CN107496267A - A kind of acne-eliminating cosmetic and preparation method thereof - Google Patents

A kind of acne-eliminating cosmetic and preparation method thereof Download PDF

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CN107496267A
CN107496267A CN201710968917.4A CN201710968917A CN107496267A CN 107496267 A CN107496267 A CN 107496267A CN 201710968917 A CN201710968917 A CN 201710968917A CN 107496267 A CN107496267 A CN 107496267A
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acne
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陈兴建
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Foshan Feishida New Mstar Technology Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • A61K2800/72Hypo-allergenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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Abstract

A kind of preparation method of acne-eliminating cosmetic of the present invention, weighs selfheal, radix tetrastigme, radix glycyrrhizae and radix scutellariae, crushes and adds the ethanol that volume fraction is 85% and soak 24 72h at 50 70 DEG C of temperature, filters, collect filtrate;By ethanol that dregs of a decoction volume fraction is 95% in 60 80 DEG C of 8h of refluxing extraction 5 of temperature, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.2 0.5g/ml decoction;Methyl hydroxybenzoate, butanediol, isononyl isononanoate, glycine betaine salicylate are mixed, are heated with stirring to 70 90 DEG C, the 40min of insulation reaction 20;Then rise temperature adds niacinamide and dimethyl silicone polymer continues the 45min of stirring reaction 30 to 95 115 DEG C;Sorbierite and ethoxy urea are added in gained material, stirring cooling, rate of temperature fall is 12 DEG C/min, when being cooled to 50 55 DEG C, adds decoction thereto, insulated and stirred reacts 20 30min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.

Description

A kind of acne-eliminating cosmetic and preparation method thereof
Technical field
The invention belongs to cosmetic field, more particularly to a kind of acne-eliminating cosmetic and preparation method thereof.
Background technology
Acne (Acne) is acne vulgaris, is commonly called as " acne ", " whelk ", " acne " or " wine pimple ", is a kind of Common hair follicle, sebaceous glands chronic inflammatory diseases caused by many factors comprehensive function are most of youth of both sexes in Paederus fuscipes Curtis More universal disease of skin existing for phase, the epidemiology survey that China is made recently show that 44.5% teenager suffers from Cuo Sore.Acne clinic is with the characteristics of face and chest and back are dispersed in the skin disease that needle point grain of rice size occurs, or sees blackhead, can extrude granulated slag Rash and useless fellow in sample thing, first meeting such as tiny mound, with tubercle, tumour, scar, pigmentation when serious.It is not only one kind Physical disease, and a kind of psychosomatic disease that can not be ignored, all have an impact to patient in social, psychology, mood etc..Mesh Before, the treatment to whelk is generally by taking vitamin, endocrine preparation and antibiotic, the outer method for wiping cream, but effect orally It is not ideal enough, cause whelk flickering, repeated, it is difficult to eradicate.
The disclosed patent document for having correlation in the prior art, such as:Chinese patent literature (201410453602.2) carries The essential oils of herbs anti-acne soap of confession, by wormwood soak, wormwood powder, evening primrose oil, tea tree ethereal oil, OPC, pure water, Vitamin E, olive oil, palm oil and coconut oil composition, although having reached promoting blood circulation toxin expelling, the effect of Glycerin, due to Play that the medicinal herb componentses of acne-removing are seldom in its composition, although there is certain toxin expelling effect, generally anti-acne effect is bad, It really can't resolve acne puzzlement.Current anti-acne soap product, to improve anti-acne effect, often add to skin spinosity Swash the chemical raw material of effect, long-term use makes chapped skin, aggravated acne on the contrary, it is therefore desirable to provide a kind of composition it is gentle, It is low stimulate, can effective anti-acne product.
The content of the invention
It is a variety of by adding it is an object of the invention to provide a kind of preparation method of acne-eliminating cosmetic for drawbacks described above Effective traditional Chinese medicine ingredients simultaneously add a variety of modifying agent, so obtained composition it is gentle, it is low stimulate, the product of anti-acne efficiency high.
A kind of preparation method of acne-eliminating cosmetic, is comprised the following steps:
(1) 5-10 parts selfheal, 3-7 parts radix tetrastigme, 10-15 parts radix glycyrrhizae and 8-10 part radix scutellariaes are weighed, is crushed to 40-80 Mesh, add ethanol that 10-12 times of volume fraction measured is 85% and soak 24-72h at 50-70 DEG C of temperature, filter, collect filter Liquid;By the dregs of a decoction with the ethanol that the 8-10 times of volume fraction measured is 95% in 60-80 DEG C of refluxing extraction 5-8h of temperature, filtering, merging Filtrate twice, it is concentrated under reduced pressure into 0.2-0.5g/ml decoction;
(2) by 7-12 parts methyl hydroxybenzoate, 10-20 parts butanediol, 5-10 parts isononyl isononanoate, 6-12 part glycine betaine bigcatkin willows Hydrochlorate mixes, and is heated with stirring to 70-90 DEG C, insulation reaction 20-40min;Then rise temperature adds 6-12 parts to 95-115 DEG C Niacinamide and 4-10 parts dimethyl silicone polymer continue stirring reaction 30-45min;
(3) 7-10 parts sorbierite and 4-8 part ethoxys urea are added in step (2) in gained material, with speed 2000- 3000r/min starts stirring cooling, and rate of temperature fall is 1-2 DEG C/min, when being cooled to 50-55 DEG C, adds step (1) thereto Gained material, insulated and stirred reaction 20-30min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
Preferably, 8 portions of selfheals, 6 portions of radix tetrastigmes, 12 portions of radix glycyrrhizaes and 9 parts of radix scutellariaes are weighed in step (1), are crushed to 60 mesh, The ethanol that the volume fractions for adding 11 times of amounts are 85% soaks 48h at 65 DEG C of temperature.
Preferably, in step (1) by the dregs of a decoction with 9 times amount volume fractions be 95% ethanol in 75 DEG C of refluxing extractions of temperature 6.5h, it is concentrated under reduced pressure into 0.35g/ml decoction.
Preferably, by 10 parts of methyl hydroxybenzoates, 15 parts of butanediols, 7 parts of isononyl isononanoates, 10 parts of glycine betaines in step (2) Salicylate mixes, and is heated with stirring to 80 DEG C, insulation reaction 30min.
Preferably, then rise temperature to 105 DEG C, adds 10 parts of niacinamide and 8 parts of polydimethylsiloxanes described in rapid (2) Alkane continues stirring reaction 40min.
Preferably, 8 parts of sorbierites and 6 parts of ethoxy urea are added in step (2) in gained material in step (3), with Speed 2500r/min starts stirring cooling, and rate of temperature fall is 1.5 DEG C/min, when being cooled to 52 DEG C, adds step thereto (1) gained material, insulated and stirred reaction 28min.
A kind of above-mentioned any one described acne-eliminating cosmetic being prepared.
Compared with prior art, its advantage is the present invention:
The preparation method of a kind of acne-eliminating cosmetic of the present invention, by extracting selfheal, radix tetrastigme, radix glycyrrhizae and radix scutellariae etc. Traditional Chinese medicine ingredients are as anti-acne composition main body;Simultaneously with methyl hydroxybenzoate, butanediol, isononyl isononanoate, glycine betaine salicylate etc. Material has obtained that anti-acne effect is good, composition is gentle, the Novel acne treatment cosmetics of low stimulation as cosmetic base.Dispelling During acne traditional Chinese medicine ingredients and cosmetic base merge, using modes such as heating-insulation-cooling-insulations, gradually fusion, makes The cosmetics homogenieity that must be formed is good.
Embodiment
The present invention is further illustrated with reference to embodiments.
Embodiment 1
(1) 5 portions of selfheals, 3 portions of radix tetrastigmes, 10 portions of radix glycyrrhizaes and 10 parts of radix scutellariaes are weighed, are crushed to 40 mesh, 10 times of amounts of addition The ethanol that volume fraction is 85% soaks 72h under temperature 70 C, filters, and collects filtrate;Volume fraction by the dregs of a decoction with 8 times of amounts For 95% ethanol in temperature 60 C refluxing extraction 5h, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.2g/ml decoction;
(2) 7 parts of methyl hydroxybenzoates, 10 parts of butanediols, 5 parts of isononyl isononanoates, 6 parts of glycine betaine salicylates are mixed, stirred Mix and be heated to 70 DEG C, insulation reaction 20min;Then rise temperature adds 6 parts of niacinamide and 4 parts of polydimethylsiloxanes to 95 DEG C Alkane continues stirring reaction 30min;
(3) 7 parts of sorbierites and 4 parts of ethoxy urea are added in step (2) in gained material, with speed 2000r/min Start stirring cooling, rate of temperature fall is 1 DEG C/min, when being cooled to 50 DEG C, adds material obtained by step (1), insulation thereto Stirring reaction 20min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
Embodiment 2
(1) 10 portions of selfheals, 7 portions of radix tetrastigmes, 15 portions of radix glycyrrhizaes and 8 parts of radix scutellariaes are weighed, are crushed to 80 mesh, 12 times of amounts of addition The ethanol that volume fraction is 85% soaks 24h under temperature 50 C, filters, and collects filtrate;Volume integral by the dregs of a decoction with 10 times of amounts Number for 95% ethanol in 80 DEG C of refluxing extraction 8h of temperature, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.5g/ml medicine Liquid;
(2) 12 parts of methyl hydroxybenzoates, 20 parts of butanediols, 10 parts of isononyl isononanoates, 12 parts of glycine betaine salicylates are mixed, 90 DEG C are heated with stirring to, insulation reaction 40min;Then rise temperature adds 12 parts of niacinamide and 10 parts of poly dimethyls to 115 DEG C Siloxanes continues stirring reaction 45min;
(3) 10 parts of sorbierites and 8 parts of ethoxy urea are added in step (2) in gained material, with speed 3000r/min Start stirring cooling, rate of temperature fall is 2 DEG C/min, when being cooled to 55 DEG C, adds material obtained by step (1), insulation thereto Stirring reaction 30min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
Embodiment 3
(1) 7 portions of selfheals, 6 portions of radix tetrastigmes, 14 portions of radix glycyrrhizaes and 8 parts of radix scutellariaes are weighed, are crushed to 50 mesh, 11 times of amounts of addition The ethanol that volume fraction is 85% soaks 32h at 65 DEG C of temperature, filters, and collects filtrate;Volume fraction by the dregs of a decoction with 9 times of amounts For 95% ethanol in 65 DEG C of refluxing extraction 6.5h of temperature, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.35g/ml medicine Liquid;
(2) 8 parts of methyl hydroxybenzoates, 12 parts of butanediols, 7 parts of isononyl isononanoates, 8 parts of glycine betaine salicylates are mixed, stirred Mix and be heated to 75 DEG C, insulation reaction 25min;Then rise temperature adds 8 parts of niacinamide and 5 parts of polydimethylsiloxanes to 100 DEG C Alkane continues stirring reaction 35min;
(3) 8 parts of sorbierites and 5 parts of ethoxy urea are added in step (2) in gained material, with speed 2500r/min Start stirring cooling, rate of temperature fall is 1 DEG C/min, when being cooled to 52 DEG C, adds material obtained by step (1), insulation thereto Stirring reaction 22min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
Embodiment 4
(1) 9 portions of selfheals, 4 portions of radix tetrastigmes, 12 portions of radix glycyrrhizaes and 9 parts of radix scutellariaes are weighed, are crushed to 70 mesh, 12 times of amounts of addition The ethanol that volume fraction is 85% soaks 48h under temperature 70 C, filters, and collects filtrate;Volume integral by the dregs of a decoction with 10 times of amounts Number for 95% ethanol in 75 DEG C of refluxing extraction 7.5h of temperature, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.45g/ml's Decoction;
(2) 10 parts of methyl hydroxybenzoates, 18 parts of butanediols, 9 parts of isononyl isononanoates, 10 parts of glycine betaine salicylates are mixed, 85 DEG C are heated with stirring to, insulation reaction 35min;Then rise temperature adds 10 parts of niacinamide and 8 parts of poly dimethyls to 110 DEG C Siloxanes continues stirring reaction 40min;
(3) 10 parts of sorbierites and 7 parts of ethoxy urea are added in step (2) in gained material, with speed 2800r/min Start stirring cooling, rate of temperature fall is 1.5 DEG C/min, when being cooled to 55 DEG C, adds material obtained by step (1) thereto, protects Warm stirring reaction 25min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
Embodiment 5
(1) 8 portions of selfheals, 6 portions of radix tetrastigmes, 12 portions of radix glycyrrhizaes and 9 parts of radix scutellariaes are weighed, are crushed to 60 mesh, 11 times of amounts of addition The ethanol that volume fraction is 85% soaks 48h at 65 DEG C of temperature, filters, and collects filtrate;Volume fraction by the dregs of a decoction with 9 times of amounts For 95% ethanol in 75 DEG C of refluxing extraction 6.5h of temperature, filtering, merge filtrate twice, be concentrated under reduced pressure into 0.35g/ml medicine Liquid;
(2) 10 parts of methyl hydroxybenzoates, 15 parts of butanediols, 7 parts of isononyl isononanoates, 10 parts of glycine betaine salicylates are mixed, 80 DEG C are heated with stirring to, insulation reaction 30min;Then rise temperature adds 10 parts of niacinamide and 8 parts of poly dimethyls to 105 DEG C Siloxanes continues stirring reaction 40min;
(3) 8 parts of sorbierites and 6 parts of ethoxy urea are added in step (2) in gained material, with speed 2500r/min Start stirring cooling, rate of temperature fall is 1.5 DEG C/min, when being cooled to 52 DEG C, adds material obtained by step (1) thereto, protects Warm stirring reaction 28min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
The acne-eliminating cosmetic performance test (each coating sooner or later daily is once) obtained to above-mentioned each embodiment, detailed results It see the table below:
Experiment The acne that disappears number of days Cure rate (%)
Embodiment 1 24 81.2
Embodiment 2 22 82.7
Embodiment 3 20 84.2
Embodiment 4 18 83.9
Embodiment 5 16 85.1
The invention is not restricted to embodiment here, those skilled in the art do not depart from the present invention according to the announcement of the present invention The improvement and modification that category is made all should be within protection scope of the present invention.

Claims (7)

1. a kind of preparation method of acne-eliminating cosmetic, it is characterised in that comprise the following steps:
(1) 5-10 parts selfheal, 3-7 parts radix tetrastigme, 10-15 parts radix glycyrrhizae and 8-10 part radix scutellariaes are weighed, 40-80 mesh is crushed to, adds Enter the ethanol that the 10-12 times of volume fraction measured is 85% and soak 24-72h at 50-70 DEG C of temperature, filter, collect filtrate;By medicine Slag in 60-80 DEG C of refluxing extraction 5-8h of temperature, filtering, merges filter twice with the ethanol that the 8-10 times of volume fraction measured is 95% Liquid, it is concentrated under reduced pressure into 0.2-0.5g/ml decoction;
(2) by 7-12 parts methyl hydroxybenzoate, 10-20 parts butanediol, 5-10 parts isononyl isononanoate, 6-12 part glycine betaine salicylates Mixing, is heated with stirring to 70-90 DEG C, insulation reaction 20-40min;Then rise temperature adds 6-12 part nicotinoyl to 95-115 DEG C Amine and 4-10 parts dimethyl silicone polymer continue stirring reaction 30-45min;
(3) 7-10 parts sorbierite and 4-8 part ethoxys urea are added in step (2) in gained material, with speed 2000- 3000r/min starts stirring cooling, and rate of temperature fall is 1-2 DEG C/min, when being cooled to 50-55 DEG C, adds step (1) thereto Gained material, insulated and stirred reaction 20-30min;Sterilizing, continues cooling and the acne-eliminating cosmetic is can obtain when room temperature.
2. the preparation method of a kind of acne-eliminating cosmetic according to claim 1, it is characterised in that step weighs 8 parts in (1) Selfheal, 6 portions of radix tetrastigmes, 12 portions of radix glycyrrhizaes and 9 parts of radix scutellariaes, 60 mesh are crushed to, the volume fraction for adding 11 times of amounts is 85% second Alcohol soaks 48h at 65 DEG C of temperature.
3. the preparation method of a kind of acne-eliminating cosmetic according to claim 1, it is characterised in that by the dregs of a decoction in step (1) The ethanol for being 95% with the volume fractions of 9 times of amounts is concentrated under reduced pressure into 0.35g/ml decoction in 75 DEG C of refluxing extraction 6.5h of temperature.
4. the preparation method of a kind of acne-eliminating cosmetic according to claim 1, it is characterised in that by 10 parts in step (2) Methyl hydroxybenzoate, 15 parts of butanediols, 7 parts of isononyl isononanoates, 10 parts of glycine betaine salicylate mixing, are heated with stirring to 80 DEG C, protect Temperature reaction 30min.
A kind of 5. preparation method of acne-eliminating cosmetic according to claim 1, it is characterised in that described in step (2) with Temperature is raised afterwards to 105 DEG C, adds 10 parts of niacinamide and 8 parts of dimethyl silicone polymers continue stirring reaction 40min.
6. the preparation method of a kind of acne-eliminating cosmetic according to claim 1, it is characterised in that by 8 parts of mountains in step (3) Pears alcohol and 6 parts of ethoxy urea are added in step (2) in gained material, start stirring cooling, cooling speed with speed 2500r/min Rate is 1.5 DEG C/min, when being cooled to 52 DEG C, adds material obtained by step (1), insulated and stirred reaction 28min thereto.
7. according to a kind of any one described acne-eliminating cosmetic being prepared of claim 1-6.
CN201710968917.4A 2017-10-18 2017-10-18 A kind of acne-eliminating cosmetic and preparation method thereof Pending CN107496267A (en)

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Cited By (3)

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CN109010188A (en) * 2018-10-08 2018-12-18 杭州三叶青农业科技有限公司 A kind of Lemna paucicostata is in the application for preparing clear acne and preserving youthful looks in gel
CN109330972A (en) * 2018-12-10 2019-02-15 孙笑笑 A kind of preparation method for subtracting age product of maintenance cell
CN109431942A (en) * 2018-12-22 2019-03-08 上海百年吴越化妆品有限公司 A kind of acne-eliminating cosmetic Chinese medicine composition and preparation method thereof

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CN105833187A (en) * 2016-05-14 2016-08-10 广东轻工职业技术学院 Botanical medicine composition with acne removing effect and application
CN106580822A (en) * 2016-12-16 2017-04-26 华南协同创新研究院 Plant acne-removing compound as well as preparation method and applications thereof
CN106727026A (en) * 2017-01-16 2017-05-31 四川新绿色药业科技发展有限公司 A kind of Chinese medicine acne-removing composition and its application

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109010188A (en) * 2018-10-08 2018-12-18 杭州三叶青农业科技有限公司 A kind of Lemna paucicostata is in the application for preparing clear acne and preserving youthful looks in gel
CN109330972A (en) * 2018-12-10 2019-02-15 孙笑笑 A kind of preparation method for subtracting age product of maintenance cell
CN109431942A (en) * 2018-12-22 2019-03-08 上海百年吴越化妆品有限公司 A kind of acne-eliminating cosmetic Chinese medicine composition and preparation method thereof

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Application publication date: 20171222