CN102008698A - Traditional Chinese medicine composition and preparation for curing dysmenorrhea - Google Patents

Traditional Chinese medicine composition and preparation for curing dysmenorrhea Download PDF

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Publication number
CN102008698A
CN102008698A CN 201010576642 CN201010576642A CN102008698A CN 102008698 A CN102008698 A CN 102008698A CN 201010576642 CN201010576642 CN 201010576642 CN 201010576642 A CN201010576642 A CN 201010576642A CN 102008698 A CN102008698 A CN 102008698A
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chinese medicine
medicine composition
dysmenorrhea
treatment
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贾孝荣
王新本
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贾孝荣
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Abstract

The invention provides a traditional Chinese medicine composition and preparation for curing dysmenorrheal, belonging to the field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared through the following steps: mixing Cloves, cortex cinnamomi, cassia twig, rhizoma zingiberis, asarum and fructus evodiae in a certain proportion; and respectively preparing the mixture into electuary, fluidextract, extract, vinum, tincture, pulvis and other externally applied preparations according to auxiliary materials and processes which are commonly used in the science of Chinese traditional medicine. Clinical trials prove that the composition has good curative effective on dysmenorrheal for women, has certain alleviation and health-care effects on rheumatic arthritis, scapulohumeral periarthritis, inflammatory vertebra and other osteoarthritis simultaneously, has certain recovery and health-care effect on patients suffering from constipations and haemorrhoids, has certain health-care effect on deficiency-cold gastrointestinal tract diseases, has certain health-care effect on male and female sexual debility, has favorable recovery and health-care effect on patients suffering from sensation of chill and ice-cold limbs and has obvious alleviation and health-care effect on female gynecological inflammation, skin-appearance premature aging syndrome and other diseases.

Description

A kind of Chinese medicine composition and preparation thereof for the treatment of dysmenorrhea
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition that is used for the treatment of dysmenorrhea.The externally applied formulation that also relates to this Chinese medicine composition simultaneously, this externally applied formulation can adopt no moxibustion method to act on human body by skin or acupuncture point, to improve therapeutic effect.
Technical background
Dysmenorrhea is meant that the women in menstrual period and front and back thereof, lower abdomen or flank pain occur, even pain and waist sacrum.Whenever send out with menstrual cycle, severe patient can be accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and brings influence for work and life.Present clinical two kinds of constitutional and the Secondary cases that often it are divided into, primary dysmenorrhea refers to that the genitals does not have obvious pathological changes person more, so claim primary dysmenorrhea again, is more common in adolescent girls, the unmarried and married person of not educating.Many can the alleviation or disappear of this kind dysmenorrhea pain after normal labor.Secondary dysmenorrhea is then many to be had due to the organic disease because of the genitals.Primary disease belongs to the commonly encountered diseases of gynecological clinic, shows according to relevant investigation, and the sickness rate of dysmenorrhea is 33.19%.The medicine of treatment dysmenorrhea is a lot of at present, but all is oral preparations basically.
Moxibustion is a Chinese medicine with moxibustion grass wick or the moxibustion swath burns on the certain acupuncture point of body surface, a kind of therapy of the smoked preventing and treating diseases of pressing.Promoting the flow of QI-blood by warming the meridian, QI and blood regulating, a surname manage the exterior and the interior, the disease preventing and treating of building up resistance thereby moxibustion has.The common feature of traditional moxibustion: based on Folium Artemisiae Argyi; Folk prescription moxa-moxibustion and thunder moxibustion are arranged, all have fire that cigarette is arranged; Contact skin or acupuncture point.
The moxibustion principle: human body is the organic whole of a unity of opposites, between about its vital organs of the human body, extremity bones of the body collectively, the exterior and the interior, all passing through meridians, QI and blood links to each other, the physiological activity and the pathological change of all histoorgans in the body, must be reflected to a certain position of body surface, so moxibustion is exactly to reflect that to skin point or acupuncture point are to stimulate, to reach the purpose of preventing and curing diseases with methods such as moxibustion, acupunctures.From the modern medicine viewpoint, the moxibustion acupuncture point can be understood as the reflection of the activity of a fixed structure in the body at the body surface corresponding site, the body inner structure comprises internal organs and all histoorgans, muscle, bone road and links their nerve, blood vessel, lymph etc., to reach the purpose of treatment.
Before this by traditional moxibustion treat, the technology and the method for health care, body shaping, beauty treatment be a lot, yet following problem is mostly arranged: 1) prescription is complicated, is difficult to be converted into product; 2) implement comparatively complicatedly, have cigarette that fire is arranged again, contaminated environment needs the special messenger to instruct or operates, so be not easy to popularization.
Smokeless moxibustion is the novel therapies that occurs in recent years, and smokeless moxibustion bar is made up of Rhizoma Et Radix Notopterygii, Herba Asari, the Radix Angelicae Dahuricae, Radix Et Rhizoma Nardostachyos, the Radix Aucklandiae, charred Folium Artemisiae Argyi usually.Earlier charred Folium Artemisiae Argyi is ground into fine powder, ground spices such as all the other Rhizoma Et Radix Notopterygiis are broken into fine powder, sieve mixing.Other gets Resina persicae fine powder (medicinal) 250g, adds in the proper amount of boiling water, makes rubber cement, after getting starch (medicinal) 750g again and adding the suitable quantity of water moistening, adds in the rubber cement, stirs into translucent pasty state, puts cold.Above-mentioned two kinds of fine powders are put in the blender, and mixing adds above-mentioned Resina persicae, starch mixing slurry, fully stirs evenly, and makes soft material, makes medicated strip with moxibustion bar machine, oven dry, promptly.This product is the cylindrical bar that is about 12cm, the about 1.3cm of diameter, and the surface shows lark, glossy or surface black; That about 2cm of head is black, section black; Omit tool fragrance.The cigarette that minute quantity is arranged after lighting, however just because of,, lose the essence of moxibustion basically so therapeutic effect is had a greatly reduced quality in advance with the Folium Artemisiae Argyi carbonization.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of dysmenorrhea.
Another object of the present invention provides the externally applied formulation of this Chinese medicine composition.
The present invention is used for the treatment of the Chinese medicine composition of dysmenorrhea, selects Flos Caryophylli, Cortex Cinnamomi, Ramulus Cinnamomi, Rhizoma Zingiberis, Herba Asari, Fructus Evodiae Six-element to make up.Wherein, Flos Caryophylli, warm in nature, acrid in the mouth; Go into lung, spleen, stomach, kidney four warps; Effect with warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI; Cure mainly singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.Cortex Cinnamomi, extremely hot in nature, acrid in the mouth, sweet; Return kidney, spleen, the heart, Liver Channel; It is supporing yang to have the fire of benefit, let the fire back to its origin, dispersing cold for relieving pain, the effect of promoting blood circulation to restore menstrual flow; Be mainly used in sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation.Ramulus Cinnamomi, warm in nature, sweet in the mouth, suffering; GUIXIN, lung, urinary bladder channel (diaphoresis power is weak); Has the diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, the effect of dispersing cold for relieving pain.Rhizoma Zingiberis, acrid in the mouth, hot in nature; Return spleen, stomach, the heart, lung meridian; Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, the effect of warming the lung to resolve fluid-retention.Herba Asari is returned lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel; The tool cold expelling dispels the wind, pain relieving, the sensible effect of warming the lung to resolve fluid-retention; Cure mainly exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia, phlegm retention cough with asthma, nasal obstruction, nasal sinusitis, aphtha etc.Fructus Evodiae, hot in nature, acrid in the mouth, hardship; The effect of tool dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal; Be used to have a headache, the treatment of colic, beriberi, dysmenorrhea, abdominal distention, vomiting acid regurgitation, aphtha etc.The present invention makes up above-mentioned Six-element, makes the effect of each component drug produce synergism, by warming the spleen be good for the stomach, warming the kidney to activate YANG; Mend fiery cold expelling, warming the meridian and promoting blood circulation; Warm limbs, easing joint movement; Harmonizing yingfen and weifen, benefiting QI for activating blood circulation; Catharsis and toxin expelling, damp eliminating dissipating blood stasis; Warming YANG stopping leak, circulation of qi promoting help the mechanism of face, to reach the effect of treatment dysmenorrhea.
The concrete prescription of medicine of the present invention is as follows: in weight portion
10-90 parts of 10-90 parts of Ramulus Cinnamomi of 10-90 parts of Cortex Cinnamomis of Flos Caryophylli
10-90 parts of 5-15 parts of Fructus Evodiaes of 10-90 parts of Herba Asaris of Rhizoma Zingiberis.
Optimum ratio is as follows:
30-60 parts of 30-60 parts of Ramulus Cinnamomi of 30-60 parts of Cortex Cinnamomis of Flos Caryophylli
30-60 parts of 5-10 parts of Fructus Evodiaes of 30-60 parts of Herba Asaris of Rhizoma Zingiberis.
Medicine of the present invention can adopt technology and adjuvant conventional on the Chinese materia medica to be prepared into externally used paste, as soft extract, fluid extract, extractum etc.In order to strengthen the dermal osmosis ability of medicine, can also add the short skin penetrating agent (as azone) of its total amount 0.5 ~ 1.5% and an amount of antiseptic, spice etc.
Medicine of the present invention also can adopt common process and the adjuvant of producing medicated wine or tincture on the Chinese materia medica to be prepared into medicated wine or tincture.
Medicine of the present invention directly grinds to form powder after also each component can being mixed.
Each component that can also pharmaceutical composition of the present invention is an active component, adopts common process and the adjuvant of producing cosmetics to be prepared into essence or cream frost.
The using method of soft extract, fluid extract, extractum: cleaning skin during use, get and be coated on acupuncture point or umbilicus in right amount, and, treat that local pyrexia discards preservative film and unguentum in the time of extremely can not tolerating with preservative film covering and fixing, every day or the next day once, 30 days is a course of treatment.
The using method of cream frost: cleaning skin during use, get an amount of this product and be applied to acupuncture point or umbilicus, and cover and fixing with preservative film, treat that local pyrexia discards preservative film and cream frost to can not tolerate the time, every day or the next day once, 30 days is a course of treatment.
The using method of powder: with this product with the modulation of an amount of vinegar or drinking white spirit after, spread on acupuncture point or umbilicus, and cover fixingly with preservative film, treat that local pyrexia discards preservative film and unguentum to can not tolerate the time, every day or the next day once, 30 days is a course of treatment.
The using method of essence, medicated wine, tincture: cleaning skin during use, get an amount of this product and be applied to acupuncture point or umbilicus, and cover and fixing with preservative film, treat that local pyrexia discards preservative film to can not tolerate the time, every day or the next day once, 30 days is a course of treatment.
Be the clinical trial data of traditional Chinese medicine composition for treating woman's dysmenorrhea of the present invention below.
The object of observation: all gynecologic menstruals or the front and back of passing through, hypogastric region distending pain, cold type of pain, causalgia, twinge, dull pain, bob pain, angor, spasmic pain, tearing property pain periodically take place, pain spreads to the sacrum lower back, even relate to thigh and foot, often with General Symptoms have that distending pain of the breast, rectal tenesmus, agitation uncomfortable in chest, sad irritability, the frightened insomnia of the heart, headache and dizzy, nausea and vomiting, stomachache diarrhoea, fatigue and weakness, pale complexion, extremity are ice-cold, dripping cold sweat, collapse faintness person.Totally 498 examples, the age, the mean age was 27 years old between 9-45 years old.
Curative effect is judged: 30 days is a course of treatment.Treated for 3 courses of treatment altogether.Pain stops and General Symptoms complete obiteration and be recovery from illness with examining in March not repeatedly the person fully; Pain stops fully but person or alleviate three/the two is produce effects repeatedly after March; Pain etc. alleviate 1/3rds for effective; The no change person is invalid in 3 courses of treatment.
Therapeutic Method: brought into use through preceding 7 days, 1-3 of essences of the present invention (about 1ml) are dripped in umbilicus, treat that natural drying gets final product; Get this product 1-2ml again and drip in Guanyuan acupoint and painful area, smear evenly, back to be dried covers with preservative film and is fixing, locally warmingly treats that local pyrexia discards preservative film to can not tolerate the time and gets final product, and once a day, per 30 days is a course of treatment.
Observed result: 433 examples of fully recovering, account for 87%, produce effects 25 examples, account for 5%, effective 17 examples, account for 3.4%, invalid 23 examples, account for 4.6%, total effective rate is 95.4%.
Clinical research finds that medicine of the present invention also has following function except effectively treating the dysmenorrhes:
1, osteoarthritis such as rheumatic arthritis, scapulohumeral periarthritis, scorching post there is certain alleviation health-care effect;
2, constipation and hemorrhoid patients there is certain rehabilitation effect;
3, asthenic cold type gastrointestinal tract illness there is certain health-care effect;
4, men and women's sexual disorder there is certain health-care effect;
5, to being afraid of cold and the cold limbs patient has good rehabilitation effect;
6, women's gynecological inflammation and skin appearance senilism syndrome etc. had tangible alleviation health-care effect.
The specific embodiment
Embodiment 1: the preparation of soft extract
Prescription: in weight portion
30 parts of 30 parts of Ramulus Cinnamomi of 60 portions of Cortex Cinnamomis of Flos Caryophylli
30 parts of 5 parts of Fructus Evodiaes of 30 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: press the formula optimization medical material, screening is cleaned, and with deionized water extraction twice, discards medicinal residues, retains medicinal liquid and concentrated extract to 25%-50%, adds short skin penetrating agent of 0.5%-1.5% azone and an amount of antiseptic, spice again, and degerming, packing get final product.
The preparation of embodiment 2, fluid extract
Prescription: in weight portion
40 parts of 30 parts of Ramulus Cinnamomi of 50 portions of Cortex Cinnamomis of Flos Caryophylli
40 parts of 10 parts of Fructus Evodiaes of 30 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: by above-mentioned formula optimization medical material, screening is cleaned, and is prepared into fluid extract according to common process and the adjuvant of producing fluid extract on the Chinese materia medica, adds short skin penetrating agent of 0.5%-1.5% azone and an amount of antiseptic, spice again, and degerming, packing get final product.
The preparation of embodiment 3, extractum
Prescription: in weight portion
40 parts of 40 parts of Ramulus Cinnamomi of 40 portions of Cortex Cinnamomis of Flos Caryophylli
40 parts of 10 parts of Fructus Evodiaes of 40 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: by above-mentioned formula optimization medical material, screening is cleaned, and is prepared into extractum according to common process and the adjuvant of producing extractum on the Chinese materia medica, adds short skin penetrating agent of 0.5%-1.5% azone and an amount of antiseptic, spice again, and degerming, packing get final product.
Embodiment 4: the preparation of medicated wine
Prescription: in weight portion
40 parts of 40 parts of Ramulus Cinnamomi of 30 portions of Cortex Cinnamomis of Flos Caryophylli
30 parts of 5 parts of Fructus Evodiaes of 30 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: press the formula optimization medical material, screening is cleaned, and gets effective ingredient twice with Chinese liquor extraction, press the adjuvant commonly used and the prepared of preparation medicated wine on the Chinese materia medica again, and packing gets final product.
The preparation of embodiment 5, tincture
Prescription: in weight portion
50 parts of 60 parts of Ramulus Cinnamomi of 30 portions of Cortex Cinnamomis of Flos Caryophylli
30 parts of 10 parts of Fructus Evodiaes of 40 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: press the formula optimization medical material, the screening cleaning, the adjuvant commonly used and the technology of pressing preparation tincture on the Chinese materia medica again are prepared into tincture and packing gets final product.
Embodiment 6: the preparation of powder
Prescription: in weight portion
60 parts of 50 parts of Ramulus Cinnamomi of 30 portions of Cortex Cinnamomis of Flos Caryophylli
40 parts of 8 parts of Fructus Evodiaes of 60 parts of Herba Asaris of Rhizoma Zingiberis.
Technology: press the formula optimization medical material, directly be ground into 80-120 purpose powder after screening cleaning, the drying, packing promptly after the degerming.
The preparation of embodiment 7, essence
Prescription: in weight portion
60 parts of 30 parts of Ramulus Cinnamomi of 35 portions of Cortex Cinnamomis of Flos Caryophylli
30 parts of 10 parts of Fructus Evodiaes of 50 parts of Herba Asaris of Rhizoma Zingiberis.
Technology:, and adopt the common process of producing cosmetics to be prepared into the liquid essence with the effective ingredient of ethanol or deionized water extraction compositions.
The preparation of embodiment 8, cream frost of the present invention
Prescription: in weight portion
45 parts of 30 parts of Ramulus Cinnamomi of 55 portions of Cortex Cinnamomis of Flos Caryophylli
30 parts of 7 parts of Fructus Evodiaes of 55 parts of Herba Asaris of Rhizoma Zingiberis.
Technology:, and adopt the common process of producing cosmetics to be prepared into the cream frost with the effective ingredient of ethanol or deionized water extraction compositions.

Claims (7)

1. Chinese medicine composition that is used for the treatment of dysmenorrhea is that the feedstock production by following weight portion forms:
10-90 parts of 10-90 parts of Ramulus Cinnamomi of 10-90 parts of Cortex Cinnamomis of Flos Caryophylli
10-90 parts of 5-15 parts of Fructus Evodiaes of 10-90 parts of Herba Asaris of Rhizoma Zingiberis.
2. be used for the treatment of the Chinese medicine composition of dysmenorrhea according to claim 1, it is characterized in that: preferred weight part of described each raw material is:
30-60 parts of 30-60 parts of Ramulus Cinnamomi of 30-60 parts of Cortex Cinnamomis of Flos Caryophylli
30-60 parts of 5-10 parts of Fructus Evodiaes of 30-60 parts of Herba Asaris of Rhizoma Zingiberis.
3. be used for the treatment of the Chinese medicine composition of dysmenorrhea as claimed in claim 1 or 2, it is characterized in that: adopt technology and adjuvant conventional on the Chinese materia medica to be prepared into soft extract, fluid extract, extractum.
4. be used for the treatment of the Chinese medicine composition of dysmenorrhea as claimed in claim 1 or 2, it is characterized in that: adopt common process and the adjuvant of producing medicated wine or tincture on the Chinese materia medica to be prepared into medicated wine or tincture.
5. be used for the treatment of the Chinese medicine composition of dysmenorrhea as claimed in claim 1 or 2, it is characterized in that: directly grind to form powder after described each component is mixed.
6. be used for the treatment of the Chinese medicine composition of dysmenorrhea as claimed in claim 1 or 2, it is characterized in that: with described each component is active component, adopts common process and the adjuvant of producing cosmetics to be prepared into essence or cream frost.
7. as being used for the treatment of the Chinese medicine composition of dysmenorrhea as described in the claim 3, it is characterized in that: in described soft extract, fluid extract or the agent extractum, add the short skin penetrating agent of its total amount 0.5 ~ 1.5%.
CN 201010576642 2010-12-07 2010-12-07 Traditional Chinese medicine composition and preparation for curing dysmenorrhea Pending CN102008698A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104489663A (en) * 2014-12-10 2015-04-08 常州兆阳光能科技有限公司 Health product capable of removing body cold
CN105125691A (en) * 2015-09-29 2015-12-09 济南邦文医药科技有限公司 Traditional Chinese medicine composition for treating qi and yang deficiency type constipation after hemorrhoids PPH (Procedure for Prolapse and Hemorrhoids) surgery
CN105169171A (en) * 2015-09-29 2015-12-23 济南邦文医药科技有限公司 Traditional Chinese medicine composition for treating yin-coldness stagnation type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease
CN106236854A (en) * 2016-10-21 2016-12-21 上海市静安区芷江西路街道社区卫生服务中心 The Chinese medicine composition of a kind for the treatment of of arthritis and application thereof
CN107375604A (en) * 2017-08-08 2017-11-24 河南真寿堂医药科技有限公司 A kind of Chinese medicine, preparation method and its application method of warm the womb treatment dysmenorrhoea

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CN1814273A (en) * 2005-12-05 2006-08-09 贾孝荣 Chinese health-cave medicine acting through navel and prepartion thereof

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104489663A (en) * 2014-12-10 2015-04-08 常州兆阳光能科技有限公司 Health product capable of removing body cold
CN105125691A (en) * 2015-09-29 2015-12-09 济南邦文医药科技有限公司 Traditional Chinese medicine composition for treating qi and yang deficiency type constipation after hemorrhoids PPH (Procedure for Prolapse and Hemorrhoids) surgery
CN105169171A (en) * 2015-09-29 2015-12-23 济南邦文医药科技有限公司 Traditional Chinese medicine composition for treating yin-coldness stagnation type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease
CN106236854A (en) * 2016-10-21 2016-12-21 上海市静安区芷江西路街道社区卫生服务中心 The Chinese medicine composition of a kind for the treatment of of arthritis and application thereof
CN106236854B (en) * 2016-10-21 2020-04-17 上海市静安区芷江西路街道社区卫生服务中心 Traditional Chinese medicine composition for treating arthritis and application thereof
CN107375604A (en) * 2017-08-08 2017-11-24 河南真寿堂医药科技有限公司 A kind of Chinese medicine, preparation method and its application method of warm the womb treatment dysmenorrhoea

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Application publication date: 20110413