CN103223046B - Traditional Chinese medicine for treating hyperplasia of mammary glands - Google Patents
Traditional Chinese medicine for treating hyperplasia of mammary glands Download PDFInfo
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- CN103223046B CN103223046B CN201310161952.7A CN201310161952A CN103223046B CN 103223046 B CN103223046 B CN 103223046B CN 201310161952 A CN201310161952 A CN 201310161952A CN 103223046 B CN103223046 B CN 103223046B
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Abstract
The invention relates to the technical field of traditional Chinese medicines. A traditional Chinese medicine for treating hyperplasia of mammary glands is characterized in that the medicine is prepared from the following raw drugs: by weight, 10g of radix paeoniae rubrathe, 15g of radix bupleuri, 10g of frankincense, 15g of semen citri reticulatae, 10g of Chinese angelica, 15g of the seed of cowherb, 5g of Poria cocos, 10g of bitter orange, 20g of red sage root, 5g of green tangerine peel, 10g of Sinapis alba, 15g of honeycomb and 20g of barbat skullcap. Through dialectical compatibility, components of the traditional Chinese medicine provided by the invention are complementary in functions, have synergistic effects, and have efficacy of soothing the liver and resolving depression, reducing phlegm and removing stasis, softening hardness and dissipating binds, invigorate blood circulation and relieving pain and the like. By the adoption of the traditional Chinese medicine, immunity of the organism can be raised, endocrine function is balanced, and hyperplastic tissues are eliminated so as to reach the purpose of treating hyperplasia of mammary glands.
Description
Technical field
The present invention relates to a kind of field of Chinese herbal medicine technology, specifically a kind of Chinese medicine for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is mainly the hyperplasia of prostate of mammary gland interstitial, and hypertrophy can betide glandular tube and around and with the cyst differing in size form; Also can occur in glandular tube and show as the nipple sample hypertrophy of epithelium, the cystic dilatation of companion's latex dust.In addition still there is, a kind of type of lobule essence hypertrophy.The pathogenic factor of cyclomastopathy and pathogeny are relevant with endocrine disturbance and Nervous and Mental Factors, the neural Nervous and Mental Factors that external environment condition, work and the living condition of people living, inter personal contact, various pressure cause etc. all can make the interior environment of human body change, thereby affect the function of hormonal system, and then the secretion that makes a certain or several hormones occurs abnormal, lutein secretion reduces, it is the major reason of cyclomastopathy morbidity that estrogen increases relatively, causes cyclomastopathy.Existing Therapeutic Method and medicine are varied, but do not reach yet gratifying effect, as: treatment at present can only make the tissue of hypertrophy dwindle, but can not disappear completely, and cyclomastopathy also can recur, and can not effect a radical cure completely.
Summary of the invention
The present invention is directed to prior art deficiency, provide a kind of cost low, treatment cyclomastopathy curative effect is high, and can prevent allergy, has the blood circulation of breast of improvement, and blood vessel dilating increases latex dust elasticity, makes that breast tissue blood flow is unimpeded, eliminate pain; Adjusting immunity simultaneously, neural, endocrine function, make ovarian function normalization, thereby make lutein and oestrogen balance secretion, solves the effects such as cyclomastopathy basic reason, and the cyclomastopathy that a variety of causes is caused is effective medicine all.
The present invention solves the problems of the technologies described above adopted technical scheme: a kind of Chinese medicine for the treatment of cyclomastopathy, is characterized in that it is to be made up of the material medicine of following weight: Radix Paeoniae Rubra 10g, Radix Bupleuri 15g, Olibanum 10g, Semen Citri Reticulatae 15g, Radix Angelicae Sinensis 10g, Semen Vaccariae 15g, Poria 5g, Fructus Aurantii Immaturus 10g, Radix Salviae Miltiorrhizae 20g, Pericarpium Citri Reticulatae Viride 5g, Semen Sinapis Albae 10g, Nidus Vespae 15g, Herba Scutellariae Barbatae 20g.
In medicament of the present invention, Radix Paeoniae Rubra hardship, is slightly cold, and returns Liver Channel.Clots absorbing, pain relieving, removing heat from blood, detumescence.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.Radix Bupleuri nature and flavor are bitter flat, enter liver, gallbladder meridian.Function for delivering, bring down a fever, soothing the liver, resolving depression, yang invigorating.Cure mainly side of body distending pain, menoxenia.Modern pharmacological research proves: Radix Bupleuri has calmness, analgesia, has the distending pain uncomfortable in chest of releasing, dissipating depression of QI regulating menoxenia; And have Promote immunity function, phagocytic function strengthens, Natural killer activity strengthens.Improve special viral antibody titre, improve lymphocyte and turn core rate.Improve skin delayed hypersensitivity reaction.Olibanum can deep layer be removed the morbid substance such as acinus of breast, body of gland, glandular sac, eliminates lump.The 'beta ' activity factor that it is rich in simultaneously has the effect of progestogen, can reduce peripheral blood estradiol level, the reproduction speed of galactophore epithelial cell DNA slows down, suppress its mitosis, reduce its growth, differentiation, division and hypertrophy activity, the cell of hypertrophy is transformed to normal cell, thereby reach the object of prevention and treatment cyclomastopathy.Semen Citri Reticulatae enters Liver and kidney warp, cures mainly acute mastitis, mastitis.Radix Angelicae Sinensis sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, in row, has benefit, is the key medicine in blood.Thereby it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example, through women's such as (when menstrual onsets, occur mouth and nose bleed) commonly encountered diseases, can be used angelica for treating.Radix Angelicae Sinensis and extract sodium ferulate thereof and Radix Angelicae Sinensis polysaccharide have obvious stimulation to monocytes/macrophages system, and the body of immunologic hypofunction is also had to immune regulation and restitution.Radix Angelicae Sinensis also has facilitation to the lymphocyte transformation of Healthy People.Semen Vaccariae bitter in the mouth, property is flat; Return liver, stomach warp; Enter blood system, directly and not keep; There is promoting blood circulation to restore menstrual flow, stimulating milk secretion eliminating carbuncle, inducing diuresis for treating stranguria syndrome; Cure mainly dysmenorrhea due to blood stasis, amenorrhea, galactostasis, acute mastitis skin ulcer is swollen, stranguria, dysuria.The immunologic function of pachyman physical ability enhancing body.The pungent row hardship of Fructus Aurantii Immaturus is fallen, and kind dispelling the stagnated QI is except painful abdominal mass, consumer product dredge stasis, stagnation of QI pain in chest and hypochondrium.The capable stagnant and pain relieving of the kind dispelling the stagnated QI of this product, the pain in chest and hypochondrium for the treatment of QI and blood retardance.Radix Salviae Miltiorrhizae has the reparation and the regeneration that promote tissue, and red sage formulation is removed fast to necrotic myocardium; Fibroblast differentiation, collagen fiber form more obvious; Granulation forms comparative maturity.Local congestion alleviates, blood circulation improves, and healing time shortens.Fibroblast to hyperplasia has inhibitory action.Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant.Control breast side of body gastralgia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction piece.Semen Sinapis Albae is pungent, heat; Warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.Cure mainly and reduce phlegm by drink; Mass dissipating and swelling eliminating.Nidus Vespae master is containing compositions such as Cera Flava resin and one " Nidus Vespae oil ", protein, calcium, ferrum, have antiinflammatory, antibacterial, ease pain, the effect such as reduction body temperature, clinical practice is in acute mastitis, pyogenic infection etc.; Herba Scutellariae Barbatae acrid in the mouth; Bitter; Cold in nature.Return lung meridian; Liver Channel; Kidney channel.Heat-clearing and toxic substances removing; Dissipating blood stasis hemostasis; Inducing diuresis to remove edema.Pyretic toxicity carbuncle; Have sore throat; Lung abscess; Intestinal carbuncle; Scrofula; Venom; Traumatic injury; Spit blood; Epistaxis; Stranguria with blood; Edema; Ascites and cancer.The component of Chinese medicine of the present invention is through dialectical compatibility, complement each other using, there is synergism, reach the effects such as dispersing the stagnated live-QI to relieve the stagnation of QI, dissipating phlegm and removing blood stasis, hard masses softening and resolving, promoting blood circulation and stopping pain, can improve immunity of organisms, balance endocrine function, disappears the tissue of hypertrophy, thereby reaches the object for the treatment of cyclomastopathy.
Detailed description of the invention:
Embodiment 1: a kind of Chinese medicine for the treatment of cyclomastopathy, it is to be made up of the material medicine of following weight: Radix Paeoniae Rubra 10g, Radix Bupleuri 15g, Olibanum 10g, Semen Citri Reticulatae 15g, Radix Angelicae Sinensis 10g, Semen Vaccariae 15g, Poria 5g, Fructus Aurantii Immaturus 10g, Radix Salviae Miltiorrhizae 20g, Pericarpium Citri Reticulatae Viride 5g, Semen Sinapis Albae 10g, Nidus Vespae 15g, Herba Scutellariae Barbatae 20g.Get above-mentioned 13 taste Chinese herbal medicine add water 1000 grams with slow fire endure out frying yellowly from fire, the filter of removing slag is clean, treat slightly cold after, the cool filtration of drying in the air, get filtrate autoclave sterilization, make treatment cyclomastopathy Chinese medicine decoction, every day potion, decocting takes at twice, within premenstrual 7 days, start to take medicine at every turn, withdraw menstrual period, through after continue clothes, and keep happy.1 dose of every day, decocting is decoction being taken warmly at twice, and serveing on 20 days was 1 course for the treatment of.
A kind of Clinical Action of Traditional Chinese Drugs for the treatment of cyclomastopathy is summed up:
One, case selection: selected case is the cyclomastopathy that a variety of causes causes, totally 211 routine cyclomastopathy patients, are clinic case; Case selection standard: 1, have typical clinical manifestation, have one-sided or bilateral lump in breast, conscious pain or tenderness are obvious.2, all cases all have the shooting of mammary gland B ultrasonic or x-ray mammary gland to diagnose for auxiliary examination, and get rid of breast carcinoma, the mastopathy such as mammary gland fibroma, all cases are divided into treatment group of the present invention (treatment group is totally 126 examples) and Western medicine Tabellae Asparagini group (matched group is totally 85 examples) at random, two groups of case-datas are learned by statistics and are processed there was no significant difference (P > 0.05), have comparability.
Two, diagnostic criteria: diagnostic criteria is with reference to the diagnostic criteria of newly organized " surgery ".
Three, Therapeutic Method: every day potion, decocting takes at twice, within premenstrual 7 days, starts to take medicine at every turn, withdraw menstrual period, through after continue clothes, and keep happy.
Four, curative effect judgement: according to breast disease special commission of surgery branch of Chinese association of traditional Chinese medicine standard.
Recovery from illness: lump disappears, mastalgia disappears, drug withdrawal nothing recurrence in 3 months;
Effective: lump in breast maximum gauge dwindles more than 1/2, and mastalgia alleviates;
Invalid: lump in breast is without dwindling, and mastalgia takes a turn for the better but has recurrence.
Five, therapeutic effect: use the present invention to treat 126 routine cyclomastopathy patients, carry out treatment effectiveness evaluation according to the standard of curative effect evaluation, cure 64 examples, account for 50.79%, effective 38 examples, account for 30.16%, effective 18 examples, account for 14.29%, invalid 6 examples, account for 4.76%, total effective 120 examples, account for 95.24%.Chinese medicine of the present invention is treatment group (totally 126 examples), and Western medicine Tabellae Asparagini is matched group (totally 85 examples), matched group: Tabellae Asparagini, each 1, every day three times.More than treatment, all taking 3 months as 1 course for the treatment of, is added up curative effect after 1 course for the treatment of of taking medicine.12 examples of fully recovering (14.12%), effective 16 examples (18.82%), effective 25 examples (29.41%), invalid 32 examples (37.65%), total effective 53 examples (62.35%).Two groups of therapeutic outcomes are relatively in table 1.
Table 1 liang group curative effect comparison [example (%)]
Between group, compare: * X
2=29.63, P < 0.001; △ x
2=37.17, P < 0.01
Learn and process by statistics, Chinese drug-treated group effect of the present invention is remarkable, is obviously better than Western medicine Tabellae Asparagini group (P < 0.01).The results are shown in subordinate list.
Result shows: Chinese medicine decoction oral administration of the present invention acts on mammary gland tissue, improves blood circulation of breast, and blood vessel dilating increases latex dust elasticity.Make that breast tissue blood flow is unimpeded, eliminate pain simultaneously; The compositions such as contained Olibanum can deep layer be removed the morbid substance such as acinus of breast, body of gland, glandular sac, eliminate lump.The 'beta ' activity factor that it is rich in simultaneously has the effect of progestogen; can reduce peripheral blood estradiol level; the reproduction speed of galactophore epithelial cell DNA slows down; suppress its mitosis; reduce its growth, differentiation, division and hypertrophy activity; the cell of hypertrophy is transformed to normal cell; further regulate hypothalamic-pituitary-ovarian function; regulate immunity, neural, endocrine function; make ovarian function normalization; thereby make lutein and oestrogen balance secretion, solve cyclomastopathy root problem, thereby reach the object of prevention and treatment cyclomastopathy.
Six, model case
Patient 1, and female 36 years old, marriedly educates.In first visit on October 5 in 2010.Bilateral mastalgia 3 years, pain more so before passing through and after angry.The two newborn outside upper quadrants of palpation all can touch flat lump, the about 2.5cmx2.5cm in right side, the about 3.1cmx3.1cm in left side, matter is tough, smooth, movable, tenderness is obvious, be diagnosed as cyclomastopathy through ultrasound diagnosis, with decoction treatment of the present invention 3 months, mammary gland pain and lump disappeared completely, with examining half a year without recurrence.
Patient 2, and female 43 years old, marriedly educates.In first visit on February 20 in 2012.Bilateral mastalgia 5 years, increases the weight of 2 years, and before passing through, pain more so.The outside upper quadrant of the right breast of palpation, the outside upper quadrant of left breast and UIQ all can touch flat lump, the about 1.9cmx2.4cm in right side, the about 3.5cmx3.8cm in left side, matter is tough, smooth, movable, tenderness is obvious, is diagnosed as cyclomastopathy through ultrasound diagnosis, with decoction treatment of the present invention, within premenstrual 7 days, start to take medicine at every turn, withdraw menstrual period, through after continue clothes, and keep happy.After 2 months, mammary gland pain and lump disappear completely, with examining 1 year without recurrence.
Patient 3, and female 40 years old, marriedly educates.In JIUYUE in 2011 first visit on the 12nd.Bilateral mastalgia 2 years, pain increases the weight of before passing through and after angry.The outside upper quadrant of the right breast of palpation and UIQ, the outside upper quadrant of left breast all can touch flat lump, matter is tough, smooth, movable, tenderness is obvious, check the about 2.7cmx3.6cm in right side through breast molybdenum target x-ray, left side about 2.1cmx2.8cm size hypertrophy, be diagnosed as cyclomastopathy, with decoction treatment of the present invention 3 months, mammary gland pain and lump disappeared completely, with examining half a year without recurrence.
Claims (1)
1. treat a Chinese medicine for cyclomastopathy, it is characterized in that it is to be made up of the material medicine of following weight: Radix Paeoniae Rubra 10g, Radix Bupleuri 15g, Olibanum 10g, Semen Citri Reticulatae 15g, Radix Angelicae Sinensis 10g, Semen Vaccariae 15g, Poria 5g, Fructus Aurantii Immaturus 10g, Radix Salviae Miltiorrhizae 20g, Pericarpium Citri Reticulatae Viride 5g, Semen Sinapis Albae 10g, Nidus Vespae 15g, Herba Scutellariae Barbatae 20g; Get above-mentioned 13 taste Chinese herbal medicine and add water 1000 grams and endure out frying yellowly from fire with slow fire, the filter of removing slag is clean, treat slightly cold after, the cool filtration of drying in the air, gets filtrate autoclave sterilization, makes the Chinese medicine decoction for the treatment of cyclomastopathy.
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| CN103948747A (en) * | 2014-05-21 | 2014-07-30 | 刘黎明 | Traditional Chinese medicinal preparation for treating liver-qi stagnation type breast distending pain |
| CN110464798A (en) * | 2018-05-09 | 2019-11-19 | 上海牛樟芝生物技术有限公司 | Activation detumescence Chinese medicine repairs breast patch and preparation method thereof |
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| CN100418546C (en) * | 2004-03-05 | 2008-09-17 | 张健 | Skin penetration and adsorption medicine for treating proliferation of mammary gland |
| CN1857550A (en) * | 2006-03-20 | 2006-11-08 | 南京同仁堂药业有限责任公司 | Medicine composition for treating lobular hyperplasia of mammary gland and its preparing method |
| WO2009062338A1 (en) * | 2007-11-14 | 2009-05-22 | Shangxian Gao | A lactogenic chinese medicine for treatment and prevention of gynecopathy, methods of preparation and uses thereof |
| CN101642519B (en) * | 2009-08-22 | 2011-02-16 | 甘肃省医学科学研究院 | Chinese patent medicine for treating mammary gland hyperplasia and preparation technique thereof |
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