CN103735481A - Antisepsis and anti-inflammation mouth rinse and preparation method thereof - Google Patents
Antisepsis and anti-inflammation mouth rinse and preparation method thereof Download PDFInfo
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Abstract
The invention relates to antisepsis and anti-inflammation mouth rinse and a preparation method thereof, and belongs to dental nursing products. The antisepsis and anti-inflammation mouth rinse is characterized by comprising the following components in parts by weight: 50-60 parts of honeybee comb, 6-10 parts of natural mature honey, 1-2 parts of mint, 6-8 parts of siraitia grosvenorii, 2-8 parts of sorbitol, 0.05-0.2 part of a sweetening agent, 70-80 parts of deionized water, and 0.1-0.2 part of preservative. Due to the natural raw materials serving as active components, and the mouth rinse has the effects of clearing and smoothing laryngopharynx, eliminating bed breath, diminishing inflammation and sterilizing, preventing and treating decayed teeth and the like, and has a good auxiliary treatment effect to rhinitis, sphagitis, cough, toothache and the like. The mouth rinse can be used for preventing and treating decayed teeth by adopting honeycomb concentrate, and avoiding injury of fluorine poisoning and the like to human bodies by using fluorine containing compounds as a decaying inhibitor. The preparation method is simple, and easy to popularize and apply.
Description
Technical field
The invention belongs to daily necessities field, be specifically related to a kind of anti-inflammation collutory and preparation method thereof.
Background technology
Along with the raising of expanding economy and people's living standard, oral hygiene is more and more subject to people's attention.It is believed that brushes teeth sooner or later in the past just can reach sanitary standard, can but be nowhere near with regard to oral hygiene new concept.Expert proposes: cleaning oral cavity is essential as washing one's hands.But but take whenever and wherever possible, collutory goes out toothpaste, toothbrush is unrealistic, and at this moment collutory just can stand up and volunteer to help, and takes on heavy burden, and anytime anywhere it can be people's cleaning oral cavity, the erosion of refusal residue to tooth; Moreover, in some occasions, have meal, contain the highly seasoned cuisines such as Herba Alii fistulosi, Bulbus Allii, you " are tried to stop but cannot ", but do not have no idea, a standby small vial of mouthwash, only need go to time toilet, ability to speak is pure and fresh at once, without vestige, you can be glutted oneself with delicacies to the greatest extent; Secondly, in travelling way, water tank lacks water or water are crowded all often to be had, standby bottle collutory, and all worries one have been gargled it; In addition, collutory also will be the old man of loss of tooth, the child that can not brush teeth and the optimum selection of being impatient at odontopathy patient's oral hygiene guarantee of brushing teeth.
At present, collutory is divided into clean type and the large class of therapeutic type two by effect.The Main Function of clean type collutory is to remove halitosis, and therapeutic type is mainly the commonly encountered diseases in oral cavity to be carried out to auxiliary treatment.Collutory effect on market is more single now, is difficult to the demand of compound people to collutory.
For oral problem, generally adopt two kinds of methods: 1) pharmaceutical preparation, to add broad-spectrum antibiotic and chemicals as main, life-time service can destroy oral microorganism balance; 2) biologically active agents.In recent years, many research worker join biologically active agents in oral care product, have obtained good effect.Chinese patent CN200310101961.3, concentrated mouthwash agent composition of a kind of propolis and preparation method thereof, the main active of this patent using propolis as collutory, be mainly used in antibacterial, antiinflammatory, treatment oral ulcer, but still its main active only has propolis, act on limitedly, cannot meet the requirement of people to multifunctional gargle.Chinese patent CN200910088890.5, a kind of collutory and preparation method thereof, in this patent, active component is on the basis of propolis, Cortex Magnoliae Officinalis, tea polyphenols have been added, there is multi-efficiency, but due to the poorly water-soluble of its active component, need to add appropriate ethanol, this not only makes manyly to the people of ethanol allergy, cannot use this product, also can containing the people's of spirituous collutory health, cause damage to long-term taking.
In addition, many research worker are added many fluorine-containing materials for anti-caries, as adopted ammonium hexafluorosilicate in Chinese patent CN201010549095.4, be caries preventive agent, it is caries preventive agent that Chinese patent CN201010173234.8 adopts sodium fluoride, potassium fluoride, sodium monofluorophosphate.In oral care implement, a large amount of use fluorochemicals are that corrosivity is very strong because fluorine chemistry character is very active as caries preventive agent, both noxious bacteria are had and are suppressed and lethal effect, also can bring impact to human body.Therefore, fluorine is listed in " human body may be essential, but have the trace element of genotoxic potential " by international bodies such as World Health Organization (WHO)s, and lead, cadmium, hydrargyrum, arsenic, aluminum, lithium, stannum etc. come a class.In human body, fluorinated volume is too high, on tooth, skeleton, affect very large, excessively use fluorine-containing article can cause fluorosis, also may damage nervous system, cause osteoporosis, even cause heart disease etc., especially 7 years old following child, expert does not advise that they use fluorine-containing article, reduces the probability of fluorosis.
How to overcome the deficiencies in the prior art, produce and a kind ofly there is multi-efficiency and nonalcoholic floride-free collutory is the problem that current daily necessities field is needed solution badly.
Summary of the invention
The object of the invention is, in order to solve the deficiencies in the prior art, provides a kind of anti-inflammation collutory and preparation method thereof, the multiple efficacies such as that collutory of the present invention has is antibacterial, antiinflammatory, cough-relieving.
The technological invention that the present invention adopts is as follows:
A kind of anti-inflammation collutory, is characterized in that comprising the following component according to parts by weight meter: 50 ~ 60 parts of honey combs, 6 ~ 10 parts of natural ripe Mel, 1 ~ 2 part of Herba Menthae, 6 ~ 8 parts of Fructus Momordicaes, 2 ~ 8 parts of sorbitol, 0.05 ~ 0.2 part of sweeting agent, 70 ~ 80 parts of deionized waters, 0.1 ~ 0.2 part of antiseptic.
The further preferred version of the present invention is that described sweeting agent is one or more in Aspartame, acesulfame potassium, stevioside, xylitol.
Further, it is preferably invented and selects the honey comb not going mouldy above for 3 years for described honey comb.
Further, it is preferably invented as anti-inflammation collutory of the present invention, it is characterized in that the component that contains following parts by weight: 50 parts of honey combs, 7 parts of natural ripe Mel, 1.5 parts of Herba Menthaes, 8 parts of Fructus Momordicaes, 4 parts of sorbitol, 0.1 part of Aspartame, 70 parts of deionized waters, 0.12 part of antiseptic.
Further, it is preferably invented as anti-inflammation collutory of the present invention, it is characterized in that the component that contains following parts by weight: 54 parts of honey combs, 8 parts of natural ripe Mel, 2 parts of Herba Menthaes, 6.8 parts of Fructus Momordicaes, 5.5 parts of sorbitol, 0.05 part of stevioside, 0.08 part of xylitol, 72 parts of deionized waters, 0.15 part of antiseptic.
Further, it is preferably invented as anti-inflammation collutory of the present invention, it is characterized in that the component that contains following parts by weight: 58 parts of honey combs, 9.5 parts of natural ripe Mel, 1.8 parts of Herba Menthaes, 7.1 parts of Fructus Momordicaes, 6.4 parts of sorbitol, 0.05 part of Aspartame, 0.05 part of acesulfame potassium, 0.05 part of stevioside, 0.05 part of xylitol, 80 parts of deionized waters, 0.2 part of antiseptic.
The present invention also provides a kind of preparation method of anti-inflammation collutory, it is characterized in that comprising the following steps:
(1) by after honey comb freezing and pulverizing, add water boil 2 ~ 3h, cooling, filter and remove upper strata Cera Flava and lower floor's residue, then vacuum concentration, thickening temperature is 50 ~ 60 ℃, then adds wherein natural ripe Mel, stirs, and obtains honeycomb vegetarian;
(2) by Fructus Momordicae chopping, infusion 10 ~ 12 minutes, is filtered, and vacuum concentration is concentrated, and thickening temperature is 50 ~ 60 ℃, obtains Fructus Momordicae extracting solution;
(3) Herba Menthae is smashed to pieces, through water extraction, then vacuum concentration, thickening temperature is 50 ~ 60 ℃, obtains Herba Menthae extracting solution;
(4) sorbitol, sweeting agent are dissolved in deionized water, and then the Herba Menthae extracting solution that adds wherein honeycomb vegetarian concentrated solution that step (1) obtains, Fructus Momordicae extracting solution that step (2) obtains and step (3) to obtain, stir, then add antiseptic, continue to stir, obtain mixed material;
(5) by mixed material filtration, aseptic process, obtain finished product of the present invention finished product of the present invention.
Action principle of the present invention:
1. in the present invention, select honey comb to make honeycomb vegetarian as one of main active of collutory of the present invention, this is because honeycomb vegetarian mainly contains the trace element such as propolis, the occurring in nature of Lac regis apis, natural antiinflammation rare anticancer Fungicidal substance 10-hydroxyl decanoic acid (being commonly called as Royal Jelly acid), Cera Flava, resin, multiple globulin, flavonoid, armaticity aldehydes, alcohols, various compound enzyme, aminoacid, vitamin, natural pigment, tannin, saccharide, glycoside and ferrum, calcium, copper, potassium.Medical science research finds, honeycomb vegetarian not only has the stronger dental caries ability that presses down, and can also have good result for the various rhinitis for the treatment of, pharyngolaryngitis, can alleviate rapidly because of symptoms such as nasal obstruction that all kinds of rhinitis cause, watery nasal discharge, headache, dizziness, throat discomforts.
Nasopharyngitis is the illness that nasal cavity, pharyngolaryngeal mucosa are inflamed, and morbidity main cause is due to antibacterial infection and immunity hypofunction.The materials such as the propolis in honeycomb vegetarian have and suppress and killing action antibacterial, fungus, virus, and royal jelly, pollen compound nutritional composition in honeycomb vegetarian fully promote immune function of human body to improve, and can make nasopharyngitis patient remission and disappear.Honeycomb vegetarian is the focuses of going directly from inside to outside for various rhinitis, and effect is rapid.
2. in the present invention, selecting Fructus Momordicae extracting solution as one of main active, is because Fructus Momordicae energy lung heat clearing intestine moistening cures mainly pertussis, phlegm-fire cough, the diseases such as the dry constipation of blood; For treatment acute tracheitis, acute tonsillitis, throat fire, acute gastritis has good curative effect.
3. in the present invention, select Herba Menthae extracting solution as one of main active, be because Herba Menthae can not only cleaning throat and moistening larynx, eliminate halitosis, can also suppress fever and mucosa inflammation, and promote perspire, there is good antiviral, sterilization, cough-relieving effect, for dry cough, asthma, bronchitis, pneumonia, pulmonary tuberculosis, there is certain curative effect.Meanwhile, the effect of the relieveing pain and refreshing of Herba Menthae eases toothache.
Therefore, collutory of the present invention, under various active composition synergism, has cleaning throat and moistening larynx, eliminates halitosis, anti-inflammation and sterilization, prevents and treats the multi-efficiencies such as dental caries, also rhinitis, pharyngolaryngitis, cough, have a toothache etc. is had to good adjuvant treatment effect simultaneously.
The present invention compared with prior art, its beneficial effect is: (1) product of the present invention adopts natural material as active component, under their combined effect, make the present invention there is cleaning throat and moistening larynx, eliminate halitosis, anti-inflammation and sterilization, prevent and treat the multi-efficiencies such as dental caries, sterilizing rate >=90%; (2) the present invention adopts Nidus Vespae usually to prevent and treat dental caries, has avoided using fluorine-containing chemical combination as pressing down the injury to human body such as fluorosis that dental caries agent brings; (3) the present invention has good adjuvant treatment effect for rhinitis, pharyngolaryngitis, cough, have a toothache etc.; (4) this product preparation method is simple, is easy to apply.
Specific embodiment
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 50 ~ 60 parts of honey combs, 6 ~ 10 parts of natural ripe Mel, 1 ~ 2 part of Herba Menthae, 6 ~ 8 parts of Fructus Momordicaes, 2 ~ 8 parts of sorbitol, 0.05 ~ 0.2 part of sweeting agent, 70 ~ 80 parts of deionized waters, 0.1 ~ 0.2 part of antiseptic.
Described sweeting agent is one or more in Aspartame, acesulfame potassium, stevioside, xylitol.Described honey comb is selected 3 years honey combs that do not go mouldy above.
The present invention also provides a kind of preparation method of anti-inflammation collutory, comprises the following steps:
(1) by after honey comb freezing and pulverizing, add water boil 2 ~ 3h, cooling, filter and remove upper strata Cera Flava and lower floor's residue, then vacuum concentration under 50 ~ 60 ℃ of conditions, then add wherein natural ripe Mel, and stir, obtain honeycomb vegetarian;
(2) by Fructus Momordicae chopping, infusion 10 ~ 12 minutes, is filtered, and then vacuum concentration under 50 ~ 60 ℃ of conditions, obtains Fructus Momordicae extracting solution;
(3) Herba Menthae is smashed to pieces, through water extraction, then vacuum concentration under 50 ~ 60 ℃ of conditions, obtains Herba Menthae extracting solution;
(4) sorbitol, sweeting agent are dissolved in deionized water, and then the Herba Menthae extracting solution that adds wherein honeycomb vegetarian concentrated solution that step (1) obtains, Fructus Momordicae extracting solution that step (2) obtains and step (3) to obtain, stir, then add antiseptic, continue to stir, obtain mixed material;
(5) by mixed material filtration, aseptic process, obtain finished product of the present invention.
Below in conjunction with the specific embodiment, the invention will be further described.
Embodiment 1
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 50 parts of honey combs, 6 parts of natural ripe Mel, 1 part of Herba Menthae, 6 parts of Fructus Momordicaes, 2 parts of sorbitol, 0.05 part of acesulfame potassium, 70 parts of deionized waters, 0.1 part of potassium sorbate.
A preparation method for anti-inflammation collutory, comprises the following steps:
(1) by after honey comb freezing and pulverizing, add water boil 2 ~ 3h, cooling, filter and remove upper strata Cera Flava and lower floor's residue, then vacuum concentration under 50 ~ 60 ℃ of conditions, then add wherein natural ripe Mel, and stir, obtain honeycomb vegetarian;
(2) by Fructus Momordicae chopping, infusion 10 ~ 12 minutes, is filtered, and then vacuum concentration under 50 ~ 60 ℃ of conditions, obtains Fructus Momordicae extracting solution;
(3) Herba Menthae is smashed to pieces, through water extraction, then vacuum concentration under 50 ~ 60 ℃ of conditions, obtains Herba Menthae extracting solution;
(4) sorbitol, sweeting agent are dissolved in deionized water, and then the Herba Menthae extracting solution that adds wherein honeycomb vegetarian concentrated solution that step (1) obtains, Fructus Momordicae extracting solution that step (2) obtains and step (3) to obtain, stir, then add antiseptic, continue to stir, obtain mixed material;
(5) by mixed material filtration, aseptic process, obtain finished product of the present invention.
Embodiment 2
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 60 parts of honey combs, 10 parts of natural ripe Mel, 2 parts of Herba Menthaes, 8 parts of Fructus Momordicaes, 8 parts of sorbitol, 0.2 part of xylitol, 80 parts of deionized waters, 0.2 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 3
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 52 parts of honey combs, 8 parts of natural ripe Mel, 1.3 parts of Herba Menthaes, 6.8 parts of Fructus Momordicaes, 4.6 parts of sorbitol, 0.15 part of stevioside, 71 parts of deionized waters, 0.15 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 4
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 53 parts of honey combs, 9.3 parts of natural ripe Mel, 1.1 parts of Herba Menthaes, 7.4 parts of Fructus Momordicaes, 7.5 parts of sorbitol, 0.06 part of Aspartame, 0.06 part of acesulfame potassium, 70 ~ 80 parts of deionized waters, 0.15 part of sodium benzoate.
Its preparation method is identical with embodiment 1.
Embodiment 5
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 56 parts of honey combs, 8.7 parts of natural ripe Mel, 1.3 parts of Herba Menthaes, 7.6 parts of Fructus Momordicaes, 5.8 parts of sorbitol, 0.06 part of Aspartame, 0.12 part of stevioside, 77 parts of deionized waters, 0.17 part of sodium benzoate.
Its preparation method is identical with embodiment 1.
Embodiment 6
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 58 parts of honey combs, 6.2 parts of natural ripe Mel, 1.4 parts of Herba Menthaes, 6.6 parts of Fructus Momordicaes, 3.8 parts of sorbitol, 0.08 part of Aspartame, 0.10 part of xylitol, 79 parts of deionized waters, 0.11 part of sodium benzoate.
Its preparation method is identical with embodiment 1.
Embodiment 7
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 58 parts of honey combs, 6.3 parts of natural ripe Mel, 1.6 parts of Herba Menthaes, 6.3 parts of Fructus Momordicaes, 3.5 parts of sorbitol, 0.08 part of acesulfame potassium, 0.07 part of xylitol, 72 parts of deionized waters, 0.2 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 8
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 55 parts of honey combs, 6.5 parts of natural ripe Mel, 1.8 parts of Herba Menthaes, 7.3 parts of Fructus Momordicaes, 4.5 parts of sorbitol, 0.08 part of acesulfame potassium, 0.09 part of stevioside, 72 parts of deionized waters, 0.12 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 9
A kind of anti-inflammation collutory, comprises the following component according to parts by weight meter: 55 parts of honey combs, 6.5 parts of natural ripe Mel, 1.8 parts of Herba Menthaes, 7.3 parts of Fructus Momordicaes, 4.5 parts of sorbitol, 0.05 part of acesulfame potassium, 0.06 part of stevioside, 0.06 part of xylitol, 72 parts of deionized waters, 0.12 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 10
Anti-inflammation collutory of the present invention, the component that contains following parts by weight: 50 parts of honey combs, 7 parts of natural ripe Mel, 1.5 parts of Herba Menthaes, 8 parts of Fructus Momordicaes, 4 parts of sorbitol, 0.1 part of Aspartame, 70 parts of deionized waters, 0.12 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
Embodiment 11
Anti-inflammation collutory of the present invention, the component that contains following parts by weight: 54 parts of honey combs, 8 parts of natural ripe Mel, 2 parts of Herba Menthaes, 6.8 parts of Fructus Momordicaes, 5.5 parts of sorbitol, 0.05 part of stevioside, 0.08 part of xylitol, 72 parts of deionized waters, 0.15 part of sodium benzoate.
Its preparation method is identical with embodiment 1.
Embodiment 12
Anti-inflammation collutory of the present invention, the component that contains following parts by weight: 58 parts of honey combs, 9.5 parts of natural ripe Mel, 1.8 parts of Herba Menthaes, 7.1 parts of Fructus Momordicaes, 6.4 parts of sorbitol, 0.05 part of Aspartame, 0.05 part of acesulfame potassium, 0.05 part of stevioside, 0.05 part of xylitol, 80 parts of deionized waters, 0.2 part of potassium sorbate.
Its preparation method is identical with embodiment 1.
This test adopts conventional microbial disinfection effect detection, detects embodiment 1 ~ 12 and matched group, and wherein matched group is commercially available a kind of collutory, and its sterilizing power result is as shown in table 1.
Table 1 anti-inflammation collutory sterilization of the present invention testing result
| ? | Staphylococcus aureus | Candida albicans | Escherichia coli | Streptococcus mutans |
| Matched group | 88.5% | 86.4% | 89.7% | 89.9% |
| Embodiment 1 | 95.5% | 94.6% | 95.1% | 95.2% |
| Embodiment 2 | 95.3% | 96.5% | 95.0% | 95.5% |
| Embodiment 3 | 97.4% | 97.3% | 95.5% | 97.3% |
| Embodiment 4 | 96.5% | 96.7% | 96.3% | 98.1% |
| Embodiment 5 | 98.2% | 98.1% | 97.4% | 96.7% |
| Embodiment 6 | 98.4% | 97.9% | 96.9% | 98.0% |
| Embodiment 7 | 97.5% | 98.3% | 98.1% | 97.8% |
| Embodiment 8 | 96.8% | 98.7% | 97.9% | 98.5% |
| Embodiment 9 | 98.9% | 97.6% | 98.7% | 98.1% |
| Embodiment 10 | 99.0% | 99.2% | 98.9% | 99.2% |
| Embodiment 11 | 99.6% | 98.9% | 99.2% | 98.9% |
| Embodiment 12 | 98.8% | 99.6% | 99.4% | 99.0% |
Studied product of the present invention to halitosis removal effect simultaneously, used continuously product of the present invention one week, after morning, noon, dinner, used this collutory, used inspection socket cavity foreign flavor situation after 3 hours, its result is as shown in table 2.
This product of table 2 is removed result to halitosis
| ? | Matched group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| Clearance | 68% | 92% | 90% | 95% | 98% | 96% | 94% |
| ? | Embodiment 7 | Embodiment 8 | Embodiment 9 | Embodiment 10 | Embodiment 11 | Embodiment 12 | ? |
| Clearance | 98% | 99% | 99% | 100% | 100% | 100% | ? |
Claims (7)
1. an anti-inflammation collutory, is characterized in that comprising that the component according to parts by weight meter is as follows: 50 ~ 60 parts of honey combs, 6 ~ 10 parts of natural ripe Mel, 1 ~ 2 part of Herba Menthae, 6 ~ 8 parts of Fructus Momordicaes, 2 ~ 8 parts of sorbitol, 0.05 ~ 0.2 part of sweeting agent, 70 ~ 80 parts of deionized waters, 0.1 ~ 0.2 part of antiseptic.
2. anti-inflammation collutory according to claim 1, is characterized in that described sweeting agent is one or more in Aspartame, acesulfame potassium, stevioside, xylitol.
3. anti-inflammation collutory according to claim 1, the honey comb described in it is characterized in that is selected 3 years honey combs that do not go mouldy above.
4. anti-inflammation collutory according to claim 2, is characterized in that comprising that the component according to parts by weight meter is as follows: 50 parts of honey combs, 7 parts of natural ripe Mel, 1.5 parts of Herba Menthaes, 8 parts of Fructus Momordicaes, 4 parts of sorbitol, 0.1 part of Aspartame, 70 parts of deionized waters, 0.12 part of antiseptic.
5. anti-inflammation collutory according to claim 2, is characterized in that comprising that the component according to parts by weight meter is as follows: 54 parts of honey combs, 8 parts of natural ripe Mel, 2 parts of Herba Menthaes, 6.8 parts of Fructus Momordicaes, 5.5 parts of sorbitol, 0.05 part of stevioside, 0.08 part of xylitol, 72 parts of deionized waters, 0.15 part of antiseptic.
6. anti-inflammation collutory according to claim 2, is characterized in that comprising that the component according to parts by weight meter is as follows: 58 parts of honey combs, 9.5 parts of natural ripe Mel, 1.8 parts of Herba Menthaes, 7.1 parts of Fructus Momordicaes, 6.4 parts of sorbitol, 0.05 part of Aspartame, 0.05 part of acesulfame potassium, 0.05 part of stevioside, 0.05 part of xylitol, 80 parts of deionized waters, 0.2 part of antiseptic.
7. the preparation method of anti-inflammation collutory claimed in claim 1, is characterized in that comprising the following steps:
(1) by after honey comb freezing and pulverizing, add water boil 2 ~ 3h, cooling, filter and remove upper strata Cera Flava and lower floor's residue, then vacuum concentration, thickening temperature is 50 ~ 60 ℃, then adds wherein natural ripe Mel, stirs, and obtains honeycomb vegetarian;
(2) by Fructus Momordicae chopping, infusion 10 ~ 12 minutes, is filtered, and vacuum concentration is concentrated, and thickening temperature is 50 ~ 60 ℃, obtains Fructus Momordicae extracting solution;
(3) Herba Menthae is smashed to pieces, through water extraction, then vacuum concentration, thickening temperature is 50 ~ 60 ℃, obtains Herba Menthae extracting solution;
(4) sorbitol, sweeting agent are dissolved in deionized water, and then the Herba Menthae extracting solution that adds wherein honeycomb vegetarian concentrated solution that step (1) obtains, Fructus Momordicae extracting solution that step (2) obtains and step (3) to obtain, stir, then add antiseptic, continue to stir, obtain mixed material;
(5) by mixed material filtration, aseptic process, obtain finished product of the present invention.
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| CN106309331A (en) * | 2016-10-14 | 2017-01-11 | 柳州环山科技有限公司 | Mouth wash used in female physiological period and preparation method thereof |
| CN107693442A (en) * | 2017-09-14 | 2018-02-16 | 南通荣成医药化工有限公司 | A kind of efficient sterilizing mouthwash |
| CN107648130A (en) * | 2017-11-17 | 2018-02-02 | 蚌埠崇迪生物科技有限公司 | A kind of anti-inflammation gargle water and preparation method thereof |
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Application publication date: 20140423 |