CN106727011A - A kind of anti-acne lotion - Google Patents
A kind of anti-acne lotion Download PDFInfo
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- CN106727011A CN106727011A CN201710007063.3A CN201710007063A CN106727011A CN 106727011 A CN106727011 A CN 106727011A CN 201710007063 A CN201710007063 A CN 201710007063A CN 106727011 A CN106727011 A CN 106727011A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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Abstract
The invention discloses a kind of acne removing water, mainly by Fructus Anisi Stellati extract, Honegsukle flower P.E, oranges and tangerines bark extract, 1,3 propane diols part, Sodium Hyaluronate part, 1,2 pentanediols, borneol, Phenoxyethanol etc. into being grouped into.Acne removing water of the present invention has compounded borneol and 1,3 propane diols, the infiltration its object is to promote product；Transparent Sodium Hyaluronate and 1 are compounded, 2 pentanediols are good NMFs, there is powerful water lock to absorb water effect；The suppression that Fructus Anisi Stellati extract is conducive to harmful bacteria is compounded；Compounding Honegsukle flower P.E is clearing heat and detoxicating, inhibiting bacteria and diminishing inflammation；Compounding oranges and tangerines bark extract safeguards skin micro-ecological environment, has anti-inflammatory and trophism concurrently.Various raw material science compoundings, Synergistic realizes good anti-acne effect, while.Promote skin metabolism, effectively repair and damage skin.Acne removing water of the invention is naturally gentle, safely and effectively, preparation process is simple, low production cost, the characteristics of impart product economy material benefit.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of anti-acne lotion.
Background technology
Acne is one of most common skin problem, is shown according to epidemiology survey, west 80% teenager and
50% adult has different degrees of acne, and almost 95% Chinese face is long has " whelk ", and 55% people
Long-term acne long.Acne is a kind of infective inflammation of pilosebaceous follicle.Follicular orifice is opened on sebaceous glands more, once follicular orifice hinders
Plug, the propionibacterium acnes of hyper-proliferative in the stimulation of the excess fat acid that excessive sebum metabolism is produced and enclosed environment
Effect, skin is generated inflammatory reaction, the lipase that propionibacterium acnes is produced decomposes sebum generation free fatty, while
Chemotactic inflammatory cell and medium, finally induce and aggravate inflammatory reaction.Therefore the performance of small pox is from gently to being again hoary hair's blackhead powder
Thorn, inflamed papules and warts, tumour and tubercle, and rubescent and suppuration small pox is with the presence of bacterium infection.Whelk is serious
Influence the appearance and confidence of people, work to people, life produce negative influence, thus acne-eliminating cosmetic be research focus it
One.
Chinese patent application CN102028648A discloses the preparation method of a kind of acne removing water and its active ingredient, the anti-acne
Water is made up of the water of 10-50 parts of Flos Chrysanthemi Indici extract and 100-200 part.The comparison of ingredients of the invention is single, and product is only absorbed in
On antibacterial, the cell to being damaged does not have repair.
Product for resolving poxes at present on the market for whelk is relatively more, but essentially anti-virus activities bactericide, and some even make
It is instant effect the characteristics of this kind of product with antibiotic such as chloramphenicol, clindamycins, easily repeatedly, easily produces dependence；Laser is controlled
The method for the treatment of is rapid-action, but can not provide the irradiation light for destroying propionic acid whelk bacillus completely；Glucocorticoid treatment meeting
Producing immunosuppressive action, excessive use can produce secondary recurrence；It is people using the medicine adornment of the natural component containing acne-removing
Pursue gentle effective anti-acne method, be also one of emphasis of research and development.
The content of the invention
It is an object of the invention to provide a kind of gentle effective anti-acne lotion.
Containing the anti-acne plant composition that weight portion is 0.7-2.5 parts in a kind of anti-acne lotion that the present invention is provided, its
Described in acne-removing composition be Fructus Anisi Stellati extract, Honegsukle flower P.E, the mixture of oranges and tangerines bark extract.
Preferably, in a kind of described anti-acne lotion, the anti-acne plant composition is by following weight portion into packet
Into：Fructus Anisi Stellati extract 0.2-0.8 parts, Honegsukle flower P.E 0.3-0.8 parts, 0.2-0.9 parts of oranges and tangerines bark extract.
Preferably, in a kind of described anti-acne lotion, the Fructus Anisi Stellati extract is prepared by the following method：
(1) take a Chinese anise and be crushed to 30-50 mesh, add 6 times of amount deionized waters to decoct 30-60min, be repeated 3 times,
Collecting decoction, filtering, normal pressure is concentrated into pasty state；
(2) step (1) pastel is taken, plus 4 times of 90% ethanol of amount stir, and 1% sodium hydroxide solution regulation pH is added dropwise
It is closed to stand overnight to 8；
(3) step (2) feed liquid is taken, depressurize suction filtration, filtrate recycling ethanol is to without alcohol taste, 0-4 DEG C of refrigeration 24h；
(4) by step (3) feed liquid filtration under diminished pressure, the concentration of filtrate normal pressure obtains Fructus Anisi Stellati extract.
Preferably, in a kind of described anti-acne lotion, the Honegsukle flower P.E is prepared by the following method：
(1) steeping tank is added after taking a honeysuckle grinding, 75% ethanol solution is added, solid-liquid ratio is 1:30, stirring leaching
Bubble 15-20h；
(2) being transferred to the feed liquid in step (1) carries out microwave abstracting in extractor, extraction time is 15-40 minutes, is extracted
Temperature is 50-100 DEG C, and microwave power is 300-1500W；Extract filtering is obtained final product into Honegsukle flower P.E.
Preferably, in a kind of described anti-acne lotion, the oranges and tangerines bark extract is prepared by the following method：
(1) pretreatment of raw material：Citrus peel meal is broken to 10-20 mesh, 40 DEG C of dry for standby；
(2) infusion process refluxing extraction：The ethanol solution of 40% concentration is added, solid-liquid ratio is 1:Impregnated under the conditions of 16,60 DEG C
Method backflow leaching, 2-3h；
(3) it is concentrated under reduced pressure：Under the conditions of 50-65 DEG C, fluid density is concentrated into for 1.2g/ml；
(4) it is vacuum dried：Concentrate is vacuum dried under the conditions of 60-64 DEG C, oranges and tangerines bark extract is obtained.
Preferably, a kind of described anti-acne lotion, is composed of the following components in parts by weight：Anti-acne plant composition 0.7-
2.5 parts, EDETATE SODIUM 0.01-0.05 parts, 5-10 parts of 1,3- propane diols, Carbomer 0.2-0.5 parts, Sodium Hyaluronate 0.01-
0.05 part, allantoin 0.05-0.3 parts, 1-3 parts of 1,2- pentanediols, borneol 0.05-0.2 parts, Phenoxyethanol 0.2-0.8 parts, go from
Sub- water is to 100 parts.
Preferably, the preparation method of described a kind of anti-acne lotion, it is characterised in that the preparation method includes following
Step：
(1) accurately weigh EDETATE SODIUM, 1,3- propane diols, Carbomer, Sodium Hyaluronate, allantoin, 1,2- pentanediols and
Deionized water, adds agitated kettle to mix, and is heated to 80~85 DEG C, is uniformly dispersed；
(2) 40~45 DEG C are cooled to, borneol, anti-acne plant composition, Phenoxyethanol are sequentially added and is stirred.
Effect or feature of main component of the present invention are as follows：
In Fructus Anisi Stellati extract containing Luteolin, catechin, glucoside, vanillic acid, daucosterol, isoesdragol,
Anisic aldehyde, chavicol methyl ether etc..With antibacterial, insecticidal activity and Green Tea Extract oxidation.Chinese anise water decoction is to tuberculosis bar
Bacterium and hay bacillus have inhibitory action, and its ethanol extract is to staphylococcus aureus, pneumococcus, paratyphosum Bacterium, dysentery
Bacillus and some Common Pathogenic candida albicans have inhibitory action.
Honegsukle flower P.E contains various volatile oil and chlorogenic acid, various aglycon compositions, and substantial amounts of flavone compound
Deng.With clearing heat and detoxicating, broad-spectrum antiseptic, antiviral, antitumor, enhancing be immune and the effect such as antipyretic and anti-inflammatory, antiulcer.Once had perhaps
Many reports show that Honegsukle flower P.E synthesizes by suppressing drug-fast bacteria protein, in vitro to various pathogenic bacterias, there is difference
The inhibitory action of degree.
Orange peel extract flavone class, vitamin C, carotenoid, limonin, flavonoids, linalool, amino acid, egg
White matter etc..Hesperidine has citrin sample to act on, and can reduce capillary permeability, prevents microvascular bleeding, maintains skin ring
Border；The vasopermeability that can be caused with antagonizing histamine, lysolecithin increases, and plays anti-inflammatory anti-allergic effects；Meanwhile, also wind-dispelling
Cold, sleeping, the effects such as calm the nerves, remove peculiar smell.
Beneficial effects of the present invention：(1) Fructus Anisi Stellati extract is conducive to harmful bacteria in acne-removing composition of the invention
Suppress, it is anti-oxidant；Honegsukle flower P.E is clearing heat and detoxicating, inhibiting bacteria and diminishing inflammation；Oranges and tangerines bark extract safeguards skin micro-ecological environment, has concurrently
Anti-inflammatory and trophism, through experiment, several natural components are combined, with excellent anti-acne effect.Compounding borneol and 1,
Ammediol, can promote the active ingredient of acne-removing composition to penetrate into skin；Compounding Sodium Hyaluronate does well with 1,2- pentanediols
NMF, there is powerful water lock to absorb water effect, each component synergy realizes good anti-acne effect, meanwhile, promote skin
Skin is metabolized, and effectively repairs and damages skin, nutrition Glycerin；(2) anti-acne lotion preparation process is simple of the invention, is produced into
This is low, the characteristics of impart product economy material benefit；(3) present invention in active ingredient naturally safety, and 1,2- pentanediol with
Traditional preservatives Phenoxyethanol compounding also has synergistic function, and the antiseptic effect of enhanced products reduces the excitant of product, subtracts
The allergy that few preservative causes so that product is gentleer, safety.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
The embodiment of the present invention 1~3 and the anti-acne lotion formula of comparative example 1~3 are shown in Table one
Table one
The Fructus Anisi Stellati extract is prepared by the following method：
(1) take a Chinese anise and be crushed to 40 mesh, add 6 times of amount deionized waters to decoct 50min, be repeated 3 times, merge and decoct
Liquid, filtering, normal pressure is concentrated into pasty state；
(2) step (1) pastel is taken, plus 4 times of 90% ethanol of amount stir, and 1% sodium hydroxide solution regulation pH is added dropwise
It is closed to stand overnight to 8；
(3) step (2) feed liquid is taken, depressurize suction filtration, filtrate recycling ethanol is to without alcohol taste, 0-4 DEG C of refrigeration 24h；
(4) by step (3) feed liquid filtration under diminished pressure, the concentration of filtrate normal pressure obtains Fructus Anisi Stellati extract.
The Honegsukle flower P.E is prepared by the following method：
(1) steeping tank is added after taking a honeysuckle grinding, 75% ethanol solution is added, solid-liquid ratio is 1:30, stirring leaching
Bubble 17h；
(2) being transferred to the feed liquid in step (1) carries out microwave abstracting in extractor, extraction time is 20 minutes, extracts temperature
It is 100 DEG C to spend, and microwave power is 1500W；Extract filtering is obtained final product into Honegsukle flower P.E.
The oranges and tangerines bark extract is prepared by the following method：
(1) pretreatment of raw material：Citrus peel meal is broken to 15 mesh, 40 DEG C of dry for standby；
(2) infusion process refluxing extraction：The ethanol solution of 40% concentration is added, solid-liquid ratio is 1:Impregnated under the conditions of 16,60 DEG C
Method backflow leaching, 3h；
(3) it is concentrated under reduced pressure：Under the conditions of 65 DEG C, fluid density is concentrated into for 1.2g/ml；
(4) it is vacuum dried：Concentrate is vacuum dried under the conditions of 64 DEG C, oranges and tangerines bark extract is obtained.
The preparation method of embodiment 1~3 and the anti-acne lotion of comparative example 1~5 is comprised the following steps：
(1) accurately weigh EDETATE SODIUM, 1,3- propane diols, Carbomer, Sodium Hyaluronate, allantoin, 1,2- pentanediols and
Deionized water, adds agitated kettle to mix, and is heated to 80 DEG C, is uniformly dispersed；
(2) 45 DEG C are cooled to, borneol, anti-acne plant composition, Phenoxyethanol are sequentially added and is stirred discharging.
Efficacy validation
Choose homeliness type acne patient 180, male patient 88, female patient 92, the age (20 ± 1) year, the course of disease
(20.1 ± 18.4) individual month.All patient's voluntary participation clinical observations, sign Informed Consent Form, and use dispelling for providing on request
Acne lotion.
Selection standard:Glucocorticoid, dimension A classes medicine, antibiotic etc. are taken in clinical observation the last fortnight, and in the observation period
Between do not use said medicine；No drinking during observation, excessively pungent stimulation group food is not eaten.
180 people are randomly divided into 9 groups, every group of 20 people correspond to embodiment 1~3 respectively, and the comparative example 6 of comparative example 1~6 is certain
Commercially available anti-acne lotion.Patient daily sooner or later by Irrigation after clean after the appropriate face cleaning dew that will provide be evenly coated in it is right on the face
After clean up, continue more than 30d must not be interrupted.
Patient use preceding and use after the 10th, 20,30d respectively observation once, to extent according to level Four score into
Row scoring, while observing and recording adverse reaction, draws skin repair effect.
Respectively inquire that patient adapts to impression using the 10th after preceding and use, 20,30d in patient.
Degree is improved according to skin damaged, course for the treatment of index is calculated, curative effect is judged.Therapeutic index is (long-pending after integration-curative effect before curative effect
Point) × 100% is integrated before/curative effect.It is almost recovered：Therapeutic index ＞ 75%, effective (remarkable result)：Therapeutic index be 50~
75%, effectively：Therapeutic index is 20~50%, invalid：Therapeutic index ＜ 20%.
Embodiment 1~3, comparative example 1~3 are being used, patient does not occur adverse reaction, the trouble of correspondence embodiment 1~3
Person, it is tender that reaction effect represents that skin more adds water very well, and all patients complete experiment.
Repair result and see the table below two
Table two
Visible lotion of the present invention is contrasted when Chinese anise is extracted by the comparative example 4 of table two and comparative example 5 and embodiment 1~3
When thing parts by weight are less than 2 or more than 8, inhibiting bacteria and diminishing inflammation effect can not show a candle to be more than or equal to 2 when Fructus Anisi Stellati extract parts by weight
During less than or equal to 8；When Fructus Anisi Stellati extract parts by weight are less than or equal to 8 more than or equal to 2, its inhibiting bacteria and diminishing inflammation effect is substantially high
In certain commercially available mildy wash；The visible Chinese anise in lotion of the present invention is contrasted by comparative example 1~3 and embodiment 1~3 to extract
Thing, Honegsukle flower P.E and orange bark extract have the effect of Synergistic in anti-acne
It is comfortable on when representing and use using the patient of the mildy wash of embodiment 1~3, without pain, does not have peculiar smell, skin
More add water tender.
Understand that anti-acne lotion of the present invention has functions that to become apparent from more preferable inhibiting bacteria and diminishing inflammation, moisturizing and nothing by experimental result
It is comfortable when peculiar smell is used.
Above example only illustrates embodiment of the present invention, does not there is any formal limitation to the present invention；Appoint
What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents for disclosing or modifies, as equivalent
The Equivalent embodiments of change, according to the technology of the present invention essence, simply modification, equivalent variations and modification are carried out to the present invention, are belonged to
In the range of technical solution of the present invention.
Claims (7)
1. a kind of anti-acne lotion, it is characterised in that contain the anti-acne that weight portion is for 0.7-2.5 parts in described anti-acne lotion
Plant composition, wherein the acne-removing composition is Fructus Anisi Stellati extract, Honegsukle flower P.E, the mixing of oranges and tangerines bark extract
Thing.
2. a kind of anti-acne lotion according to claim 1, it is characterised in that the anti-acne plant composition is by following heavy
Amount part into being grouped into：
Fructus Anisi Stellati extract 0.2-0.8 parts
Honegsukle flower P.E 0.3-0.8 parts
0.2-0.9 parts of oranges and tangerines bark extract.
3. a kind of anti-acne lotion according to claim 1 and 2, it is characterised in that the Fructus Anisi Stellati extract passes through
It is prepared by following methods：
(1) take a Chinese anise and be crushed to 30-50 mesh, add 6 times of amount deionized waters to decoct 30-60min, be repeated 3 times, merge
Decocting liquid, filtering, normal pressure is concentrated into pasty state；
(2) step (1) pastel is taken, plus 4 times of 90% ethanol of amount stir, and 1% sodium hydroxide solution is added dropwise and adjusts pH to 8,
It is closed to stand overnight；
(3) step (2) feed liquid is taken, depressurize suction filtration, filtrate recycling ethanol is to without alcohol taste, 0-4 DEG C of refrigeration 24h；
(4) by step (3) feed liquid filtration under diminished pressure, the concentration of filtrate normal pressure obtains Fructus Anisi Stellati extract.
4. a kind of anti-acne lotion according to claim 1 and 2, it is characterised in that the Honegsukle flower P.E by with
It is prepared by lower section method：
(1) steeping tank is added after taking a honeysuckle grinding, 75% ethanol solution is added, solid-liquid ratio is 1:30, stirring immersion 15-
20h；
(2) being transferred to the feed liquid in step (1) carries out microwave abstracting in extractor, extraction time is 15-40 minutes, Extracting temperature
It it is 50-100 DEG C, microwave power is 300-1500W；Extract filtering is obtained final product into Honegsukle flower P.E.
5. a kind of anti-acne lotion according to claim 1 and 2, it is characterised in that the oranges and tangerines bark extract by with
It is prepared by lower section method：
(1) pretreatment of raw material：Citrus peel meal is broken to 10-20 mesh, 40 DEG C of dry for standby；
(2) infusion process refluxing extraction：The ethanol solution of 40% concentration is added, solid-liquid ratio is 1:Infusion process is returned under the conditions of 16,60 DEG C
Stream leaching, 2-3h；
(3) it is concentrated under reduced pressure：Under the conditions of 50-65 DEG C, fluid density is concentrated into for 1.2g/ml；
(4) it is vacuum dried：Concentrate is vacuum dried under the conditions of 60-64 DEG C, oranges and tangerines bark extract is obtained.
6. a kind of anti-acne lotion, it is characterised in that the anti-acne lotion is composed of the following components in parts by weight：
0.7-2.5 parts of anti-acne plant composition
EDETATE SODIUM 0.01-0.05 parts
5-10 parts of 1,3- propane diols
Carbomer 0.2-0.5 parts
Sodium Hyaluronate 0.01-0.05 parts
Allantoin 0.05-0.3 parts
1-3 parts of 1,2- pentanediols
Borneol 0.05-0.2 parts
Phenoxyethanol 0.2-0.8 parts
Deionized water is to 100 parts.
7. a kind of preparation method of anti-acne lotion as claimed in claim 6, it is characterised in that the preparation method include with
Lower step：
(1) accurately weigh EDETATE SODIUM, 1,3- propane diols, Carbomer, Sodium Hyaluronate, allantoin, 1,2- pentanediols and go from
Sub- water, adds agitated kettle to mix, and is heated to 80~85 DEG C, is uniformly dispersed；
(2) 40~45 DEG C are cooled to, borneol, anti-acne plant composition, Phenoxyethanol are sequentially added and is stirred discharging.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106511189A (en) * | 2017-01-06 | 2017-03-22 | 广州聚澜健康产业研究院有限公司 | Composition with efficacies of inhibiting bacteria and diminishing inflammation |
| CN107737200A (en) * | 2017-10-19 | 2018-02-27 | 黑龙江隆浩生物科技股份有限公司 | A kind of citrus antibacterial liquid and preparation method thereof |
| CN107789253A (en) * | 2017-10-31 | 2018-03-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of anti-acne moisturizing skin care item and preparation method thereof |
| CN108096123A (en) * | 2018-02-09 | 2018-06-01 | 广州重生化妆品实业有限公司 | A kind of compound plant goes acne stoste and preparation method thereof |
| CN110227043A (en) * | 2018-03-06 | 2019-09-13 | 韩后化妆品股份有限公司 | Composition, preparation method and cosmetics with anti-corrosion moisture-keeping efficacy |
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| CN103393567A (en) * | 2013-07-29 | 2013-11-20 | 嘉文丽（福建）化妆品有限公司 | Anti-acne cosmetic containing Taiwan hibiscus taiwanensis extract |
| CN103816420A (en) * | 2014-03-07 | 2014-05-28 | 柯利佳 | Acne-removing composition prepared from crude medicines all being medicinal and edible |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103393567A (en) * | 2013-07-29 | 2013-11-20 | 嘉文丽（福建）化妆品有限公司 | Anti-acne cosmetic containing Taiwan hibiscus taiwanensis extract |
| CN103816420A (en) * | 2014-03-07 | 2014-05-28 | 柯利佳 | Acne-removing composition prepared from crude medicines all being medicinal and edible |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106511189A (en) * | 2017-01-06 | 2017-03-22 | 广州聚澜健康产业研究院有限公司 | Composition with efficacies of inhibiting bacteria and diminishing inflammation |
| CN107737200A (en) * | 2017-10-19 | 2018-02-27 | 黑龙江隆浩生物科技股份有限公司 | A kind of citrus antibacterial liquid and preparation method thereof |
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Application publication date: 20170531 |