CN103156972B - Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury - Google Patents

Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury Download PDF

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CN103156972B
CN103156972B CN201310090977.2A CN201310090977A CN103156972B CN 103156972 B CN103156972 B CN 103156972B CN 201310090977 A CN201310090977 A CN 201310090977A CN 103156972 B CN103156972 B CN 103156972B
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fracture
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radix
rhizoma
traumatic injury
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刘玉伦
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Abstract

The invention relates to a traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury. The combination is prepared from internal and external medicines. The bulk pharmaceutical chemicals of the internal medicines comprise nux vomica, Chinese angelica, szechuan lovage rhizome, notoginseng, common club moss herb, rhizoma drynariae, himalayan teasel root, salvia miltiorrhiza, rhizoma corydalis and madder. The bulk pharmaceutical chemicals of the external medicines comprises dragon's blood, realgar, red flower, catecholamine, cinnabar, frankincense, myrrh, Chinese angelica root, paris polyphylla, borneol and musk. The external medicines of the invention have an effect of reducing swelling, and the internal medicines thereof have the effects of tonifying kidney and dredging collaterals, promoting reunion of fractured tendons and bones, and strengthening the therapeutic effect. The traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury provided by the invention has the advantages of reasonable combination, fast quick effect taking, high cure rate and no toxic side effect, and is suitable for the treatment of various fracture, hairline fracture and traumatic injury. Soft tissue injury, flesh bruises caused by traumatic injury and back bruises can be cured by internal or external taking, while the fracture, comminuted fracture or broken bone dislocation can be effectively treated by internal and external taking. Therefore, good therapeutic effect is provided for comminuted fracture or broken bone dislocation not being cured for a long time after surgeries in the hospital.

Description

A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury, belong to technical field of Chinese medicines.
Background technology
Fracture is commonly encountered diseases, it is clinical that to take fracture, pain, hemorrhage limitation of activity be feature, Most patients is at routine operation, very fast rehabilitation under symptomatic treatment, its pain of minority bone splits patient, swelling, fracture adopt conventional therapy, can not effectively control have an intense pain, obstinate swelling and union of fracture slow.Western medical treatment fracture normally operate on operation train wheel bridge or steel plate with steel nail fix, Gypsum Fibrosum is fixed, have an injection and hang water, rest quiet at home to recover oneself etc., such Therapeutic Method is slow, the fastest also take 3-5 month basic rehabilitation of ability, and senile fracture, bone fracture dislocation and comminuted fracture, the time of bone healing is just long, and recovery time is relevant with patient's body constitution.In addition, at knochenbruch, before healing firmly, to not be cautious use of Western medicine, especially avoid with the medicine containing hormone.By contrast, adopt TCM Therapy treatment fracture, bone injury to have more advantage.That the method for the treatment of by Chinese herbs bone injury has is for oral administration, external application, washout etc., and the showy reiolaena root-bark of the traditional Chinese medical science is varied, but its medication object is consistent, if drug matching is reasonable, just can reach the effect of fast fracture-setting, reducing swelling and alleviating pain; Common fracture can substantially heal about one month, and the fracture of joint bone, comminuted fracture and old man's fractures need many some times of prolongation, probably need within 40-60 days, can substantially heal.Application oral medicine and application compress treatment fracture are features of traditional Chinese medical science bonesetting.Middle medical drugs is determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, is generally two phases to fracture repair and Therapeutic Principle and minute sooner or later according to motherland's medical science.With blood stasis removing detumescence, pain relieving is main, take late period and strengthens muscle synthetism as main in early days.
Disclosed a kind of medicine for the treatment of fracture of CN101716266B and preparation method thereof, comprise bone-set plaster, bone knitting powder and bone-knitting capsule, bone-set plaster is comprised of Olibanum, Myrrha, Radix Clematidis, Radix Salviae Miltiorrhizae and Oleum sesami, Plumbum preparatium etc., bone knitting powder is called on etc. and to be formed by the Radix Astragali, Radix Angelicae Sinensis, Radix Glycyrrhizae, blood, and bone-knitting capsule is comprised of Radix Bupleuri, Radix Paeoniae Rubra, Radix Dipsaci, Semen Persicae etc.This scheme must adopt bone-set plaster and bone knitting powder or bone-knitting capsule to be used in conjunction with in use, and the preparation method of its bone-set plaster is complicated, and healing speed is not ideal enough.
Disclosed a kind of Chinese medicine composition for the treatment of fracture of CN102000165B and preparation method thereof, endo-medicine is: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Radix Notoginseng, Radix Achyranthis Bidentatae, Flos Carthami, Eupolyphaga Seu Steleophaga, Caulis Spatholobi, Rhizoma Drynariae, Rhizoma Polygoni Cuspidati, Fructus Psoraleae, Ramulus Sambuci Williamsii, Herba Lycopodii, Caulis Seu Folium Lespedezae Bicoloris, Pheretima, Radix Paeoniae Rubra; External used medicine is: Myrrha, Olibanum, Radix Dipsaci, Radix Notoginseng, Flos Carthami, Sanguis Draxonis, Semen Strychni, Zaocys, Radix Aconiti Preparata, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Herba speranskiae tuberculatae.The method for making of this scheme external used medicine is complicated, and treatment time is longer.
Micropowder medicament of the disclosed a kind of set a broken bone of CN101961446B and preparation method thereof, formula comprises Pyritum, Herba Rhodiolae Henryi, Olibanum, Myrrha, Flos Carthami, Herba speranskiae tuberculatae, Radix et Rhizoma Rhei (processed), Dioscorea nipponica Mak. Ningpo Yam Rhizome, Stichopus japonicus, Gekko Swinhonis tail, pyrolusitum etc., the medicinal frozen drying method of above-mentioned raw materials is ground into fine powder, particle diameter is 300-1000 order, make capsule for oral administration, or on-the-spot furnishing paste external application, or external application or take medicine orally simultaneously.The Pyritum that this scheme contains can not informal dress after bone connects, and is unsuitable for the healing completely in bone injury later stage; Contained pyrolusitum can not take for a long time, without the careful clothes of the stagnant person of the stasis of blood, is unsuitable for the treatment in fracture, bone injury later stage.
The inventor is based on drug world working experience for many years, using for reference on the good drug effects of medicine such as GUZHE CUOSHANG JIAONANG, bone setting tablet and the basis of public praise, by to many-sided researchs such as the property of medicine of medical material, drug effects, try hard to find out from Chinese herbal medicine and more can promote union of fracture and instant effect, component simple, clinical practice is good pharmaceutical formulation widely, by experiment and exploration many times, finally successfully develop the present invention.According to the principle of traditional medicine inner disease outer treat, outer sick treatment by oral administration of medicines, the combination of inner and outside, provide a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of cooperation external for oral administration.
Summary of the invention
The object of the invention is to: a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury is provided, and another object is to provide this kind of preparation method for the treatment of the Chinese medicine composition of fracture, bone splits and traumatic injury.
Another object of the present invention is to provide the application of this Chinese medicine composition in a kind of medicine for the treatment of the diseases such as fracture, bone splits and traumatic injury treatment of preparation.
The object of the invention is to be achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury, it is characterized in that, for oral administration and external used medicine, consist of, in described endo-medicine, the parts by weight of various raw materials are: the sub-60-80 part of malleable iron, Radix Angelicae Sinensis 100-150 part, Rhizoma Chuanxiong 100-150 part, Radix Notoginseng 60-120 part, Herba Lycopodii 200-250 part, Rhizoma Drynariae 100-150 part, Radix Dipsaci 100-200 part, Radix Salviae Miltiorrhizae 100-150 part, Rhizoma Corydalis 150-200 part, Radix Rubiae 100-200 part; In external used medicine, the parts by weight of various raw materials are: Sanguis Draxonis 80-120 part, Realgar 80-120 part, Flos Carthami 50-80 part, catechu 80-120 part, cinnabar 50-80 part, Olibanum 60-80 part, Myrrha 70-100 part, Radix Angelicae Sinensis 30-60 part, Rhizoma Paridis 100-200 part, Borneolum Syntheticum 20-30 part, Moschus 5-10 part.
Described a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury, in its endo-medicine, the parts by weight of various crude drug can be preferably: the sub-60-70 part of malleable iron, Radix Angelicae Sinensis 100-120 part, Rhizoma Chuanxiong 100-120 part, Radix Notoginseng 60-100 part, Herba Lycopodii 200-220 part, Rhizoma Drynariae 100-120 part, Radix Dipsaci 100-150 part, Radix Salviae Miltiorrhizae 100-120 part, Rhizoma Corydalis 150-180 part, Radix Rubiae 100-150 part; In external used medicine, the parts by weight of various raw materials can be preferably: Sanguis Draxonis 80-100 part, Realgar 80-100 part, Flos Carthami 50-70 part, catechu 80-100 part, cinnabar 50-70 part, Olibanum 60-70 part, Myrrha 70-90 part, Radix Angelicae Sinensis 30-50 part, Rhizoma Paridis 100-150 part, Borneolum Syntheticum 20-25 part, Moschus 5-10 part.
Further, in the present invention, in endo-medicine, the parts by weight of various raw materials are: 60 parts of malleable iron, 100 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Chuanxiongs, 60 parts of Radix Notoginseng, 200 parts of Herba Lycopodiis, 100 parts of Rhizoma Drynariae, 100 parts of Radix Dipsacis, 100 parts of Radix Salviae Miltiorrhizaes, 150 parts of Rhizoma Corydalis, 100 parts, Radix Rubiae; In external used medicine, the parts by weight of various raw materials are: 80 parts of Sanguis Draxonis, 80 parts of Realgars, 50 parts, Flos Carthami, 80 parts, catechu, 50 parts of cinnabars, 60 parts of Olibanums, 70 parts of Myrrhas, 30 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Paridis, 20 parts of Borneolum Syntheticums, 5 parts, Moschus.
In the crude drug of endo-medicine of the present invention: malleable iron can removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating, antiinflammatory synthetism, what it contained taxi would rather excited autonomic center, promote gastrointestinal peristalsis and appetite, stimulate bone marrow to enliven hematopoietic function, therefore can alleviate aplastic anemia, its strychnine containing has significant analgesic activity and sensoparalysis effect; Radix Angelicae Sinensis has to enrich blood invigorates blood circulation, regulates the effect of body's immunity; Rhizoma Chuanxiong can blood-activating and qi-promoting, dredging collateral is enriched blood, wind-expelling pain-stopping, and its pungent temperature is fragrant dry, walks and does not keep, and can go loosely, and the up top, mountain peak that reaches, enters again blood system, the descending sea of blood that reaches, the various diseases of suitable stagnation of blood stasis; Radix Notoginseng can dissipating blood stasis hemostasis, subduing swelling and relieving pain, promotion hemopoietic, enhancing immunity, and its main effective ingredient is PNS, PDS, PTS and Radix Notoginseng propylhomoserin; Herba Lycopodii can relaxing muscles and tendons and activating QI and blood in the collateral, dehumidifying detumescence, expelling wind and cold, has the effect of cooling, blood pressure lowering; Rhizoma Drynariae can replenishing kidney, strengthening waist, promoting blood circulation and stopping pain, reunion of fractured tendons and bones, to costa sternales dampen or the curative effect of injury of tendon and muscle fracture excellent, for promoting good dose of union of fracture; Radix Dipsaci can the strong muscle of synthetism, has invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous injured, the only effect of metrorrhagia, is usually used in aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, falls and flutter wound, damage muscle folding bone; Radix Salviae Miltiorrhizae can blood circulation promoting and blood stasis dispelling, and removing heat from blood detumescence, nourishing blood to tranquillize the mind, relieving restlessness pain relieving have the effect that promotes organized renewing and regeneration; Rhizoma Corydalis can promoting blood circulation to remove blood stasis, and promoting the circulation of QI to relieve pain have analgesia, calmness, stable effect, are clinical conventional blood-activating analgesic; Radix Rubiae can blood circulation, hemostasia and dissipation blood stasis, can resisting pathogenic microbes, often control traumatic injury congestive edema.
In the crude drug of external used medicine of the present invention: Sanguis Draxonis external can stasis-dispelling and pain-killing, hemostasia and promoting granulation, has antibacterial and effect antiinflammatory, often controls traumatic injury, swelling and pain due to blood stasis, continuous bleeding due to traumatic injury; Realgar can relieving heat toxin, antiinflammatory detumescent, and external has the effect of killing pests and suppressing bacteria; Flos Carthami can promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, can control traumatic injury congestive edema, arthralgia; Catechu can stop blooding analgesic therapy, heat clearing away granulation promoting, can resisting pathogenic microbes, often controls to fall and flutters the pain of injury, traumatic hemorrhage; Cinnabar can tranquilizing mind, heat-clearing and toxic substances removing, it is evil to dispel poison; Olibanum can Repercusion analgesia, antibacterial parasite killing, often controls to fall and flutters injured muscles and bones; Myrrha can break stagnant blood, promoting blood circulation and stopping pain, detumescence and promoting granulation, has antiinflammatory, antibacterial, analgesia and antipyretic effect; Radix Angelicae Sinensis can promoting blood circulation and breaking stagnation, antibacterial pain relieving, has the effect that regulates body's immunity; Rhizoma Paridis can heat-clearing and toxic substances removing, reducing swelling and alleviating pain; Can the heat clearing away loose poison of Borneolum Syntheticum, antibacterial anti-inflammatory, reducing swelling and alleviating pain; Moschus can blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, detumescence and promoting granulation, meridians and collaterals dredging.
Above-mentioned oral medicament composition and externally-applied medicinal composition coordinate jointly, play the effect of blood circulation promoting and enriching, reducing swelling and alleviating pain, reunion of fractured tendons and bones, are highly advantageous to and eliminate swelling and promote growth of spur and wound healing.
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention, is characterized in that, the preparation formulation of described endo-medicine is powder, pill, tablet, capsule, granule, oral liquid.
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention, it is characterized in that, the preparation method of described endo-medicine is: by prescription proportioning, get malleable iron, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Rhizoma Drynariae, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae, ingredients is passed through respectively to screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, then by formula proportion, weigh, fully mix, then be prepared into by conventional method the preparation formulation needing.
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention, is characterized in that, the preparation method of described endo-medicine is:
(1) by Semen Strychni water logging two weeks, scrape peeling, then with Oleum sesami boil to oily foam to the greatest extent, the heart is black crisp thoroughly, deoils, and dries, after weighing by prescription proportioning, pulverizing is standby;
(2) Rhizoma Drynariae is shone after dry doubling unhairing, pulverizing is standby;
(3), after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(4), by the whole mix homogeneously of step (1)-(3) gained medicated powder, store.
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention, is characterized in that, the preparation method of described endo-medicine is on the basis of step (1)-(4), by cold boiled water water and Mel furnishing pill for step (4) gained medicated powder.
A kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention, is characterized in that, the preparation method of described external used medicine is:
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)-(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
The application of a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury of the present invention in the medicine of preparation treatment fracture, bone splits, traumatic injury.
The invention has the beneficial effects as follows: compatibility is reasonable, instant effect, cure rate is high, has no side effect, and is applicable to the treatment of miscellaneous fracture, bone splits and traumatic injury; For oral administration or external can be cured skin and flesh bruise due to soft tissue injury, traumatic injury, dampen back; Fracture, comminuted fracture or bone dislocation position can be effectively treated in cooperation external for oral administration; The situation that with the passing of time comminuted fracture or bone dislocation position do not healed after hospital surgical has good therapeutic effect.
After fracture, edema pain phenomenon must occur, thereby meridian qi and blood heap soil or fertilizer over and around the roots is stagnant obstructed, causes circulatory disturbance, local blood supply situation directly affects union of fracture.So while swelling and ache more very at the fracture initial stage, should focus on circulation of qi promoting, reducing swelling and alleviating pain, eliminating blood stasis to promote regeneration of blood, makes that meridian qi and blood is sensible, circulation is accelerated, increase metabolism, fracture heals in early days.External used medicine of the present invention can reducing swelling and alleviating pain, makes fracture callus hard firmly, repairs at short notice the tissue destroying, and guarantees quick recovery.When fracturing local stasis of bloodization to the greatest extent, meridian qi and blood is unimpeded, and what the pathological changes initial stage showed swells and ache after elimination substantially, and now primary treatment should focus on the reparation of fracture site, motherland's medical science thinks that this type of medicine all returns Liver and kidney two warps, and Liver and kidney two is through having substantial connection to union of fracture.Treat swelling elimination, endo-medicine of the present invention can Bushen Tongluo, reunion of fractured tendons and bones, can excite osteocyte Fast Growth, can make bone connect together fast with osteocyte, can promote vivo oxidation and reduction, and maintain connective tissue normal function, and increase human body fiber and connect, promote wound healing, accelerate blood circulation, accelerate callus and form fast, in bone, be outwards connected and fixed, change therapeutic effect.
Below adopt medicine of the present invention in the main clinical trial example of the diseases such as comminuted fracture, fracture, bone splits and traumatic injury, further to set forth the beneficial effect of medicine of the present invention:
Test example 1 present composition promotes the clinical efficacy of the diseases such as union of fracture
1.1 physical data
Case selection and diagnostic criteria: according to tcm treatment according to syndrome differentiation principle, strictly press in < < disease of tcm Standardization of diagnosis and curative effect ZY/T001.1-94 > > the standard diagnostics about Bone injury disease.
1.2 Therapeutic Method
1.2.1 treatment group: embodiment of the present invention 1-6 gained endo-medicine and external used medicine, according to the usage and dosage administration in symptom concrete condition and embodiment.Endo-medicine the lighter every day 1 time, each 3-4g; Severe one every day 1 time, each 5-6g, 10 days is a course for the treatment of; Till external used medicine is used and is eliminated to affected part swelling.
1.2.2 matched group: GUZHE CUOSHANG JIAONANG, breathe out high-tech Jiamusi pharmaceutical factory of traditional Chinese medicine and manufacture; A 4-6 grain, 3 times on the one, be a course for the treatment of January.
1.2.3 curative effect judging standard: according in < < disease of tcm Standardization of diagnosis and curative effect ZY/T001.1-94 > > about the efficacy assessment standard of Bone injury disease, be divided into clinical cure, improvement, do not heal, three grades judge.Wherein, cure and refer to that symptom and sign disappear, and recover normal on inspection; Improvement refers to that symptom and sign obviously alleviate, and make moderate progress on inspection; More do not refer to that symptom and sign have no improvement, the state of an illness has no improvement.
1.3 clinical data
Treatment group is totally 200 examples, male's 123 examples wherein, women's 77 examples, 10-70 years old ages, 42 years old mean age.
Matched group is totally 200 examples, male's 116 examples wherein, women's 84 examples, 10-70 years old ages, average 46.5 years old.
1.4 observed result
1.4.1 the curative effect for the treatment of group and matched group is in Table 1.
The curative effect comparison sheet of table 1 liang group experiment
Group Number of cases Clinical recovery Take a turn for the better Do not heal Effective percentage (%) Cure rate (%)
Treatment group 200 189 5 4 98 94.5
Matched group 200 141 22 14 83 70.5
As shown in Table 1, treatment group adopts a kind of effective percentage for the treatment of fracture, bone splits, traumatic injury of Chinese medicine composition of the present invention to reach 98%, and cure rate reaches 94.5%, adopts cure rate and the effective percentage of common on the market GUZHE CUOSHANG JIAONANG treatment higher than matched group.
1.4.2 according to the concrete symptom for the treatment of group case be divided into that the fracture of comminuted fracture, bone fracture and dislocation, bone does not misplace, fracture and skin and flesh is broken, dampen back, traumatic injury causes skin and flesh bruise and soft tissue injury, according to clinical observation record and three grades of curative effect judging standards, obtain the total effective rate of every kind of symptom.Treatment group curative effect and Therapeutic Method are in Table 2.
The curative effect of table 2 Chinese medicine composition of the present invention and Therapeutic Method
As seen from the above table, Chinese medicine composition of the present invention to comminuted fracture, bone fracture and dislocation, bone fracture do not misplace, fracture and the not broken situation of skin and flesh adopts the Therapeutic Method that coordinates external for oral administration, total effective rate has reached 95.6%-97.5%; To back dampen, traumatic injury causes skin and flesh bruise and soft tissue injury adopts the Therapeutic Method of for oral administration or external, total effective rate has reached 100%.The Therapeutic Method that employing the present invention treats soft tissue injury, dampen back and traumatic injury causes skin and flesh bruise is for taking orally or external, and treatment time is 1-20 days, 10 days 1 courses for the treatment of ,≤2 courses for the treatment of; Treatment fracture and skin and flesh is broken, Therapeutic Method coordinates external for for oral administration, and treatment time is within 10-40 days, to be 1-4 the course for the treatment of; Treatment comminuted fracture, kindred fracture and dislocation, bone fracture do not misplace, and Therapeutic Method coordinates external for taking orally, and treatment time is 30-60 days, i.e. 3-6 the course for the treatment of.
1.4.3 a kind of curative effect for the treatment of fracture, bone splits for the treatment of group is in Table 3.
A kind of curative effect for the treatment of fracture, bone splits of table 3 the present invention
1.4.4 safety is observed: during medication, toxic and side effects and untoward reaction do not appear in treatment group.
1.5 brief summary
Adopt a kind of fracture, bone splits and traumatic injury disease for the treatment of of medicine of the present invention, treatment group 200 examples, total effective rate reaches 98%, and cure rate reaches 94.5%; Matched group 200 examples, total effective rate is 83%, cure rate is 70.5%; Illustrating that medicine of the present invention has good curative effect, there is untoward reaction and toxic and side effects in none example for the treatment of group 200 examples.
Test example 2 model cases
2.1 Liu so-and-so, man, 25 years old, people from Liuzhi Special Region, Guizhou Province, because traffic accident causes left foot tibia place comminuted fracture, after the operative treatment of being in hospital, doctor informs and need to treat the walking of just leaving the bed for 1 year.Adopt external medicine composition of the present invention, i.e. detumescence completely in 2 days; Take oral medicine of the present invention simultaneously, 1 time every night, within the 10th day, can leave the bed and stand; Continue to take 10 days, the free walking of can leaving the bed in the 20th day.Take after one month, to hospital's check of making film, comminuted fracture heals.
2.2 Zhangs, man, 52 years old, people from Liuzhi Special Region, Guizhou Province, because meet with overturn accident by motorcycle time, right crus of diaphragm fibula place comminuted fracture.Adopt endo-medicine of the present invention to coordinate external medication, recovery from illness afterwards in 30 days, through film making check, comminuted fracture heals, recovers normal.After 1 year, follow up a case by regular visits to, without recurrence.
2.3 weeks so-and-so, female, 65 years old, people from Wuhan City, unfortunate for some reason damage knee, kneecap comminuted fracture into two, knee swelling.To the People's Hospital, treat afterwards, doctor informs the upper draw point of need having an operation, but because knee is swollen too large, must after anti-inflammation detumescence, just can have an operation.Can not subside a swelling yet through 3 day time, operation also therefore delays.Adopt immediately invention endo-medicine to coordinate external medication, in medication i.e. detumescence in the 3rd day, can leaving the bed for the 10th day for the treatment of, stand, at the 20th day, can by bent stick, not walk, within the 30th day, disease is accused recovery from illness.After 1 year, follow up a case by regular visits to, without recurrence.
2.4 kings so-and-so, female, 15 years old, people from Liuzhi Special Region, Guizhou Province, radius place articular fracture, wrist swelling, tenderness are obvious, hands and wrist limitation of activity.Adopt external used medicine of the present invention to apply at fracture, the drug of topical application is 2 times altogether, in recovery from illness in the 30th day for the treatment of.
2.5 soup so-and-so, man, 25 years old, people from Wuhan City, femoral head fracture, does not heal through hospital's conventional therapy for 1 year half, cannot stand, walk about, and takes endo-medicine of the present invention and fully recover after 3 months, femoral head breaking part heals, patient can leave the bed and stand and walk about.After 1 year, follow up a case by regular visits to, without recurrence.
2.6 kings so-and-so, female, 66 years old, people from Wuhan City accidentally fell down downstairs time, causes lumbar vertebra fracture, endlessly, fracture both sides muscular tone, can not stand, and stands up difficulty, is paralyzed in bed for lumbar vertebra local swelling, pain.Adopt endo-medicine of the present invention treatment, during coordinate external used medicine external application 2 times with reducing swelling and alleviating pain, recovery from illness afterwards in 50 days.
The specific embodiment
Embodiment 1
Endo-medicine prescription and method for making:
The sub-60g of malleable iron, Radix Angelicae Sinensis 100g, Rhizoma Chuanxiong 100g, Radix Notoginseng 60g, Herba Lycopodii 200g, Rhizoma Drynariae 100g, Radix Dipsaci 100g, Radix Salviae Miltiorrhizae 100g, Rhizoma Corydalis 150g, Radix Rubiae 100g;
(1) by Semen Strychni water logging two weeks, scrape peeling, then with Oleum sesami boil to oily foam to the greatest extent, the heart is black crisp thoroughly, deoils, and dries, after weighing by prescription proportioning, pulverizing is standby;
(2) Rhizoma Drynariae is shone after dry doubling unhairing, pulverizing is standby;
(3), after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(4) by the whole mix homogeneously of step (1)-(3) gained medicated powder, store and obtain powder.
External used medicine prescription and method for making:
Sanguis Draxonis 80g, Realgar 80g, Flos Carthami 50g, catechu 80g, cinnabar 50g, Olibanum 60g, Myrrha 70g, Radix Angelicae Sinensis 30g, Rhizoma Paridis 100g, Borneolum Syntheticum 20g, Moschus 5g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 1 time, each 3~6g, takes with rice wine;
Medicine for external use, with to detumescence, changed one time medicine every 5~10 days, during use, Chinese medicinal powder and mature vinegar are mixed well as paste, will hinder swollen place and all apply good wrapping.
Embodiment 2
Endo-medicine prescription and method for making:
The sub-80g of malleable iron, Radix Angelicae Sinensis 150g, Rhizoma Chuanxiong 150g, Radix Notoginseng 120g, Herba Lycopodii 250g, Rhizoma Drynariae 150g, Radix Dipsaci 200g, Radix Salviae Miltiorrhizae 150g, Rhizoma Corydalis 200g, Radix Rubiae 200g;
(1) by Semen Strychni water logging two weeks, scrape peeling, then with Oleum sesami boil to oily foam to the greatest extent, the heart is black crisp thoroughly, deoils, and dries, after weighing by prescription proportioning, pulverizing is standby;
(2) Rhizoma Drynariae is shone after dry doubling unhairing, pulverizing is standby;
(3), after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(4) by the whole mix homogeneously of step (1)-(3) gained medicated powder, store standby;
(5) by cold boiled water water and Mel furnishing pill for step (4) gained medicated powder.Specification: 1g/ ball.
External used medicine prescription and method for making:
Sanguis Draxonis 120g, Realgar 120g, Flos Carthami 80g, catechu 120g, cinnabar 80g, Olibanum 80g, Myrrha 100g, Radix Angelicae Sinensis 60g, Rhizoma Paridis 200g, Borneolum Syntheticum 30g, Moschus 10g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 1 time, each 3~6 balls, warm water takes;
Medicine for external use, with to detumescence, changed one time medicine every 5~10 days, during use, Chinese medicinal powder and mature vinegar are mixed well as paste, will hinder swollen place and all apply good wrapping.
Embodiment 3
Endo-medicine prescription and method for making:
The sub-70g of malleable iron, Radix Angelicae Sinensis 120g, Rhizoma Chuanxiong 120g, Radix Notoginseng 100g, Herba Lycopodii 220g, Rhizoma Drynariae 120g, Radix Dipsaci 150g, Radix Salviae Miltiorrhizae 120g, Rhizoma Corydalis 180g, Radix Rubiae 150g;
Get above-mentioned medical material, pass through respectively screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, then by formula proportion, weigh, fully mix, then add starch 1:1 and mix, crushed after being dried becomes fine powder, sieve, 85% the ethanol of take is wetting agent, granule processed, and 60-70 ℃ is dry, add 2% Pulvis Talci and evenly mix, be pressed into tablet.Specification: 0.5g/ sheet.
External used medicine prescription and method for making:
Sanguis Draxonis 100g, Realgar 100g, Flos Carthami 70g, catechu 100g, cinnabar 70g, Olibanum 70g, Myrrha 90g, Radix Angelicae Sinensis 50g, Rhizoma Paridis 150g, Borneolum Syntheticum 25g, Moschus 8g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 2 times, each 3~6;
Medicine for external use, with to detumescence, changed one time medicine every 5~10 days, during use, Chinese medicinal powder and mature vinegar are mixed well as paste, will hinder swollen place and all apply good wrapping.
Embodiment 4
Endo-medicine prescription and method for making:
The sub-70g of malleable iron, Radix Angelicae Sinensis 110g, Rhizoma Chuanxiong 130g, Radix Notoginseng 80g, Herba Lycopodii 230g, Rhizoma Drynariae 130g, Radix Dipsaci 130g, Radix Salviae Miltiorrhizae 130g, Rhizoma Corydalis 170g, Radix Rubiae 130g;
Get above-mentioned medical material, pass through respectively screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, then by formula proportion, weigh, fully mix, incapsulate, obtain capsule.Specification: 0.5g/ grain.
External used medicine prescription and method for making:
Sanguis Draxonis 110g, Realgar 110g, Flos Carthami 60g, catechu 110g, cinnabar 60g, Olibanum 70g, Myrrha 90g, Radix Angelicae Sinensis 60g, Rhizoma Paridis 130g, Borneolum Syntheticum 20g, Moschus 7g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 3 times, each 2~4, warm water takes;
Embodiment 5
Endo-medicine prescription and method for making:
The sub-60g of malleable iron, Radix Angelicae Sinensis 100g, Rhizoma Chuanxiong 100g, Radix Notoginseng 60g, Herba Lycopodii 200g, Rhizoma Drynariae 100g, Radix Dipsaci 100g, Radix Salviae Miltiorrhizae 100g, Rhizoma Corydalis 150g, Radix Rubiae 100g;
Get above-mentioned pulverizing medicinal materials and become coarse powder, then add 12 times of water gagings and soak 0.5 hour, water decocts 4 times, and each 0.5 hour, filter, merging filtrate is evaporated to the thick paste that relative density is 1.15-1.30 under 80 ℃ of conditions; Get above-mentioned thick paste, add dextrin, cane sugar powder or lactose appropriate, mix, add clear paste and granulate, dry, granulation agent.Specification: 10g/ bag.
External used medicine prescription and method for making:
Sanguis Draxonis 80g, Realgar 80g, Flos Carthami 50g, catechu 80g, cinnabar 50g, Olibanum 60g, Myrrha 70g, Radix Angelicae Sinensis 30g, Rhizoma Paridis 100g, Borneolum Syntheticum 20g, Moschus 6g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 3 times, each 10g, boiled water is taken after mixing it with water;
Medicine for external use, with to detumescence, changed one time medicine every 5~10 days, during use, Chinese medicinal powder and mature vinegar are mixed well as paste, will hinder swollen place and all apply good wrapping.
Embodiment 6
Endo-medicine prescription and method for making:
The sub-70g of malleable iron, Radix Angelicae Sinensis 110g, Rhizoma Chuanxiong 110g, Radix Notoginseng 70g, Herba Lycopodii 210g, Rhizoma Drynariae 110g, Radix Dipsaci 120g, Radix Salviae Miltiorrhizae 110g, Rhizoma Corydalis 160g, Radix Rubiae 110g;
Get above-mentioned pulverizing medicinal materials and become coarse powder, then add 5 times of water gagings and soak 4 hours, water decocts 4 hours, filters, and is evaporated to the thick paste that relative density is 1.05-1.20 under 50 ℃ of conditions; Get above-mentioned thick paste, under agitation adding ethanol, to make containing alcohol amount be 70%, standing 24 hours, filter, concentrated, concentrated after simple syrup add to sugar content 10%, add 0.2 minute sodium benzoate, boil dissolving, adding distil water, to full dose, mixes, and filters, oral liquid is made in embedding.10ml/ props up.
External used medicine prescription and method for making:
Sanguis Draxonis 90g, Realgar 90g, Flos Carthami 60g, catechu 90g, cinnabar 60g, Olibanum 70g, Myrrha 80g, Radix Angelicae Sinensis 40g, Rhizoma Paridis 110g, Borneolum Syntheticum 25g, Moschus 9g;
(1) Sanguis Draxonis, Realgar, catechu, cinnabar, Borneolum Syntheticum, Moschus are weighed by prescription proportioning respectively, pulverizing is standby;
(2) Flos Carthami, Radix Angelicae Sinensis, Rhizoma Paridis are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(3) by wick for Olibanum and Myrrha with frying, remove Medulla Junci after pulverizing standby;
(4) by the whole mix homogeneously of step (1)~(3) gained medicated powder, sealed type storage is in porcelain vase;
(5) while using, the medicated powder in step (4) is mixed well into externally used paste with mature vinegar.
Usage and dosage:
Oral medicine every day 3 times, each 10ml;
Medicine for external use, with to detumescence, changed one time medicine every 5~10 days, during use, Chinese medicinal powder and mature vinegar are mixed well as paste, will hinder swollen place and all apply good wrapping.

Claims (8)

1. a Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury, it is characterized in that, for oral administration and external used medicine, consist of, in described endo-medicine, the parts by weight of various crude drug are: Semen Strychni 60-80 part, Radix Angelicae Sinensis 100-150 part, Rhizoma Chuanxiong 100-150 part, Radix Notoginseng 60-120 part, Herba Lycopodii 200-250 part, Rhizoma Drynariae 100-150 part, Radix Dipsaci 100-200 part, Radix Salviae Miltiorrhizae 100-150 part, Rhizoma Corydalis 150-200 part, Radix Rubiae 100-200 part; In external used medicine, the parts by weight of various crude drug are: Sanguis Draxonis 80-120 part, Realgar 80-120 part, Flos Carthami 50-80 part, catechu 80-120 part, cinnabar 50-80 part, Olibanum 60-80 part, Myrrha 70-100 part, Radix Angelicae Sinensis 30-60 part, Rhizoma Paridis 100-200 part, Borneolum Syntheticum 20-30 part, Moschus 5-10 part.
2. a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury according to claim 1, it is characterized in that, in described endo-medicine, the parts by weight of various crude drug are: Semen Strychni 60-70 part, Radix Angelicae Sinensis 100-120 part, Rhizoma Chuanxiong 100-120 part, Radix Notoginseng 60-100 part, Herba Lycopodii 200-220 part, Rhizoma Drynariae 100-120 part, Radix Dipsaci 100-150 part, Radix Salviae Miltiorrhizae 100-120 part, Rhizoma Corydalis 150-180 part, Radix Rubiae 100-150 part; In external used medicine, the parts by weight of various crude drug are: Sanguis Draxonis 80-100 part, Realgar 80-100 part, Flos Carthami 50-70 part, catechu 80-100 part, cinnabar 50-70 part, Olibanum 60-70 part, Myrrha 70-90 part, Radix Angelicae Sinensis 30-50 part, Rhizoma Paridis 100-150 part, Borneolum Syntheticum 20-25 part, Moschus 5-10 part.
3. a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury according to claim 1, it is characterized in that, in described endo-medicine, the parts by weight of various crude drug are: 60 parts of Semen Strychni, 100 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Chuanxiongs, 60 parts of Radix Notoginseng, 200 parts of Herba Lycopodiis, 100 parts of Rhizoma Drynariae, 100 parts of Radix Dipsacis, 100 parts of Radix Salviae Miltiorrhizaes, 150 parts of Rhizoma Corydalis, 100 parts, Radix Rubiae; In external used medicine, the parts by weight of various crude drug are: 80 parts of Sanguis Draxonis, 80 parts of Realgars, 50 parts, Flos Carthami, 80 parts, catechu, 50 parts of cinnabars, 60 parts of Olibanums, 70 parts of Myrrhas, 30 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Paridis, 20 parts of Borneolum Syntheticums, 5 parts, Moschus.
4. according to a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury described in claim 1-3 any one, it is characterized in that, the preparation formulation of described endo-medicine is powder, pill, tablet, capsule, granule, oral liquid.
5. according to a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury described in claim 1-3 any one, it is characterized in that, the preparation method of described endo-medicine is: by prescription proportioning, get Semen Strychni, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Rhizoma Drynariae, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae, ingredients is passed through respectively to screening, the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, then by formula proportion, weigh, fully mix, then be prepared into by conventional method the preparation formulation needing.
6. according to a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury described in claim 1-3 any one, it is characterized in that, the preparation method of described endo-medicine is:
(1) by Semen Strychni water logging two weeks, scrape peeling, then with Oleum sesami boil to oily foam to the greatest extent, the heart is black crisp thoroughly, deoils, and dries, after weighing by prescription proportioning, pulverizing is standby;
(2) Rhizoma Drynariae is shone after dry doubling unhairing, pulverizing is standby;
(3), after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Notoginseng, Herba Lycopodii, Radix Dipsaci, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Radix Rubiae are weighed by prescription proportioning respectively, dry, pulverizing is standby;
(4), by the whole mix homogeneously of step (1)-(3) gained medicated powder, store.
7. a kind of Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury according to claim 6, it is characterized in that, the preparation method of described endo-medicine is on the basis of step (1)-(4), by cold boiled water water and Mel furnishing pill for step (4) gained medicated powder.
8. the application of the Chinese medicine composition for the treatment of fracture, bone splits and traumatic injury according to a kind of described in claim 1-3 any one in the medicine of preparation treatment fracture, bone splits, traumatic injury.
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CN104435768A (en) * 2014-09-22 2015-03-25 刘德刚 Traditional Chinese medicine for treating injuries from falls, fractures, contusions and strains
CN105106659A (en) * 2015-09-29 2015-12-02 吴建国 Traditional Chinese medicine composition for promoting healing of bone fracture
CN105106521A (en) * 2015-10-16 2015-12-02 韩守江 Analgesic for traumatic injuries
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