CN102688401B - Traditional Chinese medicine oral liquid of couch grass root for treating chronic hepatitis and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid of couch grass root for treating chronic hepatitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine oral liquid of couch grass root for treating chronic hepatitis, comprising the following traditional Chinese medicine raw materials in parts by weight: 90-180 parts of couch grass root, 90-180 parts of virgate wormwood herb, 30-90 parts of largehead atractylodes rhizome, 30-90 parts of ginger pinellia, 30-90 parts of bupleurum, 90-180 parts of radix rehmanniae, 30-90 parts of pseudo-ginseng, 30-90 parts of earthworm and 30-60 parts of liquorice. The traditional Chinese medicine preparation disclosed by the invention can eliminate qi movement stasis of liver and gall, alleviate harm to liver, normalize the function of choleresis and biliary excretion and take the effects of strengthening the body resistance without stasis of pathogenic factor and eliminating pathogenic factor without hurt to the body resistance. The oral liquid has low cost and is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine product, relate in particular to a kind of chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid and preparation method thereof that is used for the treatment of.
Background technology
Chronic hepatitis refers to and caused by different pathogeny, and the course of disease at least continues to surpass hepatic necrosis and the inflammation more than 6 months, can have clinically corresponding symptom, sign regulating liver-QI biochemical analysis abnormal, also can, without obvious clinical symptoms, necrosis and the inflammation of hepatic tissue only be arranged.The course of disease is undulatory property or continues carrying out property, and if do not carried out suitable treatment, some patients were can make progress as liver cirrhosis.Chronic hepatitis is light, moderate: the early symptom of typical chronic hepatitis is slight and lack specificity, is the undulatory property intermittence, even for many years without any symptom.Modal is exactly easy fatigue and stomach discomfort, easily is left in the basket, and also easily being mistaken as is gastropathy; Often see clinically invisible liver cirrhosis patient, before liver cirrhosis occurring, do not feel significant discomfort, also do not carry out conventional health check-up, progressively develop into liver cirrhosis unconsciously; Occasionally there is the patient to occur feeling sick, abdominal distention, jaundice, the urine color depth, chronic hepatitis is because hepatocyte is destroyed, and liver function is repeatedly abnormal, causes protracted inflammation more or repeatedly not show effect, still lack at present effective treatment means, all caused very large misery to patient's physiology and psychology, had a strong impact on patient's quality of life, and patient's life is threatened.It is that side effect is large that there is disadvantage in the medication of western medicine chronic hepatitis disease, the patient is had to very large injury, and traditional Chinese medical science Chinese herbal medicine oneself by universally acknowledged be the precious treasure-houses of indispensable mankind medicine, adopt the means of Chinese medicine to treat the chronic hepatitis disease, it is a channel extremely leaved for development, the characteristics such as it is gentle that Chinese medicine has the property of medicine, applied widely, have its original effect as chronic hepatitis disease treatment aspect.
Summary of the invention
The purpose of this invention is to provide a kind of curative effect lasting, treating both the principal and secondary aspects of a disease, treatment chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid that cost is low and preparation method thereof.
For achieving the above object, the present invention is achieved by the following technical solutions:
Technical scheme of the present invention is: treatment chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid is that the raw material of Chinese medicine by following weight portion is prepared from:
Rhizoma Imperatae 90-180 part, Herba Artemisiae Scopariae 90-180 part, Rhizoma Atractylodis Macrocephalae 30-90 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 30-90 part, Radix Bupleuri 30-90 part, Radix Rehmanniae 90-180 part, Radix Notoginseng 30-90 part, Pheretima 30-90 part, Radix Glycyrrhizae 30-60 part.
Described treatment chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid is that the raw material of Chinese medicine by following weight portion is prepared from:
180 parts of Rhizoma Imperataes, 180 parts of Herba Artemisiae Scopariaes, 90 parts of the Rhizoma Atractylodis Macrocephalaes, 90 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 90 parts of Radix Bupleuri, 180 parts of Radix Rehmanniae, 90 parts of Radix Notoginseng, 90 parts of Pheretimas, 60 parts, Radix Glycyrrhizae.
The preparation method of described treatment chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid, concrete steps are as follows
Get 180 parts of Rhizoma Imperataes, 180 parts of Herba Artemisiae Scopariaes, 90 parts of the Rhizoma Atractylodis Macrocephalaes, 90 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 90 parts of Radix Bupleuri, 180 parts of Radix Rehmanniae, 90 parts of Radix Notoginseng, 90 parts of Pheretimas, 60 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into the clear paste of surveying relative density 1.10-1.25 at 60-65 ℃, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Usage and consumption: oral, each 20 milliliters of medicine of the present invention, every day 3 times, half an hour, 3 months be a course for the treatment of after meal.
In raw material of Chinese medicine of the present invention, Rhizoma Imperatae: sweet, cold, return lung, stomach, urinary bladder channel, cooling blood for hemostasis, clearing away heat and promoting diuresis; Herba Artemisiae Scopariae: bitter, hot, be slightly cold, return spleen, stomach, liver, gallbladder meridian, clearing away damp-heat, jaundice eliminating subcutaneous ulcer, for jaundice oliguria, eczema pruritus, infectious jaundice type hepatitis; The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp, air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): hot, temperature, poisonous, return spleen, stomach, lung meridian, stopping nausea and vomiting by lowering the adverse flow of QI, for vomitting, regurgitation, breast gastral cavity painful abdominal mass are vexed, globus hystericus; Radix Bupleuri: bitter, be slightly cold, return Liver Channel, gallbladder meridian, evacuate bring down a fever, yang invigorating soothing liver-QI, cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus come off, menoxenia; Radix Rehmanniae: sweet, bitter, cold, GUIXIN, liver, kidney channel, clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Pheretima: cold, salty, enter Liver Channel, spleen channel, urinary bladder channel, clearing heat for calming endogenous wind, dredging collateral, relieving asthma, diuresis: Radix Notoginseng: sweet, micro-hardship, temperature, GUIXIN, liver, spleen channel, removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation; Radix Glycyrrhizae: sweet, flat, GUIXIN, spleen, lung, stomach warp, invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, alleviation pain relieving, the mitigation property of medicine; All medicines are the merit of long memorial liver promoting the function of the gallbladder to alleviate jaundice, activating blood circulation to dissipate blood stasis, dredging collateral nourishing the liver altogether, and Chinese medicine preparation of the present invention is eliminated the liver and gall depression and stagnation of QI, alleviates liver injury, make bile secretion and excretory function recover normal, play the not stagnant heresy of righting, eliminating evilly do not hinder positive effect, cost is low, and clinic is applied.
The specific embodiment
Embodiment 1:
Raw material of Chinese medicine: 180 parts of Rhizoma Imperataes, 180 parts of Herba Artemisiae Scopariaes, 90 parts of the Rhizoma Atractylodis Macrocephalaes, 90 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 90 parts of Radix Bupleuri, 180 parts of Radix Rehmanniae, 90 parts of Radix Notoginseng, 90 parts of Pheretimas, 60 parts, Radix Glycyrrhizae.
Method for making: get 180 parts of Rhizoma Imperataes, 180 parts of Herba Artemisiae Scopariaes, 90 parts of the Rhizoma Atractylodis Macrocephalaes, 90 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 90 parts of Radix Bupleuri, 180 parts of Radix Rehmanniae, 90 parts of Radix Notoginseng, 90 parts of Pheretimas, 60 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into the clear paste of surveying relative density 1.10-1.25 at 60-65 ℃, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 2:
Raw material of Chinese medicine: 135 parts of Rhizoma Imperataes, 135 parts of Herba Artemisiae Scopariaes, 60 parts of the Rhizoma Atractylodis Macrocephalaes, 60 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 60 parts of Radix Bupleuri, 135 parts of Radix Rehmanniae, 60 parts of Radix Notoginseng, 60 parts of Pheretimas, 40 parts, Radix Glycyrrhizae.
Method for making: get 135 parts of Rhizoma Imperataes, 135 parts of Herba Artemisiae Scopariaes, 60 parts of the Rhizoma Atractylodis Macrocephalaes, 60 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 60 parts of Radix Bupleuri, 135 parts of Radix Rehmanniae, 60 parts of Radix Notoginseng, 60 parts of Pheretimas, 40 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into the clear paste of surveying relative density 1.10-1.25 at 60-65 ℃, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 3:
Raw material of Chinese medicine: 90 parts of Rhizoma Imperataes, 90 parts of Herba Artemisiae Scopariaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 30 parts of Radix Bupleuri, 90 parts of Radix Rehmanniae, 30 parts of Radix Notoginseng, 30 parts of Pheretimas, 30 parts, Radix Glycyrrhizae.
Method for making: get 90 parts of Rhizoma Imperataes, 90 parts of Herba Artemisiae Scopariaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 30 parts of Radix Bupleuri, 90 parts of Radix Rehmanniae, 30 parts of Radix Notoginseng, 30 parts of Pheretimas, 30 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each l-2 hour, filter, filtrate is condensed into the clear paste of surveying relative density 1.10-1.25 at 60-65 ℃, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 4:
1) clinical data: chronic hepatitis 25 examples, male 19 examples, female's 6 examples, 21～55 years old age.
The present invention be take traditional Chinese medical science chronic hepatitis as example, through 25 routine clinical observations.Selecting the tcm diagnosis chronic hepatitis is standard: limb is soft weak, weak from head to foot; Poor appetite, abdominal distention, dyspepsia; Face is pitch-dark, hepatic face is arranged; Dull pain in liver; Hepatic fibrosis is serious; It is undesired that liver function transaminase continues, and other index is as defective as plasma albumin, blood total bilirubin etc.As above symptom, can make a definite diagnosis.
In making a definite diagnosis the object of observation, male 19 examples, female's 6 examples, without other serious disease, 21～55 years old age.
2) efficacy determination:
Produce effects: weak alleviation, with it energetically; Poor appetite, abdominal distention, dull pain in liver are alleviated, and hepatic region is comfortable; Hepatic face is taken on a new look to some extent, and it is pale that face becomes; The hepatic fibrosis inspection is alleviated obviously.
Effectively: weak solution, with it energetically, abdominal distention, poor appetite, hepatic face are alleviated to some extent.
Invalid: disease is unchanged.
3) Therapeutic Method: oral, each 20 milliliters of the embodiment of the present invention 1, every day 3 times, half an hour, 3 months be a course for the treatment of after meal.
4) therapeutic outcome: the patient takes the embodiment of the present invention 1 Chinese medicine oral liquid, and after 1 month, symptom has alleviation, and after taking 3 months, symptom is obviously improved.25 people of clinical experiment, produce effects 15 people wherein, effective 9 people, invalid 1 people, total effective rate 96%.
Embodiment 5:
Model case: Deng, the female, 45 years old, check and be diagnosed as chronic hepatitis patient, soft weak, the poor appetite of limb, right rib dull pain companion dry mouth with bitter taste 1 year half, laboratory examination hepatitis b surface antigen positive 2 years, take this inventive embodiments 1 Chinese medicine oral liquid, and after 1 month, symptom has alleviation, after taking 3 months, symptom is obviously improved, and checks after three courses for the treatment of that liver function is normal, and subjective symptoms disappears.
Embodiment 6:
Model case: Wang, man, 57 years old, inspection is diagnosed as chronic hepatitis patient, is not treated, rear because of diet not good enough, nausea and vomiting, yellowing of the skin, the symptom such as sclera Huang and the state of an illness is drawn attention, take this inventive embodiments 1 Chinese medicine oral liquid, after 1 month, symptom has alleviation, and after taking 3 months, symptom is obviously improved, check after three courses for the treatment of that liver function is normal, subjective symptoms disappears.
Claims (1)
1. treat the preparation method of chronic hepatitis Rhizoma Imperatae Chinese medicine oral liquid, it is characterized in that: concrete steps are as follows:
Raw material of Chinese medicine preparation by following weight portion, get 90 parts of Rhizoma Imperataes, 90 parts of Herba Artemisiae Scopariaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 30 parts of Radix Bupleuri, 90 parts of Radix Rehmanniae, 30 parts of Radix Notoginseng, 30 parts of Pheretimas, 30 parts, Radix Glycyrrhizae, water decocts secondary, 8 times of amounts that each water consumption is medical material weight, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste of surveying relative density 1.25 at 65 ℃, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
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| CN1044974C (en) * | 1994-06-17 | 1999-09-08 | 殷广全 | Anti- hepatitis B preparation |
| CN1368207A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano medicine 'Ganshule' and its preparing process |
| CN1923264B (en) * | 2006-08-02 | 2010-05-12 | 福建广生堂药业有限公司 | Capsule comprising artemisia capillaries and rhizoma imperatae for treating hepatitis |
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2012
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