CN102671149B - Brucea javanica traditional Chinese medicine oral solution for curing dysentery and preparation method - Google Patents

Brucea javanica traditional Chinese medicine oral solution for curing dysentery and preparation method Download PDF

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CN102671149B
CN102671149B CN201210185561.4A CN201210185561A CN102671149B CN 102671149 B CN102671149 B CN 102671149B CN 201210185561 A CN201210185561 A CN 201210185561A CN 102671149 B CN102671149 B CN 102671149B
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dysentery
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CN102671149A (en
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黄芸
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Dong Cuilan
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract

The invention discloses a brucea javanica traditional Chinese medicine oral solution for curing dysentery. The brucea javanica traditional Chinese medicine oral solution is prepared, by weight, raw materials including brucea javanica 150-300 parts, curcuma aromatica 60-140 parts, hyacinth bean flower 150-300 parts, pseudo-ginseng 40-120 parts and small hairy euphorbia herb 60-140 parts. The brucea javanica traditional Chinese medicine oral solution has the advantages of being capable of healing diseases of patients and quick and good in effect, having small toxic and side effects, treating both principal and secondary aspects of diseases, strengthening the body resistance, causing no toxin, eliminating pathogens and being unharmful to body, enabling the diseases not to recurrent and being low in cost and worthy of clinical popularization and application.

Description

Treatment dysentery Fructus Bruceae Chinese medicine oral liquid and preparation method
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of dysentery Fructus Bruceae Chinese medicine oral liquid and preparation method for the treatment of.
Background technology
Dysentery, name of disease.See < < Prescriptions for Succouring the Sick > >.Song Yiqian has the titles such as intestinal Bleach, red white fertile, diarrhea of heat type, dysentery disease, dysentery (or " dysentery "), dysentery.< < doctor rock > > volume three: " dysentery is by due to damp and hot, or the damp and hot thing of diet, or experiences damp and hot gas; amassing in the intestines and stomach, be just evil resistance, and the operation of taste is not normal; so diet is stagnated day by day, turn to and lose turbidly, among gluing the intestines and stomach; the machine of operation, benefit is with unfavorable, and the stagnation of QI be fire; be mixed into heresy with suffered damp and hot gas; attack thorn and have a pain " has bellyache and diarrhea inferior frequent, and diarrhea is red to be glued and freeze in vain, the diseases such as tenesmus.More explicitly point out dysentery later age many by unhygienic diet, experience the gas of epidemic disease poison, intestinal is produced stagnant, conduct not normal due to, when distinguishing that its deficiency and excess minute another matter controls.And red white sticky the freezing of dysentery institute purgation, < < medicine principle dysentery door > > meaning: " its red person's blood system is injured, belongs to small intestinal; White person's edema caused by disorder of QI is injured, belongs to large intestine." the bright doctor's fingers and palms of < < > >: " damp and hot long-pending, do in blood system redly, do in edema caused by disorder of QI white "; clinically, excess syndrome should clearing away heat and eliminating dampness, removing pathogenic heat from blood and toxic substance from the body; consumer product dredge stasis is method; evilly contain weakened body resistance person, should eliminating pathogenic factor for supporting vital QI, and dual-purpose promoting the circulation of blood regulating QI; " promoting the circulation of blood is just pus spontaneous recovery for this what is called, regulating QI is heavy from removing afterwards ", deficiency syndrome are worked as invigorating the spleen and replenishing QI, and warming YANG is astringent or styptic treatment for spontaneous sweating.Dysentery can be divided into again multiple, by the different causes of disease, disease (color that comprises disease feelings weight and the course of disease and dysentery), roughly there are summer dysentery, dysentery due to damp-heat, dysentery due to pathogenic, fulminant dysentery, diarrhea due to disorder of qi, fulminant dysentery, hematodiarrhoea, cold dysentery, fasting dysentery, chronic dysentery, chronic dysentery with frequent relapse, fulminant dysentery, bloody dysentery, Hakuri, dysentery with red and white feces, dysentery with multicolored stool etc. multiple, the dysentery that the traditional Chinese medical science is said, both the dysentery that had been equal to modern medicine, also comprises the disease of amebic dysentery, ulcerative colitis, allergic colitis and some other intestinal infection, the intestinal development of evil in febrile disease causing such as poisoning, absorption function imbalance.Chinese medicine is used for the treatment of the medicine of dysentery, owing to having little, the eutherapeutic feature of side effect, therefore favored by people.
Summary of the invention
The object of the present invention is to provide that a kind of side effect is little, good effect, be used for the treatment of dysentery Fructus Bruceae Chinese medicine oral liquid and preparation method.
For achieving the above object, the present invention is achieved by the following technical solutions:
Treatment dysentery Fructus Bruceae Chinese medicine oral liquid, is characterized in that: be to be made by the crude drug of following parts by weight:
Fructus Bruceae 150-300 part, Radix Curcumae 60-140 part, Flos dolichoris 150-300 part, Radix Notoginseng 40-120 part, Herba Euphorbiae Thymifoliae 60-140 part.
Described treatment dysentery Fructus Bruceae Chinese medicine oral liquid is to be made by the crude drug of following parts by weight:
300 parts of Fructus Bruceaes, 140 parts of Radix Curcumaes, 300 parts of Flos dolichoris, 120 parts of Radix Notoginseng, 140 parts of Herba Euphorbiae Thymifoliaes.
Described treatment dysentery Fructus Bruceae Chinese medicine oral liquid and preparation method, comprise the following steps:
A, Fructus Bruceae are ground into coarse powder, get 300 parts of Fructus Bruceaes, 140 parts of Radix Curcumaes, 140 parts of waters decoction secondaries of Herba Euphorbiae Thymifoliae, and each water consumption is 10 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 120 parts of 300 parts of Flos dolichoris, Radix Notoginseng and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
How instructions of taking: every day 3 times, a dose is 10ml, a month course for the treatment of, took effect at 1-5 days after taking medicine, and cure 1 interior course for the treatment of.This Chinese medicine oral liquid feature is to make patient fully recover, instant effect, and effective, toxic and side effects is little, plays the not stagnant heresy for the treatment of both the principal and secondary aspects of a disease, righting, does not eliminating evilly hinder positive effect, and without recurrence, cost is low, and clinic is applied.
In the selected raw material of Chinese medicine of the present invention, Radix Notoginseng: sweet, micro-hardship, temperature, GUIXIN, liver, spleen channel, removing stasis to stop bleeding, reducing swelling and alleviating pain; Herba Euphorbiae Thymifoliae: sour, puckery, cool, heat clearing away, dampness removing, detumescence, removing toxic substances, treating malaria disease, dysentery, has loose bowels; Acute mastitis, hemorrhoid.Fructus Bruceae: bitter, cold, return large intestine, Liver Channel, heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria, dysentery relieving; Radix Curcumae: pungent, bitter, cold, GUIXIN, liver, gallbladder meridian, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clearing away heat and cooling blood, removing heat from the heart to restore the consciousness, dampness removing jaundice eliminating; Flos dolichoris: flat, sweet light, nontoxic, spleen, stomach, large intestine channel, expelling summer-heat and damp and middle spleen invigorating, main summer Sunstroke wets, generates heat, has loose bowels, dysentery; All medicines are played the merit of QI and blood regulating, heat-clearing and toxic substances removing altogether, oral liquid of the present invention can be removed rapidly the symptoms such as smelly dirty, the burning sensation of the anus of stool being yellowish-brown, abnormal smells from the patient due to dysentery damp-heat diarrhea type, dysphoria with smothery sensation are thirsty, oliguria with yellow urine dry pharynx, slight pharyngalgia, specially medicine is specially controlled, evident in efficacy.Points for attention: anemia of pregnant woman's forbidding.
The specific embodiment
Embodiment 1:
Crude drug: 300 parts of Fructus Bruceaes, 140 parts of Radix Curcumaes, 300 parts of Flos dolichoris, 120 parts of Radix Notoginseng, 140 parts of Herba Euphorbiae Thymifoliaes.
Method for making: A, Fructus Bruceae are ground into coarse powder, get 300 parts of Fructus Bruceaes, 140 parts of Radix Curcumaes, 140 parts of waters decoction secondaries of Herba Euphorbiae Thymifoliae, and each water consumption is 10 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 120 parts of 300 parts of Flos dolichoris, Radix Notoginseng and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
Embodiment 2:
Crude drug: 225 parts of Fructus Bruceaes, 100 parts of Radix Curcumaes, 225 parts of Flos dolichoris, 80 parts of Radix Notoginseng, 100 parts of Herba Euphorbiae Thymifoliaes.
Method for making: A, Fructus Bruceae are ground into coarse powder, get 225 parts of Fructus Bruceaes, 100 parts of Radix Curcumaes, 100 parts of waters decoction secondaries of Herba Euphorbiae Thymifoliae, and each water consumption is 10 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 80 parts of 225 parts of Flos dolichoris, Radix Notoginseng and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
Embodiment 3:
Crude drug: 150 parts of Fructus Bruceaes, 60 parts of Radix Curcumaes, 150 parts of Flos dolichoris, 40 parts of Radix Notoginseng, 60 parts of Herba Euphorbiae Thymifoliaes.
Method for making: A, Fructus Bruceae are ground into coarse powder, get 150 parts of Fructus Bruceaes, 60 parts of Radix Curcumaes, 60 parts of waters decoction secondaries of Herba Euphorbiae Thymifoliae, and each water consumption is 10 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 40 parts of 150 parts of Flos dolichoris, Radix Notoginseng and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
Embodiment 4:
Clinical trial
(1) subjects: one data: adopt Chinese medicine composition of the present invention to treat altogether 50 routine patients, male 20 examples wherein, female's 30 examples, the oldest person 75 years old, age reckling 17 years old.
(2) Therapeutic Method: every day 3 times, a dose is 10ml one month is a course for the treatment of.
(3) treatment standard
Cure: sign is improved completely, lets out dysentery and stops, and diet is normal, in high spirits.
Effective: sign is significantly improved, to let out dysentery and substantially stop, diet is normal, in high spirits.
Effective: sign is improved, letting out dysentery has minimizing, and diet improves, and spirit is improved.
Invalid: sign is without change, and symptom is as front.
(4) therapeutic outcome: patient's 50 examples, through treatment in 1 month, wherein cure 30 examples, effective 15 examples, effective 5 examples, invalid 0 example, total effective rate reaches 100%.
Embodiment 5:
Model case: health, man, 75 years old, main suit: often suffer from diarrhoea, borborygmus, loose stool, take the embodiment of the present invention 1 Chinese medicine oral liquid, abdominal distention on the 2nd only, slightly alleviate by diarrhoea, symptom obviously alleviates, following the service 7 days, the gradually molding of defecating, symptom is greatly taken on a new look, following the service 7 days, and patient has rosy cheeks, symptom all disappears, recovery from illness.
Embodiment 6:
Model case: the summer, female, 45 years old, abdominal part distension pain, loose stool and diarrhea day 4-6 time, diet is dull, takes the embodiment of the present invention 1 Chinese medicine oral liquid, and symptom obviously alleviated on 3rd, following the service 5 days, the gradually molding of defecating, symptom is greatly taken on a new look, following the service 10 days, patient's recovery from illness.

Claims (1)

1. a preparation method for the treatment of the Fructus Bruceae Chinese medicine oral liquid of dysentery, is characterized in that: comprise the following steps:
A, Fructus Bruceae are ground into coarse powder, get 225 parts of Fructus Bruceaes, 100 parts of Radix Curcumaes, 100 parts of waters decoction secondaries of Herba Euphorbiae Thymifoliae, and each water consumption is 10 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 80 parts of 225 parts of Flos dolichoris, Radix Notoginseng and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
CN201210185561.4A 2012-06-06 2012-06-06 Brucea javanica traditional Chinese medicine oral solution for curing dysentery and preparation method Expired - Fee Related CN102671149B (en)

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