CN104958584A - Plaster for treatment of infant diarrhea - Google Patents

Abstract

The invention discloses a plaster for treatment of infant diarrhea and relates to plasters. The plaster is prepared by 1250-1350 g of hot melt adhesive, 20-30 g of husked kaoliang, 20-30 g of granatum, 50-60 g of hawthorn, 40-60 g of green tangerine peel, 30-40 g of ginseng, 45-55 g of the root of fangfeng, 30-40 g of liquorice, 35-45 g of the root of balloonflower, 15-25 g of the root of kudzu vine, 15-25 g of rice sprout, 45-55 g of the rhizome of Chinese goldthread, 45-55 g of bighead atractylodes rhizome, 55-65 g of fried medicated leaven, 70-80 g of wrinkled giant hyssop , 60-80 g of bark of magnolia and 10-20 ml of peppermint oil. The plaster for treatment of infant diarrhea has the advantages of high accuracy, high permeability and high content of active ingredient. During use, external energy and heat of human bodies are absorbed, and the plaster has high permeability and can permeate skin and hypodermis to achieve effects of dispersing stagnation and dredging the collaterals, reinforcing nephridium and removing stasis, and removing ascites by enhancing metabolism, and accordingly has good curative effect in treatment of infant diarrhea.

Description

Be used for the treatment of the plaster of infantile diarrhea

Technical field

The present invention relates to a kind of plaster, be specifically related to a kind of plaster being used for the treatment of infantile diarrhea.

Background technology

Diarrhoea is a kind of common sympton, is commonly called as " diarrhoea ", and refer to that defecation frequency is significantly more than the frequency be on ordinary days accustomed to, excrement matter is thin, and moisture increases, and every day, feces volume was more than 200g, or containing non-digest food or pus and blood, mucus.Diarrhoea is normal with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea point acute and chronic two classes.Sharply, the course of disease is within 2 ~ 3 weeks in acute diarrhea morbidity.Chronic diarrhea refer to the course of disease more than two months or the intermission in 2 ~ 4 weeks recurrent diarrhoea.

At present, clinically to infantile diarrhea usually adopt oral, transfusion treat, oral medicine stimulates larger to gastrointestinal, patient is difficult to stand, transfusion then can have operation in various degree to liver, kidney, specifically for infant soon of being born, takes in reaction larger to medicine, use mouth to enter medicine, potential danger may be there is.

Summary of the invention

Technical problem to be solved by this invention be to provide a kind of materials accurately, at the high and plaster being used for the treatment of infantile diarrhea of good penetrability of effective component content.

Technical problem to be solved by this invention realizes by the following technical solutions:

Be used for the treatment of a plaster for infantile diarrhea, be made up of following crude drug:

PUR 1250-1350g, sorghum rice 20-30g, Pericarpium Granati 20-30g, Fructus Crataegi 50-60g, Pericarpium Citri Reticulatae Viride 40-60g, Radix Ginseng 30-40g, Radix Saposhnikoviae 45-55g, Radix Glycyrrhizae 30-40g, Radix Platycodonis 35-45g, Radix Puerariae 15-25g, Fructus Setariae Germinatus 15-25g, Rhizoma Coptidis 45-55g, Rhizoma Atractylodis Macrocephalae 45-55g, Massa Medicata Fermentata preparata 55-65g, Herba Pogostemonis 70-80g, Cortex Magnoliae Officinalis 60-80g, Oleum menthae 10-20mL.

The preferred amounts of each raw material is: PUR 1300g, sorghum rice 25g, Pericarpium Granati 25g, Fructus Crataegi 55g, Pericarpium Citri Reticulatae Viride 45g, Radix Ginseng 35g, Radix Saposhnikoviae 50g, Radix Glycyrrhizae 35g, Radix Platycodonis 40g, Radix Puerariae 20g, Fructus Setariae Germinatus 20g, Rhizoma Coptidis 50g, Rhizoma Atractylodis Macrocephalae 50g, Massa Medicata Fermentata preparata 60g, Herba Pogostemonis 75g, Cortex Magnoliae Officinalis 70g, Oleum menthae 15mL.

Another object of the present invention is to provide a kind of method preparing plaster of the present invention:

The PUR heating being used for making plaster is reached 80-100 DEG C, is then cooled to 60 DEG C, obtains ointment base; After being soaked in water 2-3 days by other crude drug, then use soak by water 2-3 time, after each decoction, extracting juice removes slag, and concentrates, obtain spice extractum after then being merged by the medicine juice obtained; By ointment base heating and melting, then add spice extractum, Oleum menthae is fully uniformly mixed, obtain ointment; Get it filled cream beach in framed back material, is cooled to after solid until ointment, obtains plaster.

The present invention one has been selected pointedly to the medicable material medicine of infantile diarrhea tool in formula, and two is selected Oleum menthae, and Oleum menthae is a kind of cutaneous permeable agent, and it is added in pharmaceutical formulation, can improve the effect of Drug Percutaneous Absorption.

Provided by the inventionly be used for the treatment of in the preparation method of plaster of front infantile diarrhea, by spice water boiling and extraction, the content of effective ingredient in plaster can be ensured, and traditional by the way of spice " fried endure withered ", the many effective ingredient in spice can be destroyed.

The invention has the beneficial effects as follows: the plaster being used for the treatment of infantile diarrhea provided by the invention has the advantages that medication is accurate, penetration is strong, active constituent content is high, when it uses, by absorbing outside energy and human body heat energy, there is stronger penetrating power, skin and subcutaneous tissue can be infiltrated, reach the effect of disperse blood stasis and dredge collateral, the kidney invigorating eliminating stagnation, promote the circulation of qi and water, it has good curative effect to treatment infantile diarrhea.

Detailed description of the invention

The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.

Embodiment 1

Heat-obtaining melten gel 1250g, sorghum rice 20g, Pericarpium Granati 20g, Fructus Crataegi 50g, Pericarpium Citri Reticulatae Viride 40g, Radix Ginseng 30g, Radix Saposhnikoviae 45g, Radix Glycyrrhizae 30g, Radix Platycodonis 35g, Radix Puerariae 15g, Fructus Setariae Germinatus 15g, Rhizoma Coptidis 45g, Rhizoma Atractylodis Macrocephalae 45g, Massa Medicata Fermentata preparata 55g, Herba Pogostemonis 70g, Cortex Magnoliae Officinalis 60g, Oleum menthae 10mL.

Preparation method is as follows:

The PUR heating being used for making plaster is reached 90 DEG C, is then cooled to 60 DEG C, obtains ointment base; Sorghum rice, Pericarpium Granati, Fructus Crataegi, Pericarpium Citri Reticulatae Viride, Radix Ginseng, Radix Saposhnikoviae, Radix Glycyrrhizae, Radix Platycodonis, Radix Puerariae, Fructus Setariae Germinatus, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Herba Pogostemonis, Cortex Magnoliae Officinalis are soaked in water 3 days, with soak by water 3 times, amount of water is gross weight 2 times, each decoction is after liquid medicine boiling, decoct 25 minutes again, after each decoction, extracting juice removes slag, concentrated after then being merged by the medicine juice obtained, and obtains spice extractum; By ointment base heating and melting, then add spice extractum, Oleum menthae is fully uniformly mixed, obtain ointment; Get it filled cream 9 grams of beach in framed back material, and framed back material adopts desensitization medical non-woven adhesive plaster, is cooled to after solid, obtains one and force on until ointment; Drying is placed in, the keeping of shady and cool place by sealing and leave in the container of sealing in multiple for obtained plaster dress aluminium plastic bag.

The present invention is used for the treatment of the using method of the plaster of infantile diarrhea: by plaster with after little baking, be affixed on umbilicus place, stick 18-24 hour, the next day 1 time, be for 5 times a course for the treatment of, continuously 3 courses for the treatment of of treatment.

Embodiment 2

Heat-obtaining melten gel 1300g, sorghum rice 25g, Pericarpium Granati 25g, Fructus Crataegi 55g, Pericarpium Citri Reticulatae Viride 45g, Radix Ginseng 35g, Radix Saposhnikoviae 50g, Radix Glycyrrhizae 35g, Radix Platycodonis 40g, Radix Puerariae 20g, Fructus Setariae Germinatus 20g, Rhizoma Coptidis 50g, Rhizoma Atractylodis Macrocephalae 50g, Massa Medicata Fermentata preparata 60g, Herba Pogostemonis 75g, Cortex Magnoliae Officinalis 70g, Oleum menthae 15mL.

Preparation method is as follows:

The PUR heating being used for making plaster is reached 90 DEG C, is then cooled to 60 DEG C, obtains ointment base; Sorghum rice, Pericarpium Granati, Fructus Crataegi, Pericarpium Citri Reticulatae Viride, Radix Ginseng, Radix Saposhnikoviae, Radix Glycyrrhizae, Radix Platycodonis, Radix Puerariae, Fructus Setariae Germinatus, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Herba Pogostemonis, Cortex Magnoliae Officinalis are soaked in water 2 days, with soak by water 2 times, amount of water is gross weight 2 times, each decoction is after liquid medicine boiling, decoct 20 minutes again, after each decoction, extracting juice removes slag, concentrated after then being merged by the medicine juice obtained, and obtains spice extractum; By ointment base heating and melting, then add spice extractum, Oleum menthae is fully uniformly mixed, obtain ointment; Get it filled cream 8 grams of beach in framed back material, and framed back material adopts desensitization medical non-woven adhesive plaster, is cooled to after solid, obtains one and force on until ointment; Drying is placed in, the keeping of shady and cool place by sealing and leave in the container of sealing in multiple for obtained plaster dress aluminium plastic bag.

The present invention is used for the treatment of the using method of the plaster of infantile diarrhea: by plaster with after little baking, be affixed on umbilicus place, stick 18-24 hour, the next day 1 time, be for 5 times a course for the treatment of, continuously 3 courses for the treatment of of treatment.

In order to better verify curative effect of the present invention, below by way of the contrast experiment of curative effect group, matched group, further illustrate the beneficial effect of plaster provided by the invention to infantile diarrhea.

1, grouping and Therapeutic Method

1.1, divide into groups, successively patient is divided into treatment group and matched group at random by consultation time, treatment group 15 example, matched group 15 example;

1.2, treatment group, uses plaster provided by the invention to treat infantile diarrhea patient;

1.3, matched group, uses commercially available youngster to rush down to stop granule and treats infantile diarrhea patient;

1.4, the course for the treatment of, treatment group and matched group are a course for the treatment of in equal 15 days.

2, the related data for the treatment of group and matched group.

2.1, age distribution is in table one

Table one

2.2, course of disease situation is in table two

Table two

Group	Number of cases	Less than 2 days	3-5 days	6-10 days	More than 10 days
						Treatment group	15	3	3	4	5
Matched group	15	3	3	4	5

2.3, disease class typing, in table three

Table three

Group	Number of cases	Slightly	Moderate	Severe
					Treatment group	15	3	5	7
Matched group	15	3	5	6

3, efficacy assessment standard

3.1, cure: defecation is unobstructed, normally;

3.2, take a turn for the better: stool is shaped, slightly loose stool;

3.3, invalid, symptom and every inspection are all without improvement.

4, experimental result (after 3 courses for the treatment of) is in table four

Table four

Group	Number of cases	Cure	Take a turn for the better	Invalid	Total effective rate %
						Treatment group	15	13	1	1	93.3％
Matched group	15	8	2	5	66.7％

As can be seen from above experiment, plaster provided by the invention has more significant curative effect for treatment infantile diarrhea.

More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (3)

1. be used for the treatment of the plaster of infantile diarrhea, be made up of following crude drug:

PUR 1250-1350g, sorghum rice 20-30g, Pericarpium Granati 20-30g, Fructus Crataegi 50-60g, Pericarpium Citri Reticulatae Viride 40-60g, Radix Ginseng 30-40g, Radix Saposhnikoviae 45-55g, Radix Glycyrrhizae 30-40g, Radix Platycodonis 35-45g, Radix Puerariae 15-25g, Fructus Setariae Germinatus 15-25g, Rhizoma Coptidis 45-55g, Rhizoma Atractylodis Macrocephalae 45-55g, Massa Medicata Fermentata preparata 55-65g, Herba Pogostemonis 70-80g, Cortex Magnoliae Officinalis 60-80g, Oleum menthae 10-20mL.

2. the plaster being used for the treatment of infantile diarrhea according to claim 1, is characterized in that: the preferred amounts of each raw material is: PUR 1300g, sorghum rice 25g, Pericarpium Granati 25g, Fructus Crataegi 55g, Pericarpium Citri Reticulatae Viride 45g, Radix Ginseng 35g, Radix Saposhnikoviae 50g, Radix Glycyrrhizae 35g, Radix Platycodonis 40g, Radix Puerariae 20g, Fructus Setariae Germinatus 20g, Rhizoma Coptidis 50g, Rhizoma Atractylodis Macrocephalae 50g, Massa Medicata Fermentata preparata 60g, Herba Pogostemonis 75g, Cortex Magnoliae Officinalis 70g, Oleum menthae 15mL.

3. prepare the plaster method that be used for the treatment of infantile diarrhea of claim 1-2 described in any one, it is characterized in that:

The PUR heating being used for making plaster is reached 80-100 DEG C, is then cooled to 60 DEG C, obtains ointment base; After being soaked in water 2-3 days by other crude drug, then use soak by water 2-3 time, after each decoction, extracting juice removes slag, and concentrates, obtain spice extractum after then being merged by the medicine juice obtained; By ointment base heating and melting, then add spice extractum, Oleum menthae is fully uniformly mixed, obtain ointment; Get it filled cream beach in framed back material, is cooled to after solid until ointment, obtains plaster.