CN101642551A

CN101642551A - Plaster for treating lumbago and scelalgia

Info

Publication number: CN101642551A
Application number: CN200910116945A
Authority: CN
Inventors: 李跃
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-05-31
Filing date: 2009-05-31
Publication date: 2010-02-10

Abstract

The invention relates to a plaster for treating lumbago and scelalgia, which is prepared from the following raw materials: sesame oil, yellow lead, speranskia tuberculata, strychnos, cassia twig, capsicum, long pepper, radix gentiana macrophylla, pubescent angelica root, dried ginger, centipede, borneol, datura flower, ovientvine, zedoary, corydalis tuber, black-tail snake, azone and nano ceramicpowder. The preparation method comprises the following contents: preparing an ointment substrate by the sesame oil and the yellow lead; grinding the centipede and the borneol into powder which is sieved by a sieve of 110 meshes and obtaining medicine material powder; after decocting other medicine materials with water, taking decoction, removing residues, concentrating the obtained medicine decoction and obtaining a medicine material extract; after dissolving the ointment substrate, adding the medicine material extract, the medicine material powder, the nano ceramic powder and the azone to obtain the ointment; and spreading the ointment on a backing material so as to obtain the plaster. The plaster for treating the lumbago and the scelalgia, which is provided by the invention, has the characteristics of accurate application, strong permeability and high content of effective components and has better curative effect for treating the lumbago and the scelalgia.

Description

The plaster that is used for the treatment of lumbago and skelalgia

Technical field

The present invention relates to a kind of plaster that is used for the treatment of lumbago and skelalgia.

Background technology

At present, adopt massage, massage or oral drugs or transfusion to treat usually to lumbago and skelalgia in clinical, oral medicine stimulates bigger to gastrointestinal, and the patient is difficult to stand, and transfusion then can have in various degree damage to liver, kidney.The result of use of the more existing plaster that is used for the treatment of lumbago and skelalgia is also not ideal enough, and its main cause is: material choice inadequately accurately, the active constituent content permeability low, plaster in the plaster is not good.

Summary of the invention

The object of the present invention is to provide a kind of plaster that is used for the treatment of lumbago and skelalgia, accurate and effective component content height of these plaster materials and good penetrability.

For achieving the above object, adopt following scheme:

The present invention the plaster that is used for the treatment of lumbago and skelalgia that provides is provided is made by the following dosage proportion raw material: Oleum sesami 1550～1650 grams, Plumbum preparatium 980～1100 grams, Herba speranskiae tuberculatae 40～50 grams, Semen Strychni 28～38 grams, Ramulus Cinnamomi 25～35 grams, Fructus Capsici 60～70 grams, Fructus Piperis Longi 36～45 grams, Radix Gentianae Macrophyllae 38～48 grams, Radix Angelicae Pubescentis 50～60 grams, Rhizoma Zingiberis 85～95 grams, Scolopendra 27～37 grams, Borneolum Syntheticum 30～40 grams, Flos Daturae 29～40 grams, Caulis Sinomenii 35～45 grams, Rhizoma Curcumae 25～35 grams, Rhizoma Corydalis 40～50 grams, Zaocys 35～45 grams, 10～20 milliliters of azones, nano-ceramic powder 10～20 grams.

The preparation method of plaster that is used for lumbago and skelalgia provided by the invention is: Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, after treating that Plumbum preparatium and Oleum sesami are combined to paste, cream is poured in the cold water slowly, make cream in water, be cooled to band shape, after treating that cream condenses, taking-up was soaked in water 7 after pinching pressure, during, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate; Scolopendra, Borneolum Syntheticum were worn into the powder of 110 mesh sieves, and it is standby to obtain the spice powder; With Herba speranskiae tuberculatae, Semen Strychni, Ramulus Cinnamomi, Fructus Capsici, Fructus Piperis Longi, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Rhizoma Zingiberis, Flos Daturae, Caulis Sinomenii, Rhizoma Curcumae, Rhizoma Corydalis, Zaocys, be soaked in water 20～30 hours after, water decocts 2～3 times, each back extracting juice that decocts removes slag, then the medicine juice that obtains is merged the back and concentrate, obtain spice extractum; With ointment substrate heating and melting, add spice extractum, spice powder, nano-ceramic powder, azone then and fully mix, obtain ointment; The cream of getting it filled gram beach is being mounted on the backing material, treat that ointment is cooled to solid after, both plaster.

The present invention is a material medicine that to be selected pointedly have curative effect to lumbago and skelalgia in prescription, and the 2nd, selected azone, nano-ceramic powder for use.The effect of azone, nano-ceramic powder is respectively: azone is a kind of cutaneous permeable agent, and it is added in the pharmaceutical formulation, can improve the effect that drug transdermal absorbs; Nano-ceramic powder can absorb outside energy, promotes the absorption of human body to medicine.

In the preparation method of plaster that is used for the treatment of lumbago and skelalgia provided by the invention,, can guarantee content of effective in the plaster, and traditional way with spice " fried endure withered " can be destroyed the many effective ingredient in the spice with the spice water boiling and extraction.

As seen the plaster that is used for the treatment of lumbago and skelalgia provided by the invention has the advantages that medication is accurate, penetration is strong, active constituent content is high, when it uses, by absorbing outside energy and human body heat energy, has stronger penetrating power, can infiltrate skin and subcutaneous tissue, produce resonant absorption effects with hydrone in the human body cell, play microcirculation improvement and improve tissue metabolism's nutrition, promote the effect of the absorption of inflammation exudate, and reach relaxing muscles and tendons to promote blood circulation, cold expelling analgesic therapy, improve blood circulation, promote the effect that damaged tissue is repaired as early as possible.It has curative effect preferably to the treatment lumbago and skelalgia.

The specific embodiment

Further specify the present invention below in conjunction with embodiment.

Embodiment

In the present embodiment, the concrete consumption proportion that is used for the treatment of used each raw material of plaster of lumbago and skelalgia is: Oleum sesami 1600 grams, Plumbum preparatium 1000 grams, Herba speranskiae tuberculatae 45 grams, Semen Strychni 35 grams, Ramulus Cinnamomi 30 grams, Fructus Capsici 65 grams, Fructus Piperis Longi 40 grams, Radix Gentianae Macrophyllae 42 grams, Radix Angelicae Pubescentis 55 grams, Rhizoma Zingiberis 90 grams, Scolopendra 35 grams, Borneolum Syntheticum 35 grams, Flos Daturae 35 grams, Caulis Sinomenii 40 grams, Rhizoma Curcumae 30 grams, Rhizoma Corydalis 45 grams, Zaocys 40 grams, 15 milliliters of azones, nano-ceramic powder 15 grams.

The preparation method of the plaster that is used for the treatment of lumbago and skelalgia that present embodiment provides has following concrete steps:

1, Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, after treating that Plumbum preparatium and Oleum sesami are combined to paste, cream is poured in the cold water slowly, make cream in water, be cooled to band shape, after treating that cream condenses, taking-up was soaked in water 7 after pinching pressure, during, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate;

2, Scolopendra, Borneolum Syntheticum were worn into the powder of 110 mesh sieves, it is standby to obtain the spice powder;

3, Herba speranskiae tuberculatae, Semen Strychni, Ramulus Cinnamomi, Fructus Capsici, Fructus Piperis Longi, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Rhizoma Zingiberis, Flos Daturae, Caulis Sinomenii, Rhizoma Curcumae, Rhizoma Corydalis, Zaocys were soaked in water 20～30 hours after, water decocts 2～3 times, amount of water is good for being higher than spice 2～3cm, decoct to liquid medicine boiling back at every turn, decocted 40～50 minutes again, each back extracting juice that decocts removes slag, then the medicine juice that obtains is merged the back and concentrate,, obtain spice extractum to becoming to hang the flag shape with the sticking medicine juice that goes of Glass rod;

3, with ointment substrate heating and melting, be cooled to 65～75 ℃, add spice extractum, spice powder, nano-ceramic powder, azone then and fully mix, obtain ointment; Cream 9～10 gram beach of getting it filled are being mounted on the backing material, mount the backing material and adopt the medical no yarn adhesive plaster of desensitization, treat that ointment is cooled to solid after, both one force on;

5, the plaster that makes is packed into seal in the aluminium plastic bag.

Above-described azone, nano-ceramic powder are the commercially available prod, and azone is the standardized product that is used for pharmaceuticals industry.

In addition, this ointment should be contained in the container of sealing, places drying, the keeping of shady and cool place.

For better checking curative effect of the present invention, below contrast test by curative effect group, matched group, further specify the beneficial effect of plaster treatment dysmenorrhea provided by the invention:

1 grouping and Therapeutic Method

1.1 grouping successively is divided into treatment group and matched group with the patient at random by consultation time, 71 examples are organized in treatment, matched group 69 examples;

1.2 the treatment group uses plaster provided by the invention that the lumbago and skelalgia patient is treated;

1.3 matched group uses commercially available Moschus pain-stopping plaster that the lumbago and skelalgia patient is treated;

1.4 the course of treatment, treatment group and matched group were a course of treatment in equal 7 days;

1.5 using method, the treatment group is affixed on plaster provided by the invention after with little bakingization patient's pressure pain point, paste every day one, the application time of every subsides in summer is 2～4 hours, the application time of spring and autumn, every subsides in winter 4～6 hours pastes that the back is hot, the obvious person of burn feeling can throw off in advance, does not catch cold during the treatment, suitably warming, except that the interim medication of the heavier person of indivedual pain, generally without other therapies and medicine.

The related data of 2 treatment groups and matched group

2.1 distributing, sex sees Table one:

Table one

Group	The example number	The man	The woman
Group	The example number	The man	The woman	The treatment group	??71	??23	??48
Matched group	??69	??24	??45	The treatment group	??71	??23	??48

2.2 age distribution sees Table two

Table two

Group	The example number	Below 40 years old	41～60 years old	More than 60 years old
Group	The example number	Below 40 years old	41～60 years old	More than 60 years old	The treatment group	??71	??12	??46	??13
Matched group	??69	??8	??44	??17	The treatment group	??71	??12	??46	??13

2.3 course of disease situation sees Table three:

Table three

Group	The example number	Below 2 years	3～5 years	6～10 years	More than 10 years
Group	The example number	Below 2 years	3～5 years	6～10 years	More than 10 years	The treatment group	??71	??9	??42	??11	??9
Matched group	??60	??7	??40	??13	??9	The treatment group	??71	??9	??42	??11	??9

3 efficacy assessment standards

3.1 produce effects, waist or shank pain symptom disappear, and be local movable normal, recovers former work;

3.2 take a turn for the better, waist or shank pain symptom are alleviated, local movable no significant limitation, and it is influenced slightly to work;

3.3 invalid, after 2 each course of treatment of treatment, waist or shank pain symptom do not have obviously and alleviate.

4 result of the tests (after 2 courses of treatment) see Table four

Table four

Group	The example number	Produce effects	Take a turn for the better	Invalid	Total effective rate
Group	The example number	Produce effects	Take a turn for the better	Invalid	Total effective rate	The treatment group	??71	??31	??38	??2	??97.18％
Matched group	??69	??24	??40	??5	??92.75％	The treatment group	??71	??31	??38	??2	??97.18％

By above test as can be seen, plaster provided by the invention has significant curative effect to the treatment of lumbago and skelalgia.

Claims

1, the plaster that is used for the treatment of lumbago and skelalgia is characterized in that it is made by the following dosage proportion raw material: Oleum sesami 1550～1650 grams, Plumbum preparatium 980～1100 grams, Herba speranskiae tuberculatae 40～50 grams, Semen Strychni 28～38 grams, Ramulus Cinnamomi 25～35 grams, Fructus Capsici 60～70 grams, Fructus Piperis Longi 36～45 grams, Radix Gentianae Macrophyllae 38～48 grams, Radix Angelicae Pubescentis 50～60 grams, Rhizoma Zingiberis 85～95 grams, Scolopendra 27～37 grams, Borneolum Syntheticum 30～40 grams, Flos Daturae 29～40 grams, Caulis Sinomenii 35～45 grams, Rhizoma Curcumae 25～35 grams, Rhizoma Corydalis 40～50 grams, Zaocys 35～45 grams, 10～20 milliliters of azones, nano-ceramic powder 10～20 grams.

2, the plaster that is used for the treatment of lumbago and skelalgia according to claim 1 is characterized in that the consumption proportion of each raw material is: Oleum sesami 1600 grams, Plumbum preparatium 1000 grams, Herba speranskiae tuberculatae 45 grams, Semen Strychni 35 grams, Ramulus Cinnamomi 30 grams, Fructus Capsici 65 grams, Fructus Piperis Longi 40 grams, Radix Gentianae Macrophyllae 42 grams, Radix Angelicae Pubescentis 55 grams, Rhizoma Zingiberis 90 grams, Scolopendra 35 grams, Borneolum Syntheticum 35 grams, Flos Daturae 35 grams, Caulis Sinomenii 40 grams, Rhizoma Curcumae 30 grams, Rhizoma Corydalis 45 grams, Zaocys 40 grams, 15 milliliters of azones, nano-ceramic powder 15 grams.

3, the described preparation method that is used for the treatment of the plaster of lumbago and skelalgia of a kind of claim 1, it is characterized in that may further comprise the steps: Oleum sesami is tempered, when oily temperature reaches 320～330 ℃, Plumbum preparatium is added, treat that Plumbum preparatium and Oleum sesami are combined to paste after, slowly pour into cream in the cold water, make cream in water, be cooled to band shape, treat that cream condenses after, take out and to be soaked in water 7 after pinching pressure, during this time, change water every day once, change water at every turn and all cream is pinched pressure, obtain ointment substrate; Scolopendra, Borneolum Syntheticum were worn into the powder of 110 mesh sieves, and it is standby to obtain the spice powder; After Herba speranskiae tuberculatae, Semen Strychni, Ramulus Cinnamomi, Fructus Capsici, Fructus Piperis Longi, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Rhizoma Zingiberis, Flos Daturae, Caulis Sinomenii, Rhizoma Curcumae, Rhizoma Corydalis, Zaocys be soaked in water 20～30 hours, water decocts 2～3 times, each back extracting juice that decocts removes slag, then the medicine juice that obtains is merged the back and concentrate, obtain spice extractum; With ointment substrate heating and melting, add spice extractum, borneol powder, nano-ceramic powder, azone then and fully mix, obtain ointment; The cream of getting it filled gram beach is being mounted on the backing material, treat that ointment is cooled to solid after, both plaster.