CN103623091B - Medicament for external use for treating gout - Google Patents

Medicament for external use for treating gout Download PDF

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Publication number
CN103623091B
CN103623091B CN201310655701.4A CN201310655701A CN103623091B CN 103623091 B CN103623091 B CN 103623091B CN 201310655701 A CN201310655701 A CN 201310655701A CN 103623091 B CN103623091 B CN 103623091B
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China
Prior art keywords
powder
medicament
parts
gout
chinese medicine
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CN201310655701.4A
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CN103623091A (en
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刘泽梅
王淑艳
于鹏
武瑞美
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Liu Zemei
Wang Shuyan
Wu Ruimei
Yu Peng
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Individual
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Abstract

The invention discloses a medicament for external use for treating gout. The medicament for external use is characterized by being powder, wherein the powder is used for lavipeditum and is prepared from the following traditional Chinese medicine raw materials in parts by weight: 1-3 parts of sanguisorba officinalis, 1-3 parts of sageretia theezans roots, 1-3 parts of platycladus orientalis, 1-3 parts of masson pine peels, 1-3 parts of herba cirsii and 0.25-0.75 part of borneol. The medicament for external use disclosed by the invention is convenient to use and safe, does not have toxic and side effects and has a better therapeutic effect on the gout; the powder is low in cost, economical and practical, and a patient can easily afford the lavipeditum powder; due to the method for treating the internal illness by external treatment, the infected part is treated in a warm bath through the lavipeditum powder; part of the medicament can be absorbed through the skin; the effective concentration of part of the medicament is remarkably higher than the concentration of blood, so that the outstanding therapeutic effect is achieved.

Description

A kind of external used medicine being used for the treatment of gout
Technical field
The present invention relates to a kind of medicine being used for the treatment of gout, a kind of lavipeditum powder especially wherein.
Background technology
Gout, also known as " hyperuricemia ", is a kind of because of disorders of purine metabolism, makes the synthesis of uric acid increase or discharge and reduces, cause hyperuricemia, thus the disease caused, belong to arthritic one, also known as metabolic arthritis.Due to uric acid excessive concentration in blood of human body, at soft tissue as formed acicular crystal in membrana articulata or tendon, causing body immune system overreaction and the inflammation caused suffering, causing the foreign body inflammatory reaction of tissue.General outbreak position mostly is large female toe joint, ankle joint and knee joint etc.Gouty attack,acute position occur red, swollen, hot, have an intense pain, much more general to show effect midnight, people can be made to wake up with a start from sleep; At the gout initial stage, lower limb are more common in outbreak.According to statistics, gout patients 20% ~ 25% has urate nephropathy, and person is almost 100% nephropathy; Kidney damage comprises gouty nephropathy, acute obstructive nephropathy and lithangiuria.Goat, at any age, can occur, and modal is the middle-aged man of more than 40 years old.
Along with the raising of people's living standard, irrational dietary structure and faster work rhythm, the sickness rate of gout is the trend of cumulative year after year.But up to now, clinical treatment gout first-selection or colchicine, its dose therapeutically effective easily causes serious gastrointestinal reaction.
Therefore, a kind of efficient, convenient, bland gout medicine for external use of exploitation, has the urgency of clinical demand.Chinese medicine external treatment gout is effective, obtains clinical affirmative, and medicine source is abundant, side effect is little.Therefore, screen effective Chinese medicine, form new exterior-applied formulation in conjunction with modern novel adjuvant, will wide potential applicability in clinical practice be had.
Summary of the invention
Task of the present invention is to provide a kind of external used medicine being used for the treatment of gout.
Being used for the treatment of an external used medicine for gout, is the powder for foot bath be made up of the raw material of Chinese medicine by following parts by weight:
Radix Sanguisorbae 1 ~ 3 part, Sageretia theezans root 1 ~ 3 part, Cacumen Platycladi 1 ~ 3 part, horse hair Cortex Pini Massonianae 1 ~ 3 part, Herba Cirsii 1 ~ 3 part, Borneolum Syntheticum 0.25 ~ 0.75 part.
By above-mentioned Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii parch to black; After raw material of Chinese medicine after parch to black and Borneolum Syntheticum are ground to form powdery respectively, mix homogeneously makes powder, or grinds to form powdery after being mixed with Borneolum Syntheticum by the raw material of Chinese medicine after parch to black and make powder.
Pharmacology analysis:
Radix Sanguisorbae in the present invention, another name claims Fructus Cucumidis sativi cus-cus, mountain Radix Fici tikouae, whip Fructus Jujubae beard etc., records, have cooling blood for hemostasis, effect of astringing to arrest diarrhea according to China's pharmacopeia.Sageretia theezans (Sageretia theezans), according to the record of " Chinese Plants will " (Science Press, 1982), is Rhamnaceae, rattan shape or upright shrub; Sprig tool stings, alternate or near to life, and brown, by pubescence; Originate in Yangtze River in China basin and southeastern coast each province, also there are distribution in Japan and India, are subtropical zone preferential species of tree; Sageretia theezans root, has the effects such as lowering the adverse-rising QI to resolve phlegm, wind-damp dispelling, benefit muscles and bones, can treat the diseases such as scabies, edema, the arthroncus of knee.Cacumen Platycladi, another name claims Cacumen Platycladi (Cacumen Biotae), Cong Baiye, arborvitae, flat pine etc., has removing heat from blood, hemostasis, wind-damp dispelling, loose effect swollen and ache.Horse hair Cortex Pini Massonianae, the i.e. dry bark of Pinus massoniana Lamb, have wind-damp dispelling, blood circulation promoting and blood stasis dispelling, pain relieving, hemostasis, loose effect swollen and ache.Herba Cirsii, another name claims field thistle, luxuriant dish, shepherd's purse shepherd's purse hair etc., has cooling blood for hemostasis, the effect of strongly fragrant detumescence of dispelling.Borneolum Syntheticum, has effect of refreshment of having one's ideas straightened out, loose stagnated fire, reducing swelling and alleviating pain.
External used medicine of the present invention is easy to use, safe, have no side effect, there is good curative effect to gout, and use powder, with low cost, economical and practical, patient is acceptant, uses lavipeditum powder, adopts the method for inner disease outer treat, treat with lavipeditum powder temperature bath affected part, absorb by skin, make topical remedy's valid density be significantly higher than haemoconcentration, thus play significant curative effect.
Detailed description of the invention
Powder means that one or several medicines are through pulverizing and mixing homogeneously and the powder preparation made.The advantage of powder, specific surface area is comparatively large, easily disperses, and proves effective very fast; Preparation is simple, and be suitable for hospital preparation, the utilization of Chinese powder medicine has huge advantage.Be mainly manifested in: 1. powder is easy to use, directly can be taken after being infused in hot water or decoction with boiled water, be applicable to the rhythm of life of modern society; 2., after powder carries out point packaging, dosage is accurate, easy to carry, is convenient to user and better controls taking dose; 3., compared with the decoction of same prescription, the single dosage of patient reduces, and the producing level of medical material is higher, more " saving " medical material; 4., compared with decoction, chronic's life-time service is more suitable for, less to gastrointestinal effects relative to decoction, be not easy the appetite and the digestive function that affect user.
Embodiment 1
Take Radix Sanguisorbae 100g, Sageretia theezans root 100g, Cacumen Platycladi 100g, horse hair Cortex Pini Massonianae 100g, Herba Cirsii 100g, Borneolum Syntheticum 25g.
By above-mentioned each component raw material of Chinese medicine, as Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii, respectively parch to black, to grind to form after powdery by setting weight part than mix homogeneously, the powder for foot bath made respectively by the raw material of Chinese medicine after above-mentioned parch to black and Borneolum Syntheticum.
Embodiment 2
Take Radix Sanguisorbae 200g, Sageretia theezans root 200g, Cacumen Platycladi 200g, horse hair Cortex Pini Massonianae 200g, Herba Cirsii 200g, Borneolum Syntheticum 50g.
By above-mentioned each component raw material of Chinese medicine, as Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii, respectively parch to black, to grind to form after powdery by setting weight part than mix homogeneously, the powder for foot bath made respectively by the raw material of Chinese medicine after above-mentioned parch to black and Borneolum Syntheticum.
Embodiment 3
Take Radix Sanguisorbae 300g, Sageretia theezans root 300g, Cacumen Platycladi 300g, horse hair Cortex Pini Massonianae 300g, Herba Cirsii 300g, Borneolum Syntheticum 75g.
By above-mentioned each component raw material of Chinese medicine, as Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii, respectively parch to black, to grind to form after powdery by setting weight part than mix homogeneously, the powder for foot bath made respectively by the raw material of Chinese medicine after above-mentioned parch to black and Borneolum Syntheticum.
Embodiment 4
Take Radix Sanguisorbae 100g, Sageretia theezans root 200g, Cacumen Platycladi 100g, horse hair Cortex Pini Massonianae 200g, Herba Cirsii 100g, Borneolum Syntheticum 25g.
By above-mentioned each component raw material of Chinese medicine, as Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii mixing parch to black, by the raw material of Chinese medicine after above-mentioned parch to black and Borneolum Syntheticum mixed grinding powdering, the powder for foot bath made.
Embodiment 5
Take Radix Sanguisorbae 300g, Sageretia theezans root 100g, Cacumen Platycladi 300g, horse hair Cortex Pini Massonianae 100g, Herba Cirsii 200g, Borneolum Syntheticum 75g.
By above-mentioned each component raw material of Chinese medicine, as Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii mixing parch to black, by the raw material of Chinese medicine after above-mentioned parch to black and Borneolum Syntheticum mixed grinding powdering, the powder for foot bath made.
Clinical data:
The present invention for traditional Chinese medical science gout, through 100 routine clinical observations.Select tcm diagnosis gout to be standard: patient has hyperuricemia, often in midnight joint have an intense pain, joint is red, swollen, hot at ordinary times, bitterly, limitation of activity, articular cavity has hydrops, occurs that tophus precipitates.As there is above-mentioned symptom, can make a definite diagnosis.In the case making a definite diagnosis observation, male accounts for 64 examples, and women accounts for 36 examples, and without other serious diseases, the age, the mean age was 50.2 years old between 40 ~ 65 years old.
Efficacy determination:
1. effective: body constitution strengthens, with it energetically; Hyperuricemia is controlled, and red, swollen, hot, the pain in joint are obviously alleviated; Hydrarthrosis reduces.
2. effective: body constitution strengthens, with it energetically; Red, swollen, hot, the pain in joint alleviate to some extent.
3. invalid: disease is unchanged.
During clinical trial, stop using other drug and health nutrient.
Therapeutic Method: pour in foot bathing basin by powder 20 ~ 50g of the present invention, add appropriate hot water (about 60 DEG C is good), water was as the criterion to expire ankle, then foot bath about 30 ~ 60 minutes.
Therapeutic effect: curing number is 56 examples, and significant figure is 38 examples, and invalid number is 6 examples, and total effective rate reaches 94%.There are no toxic and side effects in therapeutic process, there is good curative effect to obstinate patient.
For further illustrating therapeutic effect, now enumerate model case as follows:
Patient 1: certain man, 40 years old, suffers from gout 3 years, and partial joint is red, swollen, bitterly.Treat with powder temperature bath of the present invention, every day 2 times, above symptom is alleviated for 10 days, within 30 days, eliminates.Pay a return visit without recurrence after 6 months.
Patient 2: certain female, 52 years old, suffer from the gout several years, brothers' cold type of pain, articular pain.Once took the Chinese medicine of multiple treatment gout, but effect is all not good.Treat with powder temperature bath of the present invention, every day 2 times, above symptom is alleviated for 6 days, within 15 days, eliminates.Pay a return visit without recurrence after 6 months.
Patient 3: certain man, 65 years old, suffer from gout many decades, whole body membra arthralgia, moving difficulty.Treat with powder temperature bath of the present invention, every day 2 times, above symptom is alleviated for 6 days, within 15 days, eliminates.Pay a return visit without recurrence after 6 months.
The relevant technologies content do not addressed in aforesaid way is taked or uses for reference prior art to realize.
It should be noted that, under the instruction of this description, those skilled in the art can also make such or such easy variation pattern, such as equivalent way, or obvious mode of texturing.Above-mentioned variation pattern all should within protection scope of the present invention.

Claims (1)

1. be used for the treatment of an external used medicine for gout, it is characterized in that the powder for foot bath be made up of the raw material of Chinese medicine by following parts by weight:
Radix Sanguisorbae 1 ~ 3 part, Sageretia theezans root 1 ~ 3 part, Cacumen Platycladi 1 ~ 3 part, horse hair Cortex Pini Massonianae 1 ~ 3 part, Herba Cirsii 1 ~ 3 part, Borneolum Syntheticum 0.25 ~ 0.75 part;
By above-mentioned Radix Sanguisorbae, Sageretia theezans root, Cacumen Platycladi, horse hair Cortex Pini Massonianae, Herba Cirsii parch to black; After raw material of Chinese medicine after parch to black and Borneolum Syntheticum are ground to form powdery respectively, mix homogeneously makes powder, or grinds to form powdery after being mixed with Borneolum Syntheticum by the raw material of Chinese medicine after parch to black and make powder.
CN201310655701.4A 2013-12-04 2013-12-04 Medicament for external use for treating gout Expired - Fee Related CN103623091B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1544068A (en) * 2002-09-05 2004-11-10 �Ϻ���ͨ��ѧ Antigout medicinal composition and its preparing method
CN101474271A (en) * 2008-12-26 2009-07-08 耿顺安 Medicament for treating uarthritis
CN103100010A (en) * 2013-02-19 2013-05-15 武瑞美 Drug for treatment of rheumatic arthritis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1544068A (en) * 2002-09-05 2004-11-10 �Ϻ���ͨ��ѧ Antigout medicinal composition and its preparing method
CN101474271A (en) * 2008-12-26 2009-07-08 耿顺安 Medicament for treating uarthritis
CN103100010A (en) * 2013-02-19 2013-05-15 武瑞美 Drug for treatment of rheumatic arthritis

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Inventor after: Wang Shuyan

Inventor after: Yu Peng

Inventor after: Wu Ruimei

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Address after: 266400 Huangdao District Second Hospital of traditional Chinese medicine, 1 Zhongyuan street, Huangdao District, Shandong, Qingdao

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Applicant after: Liu Zemei

Applicant after: Wang Shuyan

Applicant after: Yu Peng

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