CN102698195B - Radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis and preparation method - Google Patents
Radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis and preparation method Download PDFInfo
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- 208000006454 hepatitis Diseases 0.000 title claims abstract description 21
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- 238000002360 preparation method Methods 0.000 title claims description 6
- 239000003814 drug Substances 0.000 claims abstract description 22
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- 241000628997 Flos Species 0.000 claims description 11
- 239000000706 filtrate Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 235000014375 Curcuma Nutrition 0.000 claims description 9
- 241000245240 Lonicera Species 0.000 claims description 9
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
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- 239000012467 final product Substances 0.000 claims description 5
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- 244000164439 Curcuma angustifolia Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- 210000004185 liver Anatomy 0.000 abstract description 9
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- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis. The radix-curcumae traditional Chinese medicinal oral liquid is prepared by the following materials in parts by weight: 80-200 parts of radix bupleuri, 80-200 parts of schisandra chinensis, 80-200 parts of honeysuckle, 80-200 parts of radix curcumae, 80-200 parts of pittosporm and 20-60 parts of liquorice, and the effects of soothing liver, cooling blood and purging entrails and catharsis are achieved by all the medicines. The radix-curcumae traditional Chinese medicinal oral liquid disclosed by the invention has the effects of soothing liver and resolving depression, purging entrails and catharsis, treating both principal and secondary aspects of disease, strengthening the body resistance without stagnating pathogen and eliminating pathogen without damaging the body resistance, is low in cost and lasting in curative effect and is worth of being popularized and applied clinically.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of chronic hepatitis Radix Curcumae Chinese medicine oral liquid and preparation method for the treatment of.
Background technology
Chronic hepatitis mainly comprises chronic persistent hepatitis (being called for short " moving liver ") and chronic active hepatitis (being called for short " chronic active hepatitis ") two classes.Its cause of disease is mainly hepatitis B virus, and both develop by acute hepatitis, surpasses 1/2-1 as the course of disease of acute hepatitis, and symptom is lasting or liver function is still abnormal, can think to enter chronic phase.For the chronic hepatitis patient, still lack the Therapeutic Method of specially good effect at present, any medicine all never shows it to the curative effect of the definite of chronic hepatitis, is therefore still carrying out various test of cure at present.In view of etiopathogenesis may with the virulence of Strain, the factors such as the quantity of infected cell and the immune effect of patient have certain relation.In recent years, drug development very fast that is used for the treatment of clinically chronic hepatitis.Chinese medicine is used for the treatment of the medicine of viral hepatitis, and side effect is little owing to having, eutherapeutic characteristics, therefore favored by people.
Summary of the invention
The object of the present invention is to provide that a kind of side effect is little, good effect, be used for the treatment of chronic hepatitis Radix Curcumae Chinese medicine oral liquid and preparation method.
For achieving the above object, the present invention is achieved by the following technical solutions:
Treatment chronic hepatitis Radix Curcumae Chinese medicine oral liquid is to be made by the crude drug of following weight portion:
Radix Bupleuri 80-200 part, Fructus Schisandrae Chinensis 80-200 part, Flos Lonicerae 80-200 part, Radix Curcumae 80-200 part, Fructus Gardeniae 80-200 part, Radix Glycyrrhizae 20-60 part.
Described treatment chronic hepatitis Radix Curcumae Chinese medicine oral liquid is to be made by the crude drug of following weight portion:
200 parts of Radix Bupleuri, 200 parts of Fructus Schisandrae Chinensis, 200 parts of Flos Loniceraes, 200 parts of Radix Curcumaes, 200 parts of Fructus Gardeniae, 60 parts, Radix Glycyrrhizae.
The preparation method of described treatment chronic hepatitis Radix Curcumae Chinese medicine oral liquid comprises the following steps:
get 200 parts of Radix Bupleuri, 200 parts of Fructus Schisandrae Chinensis, 200 parts of Flos Loniceraes, 200 parts of Radix Curcumaes, 200 parts of Fructus Gardeniae, 60 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, and get final product.
Usage and consumption: oral, each 20 milliliters of medicine of the present invention, every day 3 times, after meal half an hour, 3 months is a course for the treatment of.This Chinese medicine oral liquid characteristics are that the patient is fully recovered is effective, and toxic and side effects is little, play the not stagnant heresy of righting, eliminating evilly hinder positive effect, and cost is low, and clinic is applied.
In the selected raw material of Chinese medicine of the present invention, Radix Bupleuri: bitter, be slightly cold, return Liver Channel, gallbladder meridian, evacuate bring down a fever, yang invigorating soothing liver-QI, cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver; Fructus Schisandrae Chinensis: sour, sweet, warm, return lung, the heart, kidney channel, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming, Flos Lonicerae: sweet, cold, attach to the lung and stomach meridians, heat-clearing and toxic substances removing, dispelling wind and heat pathogens; Radix Curcumae: hot, bitter, cool in nature; GUIXIN, liver, gallbladder meridian; Fragrance thoroughly reaches, can rise the effect that can fall, have promoting flow of QI and blood, dispersing the stagnated live-QI to relieve the stagnation of QI, removing heat from the heart to restore the consciousness, clearing away heat and cooling blood; Fructus Gardeniae: bitter, cold, GUIXIN, lung, stomach, tri-jiao channel, clearing away heat-fire, removing heat from blood, detoxifcation, dampness removing; Six internal organs are take logical as suitable, and all medicines are the merit of long memorial liver removing heat from blood, purging FU-organs diarrhea altogether.Chinese medicine oral liquid dispersing the stagnated live-QI to relieve the stagnation of QI of the present invention, purging FU-organs diarrhea, treating both the principal and secondary aspects of a disease, the not stagnant heresy of righting, eliminating evilly do not hinder positive effect, cost is low, and curative effect is lasting, and clinic is applied.
The specific embodiment
Embodiment 1:
Crude drug: 200 parts of Radix Bupleuri, 200 parts of Fructus Schisandrae Chinensis, 200 parts of Flos Loniceraes, 200 parts of Radix Curcumaes, 200 parts of Fructus Gardeniae, 60 parts, Radix Glycyrrhizae.
method for making: get 200 parts of Radix Bupleuri, 200 parts of Fructus Schisandrae Chinensis, 200 parts of Flos Loniceraes, 200 parts of Radix Curcumaes, 200 parts of Fructus Gardeniae, 60 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, and get final product.
Embodiment 2:
Crude drug: 140 parts of Radix Bupleuri, 140 parts of Fructus Schisandrae Chinensis, 140 parts of Flos Loniceraes, 140 parts of Radix Curcumaes, 140 parts of Fructus Gardeniae, Radix Glycyrrhizae 40.
method for making: get 140 parts of Radix Bupleuri, 140 parts of Fructus Schisandrae Chinensis, 140 parts of Flos Loniceraes, 140 parts of Radix Curcumaes, 140 parts of Fructus Gardeniae, Radix Glycyrrhizae 40, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, and get final product.
Embodiment 3:
Crude drug: 80 parts of Radix Bupleuri, 80 parts of Fructus Schisandrae Chinensis, 80 parts of Flos Loniceraes, 80 parts of Radix Curcumaes, 80 parts of Fructus Gardeniae, 20 parts, Radix Glycyrrhizae.
method for making: get 80 parts of Radix Bupleuri, 80 parts of Fructus Schisandrae Chinensis, 80 parts of Flos Loniceraes, 80 parts of Radix Curcumaes, 80 parts of Fructus Gardeniae, 20 parts, Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, and get final product.
Embodiment 4:
1) clinical data: chronic hepatitis 37 examples, male 17 examples, female's 20 examples, age 20-58 year.
The present invention is take traditional Chinese medical science chronic hepatitis as example, through 25 routine clinical observations.Selecting the tcm diagnosis chronic hepatitis is standard: fatigue and weak, inappetence, abdominal distention, loose stool, easily perspiration, pale tongue with thin fur, moderate pulse; Face is pitch-dark, hepatic face is arranged; Dull pain in liver; Hepatic fibrosis is serious; It is undesired that liver function transaminase continues, and other index such as plasma albumin, blood total bilirubin etc. are defective.As above symptom, can make a definite diagnosis.
In making a definite diagnosis the object of observation, male 17 examples, female's 20 examples, without other serious disease, age 20-58 year.
2) efficacy determination:
Produce effects: weak alleviation, with it energetically; Poor appetite, abdominal distention, dull pain in liver are alleviated, and the hepatic region is comfortable; Hepatic face is taken on a new look to some extent, and it is pale that face becomes; The hepatic fibrosis inspection is alleviated obviously.
Effectively: weak solution, with it energetically, abdominal distention, poor appetite, hepatic face are alleviated to some extent.
Invalid: disease is unchanged.
3) Therapeutic Method: oral, each 20 milliliters of the embodiment of the present invention 1, every day 3 times, after meal half an hour, 3 months is a course for the treatment of.
4) therapeutic outcome: the patient takes the embodiment of the present invention 1 Chinese medicine oral liquid, and after 1 month, symptom namely has alleviation, and after taking 3 months, symptom is obviously improved.37 people of clinical experiment, produce effects 15 people wherein, effective 18 people, invalid 4 people, total effective rate 89.1%.
Embodiment 5:
Model case: Cai, 32 years old, the man, suffer from that chronic hepatitis asthenia, dysphoria, uncomfortable in chest, abdominal distention, stomachache, hypochondriac pain, hyperhidrosis, bitter taste are done, epistaxis, low grade fever, take this invention after 1 month symptom alleviation is namely arranged, after taking 3 months, symptom is obviously improved, check after three courses for the treatment of that liver function is normal, subjective symptoms disappears.
Embodiment 6:
Model case: Guo, 50 years old, the female, suffer from chronic hepatitis asthenia, poor appetite, feverish sensation in the palms and soles, uncomfortable in chest, vomiting, abdominal distention, hypochondriac pain, detest oil, arthralgia, large dry stool, take this invention after 1 month symptom alleviation is namely arranged, after taking 3 months, symptom is obviously improved, and checks after three courses for the treatment of that liver function is normal, and subjective symptoms disappears.
Claims (1)
1. a preparation method for the treatment of chronic hepatitis Radix Curcumae Chinese medicine oral liquid, is characterized in that: comprise the following steps:
get 140 parts of Radix Bupleuri, 140 parts of Fructus Schisandrae Chinensis, 140 parts of Flos Loniceraes, 140 parts of Radix Curcumaes, 140 parts of Fructus Gardeniae, Radix Glycyrrhizae 40, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, and get final product.
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| CN 201210187558 CN102698195B (en) | 2012-06-07 | 2012-06-07 | Radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis and preparation method |
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| CN 201210187558 CN102698195B (en) | 2012-06-07 | 2012-06-07 | Radix-curcumae traditional Chinese medicinal oral liquid for treating chronic hepatitis and preparation method |
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| CN102698195B true CN102698195B (en) | 2013-11-06 |
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| CN1066785A (en) * | 1992-04-21 | 1992-12-09 | 沈阳中药厂 | The preparation method of Yinshanlian electuary |
| CN1078391A (en) * | 1993-01-01 | 1993-11-17 | 郑州市中药制药厂 | Qinggan Lidan oral liquid and preparation method |
| CN100571761C (en) * | 2007-08-30 | 2009-12-23 | 赵燕翼 | A kind of Chinese medicine composition and preparation method for the treatment of hepatopathy |
| CN101468185B (en) * | 2007-12-29 | 2011-04-20 | 牛海艳 | Quick-effective Chinese medicine preparation for expelling toxin of hepatitis B |
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