CN107250091B - 合成光学活性羰基化合物的方法 - Google Patents

合成光学活性羰基化合物的方法 Download PDF

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Publication number
CN107250091B
CN107250091B CN201580076501.0A CN201580076501A CN107250091B CN 107250091 B CN107250091 B CN 107250091B CN 201580076501 A CN201580076501 A CN 201580076501A CN 107250091 B CN107250091 B CN 107250091B
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alkyl
aryl
unsubstituted
hydrogen
cycloalkyl
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CN107250091A (zh
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M·施尔维斯
R·帕切洛
G·海德里希
G·威格纳
G-D·特贝恩
M·豪布纳
A·凯勒
O·贝
S·伦茨
G·希贝尔
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BASF SE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C07C29/172—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with the obtention of a fully saturated alcohol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/56—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by isomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201580076501.0A 2014-12-19 2015-12-18 合成光学活性羰基化合物的方法 Active CN107250091B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14199410 2014-12-19
EP14199410.3 2014-12-19
PCT/EP2015/080392 WO2016097242A1 (de) 2014-12-19 2015-12-18 Verfahren zur herstellung optisch aktiver carbonylverbindungen

Publications (2)

Publication Number Publication Date
CN107250091A CN107250091A (zh) 2017-10-13
CN107250091B true CN107250091B (zh) 2021-05-04

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CN201580076501.0A Active CN107250091B (zh) 2014-12-19 2015-12-18 合成光学活性羰基化合物的方法

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US (3) US9975837B2 (enExample)
EP (2) EP3489213B1 (enExample)
JP (1) JP6702974B2 (enExample)
CN (1) CN107250091B (enExample)
ES (2) ES2727384T3 (enExample)
MX (1) MX375969B (enExample)
WO (1) WO2016097242A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107735392B (zh) 2015-05-04 2021-12-03 巴斯夫欧洲公司 制备甜瓜醛的方法
ES2835060T3 (es) 2015-10-12 2021-06-21 Basf Se Procedimiento de hidroformilación para preparar derivados de hexano 1,6-disustituidos
ES2899827T3 (es) 2015-12-08 2022-03-14 Basf Se Material zeolítico que contiene estaño y que tiene una estructura de marco BEA
ES2844182T3 (es) 2016-06-07 2021-07-21 Basf Se Procedimiento para la preparación de alcoholes con insaturación en posición 2,3
MY191494A (en) 2016-06-29 2022-06-28 Basf Se Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase
ES2857957T3 (es) 2016-10-06 2021-09-29 Basf Se Procedimiento de enriquecimiento de enantiómeros a partir de una mezcla de enantiómeros
WO2019121012A1 (en) * 2017-12-21 2019-06-27 Basf Se Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase
EP3847151B1 (de) * 2018-09-05 2022-11-09 Basf Se Kontinuierliche herstellung einer optisch aktiven carbonylverbindung durch asymmetrische hydrierung
CN112770834B (zh) * 2018-09-05 2023-07-21 巴斯夫欧洲公司 进行气/液两相高压反应的方法
ES2933963T3 (es) 2018-09-05 2023-02-15 Basf Se Reactor para llevar a cabo una reacción entre dos fluidos inmiscibles de diferentes densidades
ES2934908T3 (es) 2018-09-05 2023-02-27 Basf Se Reactor para llevar a cabo una reacción bifásica de gas/líquido de alta presión con un medio espumante
US20220242807A1 (en) * 2019-05-27 2022-08-04 Dsm Ip Assets B.V. Selective hydrogenation of alkynes to alkenes in the presence of a phosphorus compound and an organic sulphur compound
CN111056932A (zh) * 2019-12-09 2020-04-24 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法
WO2021114021A1 (zh) 2019-12-09 2021-06-17 万华化学集团股份有限公司 一种光学活性的香茅醛的制备方法
CN110872217A (zh) * 2019-12-09 2020-03-10 万华化学集团股份有限公司 一种光学活性的香茅醛的制备方法
CN111004102B (zh) * 2019-12-23 2022-11-04 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂
CN111056933B (zh) * 2019-12-24 2022-11-08 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂体系
CN111792986B (zh) * 2020-07-22 2022-09-20 万华化学集团股份有限公司 一种制备r-香茅醛的方法
CN112142583B (zh) * 2020-10-26 2022-07-26 万华化学集团股份有限公司 一种香叶醛制备橙花醛的方法
CN113527367B (zh) * 2021-07-14 2022-08-02 南开沧州渤海新区绿色化工研究有限公司 一种含四（3,5-二三氟甲基苯基）硼阴离子的手性双膦配体铑络合物和制备方法及应用
WO2025011972A1 (en) 2023-07-07 2025-01-16 Basf Se Photoisomerization of geranial and neral

Citations (4)

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US4237072A (en) * 1977-07-04 1980-12-02 Rhone-Poulenc Industries Preparation of optically active citronellal
CN101065344A (zh) * 2004-11-26 2007-10-31 巴斯福股份公司 薄荷醇的制备方法
CN101675020A (zh) * 2007-04-25 2010-03-17 巴斯夫欧洲公司 合成光学活性羰基化合物的方法
EP2543437A2 (en) * 2010-03-04 2013-01-09 Takasago International Corporation Homogeneous asymmetric hydrogenation catalyst

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US4123465A (en) * 1975-10-16 1978-10-31 Hoffmann-La Roche Inc. Chiral tertiary phosphines
JPS5278812A (en) 1975-12-26 1977-07-02 Nikki Chem Co Ltd Selective production method of saturated aldehyde
DE19854637A1 (de) 1998-11-26 2000-05-31 Basf Ag Reaktor zur kontinuierlichen Durchführung von Gas-Flüssig-, Flüssig-Flüssig- oder Gas-Flüssig-Fest-Reaktionen
JP4676617B2 (ja) 2001-01-18 2011-04-27 高砂香料工業株式会社 イソプレゴールの製造方法
DE102004049631A1 (de) * 2004-10-11 2006-04-20 Basf Ag Verfahren zur Herstellung optisch aktiver Carbonylverbindungen
AR070176A1 (es) * 2008-01-17 2010-03-17 Novartis Ag Procesos de sintesis de inhibidores de nep, compuestos intermediarios y uso de los mismos en la sintesis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237072A (en) * 1977-07-04 1980-12-02 Rhone-Poulenc Industries Preparation of optically active citronellal
CN101065344A (zh) * 2004-11-26 2007-10-31 巴斯福股份公司 薄荷醇的制备方法
CN101675020A (zh) * 2007-04-25 2010-03-17 巴斯夫欧洲公司 合成光学活性羰基化合物的方法
EP2543437A2 (en) * 2010-03-04 2013-01-09 Takasago International Corporation Homogeneous asymmetric hydrogenation catalyst

Non-Patent Citations (3)

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Title
"Achiral Ligands Dramatically Enhance Rate and Enantioselectivity in the Rh/Phosphoramidite-Catalyzed Hydrogenation of α,β-Disubstituted Unsaturated Acids";Rob Hoen , Jeroen A. F 等;《Angew. Chem. Int. Ed》;20050623;第44卷;摘要、表1-2 *
"Carbonylhydridotris(triphenyl-phosphine)rhodium(I)";Maree P. Collis & Patrick Perlmutter;《Encyclopedia of Reagents for Organic Synthesis》;20071231;全文 *
"Highly Enantio- and s-trans C=C Bond Selective Catalytic Hydrogenation of Cyclic Enones: Alternative Synthesis of (-)-Menthol";Takashi Ohshima 等;《Chem. Eur. J》;20081231;第14卷;表1 *

Also Published As

Publication number Publication date
JP2017537965A (ja) 2017-12-21
EP3489213A1 (de) 2019-05-29
US10301244B2 (en) 2019-05-28
MX2017008170A (es) 2017-09-18
EP3489213B1 (de) 2021-04-28
US20180244598A1 (en) 2018-08-30
CN107250091A (zh) 2017-10-13
EP3233778B1 (de) 2019-02-20
MX375969B (es) 2025-03-06
USRE49036E1 (en) 2022-04-19
US20180057437A1 (en) 2018-03-01
WO2016097242A1 (de) 2016-06-23
JP6702974B2 (ja) 2020-06-03
EP3233778A1 (de) 2017-10-25
US9975837B2 (en) 2018-05-22
ES2883557T3 (es) 2021-12-09
ES2727384T3 (es) 2019-10-15

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