CN108096123A - A kind of compound plant goes acne stoste and preparation method thereof - Google Patents
A kind of compound plant goes acne stoste and preparation method thereof Download PDFInfo
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- CN108096123A CN108096123A CN201810131867.9A CN201810131867A CN108096123A CN 108096123 A CN108096123 A CN 108096123A CN 201810131867 A CN201810131867 A CN 201810131867A CN 108096123 A CN108096123 A CN 108096123A
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- stoste
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
The invention discloses compound plants to go acne stoste, using each Plant Extracts, such as orange peel extract, peony extract, Honegsukle flower P.E, a variety of compound plant extracts, which are mutually mixed, to be made compound plant and goes acne stoste, utilize the characteristic of the antiphlogistic antibacterial of each plant extraction liquid, the barrier action of skin can be improved, reduce transepidermal water loss rate, improve the moistening effect of stoste；Inhibit melanocyte transport way, reduce face red spot, pigment deposition；Also, also play an important role of to expand blood vessel, the effect with brightening, dispelling spots, dispelling.It promotes blood circulation, improves capillary blood flow, accelerate skin metabolism and promote body temp.Resisting free radical prevents the injury of cell the variation of cell, makes skin health, bright.Inhibit melanocyte transport way, reduce face red spot, pigment deposition, there is apparent inhibitory action to inflammatory reaction, there is antibacterial and enhancing immune function, have and significantly go acne effect.
Description
Technical field
The present invention relates to moisture retention liquids, and in particular to a kind of compound plant added with various plants extracting solution go acne stoste and
Its preparation method.
Background technology
Since natural environment deteriorates increasingly, skin is caused to be damaged also and is on the rise, antibiotic in recent years is general in addition
It disorderly uses, human skin is made serious variation occur, there is an urgent need to be suitble to the product of human body natural's rule development by people.It is how pre-
The ectotoxic research core topic influenced as skin surface science of haze, Environmental Hormone, body.
To solve the above-mentioned problems, a large amount of significant exploration work have been done in industry, have emerged large quantities of stostes in the market,
It is mainly used for pre- grease-proof excessive secretion, controls bacteria breed, but these stoste generally use syntheticses are more, easily
Skin of face is made to generate irritation, so as to cause skin allergy and red and swollen phenomenon, and then skin is made to become more fragile sensitivity.
In conclusion how to provide a kind of compound plant to no skin irritation, moisturizing to go acne stoste is this field skill
Art personnel's urgent problem to be solved.
The content of the invention
For it is above-mentioned the problem of, the present invention provides a kind of compound plants to go acne stoste, avoids bringing human skin thorn
Swash property, face and body cleaning, the nursing of grease balance, the growth for inhibiting harmful bacteria, face and body skin is made to be kept for year
Gently, it is penetrating pale；Skin sense is soft and smooth and high resilience, while meets the product of skin youth demand.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：A kind of compound plant goes acne stoste, including with
Lower raw material (by weight),
The present invention also provides the preparation methods that a kind of compound plant goes acne stoste, comprise the following steps：
The deionized water of predetermined weight is carried out being warming up to 90-100 DEG C and keeps the temperature 30 minutes by step 1)；Cool down deionized water
During to 50 DEG C, raw material orange peel extract, borneol, Honegsukle flower P.E, peony extract, Cremophor RH40 are thrown respectively
Enter in tank, stir evenly for use；
Step 2) puts into the raw material after weighing and the deionized water of predetermined amount in agitated kettle A successively, is stirred, centrifuges
Processing, filtering obtain pre-mixing liquor；
Step 3) is by water phase deionized water and propylene glycol, biological carbohydrate gum -1,1,3 butylene glycol, allantoin, EDTA, hyalomitome
Sour sodium, Herba Dendrobii extract put into agitated kettle B and stir successively, and EDETATE SODIUM, Sodium Hyaluronate is made to solve homogeneously in deionization
In water, and 80-100 DEG C is heated to, and keeps the temperature 30 minutes；
Step 4) stirs the mixed liquor of above-mentioned agitated kettle B, and is cooled to 40-70 DEG C；
The pre-mixing liquor of step 2) and licorice are put into the agitated kettle B of step 3 and stirred by step 5) successively, with
After when being cooled to 40-50 DEG C, add in parahydroxyacet-ophenone, 1,2- hexylene glycols, and make the pH value of mixture for 6.2~6.8, and mixed
To get finished product when the viscosity for closing object is 1500~3500mpa.s.
Preferably, in step 2), the deionized water is 20-30 parts (by weight).
Preferably, in step 1) and step 2), the mixing speed is 60 revs/min, is kept stirring 20~30 minutes；
In step 5), the speed of agitator is 20~30 revs/min.
Preferably, in step 3), the ratio of deionized water and EDTA are 200：1.Mixed liquor is heated to 90 DEG C.
Preferably, in step 4), liquid is stirred, mixing speed is 35 revs/min, is cooled to 60 DEG C.
Compared with prior art, compound plant of the present invention goes acne stoste, is extracted using each Plant Extracts, such as orange peel
Object, peony extract, Honegsukle flower P.E etc., a variety of compound plant extracts, which are mutually mixed, to be made compound plant and goes acne stoste,
Utilize the characteristic of the antiphlogistic antibacterial of each plant extraction liquid, on the one hand, the barrier action of skin can be improved, reduced through epidermis dehydration
Rate improves the moistening effect of stoste；On the other hand, melanocyte transport way is can inhibit, reduces face red spot, pigment deposition；Also,
Also play an important role of to expand blood vessel, the effect with brightening, dispelling spots, dispelling.It promotes blood circulation, improves capillary blood flow, change
The infiltration problem of kind capillary accelerates skin metabolism and promotes body temp.Free radical is resisted to prevent the injury of cell
The only variation of cell makes skin health, bright.Inhibit melanocyte transport way, reduce face red spot, pigment deposition, it is anti-to inflammation
There should be apparent inhibitory action, there is antibacterial and enhancing immune function, have and significantly go acne effect.
Description of the drawings
Fig. 1 is the flow chart for the preparation method that a kind of compound plant of the present invention goes acne stoste.
Fig. 2 is the preparation process figure that a kind of compound plant of the present invention goes acne stoste.
Specific embodiment
The present invention provides a kind of compound plants to go acne stoste, including following components (by weight)：
First, orange peel extract
The anti-inflammatory effect of hesperidin may be by inhibiting the release of histamine to realize.Activity from orange peel is raw
Object flavones, containing 80% hesperidin, it is a kind of flavones being found in citrus peel, the cornstarch grape with 20%
There is highly-water-soluble after sugar binding.It promotes blood circulation in the following manner；Improve capillary blood flow；Improve blood capillary
The infiltration problem of pipe；Accelerate skin metabolism and promote body temp.
For centuries, orange peel is used for by Japanese in hot bath always, is on the one hand loosened because it has
On the other hand fragrant curative effect is to mitigate the problem of related with poor circulation, such as：Regular trick is ice-cold and some
The myalgia of type.Many skin problems are caused by the poor circulation of skin, such as：Livid ring around eye, the colour of skin without
Light, the colour of skin be dim and skin turgor, it can cause skin malnutrition, loses vigor and gloss.Pressure, cold day by day
Weather, lack movement or sleep insufficiency can all cause the cycling of skin bad.Its result is typically the same, i.e., skin is tired
Labor seems more aging.
Hesperidin is a kind of biological flavone, the active ingredient in orange peel, can be by promoting the blood circulation of skin and band
Carry out warm sensation, hesperidin dissolubility itself is low and is difficult with.When the cosmetics containing glycosyl hesperidin are applied in
When on skin, a kind of alpha-glucosidase being naturally occurring in skin can slowly release hesperidin.Hesperidin makes fragile
Capillary becomes strong and reduces their permeability.
By this mechanism, it can show when glycosyl hesperidin is applied on skin there is notable work to improving blood circulation
With.There is substantial amounts of capillary in skin：They play important work in skin-nourishing, body temperature control and asrteriectasia problem
With.
2nd, peony extract
Refrigeration function, Paeoniflorin have reduction effect to normal mouse body temperature, have conductive force to the mouse of artificial fever, resist
Scorching, antiulcer and anti-allergic effects.
Rat swell-foot caused by Paeoniflorin (50mg/kg, ig) Carrageenan and dextrose phenol has inhibitory action, to big
Mouse adjuvant-induced arthritis has preventive and therapeutic effect, plays the role of prevention effect to stress in rats ulcer and inhibits gastric secretion.Radix Paeoniae Alba is decocted
Agent has inhibitory action to some pathogenic bacterias and fungi.
Pharmacological action：Paeoniflorin shows inhibition to intestine in vitro, stomach movement in place and uterine smooth muscle, and energy antagonism is urged
Produce the contraction caused by element.Paeoniflorin has significant analgesic effect.It faints from fear caused by the medicinal extract energy antagonism strychnine of Chinese herbaceous peony.Radix Paeoniae Alba
Decoction has inhibitory action to some pathogenic bacterias and fungi.Paeoniflorin has normal body temperature cooling effect, and it is small to inhibit blood
Plate aggtegation.
In cosmetics/daily chemical products industry, peony extract is used to treat acne in cosmetics, and delays body tissue
Aging.It adds in shampoo, as natural on-off cycles of hair growth conditioner.
3rd, Honegsukle flower P.E
The action and efficacy of Honegsukle flower P.E is embodied in anti-inflammatory, two aspect of antibacterial.
The stem of honeysuckle, leaf, spending middle main ingredient, chlorogenic acid clinically plays an important role of antibacterial anti-inflammatory for chlorogenic acid.
Modern medicine study proves, honeysuckle is for streptococcus, staphylococcus, typhoid bacillus, shigella dysenteriae, large intestine and green
Purulence bacillus, Diplococcus pneumopniae, Bordetella pertussis, meningococcus etc. have stronger antibacterial power, to treatment influenza and
Inflammation has certain curative effect.
Pharmacological action：1. antibacterial and the effect for enhancing immune function：Experiments have shown that honeysuckle is to typhoid bacillus, paratyphoid bar
Bacterium, Escherichia coli, proteus, Pseudomonas aeruginosa, Bordetella pertussis, comma bacillus, staphylococcus, streptococcus, Diplococcus pneumopniae,
Meningococcus etc. has inhibitory action.
2nd, the synthesis of drug-fast bacteria protein is inhibited：Honegsukle flower P.E has the breathing of staphylococcus aureus resistance plant aobvious
Stimulation is write, Medicine and Surgery inflammation caused by being chiefly used in antibody-resistant bacterium such as treats pulmonary tuberculosis complicated respiratory tract infection, pneumonia, urgency
Property bacillary dysentery, diarrhea.Also it is useful for reducing bottleneck throat bacterial bearing rate.
Compound plant of the present invention is gone in acne stoste, is mixed with the compounds such as orange peel extract, peony extract, Honegsukle flower P.E
Plant extraction liquid promotes blood circulation；Improve capillary blood flow；Improve the infiltration problem of capillary；Accelerate skin
Metabolism and promotion body temp.Resisting free radical prevents the injury of cell the variation of cell, makes skin health, bright.
Inhibit melanocyte transport way, reduce face red spot, pigment deposition, have apparent inhibitory action to inflammatory reaction, have antibacterial and
Enhance the effect of immune function.
Embodiment 1：The compound plant goes acne stoste, including following components (by weight)：
Embodiment 2：The compound plant goes acne stoste, including following components (by weight)：
Embodiment 3：The compound plant goes acne stoste, including following components (by weight)：
Invention additionally provides a kind of preparation method for preparing the compound plant and going acne stoste, comprises the following steps：
The deionized water of predetermined weight is carried out being warming up to 90-100 DEG C and keeps the temperature 30 minutes by step 1)；Cool down deionized water
During to 50 DEG C, raw material orange peel extract, borneol, peony extract, Honegsukle flower P.E, Cremophor RH40 are thrown respectively
Enter in tank, stir evenly for use；
Step 2) puts into the raw material after weighing and the deionized water of predetermined amount in agitated kettle A successively, is stirred, centrifuges
Processing, filtering obtain pre-mixing liquor；
Step 3) is by water phase deionized water and propylene glycol, biological carbohydrate gum -1,1,3 butylene glycol, allantoin, EDTA, hyalomitome
Sour sodium, Herba Dendrobii extract put into agitated kettle B and stir successively, and EDETATE SODIUM, Sodium Hyaluronate is made to solve homogeneously in deionization
In water, and 80-100 DEG C is heated to, and keeps the temperature 30 minutes；
Step 4) stirs the mixed liquor of above-mentioned agitated kettle B, and is cooled to 40-70 DEG C；
The pre-mixing liquor of step 2) and licorice are put into the agitated kettle B of step 3 and stirred by step 5) successively, with
After when being cooled to 40-50 DEG C, add in parahydroxyacet-ophenone, 1,2- hexylene glycols, and make the pH value of mixture for 6.2~6.8, and mixed
To get finished product when the viscosity for closing object is 1500~3500mpa.s.
Preferably, in step 2), the deionized water is 20-30 parts (by weight).
Preferably, in step 1) and step 2), the mixing speed is 60 revs/min, is kept stirring 20~30 minutes；
In step 5), the speed of agitator is 20~30 revs/min.
In step 3), heating mixed liquor is to 90 DEG C.Deionized water and the ratio of EDTA are 200：1.
In step 4), liquid is stirred, mixing speed is 35 revs/min, is cooled to 60 DEG C.
Embodiment one
Compound plant goes the preparation method of acne stoste, comprises the following steps：
The deionized water of predetermined weight is carried out being warming up to 90 DEG C and keeps the temperature 30 minutes by step 1)；Deionized water is cooled down to 50
DEG C when, respectively by the orange peel extract of 3 parts of raw material, 0.5 part of borneol, 1 part of Honegsukle flower P.E, 5 parts of peony extracts,
In 0.5 part of Cremophor RH40 input tank, stir evenly for use；
Step 2) puts into the raw material after weighing and the deionized water of predetermined amount in agitated kettle A successively, is stirred, centrifuges
Processing, filtering obtain pre-mixing liquor；
Step 3) is by water phase deionized water and 3 parts of propylene glycol, 5 parts of biological carbohydrate gum -1,4 parts of 1,3 butylene glycol, 0.2
The allantoin, 0.05 part of EDTA, 0.25 part of Sodium Hyaluronate, 5 parts of Herba Dendrobii extract of part are put into agitated kettle B simultaneously successively
Stirring, makes EDETATE SODIUM, Sodium Hyaluronate uniform dissolution in deionized water, and is heated to 85 DEG C, and keeps the temperature 30 minutes；
Step 4) stirs the mixed liquor of above-mentioned agitated kettle B, and is cooled to 45 DEG C；
Step 5) puts into the pre-mixing liquor of step 2) and 4 parts of licorice in the agitated kettle B of step 3) simultaneously successively
Stirring, when being then cooled to 40 DEG C, parahydroxyacet-ophenone, 0.3 part of 1, the 2- hexylene glycol of 0.3 part of addition, and make the PH of mixture
Be worth for 6.5, and the viscosity of mixture when being 2000mpa.s to get finished product.
In order to which experiment is compared, influence of the different moisturizing stostes to skin is detected, provides matching somebody with somebody for one group of comparison stoste
Than (by weight percentage)：
Verification result：
1 compound plant of the present invention of table goes acne stoste to influence (acute skin irritation to skin irritation with comparison moisturizing stoste
Experiment)
| Name of product | Skin wound repair degree |
| Compare case | 1 |
| Case 1 | 0 |
| Case 2 | 0 |
| Case 3 | 0 |
It can be seen that the compound plant of present invention addition plant extract composition goes acne stoste to reduce very skin irritation
It is more.
2nd, the evaluation method (QB/T 2738-2012) of daily chemical products antibacterial bacteriostatic effect
Fungistatic effect evaluates (comparison case)
Fungistatic effect evaluates (case 1)
Fungistatic effect evaluates (case 2)
Fungistatic effect evaluates (case 3)
Analysis table product antibacterial bacteriostatic effect
| Name of product | To the bacteriostasis rate of propionibacterium acnes | To the bacteriostasis rate of staphylococcus aureus |
| Compare case | B3 grades | B3 grades |
| Case 1 | B2 grades | B2 grades |
| Case 2 | B1 grades | B1 grades |
| Case 3 | B1 grades | B1 grades |
It is significantly carried it can be seen that the compound plant of present invention addition plant extract composition goes acne stoste to have fungistatic effect
It is high.
The present invention is described in detail above, it is described above, it is only the preferred embodiments of the invention, when cannot
Limit the application practical range, i.e., it is all to make equivalent changes and modifications according to the application scope, it all should still belong to covering scope of the present invention
It is interior.
Claims (10)
1. a kind of compound plant goes acne stoste, it is characterised in that：Including following components (by weight)：
2. compound plant according to claim 1 goes acne stoste, it is characterised in that：Including following components (by weight
Meter)：
3. compound plant according to claim 1 goes acne stoste, it is characterised in that：Including following components (by weight
Meter)：
4. compound plant according to claim 1 goes acne stoste, it is characterised in that：Including following components (by weight
Meter)：
5. the preparation method of acne stoste is gone based on compound plant described in claim 1, it is characterised in that comprise the following steps：
The deionized water of predetermined weight is carried out being warming up to 90-100 DEG C and keeps the temperature 30 minutes by step 1)；Deionized water is cooled down to 50
DEG C when, respectively by raw material orange peel extract, borneol, Honegsukle flower P.E, peony extract, Cremophor RH40 put into tank
In, it stirs evenly for use；
Step 2) puts into the raw material after weighing and the deionized water of predetermined amount in agitated kettle A successively, is stirred, at centrifugation
Reason, filtering obtain pre-mixing liquor；
Step 3) is by water phase deionized water and propylene glycol, biological carbohydrate gum -1,1,3 butylene glycol, EDTA, allantoin, hyaluronic acid
Sodium, Herba Dendrobii extract put into agitated kettle B and stir successively, and EDETATE SODIUM, Sodium Hyaluronate is made to solve homogeneously in deionized water
In, and 80-100 DEG C is heated to, and keep the temperature 30 minutes；
Step 4) stirs the mixed liquor of above-mentioned agitated kettle B, and is cooled to 40-70 DEG C；
The pre-mixing liquor of step 2) and licorice are put into the agitated kettle B of step 3 and stirred by step 5) successively, then drop
When temperature is to 40-50 DEG C, parahydroxyacet-ophenone, 1,2- hexylene glycols are added in, and makes the pH value of mixture for 6.2~6.8, and mixture
Viscosity be 1500~3500mpa.s when to get finished product.
6. compound plant according to claim 5 goes the preparation method of acne stoste, it is characterised in that：In step 2), institute
Deionized water is stated as 20-30 parts (by weight).
7. compound plant according to claim 5 goes the preparation method of acne stoste, it is characterised in that：In step 1) and step
2) in, the mixing speed is 60 revs/min, is kept stirring 20~30 minutes；In step 5), the speed of agitator for 20~
30 revs/min.
8. compound plant according to claim 5 goes the preparation method of acne stoste, it is characterised in that：In step 3), add
Hot mixed liquor is to 90 DEG C.
9. compound plant according to claim 5 goes the preparation method of acne stoste, it is characterised in that：In step 3), go
The ratio of ionized water and EDTA are 200：1.
10. compound plant according to claim 5 goes the preparation method of acne stoste, it is characterised in that：In step 4), stir
Mixed liquor is mixed, mixing speed is 35 revs/min, is cooled to 60 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201810131867.9A CN108096123A (en) | 2018-02-09 | 2018-02-09 | A kind of compound plant goes acne stoste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810131867.9A CN108096123A (en) | 2018-02-09 | 2018-02-09 | A kind of compound plant goes acne stoste and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN108096123A true CN108096123A (en) | 2018-06-01 |
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ID=62222148
Family Applications (1)
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|---|---|---|---|
| CN201810131867.9A Pending CN108096123A (en) | 2018-02-09 | 2018-02-09 | A kind of compound plant goes acne stoste and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653039A (en) * | 2018-06-19 | 2018-10-16 | 广州高蒂丝生物科技有限公司 | A method of removing acne Essence using fresh medicinal material preparation |
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| CN107213069A (en) * | 2017-07-04 | 2017-09-29 | 黄美风 | A kind of U.S. face film and preparation method thereof |
| CN107349149A (en) * | 2017-07-25 | 2017-11-17 | 广州铭心化妆品有限公司 | A kind of anti-acne essence and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105769707A (en) * | 2016-04-22 | 2016-07-20 | 欧标（广州）化妆品有限公司 | Composition for removing acnes and application of composition in cosmetics |
| CN107019657A (en) * | 2016-12-14 | 2017-08-08 | 上海辉文生物技术股份有限公司 | A kind of skin whitening, moisturizing composition and preparation method thereof and application method |
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| CN107213069A (en) * | 2017-07-04 | 2017-09-29 | 黄美风 | A kind of U.S. face film and preparation method thereof |
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| CN108653039A (en) * | 2018-06-19 | 2018-10-16 | 广州高蒂丝生物科技有限公司 | A method of removing acne Essence using fresh medicinal material preparation |
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Inventor after: Chen Bo Inventor after: Jiang Min Inventor before: Jiang Min |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180601 |