CN101297857B - Chinese medicine preparation for treating recessive mastitis of cow and preparation method thereof - Google Patents
Chinese medicine preparation for treating recessive mastitis of cow and preparation method thereof Download PDFInfo
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- CN101297857B CN101297857B CN2007100600176A CN200710060017A CN101297857B CN 101297857 B CN101297857 B CN 101297857B CN 2007100600176 A CN2007100600176 A CN 2007100600176A CN 200710060017 A CN200710060017 A CN 200710060017A CN 101297857 B CN101297857 B CN 101297857B
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Abstract
The invention relates to a traditional Chinese medicine preparation for treatment for hidden mastitis of cows, which is characterized in that the traditional Chinese medicine preparation is prepared by mixing Chinese herbal medicines with the following parts by weight: 80 to 120 parts of membranous milkvetch root, 50 to 70 parts of pilose Asiabell root, 32 to 48 parts of Chinese angelica, 32 to 48 parts of honeysuckle flower and 50 to 70 parts of Indian buead. The preparation method is as follows: all the components are smashed into ultra-fine powder, and the powder is evenly mixed according to a proportion, or the heating extraction is carried out to prepare oral liquor, medical drinking tablets are weighed according to the proportion, 5 to 10 times of water is added for soaking for 20 to 40 minutes and carrying out the decoction for 50 to 80 minutes, the mixture is concentrated to that each milliliter contains 0.5 to 1g of the raw medicine after the filtration, thus preparing the traditional Chinese medicine preparation. The traditional Chinese medicine preparation has reasonable formula and simple preparation process; the adopted ingredients of the Chinese herbal medicines have wide range of resources, low cost and high cure rate; the medicine has no residues, no toxicity or side effects and is easy to be absorbed by the cows. The traditional Chinese medicine preparation has significant effects of sterilization, detoxification and improvement of immune function, which can effectively treat the hidden mastitis of the cows and shorten the recovery period, as well as be conductive to the improvement of the milk quality of the cows and the increase of the milk production.
Description
Technical field
The present invention relates to Chinese medicine preparation for the treatment of cow disease and preparation method thereof, particularly a kind of Chinese medicine preparation for the treatment of bovine subclinical mastitis and preparation method thereof.
Background technology
Along with the raising of people's living standard, the enhancing of health and environmental consciousness, the change of diet structure, milk changes to daily beverage from nutritional supplement just gradually, and the milk consumption market enlarges rapidly, makes that domestic and international dairy is flourish.
At present, latent mammitis is suffered from cattle and is normally not present tangible clinical symptoms, milch cow body condition, spiritual no any unusual, and breast does not have redness, high thermal phenomenon, pushes and does not have pain.Only find when milking that the milk color is pale red or newborn sheet or the ziega that solidifies arranged that the milk outward appearance that has is normal, and is positive when checking with ethanol.The sick cattle of perinatal infection, prolonged lochia secondary latent mammitis is flowed out the malodorous secretions of canescence from vaginal orifice.Since the environmental pollution secondary can go out pathogenic bacteria from fresh milk culture of isolated.
After the ill milch cow of existing treatment anti-microbial type medicine was taken, toxic and side effects was bigger, and clinical effectiveness is not obvious, has a series of problems such as drug residue and environmental pollution, brings another suffering to animal husbandry.
Therefore, a kind of specific medicament for the treatment of bovine subclinical mastitis of research and development is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide a kind of and have no side effect, treat safely and effectively Chinese medicine preparation of bovine subclinical mastitis and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of Chinese medicine preparation for the treatment of bovine subclinical mastitis is characterized in that by the following portions by weight mixing Chinese medicinal herbs formulated: 80～120 parts of the Radixs Astragali, 50～70 parts of Radix Codonopsis, 32～48 parts of Radix Angelicae Sinensis, 32～48 parts of Flos Loniceraes, 50～70 parts in Poria.
Described various component optimum ratio amount is: 100 parts of the Radixs Astragali, 60 parts of Radix Codonopsis, 40 parts of Radix Angelicae Sinensis, 40 parts of Flos Loniceraes, 60 parts in Poria.
A kind of preparation method for the treatment of the Chinese medicine preparation of bovine subclinical mastitis is characterized in that above-mentioned each component is ground into behind the ultra-micro powder uniform mixing in proportion; Or heating extraction makes oral liquid, promptly takes by weighing the medicine decoction pieces in proportion, adds 5～10 times of water, soaks 20～40 minutes, decocts 50～80 minutes, is concentrated into every milliliter after filtering and contains crude drug 0.5～1g, can make.
The characteristic of each component drug is as follows:
The Radix Astragali: the astragaloside that contains in the Radix Astragali extract has invigorating QI to consolidate the body surface resistance, diuresis toxin expelling, evacuation of pus, holds back the effect of skin ulcer, granulation promoting.Be applicable to symptoms such as food-intake reduction and feces are thin, Radix Astragali extract has enhancing immunity, strengthen energy, reduce myocardial oxygen consumption, decreased heart rate, the diastole coronary artery, strengthen effects such as myocardial contraction, also have the effect of enhancing immunity simultaneously, can induce body to produce interferon, the effect that also has heat-clearing and toxic substances removing, effectively relief of symptoms.
Radix Codonopsis: main component is that root contains triterpenoid compound freidelin, alnulin acetas, bessisterol and glycoside thereof, Δ 7-stigmastenol and glycoside thereof, spinach sterone.Other contains atractylenoide, atractyloide, syringic aldehyde, Syringin, vanillic acid, 5-hydroxyl-2-piconol, α-Fu Nan carboxylic acid, n-hexyl-β-D-glycoside, ethyl-α-D-fructofuranoside, and nicotinic acid, 4 kinds of heteropolysaccharide and monosaccharide etc.Still contain the I of tangshenoside, codonolactone and codopiloic acid.Feeble QI perfume (or spice), sweet in the mouth.Have invigorating middle warmer, QI invigorating, the effect of nourishing blood, promote the production of body fluid.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica.Autumn end excavates, and removes fibrous root and silt, treat that moisture evaporates slightly after, tie into wisp, last canopy is with pyrotechnics smoke-dried beancurd slowly.Character this product is similar round or irregular thin slice, and tangent plane has the light brown ring grain, and matter is pliable and tough, buff, slightly focal spot.Strong fragrance is arranged, and sweet in the mouth, suffering, little hardship, strongly fragrant have wine aroma; Warm in nature, return liver, the heart, spleen channel, sweet Wen Zhirun enriches blood and invigorates blood circulation, reducing swelling and alleviating pain, granulation promoting is controlled ulcer sores, nourishes blood, loosening bowel to relieve constipation.
Flos Lonicerae: meridian distribution of property and flavor, sweet cold, return lung, the heart, stomach warp, heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, modern pharmacological research shows that it has the effect of antibiotic, antiviral, inhibition ulcer and raise immunity, and test shows that Flos Lonicerae all has inhibitory action to Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, bacillus pyocyaneus, bordetella pertussis, vibrio cholera, staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus etc.Have the broad-spectrum antiseptic drug effect, strengthen immunity of organisms, mammitis of cow is had specially good effect.Effects such as that the chlorogenic acid that is contained in the Flos Lonicerae has is antibiotic, antiviral, hemostasis, anti-hepatitis also have the effect of enhancing immunity simultaneously, can induce body to produce interferon, improve the body function of milch cow, mitigate the disease; The chlorogenic acid that is contained in the Flos Lonicerae also has the effect of heat-clearing and toxic substances removing in addition, effectively relief of symptoms.
Poria: be the sclerotium of porous strain parasitic plant (straight bacterium) Poria Poria cocos (Schw.) wolf.Poria class ball or piece shape, the rough apparent wrinkle of the thin palm fibre of skin, the section white lead granulates, and the spleen invigorating eliminating dampness by diuresis is calmed the nerves again.Composition: contain triterpene acids (the not acid of pachymic acid, soil, eburicoic acid, loose Siberian cocklebur acid, loose Siberian cocklebur eo-acid and ergosterol; Dehydrogenation pachymic acid, dehydrogenation soil not acid and polyporic acid are still arranged).Polysaccharide (being mainly pachyman) in addition, contains histidine, adenine, choline, the poly-enzyme of β-Poria, protease, lipase, fat, lecithin etc.The property sweet light flat, go into the heart, lung, spleen, urinary bladder channel.Promoting diuresis to eliminate damp pathogen, the midship that disappears, spleen invigorating invigorating middle warmer, mind tranquilizing and the heart calming.
All medicines match, and endogenous dampness is got clearly, and interior-heat must be separated, and improve milch cow body function, mitigate the disease; After taking, ill milch cow can make all sxs and being fully recovered.
Medicine of the present invention is that pure Chinese herbal medicine is formed reasonable recipe.The combination principle of Chinese medicine is " efficacy enhancing and toxicity reducing ", and therefore, the different pharmacological action that medicine embodied of compatibility is also different.The said medicine compatibility, full side is able to treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors.Across-the-board regulation, Yin Yang balancing.Mix the medicine that above-mentioned raw materials is made, medicine of the present invention has significant effect to bovine subclinical mastitis, and curative effect is much higher than the medicine of folk prescription, and unique curative effect is arranged.The present invention is according to the diagnosis and treatment method of China's " comprehensive adjustment, mass prevention and mass treatment ", and in line with the principle of " invigorating the spleen to clear away damp pathogen, YIN nourishing and QI supplementing, heat-clearing and toxic substances removing ", the control rate in clinical trial reaches more than 90%, and unique curative effect is arranged.
The invention has the beneficial effects as follows: reasonable recipe, preparation technology is simple; Chinese crude drug is carried out micronizing, make it pass through 100～300 mesh sieves, destroy plant cell wall to greatest extent, solved the deficiency that Chinese medicine powder crude fiber content height, effective ingredient are difficult to stripping; Heating extraction is made oral liquid, uses conveniently, absorbs rapidly.Medicinal herb components wide material sources, the cost that adopts is low, cure rate is high; The medicine noresidue has no side effect, and is easy to milch cow and absorbs.Have the effect that significant sterilization is detoxified and improved body's immunity, effectively treat bovine subclinical mastitis, shorten the period of convalescence; And be beneficial to and improve the cow producing milk quality, improve milk yield.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
Prescription proportioning (by every part of 1g): Radix Astragali 100g, Radix Codonopsis 60g, Radix Angelicae Sinensis 40g, Flos Lonicerae 40g, Poria 60g.
Above-mentioned each component is checked routinely, be ground into ultra-micro powder, weighing mixing in proportion behind 100～300 mesh sieves excessively, packing can make; Or heating extraction makes oral liquid, promptly takes by weighing the medicine decoction pieces in proportion, and adding 5 times of water is 1500g, soaks 20～40 minutes, decocts 50～80 minutes, is concentrated into every milliliter after filtering and contains crude drug 0.5～1g, can make.
Embodiment 2
Prescription proportioning (by every part of 1g): Radix Astragali 82g, Radix Codonopsis 50g, Radix Angelicae Sinensis 32g, Flos Lonicerae 32g, Poria 50g.
Above-mentioned each component is checked routinely, be ground into ultra-micro powder, weighing mixing in proportion behind 100～300 mesh sieves excessively, packing can make; Or heating extraction makes oral liquid, promptly takes by weighing the medicine decoction pieces in proportion, and adding 7 times of water is 1722g, soaks 20～40 minutes, decocts 50～80 minutes, is concentrated into every milliliter after filtering and contains crude drug 0.5～1g, can make.
Embodiment 3
Prescription proportioning (by every part of 1g): Radix Astragali 118g, Radix Codonopsis 70g, Radix Angelicae Sinensis 48g, Flos Lonicerae 48g, Poria 70g.
Above-mentioned each component is checked routinely, be ground into ultra-micro powder, weighing mixing in proportion behind 100～300 mesh sieves excessively, packing can make; Or heating extraction makes oral liquid, promptly takes by weighing the medicine decoction pieces in proportion, and adding 10 times of water is 3540g, soaks 20～40 minutes, decocts 50～80 minutes, is concentrated into every milliliter after filtering and contains crude drug 0.5～1g, can make.
Clinical trial:
Application example 1
Shanxi, address ubac grandson
The kind Fresian
45 cow heads do not have tangible clinical symptoms, milch cow body condition, spiritual no any unusual, and breast does not have redness, high thermal phenomenon, pushes and does not have pain.Only find when milking that the milk color is pale red or newborn sheet or the ziega that solidifies arranged that the milk outward appearance that has is normal, and is positive when checking with ethanol.Every cow head is used drug powder 250～500g of the present invention or oral liquid 250～1000ml every day, logotype 7 days, and the symptom complete obiteration, body recovery is normal, and effective percentage is 93.3%.
Application example 2
Shanxi, address ubac poplar
The kind Fresian
32 cow heads do not have tangible clinical symptoms, milch cow body condition, spiritual no any unusual, and breast does not have redness, high thermal phenomenon, pushes and does not have pain.Only find when milking that part milk has newborn sheet or the ziega that solidifies, CMT reagent tests positive.Every cow head is used drug powder 250～500g of the present invention or oral liquid 250～1000ml every day, logotype 7 days, and the symptom complete obiteration, body recovery is normal, and effective percentage is 93.75%.
During application, preparation of the present invention evenly admixed in the milk cow forage or add water in the ratio of milch cow body weight 0.05～0.1% gavage, the ill milch cow and observe its patient's condition fed, course of treatment on every Mondays, use 1～2 the course of treatment effect highly significant.
More than illustrate medicine of the present invention and have the high good result of cure rate, cure rate all can reach more than 90%.
Above-mentioned detailed description of the Chinese medicine preparation and preparation method thereof of treatment bovine subclinical mastitis being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. a Chinese medicine preparation for the treatment of bovine subclinical mastitis is characterized in that by the following portions by weight mixing Chinese medicinal herbs formulated: 80～120 parts of the Radixs Astragali, 50～70 parts of Radix Codonopsis, 32～48 parts of Radix Angelicae Sinensis, 32～48 parts of Flos Loniceraes, 50～70 parts in Poria.
2. the Chinese medicine preparation of treatment bovine subclinical mastitis according to claim 1 is characterized in that described various set of dispense is made a gesture of measuring and is 100 parts of the Radixs Astragali, 60 parts of Radix Codonopsis, 40 parts of Radix Angelicae Sinensis, 40 parts of Flos Loniceraes, 60 parts in Poria.
3. the preparation method of the Chinese medicine preparation of a treatment bovine subclinical mastitis according to claim 1 and 2 is characterized in that above-mentioned each component is ground into behind the ultra-micro powder uniform mixing in proportion; Or heating extraction makes oral liquid, promptly takes by weighing the medicine decoction pieces in proportion, adds 5～10 times of water, soaks 20～40 minutes, decocts 50～80 minutes, is concentrated into every milliliter after filtering and contains crude drug 0.5～1g, can make.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100600176A CN101297857B (en) | 2007-10-25 | 2007-10-25 | Chinese medicine preparation for treating recessive mastitis of cow and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100600176A CN101297857B (en) | 2007-10-25 | 2007-10-25 | Chinese medicine preparation for treating recessive mastitis of cow and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
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| CN101297857A CN101297857A (en) | 2008-11-05 |
| CN101297857B true CN101297857B (en) | 2010-09-01 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104800421B (en) * | 2015-04-23 | 2018-09-21 | 河南省首家中兽医药服务有限公司 | A kind of traditional Chinese powder medicine of prevention and treatment cow subclinical mastitis |
| CN106074820A (en) * | 2016-07-22 | 2016-11-09 | 太仓市爱农奶牛专业合作社 | A kind of newborn room injection treating mammitis of cow and preparation method thereof |
| CN113599470A (en) * | 2021-08-07 | 2021-11-05 | 青岛农业大学 | Traditional Chinese medicine composition for treating sheep intestinal toxemia |
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2007
- 2007-10-25 CN CN2007100600176A patent/CN101297857B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 钟聪明.中西兽医结合防治乳牛乳房炎.福建畜牧兽医.2005,27(6),56-57. * |
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Owner name: TIANJIN TIANHELI PHARMACEUTICAL R + D CO., LTD. Free format text: FORMER OWNER: TIANJIN SHENGJI GROUP CO., LTD. Effective date: 20121016 |
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Free format text: CORRECT: ADDRESS; FROM: 301609 JINGHAI, TIANJIN TO: 300113 NANKAI, TIANJIN |
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Effective date of registration: 20121016 Address after: 316, room 9, science and Technology Park, Nankai Science Park, No. 300113 Yibin Road, Tianjin, Nankai District Patentee after: Tianjin Tianheli Pharmaceutical R & D Co.,Ltd. Address before: 301609. 2, Tianyu Science Park, Jinghai, Tianjin Patentee before: Tianjin Shengji Group Co., Ltd. |
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Granted publication date: 20100901 Termination date: 20121025 |