CN101612291B - Medicine composition for treating psoriasis - Google Patents

Medicine composition for treating psoriasis Download PDF

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Publication number
CN101612291B
CN101612291B CN2009100174002A CN200910017400A CN101612291B CN 101612291 B CN101612291 B CN 101612291B CN 2009100174002 A CN2009100174002 A CN 2009100174002A CN 200910017400 A CN200910017400 A CN 200910017400A CN 101612291 B CN101612291 B CN 101612291B
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radix
parts
portions
rhizoma
herba
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CN101612291A (en
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迟心勇
迟志明
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Abstract

The invention discloses a medicine composition for treating psoriasis, which is prepared by the following raw materials according to the weight portion: 150-200 portions of blackberry lily, 300-400 portions of subprostrate sophora, 200-300 portions of honeysuckle, 150-200 portions of cotex dictamni, 300-600 portions of china root, 100-200 portions of paris polyphylla, 300-500 portions of oldenlandia diffusa, 200-300 portions of herba scutellariae barbatae, 300-400 portions of radix arnebiae seu lithospermi, 150-200 portions of ebony, 150-200 portions of nutgall, 300-500 portions of hoantchy root, 300-500 portions of motherwort, 100-200 portions of rhubarb, 200-300 portions of salvia miltiorrhiza and 150-200 portions of liquorice. The invention is prepared by pure Chinese medicinal herbs and has remarkable treatment effect and no side effect to the patient; it is clinically proved that the cure rate reaches more than 90 percent without easy recrudescence.

Description

The psoriatic pharmaceutical composition of a kind of treatment
Technical field
The invention belongs to field of medicaments, relate in particular to the psoriatic pharmaceutical composition of a kind of treatment.
Background technology
Psoriasis is a kind of common inflammation dermatoses, is the disease of principal character with skin generation squama skin lesion, and clinical manifestation is red pimple or speckle, and skin surface covers silvery white squama, causes the local skin thickening, is commonly called as psoriasis.According to psoriatic clinical and pathological characters, generally can be divided into homeliness type, arthritis type, pustule type, the treatment psoriasis does not still have effective ways now, adopt following several drugs therapy mostly: the one, methotrexate, be anti-folic acid class antineoplastic agent, be relatively early to be used for the treatment of psoriatic cell toxicity medicament, be applicable to arthritis type, erythrodermic, psoriasis pustulosa and general property psoriasis vulgaris, this medicine is heavier to the toxic reaction of liver, can cause the extensive fibrosis and the liver cirrhosis of liver, hemopoietic system is had inhibitory action, mainly show leukopenia, also influential to platelet, can there be whole blood to descend when serious; The 2nd, ethyliminum claims Ethylenediamine Tetraacetylimine again, mainly is suppress the interior DNA (deoxyribonucleic acid) of cell synthetic, thereby produces cytostatic effect, and its major side effects is bone marrow depression, causes leukopenia and platelet to descend; The 3rd, corticosteroid hormone, although corticosteroid hormone is treated each psoriasis pustulosa curative effect is preferably arranged, application dose is bigger, and the time is longer, can cause serious hormone side effect, and after decrement or drug withdrawal, cause serious psoriasis recurrence or become psoriasis pustulosa.
Summary of the invention
The invention provides the psoriatic pharmaceutical composition of a kind of treatment, solved the drug treatment of taking in the background technology patient body is caused serious adverse, easily the shortcoming of recurrence.
Technical scheme of the present invention is achieved in that the psoriatic pharmaceutical composition of a kind of treatment, the medicament of making by the following weight proportion raw material: Rhizoma Belamcandae 150-200 part, Radix Sophorae Tonkinensis 300-400 part, Flos Lonicerae 200-300 part, Cortex Dictamni 150-200 part, Rhizoma Smilacis Glabrae 300-600 part, Rhizoma Paridis 100-200 part, Herba Hedyotidis Diffusae 300-500 part, Herba Scutellariae Barbatae 200-300 part, Radix Arnebiae (Radix Lithospermi) 300-400 part, Fructus Mume 150-200 part, Galla Chinensis 150-200 part, Radix Astragali 300-500 part, Herba Leonuri 300-500 part, Radix Et Rhizoma Rhei 100-200 part, Radix Salviae Miltiorrhizae 200-300 part, Radix Glycyrrhizae 150-200 part;
The present invention is the medicament of being made by following better materials of weight proportions: Rhizoma Belamcandae 160-190 part, Radix Sophorae Tonkinensis 350-390 part, Flos Lonicerae 240-280 part, Cortex Dictamni 160-190 part, Rhizoma Smilacis Glabrae 400-500 part, Rhizoma Paridis 120-180 part, Herba Hedyotidis Diffusae 350-450 part, Herba Scutellariae Barbatae 220-280 part, Radix Arnebiae (Radix Lithospermi) 320-380 part, Fructus Mume 160-190 part, Galla Chinensis 160-190 part, Radix Astragali 350-450 part, Herba Leonuri 350-450 part, Radix Et Rhizoma Rhei 120-180 part, Radix Salviae Miltiorrhizae 220-280 part, Radix Glycyrrhizae 160-190 part;
The present invention is the medicament of being made by following optimum weight proportion raw material: 180 parts of Rhizoma Belamcandae, 360 parts of Radix Sophorae Tonkinensiss, 260 parts of Flos Loniceraes, 180 parts of Cortex Dictamni, 450 parts of Rhizoma Smilacis Glabraes, 150 parts of Rhizoma Paridis, 400 parts of Herba Hedyotidis Diffusaes, 250 parts of Herba Scutellariae Barbataes, 350 parts of Radix Arnebiae (Radix Lithospermi)s, 180 parts of Fructus Mumes, 180 parts of Galla Chinensiss, 400 parts of the Radixs Astragali, 400 parts of Herba Leonuris, 150 parts of Radix Et Rhizoma Rhei, 250 parts of Radix Salviae Miltiorrhizaes, 180 parts in Radix Glycyrrhizae.
Compound method of the present invention adds cold water with said medicine and soaked 6 hours for 9000 parts, uses very hot oven earlier, changes 1.5 hours at a simmer after being fried boiling, and takes concoction 6000 parts, is the medicament of a course of treatment, and be 20 days each course of treatment.
The effect of selected medicine:
Rhizoma Belamcandae: hardship, cold; Heat-clearing and toxic substances removing, dispelling phlegm and relieving sore-throat has stronger inhibitory action to common pathogenic fungus, and antiinflammatory action is arranged, and has analgesic and analgesic effect.
Radix Sophorae Tonkinensis: hardship, cold.Heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling.
Flos Lonicerae: abnormal smells from the patient is sweet, warm, nontoxic, is heat and toxic materials clearing away medicine, and nature and flavor are sweet, cold, goes into lung, stomach, heart channel, is mainly used in the pyretic toxicity carbuncle sore, has the detoxifcation carbuncle of loosing, the clearing away heat and cooling blood effect, can also swell clearly make eye bright, expelling wind and cold.
Cortex Dictamni: be the perennial perennial root draft of rutaceae, Herb has strong aroma, and the sheep smell of mutton is arranged, and mildly bitter flavor has heat clearing and damp drying, and the antidotal effect of dispeling the wind is used for damp and hot sore, and yellow fluid is dripping, eczema, rubella, jaundice.
Rhizoma Smilacis Glabrae: sweet, light, flat.Return liver, stomach warp.The detoxifcation dehumidifying, easing joint movement.The Fructus Myricae rubrae skin infection, limbs contracture, stranguria with turbid discharge leukorrhagia, damp and hot sore.
Rhizoma Paridis: the flat cold of bitter in the mouth, slightly poisonous, go into Liver Channel.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.
Herba Hedyotidis Diffusae: bitter but sweet flavor, warm in nature, nontoxic.Heat clearing away, dampness removing, detoxifcation.
Herba Scutellariae Barbatae: property is flat, and the little hardship of acrid in the mouth is nontoxic, heat clearing away, detoxifcation, dissipating blood stasis, hemostasis, analgesic therapy.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice is had sore throat, lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.
Radix Arnebiae (Radix Lithospermi): sweet, cold.GUIXIN, Liver Channel.Removing heat from blood and promoting blood circulation, the detoxifcation rash.Cure mainly maculae caused by violent heat pathogen, measles is purple dark, and rash goes out not smooth, ulcer sores, eczema pudendal pruritus, burn due to hot liquid or fire.
Fructus Mume: sour, puckery, flat.Return liver, spleen, lung, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.Be used for chronic cough of deficiency lung, the chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache; Ascariasis of biliary tract.
Galla Chinensis: sour, puckery, cold.Return lung, large intestine, kidney channel.The pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, controlling nocturnal emission with astringent drugs end to be lost, the arresting sweating hemostasis.Cure mainly chronic cough of deficiency lung, the lung-heat phlegmatic cough, the chronic diarrhea chronic dysentery, emission and spermatorrhea, spontaneous sweating, metrostaxis, the hemorrhoidal bleeding of having blood in stool, eczema flowing water, ulcer being unable to heal, anus take off does not receive uterine prolapse.
The Radix Astragali: sweet, warm, return spleen, lung meridian, have tonifying Qi and lifting yang, hemopoietic is capable to stagnate, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, the effect of inducing diuresis to remove edema, be used for deficiency of both the splenic and pulmonary QI, sinking of QI of middle-JIAO, fever due to deficiency of blood, cardiopalmus is sallow, blood stagnancy due to deficiency of QI, rheumatic arthralgia, hemiplegia, the exterior deficiency spontaneous perspiration, carbuncle is not burst, burst for a long time and do not hold back, deficiency of vital energy edema, interior-heat is quenched one's thirst.
Herba Leonuri: the little hardship of acrid in the mouth, nontoxic.Invigorate blood circulation, blood stasis dispelling, regulating menstruation, water disappears.Control menoxenia, the vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria is rushed down blood, the carbuncle skin infection.
Radix Et Rhizoma Rhei: hardship, cold.Return spleen, stomach, large intestine, liver, heart channel.Heat and toxic materials clearing away, clearing away heat-fire, hemostasis, detoxifcation, blood circulation promoting and blood stasis dispelling.Cure mainly the excess-heat constipation, stagnant stomachache, dysentery is not well, heat in blood is told nosebleed, the conjunctival congestion pharyngalgia, gingival swelling and pain, pathopyretic ulcer, abdominalgia with intestinal abscess, puerperal stasis of blood pain, blood stasis amenorrhea, traumatic injury, jaundice due to damp-heat, damp-heat gonorrhoea; The external treatment burn due to hot liquid or fire.
Radix Salviae Miltiorrhizae: hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Blood circulation promoting and blood stasis dispelling, the removing heat from blood eliminating carbuncle, relieving restlessness is calmed the nerves.
Radix Glycyrrhizae: sweet in the mouth is flat.With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Process usefulness, control weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion; Give birth to usefulness, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
Using method of the present invention is that Chinese medicine is fried in shallow oil juice, and three times on the one, 100ml for oral administration after meal at every turn washes diseased region with Chinese medicine preparation simultaneously and controls, and 20 days is a course of treatment.
Clinical data: medicine of the present invention is carried out the clinical practice test in a tame hospital above county level, treated 168 routine patients, clinical effectiveness is remarkable, and its clinical data is as follows:
Processing: with Rhizoma Belamcandae, Radix Sophorae Tonkinensis, Flos Lonicerae, Cortex Dictamni, Rhizoma Smilacis Glabrae, Rhizoma Paridis, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Arnebiae (Radix Lithospermi), Fructus Mume, Galla Chinensis, the Radix Astragali, Herba Leonuri, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, prepare in proportion, decoct by the common process of Chinese medicine and make decoction.
Usage: three times on the one, 100ml after meal at every turn, 20 days is a course of treatment.
Physical data: 168 examples of sampling, male's 108 examples wherein, women's 60 examples, age 19-30 year 108 examples, 31-62 year 60 examples, course of disease 1-5 110 examples, 6-11 58 examples.
Criterion of therapeutical effect:
Cure: skin lesion and subjective symptoms disappear entirely, do not have recurrence after 1 year.
Produce effects: skin lesion disappears more than 2/3rds.
Effectively: skin lesion and subjective symptoms are improved less than 1/2nd.
Invalid: skin lesion and subjective symptoms are improved less than 1/5th.
Efficacy result:
In 168 routine patients of sampling, take 102 examples that have of promptly curing for first course of treatment, cure rate reaches 61%, 50 examples of produce effects, removing the patient of healing, 66 remaining examples continued to take second course of treatment, healing 58 examples are arranged, cure rate reaches 88%, 8 examples of produce effects are cured 160 examples after two courses of treatment altogether, and cure rate reaches 96%, 8 examples of produce effects, total effective rate reaches 100%.
The typical case history of taking pharmaceutical composition of the present invention is as follows:
1, Liu * *, man, 26 years old, suffered from psoriasis vulgaris 6 years, through too much tame hospitalize, though symptom alleviated at that time, but after the drug withdrawal soon promptly the recurrence, after take pharmaceutical composition of the present invention, one day three times, each 100ml, erythra is thin out after three days, promptly disappears i.e. recovery from illness in 20 days in 10 days substantially, after continue again to take and consolidate curative effect two courses of treatment, not recurrence in 3 years so far.
2, car * *, the man, 35 years old, suffered from psoriasis 12 years, once treated at large hospitals such as Beijing, Dalian, but the state of an illness still repeatedly, particularly abdominal part is and strips off shape dermatitis, i.e. erythroderma, and play is itched, bring very big misery to patient, after take pharmaceutical composition of the present invention, one day three times, each 100ml, with Chinese medicine preparation of the present invention diseased region is washed simultaneously and controlled, through the treatment of a course of treatment, the skin lesion and the symptom of scratching where it itches significantly alleviate, and fully recover after two courses of treatment, continue to take two after treatments course of treatment, not recurrence in 3 years so far.
3, high * *, woman, 45 years old, suffer from psoriasis pustulosa 15 years, once used the aminopterin hormone medicine, but still outbreak repeatedly of the state of an illness, because of brothers suffer from pustular eruption, rhagadia manus et pedis, work such as do housework is all very difficult, after take pharmaceutical composition of the present invention, one day three times, each 100ml, with Chinese medicine preparation of the present invention diseased region is washed simultaneously and controlled, through the treatment of a course of treatment, symptom significantly alleviates, fully recover after two courses of treatment, continue to take two after treatments course of treatment, not recurrence in 3 years so far.
The invention has the beneficial effects as follows: the present invention adopts pure Chinese medicinal preparation, and is evident in efficacy, patient body do not find that side effect is arranged, and through clinical proof, cure rate reaches more than 90%, is difficult for recurrence.
The specific embodiment:
In order to understand better and to implement, describe the psoriatic pharmaceutical composition of treatment of the present invention in detail below in conjunction with embodiment.
Embodiment 1: accurately take by weighing Rhizoma Belamcandae 20g, Radix Sophorae Tonkinensis 30g, Flos Lonicerae 20g, Cortex Dictamni 20g, Rhizoma Smilacis Glabrae 30g, Rhizoma Paridis 10g, Herba Hedyotidis Diffusae 30g, Herba Scutellariae Barbatae 30g, Radix Arnebiae (Radix Lithospermi) 20g, Fructus Mume 10g, Galla Chinensis 20g, Radix Astragali 30g, Herba Leonuri 30g, Radix Et Rhizoma Rhei 10g, Radix Salviae Miltiorrhizae 20g, Radix Glycyrrhizae 15g, said medicine is added cold water 1000g, soaked 6 hours, use earlier very hot oven, change 1.5 hours at a simmer after being fried boiling, take concoction, dose for potion, be 20 days each course of treatment, three times on the one, each one after each meal 100ml.
Embodiment 2: accurately take by weighing Rhizoma Belamcandae 20g, Radix Sophorae Tonkinensis 20g, Flos Lonicerae 20g, Cortex Dictamni 20g, Rhizoma Smilacis Glabrae 30g, Rhizoma Paridis 10g, Herba Hedyotidis Diffusae 30g, Herba Scutellariae Barbatae 20g, Radix Arnebiae (Radix Lithospermi) 10g, Fructus Mume 10g, Galla Chinensis 20g, Radix Astragali 50g, Herba Leonuri 30g, Radix Et Rhizoma Rhei 10g, Radix Salviae Miltiorrhizae 20g, Radix Glycyrrhizae 10g, said medicine is added cold water 1000g, soaked 6 hours, use earlier very hot oven, change 1 hour at a simmer after being fried boiling, take concoction, dose for potion, be 20 days each course of treatment, three times on the one, each one after each meal 100ml.

Claims (4)

1. treat psoriatic pharmaceutical composition for one kind, it is characterized in that the medicament made by the following weight proportion raw material: Rhizoma Belamcandae 150-200 part, Radix Sophorae Tonkinensis 300-400 part, Flos Lonicerae 200-300 part, Cortex Dictamni 150-200 part, Rhizoma Smilacis Glabrae 300-600 part, Rhizoma Paridis 100-200 part, Herba Hedyotidis Diffusae 300-500 part, Herba Scutellariae Barbatae 200-300 part, Radix Arnebiae (Radix Lithospermi) 300-400 part, Fructus Mume 150-200 part, Galla Chinensis 150-200 part, Radix Astragali 300-500 part, Herba Leonuri 300-500 part, Radix Et Rhizoma Rhei 100-200 part, Radix Salviae Miltiorrhizae 200-300 part, Radix Glycyrrhizae 150-200 part.
2. the psoriatic pharmaceutical composition of a kind of treatment according to claim 1, it is characterized in that the medicament made by following better materials of weight proportions: Rhizoma Belamcandae 160-190 part, Radix Sophorae Tonkinensis 350-390 part, Flos Lonicerae 240-280 part, Cortex Dictamni 160-190 part, Rhizoma Smilacis Glabrae 400-500 part, Rhizoma Paridis 120-180 part, Herba Hedyotidis Diffusae 350-450 part, Herba Scutellariae Barbatae 220-280 part, Radix Arnebiae (Radix Lithospermi) 320-380 part, Fructus Mume 160-190 part, Galla Chinensis 160-190 part, Radix Astragali 350-450 part, Herba Leonuri 350-450 part, Radix Et Rhizoma Rhei 120-180 part, Radix Salviae Miltiorrhizae 220-280 part, Radix Glycyrrhizae 160-190 part.
3. the psoriatic pharmaceutical composition of a kind of treatment according to claim 1 and 2 is characterized in that the medicament of being made by following optimum weight proportion raw material: 180 parts of Rhizoma Belamcandae, 360 parts of Radix Sophorae Tonkinensiss, 260 parts of Flos Loniceraes, 180 parts of Cortex Dictamni, 450 parts of Rhizoma Smilacis Glabraes, 150 parts of Rhizoma Paridis, 400 parts of Herba Hedyotidis Diffusaes, 250 parts of Herba Scutellariae Barbataes, 350 parts of Radix Arnebiae (Radix Lithospermi)s, 180 parts of Fructus Mumes, 180 parts of Galla Chinensiss, 400 parts of the Radixs Astragali, 400 parts of Herba Leonuris, 150 parts of Radix Et Rhizoma Rhei, 250 parts of Radix Salviae Miltiorrhizaes, 180 parts in Radix Glycyrrhizae.
4. according to claim 1 or 2 or 3 described a kind of compound methods for the treatment of psoriatic pharmaceutical composition, said medicine is added cold water soaked 6 hours for 9000 parts, use earlier very hot oven, change 1.5 hours at a simmer after being fried boiling, taking concoction 6000 parts, is the medicament of a course of treatment, and be 20 days each course of treatment.
CN2009100174002A 2009-08-04 2009-08-04 Medicine composition for treating psoriasis Expired - Fee Related CN101612291B (en)

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232894A (en) * 2015-10-21 2016-01-13 刘萍 Traditional Chinese medicine lotion for treating psoriasis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1363350A (en) * 2001-01-02 2002-08-14 刘世刚 Chinese medicine for treating psoriasis
CN101040931A (en) * 2007-04-20 2007-09-26 张秀丽 Chinese traditional medicine took orally for treating psoriasis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1363350A (en) * 2001-01-02 2002-08-14 刘世刚 Chinese medicine for treating psoriasis
CN101040931A (en) * 2007-04-20 2007-09-26 张秀丽 Chinese traditional medicine took orally for treating psoriasis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
孙捷,张虹亚.中医药治疗银屑病的研究进展.《甘肃中医》.2007,第20卷(第7期),95-98. *
黄国坚.银屑病的中西医治疗进展.《山西中医》.2008,第24卷(第4期),54-56. *

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