CN105194588A - Traditional Chinese medicine preparation for treating liver cirrhosis - Google Patents

Traditional Chinese medicine preparation for treating liver cirrhosis Download PDF

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CN105194588A
CN105194588A CN201510765756.XA CN201510765756A CN105194588A CN 105194588 A CN105194588 A CN 105194588A CN 201510765756 A CN201510765756 A CN 201510765756A CN 105194588 A CN105194588 A CN 105194588A
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chinese medicine
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王国宝
孙玉东
王勇
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王国宝
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating liver cirrhosis. The traditional Chinese medicine preparation is prepared from the following raw materials: radix bupleuri, white peony root, liquorice, fructus aurantii, pericarpium citri reticulatae, rhizoma cyperi, ligusticum wallichii, rhizoma corydalis, szechwan Chinaberry fruit, fingered citron, costustoot, caulis perllae, arrowroot, cortex albiziae, salviae miltiorrhizae, sandalwood, fructus amomi, flos carthami, ucid ganoderma, myrrh, mint and dried radix rehmanniae. After patients take the traditional Chinese medicine preparation disclosed by the invention, blood meridians of whole bodies are dredged; abdominal distension disappears; the urine volume and exhaust are increased; food intake is increased; after most of patients take the traditional Chinese medicine preparation for about two months, the liver function can be obviously improved; and ascites symptoms disappear. A clinical research proves that the efficacies of tonifying the spleen, promoting blood circulation to remove blood stasis, softening the liver and the like are scientifically combined together on the basis of experience of the ancients in the treatment scheme; and the traditional Chinese medicine preparation has the effects of improving clinical symptoms and signs, protecting the liver, lowering enzyme, adjusting protein metabolism of the liver and resisting liver fibrosis.

Description

A kind of Chinese medicine preparation for the treatment of liver cirrhosis
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation for the treatment of liver cirrhosis.
Background technology
Liver cirrhosis is a kind of common chronic hepatopathy of serious harm health, can cause liver injury by one or more reasons, and liver is Progressive symmetric erythrokeratodermia, diffusivity, fibrous lesions.Be embodied in hepatocyte diffusivity degeneration necrosis, then there is proliferation of fibrous tissue and the regeneration of liver cell nodules shape, these three kinds change repeatedly staggered carrying out, and result lobules of liver structure and blood circulation path reconstructs gradually, make liver distortion, hardening and cause liver cirrhosis.
The onset of liver cirrhosis and differing greatly of evolution process, but majority is comparatively slow, can lays dormant for years, and its great majority are developed by viral hepatitis (mainly hepatitis B and hepatitis C), and sickness rate has and increases trend gradually in recent years.Early stage at liver cirrhosis, when compensatory abundant the and stable disease of liver function, clinical symptoms and sign often lack, along with disease progression, liver function injury increases the weight of, and engenders that function loses compensatory performance, as there is jaundice intensification, ascites, hemorrhage etc., if the state of an illness continues development, there will be the complication such as splenomegaly companion portal hypertension, digestive tract hemorrhage, hepatic encephalopathy, can there is canceration in small number of patients.
Motherland's traditional Chinese medical science thinks that liver cirrhosis belongs to " long-pending card ", the category of " tympanites ".Liver cirrhosis mostly is with the passing of time protracted inflammation, and healthy energy benefit is damaged and formed blood stasis due to qi deficiency, irritability stasis, and catharsis is lacked of proper care.Motherland's medical science thinks that the invasion and attack of liver cirrhosis polyphyly epidemic disease caused by damp-heat pathogen poison cause liver spleen two wound, and hepatopathy is qi depression to blood stasis then, sering stasis blocking; The splenopathy is strong fortune mistake department then, clear YANG failing to ascend, and essence of water and grain can not defeated cloth, water is wet can not be transmitted to drain external, mixes mutually, then block to sering and form ascites so pure and impure, its disease aversion to cold is timid cold, soreness of the waist and knees, yellowish complexion is simple and unadorned, down in spirits, diet is thought less, abdominal distention loose stool, the fat tender or fat purple of light red tongue, the how heavy string of arteries and veins and thin.
Although the Western medicine of current treatment liver cirrhosis is many, toxic and side effects is large, and most of curative effect is still certainly difficult.Hepatocirrhosis in Chinese Herbal Medicine is with a long history, and really can improve symptom and liver function, safety is higher, and curative effect is gratifying.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides the Chinese medicine preparation of a kind of good effect, safe and reliable treatment liver cirrhosis.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for liver cirrhosis, it is characterized in that, described Chinese medicine preparation is made up of the Chinese medicine of following weight portion:
Rhizoma Chuanxiong 5-15 gram, Aloe 10-20 gram, ove Notarchi 2-10 gram, Fructus Gleditsiae Abnormalis 5-15 gram, Thallus Laminariae (Thallus Eckloniae) 5-15 gram, velamen of Tripterygium wilfordii 4-16 gram, Rhizoma Pinelliae 6-14 gram, raw army 10-20 gram, Semen Sinapis Albae 5-15 gram, Radix Gentianae 10-20 gram, Herba Asari 5-15 gram, Rhizoma Curcumae Longae 5-15 gram, Radix Ginseng Rubra 10-20 gram, Herba Hedyotidis Diffusae 10-30 gram, Indigo Naturalis 5-25 gram, Herba Lycopi 2-10 gram, Fructus Amomi 3-9 gram, Radix Curcumae 5-15 gram, Oletum Trogopterori 5-15 gram, Fructus Aurantii Immaturus 5-15 gram, Fructus Amomi Rotundus 4-16 gram, Herba Artemisiae Scopariae 3-17 gram.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the raw material of Chinese medicine of following weight portion:
Rhizoma Chuanxiong 5 grams, Aloe 10 grams, ove Notarchi 2 grams, Fructus Gleditsiae Abnormalis 5 grams, Thallus Laminariae (Thallus Eckloniae) 5 grams, velamen of Tripterygium wilfordii 4 grams, the Rhizoma Pinelliae 6 grams, raw army 10 grams, Semen Sinapis Albae 5 grams, Radix Gentianae 10 grams, Herba Asari 5 grams, 5 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 10 grams, Herba Hedyotidis Diffusae 10 grams, Indigo Naturalis 5 grams, Herba Lycopi 2 grams, Fructus Amomi 3 grams, Radix Curcumae 5 grams, Oletum Trogopterori 5 grams, Fructus Aurantii Immaturus 5 grams, 4 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 3 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the raw material of Chinese medicine of following weight portion:
Rhizoma Chuanxiong 15 grams, Aloe 20 grams, ove Notarchi 10 grams, Fructus Gleditsiae Abnormalis 15 grams, Thallus Laminariae (Thallus Eckloniae) 15 grams, velamen of Tripterygium wilfordii 16 grams, the Rhizoma Pinelliae 14 grams, raw army 20 grams, Semen Sinapis Albae 15 grams, Radix Gentianae 20 grams, Herba Asari 15 grams, 15 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 20 grams, Herba Hedyotidis Diffusae 30 grams, Indigo Naturalis 25 grams, Herba Lycopi 10 grams, Fructus Amomi 9 grams, Radix Curcumae 15 grams, Oletum Trogopterori 15 grams, Fructus Aurantii Immaturus 15 grams, 16 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 17 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the raw material of Chinese medicine of following weight portion:
Rhizoma Chuanxiong 10 grams, Aloe 15 grams, ove Notarchi 6 grams, Fructus Gleditsiae Abnormalis 10 grams, Thallus Laminariae (Thallus Eckloniae) 10 grams, velamen of Tripterygium wilfordii 10 grams, the Rhizoma Pinelliae 10 grams, raw army 15 grams, Semen Sinapis Albae 10 grams, Radix Gentianae 15 grams, Herba Asari 10 grams, 10 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 15 grams, Herba Hedyotidis Diffusae 20 grams, Indigo Naturalis 15 grams, Herba Lycopi 6 grams, Fructus Amomi 6 grams, Radix Curcumae 10 grams, Oletum Trogopterori 10 grams, Fructus Aurantii Immaturus 10 grams, 10 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 10 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the raw material of Chinese medicine of following weight portion:
Get 100 grams after Chinese medicine in described prescription mixes by weight, add water 800 milliliters, decoct to 400 milliliters, elimination medicinal residues, obtain oral administration solution.
Wherein:
Rhizoma Chuanxiong, pungent loose temperature is led to, and has blood-activating and qi-promoting, effect of wind-expelling pain-stopping.The diseases such as Rhizoma Chuanxiong effect is extensive, is applicable to the disease of various stagnation of blood stasis, can be used for menoxenia, amenorrhea dysmenorrhea, and lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, the pain over the hypochondriac region that rheumatic arthralgia and chronic hepatitis, liver and gall diseases cause.
Aloe, has heart tonifying to invigorate blood circulation, and lets out under stomach invigorating, effect of sterilization antiinflammatory.Aloe contains multivitamin (A, Bl, B2, Bo, B12), aminoacid and mineral, energy adjusting immunity of human body (i.e. resistance), health invigorating; Promote cell regeneration, tissue that is injured and sclerosis is got well; Blood circulation promoting, gets rid of vivotoxin.
Ove Notarchi, sweet in the mouth is salty, cold in nature.Return lung, kidney channel.There is clearing away heat and nourishing YIN, the effect of softening the hard mass expectorant, cure mainly the dryness of the lung and breath with cough, epistaxis, goiter, scrofula, eye inflammation.
Fructus Gleditsiae Abnormalis, acrid in the mouth, has consciousness restoring, and edema of the dorsum of the foot pain disappears, and tells effect that wind-phlegm is wonderful, for apoplexy locked mouth, remains unconscious, epilepsy abundant expectoration, and pass key is obstructed, and sore throat stagnation of phlegm, pertinacious phlegm is breathed with cough, the diseases such as not well, constipation due to dry stool of coughing up phlegm.
Thallus Laminariae (Thallus Eckloniae) is salty, cold.Return spleen, liver, kidney channel.There is vanishing sputum and dispelling knot, inducing diuresis to remove edema effect, for goiter, scrofula, edema, the cards such as beriberi edema.The comparatively strong and safety non-toxic of the power of Thallus Laminariae (Thallus Eckloniae) vanishing sputum and dispelling knot, kindly controls the stagnant meridians of expectorant, all cards of pent-up in bulk especially.
Velamen of Tripterygium wilfordii, bitter, acrid, cold.Return liver, kidney channel, wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain, parasite killing detoxifies.For rheumatoid arthritis stubborn, leprosy, stubborn dermatitis, eczema, scabies, dermatitis, erythra, furuncle swelling toxin.
The Rhizoma Pinelliae, has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, effect of dissolving lump and resolving mass, cures mainly cough with asthma abundant expectoration, and vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, has a headache dizzy, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug.
Raw army, have removing the relative excess heat, removing mass is stagnant, the effect of clots absorbing blood, cures mainly excess-heat constipation, and food stagnation is stagnated, stomachache, acute appendicitis, acute infectious hepatitis, blood stasis amenorrhea, toothache, epistaxis, acute conjunctivitis.
Semen Sinapis Albae, acrid in the mouth, warm in nature.Have and reduce phlegm by drink, mass dissipating and swelling eliminating, effect of removing obstruction in the collateral to relieve pain, cure mainly cough with asthma abundant expectoration, fullness in the chest and hypochondriac pain, arthralgia, multiple abscess caused by damp-phlegm, carbuncle of yin nature toxic swelling, regurgitation is vomitted, aphasia due to apoplexy, the diseases such as numb limbs and tense tendons.
Radix Gentianae, bitter in the mouth, cold in nature.Return liver, gallbladder meridian.Have heat clearing and damp drying, the effect of eliminating pathogen in the liver gallbladder excess-fire, cures mainly hypertension, dizziness and tinnitus, cholecystitis, acute infectious hepatitis, jaundice due to damp-heat, furuncle carbuncle, the disease such as bitter taste and infantile convulsion, is the good medicine of hepatic cholagogic.
Herba Asari, nature and flavor are pungent, temperature.Have expelling wind and cold, row water is had one's ideas straightened out, and effect of antalgic cures mainly air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, the diseases such as rheumatic arthralgia.
Rhizoma Curcumae Longae, pungent, bitter, temperature.Return spleen, Liver Channel.Can circulation of qi promoting removing blood stasis with potent drugs, inducing menstruation to relieve menalgia, cures mainly chest and abdomen swelling and pain, shoulder arm arthralgia pain, unbearably pained, puerperal blood pain, skin ulcer tinea onset, menoxenia, amenorrhea, lump in the abdomen, traumatic injury.
Radix Ginseng Rubra is sweet, be slightly cold.Have QI invigorating and blood producing, tonifying the lung nourish heart, effect of tonifying kidney and nourishing yin, take Radix Ginseng Rubra for a long time and can improve body immunity, resisting fatigue, radioprotective, Tumor suppression, adjustment human endocrine system.Radix Ginseng Rubra has the power of the sun that shakes, be specially adapted to asthma unable, decrepit, after being ill weakling take.
Herba Hedyotidis Diffusae, heat-clearing and toxic substances removing, diuresis of blood circulation promoting, for tonsillitis, pharyngolaryngitis, urinary tract infection, pelvic inflammatory disease, appendicitis, hepatitis, bacillary dysentery, venom, tumor.Also can be used for alimentary tract cancer.Modern pharmacology research proves, the immunity of Hedyotidis Diffusae energy enhancing body, the growth of inhibition tumor cell, has inhibitory action to pathogenic bacterium such as bacillus pyocyaneus, staphylococcus aureus, streptococcus pneumoniae, dysentery bacteriums.
Indigo Naturalis, salty, cold.Return liver, lung meridian.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion, diseases such as being used for the treatment of maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared and acute icterohepatitis, acute pelvic inflammatory disease, alleviation Cardiac and esophageal carcinoma block.Indigo Naturalis has anticancer bactericidal action, and the effective ingredient contained by it is indigo certain hepatoprotective effect.
Herba Lycopi, bitter, pungent, tepor.Return liver, spleen channel, have blood circulation promoting and blood stasis dispelling, effect of line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, edema.
Fructus Amomi, acrid in the mouth, warm in nature.Return spleen channel, stomach warp, kidney channel.Have removing dampness to whet the appetite, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy, cures mainly turbid damp obstructing in middle-JIAO, and gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Radix Curcumae, has promoting QI circulation for relieving depression, effect of removing heat from blood removing blood stasis with potent drugs, cures mainly all pains of breast abdomen side of body rib, loses the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.
Oletum Trogopterori, sweet, temperature.Have promoting blood circulation to remove blood stasis, removing toxic substances, effect of spleen invigorating removing food stagnancy, has a pain for trusted subordinate's congestion, blood-stasis internal-depression, escape of blood from meridian hemorrhage, controls all pains of trusted subordinate's vim and vigour, dysmenorrhea, amenorrhea, stomachache, colic, metrorrhagia, menorrhagia, traumatic injury.
Fructus Aurantii Immaturus is bitter, pungent, cold.Spleen channel; Stomach warp; Liver Channel; Heart channel.There is dispelling the stagnated QI removing food stagnancy, reduce phlegm except effect of painful abdominal mass, cure mainly in stagnating and stop, feeling of fullness distending pain, constipation, heavy after dysentery, blocked-up chest, gastroptosis, uterine prolapse, the diseases such as proctoptosis.
Fructus Amomi Rotundus, pungent, temperature.Return lung, spleen, stomach warp.Have removing dampness to disappear painful abdominal mass, circulation of qi promoting warming middle-JIAO, effect of appetite-stimulating indigestion-relieving, for turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Herba Artemisiae Scopariae, cold nature, bitter in the mouth, pungent.Return spleen, stomach, liver, gallbladder meridian.There is clearing away heat-damp and promoting diuresis, effect of jaundice eliminating, cure mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis.Herba Artemisiae Scopariae has significant hepatoprotective effect, to first, and hepatitis B, icterohepatitis, has significant curative effect; There is function of gallbladder promoting, promote bile secretion, increase the effect that in bile, cholic acid and bilirubin are discharged; Can increase heart coronary flow, improve microcirculation, and have blood pressure lowering, blood fat reducing, anticoagulation, diuresis is antipyretic relievings asthma, and drives away ascarid and suppresses the effect of multiple pathogenic dermatophytes and antibacterial.
Chinese medicine preparation of the present invention take determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs as this, it is the evolution that follow wet, hot, strongly fragrant, the stasis of blood, poison according to hepatopathy, through clinical experience, probe boldly after conscientious research, screening constitutes effective prescription of the primary treatment posthepatitic cirrhosis of " blood circulation promoting and blood stasis dispelling, soft contracting liver spleen, softening the hard mass diuretic ".
The water decoction of medicine of the present invention, has heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting, effect that inducing diuresis for treating stranguria syndrome, suppressing the hyperactive liver are regulated the flow of vital energy, meanwhile, the Therapeutic Method that the traditional Chinese medical science is stressed yin-yang and five elements and counteracted each other, and in the traditional Chinese medical science, kidney belongs to the main bone of water, the main muscle of the liver belonging to wood, water generating wood, therefore support kidney or conditioning kidney, when treating the symptom of liver cirrhosis, there is the act of removing burning wood away under the boiler; Equally, the adjustment of liver and gallbladder, liver and spleen and physical therapy, also follow same principle, thus reach table, this is doublely controlled!
After taking Chinese medicine preparation of the present invention, namely patient dredges whole body QI and blood passages through which vital energy circulates within a couple of days, and abdominal distention disappears thereupon, urine volume, and aerofluxus increases, and diet increases, and most of patients about two months liver functions can obviously be improved, ascites transference cure.Clinical research shows, spleen invigorating, blood circulation promoting and blood stasis dispelling, soft liver etc., on the experiential basis of ancients, scientifically combine by this therapeutic scheme, has the effect improving clinical symptoms and sign, the liver protecting and ALT lowering, the metabolism of adjustment liver protein, anti-hepatic fibrosis.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, add water 800 milliliters, decoct to 400 milliliters, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, bfore meals, surrounding is a course for the treatment of.
In addition, Chinese medicine preparation of the present invention, good effect, has no side effect, and the routine various headache statistics of clinical treatment 98 shows, overall clinical efficacy rate reaches 95.9%.
In order to observe the clinical efficacy of Chinese medicine preparation of the present invention treatment posthepatitic cirrhosis, we have chosen 98 routine Patients with Cirrhosis After Hepatitis, it is divided into two groups at random, adopt Chinese medicine preparation of the present invention, routine of western medicine therapy to treat respectively, and observation is compared to both treatment curative effect and clinical symptoms.
In the routine Patients with Cirrhosis After Hepatitis of method 98, treatment group 49 example, male 30 example, women 19 example, minimum 36 years old of age, maximum 59 years old, mean age 48.87 scholar 6.38 years old; Matched group 49 example, male 31 example, women 18 example, minimum 35 years old of age, maximum 57 years old, mean age 49.63 scholar 5.96 years old.The sex of two groups of patients, age, symptom, sign and lab testing, through statistical procedures there was no significant difference (P > 0.05), have comparability.
Inclusive criteria: 1. hepatitis history is more than half a year.2. liver function is abnormal.3. liver (spleen) is kowtowed and touches B ultrasonic prompting enlargement.4. liver cirrhosis is early stage, and ascites is not obvious.5. patient meets liver cirrhosis Western medicine diagnose standard and Liver of TCM spleen two is hindered, pyretic toxicity stasis person; 6. the liver cirrhosis that non-viral hepatitis causes is got rid of, cirrhosis patients in decompensation, alcoholic.
Symptom and sign and lab testing:
1. the visible shallow complexion of patient, jaundice, liver palm, spider angioma, how with weak, indigestion and loss of appetite, inappetence, feels sick, costalgia, oliguria, edema, and tongue fur pulse condition also has abnormal change; 2. lab testing: plasma albumin reduces, and globulin increases, A/G is inverted, and leukocyte and platelet reduce; 3. imaging examination prompting have spleen enlargement in various degree or splenoportal venous broadening, esophagus, varices of fundus of stomach are shown in gastroscopy.
Curative effect determinate standard
With reference to " dropsy " criterion of therapeutical effect in " Chinese medical disease diagnosis and treatment standard and prescription are selected ".Basic healing: ascites is eliminated, and liver function is normal, ultrasound diagnosis: in liver, echo attenuates, and thickness of spleen is normal.Effective: ascites is eliminated, liver function takes a turn for the better, and some projects are normal, and B ultrasonic shows: liver internal echo slightly increases thick enhancing, and spleen is bigger, non-evident sympton.Take a turn for the better: ascites reduces, and liver function slightly takes a turn for the better, B ultrasonic: liver changes of echo is little, and spleen slightly reduces, and symptom alleviates.Invalid: various symptom is not improved.
Therapeutic Method two groups all gives conventional rest, nutrition (give less salt, high protein, low fat diet, supplement vitamin B group, vitamin C, vitamin E etc.), and conventional liver protecting therapy, prevents and treats complication.1. treatment group gives prescription, 3 months courses for the treatment of, observes for 1 course for the treatment of.2. matched group adopts general process to maintain soda acid electrolyte balance; If transaminase raises, diammonium glycyrrhizinate 150mg can be given or become a fine day sweet and refreshing 100mg, qd quiet the liver protecting and ALT lowering; If patient's viral DNA is greater than 105, lamivudine or the treatment of Entecavir oral antiviral can be given, 3 months courses for the treatment of, observed for 1 course for the treatment of.
Result:
Treatment group total effective rate is 95.9%; Matched group total effective rate 77.6%.Conclusion Chinese medicine preparation treatment of the present invention hepatitis cirrhosis better effects if, two groups of patient treatment outcome and comparitive study are in table 1.
Table 1 therapeutic outcome and comparitive study, example (%)
Note: compare between group (p < 0.05)
Table 2 is treated front and back cardinal symptom and is improved situation
Poor appetite Feel sick Weak Costalgia Abdominal distention
Before treatment group treatment 43 25 48 28 46
After treatment 11 3 15 6 12
Before treatment of control group 41 26 45 29 45
After treatment 12 10 16 11 18
Note: compare between group (p < 0.05)
Untoward reaction or side effect: two groups have no anaphylaxis, and routine blood test, renal function have no change; Matched group has 3 examples to occur diarrhoea.
Conclusion: clinical practice shows, Chinese medicine preparation treatment posthepatitic cirrhosis Be very effective of the present invention, cure rate can reach 95.9%, improve patient clinical symptom obvious, and safety is good, without obvious side reaction, is obviously better than pure western medicine.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of liver cirrhosis, choose Rhizoma Chuanxiong 5 grams, Aloe 10 grams, ove Notarchi 2 grams, Fructus Gleditsiae Abnormalis 5 grams, Thallus Laminariae (Thallus Eckloniae) 5 grams, velamen of Tripterygium wilfordii 4 grams, the Rhizoma Pinelliae 6 grams, raw army 10 grams, Semen Sinapis Albae 5 grams, Radix Gentianae 10 grams, Herba Asari 5 grams, 5 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 10 grams, Herba Hedyotidis Diffusae 10 grams, Indigo Naturalis 5 grams, Herba Lycopi 2 grams, Fructus Amomi 3 grams, Radix Curcumae 5 grams, Oletum Trogopterori 5 grams, Fructus Aurantii Immaturus 5 grams, 4 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 3 grams, get 100 grams after mixing and add water 800 milliliters, decoct to 400 milliliters, every day potion, every day three times, each 130 milliliters, bfore meals, surrounding is a course for the treatment of.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of liver cirrhosis, choose Rhizoma Chuanxiong 15 grams, Aloe 20 grams, ove Notarchi 10 grams, Fructus Gleditsiae Abnormalis 15 grams, Thallus Laminariae (Thallus Eckloniae) 15 grams, velamen of Tripterygium wilfordii 16 grams, the Rhizoma Pinelliae 14 grams, raw army 20 grams, Semen Sinapis Albae 15 grams, Radix Gentianae 20 grams, Herba Asari 15 grams, 15 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 20 grams, Herba Hedyotidis Diffusae 30 grams, Indigo Naturalis 25 grams, Herba Lycopi 10 grams, Fructus Amomi 9 grams, Radix Curcumae 15 grams, Oletum Trogopterori 15 grams, Fructus Aurantii Immaturus 15 grams, 16 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 17 grams, get 100 grams after mixing and add water 800 milliliters, decoct to 400 milliliters, every day potion, every day three times, each 130 milliliters, bfore meals, surrounding is a course for the treatment of.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of liver cirrhosis, choose Rhizoma Chuanxiong 10 grams, Aloe 15 grams, ove Notarchi 6 grams, Fructus Gleditsiae Abnormalis 10 grams, Thallus Laminariae (Thallus Eckloniae) 10 grams, velamen of Tripterygium wilfordii 10 grams, the Rhizoma Pinelliae 10 grams, raw army 15 grams, Semen Sinapis Albae 10 grams, Radix Gentianae 15 grams, Herba Asari 10 grams, 10 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 15 grams, Herba Hedyotidis Diffusae 20 grams, Indigo Naturalis 15 grams, Herba Lycopi 6 grams, Fructus Amomi 6 grams, Radix Curcumae 10 grams, Oletum Trogopterori 10 grams, Fructus Aurantii Immaturus 10 grams, 10 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 10 grams, get 100 grams after mixing and add water 800 milliliters, decoct to 400 milliliters, every day potion, every day three times, each 130 milliliters, bfore meals, surrounding is a course for the treatment of.
Some patients healing case is as follows:
Tang, female, 53 years old, patient's readme occurred that from the year before last red urine is short of, and constipation is indigestion and loss of appetite, abdominal distention, weak, the jaundice in the whole body, the symptom such as to be off one's feed, because Hepatocirrhosis is at certain hospitalize two wheat harvesting period, because curative effect does not show, Chinese medicine preparation of the present invention is used instead after leaving hospital, every day, potion, divided morning, noon and afternoon to take for three times, after half course for the treatment of, above-mentioned symptom is alleviated to some extent, jaundice disappears substantially, and appetite is obviously improved, and conscious spirit is strong, after continuing to take two courses for the treatment of, all diseases disappear, and health recovers normal substantially, follows up a case by regular visits to and has no recurrence.
In certain, man, 58 years old, patient feels intermittent distending pain when starting to occur right rib before 5 years, inappetence, oliguria, the symptoms such as abdominal distention, to examination in hospital, liver function test is abnormal, be diagnosed as cirrhotic ascites is early stage, western modern medicine treats three months subjective symptomss, sign and liver function test are all without improvement, use Chinese medicine preparation of the present invention instead, after taking a course for the treatment of, voided volume time showed increased, abdominal distention, costalgia alleviates, abdominal circumference reduces, after take again two courses for the treatment of, diet increases, two just, abdominal circumference recovers normal, liver and spleen retraction or the deliquescing that obviously bounces back, jaundice, ascites disappears, liver function test is normal, light physical labor can be engaged in, follow up a case by regular visits to and have no recurrence.
River, man, 39 years old, this patient is conscious before 3 years there is general weakness without clear and definite inducement, particularly two lower limb are more obvious, can alleviate after rest, there is jaundice, weak, feel sick, the symptoms such as vomiting and inappetence, sometimes also to turn sour with back and extremities joint is ached, hepatitis C liver cirrhosis is diagnosed as to examination in hospital, adopt western medicine, effect does not show, then Chinese medicine preparation of the present invention treatment is used, every day potion, the morning, noon and afternoon are divided to take for three times, after taking one week, feel sick, symptoms of emesis disappears, continue to take two courses for the treatment of, back, extremity pain disappears, patient identifies oneself to brace up, appetite increases, health recovers normal substantially, stable disease is more than half a year, follow up a case by regular visits to and have no recurrence.

Claims (4)

1. treat a Chinese medicine preparation for liver cirrhosis, it is characterized in that, described Chinese medicine preparation is made up of the Chinese medicine of following weight portion:
Rhizoma Chuanxiong 5-15 gram, Aloe 10-20 gram, ove Notarchi 2-10 gram, Fructus Gleditsiae Abnormalis 5-15 gram, Thallus Laminariae (Thallus Eckloniae) 5-15 gram, velamen of Tripterygium wilfordii 4-16 gram, Rhizoma Pinelliae 6-14 gram, raw army 10-20 gram, Semen Sinapis Albae 5-15 gram, Radix Gentianae 10-20 gram, Herba Asari 5-15 gram, Rhizoma Curcumae Longae 5-15 gram, Radix Ginseng Rubra 10-20 gram, Herba Hedyotidis Diffusae 10-30 gram, Indigo Naturalis 5-25 gram, Herba Lycopi 2-10 gram, Fructus Amomi 3-9 gram, Radix Curcumae 5-15 gram, Oletum Trogopterori 5-15 gram, Fructus Aurantii Immaturus 5-15 gram, Fructus Amomi Rotundus 4-16 gram, Herba Artemisiae Scopariae 3-17 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese medicine of following weight portion:
Rhizoma Chuanxiong 5 grams, Aloe 10 grams, ove Notarchi 2 grams, Fructus Gleditsiae Abnormalis 5 grams, Thallus Laminariae (Thallus Eckloniae) 5 grams, velamen of Tripterygium wilfordii 4 grams, the Rhizoma Pinelliae 6 grams, raw army 10 grams, Semen Sinapis Albae 5 grams, Radix Gentianae 10 grams, Herba Asari 5 grams, 5 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 10 grams, Herba Hedyotidis Diffusae 10 grams, Indigo Naturalis 5 grams, Herba Lycopi 2 grams, Fructus Amomi 3 grams, Radix Curcumae 5 grams, Oletum Trogopterori 5 grams, Fructus Aurantii Immaturus 5 grams, 4 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 3 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese medicine of following weight portion:
Rhizoma Chuanxiong 15 grams, Aloe 20 grams, ove Notarchi 10 grams, Fructus Gleditsiae Abnormalis 15 grams, Thallus Laminariae (Thallus Eckloniae) 15 grams, velamen of Tripterygium wilfordii 16 grams, the Rhizoma Pinelliae 14 grams, raw army 20 grams, Semen Sinapis Albae 15 grams, Radix Gentianae 20 grams, Herba Asari 15 grams, 15 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 20 grams, Herba Hedyotidis Diffusae 30 grams, Indigo Naturalis 25 grams, Herba Lycopi 10 grams, Fructus Amomi 9 grams, Radix Curcumae 15 grams, Oletum Trogopterori 15 grams, Fructus Aurantii Immaturus 15 grams, 16 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 17 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese medicine of following weight portion:
Rhizoma Chuanxiong 10 grams, Aloe 15 grams, ove Notarchi 6 grams, Fructus Gleditsiae Abnormalis 10 grams, Thallus Laminariae (Thallus Eckloniae) 10 grams, velamen of Tripterygium wilfordii 10 grams, the Rhizoma Pinelliae 10 grams, raw army 15 grams, Semen Sinapis Albae 10 grams, Radix Gentianae 15 grams, Herba Asari 10 grams, 10 grams, Rhizoma Curcumae Longae, Radix Ginseng Rubra 15 grams, Herba Hedyotidis Diffusae 20 grams, Indigo Naturalis 15 grams, Herba Lycopi 6 grams, Fructus Amomi 6 grams, Radix Curcumae 10 grams, Oletum Trogopterori 10 grams, Fructus Aurantii Immaturus 10 grams, 10 grams, Fructus Amomi Rotundus, Herba Artemisiae Scopariae 10 grams.
CN201510765756.XA 2015-11-11 2015-11-11 Traditional Chinese medicine preparation for treating liver cirrhosis Pending CN105194588A (en)

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CN101130001A (en) * 2007-08-28 2008-02-27 尹克山 Traditional Chinese medicine for treating early cirrhosis
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190100879A (en) * 2018-02-21 2019-08-29 경북대학교 산학협력단 Composition for preventing, treating or improving obesity or obesity-related disease comprising extracts of Mentha arvensis var. piperascens
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Application publication date: 20151230