CN102671088A - Traditional Chinese medicine combination for treating tuberculosis - Google Patents

Traditional Chinese medicine combination for treating tuberculosis Download PDF

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Publication number
CN102671088A
CN102671088A CN2012101805865A CN201210180586A CN102671088A CN 102671088 A CN102671088 A CN 102671088A CN 2012101805865 A CN2012101805865 A CN 2012101805865A CN 201210180586 A CN201210180586 A CN 201210180586A CN 102671088 A CN102671088 A CN 102671088A
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chinese medicine
traditional chinese
medicine combination
rhizoma
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许延海
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Abstract

The invention discloses a traditional Chinese medicine combination for treating tuberculosis and belongs to the field of traditional Chinese medicines. According to the traditional Chinese medicine combination, fragrant solomonseal rhizome, lily, common bletilla pseudobulb, lalang grass rhizome, agrimonia pilosa ledeb, houttuynia cordata, white mulberry root-bark, panax notoginseng powder, stemona, turtle shell, licorice and tree peony bark are adopted to be combined, interact and complement and benefit each other. The traditional Chinese medicine combination has the effects of nourishing yin and moistening the lung, relieving a cough and eliminating phlegm. The traditional Chinese medicine combination is low in medicine cost and free of any side effect, the therapeutic effect is remarkable, the total effective rate in one course of treatment is 95%, and the total effective rate in two courses of treatment is 97.5%.

Description

The phthisical Chinese medicine composition of a kind of treatment
Technical field
[0001] the invention discloses a kind of Chinese medicine composition, the phthisical Chinese medicine composition of especially a kind of treatment.
Background technology
[0002] pulmonary tuberculosis is a kind of chronic pneumonia infection disease that is caused by tubercule bacillus.The primary disease traditional Chinese medical science belongs to " pulmonary tuberculosis ", " corpse notes ", " hectic fever due to YIN-deficiency " category.Motherland's medical science is thought lung tender dirty for void clearly, and not anti-heresy is invaded, and corrodes in lung like the consumptive disease worm, and lung qi is impaired, clearly respectful makes that not all right the bright Tianjin of asthenic fire forms expectorant then for coughing, and the damage lung network is then spat blood; Deficiency of kidney yin, the not good fire of water, the heart-fire disturbance influences the mind, and urgent body fluid leaks, then vexed uneasiness, cardiopalmus, night sweat; Deficiency of YIN-essence, YIN failing to keep YANG well, low grade fever then, hectically flushed cheeks, emaciated physique loses weight; Deficiency of both the splenic and pulmonary QI, thus loss of appetite, spiritual fatigue and weak.
At present, mainly be the chemicals that doctor trained in Western medicine is used for phthisical treatment, this is treated, and not only dosage is big; And administration time is long, is easy to develop immunity to drugs, very easily recurrence; In addition, the toxic and side effects of chemicals is bigger to people's liver, renal damage, and a lot of patients do not cure; But but caused the generation of other diseases, caused suffering to the patient.
Summary of the invention
Technical assignment of the present invention is to provide a kind of treatment phthisical Chinese medicine composition to the deficiency of above prior art, and said composition has the effect of nourishing YIN and moistening the lung, eliminating phlegm and stopping cough.
The present invention selects Rhizoma Polygonati Odorati, Bulbus Lilii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Imperatae, Herba Agrimoniae, Herba Houttuyniae, Cortex Mori, Radix Notoginseng powder, the Radix Stemonae, Carapax Trionycis, Radix Glycyrrhizae, Cortex Moutan to make up; Make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat pulmonary tuberculosis.
Wherein: Rhizoma Polygonati Odorati: for liliaceous plant ( Polygonatum odoratum(Mill.) Rhizoma Polygonati Odorati rhizome Druce).Sweet in the mouth, property is flat.Return lung; The stomach warp.Has nourishing YIN and moistening the lung; The effect of nourishing the stomach to promote the production of body fluid.These article have and promote laboratory animal antibody to generate, and that improves macrophage engulfs percent and phagocytic index, promotes interferon synthetic, suppresses growth of bacillus tubercle.
Bulbus Lilii: be the dry meat scale leaf of liliaceous plant tiger lily Lilium lancifolium Thunb., Bulbus Lilii Lilium brownii F.E.Brown var. viridulum Baker or Bulbus lilii concoloris Bulbus Lilii (Lilium tenuifolium) Lilium pumilum DC..Sweet in the mouth, cold nature.GUIXIN, lung meridian.Has nourishing YIN and moistening the lung, eliminating phlegm and stopping cough, the effect of clearing away heart-fire for tranquillization.
Pseudobulbus Bletillae (Rhizoma Bletillae): be the dry tuber of orchid Pseudobulbus Bletillae (Rhizoma Bletillae) Bletilla striata (Thunb.) Reichb. f..Nature and flavor are bitter, sweet, puckery, are slightly cold.Return lung, liver, stomach warp.Has tonifying the lung, astringing to arrest bleeding, the effect of detumescence and promoting granulation.The immersion of Pseudobulbus Bletillae (Rhizoma Bletillae) ethanol has inhibitory action to staphylococcus aureus, bacillus subtilis, Bacillus tuberculosis; The water logging agent has inhibitory action to microsporon audouini; 3 biphenyl classes and 2 luxuriant and rich with fragrance compounds of two hydrogen that Pseudobulbus Bletillae (Rhizoma Bletillae) contained have inhibitory action to staphylococcus aureus, bacillus subtilis, Candida albicans ATCC1057 and Trichophyton QM248.
Rhizoma Imperatae: be grass Herba Imperatae lmperata cylindrica (L.) Beauv.var.major (Nees) C.K.Hubb rhizome.Nature and flavor are sweet, cold.Go into lung, stomach, small intestine meridian.Has cooling blood for hemostasis, the clearing away heat and promoting diuresis effect.These article can significantly shorten hemorrhage and clotting time, and its water decoction and water logging agent have diuresis, act in the time of 5~10 days obviously with administration; Streptococcus pneumoniae, micrococcus catarrhalis, hemophilus influenza, staphylococcus aureus and Fu Shi, Song Shi dysentery bacterium etc. there is inhibitory action.
Herba Agrimoniae: be the full leaf of rosaceous plant Agrimony Agrimonia.Nature and flavor are bitter, puckery, and are flat.GUIXIN, Liver Channel.Has anastaltic effect.The hot water of Herba Agrimoniae or ethanol immersion all have inhibitory action to bacillus subtilis, staphylococcus aureus, escherichia coli, bacillus pyocyaneus, shigella flexneri and Bacillus typhi etc. in vitro, and the Bacillus tuberculosis is also had inhibitory action.
Herba Houttuyniae: be the dry above water of Saururaceae herbaceos perennial Herba Houttuyniae.Cold nature, bitter in the mouth.Return lung meridian, bladder, large intestine channel.Effect with heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome.Cure mainly the lung abscess vomiting pus; The expectorant dyspnea of heat type such as coughs at disease.Carry in the Herba Houttuyniae a kind of yellow oil, various microorganisms (especially yeast and mycete) are all had inhibitory action, streptococcus, staphylococcus aureus, hemophilus influenza, micrococcus catarrhalis, the streptococcus pneumoniae of hemolytic had the obvious suppression effect.
Cortex Mori: be the root bark of moraceae plants Mulberry Morus alba L..Sweet in flavor and cold in property, go into lung meridian.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Be used for the lung-heat cough with asthma, the edema of the face, diseases such as dysuria.The plain AuwanonC of Cortex Mori root, J, L and sanggenon A, B, C, D have antibacterial activity to golden Portugal bacterium and bacillus subtilis; Kuwanon J, L and sanggenon A, B, C are to class streptococcus and Cortex Mori root element, and kuwanon C, L, A respectively have antibacterial activity to smegmatis mycobacterium.
Radix Notoginseng powder: be plant Radix Notoginseng (formal name used at school: rhizome goods Panax pseudo-ginseng).Warm in nature, sweet and slightly bitter taste is gone into liver, stomach, large intestine channel.Radix Notoginseng has good hemostasia effect, can obviously shorten hemorrhage and clotting time.Evident in efficacy to pulmonary tuberculosis and pulmonary abscess merging spitting of blood patient.
The Radix Stemonae: be the dried root of Stemonaceae plant Radix Stemonae Stemona sessilifolia (Miq.) Miq., Radix stemonae japonicae Stemona japonica (Bl.) Miq. or radix stemonae tuberosae Stemona tuberosa Lour..Nature and flavor are sweet, bitter, tepor.Return lung meridian.Cure mainly nourishing the lung to keep the adverse QI downward cough-relieving.Radix Stemonae alkaloid can reduce the irritability of animal breath maincenter, suppresses coughre flex and the effect of tool antitussive; Radix Stemonae decoct and pure preserved material all have inhibitory action in various degree to streptococcus pneumoniae, beta hemolytic streptococcus, meningococcus, staphylococcus aureus, Staphylococcus albus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, diphtheria corynebacterium, pneumobacillus, bacillus pestis, anthrax bacillus, bacillus subtilis and vibrio cholera, Bacillus tuberculosis etc.
Carapax Trionycis: be the carapace of Trionychidae animal Trionyx sinensis Wiegmann Trionyx sinensis Wiegmann.Nature and flavor are salty, cold.Return liver, kidney channel.Has nourishing YIN for suppressing the hyperactive YANG, the effect of hard masses softening and resolving.
Cortex Moutan: be the perennial machaka plant of Ranunculaceae Paeonia suffruticosa Paeonia suffruticosaAndr. dry root bark.Cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Effect with clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.The Cortex Moutan decoct all has stronger antibacterial action to bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, Bacillus proteus, bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, vibrio cholera etc.
Radix Glycyrrhizae: dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensisFisch., Glycyrrhiza inflata Bat. G. inflataOr Glycyrrhiza glabra L. Bat., G. glabraL. root and rhizome.Property is put down, and sweet in the mouth is returned 12 warps.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.
The present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, like pill, oral liquid etc.For example can these crude drug be used decocting,, add antiseptic and process oral liquid through filtering filtrating; Also can directly take decoction in case of necessity.
The present invention has the effect of nourishing YIN and moistening the lung, eliminating phlegm and stopping cough, have safe and reliable, have no side effect short treating period; Characteristics such as evident in efficacy; According to clinical 120 routine patients are observed statistics, take medicine total effective rate course of treatment total effective rate 95%, two course of treatment 97.5% of the present invention.
The specific embodiment
Embodiment one, 10 parts of Rhizoma Polygonati Odorati, 10 parts of Bulbus Liliies, 10 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Rhizoma Imperataes, 25 parts of Herba Agrimoniaes, 25 parts of Herba Houttuyniae, 10 parts of Cortex Mori, 5 parts of Radix Notoginseng powder, 10 parts of the Radixs Stemonae, 10 parts of Carapax Trionycis, 1 part in Radix Glycyrrhizae, 10 parts of Cortex Moutans.
Embodiment two, 12 parts of Rhizoma Polygonati Odorati, 12 parts of Bulbus Liliies, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Rhizoma Imperataes, 30 parts of Herba Agrimoniaes, 30 parts of Herba Houttuyniae, 12 parts of Cortex Mori, 9 parts of Radix Notoginseng powder, 12 parts of the Radixs Stemonae, 12 parts of Carapax Trionycis, 3 parts in Radix Glycyrrhizae, 12 parts of Cortex Moutans.
Embodiment three, 15 parts of Rhizoma Polygonati Odorati, 15 parts of Bulbus Liliies, 20 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 25 parts of Rhizoma Imperataes, 35 parts of Herba Agrimoniaes, 35 parts of Herba Houttuyniae, 15 parts of Cortex Mori, 15 parts of Radix Notoginseng powder, 15 parts of the Radixs Stemonae, 15 parts of Carapax Trionycis, 5 parts in Radix Glycyrrhizae, 15 parts of Cortex Moutans.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept out-patient's 120 examples for medical treatment, 25-62 years old ages, 48 years old mean age, wherein, male's 73 examples, women's 47 examples.
Two, diagnostic criteria
1, the initial stage only feels tired weak, dry cough, and inappetence, body is become thin gradually, and (coughing up) blood can appear coughing in seriously ill person, hectic fever, flushed cheeks, night sweat, body disease such as obviously become thin.2, the close contact history with pulmonary tuberculosis person is often arranged.3, lesions position diminished breath sound, or news and bronchial breathing sound and moist rale.4, sputum smear, concentrated or cultivation, tulase is positive more.5, erythrocyte sedimentation rate speeds.6, tuberculin skin test is strong positive.7, the X line is taken the photograph sheet and is shown the visible TB focus of pulmonary.
Three, Therapeutic Method
Proportioning according to each crude drug takes by weighing medicine of the present invention (daily dose), and oral through filtering medicinal liquid according to the method for boiling medicine usually, each once obeyed on the 1st sooner or later, and 15 is a course of treatment.Foods such as the period in a medicine taboo is pungent, greasy.
Four, efficacy assessment standard
1, cure: transference cure, pulmonary lesions absorbs calcification, and the inspection of expectorant bacterium is turned out cloudy.2, take a turn for the better: doing well,improving, pulmonary lesions partially absorbs.
3, do not heal: symptom and focus no change.
Five, therapeutic outcome statistics
Figure 2012101805865100002DEST_PATH_IMAGE002
Total effective rate=cure rate+improvement rate.

Claims (2)

1. the phthisical Chinese medicine composition of treatment is characterized in that this Chinese medicine composition is made up of following bulk drugs: 10-15 parts of Rhizoma Polygonati Odorati, 10-15 parts of Bulbus Liliies, 10-20 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 15-25 parts of Rhizoma Imperataes, 25-35 parts of Herba Agrimoniaes, 25-35 parts of Herba Houttuyniae, 10-15 parts of Cortex Mori, 5-15 parts of Radix Notoginseng powder, 10-15 parts of the Radixs Stemonae, 10-15 parts of Carapax Trionycis, 1-5 parts in Radix Glycyrrhizae, 10-15 parts of Cortex Moutans.
2. the phthisical Chinese medicine composition of treatment according to claim 1 is characterized in that this Chinese medicine composition is made up of following bulk drugs: 12 parts of Rhizoma Polygonati Odorati, 12 parts of Bulbus Liliies, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Rhizoma Imperataes, 30 parts of Herba Agrimoniaes, 30 parts of Herba Houttuyniae, 12 parts of Cortex Mori, 9 parts of Radix Notoginseng powder, 12 parts of the Radixs Stemonae, 12 parts of Carapax Trionycis, 3 parts in Radix Glycyrrhizae, 12 parts of Cortex Moutans.
CN2012101805865A 2012-06-04 2012-06-04 Traditional Chinese medicine combination for treating tuberculosis Pending CN102671088A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432434A (en) * 2013-08-01 2013-12-11 焦敏 Traditional Chinese medicine composition for treating phthisis
CN103689786A (en) * 2013-12-23 2014-04-02 孙斌 Cigarette for treating toothache caused by external contraction of wind evil
CN104027570A (en) * 2014-05-10 2014-09-10 当涂县科辉商贸有限公司 Health-care effervescent tablet assisting to treat pulmonary tuberculosis and preparation method thereof
CN105963601A (en) * 2016-06-25 2016-09-28 三穗县中医医院 Traditional Chinese medicine formula for curing pulmonary tuberculosis
CN106075226A (en) * 2016-06-25 2016-11-09 三穗县中医医院 One treats phthisical Chinese medicine formula

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1256131A (en) * 1998-10-30 2000-06-14 邓钦文 Chinese herbal medicine for treating pulmonary tuberculosis
CN1424098A (en) * 2002-12-30 2003-06-18 方文理 Medicines for treating pulmonary tuberculosis
CN101249241A (en) * 2008-03-10 2008-08-27 许文成 Medicament for radically treating phthisis and method of preparing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1256131A (en) * 1998-10-30 2000-06-14 邓钦文 Chinese herbal medicine for treating pulmonary tuberculosis
CN1424098A (en) * 2002-12-30 2003-06-18 方文理 Medicines for treating pulmonary tuberculosis
CN101249241A (en) * 2008-03-10 2008-08-27 许文成 Medicament for radically treating phthisis and method of preparing the same

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Title
张廷模: "《临床中药学》", 31 December 2011, 中国中医药出版社, article "三七", pages: 367 *
韩龙蜂,等: "中西医结合治疗肺结核的临床观察", 《湖北中医杂志》, vol. 29, no. 1, 31 December 2007 (2007-12-31), pages 30 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432434A (en) * 2013-08-01 2013-12-11 焦敏 Traditional Chinese medicine composition for treating phthisis
CN103432434B (en) * 2013-08-01 2015-09-23 焦敏 A kind of Chinese medicine composition for the treatment of pulmonary tuberculosis
CN103689786A (en) * 2013-12-23 2014-04-02 孙斌 Cigarette for treating toothache caused by external contraction of wind evil
CN103689786B (en) * 2013-12-23 2015-08-26 赵健 A kind of cigarette being used for the treatment of diseases caused by external factors wind-evil syndrome and having a toothache
CN104027570A (en) * 2014-05-10 2014-09-10 当涂县科辉商贸有限公司 Health-care effervescent tablet assisting to treat pulmonary tuberculosis and preparation method thereof
CN105963601A (en) * 2016-06-25 2016-09-28 三穗县中医医院 Traditional Chinese medicine formula for curing pulmonary tuberculosis
CN106075226A (en) * 2016-06-25 2016-11-09 三穗县中医医院 One treats phthisical Chinese medicine formula
CN105963601B (en) * 2016-06-25 2019-09-17 三穗县中医医院 It is a kind of to treat phthisical Chinese medicine preparation
CN106075226B (en) * 2016-06-25 2019-09-17 三穗县中医医院 It is a kind of to treat phthisical Chinese medicine preparation

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Application publication date: 20120919