CN108542934A - A kind of external Chinese medicinal liniment and preparation method thereof of prevention acne-prone skin disease - Google Patents
A kind of external Chinese medicinal liniment and preparation method thereof of prevention acne-prone skin disease Download PDFInfo
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Abstract
The invention discloses a kind of external Chinese medicinal liniments and preparation method thereof of prevention acne-prone skin disease.The external Chinese medicinal liniment includes the raw material of following parts by weight：15 parts of sweet wormwood, 15 parts of kuh-seng, wild 15 parts of embankment, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of radix scutellariae, 15 parts of hymsleya amabilis, 15 parts of Radix Glycyrrhizae, 0.5 1 parts of borneol.The external Chinese medicinal liniment of the prevention acne-prone skin disease of the present invention and the composition of prescription requirement by Chinese medicine, with monarch, minister, assistant, make carry out prescription, final choice sweet wormwood, kuh-seng, wild embankment, the bulk pharmaceutical chemicals of Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae, 8 herbal medicine of borneol as prevention acne, curative effect height, for drug without influencing each other, toxic side effect is small；The present invention, with the pharmacological effect prescription of Chinese medicine, reduces medication from formula, cost-effective；Present invention process is reasonable, and effective ingredient extraction is more complete, does not have to add any preservative, and the stability of drug is strong, and drug effect is high.
Description
Technical field
The present invention relates to biomedicine technical field, it is specifically a kind of prevention acne-prone skin disease external Chinese medicinal liniment and its
Preparation method.
Background technology
Acne are commonly called as whelk, dark sore, modern medicine and claim acne, Chinese medicine ancient times that face sore, acne is claimed to be that dept. of dermatology is common
Disease, frequently-occurring disease.Acne are a kind of multifactor property diseases, and pathogenesis is not yet fully apparent from present.Endocrine factors, sebum
Microorganism is the principal element of acne morbidity in effect, hair follicle.It is counted according to scholars, has 95%, Nv Xingyou in Adolescent male
85% suffered from different degrees of acne.Acne are the chronic inflammations of a kind of hair follicle, sebaceous glands, are apt to occur in face, chest and back, can shape
At damages such as blackhead, papule, warts, tubercle, tumours.
Modern medicine finds four groups of microorganisms present in sebum hair follicle（Demodex folliculorum worm, bacillus acnes, white
Staphylococcus, oval pityriasis bud embrace bacterium）Though it can reduce fat, with the characteristics of bacillus acnes and demodex folliculorum,
Free fatty is just reduced when only such bacterium is reduced.Although bacillus acnes are in the free fatty of epidermis lipid generates
It plays a major role, but is not unique reason, mainly demodex folliculorum parasitism causes, and follicular wall lesion ruptures is caused to hinder
Plug, sebum row rush down obstacle and cause acne.Then cause infection, cause the free fatty in keratinocyte, sebum and sebum with
And bacillus acnes etc. enter in corium, so as to cause the different degrees of deep inflammation tubercle of perifollicolar.
In terms for the treatment of, Western medicine is mostly used steroids such as diethylstilbestrol, antibiotic such as Fourth Ring medicine class and vitamin B complex, this kind of to control
Treatment method can only control table, and unsuitable long term usage, because of endocrine and physiologic factor, rear easily recurrence.Local treatment is mostly used creme and is applied to
The cosmetics youth frost of acne and its fossil pigments is eliminated in affected part as disclosed in GN1137890A95106278.6, it is by field
Bamboo grass extract liquor, vitamin C, pearl powder, metronidazole, glycerine and other cosmetic additive agents are processed into cream, and this kind of product is to Cuo
Sore and its fossil pigments have certain therapeutic effect, but have certain irritation to skin, and hinder skin after ointment preparation smearing
Eubolism.
Also occurs the Chinese medicine of many prevention acne dermatosis now, State Intellectual Property Office is in public affairs on April 20th, 2011
A Publication No. CN102018937A has been opened, application No. is 201010585918.9, a kind of entitled " drug for treating acne
And preparation method " patent of invention, the invention discloses a kind of drug for treating acne, raw materials used and mass fraction is：In vain
The root of Dahurian angelica, kuh-seng, radix scutellariae, Cortex Phellodendri, rheum officinale, honeysuckle, wild chrysanthemum, aloe, cape jasmine, peppermint, turmeric, Poria cocos are 50-70 parts each, courage south
Star, dried orange peel, rhizoma atractylodis, Cortex Magnoliae Officinalis, Radix Glycyrrhizae, root of Chinese trichosanthes, pueraria lobata, radix polygonati officinalis are 30-50 parts each, each 6 parts of pearl powder, sulphur, borneol.The drug
It can be used for treating the scar left after acne, acne and its acne.It belongs to pure Chinese medicinal preparation, has no toxic side effect, at low cost
It is honest and clean.
For another example State Intellectual Property Office disclosed a Publication No. CN102114216A, application number on July 6th, 2011
It is 201010571732.8, entitled " a kind of to be applied with antibacterial anti-inflammatory medicament and preparation method thereof " patent of invention, present invention public affairs
A kind of external application antibacterial anti-inflammatory medicament and preparation method thereof has been opened, has been related to antiphlogistic medicament and preparation method thereof, by raw material peppermint, chaste tree
Mustard, windproof, rheum officinale, Cortex Phellodendri, Herba Andrographitis, Fructus Forsythiae, radix scutellariae, bavin flower Chinese violet, Radix Salviae Miltiorrhizae, kuh-seng, the root of Dahurain angelica, moutan bark, aloe, Radix Astragali,
Folium isatidis, sweet wormwood, felwort, Asian puccoon, Radix Glycyrrhizae, Chinese gall, the coptis, cassia seed, Radix Isatidis, honeysuckle, chrysanthemum, hawthorn, the tuber of stemona,
Folium artemisiae argyi, frutus cnidii, borneol powder, borax powder, honey, glycerine, propylene glycol, polysorbate60, OP10, castor oil, turpentine oil processing system
At.This product antibacterial and anti-inflammatory effects are good, and bacterium not will produce antibody, avoid bacterial dissociation at superbacteria, have no toxic side effect, make
With safety.
But the Chinese medicine preparation in above-mentioned two patent documents still remains following disadvantage：The formulation principle of Chinese medicine is not pressed：
Fang Congfa goes out, with monarch, composition of prescription minister, helped, made, and formula prodrug complex, function is indefinite, and curative effect is not high, and drug has phase
It mutually influences, increases toxic side effect；Chinese medicinal preparation method in above-mentioned patent is simple for process, is not carried by the selection of the effective ingredient of Chinese medicine
Take solution, direct external application after crushing, so there are problems that effective ingredient extraction it is incomplete the defects of and.Therefore, the present invention provides
A kind of external Chinese medicinal liniment and preparation method thereof of prevention acne-prone skin disease.
Invention content
The purpose of the present invention is to provide a kind of external Chinese medicinal liniments and preparation method thereof of prevention acne-prone skin disease, with solution
Certainly the problems mentioned above in the background art.
To achieve the above object, the present invention provides the following technical solutions：
A kind of external Chinese medicinal liniment of prevention acne-prone skin disease, includes the raw material of following parts by weight：1-5 parts of sweet wormwood, kuh-seng 1-5
Part, wild 1-5 parts of embankment, 1-5 parts of Radix Salviae Miltiorrhizae, 1-5 parts of radix scutellariae, 1-5 parts of hymsleya amabilis, 1-5 parts of Radix Glycyrrhizae, 0.5-1 parts of borneol.
As further scheme of the invention：Include the raw material of following parts by weight：1 part of sweet wormwood, 1 part of kuh-seng, wild dam
1 part of son, 1 part of Radix Salviae Miltiorrhizae, 1 part of radix scutellariae, 1 part of hymsleya amabilis, 1 part of Radix Glycyrrhizae, 0.5 part of borneol.
As further scheme of the invention：Include the raw material of following parts by weight：5 parts of sweet wormwood, 5 parts of kuh-seng, wild dam
5 parts of son, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of radix scutellariae, 5 parts of hymsleya amabilis, 5 parts of Radix Glycyrrhizae, 1 part of borneol.
A kind of preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease, includes the following steps：
A, 1-5 parts of sweet wormwood, 1-5 parts of kuh-seng, wild 1-5 parts of embankment, 1-5 parts of Radix Salviae Miltiorrhizae, 1-5 parts of radix scutellariae, 1-5 parts of hymsleya amabilis, Radix Glycyrrhizae are weighed
1-5 parts, 0.5-1 parts of borneol, it is spare；
B, and then by sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol 20-40 mesh powders are respectively crushed into；
C, water-alcohol solution is prepared：40-50 parts of the ethanol solution that mass fraction is 95%, 40-60 parts of softened water are taken, water alcohol is configured to
Solution, then with boron acid for adjusting pH value to 5.5-6.5；
D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux cycle extraction at normal temperatures,
Dipping reflux cycle extraction 0.5-2h is carried out every time, carries out dipping reflux cycle extraction 0.5-2h, repeated impregnations after standing for 24 hours again
Reflux cycle is extracted 4-7 time, is stood, is filtered, filtrate is filling gets product.
As further scheme of the invention：In step D, dipping reflux cycle is extracted as Soakage extraction method and reflux carries
It follows the example of alternate cycles and uses the method extracted to drug.
As further scheme of the invention：The preparation method of the softened water is：Drinking water is put into and is heated to
It 90-92 DEG C, is kept for 3-5 minutes, then cools down, filters to obtain the final product.
Compared with prior art, the beneficial effects of the invention are as follows：
The external Chinese medicinal liniment of the prevention acne-prone skin disease of the present invention debates disease according to Chinese medicine and treats the original being combined with dialectical treatmert
Then, and by the composition of prescription requirement of Chinese medicine, with monarch, minister, assistant makes carry out prescription, final choice sweet wormwood, kuh-seng, wild embankment, pellet
The bulk pharmaceutical chemicals of ginseng, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae, 8 herbal medicine of borneol as prevention acne, curative effect is high, and drug is without influencing each other, poison
Small side effects；The present invention, with the pharmacological effect prescription of Chinese medicine, reduces medication from formula, cost-effective；Present invention process is reasonable,
Effective ingredient extraction is more complete, does not have to add any preservative, and the stability of drug is strong, and drug effect is high.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Embodiment 1
A kind of external Chinese medicinal liniment of prevention acne-prone skin disease, includes the raw material of following parts by weight：1 part of sweet wormwood, 1 part of kuh-seng,
1 part of wild embankment, 1 part of Radix Salviae Miltiorrhizae, 1 part of radix scutellariae, 1 part of hymsleya amabilis, 1 part of Radix Glycyrrhizae, 0.5 part of borneol.
A kind of preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease, includes the following steps：A, sweet wormwood 1 is weighed
Part, 1 part of kuh-seng, wild 1 part of embankment, 1 part of Radix Salviae Miltiorrhizae, 1 part of radix scutellariae, 1 part of hymsleya amabilis, 1 part of Radix Glycyrrhizae, 0.5 part of borneol, it is spare；It B, and then will
Sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol are respectively crushed into 20 mesh powders；C, water-alcohol solution is prepared：
40 parts of the ethanol solution that mass fraction is 95%, 60 parts of softened water are taken, is configured to water-alcohol solution, then extremely with boron acid for adjusting pH value
5.5；D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux cycle extraction at normal temperatures,
Dipping reflux cycle extraction 0.5h is carried out every time, carries out dipping reflux cycle extraction 0.5h, repeated impregnations reflux after standing for 24 hours again
Cycle extraction 4 times is stood, filtering, filtrate is filling gets product.In step D, dipping reflux cycle be extracted as Soakage extraction method and
Reflux extraction alternate cycles use the method extracted to drug；Single impregnation is extracted or the time of refluxing extraction is unlimited,
It keeps carrying out dipping reflux cycle extraction 0.5h every time.The preparation method of the softened water is：Using GB5749《Life
Drinking water》, drinking water containing multi mineral ingredient, drinking water is put into and is heated to 90 DEG C, is kept for 3 minutes, then cooling, mistake
It filters to obtain the final product；The softened water eliminates calcium ions and magnesium ions and macromolecular colloid substance in water, and water molecule group is small, good penetrability, have compared with
It is strongly active.
The application method of the external Chinese medicinal liniment is：In use, being stained with liquid with cotton swab embrocates affected part or liquid soak in powder
It is 2-3 times daily at thorn, 15 days as one therapeutic course.
Embodiment 2
A kind of external Chinese medicinal liniment of prevention acne-prone skin disease, includes the raw material of following parts by weight：5 parts of sweet wormwood, 5 parts of kuh-seng,
5 parts of wild embankment, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of radix scutellariae, 5 parts of hymsleya amabilis, 5 parts of Radix Glycyrrhizae, 1 part of borneol.
A kind of preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease, includes the following steps：A, sweet wormwood 5 is weighed
Part, 5 parts of kuh-seng, wild 5 parts of embankment, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of radix scutellariae, 5 parts of hymsleya amabilis, 5 parts of Radix Glycyrrhizae, 1 part of borneol, it is spare；It B, and then will be green
Wormwood artemisia, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol are respectively crushed into 40 mesh powders；C, water-alcohol solution is prepared：It takes
50 parts of ethanol solution that mass fraction is 95%, 40 parts of softened water, are configured to water-alcohol solution, then with boron acid for adjusting pH value to 6.5；
D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux cycle extraction at normal temperatures, every time
Dipping reflux cycle extraction 2h is carried out, carries out dipping reflux cycle extraction 2h, the extraction of repeated impregnations reflux cycle after standing for 24 hours again
It 7 times, stands, filtering, filtrate is filling gets product.In step D, dipping reflux cycle is extracted as Soakage extraction method and refluxing extraction
Method alternate cycles use the method extracted to drug；Single impregnation is extracted or the time of refluxing extraction is unlimited, keeps each
Carry out dipping reflux cycle extraction 2h.The preparation method of the softened water is：Using GB5749《Drinking Water》, contain
There are many drinking water of mineralogical composition, drinking water is put into and is heated to 92 DEG C, kept for 5 minutes, then cool down, filter to obtain the final product；It should
Softened water eliminates calcium ions and magnesium ions and macromolecular colloid substance in water, and water molecule group is small, good penetrability, has more strongly active.
The application method of the external Chinese medicinal liniment is：In use, being stained with liquid with cotton swab embrocates affected part or liquid soak in powder
It is 2-3 times daily at thorn, 15 days as one therapeutic course.
Embodiment 3
A kind of external Chinese medicinal liniment of prevention acne-prone skin disease, includes the raw material of following parts by weight：3.5 parts of sweet wormwood, kuh-seng 3.5
Part, wild 3.5 parts of embankment, 3.5 parts of Radix Salviae Miltiorrhizae, 3.5 parts of radix scutellariae, 3.5 parts of hymsleya amabilis, 3.5 parts of Radix Glycyrrhizae, 0.75 part of borneol.
A kind of preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease, includes the following steps：A, sweet wormwood 3.5 is weighed
Part, 3.5 parts of kuh-seng, wild 3.5 parts of embankment, 3.5 parts of Radix Salviae Miltiorrhizae, 3.5 parts of radix scutellariae, 3.5 parts of hymsleya amabilis, 3.5 parts of Radix Glycyrrhizae, 0.75 part of borneol,
It is spare；B, and then by sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol 30 mesh powders are respectively crushed into；C、
Prepare water-alcohol solution：45 parts of the ethanol solution that mass fraction is 95%, 45 parts of softened water are taken, is configured to water-alcohol solution, then use boric acid
PH value is adjusted to 6；D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux at normal temperatures follows
Ring extracts, and carries out dipping reflux cycle extraction 1.5h every time, carries out dipping reflux cycle extraction 1.5h after standing for 24 hours again, repeats
It impregnates reflux cycle to extract 6 times, stand, filtering, filtrate is filling gets product.In step D, dipping reflux cycle is extracted as impregnating
Extraction method and reflux extraction alternate cycles use the method extracted to drug；Single impregnation extract or refluxing extraction when
Between it is unlimited, keep every time carries out dipping reflux cycle extraction 1.5h.The preparation method of the softened water is：Using
GB5749《Drinking Water》, drinking water containing multi mineral ingredient, drinking water is put into and is heated to 91 DEG C, is kept for 4 minutes,
Then it cools down, filter to obtain the final product；The softened water eliminates calcium ions and magnesium ions and macromolecular colloid substance in water, and water molecule group is small, oozes
Permeability is good, has more strongly active.
The application method of the external Chinese medicinal liniment is：In use, being stained with liquid with cotton swab embrocates affected part or liquid soak in powder
It is 2-3 times daily at thorn, 15 days as one therapeutic course.
Embodiment 4
A kind of external Chinese medicinal liniment of prevention acne-prone skin disease, includes the raw material of following parts by weight：2 parts of sweet wormwood, 2 parts of kuh-seng,
2 parts of wild embankment, 2 parts of Radix Salviae Miltiorrhizae, 2 parts of radix scutellariae, 2 parts of hymsleya amabilis, 2 parts of Radix Glycyrrhizae, 0.5 part of borneol.
A kind of preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease, includes the following steps：A, sweet wormwood 2 is weighed
Part, 2 parts of kuh-seng, wild 2 parts of embankment, 2 parts of Radix Salviae Miltiorrhizae, 2 parts of radix scutellariae, 2 parts of hymsleya amabilis, 2 parts of Radix Glycyrrhizae, 0.5 part of borneol, it is spare；It B, and then will
Sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol are respectively crushed into 30 mesh powders；C, water-alcohol solution is prepared：
45 parts of the ethanol solution that mass fraction is 95%, 50 parts of softened water are taken, is configured to water-alcohol solution, then extremely with boron acid for adjusting pH value
5.5；D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux cycle extraction at normal temperatures,
Dipping reflux cycle extraction 1h is carried out every time, carries out dipping reflux cycle extraction 1h, repeated impregnations reflux cycle after standing for 24 hours again
Extraction 7 times is stood, filtering, filtrate is filling gets product.In step D, dipping reflux cycle is extracted as Soakage extraction method and reflux
Extraction method alternate cycles use the method extracted to drug；Single impregnation is extracted or the time of refluxing extraction is unlimited, is kept
Dipping reflux cycle extraction 1h is carried out every time.The preparation method of the softened water is：Using GB5749《Life is drunk
Water》, drinking water containing multi mineral ingredient, drinking water is put into and is heated to 91 DEG C, is kept for 5 minutes, it is then cooling, filter and be
；The softened water eliminates calcium ions and magnesium ions and macromolecular colloid substance in water, and water molecule group is small, good penetrability, there is stronger work
Property.
The application method of the external Chinese medicinal liniment is：In use, being stained with liquid with cotton swab embrocates affected part or liquid soak in powder
It is 2-3 times daily at thorn, 15 days as one therapeutic course.
It in clinical application, is verified through the outpatient service of dermatopathy and venereal disease study on prevention institute of Sichuan Province, from October, 2012 to 2013
87 various acne of year outpatient service in October Randomized treatment, obvious effective rate 68.56%, gross efficiency 98.66%.Have according to clinical verification really
Curative effect is cut, especially preferable to the cutaneous inflammatory lesion of acne, such as papule, shallow dense blister and epifolliculitis effect, general medication starts to see for 3-4 days
Effect, starts to subside for one week or so, has certain effect to improving skin greasing, and have fat of dispelling, skin care, mitigate pigmentation, is pre-
The effect of anti-acne.
The present invention is detected through Food In Sichuan Province drug inspection center with regard to lead, arsenic, mercury, methanol, bacterium, fecal coliform, golden yellow
The projects such as color staphylococcus, green pus coccus and Skin Irritation Test are detected, and result meets《GB7916-87》Standard.
The present invention operation principle be：The preparation method of the present invention utilizes water alcohol method and infusion process principle, selects hydrophilic, close
The strong water-alcohol solution of lipid, the method carried out using infusion process and circumfluence method cycle alternation, comprehensive extraction effective ingredient are overcome
Traditional Chinese medicine is single using decoction, aqua, simple organic solvent extraction effective components of Chinese medicinal, and extraction composition is incomplete, and dosage form is not
Stablize, toxic side effect, it is inconvenient to use the shortcomings of.The present invention is carried out to traditional handicraft in existing extraction traditional Chinese medicine technology
It improves, the big compound of traditional Chinese medicine is overcome with the pharmacological effect prescription of Chinese medicine from formula, reduce medication, it is cost-effective etc..This
Invention does not have to add any preservative, enhances the stability of drug, improves drug effect.
The theoretical foundation of the present invention：Disease, which is debated, according to Chinese medicine treats the principle being combined with dialectical treatmert, and matching by Chinese medicine
The requirement of 5 prescriptions, with monarch, minister, assistant makes carry out prescription, selects sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae, ice
8 herbal medicine of piece by experimental formula repeatedly, bulk pharmaceutical chemicals of the final choice said medicine as prevention acne, and determines monarch drug in a prescription,
Ministerial drug, adjutant make the proportioning of medicine.Sweet wormwood wherein in monarch drug in a prescription sweet wormwood is known as resisting pathogenic microbes effect, and sweet wormwood water decoction is to more
Kind bacterium has inhibiting effect, volatile oil to have killing effect to skin tinea.Monarch drug in a prescription kuh-seng, the matrine and active material of extraction have aobvious
It writes and extensive antibacterial anti-inflammatory and killing acarid effect, and also has inhibiting effect to a variety of dermatophytes.Monarch drug in a prescription open country embankment has
The effect of clearing heat and detoxicating, hemostasis and pain-relieving, the diseases such as traumatic hemorrhage, rotten sore, mosquito bite wound.Ministerial drug Radix Salviae Miltiorrhizae, antibacterial and anti-inflammation functions are in vitro
It is found in antibacterial tests, the extract total-tanshinone of Radix Salviae Miltiorrhizae has stronger antibacterial work to staphylococcus aureus and its antibody-resistant bacterium
With, and have inhibiting effect to staphylococcus, Escherichia coli, denaturation bacillus.Ministerial drug radix scutellariae, antibacterial, antivirus action, to a variety of leather
Blue positive bacteria, gram-negative bacteria, pathogenic dermatophyte have inhibiting effect；It is antiviral, inhibit influenza virus；Anti-inflammatory, radix scutellariae carries
It takes object to have inhibition acute inflammatory reaction, inflammatory seep swelling, capillary permeability is inhibited to increase, inflammatory mediator generation is inhibited to release
It puts；Inhibit histamine release to mitigate inflammatory mediator and expand blood vessel, increases Vascular Permeability, the chemotaxis of leucocyte；Antibacterial is made
With better than the coptis, do not develop immunity to drugs.Ministerial drug hymsleya amabilis, lovely hemsleya extract have broad spectrum of bacteria antiinflammation, inhibit anaerobic bacteria, hair follicle compacted
Shape acarid, clearing heat and detoxicating, fat scale removal of dispelling, Hemsleyadin and hemsloside are in vitro to shigella flexneri, typhoid bacillus, hog cholera
Salmonella etc. has different degrees of inhibiting effect；It is clinically used to treat bacillary dysentery, chordapsus and inflammation is waited to receive
To preferable effect.Adjutant borneol leads to all keys, dissipates stagnated fire, goes screen improving eyesight, swelling and pain relieving, the diseases such as carbuncle swells.Make medicine Radix Glycyrrhizae, is to draw
Through medicine, harmonizing drug is clearing heat and detoxicating, effects of antiinflammation and bacteriostasis.The combination of said medicine and formula are to debate disease according to Chinese medicine to treat and debate
Card opinion controls the principle being combined, and presses the composition of prescription requirement of Chinese medicine, and with monarch, minister helps, makes carry out prescription, for causing acne
The principal element of morbidity（Endocrine factors, the effect of sebum, the factors such as microorganism in hair follicle）To select the above drug, prescription section
It learns, the drug effect of each raw material can be given full play to, reach best prevention acne effect.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party
Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective
Various changes can be made.
Claims (6)
1. a kind of external Chinese medicinal liniment of prevention acne-prone skin disease, which is characterized in that include the raw material of following parts by weight：Sweet wormwood
1-5 parts, 1-5 parts of kuh-seng, wild 1-5 parts of embankment, 1-5 parts of Radix Salviae Miltiorrhizae, 1-5 parts of radix scutellariae, 1-5 parts of hymsleya amabilis, 1-5 parts of Radix Glycyrrhizae, borneol 0.5-1
Part.
2. the external Chinese medicinal liniment of prevention acne-prone skin disease according to claim 1, which is characterized in that including following weight
The raw material of number：1 part of sweet wormwood, 1 part of kuh-seng, wild 1 part of embankment, 1 part of Radix Salviae Miltiorrhizae, 1 part of radix scutellariae, 1 part of hymsleya amabilis, 1 part of Radix Glycyrrhizae, borneol 0.5
Part.
3. the external Chinese medicinal liniment of prevention acne-prone skin disease according to claim 1, which is characterized in that including following weight
The raw material of number：5 parts of sweet wormwood, 5 parts of kuh-seng, wild 5 parts of embankment, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of radix scutellariae, 5 parts of hymsleya amabilis, 5 parts of Radix Glycyrrhizae, 1 part of borneol.
4. a kind of preparation method of external Chinese medicinal liniment according to any prevention acne-prone skin diseases of claim 1-3,
It is characterized in that, includes the following steps：
A, 1-5 parts of sweet wormwood, 1-5 parts of kuh-seng, wild 1-5 parts of embankment, 1-5 parts of Radix Salviae Miltiorrhizae, 1-5 parts of radix scutellariae, 1-5 parts of hymsleya amabilis, Radix Glycyrrhizae are weighed
1-5 parts, 0.5-1 parts of borneol, it is spare；
B, and then by sweet wormwood, kuh-seng, wild embankment, Radix Salviae Miltiorrhizae, radix scutellariae, hymsleya amabilis, Radix Glycyrrhizae and borneol 20-40 mesh powders are respectively crushed into；
C, water-alcohol solution is prepared：40-50 parts of the ethanol solution that mass fraction is 95%, 40-60 parts of softened water are taken, water alcohol is configured to
Solution, then with boron acid for adjusting pH value to 5.5-6.5；
D, the powder for obtaining step B is added in water-alcohol solution, stirs evenly；Then dipping reflux cycle extraction at normal temperatures,
Dipping reflux cycle extraction 0.5-2h is carried out every time, carries out dipping reflux cycle extraction 0.5-2h, repeated impregnations after standing for 24 hours again
Reflux cycle is extracted 4-7 time, is stood, is filtered, filtrate is filling gets product.
5. the preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease according to claim 4, which is characterized in that step
In rapid D, dipping reflux cycle is extracted as Soakage extraction method and reflux extraction alternate cycles use the side extracted to drug
Method.
6. the preparation method of the external Chinese medicinal liniment of prevention acne-prone skin disease according to claim 4, which is characterized in that institute
The preparation method for the softened water stated is：Drinking water is put into and is heated to 90-92 DEG C, is kept for 3-5 minutes, then cooling, filtering is
.
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