CN103100010A - Drug for treatment of rheumatic arthritis - Google Patents
Drug for treatment of rheumatic arthritis Download PDFInfo
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- CN103100010A CN103100010A CN2013100534254A CN201310053425A CN103100010A CN 103100010 A CN103100010 A CN 103100010A CN 2013100534254 A CN2013100534254 A CN 2013100534254A CN 201310053425 A CN201310053425 A CN 201310053425A CN 103100010 A CN103100010 A CN 103100010A
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Abstract
The invention discloses a drug for treatment of rheumatic arthritis. The drug is characterized in that it is a granule, a tablet or a capsule made from the following raw material drugs by weight: 2-4 of masson pine bark, 1.5-2.5 of field thistle, 2.3-3.5 of white paeony roots, 2-4 of roots of sageretia theezans, 1.5-2.5 of honeysuckle, 2-4 of panax notoginseng, 1.5-2.5 of sodium bicarbonate, 2-4 of Rhizoma Heterosmilacis Japonicae, 1.5-2.5 of radix rehmanniae, and 1.5-2.5 of eleusine indica. The drug provided in the invention is used for treating rheumatic arthritis, and after taking it, a good curative effect can be achieved. The drug has the efficacy of joint swelling reducing, pain relieving, and joint function recovery and improvement, etc. Through preliminary clinical verification, the drug has a rheumatic arthritis cure rate up to 96.5% and an effective rate of 100%. In addition, the drug also has the characteristics of easily available medicinal raw materials, and convenient administration, etc.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation that is used for the treatment of rheumatic arthritis.
Background technology
Rheumatic arthritis is a kind of commonly encountered diseases and frequently-occurring disease.At present, doctor trained in Western medicine uses the medicines such as glucocorticoids, immunosuppressant that this disease is treated more, though certain curative effect is arranged, therapeutic effect is unsatisfactory, and such medicine also has suitable toxic and side effects, and life-time service is larger to patient's harm.Through a large amount of clinical verifications, though Chinese medicine decoction has certain therapeutic effect for treatment rheumatic arthritis, but decoction decocting is cumbersome, and the patient is difficult to adhere to for a long time taking.In addition, also there are clinically a large amount of Chinese medicine preparation to be applied to treat rheumatic arthritis, therapeutic effect is different, this class Chinese medicine preparation has various dosage forms, but medicament or the raw material of Chinese medicine of employing compatibility are nearly more than tens kinds mostly, the manufacturing process very complex is so just applied to it and has been brought many restrictions.
Summary of the invention
Task of the present invention is to provide a kind of medicine for the treatment of rheumatic arthritis, and this medicine realizes that determined curative effect, medicine material are simple and easy to, and taking convenience.
Its technical solution is:
A kind of medicine for the treatment of rheumatic arthritis, granule, tablet or the capsule made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 2～4, Herba Cirsii 1.5～2.5, the Radix Paeoniae Alba 2.3～3.5, Sageretia theezans root 2～4, Flos Lonicerae 1.5～2.5, Radix Notoginseng 2～4, sodium bicarbonate 1.5～2.5, hargil Poria 2～4, Radix Rehmanniae 1.5～2.5, Herba Eleusines Indicae 1.5～2.5.
As a kind of preferred technical scheme, a kind of medicine for the treatment of rheumatic arthritis, granule, tablet or the capsule made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 3, Herba Cirsii 2, the Radix Paeoniae Alba 2.5, Sageretia theezans root 3, Flos Lonicerae 2, Radix Notoginseng 3, sodium bicarbonate 2, hargil Poria 3, Radix Rehmanniae 2, Herba Eleusines Indicae 2.
The present invention can be made into granule, capsule or tablet, and Coming-of-Age Day takes three times, each serving with 5～10 grams.
Pharmacology analysis: the horse hair Cortex Pini Massonianae in the present invention, namely the dried bark of Pinus massoniana Lamb, have wind-damp dispelling, blood circulation promoting and blood stasis dispelling, pain relieving, hemostasis, the loose effect that swells and ache; Herba Cirsii, another name claims field thistle, luxuriant dish etc., has the effect of cooling blood for hemostasis, removing blood stasis to reduce swelling; The Radix Paeoniae Alba has except effects such as arthralgia due to stagnation of blood, broken heavily fortified point amass, pain relieving, QI invigorating; The Sageretia theezans root has the effects such as wind-damp dispelling, benefit muscles and bones; Flos Lonicerae has the effects such as dispelling wind-heat, removing summer-heat blood poison; Radix Notoginseng has the effects such as dissipating blood stasis hemostasis, subduing swelling and relieving pain; Sodium bicarbonate is weak base, can be rapidly after for oral administration in and gastric acid, a little less than its antiacid effect and of short duration; The hargil Poria has the effects such as detoxifcation dehumidifying, easing joint movement; Radix Rehmanniae has clearing away heat and cooling blood, the effects such as YIN nourishing and the production of body fluid promoting; Herba Eleusines Indicae has the effects such as heat clearing away, dampness removing.Above-mentioned Ten Herbs and use can have the detoxifcation dehumidifying, strong muscles and bones, and reducing swelling and alleviating pain, easing joint movement, the effects such as expelling wind and removing dampness have curative effect preferably for treatment rheumatic arthritis.
The present invention is used for the treatment of rheumatic arthritis, takes the rear curative effect preferably that all has, and has that arthroncus is disappeared, pain relief, and joint functional recovery improvement texts.Through the clinical principium checking, can reach 96.5% for the rheumatic arthritis cure rate, effective percentage is 100%.In addition, also have medicine material and be simple and easy to, and the characteristics such as taking convenience.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of medicine for the treatment of rheumatic arthritis, the granule of being made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 2, Herba Cirsii 1.5, the Radix Paeoniae Alba 2.3, Sageretia theezans root 2, Flos Lonicerae 1.5, Radix Notoginseng 2, sodium bicarbonate 1.5, hargil Poria 2, Radix Rehmanniae 1.5, Herba Eleusines Indicae 1.5.
Said medicine can adopt following preparation method, and the method comprising the steps of:
A is with horse hair Cortex Pini Massonianae 200 grams, Herba Cirsii 150 grams, the Radix Paeoniae Alba 230 grams, Sageretia theezans root 200 grams, Radix Notoginseng 200 grams, hargil Poria 200 grams and Herba Eleusines Indicae 150 grams, mix, then decoct with water twice, add the water of 10～12 times at every turn, the each decoction 3 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, then heating is concentrated into every ml and is equivalent to crude drug 2 grams.Add ethanol, the ethanol content that adds reaches more than 75% again, after static 12 hours, filters, and reclaims ethanol, obtains solids, and this solids vacuum drying is ground into the extractum fine powder, and is standby.
B is with Flos Lonicerae 150 grams, sodium bicarbonate 150 grams and Radix Rehmanniae 150 grams, mix, then decoct with water twice, add the water of 8～10 times at every turn, the each decoction 2 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, the clear paste of the relative density 1.30～1.50 when then heating is concentrated into 50 ℃.
The clear paste that the extractum fine powder that c obtains step a, step b obtain and maltodextrin are made granulated quickly dissolving according to conventional method, every bag of granule pastille 10 grams in the ratio mix homogeneously of 4:3:2.
Usage: above-mentioned one bag of granule is poured in cup, added 100ml hot water to rush molten, drink-service gets final product; Every day 3 times.
Through the clinical principium checking, the medicine that this example obtains can reach 95.5% for the rheumatic arthritis cure rate.
Embodiment 2
A kind of medicine for the treatment of rheumatic arthritis, the granule of being made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 4, Herba Cirsii 2.5, the Radix Paeoniae Alba 3.5, Sageretia theezans root 4, Flos Lonicerae 2.5, Radix Notoginseng 4, sodium bicarbonate 2.5, hargil Poria 4, Radix Rehmanniae 2.5, Herba Eleusines Indicae 2.5.
Said medicine can adopt following preparation method, and the method comprising the steps of:
A is with horse hair Cortex Pini Massonianae 400 grams, Herba Cirsii 250 grams, the Radix Paeoniae Alba 350 grams, Sageretia theezans root 400 grams, Radix Notoginseng 400 grams, hargil Poria 400 grams and Herba Eleusines Indicae 250 grams, mix, then decoct with water twice, add the water of 10～12 times at every turn, the each decoction 3 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, then heating is concentrated into every ml and is equivalent to crude drug 2 grams.Add ethanol, the ethanol content that adds reaches more than 75% again, after static 12 hours, filters, and reclaims ethanol, obtains solids, and this solids vacuum drying is ground into the extractum fine powder, and is standby.
B is with Flos Lonicerae 250 grams, sodium bicarbonate 250 grams and Radix Rehmanniae 250 grams, mix, then decoct with water twice, add the water of 8～10 times at every turn, the each decoction 2 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, the clear paste of the relative density 1.30～1.50 when then heating is concentrated into 50 ℃.
The clear paste that the extractum fine powder that c obtains step a, step b obtain and maltodextrin are made granulated quickly dissolving according to conventional method, every bag of granule pastille 10 grams in the ratio mix homogeneously of 4:3:2.
Usage: above-mentioned one bag of granule is poured in cup, added 100ml hot water to rush molten, drink-service gets final product; Every day 3 times.
Through the clinical principium checking, the medicine that this example obtains can reach 96% for the rheumatic arthritis cure rate.
Embodiment 3
A kind of medicine for the treatment of rheumatic arthritis, the granule of being made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 3, Herba Cirsii 2, the Radix Paeoniae Alba 2.5, Sageretia theezans root 3, Flos Lonicerae 2, Radix Notoginseng 3, sodium bicarbonate 2, hargil Poria 3, Radix Rehmanniae 2, Herba Eleusines Indicae 2.
Said medicine can adopt following preparation method, and the method comprising the steps of:
A is with horse hair Cortex Pini Massonianae 300 grams, Herba Cirsii 200 grams, the Radix Paeoniae Alba 250 grams, Sageretia theezans root 300 grams, Radix Notoginseng 300 grams, hargil Poria 300 grams and Herba Eleusines Indicae 200 grams, mix, then decoct with water twice, add the water of 10～12 times at every turn, the each decoction 3 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, then heating is concentrated into every ml and is equivalent to crude drug 2 grams.Add ethanol, the ethanol content that adds reaches more than 75% again, after static 12 hours, filters, and reclaims ethanol, obtains solids, and this solids vacuum drying is ground into the extractum fine powder, and is standby.
B is with Flos Lonicerae 200 grams, sodium bicarbonate 200 grams and Radix Rehmanniae 200 grams, mix, then decoct with water twice, add the water of 8～10 times at every turn, the each decoction 2 hours, decocting liquid filters, and twice filtrate is merged, and mix homogeneously, the clear paste of the relative density 1.30～1.50 when then heating is concentrated into 50 ℃.
The clear paste that the extractum fine powder that c obtains step a, step b obtain and maltodextrin are made granulated quickly dissolving according to conventional method, every bag of granule pastille 10 grams in the ratio mix homogeneously of 4:3:2.
Usage: above-mentioned one bag of granule is poured in cup, added 100ml hot water to rush molten, drink-service gets final product; Every day 3 times.
Through the clinical principium checking, the medicine that this example obtains can reach 96.5% for the rheumatic arthritis cure rate.
In addition to the implementation, medicine of the present invention can also be made tablet or capsule.
The relevant technologies content of not addressing in aforesaid way is taked or is used for reference prior art and can realize.
Need to prove, those skilled in the art can also make such or such easy variation pattern under the instruction of this description, such as equivalent way, or obvious mode of texturing.Above-mentioned variation pattern all should be within protection scope of the present invention.
Claims (2)
1. medicine for the treatment of rheumatic arthritis is characterized in that granule, tablet or the capsule made by the crude drug of following weight portion:
Horse hair Cortex Pini Massonianae 2～4, Herba Cirsii 1.5～2.5, the Radix Paeoniae Alba 2.3～3.5, Sageretia theezans root 2～4, Flos Lonicerae 1.5～2.5, Radix Notoginseng 2～4, sodium bicarbonate 1.5～2.5, hargil Poria 2～4, Radix Rehmanniae 1.5～2.5, Herba Eleusines Indicae 1.5～2.5.
2. a kind of medicine for the treatment of rheumatic arthritis according to claim 1 is characterized in that the weight portion proportioning of above-mentioned raw materials medicine is:
Horse hair Cortex Pini Massonianae 3, Herba Cirsii 2, the Radix Paeoniae Alba 2.5, Sageretia theezans root 3, Flos Lonicerae 2, Radix Notoginseng 3, sodium bicarbonate 2, hargil Poria 3, Radix Rehmanniae 2, Herba Eleusines Indicae 2.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100534254A CN103100010A (en) | 2013-02-19 | 2013-02-19 | Drug for treatment of rheumatic arthritis |
| CN201310647066.5A CN103610982B (en) | 2013-02-19 | 2013-12-04 | A kind of medicine for the treatment of rheumatic arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100534254A CN103100010A (en) | 2013-02-19 | 2013-02-19 | Drug for treatment of rheumatic arthritis |
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| Publication Number | Publication Date |
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| CN103100010A true CN103100010A (en) | 2013-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013100534254A Pending CN103100010A (en) | 2013-02-19 | 2013-02-19 | Drug for treatment of rheumatic arthritis |
| CN201310647066.5A Expired - Fee Related CN103610982B (en) | 2013-02-19 | 2013-12-04 | A kind of medicine for the treatment of rheumatic arthritis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201310647066.5A Expired - Fee Related CN103610982B (en) | 2013-02-19 | 2013-12-04 | A kind of medicine for the treatment of rheumatic arthritis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103393824A (en) * | 2013-07-19 | 2013-11-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine containing radix aconiti preparata and preparation method thereof |
| CN103623091A (en) * | 2013-12-04 | 2014-03-12 | 武瑞美 | Medicament for external use for treating gout |
| CN104258316A (en) * | 2014-10-31 | 2015-01-07 | 蔡明杰 | Pharmaceutical composition for treating rheumatic arthritis and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579434A (en) * | 2008-05-15 | 2009-11-18 | 刘人源 | Traditional Chinese medicine preparation for curing femoral head necrosis and vasculitis |
| CN101919988A (en) * | 2009-06-10 | 2010-12-22 | 胡国伟 | Medicine compound for curing rheumatism rheumatoid arthritis and preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100368001C (en) * | 2005-05-27 | 2008-02-13 | 王楚清 | Medicine composition for treating rheumatic arthritis and rheumatoid arthritis, and its prepn. method |
| CN102526451A (en) * | 2010-12-15 | 2012-07-04 | 黄启仁 | Traditional Chinese medicine formula for activating tibia |
| CN102488879B (en) * | 2011-12-22 | 2014-02-05 | 赵国辉 | Medicinal composition for treating rheumatism |
-
2013
- 2013-02-19 CN CN2013100534254A patent/CN103100010A/en active Pending
- 2013-12-04 CN CN201310647066.5A patent/CN103610982B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579434A (en) * | 2008-05-15 | 2009-11-18 | 刘人源 | Traditional Chinese medicine preparation for curing femoral head necrosis and vasculitis |
| CN101919988A (en) * | 2009-06-10 | 2010-12-22 | 胡国伟 | Medicine compound for curing rheumatism rheumatoid arthritis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘健: "类风湿性关节炎中医药治疗进展", 《安徽中医学院学报》, vol. 17, no. 1, 31 January 1998 (1998-01-31), pages 60 - 64 * |
| 闫翠环等: "清热解毒法治疗类风湿关节炎研究进展", 《河北中医》, vol. 28, no. 9, 30 September 2006 (2006-09-30), pages 715 - 717 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103393824A (en) * | 2013-07-19 | 2013-11-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine containing radix aconiti preparata and preparation method thereof |
| CN103623091A (en) * | 2013-12-04 | 2014-03-12 | 武瑞美 | Medicament for external use for treating gout |
| CN103623091B (en) * | 2013-12-04 | 2015-04-15 | 武瑞美 | Medicament for external use for treating gout |
| CN104258316A (en) * | 2014-10-31 | 2015-01-07 | 蔡明杰 | Pharmaceutical composition for treating rheumatic arthritis and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103610982A (en) | 2014-03-05 |
| CN103610982B (en) | 2015-07-29 |
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Application publication date: 20130515 |