CN102670922B - Traditional Chinese medicine oral fluid with seeds of feather cockscomb for treating diarrhea and preparing method thereof - Google Patents

Abstract

The invention discloses a Chinese medicine oral fluid with seeds of feather cockscomb for treating diarrhea. The Chinese medicine oral fluid with seeds of feather cockscomb for treating diarrhea is prepared by the following components in part by weight: 150 to 300 parts of seed of feather cockscomb, 60 to 120 parts of pseudo-ginseng, 80 to 140 parts of Chinese yam, 80 to 140 parts of thymifolious euphorbia herb and 150 to 300 parts of purslane. The Chinese medicine oral fluid has the characteristics that patients can be healed, the effect is rapid and good, the toxic and side effects are small, the effects of treating both principal and secondary aspects of disease, strengthening the healthy energy not to lag the pathogenic factor, and eliminating the pathogenic factor not to injury the healthy energy are served, no recurrence phenomenon exits, and the cost is low, thereby being worthy of clinical popularization and application.

Description

Treatment dysentery Semen Celosiae Chinese medicine oral liquid and preparation method

Technical field

The invention belongs to the field of Chinese medicines, particularly one is treated dysentery Semen Celosiae Chinese medicine oral liquid and preparation method.

Background technology

Dysentery is to suffer from abdominal pain, tenesmus, the disease that the red white pus and blood of diarrhea is primary symptom.Primary disease all can be fallen ill all the year round, but is more common in summer and autumn.The dysentery of Chinese medicine category not only comprises modern medicine antibacterial or amebic dysentery, also including the various diseases such as acute chronic enteritis, ulcerative colitis.The many gas damp and hot by being subject to outward, that epidemic disease is malicious of primary disease, internal injury diet raw food, impairing the spleen and stomach and intestinal internal organs form.Dysentery is the common transmittable disease of summer and autumn, if treatment not in time can concurrent septicemia, malnutrition, anemia, leukemoid reaction can appear in protracted course of disease; And there are some researches show, bone-loss is very general in inflammatory bowel, easily there is multiple location fracture.Therefore, the sick active treatment of sending out early stage is very important for the generation of intervening disease progression, blocking-up adverse events.Chinese medicine is used for the treatment of the medicine of dysentery, owing to having little, the eutherapeutic feature of side effect, therefore favored by people.

Summary of the invention

The object of the present invention is to provide that a kind of side effect is little, good effect, be used for the treatment of dysentery Semen Celosiae Chinese medicine oral liquid and preparation method.

For achieving the above object, the present invention is achieved by the following technical solutions:

Treatment dysentery Semen Celosiae Chinese medicine oral liquid is to be made up of the crude drug of following parts by weight:

Semen Celosiae 150-300 part, Radix Notoginseng 60-120 part, Rhizoma Dioscoreae 80-140 part, Herba Euphorbiae Thymifoliae 80-140 part, Herba Portulacae 150-300 part.

Described treatment dysentery Semen Celosiae Chinese medicine oral liquid is to be made up of the crude drug of following parts by weight:

300 parts of Semen Celosiae, 120 parts of Radix Notoginseng, 140 parts of Rhizoma Dioscoreaes, 140 parts of Herba Euphorbiae Thymifoliaes, 300 parts of Herba Portulacaes.

Described treatment dysentery Semen Celosiae Chinese medicine oral liquid and preparation method, comprise the following steps:

A, Semen Celosiae are ground into coarse powder, get 300 parts of Semen Celosiae, 140 parts of Herba Euphorbiae Thymifoliaes, 300 parts of Herba Portulacaes, and water decocts secondary, each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;

B, get 140 parts of 120 parts of Radix Notoginseng, Rhizoma Dioscoreae and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, and leaves standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;

C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, to obtain final product.

How instructions of taking: every day 3 times, a dose is 10ml, a month course for the treatment of, took effect at 1 day after taking medicine, and cure 1 interior course for the treatment of.This Chinese medicine oral liquid feature is to make patient fully recover, instant effect, and effective, toxic and side effects is little, plays the not stagnant heresy for the treatment of both the principal and secondary aspects of a disease, righting, does not eliminating evilly hinder positive effect, and without recurrence, cost is low, and clinic is applied.

Semen Celosiae in the selected raw material of Chinese medicine of the present invention: be slightly cold, hardship, return Liver Channel, liver heat removing, improving eyesight, nebula removing, herb clearing away heat-damp and promoting diuresis; Radix Notoginseng: sweet, micro-hardship, temperature, GUIXIN, liver, spleen channel, removing stasis to stop bleeding, reducing swelling and alleviating pain; Rhizoma Dioscoreae: sweet, flat, return spleen, lung, kidney channel, supplementing QI and nourishing YIN, benefit strengthening spleen and lung, tonifying the kidney to consolidate the essence; Herba Euphorbiae Thymifoliae: sour, puckery, cool, heat clearing away, dampness removing, detumescence, removing toxic substances, treating malaria disease, dysentery, has loose bowels; Herba Portulacae: cold, sour, return liver, large intestine channel, heat-clearing and toxic substances removing, cooling blood for hemostasis; All medicines are played the merit of clearing away heat,cooling blood and removing toxin altogether, and oral liquid of the present invention can be removed rapidly the symptom of high heat due to fulminant dysentery type, tic, cold extremities, profuse sweating, and specially medicine is specially controlled, evident in efficacy.Points for attention: anemia of pregnant woman's forbidding.

The specific embodiment

Embodiment 1:

Crude drug: 300 parts of Semen Celosiae, 120 parts of Radix Notoginseng, 140 parts of Rhizoma Dioscoreaes, 140 parts of Herba Euphorbiae Thymifoliaes, 300 parts of Herba Portulacaes.

Method for making: A, Semen Celosiae are ground into coarse powder, get 300 parts of Semen Celosiae, 140 parts of Herba Euphorbiae Thymifoliaes, 300 parts of Herba Portulacaes, and water decocts secondary, each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;

B, get 140 parts of 120 parts of Radix Notoginseng, Rhizoma Dioscoreae and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, and leaves standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;

C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, to obtain final product.

Embodiment 2:

Crude drug: 225 parts of Semen Celosiae, 90 parts of Radix Notoginseng, 110 parts of Rhizoma Dioscoreaes, 110 parts of Herba Euphorbiae Thymifoliaes, 225 parts of Herba Portulacaes.

Method for making: A, Semen Celosiae are ground into coarse powder, get 225 parts of Semen Celosiae, 110 parts of Herba Euphorbiae Thymifoliaes, 225 parts of Herba Portulacaes, and water decocts secondary, each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;

B, get 110 parts of 90 parts of Semen Celosiae Radix Notoginseng, Rhizoma Dioscoreae and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, and leaves standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;

C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, to obtain final product.

Embodiment 3:

Crude drug: 150 parts of Semen Celosiae, 60 parts of Radix Notoginseng, 80 parts of Rhizoma Dioscoreaes, 80 parts of Herba Euphorbiae Thymifoliaes, 150 parts of Herba Portulacaes.

Method for making: A, Semen Celosiae are ground into coarse powder, get 150 parts of Semen Celosiae, 80 parts of Herba Euphorbiae Thymifoliaes, 150 parts of Herba Portulacaes, and water decocts secondary, each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;

B, get 80 parts of 60 parts of Radix Notoginseng, Rhizoma Dioscoreae and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, decoct secondary, each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, and leaves standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;

C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, to obtain final product.

Embodiment 4:

Clinical trial

(1) subjects: one data: adopt Chinese medicine composition of the present invention to treat altogether 40 routine patients, wherein male 21 examples, female's 19 examples, the oldest person 70 years old, age reckling 14 years old.

(2) Therapeutic Method: every day 3 times, a dose is 10ml one month is a course for the treatment of.

(3) treatment standard

Cure: sign is improved completely, lets out dysentery and stops, and diet is normal, in high spirits.

Effective: sign is significantly improved, to let out dysentery and substantially stop, diet is normal, in high spirits.

Effective: sign is improved, letting out dysentery has minimizing, and diet improves, and spirit is improved.

Invalid: sign is without change, and symptom is as front.

(4) therapeutic outcome: patient's 40 examples, through treatment in 1 month, wherein cure 30 examples, effective 5 examples, effective 5 examples, invalid 0 example, total effective rate reaches 100%.

Embodiment 5:

Model case: Gong, man, 62 years old, main suit's hyperpyrexia, stupor, passing stool with blood and pus 1 day, fever after conscious suffering from cold, 41.2 ℃ of body temperature, companion's aversion to cold, feel sick, tell that yellow fluid, mind are gone into a coma gradually, diarrhoea then, are bloody purulent stool, tens of times of day, take the present invention, embodiment 1 Chinese medicine oral liquid, abdominal distention on the 2nd is only, diarrhoea is slightly alleviated, and symptom obviously alleviates, following the service 7 days, the gradually molding of defecating, symptom is greatly taken on a new look, and diet takes a turn for the better, and spirit is gradually shaken, following the service 5 days, patient has rosy cheeks, and symptom all disappears, recovery from illness.

Embodiment 6:

Model case: Qiu, female, 35 years old, main suit's hyperpyrexia, passing stool with blood and pus 1 day, fever after conscious suffering from cold, 40 ℃ of body temperature, companion aversion to cold, feel sick, tell yellow fluid, diarrhoea bloody purulent stool, number of days five ~ eight times, takes the embodiment of the present invention 1 Chinese medicine oral liquid, symptom obviously alleviated on 2nd, following the service 5 days, the gradually molding of defecating, diet takes a turn for the better, following the service 8 days, patient's recovery from illness.

Claims (1)

1. a preparation method for the treatment of dysentery Semen Celosiae Chinese medicine oral liquid, is characterized in that: comprise the following steps:

A, Semen Celosiae are ground into coarse powder, get 225 parts of Semen Celosiae, 110 parts of Herba Euphorbiae Thymifoliaes, 225 parts of Herba Portulacaes, and water decocts secondary, each water consumption is 10 times of amounts of medical material weight, and each 1-2 hour, filters, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, and leaves standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;

B, get 110 parts of 90 parts of Radix Notoginseng, Rhizoma Dioscoreae and be ground into 20 order fine powders, water decocts secondary, and each water consumption is 5 times of amounts of medical material weight, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;

C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, to obtain final product.