CN101642552B - Plaster for treating chronic diarrhea - Google Patents
Plaster for treating chronic diarrhea Download PDFInfo
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- CN101642552B CN101642552B CN2009101169463A CN200910116946A CN101642552B CN 101642552 B CN101642552 B CN 101642552B CN 2009101169463 A CN2009101169463 A CN 2009101169463A CN 200910116946 A CN200910116946 A CN 200910116946A CN 101642552 B CN101642552 B CN 101642552B
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- chronic diarrhea
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- ointment
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Abstract
The invention relates to a plaster for treating chronic diarrhea, which is prepared from the following raw materials: sesame oil, yellow lead, radix aconiti praeparata, white atractylodes rhizome, tuckahoe, white peony root, ginger, yam, semen coicis, costustoot, azone and nano ceramic powder. The preparation method comprises the following contents: preparing an ointment substrate by the sesame oil and the yellow lead; after decocting other medicine materials with water, taking decoction, removing residues, concentrating the obtained medicine decoction and obtaining a medicine material extract; after dissolving the ointment substrate, adding the medicine material extract, the nano ceramic powder and the azone to obtain the ointment; and spreading the ointment on a backing material so as to obtain the plaster. The plaster for treating chronic diarrhea, which is provided by the invention, has the characteristics of accurate application, strong permeability and high content of effective components and has better curative effect for treating chronic diarrhea.
Description
Technical field
The present invention relates to a kind of plaster that is used for the treatment of chronic diarrhea.
Background technology
At present, adopt oral drugs or transfusion to treat usually to chronic diarrhea in clinical, oral medicine stimulates bigger to gastrointestinal, and the patient is difficult to stand, and transfusion then can have in various degree damage to liver, kidney.The result of use of the more existing plaster that is used for the treatment of chronic diarrhea is also not ideal enough, and its main cause is: material choice inadequately accurately, the active constituent content permeability low, plaster in the plaster is not good.
Summary of the invention
The object of the present invention is to provide a kind of plaster that is used for the treatment of chronic diarrhea, accurate and effective component content height of these plaster materials and good penetrability.
For achieving the above object, adopt following scheme:
The present invention the plaster that is used for the treatment of chronic diarrhea that provides is provided is made by the following dosage proportion raw material: Oleum sesami 1500～1560 grams, Plumbum preparatium 1050～1100 grams, Radix Aconiti Lateralis Preparata 18～30 grams, the Rhizoma Atractylodis Macrocephalae 30～40 grams, Poria 40～50 grams, the Radix Paeoniae Alba 20～30 grams, Rhizoma Zingiberis Recens 30～40 grams, Rhizoma Dioscoreae 45～55 grams, Semen Coicis 50～65 grams, the Radix Aucklandiae 20～25 grams, 10～20 milliliters of azones, nano-ceramic powder 15～25 grams.
The preparation method of plaster that is used for chronic diarrhea provided by the invention is: Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, after treating that Plumbum preparatium and Oleum sesami are combined to paste, cream is poured in the cold water slowly, make cream in water, be cooled to band shape, after treating that cream condenses, taking-up was soaked in water 7 after pinching pressure, during, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate; After Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Rhizoma Dioscoreae, Semen Coicis, the Radix Aucklandiae be soaked in water 20～30 hours, water decocted 2～3 times, and each back extracting juice that decocts removes slag, and then the medicine juice that obtains is merged the back and concentrates, and obtains spice extractum; With ointment substrate heating and melting, add spice extractum, nano-ceramic powder, azone then and fully mix, obtain ointment; The cream beach of getting it filled is being mounted on the backing material, treat that ointment is cooled to solid after, both plaster.
The present invention is a material medicine that to be selected pointedly have curative effect to chronic diarrhea in prescription, and the 2nd, selected azone, nano-ceramic powder for use.The effect of azone, nano-ceramic powder is respectively: azone is a kind of cutaneous permeable agent, and it is added in the pharmaceutical formulation, can improve the effect that drug transdermal absorbs; Nano-ceramic powder can absorb outside energy, promotes the absorption of human body to medicine.
In the preparation method of plaster that is used for the treatment of chronic diarrhea provided by the invention,, can guarantee content of effective in the plaster, and traditional way with spice " fried endure withered " can be destroyed the many effective ingredient in the spice with the spice water boiling and extraction.
As seen the plaster that is used for the treatment of chronic diarrhea provided by the invention has the advantages that medication is accurate, penetration is strong, active constituent content is high, when it uses, by absorbing outside energy and human body heat energy, has stronger penetrating power, can infiltrate skin and subcutaneous tissue, produce resonant absorption effects, play microcirculation improvement and improve tissue metabolism's nutrition with hydrone in the human body cell, promote the effect of the absorption of inflammation exudate, and reach the effect of stasis-dispelling and pain-killing, QI invigorating Kaiyang, invigorating the spleen to arrest diarrhea.It has curative effect preferably to the treatment chronic diarrhea.
The specific embodiment
Further specify the present invention below in conjunction with embodiment.
Embodiment
In the present embodiment, the concrete consumption proportion that is used for the treatment of used each raw material of plaster of chronic diarrhea is: Oleum sesami 1550 grams, Plumbum preparatium 1060 grams, Radix Aconiti Lateralis Preparata 24 grams, the Rhizoma Atractylodis Macrocephalae 35 grams, Poria 45 grams, the Radix Paeoniae Alba 25 grams, Rhizoma Zingiberis Recens 35 grams, Rhizoma Dioscoreae 50 grams, Semen Coicis 58 grams, the Radix Aucklandiae 23 grams, 15 milliliters of azones, nano-ceramic powder 20 grams.
The preparation method of the plaster that is used for the treatment of chronic diarrhea that present embodiment provides has following concrete steps:
1, Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, after treating that Plumbum preparatium and Oleum sesami are combined to paste, cream is poured in the cold water slowly, make cream in water, be cooled to band shape, after treating that cream condenses, taking-up was soaked in water 7 after pinching pressure, during, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate;
2, Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Rhizoma Dioscoreae, Semen Coicis, the Radix Aucklandiae were soaked in water 20～30 hours after, water decocts 2～3 times, amount of water is good for being higher than spice 2～3cm, decoct to liquid medicine boiling back at every turn, decocted 40～50 minutes again, each back extracting juice that decocts removes slag, then the medicine juice that obtains is merged the back and concentrate,, obtain spice extractum to becoming to hang the flag shape with the sticking medicine juice that goes of Glass rod;
3, with ointment substrate heating and melting, be cooled to 65～75 ℃, add spice extractum, nano-ceramic powder, azone then and fully mix, obtain ointment; Cream 9～10 gram beach of getting it filled are being mounted on the backing material, mount the backing material and adopt the medical no yarn adhesive plaster of desensitization, treat that ointment is cooled to solid after, both one force on;
4, the plaster that makes is packed into seal in the aluminium plastic bag.
Above-described azone, nano-ceramic powder are the commercially available prod, and azone is the standardized product that is used for pharmaceuticals industry.
In addition, this ointment should be contained in the container of sealing, places drying, the keeping of shady and cool place.
For better checking curative effect of the present invention, below contrast test by curative effect group, matched group, further specify the beneficial effect of plaster treatment dysmenorrhea provided by the invention:
1 grouping and Therapeutic Method
1.1 grouping successively is divided into treatment group and matched group with the patient at random by consultation time, 65 examples are organized in treatment, matched group 62 examples;
1.2 the treatment group uses plaster provided by the invention that the chronic diarrhea patient is treated;
1.3 matched group uses conventional chemical medicine or Chinese patent medicine (as the stupid second piperidines of compound recipe, bismuth subcarbonate, stable, Berberine Tablet, Xianglian Wan etc.) that chronic diarrhea is suffered from the patient and treats;
1.4 the course of treatment, treatment group and matched group were a course of treatment in equal 10 days;
1.5 using method is affixed on umbilical part (stretch fault cave) with plaster provided by the invention after with little bakingization to treatment group patient, paste every day one, avoids cold and uncooked food during the treatment, pungent.
The related data of 2 treatment groups and matched group
2.1 sex distributes, and sees Table one:
Table one
| Group | The example number | The man | The woman |
| The treatment group | 70 | 45 | 25 |
| Matched group | 68 | 41 | 27 |
2.2 age distribution sees Table two
Table two
| Group | The example number | Below 40 years old | 41～60 years old | More than 60 years old |
| The treatment group | 70 | 23 | 38 | 9 |
| Matched group | 68 | 21 | 36 | 11 |
2.3 course of disease situation sees Table three
| Group | The example number | Below 2 years | 3～5 years | 6～10 years | 11～15 years |
| The treatment group | 70 | 8 | 32 | 26 | 4 |
| Matched group | 68 | 5 | 36 | 23 | 4 |
3 efficacy assessment standards
3.1 produce effects, patient's abdominal distention pain disappears or alleviates, and it is normal that stool recovers;
3.2 take a turn for the better, patient's abdominal distention pain relief, times of defecation obviously reduce before the treatment;
3.3 invalid, patient's abdominal distention pain symptom does not have obviously and alleviates, times of defecation is still more.
4 result of the tests (after 2 courses of treatment) see Table four
Table four
| Group | The example number | Produce effects | Take a turn for the better | Invalid | Total effective rate |
| The treatment group | 70 | 23 | 44 | 3 | 95.71％ |
| Matched group | 68 | 19 | 41 | 8 | 88.24％ |
By above contrast test and result as can be seen, plaster provided by the invention has significant curative effect to the TREATMENT OF DYSMENORRHOEA chronic diarrhea.
Claims (3)
1. the plaster that is used for the treatment of chronic diarrhea is characterized in that it is made by the following dosage proportion raw material: Oleum sesami 1500～1560 grams, Plumbum preparatium 1050～1100 grams, Radix Aconiti Lateralis Preparata 18～30 grams, the Rhizoma Atractylodis Macrocephalae 30～40 grams, Poria 40～50 grams, the Radix Paeoniae Alba 20～30 grams, Rhizoma Zingiberis Recens 30～40 grams, Rhizoma Dioscoreae 45～55 grams, Semen Coicis 50～65 grams, the Radix Aucklandiae 20～25 grams, 10～20 milliliters of azones, nano-ceramic powder 15～25 grams.
2. the plaster that is used for the treatment of chronic diarrhea according to claim 1 is characterized in that the consumption proportion of each raw material is: Oleum sesami 1550 grams, Plumbum preparatium 1060 grams, Radix Aconiti Lateralis Preparata 24 grams, the Rhizoma Atractylodis Macrocephalae 35 grams, Poria 45 grams, the Radix Paeoniae Alba 25 grams, Rhizoma Zingiberis Recens 35 grams, Rhizoma Dioscoreae 50 grams, Semen Coicis 58 grams, the Radix Aucklandiae 23 grams, 15 milliliters of azones, nano-ceramic powder 20 grams.
3. described preparation method that is used for the treatment of the plaster of chronic diarrhea of claim 1, it is characterized in that finishing by following steps: Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, treat that Plumbum preparatium and Oleum sesami are combined to paste after, slowly pour into cream in the cold water, make cream in water, be cooled to band shape, treat that cream condenses after, take out and to be soaked in water 7 after pinching pressure, during this time, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate; After Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Rhizoma Dioscoreae, Semen Coicis, the Radix Aucklandiae be soaked in water 20～30 hours, water decocted 2～3 times, and each back extracting juice that decocts removes slag, and then the medicine juice that obtains is merged the back and concentrates, and obtains spice extractum; With ointment substrate heating and melting, add spice extractum, nano-ceramic powder, azone then and fully mix, obtain ointment; The cream beach of getting it filled is being mounted on the backing material, treat that ointment is cooled to solid after, both plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101169463A CN101642552B (en) | 2009-05-31 | 2009-05-31 | Plaster for treating chronic diarrhea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101169463A CN101642552B (en) | 2009-05-31 | 2009-05-31 | Plaster for treating chronic diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101642552A CN101642552A (en) | 2010-02-10 |
| CN101642552B true CN101642552B (en) | 2011-12-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101169463A Expired - Fee Related CN101642552B (en) | 2009-05-31 | 2009-05-31 | Plaster for treating chronic diarrhea |
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| Country | Link |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104127756A (en) * | 2014-06-27 | 2014-11-05 | 郑尧基 | Spleen invigorating anti-diarrheal paste |
| CN111789933A (en) * | 2020-07-24 | 2020-10-20 | 武汉坤元科技有限公司 | Formula and preparation method of navel patch for assisting sleep and promoting gastrointestinal function recovery |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1772081A (en) * | 2005-11-07 | 2006-05-17 | 惠州九惠制药厂 | Diarrhea treating chinese medicine composition |
| CN101129965A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating chronic schistosomiasis diarrhea |
-
2009
- 2009-05-31 CN CN2009101169463A patent/CN101642552B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1772081A (en) * | 2005-11-07 | 2006-05-17 | 惠州九惠制药厂 | Diarrhea treating chinese medicine composition |
| CN101129965A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating chronic schistosomiasis diarrhea |
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| Publication number | Publication date |
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| CN101642552A (en) | 2010-02-10 |
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Granted publication date: 20111214 Termination date: 20120531 |