts；Deionization
Water 120～160 parts.
Preferably, including the composition of following weight portion: green tea extract 6 parts；Fructus Momordicae extract 1.5
Part；Rhizoma Corydalis 20wt% ethanol-water extraction thing 4 parts；Cortex Lycii extract 6 parts；Galla Chinensis extract 4 parts；
Sodium fluoride 1.5 parts；Chlorhexidine gluconate 5 parts；Potassium nitrate 2 parts；Thymol 2 parts；Coconut oil
Single ethanol amide 2 parts；Sweeting agent 2 parts；Deionized water 120～160 parts.
Preferably, the one during described sweeting agent is selected from xylitol, stevioside, aspartame or its group
Close.
It is a further object to provide a kind of medicine mothproof tooth protection gargarism preparation method, including as follows
Step:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 1～4 hour, then be stirred hot dipping and carry, hot dipping is centrifugal after carrying, and collects supernatant, respectively by upper
Clear liquid concentrates, and respectively obtains green tea extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis carry
Take thing；
Step 2): take Rhizoma Corydalis and smash to pieces, extract, after extraction with the ethanol water of 20wt% after smashing to pieces
Centrifugation, by filter vacuum thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Preferably, hot-water soak 2h in described step (1), extraction temperature is 50～60 DEG C, extraction
Time is 3～5h, and feed liquid weight ratio is 1:5～1:10.
Preferably, in described step (2), Extracting temperature is 40～70 DEG C, and extraction time is 2～5h, material
Liquid weight ratio is 1:4～1:10.
The invention has the beneficial effects as follows: this case provides a kind of oral cavity with natural Chinese medicinal herb as Main Ingredients and Appearance to contain
Gargarism, it can overcome above-mentioned deficiency, to mouths such as the most common gingival hemorrhage, gingival swelling and pain, stomatitis
Chamber illness has heat-clearing and toxic substances removing, antiphlogistic and bactericidal, a cleaning oral cavity, eliminates abnormal flavour, pre-anti-caries multiple efficacies,
Infect prevention bottleneck throat, mouth cancers also has certain effect, and to human non-toxic's side effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art join
Book word can be implemented according to this as directed.
Embodiment 1
A kind of Chinese medicine mothproof tooth protection gargarism, including the composition of following weight portion: green tea extract 4 parts；
Fructus Momordicae extract 1 part；Rhizoma Corydalis 20wt% ethanol-water extraction thing 1 part；Cortex Lycii extract 2 parts；Five
Times seed extract 1 part；Sodium fluoride 0.5 part；Chlorhexidine gluconate 3 parts；Potassium nitrate 1 part；Moschus
Grass phenol 1 part；Coconut Fatty Acid Monoethanolamide 0.5 part；Aspartame 1 part；Deionized water 100 parts.
Its preparation method containing following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 1 hour, then be stirred hot dipping and carry, extraction temperature is 50 DEG C, and extraction time is 3h, feed liquid weight
Amount ratio is 1:5, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains green tea
Extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis extract；
Step 2): take Rhizoma Corydalis and smash to pieces, extract with the ethanol water of 20wt% after smashing to pieces, extract temperature
Degree is 40 DEG C, and extraction time is 2h, and feed liquid weight ratio is 1:4, and centrifugation after extraction is true by filtrate
Empty thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Embodiment 2
A kind of Chinese medicine mothproof tooth protection gargarism, including the composition of following weight portion: green tea extract 10 parts；
Fructus Momordicae extract 3 parts；Rhizoma Corydalis 20wt% ethanol-water extraction thing 10 parts；Cortex Lycii extract 8 parts；Five
Times seed extract 8 parts；Sodium fluoride 3 parts；Chlorhexidine gluconate 7 parts；Potassium nitrate 4 parts；Herba thymi vulgaris
3 parts of phenol；Coconut Fatty Acid Monoethanolamide 3 parts；Aspartame 3 parts；Deionized water 180 parts.
Its preparation method containing following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 4 hours, then be stirred hot dipping and carry, extraction temperature is 60 DEG C, and extraction time is 5h, feed liquid weight
Amount ratio is 1:10, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains green
Tea extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis extract；
Step 2): take Rhizoma Corydalis and smash to pieces, extract with the ethanol water of 20wt% after smashing to pieces, extract temperature
Degree is 70 DEG C, and extraction time is 5h, and feed liquid weight ratio is 1:10, and centrifugation after extraction is true by filtrate
Empty thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Embodiment 3
A kind of Chinese medicine mothproof tooth protection gargarism, including the composition of following weight portion: green tea extract 5 parts；
Fructus Momordicae extract 1 part；Rhizoma Corydalis 20wt% ethanol-water extraction thing 3 parts；Cortex Lycii extract 4 parts；Five
Times seed extract 2 parts；Sodium fluoride 1 part；Chlorhexidine gluconate 4 parts；Potassium nitrate 1.5 parts；Moschus
Grass phenol 1 part；Coconut Fatty Acid Monoethanolamide 1 part；Xylitol 1 part；Deionized water 120 parts.
Its preparation method containing following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 4 hours, then be stirred hot dipping and carry, extraction temperature is 60 DEG C, and extraction time is 5h, feed liquid weight
Amount ratio is 1:10, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains green
Tea extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis extract；
Step 2): take Rhizoma Corydalis and smash to pieces, extract with the ethanol water of 20wt% after smashing to pieces, extract temperature
Degree is 40 DEG C, and extraction time is 2h, and feed liquid weight ratio is 1:4, and centrifugation after extraction is true by filtrate
Empty thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Embodiment 4
A kind of Chinese medicine mothproof tooth protection gargarism, including the composition of following weight portion: green tea extract 7 parts；
Fructus Momordicae extract 2 parts；Rhizoma Corydalis 20wt% ethanol-water extraction thing 8 parts；Cortex Lycii extract 7 parts；Five
Times seed extract 5 parts；Sodium fluoride 2 parts；Chlorhexidine gluconate 6 parts；Potassium nitrate 3 parts；Herba thymi vulgaris
2.5 parts of phenol；Coconut Fatty Acid Monoethanolamide 2.5 parts；Xylitol 3 parts；Deionized water 160 parts.
Its preparation method containing following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 3 hours, then be stirred hot dipping and carry, extraction temperature is 55 DEG C, and extraction time is 4h, feed liquid weight
Amount ratio is 1:7, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains green tea
Extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis extract；
Step 2): take Rhizoma Corydalis and smash to pieces, extract with the ethanol water of 20wt% after smashing to pieces, extract temperature
Degree is 50 DEG C, and extraction time is 3h, and feed liquid weight ratio is 1:8, and centrifugation after extraction is true by filtrate
Empty thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Embodiment 5
A kind of Chinese medicine mothproof tooth protection gargarism, including the composition of following weight portion: green tea extract 6 parts；
Fructus Momordicae extract 1.5 parts；Rhizoma Corydalis 20wt% ethanol-water extraction thing 4 parts；Cortex Lycii extract 6 parts；
Galla Chinensis extract 4 parts；Sodium fluoride 1.5 parts；Chlorhexidine gluconate 5 parts；Potassium nitrate 2 parts；Moschus moschiferous
2 parts of Rhizoma et radix valerianae phenol；Coconut Fatty Acid Monoethanolamide 2 parts；Stevioside 2 parts；Deionized water 120～160 parts.
Its preparation method containing following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 2 hours, then be stirred hot dipping and carry, extraction temperature is 55 DEG C, and extraction time is 4.5h, feed liquid
Weight ratio is 1:8, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains green
Tea extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis extract；
Step 2): take Rhizoma Corydalis and smash to pieces, extract with the ethanol water of 20wt% after smashing to pieces, extract temperature
Degree is 60 DEG C, and extraction time is 4h, and feed liquid weight ratio is 1:8, and centrifugation after extraction is true by filtrate
Empty thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
Although embodiment of the present invention are disclosed as above, but it is not restricted to description and embodiment party
Listed utilization in formula, it can be applied to various applicable the field of the invention completely, for being familiar with ability
For the personnel in territory, be easily achieved other amendment, therefore without departing substantially from claim and etc. homotype
Enclosing under limited general concept, the present invention is not limited to specific details.
Claims (7)
1. a Chinese medicine mothproof tooth protection gargarism, it is characterised in that include the composition of following weight portion: green
Tea extract 4～10 parts；Fructus Momordicae extract 1～3 parts；Rhizoma Corydalis 20wt% ethanol-water extraction thing 1～10
Part；Cortex Lycii extract 2～8 parts；Galla Chinensis extract 1～8 parts；Sodium fluoride 0.5～3 parts；Fructus Vitis viniferae
Saccharic acid chlorhexidine 3～7 parts；Potassium nitrate 1～4 parts；Thymol 1～3 parts；Coconut Fatty Acid Monoethanolamide
0.5～3 part；Sweeting agent 1～3 parts；Deionized water 100～180 parts.
2. Chinese medicine mothproof tooth protection gargarism as claimed in claim 1, it is characterised in that include following heavy
The composition of amount part: green tea extract 5～7 parts；Fructus Momordicae extract 1～2 parts；Rhizoma Corydalis 20wt% ethanol water
Extract 3～8 parts；Cortex Lycii extract 4～7 parts；Galla Chinensis extract 2～5 parts；Sodium fluoride 1～2
Part；Chlorhexidine gluconate 4～6 parts；Potassium nitrate 1.5～3 parts；Thymol 1～2.5 parts；Cocos nucifera oil
Acid single ethanol amide 1～2.5 parts；Sweeting agent 1～3 parts；Deionized water 120～160 parts.
Chinese medicine the most as claimed in claim 1 mothproof tooth protection gargarism, it is characterised in that include following
The composition of weight portion: green tea extract 6 parts；Fructus Momordicae extract 1.5 parts；Rhizoma Corydalis 20wt% ethanol water
Extract 4 parts；Cortex Lycii extract 6 parts；Galla Chinensis extract 4 parts；Sodium fluoride 1.5 parts；Fructus Vitis viniferae
Saccharic acid chlorhexidine 5 parts；Potassium nitrate 2 parts；Thymol 2 parts；Coconut Fatty Acid Monoethanolamide 2 parts；Sweet
Taste agent 2 parts；Deionized water 120～160 parts.
4. the Chinese medicine mothproof tooth protection gargarism as described in claims 1 to 3, it is characterised in that described sweet
Taste agent is selected from the one in xylitol, stevioside, aspartame or a combination thereof.
5. Chinese medicine mothproof tooth protection gargarism preparation method as claimed in claim 1, it is characterised in that bag
Include following steps:
Step 1): take green tea, Fructus Momordicae, Cortex Lycii, Galla Chinensis are smashed to pieces, are separately added into hot water after smashing to pieces
Soaking 1～4 hour, then be stirred hot dipping and carry, hot dipping is centrifugal after carrying, and collects supernatant, respectively by upper
Clear liquid concentrates, and respectively obtains green tea extract, Fructus Momordicae extract, Cortex Lycii extract, Galla Chinensis carry
Take thing；
Step 2): take Rhizoma Corydalis and smash to pieces, extract, after extraction with the ethanol water of 20wt% after smashing to pieces
Centrifugation, by filter vacuum thin film evaporation, obtains Rhizoma Corydalis 20wt% ethanol-water extraction thing；
Step 3): take by weight green tea extract, Fructus Momordicae extract, Cortex Lycii extract, five times
Seed extract, Rhizoma Corydalis 20wt% ethanol-water extraction thing, sodium fluoride, chlorhexidine gluconate, potassium nitrate,
Thymol, Coconut Fatty Acid Monoethanolamide, sweeting agent and deionized water, by above-mentioned various extracts
And other adjuvant mix homogeneously, obtain Chinese medicine mothproof tooth protection gargarism.
6. Chinese medicine mothproof tooth protection gargarism preparation method as claimed in claim 5, it is characterised in that institute
Stating hot-water soak 2h in step (1), extraction temperature is 50～60 DEG C, and extraction time is 3～5h, feed liquid
Weight ratio is 1:5～1:10.
7. Chinese medicine mothproof tooth protection gargarism preparation method as claimed in claim 5, it is characterised in that institute
Stating Extracting temperature in step (2) is 40～70 DEG C, and extraction time is 2～5h, and feed liquid weight ratio is 1:4～1:10.
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