CN105213871A - A kind of emergency department bactericidal haemostatic Chinese medicine preparation - Google Patents
A kind of emergency department bactericidal haemostatic Chinese medicine preparation Download PDFInfo
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Abstract
The present invention relates to application in TCM field, particularly disclose a kind of emergency department bactericidal haemostatic Chinese medicine preparation.This kind of emergency department bactericidal haemostatic Chinese medicine preparation, by Radix Notoginseng, Receptaculum Nelumbinis, Ophicalcitum, Pollen Typhae, Radix Toddaliae Asiaticae, catechu, Folium Callicarpae Macrophyllae, Amaranthus spinosus L., Herba Bryophylli Pinnati, Flos Sophorae, Herba Cirsii, Radix Rubiae, Herba Ecliptae, Radix Cirsii Japonici, Rhizoma Imperatae, Radix Sanguisorbae, Herba Agrimoniae, Herba Clinopodii, Radix Polygoni Ciliinerve, Herba Melastomatis dodecandri root, Folium Loropetali, Folium Callicarpae Formosanae and Pollen Pini form according to certain weight proportion mixed preparing.The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer and alleviates condition of illness in time.
Description
(1) technical field
The present invention relates to application in TCM field, particularly a kind of emergency department bactericidal haemostatic Chinese medicine preparation.
(2) background technology
In prior art, the sufferer of emergency treatment section office mostly is the wound class wounded, doctor mainly carries out cardio-pulmonary resuscitation to patient, wound hemostasis process, the wounded shipped from the scene of the accident often hemorrhage larger, wound is comparatively filthy, clear up as carried out not in time and stop blooding and great injury is often caused to the wounded, once wound contamination and occur suppurate, septicemia, tetanus or bacteriological infection, great inconvenience is brought by follow-up treatment, the bactericidal haemostatic medicine of existing emergency department is chemical industry sintetics, it has sterilization thoroughly, the advantage such as to stop blooding quick, but also there is sensitization simultaneously, traumatizing, zest, once patient has anaphylaxis or accelerates the reaction generation of wound deterioration, great injury will be caused to patient.
(3) summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides and a kind ofly prepares emergency department simple, evident in efficacy bactericidal haemostatic Chinese medicine preparation.
The present invention is achieved through the following technical solutions:
A kind of emergency department bactericidal haemostatic Chinese medicine preparation, be made up of the Chinese medicine of following parts by weight:
Radix Notoginseng 12-25 gram, Receptaculum Nelumbinis 11-27 gram, Ophicalcitum 21-23 gram, Pollen Typhae 13-26 gram, Radix Toddaliae Asiaticae 11-23 gram, catechu 10-22 gram, Folium Callicarpae Macrophyllae 11-25 gram, Amaranthus spinosus L. 12-24 gram, Herba Bryophylli Pinnati 11-23 gram, Flos Sophorae 10-22 gram, Herba Cirsii 12-25 gram, Radix Rubiae 11-24 gram, Herba Ecliptae 10-24 gram, Radix Cirsii Japonici 12-23 gram, Rhizoma Imperatae 12-25 gram, Radix Sanguisorbae 13-24 gram, Herba Agrimoniae 12-23 gram, Herba Clinopodii 10-25 gram, Radix Polygoni Ciliinerve 13-22 gram, Herba Melastomatis dodecandri root 11-27 gram, Folium Loropetali 12-23 gram, Folium Callicarpae Formosanae 13-26 gram, Pollen Pini 15-27 gram.
The weight proportion of its preferred each raw material is:
Radix Notoginseng 12 grams, Receptaculum Nelumbinis 11 grams, Ophicalcitum 21 grams, Pollen Typhae 13 grams, Radix Toddaliae Asiaticae 11 grams, 10 grams, catechu, Folium Callicarpae Macrophyllae 11 grams, Amaranthus spinosus L. 12 grams, Herba Bryophylli Pinnati 11 grams, 10 grams, Flos Sophorae, Herba Cirsii 12 grams, 11 grams, Radix Rubiae, Herba Ecliptae 10 grams, Radix Cirsii Japonici 12 grams, Rhizoma Imperatae 12 grams, Radix Sanguisorbae 13 grams, Herba Agrimoniae 12 grams, Herba Clinopodii 10 grams, Radix Polygoni Ciliinerve 13 grams, Herba Melastomatis dodecandri root 11 grams, Folium Loropetali 12 grams, Folium Callicarpae Formosanae 13 grams, Pollen Pini 15 grams.
Chinese medicine of the present invention is unguentum or water preparation, and after being cleaned up by various raw material, play powder mixing, make unguentum or water preparation, paste application is in skin surface, and water preparation is sprayed on skin surface.
Wherein the pharmaceutical characteristic of each raw material is:
Radix Notoginseng: warm in nature, sweet in the mouth, micro-hardship.Return Liver Channel, stomach warp.Dissipating blood stasis hemostasis, subduing swelling and relieving pain.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.With controlling spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.Animal experiment shows, ginsenoside Rg's class has excitation to nervus centralis, Rb class then has inhibitory action, and Radix Notoginseng total arasaponins can suppress platelet aggregation, Radix Notoginseng extract has heart tonifying, blood pressure lowering, protects the liver, antiinflammatory, reduction blood cholesterol, immunomodulating and antivirus action.It is sayed in total face, blood and hemopoietic system is had to the effects such as hemostasis, antiplatelet aggregation and thrombolytic, haemolysis, hemopoietic; Cardiovascular system is had to arrhythmia, atherosclerosis, anoxia enduring and shock, improves the effects such as cerebral ischemia; To nervous system, there is the effect such as central nerve inhibition, analgesia; Improving immunocompetence, liver function protecting, antitumor, slow down aging, blood sugar lowering, antiinflammatory, Auto-regulator metabolism, growth promoting effects; Toxicity is lower, and long-term prescription is substantially without side reaction.
Receptaculum Nelumbinis: warm in nature is bitter in the mouth, puckery.Return Liver Channel.Removing stasis to stop bleeding.The stasis-resolving hemostatic of classifying under belonging to hemorrhage.For metrorrhagia, hematuria, bleeding hemorrhoids, postpartum stagnation, lochiorrhea.
Ophicalcitum: property is put down, sour in the mouth, puckery.Return Liver Channel, removing stasis to stop bleeding.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.With controlling spitting of blood, spit blood, traumatic hemorrhage, falls and flutters the pain of injury.Main containing calcium carbonate.Still containing hydrous magnesium silicate and 20 multiple elements such as a small amount of ferrum, aluminum and trace zinc, manganese, copper, cobalt, nickel, chromium, lead.Its 20% suspension has obvious anticonvulsant action to mouse stomach to the convulsions that dimefline brings out; And have blood coagulation and anastalsis.
Pollen Typhae: property is put down, sweet in the mouth.Return Liver Channel, heart channel.Hemostasis, Huayu Tonglin.Belong to the stasis-resolving hemostatic under hemorrhage classification.With controlling various hemorrhage, the stagnant pain disease of the stasis of blood, chest pain as stagnant in the stasis of blood, gastralgia and puerperal the stasis of blood pain, dysmenorrhea; Stranguria with blood, dysentery etc.Containing compounds such as volatile oil, polysaccharide, acids and alkanes.This product has blood fat reducing and study of anti-atherogenic effect; And have antiinflammatory action.
Radix Toddaliae Asiaticae: warm in nature, acrid in the mouth, hardship.Return spleen channel, stomach warp.Wind-expelling pain-stopping, dissipating blood stasis stop blooding.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification., dysmenorrhea, amenorrhea, amebic dysentery hemorrhage with dispelling the wind and dampness pathogens arthralgia pain, stomachache, traumatic injury, haematemesis, epistaxis, knife injury, toothache, malaria.Containing chelerythrine, dihydrochelerythrine etc.Experiment shows, this product biology total alkali has antiinflammatory action, can suppress dimethylbenzene induced mice ear swelling, suppresses the foot swelling of agar induced mice, suppresses leukoplania caused by sodium carboxymethyl cellulose; There is analgesic activity simultaneously, the number of times of glacial acetic acid induced mice writhing response can be reduced.
Catechu: cold nature is bitter in the mouth, puckery.Return lung meridian, heart channel.Removing dampness, granulation promoting, sore, hemostasis.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.With controlling ulcer being unable to heal, eczema, aphtha, falling and flutter the pain of injury, traumatic hemorrhage.Pharmacological evaluation shows, aqueous solution can suppress the wriggling of duodenum in rabbit and small intestinal, and can promote the retrostalsis of caecum, and has anti-diarrhea effect.Water decoction all has inhibitory action to staphylococcus aureus, diphtheria corynebacterium, Bacillus proteus, shigella flexneri and Bacillus typhi, also has inhibitory action to Common Pathogenic dermatophytes.
Folium Callicarpae Macrophyllae: property is put down, acrid in the mouth, hardship.Return Liver Channel, lung meridian, stomach warp.Dissipating blood stasis stops blooding, reducing swelling and alleviating pain.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.For epistaxis, spitting of blood, spits blood, has blood in stool, traumatic hemorrhage, tumbling and swelling.
Amaranthus spinosus L.: sweet, light, cool.1. heat-clearing and toxic substances removing.2. astringing to arrest bleeding dysentery.3. antibacterial, antiinflammatory, detumescence.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis.For dysentery, enteritis, taste-blindness rate is hemorrhage, hemorrhoidal hemorrhage; Venom is controlled in external, skin eczema, furuncle and phyma pus infections.
Herba Bryophylli Pinnati: cold in nature is the micro-acid of taste, puckery.Return lung meridian, kidney channel.Removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.The blood-cooling hemostatic of classifying under belonging to hemorrhage.With controlling laryngopharynx swelling and pain, hot stomachache, diarrhea of heat type hematodiarrhoea, hemoptysis, haematemesis, acute catarrhal conjunctivitis, otitis media, carbuncle furunculosis, acute mastitis, burn due to hot liquid or fire, traumatic hemorrhage etc.Leaf containing cis-aconitic, ascorbic acid, to bean fragrant element, ferulic acid, syringic acid, caffeic acid, P-hydroxybenzoic acid and other organic acid etc.To multiple Gram-positive and gram negative bacteria, there is broad-spectrum bactericidal action, comprise and clinically isolatedly multiple there is drug-fast antibacterial.
Flos Sophorae: cold nature, bitter in the mouth.Return Liver Channel, large intestine channel.Cooling blood for hemostasis, purging liver-fire.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.With treating hematochezia, hemorrhoidal bleeding, dysentery, metrorrhagia, haematemesis, epistaxis, liver-heat conjunctival congestion, have a headache dizzy.Containing rutin (rutin) 10% ~ 28%.The highest with content in alabastrum, after open, content reduces.Another containing compositions such as triterpene saponin, glucose, glucuronic acids.Pharmacological research shows, contained rutin and aglycon quercetin thereof can keep the normal tension of blood capillary, reduce its permeability, and the blood capillary hemorrhage because fragility increases can be made to recover normal elasticity.Quercetin can expand coronary vasodilator, improves myocardial circulation, strengthens contractility and the output of the heart; And reduce heart rate.There are antiinflammatory, spasmolytic and antiulcer action, and all have inhibitory action to antibacterial, virus and fungus.
Herba Cirsii: cool in nature, sweet in the mouth, hardship.GUIXIN warp, Liver Channel.Cooling blood for hemostasis, removing blood stasis to reduce swelling.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.With controlling haematemesis, epistaxis, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, jaundice, carbuncle sore tumefacting virus etc.There is anastalsis.PARA FORMALDEHYDE PRILLS(91,95) arthritis has antiinflammation to a certain degree; Also has calm, antibacterial and choleretic effect.Containing choline, saponin, Catecholamine matter, and the reaction of aobvious alkaloid saponin.Water decoction has the effect of direct sympathomimetic, the rat of destroying spinal cord after anesthesia is had to the boosting of norepinephrine sample; All excitation is had to extrasomatic rabbit heart and toad heart.
Radix Rubiae: bitter, cold.Return Liver Channel.There is cooling blood for hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow.Cure mainly heat in blood and tell nosebleed, metrostaxis, blood stasis amenorrhea, traumatic injury, rheumatic arthralgia, promoting the circulation of blood is stopped blooding, and relieving cough and resolving phlegm is relievingd asthma anti-inflammation.Herba Ecliptae: cold in nature, sweet in the mouth, acid.Return kidney channel, Liver Channel.Nourishing the liver and kidney, cooling blood for hemostasis.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.Use treating the liver deficiency of the kidney yin, odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.Herb contains Saponin 1.32%, nicotine about 0.08%, tannin, vitamin A, ecliptine, multiple thiophene compound, wedelolactone, demethylwedelolactone.Demethylwedelolactone-7-glycoside, aerial parts Petroleum ether extraction part is containing stigmasterol, plant sterol A and β-balsam; Still containing luteolin-7-O-glycoside, plant sterol A glycoside and a kind of triterpenic acid glycoside in ethanol extraction.
Radix Cirsii Japonici: cool in nature, sweet in the mouth, hardship.GUIXIN warp, Liver Channel.Cooling blood for hemostasis, removing blood stasis to reduce swelling.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.External fresh goods is appropriate, smashes deposited.With controlling epistaxis, haematemesis, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus.
Rhizoma Imperatae: fresh leaf contains 6-methoxyl group pectolinarin, 6,4 ' one dimethoxy baicalin-7-rhamnoglucoside.And containing Herba Linariae Vulgaris element, 5,7-dihydroxy-6,4 ' one dimethoxy flavone.It is reported, herb shows alkaloid and volatile oil reaction.There is blood pressure lowering, the effect such as antibacterial, have inhibitory action to meningococcus, diphtheria corynebacterium.
Radix Sanguisorbae: cold nature, bitter in the mouth, acid, puckery.Return Liver Channel, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.Suitable amount used externally, grinds coating affected part into powder.With treating hematochezia, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Containing Radix Sanguisorbae glycosides I, Radix Sanguisorbae glycosides II, aglycon 19-Alpha-hydroxy ursolic acid.Another containing sanguisorbin A, sanguisorbin B, sanguisorbin E, aglycon ursolic acid, and the composition such as catechin.Pharmacological research, has anastalsis, and wound fluid can be made to reduce, and infection, is conducive to wound tissue healing.In addition, the effect such as blood pressure lowering and emesis is still had.
Herba Agrimoniae: property is put down, bitter in the mouth, puckery.GUIXIN warp, Liver Channel.Astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.Belong to the astringent hemostatic of hemorrhage subordinate classification.Suitable amount used externally.With controlling spitting of blood, haematemesis, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.Containing agrimonine, red crowned crane lactone, tannin, sterol, organic acid, phenolic constituent, saponin, flavonoid glycoside etc.Herba Agrimoniae have hemostasis, adjustment heart rate, increases cell resistance power, reduces the effect such as blood glucose and antiinflammatory; Hibernaculum is containing phenolic substance crane bud phenol, and hibernaculum and root have stronger expelling tenia effect, all have inhibitory action to staphylococcus aureus, escherichia coli, bacillus pyocyaneus, shigella flexneri, Bacillus typhi.
Herba Clinopodii: cool in nature is bitter in the mouth, puckery.Return Liver Channel.Astringing to arrest bleeding.Belong to the astringent hemostatic of hemorrhage subordinate classification.Treatment metrorrhagia, hematuria, epistaxis, gingival hemorrhage, wound hemorrhage.
Radix Polygoni Ciliinerve: cold nature is mildly bitter flavor, puckery.Return stomach warp, spleen channel, urinary bladder channel, large intestine channel.Hemostasis, invigorates blood circulation, nourishes blood, dysentery relieving, convergence pain relieving.Belong to the astringent hemostatic of hemorrhage subordinate classification.Clinical being usually used in treats haematemesis, spitting of blood, metrorrhagia, postpartum hemorrhage, hematuria, traumatic hemorrhage, anemia, dysentery, diarrhoea, joint aches, venom.Tuber, containing condensed tannin, still contains phenols, saponin, protein, saccharide, phlegmatic temperament etc.Pharmacological evaluation shows: 40% ethanol extract and the decocting liquid of Radix Polygoni Ciliinerve have antibacterial action.Significantly can shorten clotting time and the bleeding time of rabbit.
Herba Melastomatis dodecandri root: property is put down, the micro-acid of taste, puckery.Return lung meridian, spleen channel, Liver Channel.Promoting blood circulation to remove obstruction in the collateral, astringing to arrest bleeding.Belong to the astringent hemostatic under hemorrhage classification.。With dispelling the wind and dampness pathogens arthralgia pain, lumbago and skelalgia, puerperal abdonimal pain, bleeding not during menses, traumatic hemorrhage.
Folium Loropetali: cool in nature is bitter in the mouth, puckery.Return Liver Channel, stomach warp, large intestine channel.Heat-clearing and toxic substances removing, convergence, hemostasis.Belong to the astringent hemostatic of hemorrhage subordinate classification.With control burn or scald, traumatic hemorrhage, haematemesis, metrorrhagia, diarrhoea.Containing reducing sugar, glycoside and phenolic substance.There is antibacterial and uterine contraction effect, have impact to cardiovascular.The tannic acid of this product and derivant thereof have coagulation sedimentation effect to protein or serum, can shrink blood capillary and promote blood coagulation.
Folium Callicarpae Formosanae: cool in nature is bitter in the mouth, puckery.Return Liver Channel, lung meridian, stomach warp.Astringing to arrest bleeding, heat-clearing and toxic substances removing.Belong to that hemorrhage astringing to arrest bleeding is medicinal controls various hemorrhage caused by heat in blood, especially better with digestive tract, respiratory tract hemorrhage effect; External treatment skin sore, venom; Pyretic toxicity laryngopharynx swelling and pain, conjunctival congestion and swelling pain etc.This product is cool in nature, the careful clothes of deficient cold type bleeding patients.Containing condensed tannin, flavonoid, resinene, saccharide, hydroxy compounds and magnesium, calcium and micro-iron salt etc.Can platelet be increased, shorten hemorrhage, thrombinogen, clot retration time, frog mesenteric is shunk; Inhibitory action is had to escherichia coli, bacterium flexneri, staphylococcus aureus, streptococcus etc.
Pollen Pini: warm in nature, sweet in the mouth.Return Liver Channel, spleen channel.Dampness, astringing to arrest bleeding.The astringent hemostatic of classifying under belonging to hemorrhage.External is dry mixes or dresses.Consumption 3 ~ 5 grams, is taken after mixing with liquid or infusing drugs in wine drink.With chickenpox of harnessing the Yellow River, skin eczema, erosion, baby diaper dermatitis, traumatic hemorrhage.There are antiviral and convergence, anastalsis.External application haemostatic effect is good.Separately have and increase endurance, effect to resisting fatigue.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer and alleviates condition of illness in time.
(4) detailed description of the invention
Embodiment 1:
Get Radix Notoginseng 12 grams, Receptaculum Nelumbinis 11 grams, Ophicalcitum 21 grams, Pollen Typhae 13 grams, Radix Toddaliae Asiaticae 11 grams, 10 grams, catechu, Folium Callicarpae Macrophyllae 11 grams, Amaranthus spinosus L. 12 grams, Herba Bryophylli Pinnati 11 grams, 10 grams, Flos Sophorae, Herba Cirsii 12 grams, 11 grams, Radix Rubiae, Herba Ecliptae 10 grams, Radix Cirsii Japonici 12 grams, Rhizoma Imperatae 12 grams, Radix Sanguisorbae 13 grams, Herba Agrimoniae 12 grams, Herba Clinopodii 10 grams, Radix Polygoni Ciliinerve 13 grams, Herba Melastomatis dodecandri root 11 grams, Folium Loropetali 12 grams, Folium Callicarpae Formosanae 13 grams, Pollen Pini 15 grams, cleans up above-mentioned raw materials, plays powder mixing, makes unguentum or water preparation.
Usage and dosage: unguentum sticks on wound, and water preparation is sprayed on skin surface.
Embodiment 2:
Get Radix Notoginseng 25 grams, Receptaculum Nelumbinis 27 grams, Ophicalcitum 23 grams, Pollen Typhae 26 grams, Radix Toddaliae Asiaticae 23 grams, 22 grams, catechu, Folium Callicarpae Macrophyllae 25 grams, Amaranthus spinosus L. 24 grams, Herba Bryophylli Pinnati 23 grams, 22 grams, Flos Sophorae, Herba Cirsii 25 grams, 24 grams, Radix Rubiae, Herba Ecliptae 24 grams, Radix Cirsii Japonici 23 grams, Rhizoma Imperatae 25 grams, Radix Sanguisorbae 24 grams, Herba Agrimoniae 23 grams, Herba Clinopodii 25 grams, Radix Polygoni Ciliinerve 22 grams, Herba Melastomatis dodecandri root 27 grams, Folium Loropetali 23 grams, Folium Callicarpae Formosanae 26 grams, Pollen Pini 27 grams, cleans up above-mentioned raw materials, plays powder mixing, makes unguentum or water preparation.
Usage and dosage: unguentum sticks on wound, and water preparation is sprayed on skin surface.
Embodiment 3:
Get Radix Notoginseng 18 grams, Receptaculum Nelumbinis 22 grams, Ophicalcitum 22 grams, Pollen Typhae 22 grams, Radix Toddaliae Asiaticae 18 grams, 17 grams, catechu, Folium Callicarpae Macrophyllae 21 grams, Amaranthus spinosus L. 18 grams, Herba Bryophylli Pinnati 17 grams, 16 grams, Flos Sophorae, Herba Cirsii 21 grams, 20 grams, Radix Rubiae, Herba Ecliptae 22 grams, Radix Cirsii Japonici 18 grams, Rhizoma Imperatae 21 grams, Radix Sanguisorbae 19 grams, Herba Agrimoniae 17 grams, Herba Clinopodii 18 grams, Radix Polygoni Ciliinerve 16 grams, Herba Melastomatis dodecandri root 23 grams, Folium Loropetali 17 grams, Folium Callicarpae Formosanae 18 grams, Pollen Pini 21 grams, cleans up above-mentioned raw materials, plays powder mixing, makes unguentum or water preparation.
Usage and dosage: unguentum sticks on wound, and water preparation is sprayed on skin surface.
Clinical experiment:
1, experimental strain: staphylococcus aureus, bacillus pyocyaneus, escherichia coli.
2, bacterium culture medium: nutrient agar and nutrient broth medium.
3, bacteriostatic experiment divides experimental group and matched group, and experimental group is germ killing drugs of the present invention, and matched group selects sodium chlorate disinfectant solution.
4, specific experiment step:
(1) bacterium liquid is prepared: be inoculated on two agar culture mediums respectively by above-mentioned two groups of strains, cultivate 24 hours at 37 DEG C, therefrom picking colonies typical is inoculated in two fresh nutrient broth mediums respectively respectively, under synthermal, cultivate 18 hours, for subsequent use;
(2) get germ killing drugs of the present invention and each 100ml of sodium chlorate disinfectant solution respectively, be placed in cut-back tank respectively, 20 times are diluted respectively to it, upper two kinds of diluent solution are split in two containers respectively, under being placed in aseptic condition, for subsequent use;
(3) experimental strain that above-mentioned steps (1) is supported 18 hours through nutrition broth cultivation is diluted 100 times respectively with aseptic nutrient broth, often kind of strain is sub-packed in two culture dishs, respectively labelling matched group and experimental group;
(4) by the dilute solution of the disinfectant solution of the present invention of above-mentioned steps (2) gained instillation experimental group culture dish, sodium chlorate disinfectant solution dilute solution instillation matched group culture dish.
5, laboratory observation is measured:
| Strain | Experimental group | Matched group | Bacterium colony revolution mark |
| Staphylococcus aureus | 2.5％ | 25.9％ | - |
| Bacillus pyocyaneus | 3.2％ | 32％ | - |
| Escherichia coli | 1.3％ | 27.3％ | - |
Observe above-mentioned experiment and measure strain revolution mark, concrete outcome is as above shown.
6, after observation is measured, leave standstill three days under above-mentioned culture dish being all placed in aseptic condition, tracing observation finds, matched group bacterium colony continues breeding, and experimental group bacterium colony is unchanged.
7, experimental result:
The sterilizing ability of experimental group much larger than the sterilizing ability of matched group, and can suppress strain to continue breeding.
Claims (3)
1. emergency department's bactericidal haemostatic Chinese medicine preparation, it is characterized by, be made up of the Chinese medicine of following parts by weight: Radix Notoginseng 12-25 gram, Receptaculum Nelumbinis 11-27 gram, Ophicalcitum 21-23 gram, Pollen Typhae 13-26 gram, Radix Toddaliae Asiaticae 11-23 gram, catechu 10-22 gram, Folium Callicarpae Macrophyllae 11-25 gram, Amaranthus spinosus L. 12-24 gram, Herba Bryophylli Pinnati 11-23 gram, Flos Sophorae 10-22 gram, Herba Cirsii 12-25 gram, Radix Rubiae 11-24 gram, Herba Ecliptae 10-24 gram, Radix Cirsii Japonici 12-23 gram, Rhizoma Imperatae 12-25 gram, Radix Sanguisorbae 13-24 gram, Herba Agrimoniae 12-23 gram, Herba Clinopodii 10-25 gram, Radix Polygoni Ciliinerve 13-22 gram, Herba Melastomatis dodecandri root 11-27 gram, Folium Loropetali 12-23 gram, Folium Callicarpae Formosanae 13-26 gram, Pollen Pini 15-27 gram.
2. emergency department according to claim 1 bactericidal haemostatic Chinese medicine preparation, is characterized by, and is made up of the Chinese medicine of following parts by weight: Radix Notoginseng 12 grams, Receptaculum Nelumbinis 11 grams, Ophicalcitum 21 grams, Pollen Typhae 13 grams, Radix Toddaliae Asiaticae 11 grams, 10 grams, catechu, Folium Callicarpae Macrophyllae 11 grams, Amaranthus spinosus L. 12 grams, Herba Bryophylli Pinnati 11 grams, 10 grams, Flos Sophorae, Herba Cirsii 12 grams, 11 grams, Radix Rubiae, Herba Ecliptae 10 grams, Radix Cirsii Japonici 12 grams, Rhizoma Imperatae 12 grams, Radix Sanguisorbae 13 grams, Herba Agrimoniae 12 grams, Herba Clinopodii 10 grams, Radix Polygoni Ciliinerve 13 grams, Herba Melastomatis dodecandri root 11 grams, Folium Loropetali 12 grams, Folium Callicarpae Formosanae 13 grams, Pollen Pini 15 grams.
3. emergency department according to claim 1 and 2 bactericidal haemostatic Chinese medicine preparation, is characterized in that: described Chinese medicine is unguentum or water preparation.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266717A (en) * | 2016-09-24 | 2017-01-04 | 徐静 | A kind of emergency department nursing efficient quick-acting haemostatic powder patch and preparation method thereof |
| CN106880868A (en) * | 2017-02-13 | 2017-06-23 | 安徽宇宁果胶股份有限公司 | A kind of haemostatic sprays |
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