CN101745047A - Chinese medicinal composition for treating gout disease and preparation method thereof - Google Patents

Chinese medicinal composition for treating gout disease and preparation method thereof Download PDF

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Publication number
CN101745047A
CN101745047A CN201010118768A CN201010118768A CN101745047A CN 101745047 A CN101745047 A CN 101745047A CN 201010118768 A CN201010118768 A CN 201010118768A CN 201010118768 A CN201010118768 A CN 201010118768A CN 101745047 A CN101745047 A CN 101745047A
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chinese medicine
radix
preparation
herba
medicine composition
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张文俊
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Abstract

The invention discloses a Chinese medicinal composition for treating gout disease and a preparation method thereof. The Chinese medicinal composition comprises amur corktree bark, radix stephaniae tetrandrae, coix seed, longhairy antenoron herb, weeping forsythiae capsule, philippine violet herb, honeysuckle flower, spreading hedyotis herb, dahurian patrinia herb, divaricate saposhnikovia root, incised notopterygium rhizome, doubleteeth pubescent angilica root, twotooth achyranthes root, Japanese honeysuckle stem, mulberry twig, earthworm and yanhusuo as the main medicaments. The 17 medicaments have effects of clearing away heat and eliminating dampness, detoxifying and inducing diuresis, and easing joint movement. The Chinese medicinal composition is used for treating gout disease. The Chinese medicinal composition inherits ancestral secret prescriptions, cures numerous patients by practical application of a great number of people, and is announced to the public for promoting the gem of the Chinese medicaments and benefiting mankind.

Description

A kind of Chinese medicine composition and preparation method for the treatment of goat
Technical field
The invention belongs to a kind of Chinese medicine composition in the medicine, especially the treatment goat is had the Chinese medicine composition and the preparation method of obvious curative effects
Background technology
Gout is a purine metabolism obstacle in the human body, will cause uric acid in human body, to deposit and blood in uric acid continue to raise and tissue injury's property disease of causing.Clinical characters is that hyperuricemia is accompanied by that gouty arthritis is shown effect repeatedly, various disease conditions such as when tophus deposition, gouty kidney and dysbolismus pathological changes, shows effect for seeing repeatedly with gouty arthritis more.Along with people's living standard improves, the change of nutrition and diet structure, the gout sickness rate is and obviously increases trend.
The traditional Chinese medical science thinks that the joint meridians that stagnate flow by the resistance of the turbid damp stasis of blood in gout system, and due to QI and blood was smooth, non-general ailment said due to cold or exposure was done.The heresy of turbid damp, non-be subjected in outside, and in main being born in.General patient with gout is mainly in middle-aged and elderly people, plump people, its internal organs degradation, if having a liking for the food greasy and surfeit flavour, infringement function of a specified duration is the most outstanding to damage the pure and impure metabolic function of spleen kidney especially.Dysfunction of the spleen in transportation, ascending the clear and descending the turbid is had no right, the weary gasification of kidney, separating clear and excreting turbid mistake department, water paddy is reforming not, and is living in the turbid poison, blocks up that (the pure and impure metabolism of spleen kidney) is not normal to be only disease originally, and the turbid poison of uric acid is the middle pathological product of pathological changes, and produces disease such as gouty arthritis thus.
The inventor thinks that the cause of disease of gout mainly is that institute causes by " give birth in damp and hot, the turbid poison, diseases caused by retention of fluid is stagnated ", so the rule of treatment is worked as based on heat clearing and damp drying, detoxifcation, diuretic, easing joint movement.
Summary of the invention
The invention provides a kind of Chinese medicine composition, said composition has the effect of heat clearing and damp drying, detoxifcation, diuretic, easing joint movement, is used for the treatment of the Chinese medicine composition of gout.
Another object of the present invention provides the preparation method of above-mentioned Chinese medicine composition.
The present invention is achieved by the following technical solutions, and a kind of Chinese medicine composition, the Chinese medicine of being joined part by following weight are that the drug regimen of raw material is:
Cortex Phellodendri 10--25, Radix Stephaniae Tetrandrae 15--30, Semen Coicis 10--30, Herba Lysimachiae 10--30, Fructus Forsythiae 10--25, Herba Violae 15--30, Flos Lonicerae 15--30, Herba Hedyotidis Diffusae 15--30, Herba Patriniae 15--30, Radix Saposhnikoviae 20--30, Rhizoma Et Radix Notopterygii 15--30, Radix Angelicae Pubescentis 15--30, Radix Achyranthis Bidentatae 20--30, Caulis Lonicerae 20--30, Ramulus Mori 20--30, Pheretima 5--15, Rhizoma Corydalis 20--35.
The drug regimen that the invention belongs to Chinese medicine that a kind of Chinese medicine composition joined part by following weight and be raw material is:
Cortex Phellodendri 13--18, Radix Stephaniae Tetrandrae 23--28, Semen Coicis 13--20, Herba Lysimachiae 13--20, Fructus Forsythiae 15--23, Herba Violae 15--25, Flos Lonicerae 18--25, Herba Hedyotidis Diffusae 18--25, Herba Patriniae 18--23, Radix Saposhnikoviae 23--28, Rhizoma Et Radix Notopterygii 18--30, Radix Angelicae Pubescentis 18--30, Radix Achyranthis Bidentatae 18--30, Caulis Lonicerae 18--30, Ramulus Mori 18--30, Pheretima 8--12, Rhizoma Corydalis 25--32.
The drug regimen that the invention belongs to Chinese medicine that a kind of Chinese medicine composition joined part by following weight and be raw material is:
Cortex Phellodendri 15, Radix Stephaniae Tetrandrae 15, Semen Coicis 15, Herba Lysimachiae 15, Fructus Forsythiae 20, Herba Violae 20, Flos Lonicerae 20, Herba Hedyotidis Diffusae 20, Herba Patriniae 20, Radix Saposhnikoviae 25, Rhizoma Et Radix Notopterygii 25, Radix Angelicae Pubescentis 25, Radix Achyranthis Bidentatae 25, Caulis Lonicerae 25, Ramulus Mori 25, Pheretima 10, Rhizoma Corydalis 30.
Its pharmacology is as follows:
Cortex Phellodendri: bitter cold, return kidney, urinary bladder channel, heat clearing away behaviour is wet, eliminating fire and detoxication, nourishing YIN to lower pathogenic fire.
Radix Stephaniae Tetrandrae: bitter cold, return bladder, lung meridian, inducing diuresis to remove edema, wind-expelling pain-stopping are used for the edema beriberi, damp and hot arthralgia pain, dysuria, brothers' contraction is anxious, diseases such as carbuncle malignant boil.
Semen Coicis: sweet, light, spleen is returned in cold, stomach, and lung meridian has the spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment antidiarrheal function.
Herba Lysimachiae: sweet, salty, be slightly cold, return liver, gallbladder, kidney, urinary bladder channel has heat clearing away, eliminating damp-heat, treating stranguria repercussive effect: be used for pyretic stranguria and urinate puckery pain work, jaundice dark coloured urine, liver knot cholelithiasis, lithangiuria, carbuncle furuncle.
Fructus Forsythiae: hardship, be slightly cold, return lung, the heart, small intestine meridian has heat-clearing and toxic substances removing, the function of dispersing swelling and dissipating binds is used for the treatment of anemofrigid cold, epidemic febrile disease from the beginning of, warmly go into villous themeda, the hyperpyrexia excessive thirst, coma is sent out speckle, pyretic stranguria, urine retention carbuncle, scrofula drop, mastalgia, erysipelas.
Flos Lonicerae: sweet, cold, go into lung, the heart, stomach warp; Heat-clearing and toxic substances removing, the effect of wind-heat dissipating.
Herba Violae: hardship, suffering, cold, GUIXIN, Liver Channel has heat-clearing and toxic substances removing, removing heat from blood repercussive function.Be used for furuncle swelling toxin, carbuncle carbuncle on the back erysipelas etc.
Herba Hedyotidis Diffusae: hardship, sweet, cold, GUIXIN, liver, spleen channel has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, diuretic function, carbuncle furuncle, dyspnea and cough due to lung-heat.
Herba Patriniae: suffering, hardship is slightly cold, and returns stomach, large intestine, Liver Channel has heat-clearing and toxic substances removing, the eliminating carbuncle evacuation of pus, the function of removing blood stasis is used for abdominalgia with intestinal abscess, the lung abscess sore.
Radix Saposhnikoviae: acrid in the mouth, sweet, warm in nature, bladder, liver, spleen channel has inducing diaphoresis to dispel wind, and the function of removing damp to relieve itching is used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature, go into bladder, kidney channel has the cold expelling of inducing sweat, and the function of removing damp and stopping pain is used for headache due to common cold, and rheumatism numbness is logical, aching pain in should and back.
Radix Angelicae Pubescentis: acrid in the mouth, hardship.Cold nature is gone into kidney, and urinary bladder channel has expelling wind and removing dampness, and the function of numbness relieving and pain relieving is used for cold-damp numbness pain in the lumbar region pain;
Radix Achyranthis Bidentatae: bitter in the mouth, sweet, acid, flat, return liver, kidney channel, promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, priming is descending.
The silver Caulis Lonicerae: sweet in the mouth, cold in nature, GUIXIN, lung meridian has heat-clearing and toxic substances removing, and the function of dispelling wind collateral dredging is used for the damp disease heating, toxic-heat and blood stasis, carbuncle sore tumefacting virus, bones and muscles pain.
Ramulus Mori: mildly bitter flavor, property is flat, returns Liver Channel, has expelling wind and removing dampness, and the function in sharp joint is used to take on the shoulder joint numbness of aching.
Pheretima: salty in the mouth, cold in nature, return liver, spleen, urinary bladder channel has the heat clearing away arresting convulsion, and collateral dredging is relievingd asthma, and the diuretic function is used for unconsciousness due to high fever, frightened chronic tic, joint splenalgia, numb limbs and tense tendons, hemiplegia, lung-heat edema.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature, return liver, spleen channel has invigorating blood circulation,, promoting the circulation of QI analgesic function is used for breast side of body epigastric pain, amenorrhea dysmenorrhea, stasis of blood resistance.
More than 17 flavor Chinese medicines at goat because of drawn by " give birth in damp and hot, the turbid poison, diseases caused by retention of fluid is stagnated ", and the therapeutic scheme of formulating is a kind of Chinese medicine composition based on heat clearing and damp drying, detoxifcation diuretic, easing joint movement.
The preparation method of Chinese medicine composition is as follows:
Preparation method 1
In the above-mentioned Chinese medicine composition 17 flavor Chinese crude drug is joined part by weight to be weighed up and puts into medicinal cupping, adding five jorum water loggings bubble was fried boiling with vigorous fire after two hours, using slow fire instead fried in shallow oil slowly to 30 minutes, leach medicinal liquid, its medicine adds two jorum water again and is fried boiling with vigorous fire in jar, use slow fire instead and fry in shallow oil slowly to 20 minutes, leaches medicinal liquid, remove medicinal residues, obey a prescription every day.
Preparation method 2
17 flavor Chinese crude drugs of above-mentioned Chinese medicine composition prescription are joined part by weight go into to add in the extraction pot 8 times of 70% ethanol extraction, extract each 1 hour altogether 2 times, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, and drying under reduced pressure is to 60 degree Celsius, one 0.08Mpa, promptly get extract,, add proper honey the pure one-tenth of extract powder fine powder, evenly mixed, and make honeyed pill such as WUZI size, and three times on the one, each 30.
Preparation method 3
Become fine powder according to pure 100 mesh sieves of crossing of preparation method 2 extract obtained powder, add the lactose 100 of joining part by weight, evenly mixed, drying incapsulates through sterilization, and three times on the one, each 6.
The specific embodiment
Embodiment 1:
The invention belongs to a kind of Chinese medicine composition and preparation method, the Chinese medicine of being joined part by following weight is that the drug regimen of raw material is: Cortex Phellodendri 13--18, Radix Stephaniae Tetrandrae 23--28, Semen Coicis 13--20, Herba Lysimachiae 13--20, Fructus Forsythiae 15--23, Herba Violae 15--25, Flos Lonicerae 18--25, Herba Hedyotidis Diffusae 18--25, Herba Patriniae 18--23, Radix Saposhnikoviae 23--28, Rhizoma Et Radix Notopterygii 18--30, Radix Angelicae Pubescentis 18--30, Radix Achyranthis Bidentatae 18--30, Caulis Lonicerae 18--30, Ramulus Mori 18--30, Pheretima 8--12, Rhizoma Corydalis 25--32.
Above-mentioned 17 flavor Chinese medicines were gone into jar adding five jorum water loggings bubble 2 hours, be fried boiling, use slow fire instead and fry in shallow oil slowly to 30 minutes with vigorous fire; Leach medicinal liquid, its medicine adds two jorum water again and is fried boiling with vigorous fire in jar, uses slow fire instead and fries in shallow oil slowly to 30 minutes and leach medicinal liquid, removes medicinal residues, twice medicinal liquid is mixed the back divide and take for three times.
Embodiment 2:
The invention belongs to a kind of Chinese medicine composition and preparation method, the Chinese medicine of being joined part by following weight is that the drug regimen of raw material is: Cortex Phellodendri 13--18, Radix Stephaniae Tetrandrae 23--28, Semen Coicis 13--20, Herba Lysimachiae 13--20, Fructus Forsythiae 15--23, Herba Violae 15--25, Flos Lonicerae 18--25, Herba Hedyotidis Diffusae 18--25, Herba Patriniae 18--23, Radix Saposhnikoviae 23--28, Rhizoma Et Radix Notopterygii 18--30, Radix Angelicae Pubescentis 18--30, Radix Achyranthis Bidentatae 18--30, Caulis Lonicerae 18--30, Ramulus Mori 18--30, Pheretima 8--12, Rhizoma Corydalis 25--32.
Its preparation method is as follows: with above-mentioned 17 flavor Chinese medicines.Join part by weight and go into to add in the extraction pot 8 times of 70% ethanol extraction, extract each 1 hour altogether 2 times, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, and drying under reduced pressure is to 60 degree Celsius, one 0.08Mpa, promptly get extract,, add proper honey the pure one-tenth of extract powder fine powder, evenly mixed, and make honeyed pill such as WUZI size, three times on the one, obey 30 at every turn.
Embodiment 3:
The invention belongs to a kind of Chinese medicine composition and preparation method, the Chinese medicine of being joined part by following weight is that the drug regimen of raw material is: Cortex Phellodendri 13--18, Radix Stephaniae Tetrandrae 23--28, Semen Coicis 13--20, Herba Lysimachiae 13--20, Fructus Forsythiae 15--23, Herba Violae 15--25, Flos Lonicerae 18--25, Herba Hedyotidis Diffusae 18--25, Herba Patriniae 18--23, Radix Saposhnikoviae 23--28, Rhizoma Et Radix Notopterygii 18--30, Radix Angelicae Pubescentis 18--30, Radix Achyranthis Bidentatae 18--30, Caulis Lonicerae 18--30, Ramulus Mori 18--30, Pheretima 8--12, Rhizoma Corydalis 25--32.
Its preparation method is as follows: become fine powder according to pure 100 mesh sieves of crossing of embodiment 2 extract obtained powder, join a part adding lactose 100 by weight, evenly mixed, drying incapsulates through sterilization, three times on the one, obeys 6 at every turn.
Clinical case 1, Liu, man, 59 years old, willow people from city suffered from the treatment goat 20 years, beginning right crus of diaphragm tarsometatarsal joint congestion and swelling pain, sudden swollen burning pain appears in continuous back two foots, and it is stiff to lie in bed, seek medical advice and alleviate when domestic various big hospital is controlled, drug withdrawal promptly shows effect, again and again, in January, 2007, examined, surplus with the present invention's Chinese medicine composition of goat " treatment " administration after ten days symptom alleviate to some extent, transference cure after two months does not have recurrence so far.
Clinical case 2, Dong, woman, 48 years old, the Hongqiao people suffered from goat 5 years, and it is invalid to seek medical advice in many ways, repeatedly outbreak, in May, 2008, use the present invention's " Chinese medicine composition of treatment goat " administration after ten days symptom alleviate to some extent, transference cure after two months does not have recurrence so far.

Claims (6)

1. a Chinese medicine composition and preparation method that is used for the treatment of goat, it is characterized in that: the Chinese medicine of being joined part by following weight is that the Chinese medicine composition of raw material is: Cortex Phellodendri 10--25, Radix Stephaniae Tetrandrae 15--30, Semen Coicis 10--30, Herba Lysimachiae 10--30, Fructus Forsythiae 10--25, Herba Violae 15--30, Flos Lonicerae 15--30, Herba Hedyotidis Diffusae 15--30, Herba Patriniae 15--30, Radix Saposhnikoviae 20--30, Rhizoma Et Radix Notopterygii 15--30, Radix Angelicae Pubescentis 15--30, Radix Achyranthis Bidentatae 20--30, Caulis Lonicerae 20-30, Ramulus Mori 20--30, Pheretima 5--15, Rhizoma Corydalis 20--35.
2. a kind of Chinese medicine composition and preparation method that is used for the treatment of goat according to claim 1, it is characterized in that: the Chinese medicine of being joined part by following weight is that the Chinese medicine composition of raw material is: Cortex Phellodendri 13--18, Radix Stephaniae Tetrandrae 23--28, Semen Coicis 13--20, Herba Lysimachiae 13--20, Fructus Forsythiae 15--23, Herba Violae 15--25, Flos Lonicerae 18--25, Herba Hedyotidis Diffusae 18--25, Herba Patriniae 18--23, Radix Saposhnikoviae 23--28, Rhizoma Et Radix Notopterygii 18--30, Radix Angelicae Pubescentis 18--30, Radix Achyranthis Bidentatae 18--30, Caulis Lonicerae 18--30, Ramulus Mori 18--30, Pheretima 8--12, Rhizoma Corydalis 25--32.
3. a kind of Chinese medicine composition and preparation method that is used for the treatment of goat according to claim 1 is characterized in that: the Chinese medicine of being joined part by following weight is that the Chinese medicine composition of raw material is: Cortex Phellodendri 15, Radix Stephaniae Tetrandrae 15, Semen Coicis 15, Herba Lysimachiae 15, Fructus Forsythiae 20, Herba Violae 20, Flos Lonicerae 20, Herba Hedyotidis Diffusae 20, Herba Patriniae 20, Radix Saposhnikoviae 25, Rhizoma Et Radix Notopterygii 25, Radix Angelicae Pubescentis 25, Radix Achyranthis Bidentatae 25, Caulis Lonicerae 25, Ramulus Mori 25, Pheretima 10, Rhizoma Corydalis 30.
4. a kind of Chinese medicine composition and preparation method that is used for the treatment of goat according to claim 1, it is characterized in that: described preparation method is as follows: above-mentioned 17 flavor Chinese medicines were gone into jar adding five jorum water loggings bubble 2 hours, be fried boiling with vigorous fire, use slow fire instead and fry in shallow oil slowly to 30 minutes; Leach medicinal liquid, its medicine adds two jorum water again and is fried boiling with vigorous fire in jar, uses slow fire instead and fries in shallow oil slowly to 30 minutes and leach medicinal liquid, removes medicinal residues, twice medicinal liquid is mixed the back divide and take for three times.
5. a kind of Chinese medicine composition and preparation method that is used for the treatment of goat according to claim 1, it is characterized in that: described preparation method is as follows: above medicine is joined part by weight and is gone into to add in the extraction pot 8 times of 70% ethanol extraction, extract altogether 2 times, each 1 hour, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, drying under reduced pressure is to 60 degree Celsius, and a 0.08Mpa promptly gets extract, after the drying extract powder essence is become fine powder, add proper honey, evenly mixed, and make honeyed pill such as WUZI size, three times on the one, each 30.
6. according to claim 1,5 described a kind of Chinese medicine composition and preparation methoies that are used for the treatment of goat, it is characterized in that: described preparation method is as follows: become fine powder according to pure 100 mesh sieves of crossing of the extract obtained drying powder of claim 5, add and join part lactose 100 by weight, evenly mixed, incapsulate through sterilization, three times on the one, each 6.
CN201010118768A 2010-01-31 2010-01-31 Chinese medicinal composition for treating gout disease and preparation method thereof Pending CN101745047A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912576A (en) * 2010-08-03 2010-12-15 彭树林 Medicament for treating gout and preparation process
CN103989992A (en) * 2014-05-15 2014-08-20 韦江南 Traditional Chinese medicine for treating gout
CN105012607A (en) * 2015-07-23 2015-11-04 梁峰 Gout treatment traditional Chinese medicine formula and preparation method thereof
CN107412458A (en) * 2017-05-18 2017-12-01 吉林大学 A kind of Chinese medicine preparation for treating gout
CN110123977A (en) * 2019-06-06 2019-08-16 韦玮 A kind of external application for curing diabetes merge the Chinese medicine composition of gout

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912576A (en) * 2010-08-03 2010-12-15 彭树林 Medicament for treating gout and preparation process
CN101912576B (en) * 2010-08-03 2012-11-21 彭树林 Medicament for treating gout and preparation process
CN103989992A (en) * 2014-05-15 2014-08-20 韦江南 Traditional Chinese medicine for treating gout
CN105012607A (en) * 2015-07-23 2015-11-04 梁峰 Gout treatment traditional Chinese medicine formula and preparation method thereof
CN107412458A (en) * 2017-05-18 2017-12-01 吉林大学 A kind of Chinese medicine preparation for treating gout
CN110123977A (en) * 2019-06-06 2019-08-16 韦玮 A kind of external application for curing diabetes merge the Chinese medicine composition of gout
CN110123977B (en) * 2019-06-06 2021-09-24 韦玮 Traditional Chinese medicine composition for treating diabetes combined with gout by external application

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