CN1608610A - Prepn process of concentrated bee glue gargle - Google Patents
Prepn process of concentrated bee glue gargle Download PDFInfo
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- CN1608610A CN1608610A CNA2003101019613A CN200310101961A CN1608610A CN 1608610 A CN1608610 A CN 1608610A CN A2003101019613 A CNA2003101019613 A CN A2003101019613A CN 200310101961 A CN200310101961 A CN 200310101961A CN 1608610 A CN1608610 A CN 1608610A
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- propolis
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- collutory
- xylitol
- distilled water
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Abstract
The present invention is concentrated gargle compounded with bee glue and xylitol as natural non-toxic food without stimulation to oral cavity mucous membrane. The concentrated gargle is fragrant, tasty and refreshing, and has the functions of cleaning oral cavity, eliminating halitosis, diminishing inflammation, protecting teeth, and preventing and treating oral diseases, such as gingivitis, peridentitis, etc. The present invention is one oral cleaning article with high efficiency.
Description
(1) technical field
The present invention relates to the preparation method of a kind of tooth or cleaning agent for mouth cavity.Be the concentrated collutory of main component preparation specifically with propolis, xylitol.
(2) background technology
The whole nation oral health epidemiological survey report second time that whole nation dental prevention group carries out shows that the adult of China 82% has the gingival atrophy phenomenon, and gingival atrophy causes the arch-criminal of root dental caries just.Dental caries is a department of stomatology commonly encountered diseases, and caries prevalence rate can reach 30%～95%.The principal element that causes dental caries is a bacterial infection, and in the flora of dental plaque, Streptococcus mutans can carry out anaerobic metabolism in dental plaque, and fermentation and acid becomes the main pathogenic bacterium of dental caries.Therefore, suppress or kill the key that Streptococcus mutans in the dental plaque becomes the control dental caries.
Propolis is the more natural auti-cariosity material of Recent study, biological actions such as having antibiotic, antioxidation, press down enzyme, be conjugated protein.Existing many studies confirm that, propolis can suppress or kill Streptococcus mutans and other anaerobe in the dental plaque, thereby reaches the purpose of preventing and treating oral disease.
Xylitol is a kind of natural sweetener that can extract from plants such as silver birch, Oak Tree, corn.Last century six the seventies, the Finland scientist discovers, xylitol can not produced the acidic materials that cause dental caries by decayed tooth bacterium (denatured strand coccus) fermentation, the nutrition that it can not provide antibacterial to depend on for existence, find also that in recent years xylitol is to the also helpful effect that it is repaired naturally of early stage dental caries.
It is nontoxic, formulated to the non-stimulated natural health care of oral mucosa that the present invention selects for use.Have fragrance tasty and refreshing, cleaning oral cavity, elimination halitosis, anti-inflammation, take care of one's teeth, prevent and treat oral disease; as dental caries, periodontitis, stomatitis, pharyngolaryngitis; that its advantage is to use is easy, save time, and does not need special apparatus, is a kind of very effective dental care products.
(3) summary of the invention
Technical solution of the present invention has provided the preparation method that a kind of propolis concentrates collutory, and said composition contains the component of following portions by weight,
Ingredients weight parts
Propolis 0.5-8
Xylitol 5-15
Polyethylene Glycol 1-7
Propylene glycol 10-70
Adopt Polyethylene Glycol can increase the penetration capacity of principal agent to oral mucosa in the prescription, make principal agent better bring into play curative effect, propylene glycol has moist ulcer surface, adheres to medicine the medicine slow release is come out, and prolongs and strengthen the curative effect of medicine.
2) preparation method:
Propolis in the above-mentioned prescription, xylitol and suitable emulsifying agent is evenly mixed in rustless steel or glass blending tank, add correctives and the distilled water back that stirs then.
Mentioned emulsifier is one or more in propylene glycol, Polyethylene Glycol (molecular weight 200-6000), glycerol, ethylhydroxyethylcellulose, methylcellulose, glyceryl monostearate, hydroxylated lecithin, acetylated monoglyceride, orthoformic acid, casein, ethylene glycol monostearate, diacetyl monoglyceride, acetic acid one fatty glyceride, Emulsifier LM-102, propylene glycol alginate, the ethanol.
Above-mentioned correctives is one or more in Mentholum, eucalyptus oil, white lemon oil, Fructus Dauci Sativae oil, Oleum menthae, castoreum, Oleum menthae, Fructus Citri Limoniae oil, citronella oil, machilus leaf oil, carnation absolute, Radix Buddlejae Butterflybush extractum, Oleum Camphora, natural vanillin, edible flavoring orange oil essence, edible flavoring pineapple oil essence, food lemon oily flavor, the champignon oil essence.
Get above-mentioned concentrated solution portion during use, add 35-40 part water.It is muddy that solution after the dilution will become, and oneself can use this collutory of prompting user.Then, the solution of user after with about 20 milliliters dilution spues after gargling and washing the oral cavity again.
(4) specific embodiment
Embodiment 1
1) prescription
Ingredients weight parts
Propolis 1
Xylitol 8
Polyethylene Glycol (molecular weight 6000) 6
Propylene glycol 55
Glycerol 10
Mentholum 0.03
Distilled water 10
Adopt Polyethylene Glycol can increase the penetration capacity of principal agent to oral mucosa in the prescription, make principal agent better bring into play curative effect, glycerol has moist ulcer surface, adheres to medicine the medicine slow release is come out, and prolongs and strengthen the curative effect of medicine;
2) preparation method:
Polyethylene Glycol in the above-mentioned prescription (molecular weight 6000) is dissolved in the distilled water of portion of hot, again propolis, propylene glycol, glycerol and its is evenly mixed, add xylitol, Mentholum and the remaining distilled water back that stirs then.
This product is brown clear liquid, fragrant odour, and it is sweet slightly bitter to distinguish the flavor of, the refrigerant sense of having gargled.
Embodiment 2
1) prescription
Ingredients weight parts
Propolis 0.5
Xylitol 6
Polyethylene Glycol (molecular weight 6000) 6
Propylene glycol 67
Natural vanillin 0.5
Distilled water 20
2) preparation method:
Polyethylene Glycol in the above-mentioned prescription (molecular weight 6000) is dissolved in the distilled water of portion of hot, again propolis, propylene glycol and its is evenly mixed, add natural vanillin, xylitol and the remaining distilled water back that stirs then.
This product is brown clear liquid, fragrant odour, and it is sweet slightly bitter to distinguish the flavor of, the refrigerant sense of having gargled.
Embodiment 3
1) prescription
Ingredients weight parts
Propolis 0.5
Xylitol 6
Polyethylene Glycol (molecular weight 6000) 1
Propylene glycol 15
Ethanol 10
Food lemon oily flavor 0.05
Distilled water 77.5
2 preparation methoies:
With the propolis in the above-mentioned prescription, xylitol and propylene glycol, glycerol in rustless steel or glass blending tank mixed evenly, add stir back of Mentholum and distilled water then.
Polyethylene Glycol in the above-mentioned prescription (molecular weight 6000) is dissolved in the distilled water of portion of hot, again propolis, ethanol, propylene glycol and its is evenly mixed, add xylitol, food lemon oily flavor and the remaining distilled water back that stirs then.
This product is brown clear liquid, fragrant odour, and it is sweet slightly bitter to distinguish the flavor of, the refrigerant sense of having gargled.
Claims (4)
1. the preparation method of the concentrated collutory of propolis is characterized in that said composition contains the component of following portions by weight,
Ingredients weight parts
Propolis 0.5-8
Xylitol 3-15
Propylene glycol 50-75
Polyethylene Glycol (molecular weight 6000) 4-10
Mentholum 0.01-0.05
Distilled water 10-20
2. a kind of propolis as claimed in claim 1 concentrates the preparation method of collutory, it is characterized in that the optimization formula of said composition is as follows:
Ingredients weight parts
Propolis 0.5
Xylitol 4.5
Propylene glycol 70
Polyethylene Glycol (molecular weight 6000) 6
Mentholum 0.03
Distilled water 19
3. a kind of propolis as claimed in claim 1 concentrates the preparation method of collutory, it is characterized in that its dosage form is the concentrated type collutory, needs dilution 35-40 doubly to use the back.
4. a kind of propolis as claimed in claim 1 concentrates the preparation method of collutory, it is characterized in that preparation method is as follows:
Polyethylene Glycol in the above-mentioned prescription (molecular weight 6000) is dissolved in the distilled water of portion of hot, again with propolis, propylene glycol, evenly mixed, adds xylitol, Mentholum and the remaining distilled water back that stirs then with it.This product is brown clear liquid, fragrant odour, and it is sweet slightly bitter to distinguish the flavor of, the refrigerant sense of having gargled.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101019613A CN100336499C (en) | 2003-10-20 | 2003-10-20 | Prepn process of concentrated bee glue gargle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101019613A CN100336499C (en) | 2003-10-20 | 2003-10-20 | Prepn process of concentrated bee glue gargle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1608610A true CN1608610A (en) | 2005-04-27 |
| CN100336499C CN100336499C (en) | 2007-09-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2003101019613A Expired - Fee Related CN100336499C (en) | 2003-10-20 | 2003-10-20 | Prepn process of concentrated bee glue gargle |
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| CN (1) | CN100336499C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100398091C (en) * | 2005-05-20 | 2008-07-02 | 远景生物科技（上海）有限公司 | An anti-cavity toothpaste with natural substances for children and method for making same |
| CN1857194B (en) * | 2006-03-03 | 2010-12-22 | 田昆 | Compound Tala gargle and its preparing process |
| CN103735481A (en) * | 2013-06-29 | 2014-04-23 | 明光市昊昊蜂业有限公司 | Antisepsis and anti-inflammation mouth rinse and preparation method thereof |
| CN105998549A (en) * | 2016-06-29 | 2016-10-12 | 何勤 | Traditional Chinese medicine compound for treating chronic periodontitis |
| CN106727249A (en) * | 2017-02-21 | 2017-05-31 | 糖友管家（北京）健康管理有限公司 | A kind of mouthwash and preparation method thereof |
| CN107184530A (en) * | 2017-05-24 | 2017-09-22 | 深圳市欧斯特尔实业有限公司 | A kind of mouthwash and preparation method thereof |
| CN107929217A (en) * | 2018-01-22 | 2018-04-20 | 郭心畅 | Propolis herbal mouthwash |
| CN110755355A (en) * | 2019-08-06 | 2020-02-07 | 江苏蜂奥生物科技有限公司 | Propolis toothpaste and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK200000413A (en) * | 2000-03-14 | 2000-03-14 | Novo Nordisk As | Oral care compositions comprising enzymes with anti-halitosis or plaque removing activity |
| AU2003206183A1 (en) * | 2002-01-26 | 2003-09-02 | Micro Science Tech Co., Ltd | Composition containing moutan root bark extract as active ingredient |
-
2003
- 2003-10-20 CN CNB2003101019613A patent/CN100336499C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100398091C (en) * | 2005-05-20 | 2008-07-02 | 远景生物科技（上海）有限公司 | An anti-cavity toothpaste with natural substances for children and method for making same |
| CN1857194B (en) * | 2006-03-03 | 2010-12-22 | 田昆 | Compound Tala gargle and its preparing process |
| CN103735481A (en) * | 2013-06-29 | 2014-04-23 | 明光市昊昊蜂业有限公司 | Antisepsis and anti-inflammation mouth rinse and preparation method thereof |
| CN105998549A (en) * | 2016-06-29 | 2016-10-12 | 何勤 | Traditional Chinese medicine compound for treating chronic periodontitis |
| CN106727249A (en) * | 2017-02-21 | 2017-05-31 | 糖友管家（北京）健康管理有限公司 | A kind of mouthwash and preparation method thereof |
| CN106727249B (en) * | 2017-02-21 | 2020-12-08 | 糖友管家（北京）健康管理有限公司 | Mouthwash and preparation method thereof |
| CN107184530A (en) * | 2017-05-24 | 2017-09-22 | 深圳市欧斯特尔实业有限公司 | A kind of mouthwash and preparation method thereof |
| CN107929217A (en) * | 2018-01-22 | 2018-04-20 | 郭心畅 | Propolis herbal mouthwash |
| CN110755355A (en) * | 2019-08-06 | 2020-02-07 | 江苏蜂奥生物科技有限公司 | Propolis toothpaste and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100336499C (en) | 2007-09-12 |
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