CN107208068A - 新型产志贺毒素F18型大肠杆菌噬菌体Esc‑COP‑1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途 - Google Patents

新型产志贺毒素F18型大肠杆菌噬菌体Esc‑COP‑1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途 Download PDF

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CN107208068A
CN107208068A CN201580071183.9A CN201580071183A CN107208068A CN 107208068 A CN107208068 A CN 107208068A CN 201580071183 A CN201580071183 A CN 201580071183A CN 107208068 A CN107208068 A CN 107208068A
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尹成俊
姜尚铉
全秀娟
白亨琭
孙志洙
朴硕晃
金炳局
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Abstract

本发明涉及从自然界分离的并可以特异性地杀死产志贺毒素F18型大肠杆菌菌株的肌尾噬菌体科噬菌体Esc‑COP‑1,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12662BP),以及使用包含所述噬菌体作为活性成分的组合物来预防和治疗产志贺毒素F18型大肠杆菌感染的方法。

Description

新型产志贺毒素F18型大肠杆菌噬菌体Esc-COP-1及其用于抑 制产志贺毒素F18型大肠杆菌增殖的用途
技术领域
本发明涉及一种从自然界分离的感染和杀死产志贺毒素F18型大肠杆菌的噬菌体,以及一种使用包含噬菌体作为活性成分的组合物用来预防和治疗产志贺毒素F18型大肠杆菌感染的方法。更具体地说,本发明涉及从自然界分离出来的并可以特异性地杀死产志贺毒素F18型大肠杆菌菌株的肌尾噬菌体科噬菌体Esc-COP-1,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12662BP)以及预防产志贺毒素F18型大肠杆菌感染和之后使用包含所述噬菌体作为活性成分的组合物治疗的方法。
背景技术
有两种大肠杆菌(E.coli):非致病性大肠杆菌和致病性大肠杆菌。非致病性大肠杆菌是肠道中的正常固有菌群,有利于与其他肠细菌平衡,有助于消化等。致病性大肠杆菌通过菌毛附着在肠壁上增殖并产生引起腹泻的肠毒素。
致病性大肠杆菌影响各种不同年龄的家畜,引起明显的症状-腹泻,其可能由于脱水导致高死亡率。在韩国,据报道,这种腹泻几乎在大部分家畜养殖场发生。此外,在轮状病毒、冠状病毒、原生球虫等的混合感染的情况下,与单一感染的情况相比,这种发作是因为损伤肠粘膜而引起的,症状高度加重。有几种致病性大肠杆菌菌株引起腹泻。尤其是,产志贺毒素F18型大肠杆菌通常被报道会在猪中引起严重的腹泻和水肿。产志贺毒素F18型大肠杆菌通过菌毛(F18)附着在肠上皮细胞上,以分泌志贺毒素。分泌的毒素被吸收到血管中增加血压并损伤小动脉,从而在身体的各个部分产生水肿并伴随惊厥、瘫痪等。考虑到产志贺毒素F18型大肠杆菌对畜牧业的重大损害,迫切需要开发有效预防和治疗这种感染的方法。已经使用各种抗生素来预防或治疗产志贺毒素F18型大肠杆菌的这种感染。然而,由于耐抗生素性细菌的增加,迫切需要有效的替代方法。
最近,使用噬菌体作为治疗细菌感染的新方法引起了我们的注意。特别地,我们对噬菌体非常感兴趣的原因是因为基于噬菌体的治疗是一种自然友好的方法。噬菌体是感染细菌的极小微生物,简称为噬菌体。一旦噬菌体感染细菌,噬菌体在细菌细胞内增殖。完全增殖后,后代破坏细菌细胞壁逃离宿主,这说明噬菌体具有杀菌能力。噬菌体感染的特征是特异性高,使得特定噬菌体仅感染特异性细菌。也就是说,可以被特定噬菌体感染的细菌是有限的,这表明噬菌体只能杀死特定细菌并且不会伤害其他细菌。
噬菌体首先由英国细菌学家特沃特(Twort)在1915年发现,当时他注意到微球菌菌落被未知的某种东西融化并变得透明。1917年,法国细菌学家d'Herelle发现,痢疾病人粪便的滤液中的痢疾志贺菌(Shigella disentriae)被某物融化,并进一步研究了这种现象。结果是,他独自确定了噬菌体,并将其命名为噬菌体,其意思是病菌杀手。从那时起,已经连续鉴定了特异性地作用于志贺菌(Shigella)、伤寒沙门氏菌(Salmonella Typhi)和霍乱弧菌(Vibrio cholerae)等致病菌的噬菌体。
由于噬菌体杀死细菌的独特能力,已经研究并预期噬菌体是治疗细菌感染的更好的方法。然而,Fleming发现青霉素之后,由于抗生素的普及,只有东欧国家和前苏联的噬菌体研究在继续。2000年以后,常规抗生素的优点由于耐抗生素性细菌的增加而褪色。因此,噬菌体再次被视为可以代替常规抗生素的新的抗菌剂。
此外,最近全球政府强化对使用抗生素的监管。对噬菌体感兴趣的越来越多,工业应用也越来越多。
因此,本发明人尝试通过使用从自然界中分离的可以选择性地杀死产志贺毒素F18型大肠杆菌的噬菌体而开发可用于预防或治疗产志贺毒素F18型大肠杆菌感染的组合物,并进一步建立使用该组合物预防或治疗产志贺毒素F18型大肠杆菌感染的方法。结果是,本发明人分离出适合于此目的的噬菌体,并确定了可将本发明的噬菌体与其他噬菌体区分开的基因组的核苷酸序列。然后,我们已经开发了一种包含分离的噬菌体作为活性成分的组合物,并证实该组合物可以有效地用于预防和治疗产志贺毒素F18型大肠杆菌感染,完成本发明。
发明内容
本发明的目的是提供一种从自然界中分离的并可以特异性杀死产志贺毒素F18型大肠杆菌的肌尾噬菌体科的噬菌体Esc-COP-1,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12662BP)。
本发明的另一个目的是提供一种适用于预防产志贺毒素F18型大肠杆菌感染的组合物,其包含可以感染和杀死产志贺毒素F18型大肠杆菌的噬菌体Esc-COP-1作为活性成分,以及使用所述组合物预防产志贺毒素F18型大肠杆菌感染的方法。
本发明的另一个目的是提供一种适用于治疗产志贺毒素F18型大肠杆菌感染的组合物,其包含可以感染和杀死产志贺毒素F18型大肠杆菌的噬菌体Esc-COP-1作为活性成分,以及使用所述组合物治疗产志贺毒素F18型大肠杆菌感染的方法。
本发明的另一个目的是提供一种用于使用所述组合物预防和治疗产志贺毒素F18型大肠杆菌感染的消毒剂。
本发明的另一个目的是提供一种用于使用所述组合物预防和治疗产志贺毒素F18型大肠杆菌感染的饮用水添加剂。
本发明的另一个目的是提供一种通过使用所述组合物预防和治疗产志贺毒素F18型大肠杆菌的感染而对养殖业有效的饲料添加剂。
为了实现上述目的,本发明提供了一种从自然界分离出来的并可以特异性地杀死产志贺毒素F18型大肠杆菌的肌尾噬菌体科噬菌体Esc-COP-1,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12662BP),以及使用包含噬菌体作为活性成分的组合物来预防和治疗产志贺毒素F18型大肠杆菌感染的方法。噬菌体Esc-COP-1由本发明人分离,然后于2014年8月21日保藏于韩国生物科学和生物工艺学研究院韩国典型培养物保藏中心(登记号:KCTC 12662BP)。本发明还提供一种适用于预防或治疗产志贺毒素F18型大肠杆菌感染的消毒剂、饮用水添加剂和饲料添加剂,其包含噬菌体Esc-COP-1作为活性成分。
由于本发明的组合物中包含的噬菌体Esc-COP-1有效地杀死产志贺毒素F18型大肠杆菌,因此被认为对预防或治疗由产志贺毒素F18型大肠杆菌引起的大肠杆菌腹泻(感染)是有效的。因此,本发明的组合物可用于预防和治疗由产志贺毒素F18型大肠杆菌引起的大肠杆菌腹泻。在本说明书中,大肠杆菌腹泻包括伴随发烧,腹泻等的大肠杆菌感染引起的症状。
在本说明书中,术语“治疗(treatment)”或“治疗(treat)”表示(i)抑制由产志贺毒素F18型大肠杆菌引起的腹泻;和(ii)缓解由产志贺毒素F18型大肠杆菌引起的腹泻。
在本说明书中,术语“分离(isolation)”或“分离的(isolated)”表示通过使用不同的实验技术分离噬菌体的所有操作,和确保能够区分该噬菌体与其他噬菌体的特征的操作,还包括通过生物工程技术增殖噬菌体使其有用的操作。
包含在本发明组合物中的药学上可接受的载体是通常用于制备药物制剂的药物载体,其实例为乳糖、葡萄糖、蔗糖、山梨糖醇、甘露醇、淀粉、阿拉伯树胶、磷酸钙、藻酸盐、明胶、硅酸钙、微晶纤维素、聚乙烯吡咯烷酮、纤维素、水、糖浆、甲基纤维素、羟基苯甲酸甲酯、羟基苯甲酸丙酯、滑石、硬脂酸镁和矿物油,但并不限于此。除了上述成分之外,本发明的组合物还可以包括润滑剂、润湿剂、甜味剂、香料、乳化剂、悬浮剂和防腐剂。
在本发明的组合物中,包含噬菌体Esc-COP-1作为活性成分。此时,噬菌体Esc-COP-1为以下浓度1×101pfu/ml~1×1030pfu/ml或1×101pfu/g~1×1030pfu/g,优选1×104pfu/ml~1×1015pfu/ml或1×104pfu/g~1×1015pfu/g。
本发明的组合物可以由本领域技术人员通过使用单位剂量形式或在多剂量容器中的药学上可接受的载体和/或赋形剂通过本领域的方法来配制。制剂可以是在油或水溶性介质、提取物、粉末、颗粒、片剂或胶囊中的溶液、悬浮液或乳液的形式。此时,可以另外包含分散剂或稳定剂。
本发明的组合物可以根据使用目的制备为消毒剂、饮用水添加剂或饲料添加剂,但不限于此。
有益效果
使用包含噬菌体Esc-COP-1作为活性成分的组合物来预防和治疗产志贺毒素F18型大肠杆菌感染的方法与基于包括常规抗生素的化学物质的常规方法相比具有对产志贺毒素F18型大肠杆菌特异性高的优点。这意味着,本发明的组合物可以用于特异性预防或治疗产志贺毒素F18型大肠杆菌的感染,而不会影响其他有用的寄宿细菌,因此具有较少的副作用。一般来说,当使用如抗生素的化学物质时,一般寄宿细菌也会受到损害,从而削弱动物的免疫力,具有各种副作用。同时,本发明的组合物使用从自然界中分离的噬菌体作为活性成分,因此其非常自然友好。
附图说明
参考附图可以最好地理解本发明的优选实施方式的应用,其中:
图1是示出噬菌体Esc-COP-1的形态的电子显微照片。
图2是说明噬菌体Esc-COP-1杀死产志贺毒素F18型大肠杆菌的能力的照片。盘上的透明区域是通过溶解细菌细胞形成的斑块。
具体实施方式
本发明的实际和目前优选的实施方式如下列实施例所示。
然而,应当理解的是,本领域技术人员在考虑本发明公开内容的基础上可以在本发明的精神和范围内进行修改和改进。
实施例1:分离能够杀死产志贺毒素F18型大肠杆菌的噬菌体
从自然界中收集样品以筛选能够杀死产志贺毒素F18型大肠杆菌细胞的噬菌体。用于本文中噬菌体分离的产志贺毒素F18型大肠杆菌是本发明人之前已经分离并鉴定为产志贺毒素F18型大肠杆菌的产志贺毒素F18型大肠杆菌。
噬菌体的分离过程在下文中详细描述。将收集的样品加入到TSB培养基(胰蛋白酶大豆液体培养基)(酪蛋白的胰消化物,17g/L;大豆的木瓜酶消化物,3g/L;葡萄糖,2.5g/L;氯化钠,5g/L;磷酸氢二钾,2.5g/L),以1/1000的比例接种产志贺毒素F18型大肠杆菌,然后在37℃下振荡培养3-4小时。培养完成后,以8000rpm离心20分钟,回收上清液。回收的上清液以1/1000的比例接种产志贺毒素F18型大肠杆菌培养物,然后在37℃下振荡培养3-4小时。当样品含有噬菌体时,为了提高噬菌体的滴定度,将上述步骤重复5次。重复步骤5次后,培养物溶液以8000rpm离心20分钟,回收上清液。回收的上清液用0.45μm过滤器过滤。将得到的滤液用于斑点测试,以检查是否包括能够杀死产志贺毒素F18型大肠杆菌的噬菌体。
斑点测试如下进行:以1/1000的比例在TSB培养基上接种产志贺毒素F18型大肠杆菌,37℃振荡培养过夜。将上述制备的3ml产志贺毒素F18型大肠杆菌培养液(OD600=1.5)涂在TSA(胰蛋白酶大豆琼脂;酪蛋白的胰消化物,17g/L;大豆的木瓜酶消化物,3g/L;氯化钠5g/L;琼脂,15g/L)板上。将板放在小室内干燥约30分钟。干燥后,将10μl所得滤液直接点在产志贺毒素F18型大肠杆菌苔的表面上并干燥约30分钟。干燥后,将板在37℃培养一天,然后检查在细菌苔表面上透明区域的形成。如果在滤液滴下的地方产生透明区域,则可以判断为滤液中包含能够杀灭产志贺毒素F18型大肠杆菌的噬菌体。通过上述步骤,可以获得含有具有杀死产志贺毒素F18型大肠杆菌能力的噬菌体的滤液。
之后,从上述确认具有能够杀死产志贺毒素F18型大肠杆菌的噬菌体的滤液中分离出噬菌体。常规的斑块测试用于纯噬菌体的分离。具体来说,通过使用灭菌的尖端拾取斑块测试过程中形成的斑块,然后将其加入到产志贺毒素F18型大肠杆菌的培养液中,然后培养4-5小时。培养完成后,以8000rpm离心20分钟,得到上清液。在回收的上清液中以1/50的比例接种产志贺毒素F18型大肠杆菌培养物,然后再培养4-5小时。为了增加噬菌体的滴定度,将上述步骤重复至少5次。然后,以8000rpm离心20分钟,得到上清液。用获得的上清液进行斑块测试。一般来说,纯噬菌体分离不是一次性完成的,因此通过使用上述形成的斑块重复上述步骤。在重复步骤至少5次后,得到含有纯噬菌体的溶液。通常重复分离纯噬菌体的步骤,直到产生的斑块在尺寸和形态上相似。通过电子显微镜观察确认最终的纯噬菌体分离。直到在电子显微镜下确认纯噬菌体分离之前,重复上述步骤。在电子显微镜下的观察用常规方法进行。简言之,将含有纯噬菌体的溶液装载在铜格栅上,随后用2%的乙酸铀酰阴性染色。干燥后,在透射电子显微镜下观察形态。本发明中分离出的噬菌体的电子显微镜照片如图1所示。从形态上观察,上述分离的噬菌体被鉴定为属于肌尾噬菌体科噬菌体。
含有上述确认的纯噬菌体的溶液进行纯化。将产志贺毒素F18型大肠杆菌的培养液以噬菌体溶液总体积的1/50的体积加入到含有纯噬菌体的溶液中,然后再培养4-5小时。培养完成后,以8000rpm离心20分钟,得到上清液。重复该过程5次,得到含有足够数目噬菌体的溶液。将最终离心得到的上清液用0.45μm过滤器过滤,然后用常规聚乙二醇(PEG)沉淀。特别地,将PEG和NaCl加入到100ml滤液中,直到达到10%PEG8000/0.5M NaCl,在4℃下静置2~3小时。然后,以8000rpm离心30分钟,得到噬菌体沉淀物。将所得噬菌体沉淀物重新悬浮于5ml缓冲液(10mM三羟甲基氨基甲烷盐酸盐,10mM MgSO4,0.1%明胶,pH 8.0)中。该溶液被称为噬菌体悬浮液或噬菌体溶液。
结果,收集上述纯化的噬菌体,将其命名为噬菌体Esc-COP-1,然后于2014年8月21日在韩国生物科学和生物工艺学研究院韩国典型培养物保藏中心保藏(登记号:KCTC12662BP)。
实施例2:噬菌体Esc-COP-1基因组的分离和序列分析
如下分离噬菌体Esc-COP-1的基因组。将基因组从实施例1获得的噬菌体悬浮液中分离。首先,为了去除悬浮液中的产志贺毒素F18型大肠杆菌的DNA和RNA,将脱氧核糖核酸酶I和核糖核酸酶A各200U分别加入到10ml的噬菌体悬浮液中,在37℃下培养30分钟。30分钟后,为了去除脱氧核糖核酸酶I和核糖核酸酶A活性,加入500μl 0.5M乙二胺四乙酸(EDTA),培养10分钟。将悬浮液在65℃下进一步培养10分钟,然后加入100μl蛋白酶K(20mg/ml)以破坏噬菌体的外壁,然后在37℃下培养20分钟。之后,加入500μl 10%十二烷基硫酸钠(SDS)溶液,然后在65℃培养1小时。加入10ml比例为25:24:1的苯酚:氯仿:异戊醇混合物,然后充分混合。将混合物以13,000rpm离心15分钟以分离每层。得到上层液体,向上层加入体积为上层体积的1.5倍的异丙醇,然后以13,000rpm离心10分钟以沉淀噬菌体的基因组。收集沉淀后,向沉淀物中加入70%乙醇,然后以13,000rpm离心10分钟以洗涤沉淀。回收洗涤的沉淀物,真空干燥,然后溶于100μl水中。重复该步骤以获得足够量的噬菌体Esc-COP-1基因组。
通过在首尔国立大学环境管理国家仪器中心使用illumina Mi-Seq装置进行下一代测序(NGS)分析上述获得的噬菌体Esc-COP-1基因组的核苷酸序列。结果表明,噬菌体Esc-COP-1的最终基因组的大小为169,717bp,全基因组的核苷酸序列为SEQ ID NO:1。
通过使用网站(http://www.ncbi.nlm.nih.gov/BLAST/)上的BLAST研究了上述获得的噬菌体Esc-COP-1的基因组序列与先前报道的噬菌体基因组序列的相似性。从BLAST结果看,确认的是噬菌体Esc-COP-1的基因组序列与大肠杆菌噬菌体vB_EcoM_ACG-C40(基因库登记号:JN986846.1)、大肠杆菌噬菌体RB14(基因库登记号:FH839692.1),大肠杆菌噬菌体HY01(基因库登记号:KF925357.1)、大肠杆菌噬菌体RB51(基因库登记号:FJ839693.1)和大肠杆菌噬菌体RB68(基因库登记号:KM607004.1)的序列具有很高的序列同源性(96%,96%,97%,95%和95%)。然而,他们的基因组大小彼此有区别。确切地说,噬菌体Esc-COP-1的全基因组大小测定为169,727bp,而大肠杆菌噬菌体vB_EcoM_ACG-C40的全基因组大小为167,396bp,大肠杆菌噬菌体RB14的全基因组大小为165,429bp,大肠杆菌噬菌体HY01的大小为166,977bp,大肠杆菌噬菌体RB51的大小为168,394bp,大肠杆菌噬菌体RB68的大小为168,401bp。此外,噬菌体Esc-COP-1基因组内的ORF(开放阅读框)的数量被确定为275个ORF,而大肠杆菌噬菌体vB_EcoM_ACG-C40中的ORF数为273个ORF,大肠杆菌噬菌体RB14为274个ORF,大肠杆菌噬菌体HY01为257个ORF,大肠杆菌噬菌体RB68为276个ORF。但大肠杆菌噬菌体RB51基因组内的ORF数为275个ORF,与噬菌体Esc-COP-1相同。然而,大肠杆菌噬菌体RB51基因组内的ORF排列与噬菌体Esc-COP-1的排列截然不同。
基于该结果得出结论,噬菌体Esc-COP-1应该是以前未报道的新型噬菌体。
实施例3:噬菌体Esc-COP-1对产志贺毒素F18型大肠杆菌的杀伤能力的研究
研究了分离的噬菌体Esc-COP-1对产志贺毒素F18型大肠杆菌的杀伤能力。为此,通过与实施例1中所述相同的方式通过斑点测试观察透明区域的形成。用于该研究的产志贺毒素F18型大肠杆菌共有10个菌株,其之前已经由本发明人分离并鉴定为产志贺毒素F18型大肠杆菌。噬菌体Esc-COP-1显示了对本实验中使用的9个产志贺毒素F18型大肠杆菌的杀伤能力。杀伤能力试验的代表性结果如图2所示。同时,还研究了噬菌体Esc-COP-1杀死金黄色葡萄球菌(Staphylococcus aureus),粪肠球菌(Enterococcus faecalis),屎肠球菌(Enterococcus faecium),植物乳杆菌(Lactobacillus plantarum),乳房链球菌(Streptococcus uberis)和铜绿假单胞菌(Pseudomonas aeruginosa)的活性。结果是,确定了噬菌体Esc-COP-1不具有针对这些微生物的杀伤活性。
因此,证实了噬菌体Esc-COP-1具有杀死产志贺毒素F18型大肠杆菌的特异性能力和针对产志贺毒素F18型大肠杆菌的广谱抗菌谱,这表明本发明的噬菌体Esc-COP-1可用作用于预防和治疗产志贺毒素F18型大肠杆菌感染的组合物的活性成分。
实施例4:噬菌体Esc-COP-1对产志贺毒素F18型大肠杆菌感染的预防作用
将100μl噬菌体Esc-COP-1溶液以1×108pfu/ml加入到含有9ml TSB的试管中。对于含有9ml的TSB的另一个试管,仅添加相同体积的TSB。然后,将产志贺毒素F18型大肠杆菌培养物加入到每个管中以制备OD600为0.5的细菌悬浮液。之后,将试管转移到37℃的培养箱中,然后振荡培养,期间观察产志贺毒素F18型大肠杆菌的生长。如表1所示,在添加有噬菌体Esc-COP-1溶液的管中,产志贺毒素F18型大肠杆菌的生长受到抑制,而在没有噬菌体Esc-COP-1溶液的管中,产志贺毒素F18型大肠杆菌的生长没有被抑制。
表1
产志贺毒素F18型大肠杆菌的生长抑制
上述结果表明,噬菌体Esc-COP-1不仅抑制产志贺毒素F18型大肠杆菌的生长,而且可以杀死它们。因此,噬菌体Esc-COP-1可以用作用于防止产志贺毒素F18型大肠杆菌感染的组合物的活性成分。
实施例5:噬菌体Esc-COP-1对产志贺毒素F18型大肠杆菌感染的治疗作用
研究了噬菌体Esc-COP-1对受产志贺毒素F18型大肠杆菌影响的动物的治疗作用。4只25天大断奶仔猪为一组,共2组猪在猪圈(1.1米×1.0米)中饲养14天。安装供暖系统,控制周围环境。控制猪圈的温度和湿度,每天清洁地板。在实验的第7天,使用口服注射管给所有动物口服1mL产志贺毒素F18型大肠杆菌悬浮液。上述给药的产志贺毒素F18型大肠杆菌悬液制备如下:将产志贺毒素F18型大肠杆菌在TSB培养基中于37℃培养18小时,通过离心收集细菌细胞。将盐水(pH7.2)加入到细菌细胞沉淀中以使细胞悬浮液浓度为109CFU/ml。从产志贺毒素F18型大肠杆菌激发的第二天起,实验组(噬菌体溶液处理的猪)以与上述给药相同的方式口服给药噬菌体Esc-COP-1(109PFU/头)一天两次。对照组(噬菌体溶液未处理的猪)无任何处理。给两组提供同样的饲料和饮用水。在产志贺毒素F18型大肠杆菌激发之后,每天都观察动物是否发生腹泻。通过测量腹泻指数进行观察。根据粪便一致性(FC)评分(正常:0,松散粪便:1,中度腹泻:2和严重腹泻:3),腹泻指数设定如下。结果示于表2。
表2
粪便一致性评分
从上述结果可以确认,本发明的噬菌体Esc-CHP-1可以非常有效地治疗由产志贺毒素F18型大肠杆菌引起的感染。
实施例6:饲料添加剂和饲料的制备
使用噬菌体Esc-COP-1溶液制备含有浓度为1×108pfu/g的噬菌体Esc-COP-1的饲料添加剂。其制备方法如下:向噬菌体溶液中加入麦芽糖糊精(40%,w/v),然后加入海藻糖到终浓度为10%。混合均匀后,将混合物冷冻干燥。最后,将干燥的混合物研磨成细粉末。上述干燥过程可以用真空干燥、温热干燥或在室温下干燥来代替。为了制备对照饲料添加剂进行比较,制备不含噬菌体但仅含有缓冲液(10mM三羟甲基氨基甲烷盐酸盐,10mM MgSO4,0.1%明胶,pH8.0)的饲料添加剂。
将上述两种饲料添加剂分别与1000倍体积的猪饲料混合,得到两种最终的饲料。
实施例7:饮用水添加剂和消毒剂的制备
饮用水添加剂和消毒剂在使用目的上不同,但组合物相同,因此它们以相同的方式制备。使用噬菌体Esc-COP-1溶液制备含有浓度为1×108pfu/ml的噬菌体Esc-COP-1饮用水添加剂(或消毒剂)。特别地为了制备饮用水添加剂(或消毒剂),将噬菌体Esc-COP-1溶液加入到缓冲溶液中达到1×108pfu/ml,混合均匀。为了比较,将上述缓冲溶液本身用作不含噬菌体的饮用水添加剂(或消毒剂)。
制备的两种饮用水添加剂(或消毒剂)以1:1000的比例在水中稀释,然后用作饮用水或消毒剂。
实施例8:对养猪业的影响
研究了实施例6和实施例7中制备的饲料、饮用水和消毒剂对养猪业的影响。特别地,研究重点是通过实施例5中粪便一致性评分的腹泻情况。共30只仔猪分为3组,每组由10只仔猪组成(A组:饲料试验组,B组:饮用水试验组;C组:消毒剂试验组)。实验持续2周。每组分为两小组,每小组包括5只仔猪。根据噬菌体Esc-COP-1处理与否分组(小组①:用噬菌体Esc-COP-1处理;小组-②:未用噬菌体处理)。在该实验中使用的仔猪是20天大的断奶仔猪,并且在分开的彼此间隔足够距离的房间中饲养。每个小组如表3所示被划分并命名。
表3
养猪实验的小组
按照表3所示的常规饲料供给方法提供饲料,提供实施例6中制备的饲料。根据表3中所示的常规供水方法提供饮用水,提供实施例7中制备的饮用水。消毒剂与常规消毒剂一起轮流处理,一周三次。也就是说,在喷洒本发明的消毒剂的那一天,没有用常规的消毒剂进行处理。结果示于表4。
表4
养猪实验的粪便一致性评分
从上述结果可以确认,本发明制备的饲料、饮用水和消毒剂在降低动物腹泻方面是有效的。因此,可以得出结论,本发明的组合物可以有效地用于提高动物养殖的生产率。
本领域技术人员将理解的是,在前面的说明书中公开的概念和具体实施方式可以容易地被用作修改或设计用于实现本发明的相同目的的其他实施方式的基础。本领域技术人员还将理解的是,这些等同的实施方式不脱离如所附权利要求中阐述的本发明的精神和范围。
保藏单位名称:韩国生物科学和生物工艺学研究院
保藏编号:KCTC12662BP
保藏日期:20140821
序列表
<110> 尹特荣生物科技株式会社
<120> 新型产志贺毒素F18型大肠杆菌噬菌体Esc-COP-1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途
<130> DFP17KR3052
<160> 1
<170> PatentIn 版本 3.2
<210> 1
<211> 169727
<212> DNA
<213> 噬菌体 Esc-COP-1
<400> 1
ctaaattagt taatagtata gcgccaggaa catataaaaa ggaaatacct gagcctcgtc 60
ttgttattcc aatttataat gctaacggaa aagccgagtc ttttcaagga cgtgcattaa 120
agaaagatgc tccccaaaaa tatatcacca tcaaagctta tcctgaggca acaaaaatct 180
atggagttga acgagtcaaa gatggtgatg tatatgttct agaaggacct atagattcac 240
tttttattga aaatggtata gctattacgg gtggtcaatt agacctagaa attgttccat 300
ttaaagatag acgtgtatgg gttttagata atgaacctcg tcatcctgac actattaaac 360
gaatgactaa attagttgat gcaggagaaa gggttatgtt ttgggacaaa tctccctgga 420
aatcaaaaga tgttaatgat atgattagaa aggaaggtgc aacccctgaa caaattatgg 480
aatatatgaa aaataatatt gctcaagggt tgatggctaa aatgcggcta tctaaatatg 540
ctaagattta aattaaccca actaaagcaa atgctaaatc tacgaatgta tcaagagtaa 600
ttactggaat attaacgcca tgagcaatag caattggcga taaaacaaaa ttccagagta 660
aaattcctac catagcagaa atagtaaaag ctatacgttt cttattacct tttatggcat 720
taacaagtgc cattaatttt tgtaccatgc gtcgtcctcc tttaaattaa atatttatcg 780
caaattttac aaaatttgtt tacttcctcg gttagttgtg gtattataaa ataaactgct 840
gaggataata taatgattaa taaaattgta catgaaatgg ctttaaacgg agattcatat 900
aaaatatctg ccgtagttga gaatttcata cttaataaag tgaaagagta tttcactgat 960
tgctcagtta gttatcaaga aaaaatggtt ttaactgacg atactgaaaa atcaaataat 1020
ttgttttgct cgaattttac aactaaaaag cgtactagaa gatttgatat tgtcatttct 1080
cgcaatggta aaaagcatat aattgaaatt aaacaccaag ttggtggagg tacagctatt 1140
gattctgttg gaatatattt agaagataaa gataaattaa aagaatacac aaaaactgaa 1200
acccctgtgt cattaatgat attagatttt tttgccatgc ggttattatc cacgcaataa 1260
atggacaaaa agagaatcat ttactgataa tccaactatt caggcaaggt ttaatgaata 1320
tgctaaatca caaaacgtgt tagtattact atcaaataca tatgatgaag aattatataa 1380
ttcgtttttt gctgcaataa atgagagaat ataatgttag gagctatcgc gtatacaggt 1440
aataaacagt cattattacc tgaacttaag cctcactttc caaaatatga cagattcgta 1500
gatttatttt gtggaggttt atcagtgtct ttgaatgtca atggtcctgt attggctaat 1560
gatattcaag aaccaattat tgaaatgtac aagcgtctta ttgatgtatc atgggatgac 1620
gttttaaaag taataaagca atacaaattg tcaaaaacat caaaagaaga gtttttgaaa 1680
ttgcgtgaag attataataa aactagagat cctcttttgc tttatgttct tcattttcat 1740
gggtttagta atatgattcg tataaatgac aaaggaaatt ttactactcc atttggaaaa 1800
agaactataa acaaaaatag tgaaaaacgt tttaatcact ttaaacaaaa ttgtgataaa 1860
ataatcttca gttcattgca ttttaaagat gtcaaaattt tagatggcga ttttgtatat 1920
gttgatcctc catacctcat aacagttgcc gattataata aattttggtc agaagacgaa 1980
gaaaaagacc ttttaaatct tttagactct ttaaatgaca gaggaataaa atttggattg 2040
tcgaatgttt tagagcacca cggaaaggaa aacgctcttc ttaaagaatg gtctaaaaaa 2100
tataatgtta agcatcttaa taaaaaatac gtctttaaca tacatcattc caaagaaaag 2160
aatggaactg atgaagtata tatttttaat taattgctta tatattcaaa tgatataatt 2220
atttaactta ttaatgaatt gaaaggaaaa ataatggcat attttaacga atgttcacaa 2280
ctgattgaag gcgctgataa agctcaaaat gaatactggg atattctcgg tgatgaaaaa 2340
gacccgctgc aggttatgct tgatatgcag aaatctctgc aagttcgttt agctaaagat 2400
aagcctgaat ataaccgtca tcctgatgat ttggctactg caggtgaagt tgttgattgg 2460
ttgcgtaatc agaaagatta tattgatgat gaattccgcg aacttctgac ttctcttggt 2520
ggtatgagca atggtgaaaa agatgcatct gctgtatgga agccttggaa gtcgcagcat 2580
ggtgaacgtc gtgaaactct gattactgat ttgtctccac aagaccagtt ggaaattaaa 2640
ttcgaaatga ttgatattct tcatttcgtt ctgaacatgt tccaaggtct tggtcttacg 2700
gctgaagaaa tctttaaact ttattatctg aaaaatgctg aaaactttgc tcgtcaagac 2760
cgaggttatt aatagctcgt ttatttaaac gacgacttaa aagccgtgag aattattata 2820
aataatcatg taatttaaat aaaaggagaa ttacatggct agtactcgcg gttatgttaa 2880
tatcaaaacg tttgagcaga aattagatgg aaataagaaa attgaaggaa aggaaatttc 2940
tgtagctttc cctctttatt ctgacgttca caaaatttct ggcgctcatt atcagacatt 3000
cccttcagaa aaagcagcat atactactgt atatgaagaa aatcaacgcg ctgcgtggat 3060
tgctgcaaac gaagatttgt ggaaagtaac tggtgaataa attcagggac tccttcagga 3120
gtcctttttt cattttaccg gtttactttc cacaatgagt atggtataat agaattatct 3180
tatagaggag agcactatgt taaatcgttg gattaaacca aatgaagacc tccagaaggt 3240
tcttgataaa gctatctctg ataaatgggg tatgaaaagc tgggattgtg atatcgtcac 3300
gcattcattc atgatgcatg cagatggttc agtcgagttc aatgctgaaa tgcgatacac 3360
tgactggggt ggatttcaaa gagtcgaatt tcaaagaggc tttttgtaat gtttatcttt 3420
aattggttta aaagtttctt tacggatttt ttctctacga ctccgggaga aggtgtagtt 3480
cctattacaa atgactacct tcctttaact gtagttgaat atgtttatat gggagatgga 3540
acagtagaag cagttactat gacttatgaa gaagcccagg aatattataa aaatccttgg 3600
cgttggtcaa cacctacatc atctaatacg cagaatacac agtctagttc tgattcatat 3660
gacactaatg ttcctgttca tgtatggacg ggagattcat gtggaagttc ttgtgattct 3720
agttgttcat ctacatcttg tgattgagga aaattatgga agcgattttg tttgaaatgt 3780
atattagcag taatagtttg tcgtttgcta aagacgttcc aattaccgta gcagtaatga 3840
ttgataaggg ttattgtgac ccaatgtatc tcgtagaaaa tttcgtttca atgccagttc 3900
cagaagatgc tgaaataaaa cttaaaaaga ttggtattat tgaaactgta ccaaatattc 3960
catttagagc aattgaagca tttactaaat ccgaatacat caatgttagc gcagaacaat 4020
ataatgataa ccctttatct ttttattcgt acgattcagt atatgactgg aaaatagata 4080
aaggaaataa atttataatt gcgagtgaag atgctttatc atactttatt tcttctgtat 4140
ggaatagttt acatccaaat ttgctaaaaa ttcatgaatt tgatgatgct cctactattg 4200
ttttaggtaa aacaaatgaa aattctgaag aagatgcttg aatggttcag tagaccaagc 4260
tcaatgtata ttgacgatgg ttgggttgaa caagcaaata aagaaatgca gaacgaatcg 4320
gaagaatgga tgaaatcaat gattagtgct gagaaagaaa agaaattaga acgctcagca 4380
cttaaattaa tgagagacat ctatggggat aaatcgtgaa caaagatatg acattagaag 4440
aggctaaagc taaagcaaac gaagcactgg atttgcttct taaaatcggt agtaaaatga 4500
tggaagaaaa tgagaaatac attcaggaaa acaaaattcc tgacggtcca ttagtaggca 4560
aaaggaaatc acatgattga agtagcaaaa cgttattcaa tagaatttat gtctaaagaa 4620
ggtaaatcag taaatacact taataaaaat tgctcattaa ttattccttt agcagaaaat 4680
ccggatcatt taattaaaga tataaaagaa agaaaatatc cagaaaatgt tattctagtt 4740
ataaagcata ctgaagatat tttgcataat acagattcac cgttttcttc ttctgaagct 4800
ttaactatta aaggctataa aagagctcat gaatatggtc tttttgacct gtttgaagac 4860
gataaagtta aattagctag tcaaccttct aaaagtaaaa cattcattat tgaagatatt 4920
aaagatataa atgcatttat taagatggtc tgggctcatt ttgatgttgg actacgctgg 4980
agaatgtccg aagaagaaag aaagattatt gaagctaatc gtcattttgg tttttatcgc 5040
taggaattaa tatggattta tttgagatgt tagaagataa tcattctacg aatatccaga 5100
atgattctag tgattataag aaagagtacc gtatagtatt acagaattat ggaattgaag 5160
ccccagatgc tcttctagaa gaactagctt cataccatct tgaccctccg ccctgggctc 5220
cctgggcaaa ataattcaaa aagttgttta ctttccttcc taacaatgat atgatagctt 5280
ctgaagtata tggaggctat catgattatt aatctcgcag atgttgaaca gttatctata 5340
aaagctgaaa gtgtcgattt tcaatatgat atgtataaaa aggtctgtga aaaatttact 5400
gactttgaac agtcagttct ttggcaatgt atggaagcca aaaagaatga agctcttcat 5460
cagcagttga ataaaatcgt taaaaagcat ttaactaaat cgccttatca gctatatcgt 5520
ggtatatcaa aatcgacaaa agaactcatt aaagatttac aagtcggaga agtgttttca 5580
acgaacagag tagattcatt tactactagt ttgcatacag catgcggttt ttcttatgtt 5640
gaatattcca ctgaaataat atttcgctta aaaactgata aagcttttaa ttattctgac 5700
catatcagcg atattatact ttcttctcct aatactgagt ttaagtatac atatgaagat 5760
actgatggat tagattcaga acgtactgat aacttaatga tgattgtacg tgaacaagaa 5820
tggatgattc caattggaaa gtataaaata acttctattt caaaagaaaa attacacgat 5880
tcatttggaa catttaaagt gtatgatatt gaggtagttg aatgaaatat tcagcaatgc 5940
aattaaaaga ttttaaaata aaatcaatgg atgcatcggt gcgtgcttct attcgcgaag 6000
aattactttc tgaaggattt aatttatccg aaattgaact tttaattcat tgtattacta 6060
ataagccaga cgatcattct tggttaaatg aaataatcaa atctcgtttg gttccaaacg 6120
ataaacctct ttggagaggt gttccagttg agactaagca ggtattaaat caaggaattg 6180
atattattac atttgataaa gtagtatcag cttcatatga taaaaatata gctctacatt 6240
ttgcttctgg attagaatac aacacacaag ttatttttga attcaaagct cctatggtgt 6300
ttaatttcca ggagtatgct ataaaagctc tacgttgtaa agaatatagt ccgagtttta 6360
aatttccgga tagccatcgc tatcgtaata tggaattagt ttcagatgaa caagaagtaa 6420
tgataccagc tggaagtgta tttagaattg cggatagata cgagtataaa aagtattcaa 6480
catacactat ctatactctt gactttgaag gatttaatct ataatggaag gacttagatt 6540
cattatacca tgaaagtttt aaagcatttt tcataaagtt gtttacaaac tgaagtaaaa 6600
atgttatagt ataagtagtt aaccgtccgt gagaaaaata tgaaactgtc taaaaatcaa 6660
attcgtaaaa ttacacgtcg tctagagcat acccaggcat ctgctaaaag acgttctaaa 6720
gattttaact tagacttcaa ttacattaag aacattttag atcagaaagt ttgcgcttac 6780
tcgggagaac cttttgataa tcgtattgaa ggagagaaat tatcattaga acgttttgat 6840
aataacgttg gatacattaa agggaatgtt attgcagtaa agaaaaagta taatacattt 6900
cgttctgatt atactttaga agagttgatt gaaaagcgtg atttatttgc tttgcgaatt 6960
ggtcgttcat ctgcgaaaaa agttcataaa ctaaatttag atgaaaagaa atgggctaaa 7020
atcaaaaaga cttataatca aattaaagct atacagaaaa aacgtgaaaa tcgaattgaa 7080
cacatttctc agctttctaa atcaaaacaa acctctgata ttaagctaac gattgtagca 7140
ctcaaagctc gtattgatgg ttctcgtata gcagaaggca ctgaagttgt taaattgaac 7200
gttcttctta aaggctctga ttggaaaact gtgaaaaagt tgtcagaagc agaaatgcaa 7260
tatgatatgt gtgataaaat tattcaaggt gtagagcggt atcaaaactt gtcttttatt 7320
gataaactta aactgaaaag aggatacccg ctaaattgtt caatttttaa acttatccga 7380
ggataatatg ttttatgtat atgcgatagt gtatagagac aaagatggat ttgcagtgcc 7440
tgttccgctt gatgaacatc gccctgctgt attttttgaa agggagattg ctgataaagt 7500
atttaccact cttaaagagc agtatcgact agctttaggt atgggaattc cgagattagt 7560
tgagactcca cgcaagtttt ggtttaataa aatagaagtt aaacatgtta agcctgatat 7620
agacacacaa agattatatc ggcgaatttt agatactggg cgtattgtta gtataccaat 7680
tgcagggaat ttacgatgac atttgatgat ttgaccgaag gccagaaaaa tgcctttaac 7740
atcgttatga gggctattaa agaaaagaaa catcatgtaa ctattaatgg acctgctggt 7800
actggtaaga ctactcttac taagttcatc attgaagcct taatatctac gggcgaaact 7860
ggcattattt tagcagctcc tacacatgcg gctaaaaaga ttctttcaaa actatcaggg 7920
aaagaagcga gtactattca cagtattctt aaaattaacc cagtaacata tgaagaaaac 7980
gttctttttg aacaaaaaga agtaccagat ttagctaaat gtagagtatt aatctgcgac 8040
gaagtgtcaa tgtatgatag aaagctattt aaaattctgc tttcaactat tccaccttgg 8100
tgtactataa ttggaatagg cgataataag caaattagac ctgttgaccc aggagaaaac 8160
accgcttata tcagtccgtt ctttacacat aaagattttt atcagtgtga actcactgaa 8220
gttaaacgca gtaatgctcc tattattgat gtagctactg atgttcgcaa cggtaagtgg 8280
atttatgata aagttgttga cgggcatgga gtacgtggat ttactggtga taccgcttta 8340
cgtgatttta tggtaaatta tttttcaatc gtaaaatcac tagacgattt gtttgaaaat 8400
cgcgtaatgg catttacgaa taaatctgtt gataagttaa atagcattat tcgcaaaaag 8460
atttttgaaa ctgataaaga ttttatcgtt ggtgaaatta ttgtaatgca ggaaccatta 8520
attaaaacat ataaaattga tggaaagcct gtgtcagaaa ttatttttaa taacggacaa 8580
ttagttcgta ttatagaagc agagtataca tcaacgtttg ttaaagctcg tggtgtttct 8640
ggagaatatc taattcgtca ttgggattta acagtagaaa cttacggcga tgatgaatat 8700
tatcgcgaaa agattaaaat aatttcatct gatgaagagc tgtataagtt taacttattt 8760
ttaggtaaaa cggcagaaac ttataaaaat tggaataaag gtggaaaagc tccgtggagt 8820
gatttttggg atgctaaatc acagtttagt aaagtgaaag cacttcctgc atcaacattc 8880
cataaagctc agggcatgtc tgtagaccgt gctttcatct atacgccttg tattcattat 8940
gcagatgctg aattggctca gcagcttctt tatgttggtg tcactcgtgg tcgttatgat 9000
gtgttttatg tatgattaaa tttgaggaag ctattcgtgg aaataactaa agaccagttt 9060
tatctacttc aagataaagt gagcgaaata tatgaaatag cttatagtaa aaatcgcaaa 9120
aacgtgaaaa ttgaatcagg caagttaatg cttcaattgg aagaaattga acgagatttg 9180
attgcgttag aattcttttg tggtgaagtg aaaactgtta caatcagtga ttatatttta 9240
ggcgaaatta gccatcttta taaggcggtt attaatgatt gaattaagtt tacatcagtt 9300
taaatctctt atgacaaatg ttaaagctgt cattgaggaa aatccaggac ctgataatgt 9360
tactattcgc gaaaaagctt caaagatagt atacagtctt gaagagatac aaaaagatat 9420
tgaatctatg gcaaaattta ttgatgagcc cattaataaa gtttatatcc aagattatac 9480
tgtaggtcaa attcgcgatt tagcaaggaa aatttaatgt ttgattttat tatagatttt 9540
gaaacaatgg gaagcggtga aaaagcagct gttattgatt tggctgttat tgcctttgac 9600
cctaacccag aagtggttga atcatttgat gaattagttt cgcgcggcat taaaatcaaa 9660
tttgatttaa aaagtcaaaa aggacatcgt ctttttacta aaagcactat cgaatggtgg 9720
aaaaatcagt ctcctgaagc tcgaaaaaat attgcgccat cagatgaaga tgtaagcact 9780
atcgatggta ttgtaaaatt taatgattac atcaatgcgc ataatatcga tccttggaaa 9840
tctcagggtt ggtgccgtgg aatgtcgttt gattttccaa ttttagtcga tctcattcgc 9900
gatattcaac gtcttaatgg cgtttctgag aatgaacttg acacatttaa gttagaacca 9960
tgtaaattct ggaatcagcg tgatattcgt accagaattg aagcacttct ccttgttcgt 10020
gatatgacca cgtgtcctct tccaaaagga actttaaatg gattcgttgc acatgattct 10080
attcatgact gtgcgaaaga catcctgatg atgaagtatg ctttgcgata tgctatgggt 10140
cttgaagatg ctccgtcaga agaagagtgc gatcctctat ctcttccaat aaaacgataa 10200
aaagtagcta ttttgaatta atagtttaca aactcttggg accagagtat aatggtcccg 10260
tggagcataa aatcttttta acaagtgaga gataactatg attattaata ttggtgaaat 10320
tgctcgtgta tctgataaat cccgttctaa agcagcagga aaattggttg aaattgtaag 10380
cattcagctt aaacatggtg ttaaagatga agattctgaa gtaaaagtgc gtatcattcc 10440
taaagatgga aagtctaaac cccagtttgg atatgttcgc gcgaaatttc ttgagtctgc 10500
gtttttgaaa gctgttcctg ctaaaggaat tgaaacgatt gatacttcgc acgtaggtgt 10560
agactttaag tggaaactcg gtcaagctat taagttcgtt gctccttatg aattcgaatt 10620
tactgaagat gaggaggggg ttgttcaaaa acaccgtact cgcgctatgt gtgcatacat 10680
taccgatcag tgggtagaag atggcgttaa gttgtacaac gcggtatttt taggaacata 10740
caaagtcatt cctgaaagct ggattaaaca ctatagcaaa gcccgctatg cataaagttt 10800
aaaatttttt cataaaacta tatacatcag tagttgatta tggtactata tcaatatcaa 10860
ctactgatac agaaaacaac ttggagaata aaatggaaaa cttaattatc atcgaacaat 10920
ctttcaacga ttatggtatg gcttacggtt atcgtgcgat aatggaagat tctcgtggat 10980
gtgttatcga tattgctgaa tgtaaagatt tactgcagct tttgaagatt gttcgcaaaa 11040
attgggattg tgaaaacatt aaagctcgtg ttgtaacgga agaagaaact gtttttcatg 11100
atgtaaaatt cgccaaaggt gttgctactc ttctgaaacg catcgctcca ctgttcaatt 11160
aatgaggaaa ttgtaatgaa acgtaaaatt gttcagaatt gcactaatga tgaatttgaa 11220
gatgtattat tcgatccaga tttggtagta gttcaaaagg aacacactgc taagtttact 11280
cacttgactt cggtttatgt gtatgaaaag gttggtgata aacaaccaat ttacggtgta 11340
ttccgtgaaa tcactgaaga cggtacaact tactggaagg aaatttatta atggctatta 11400
gatttgaagt taataaatgg tatcaattta aaaataaaca agctcaagaa aattttatta 11460
aagaccatat taataacgga atctacgcgc gccgtttagg tatgtatcct tttaaaattt 11520
tagatgtgga cgctcttggg cgtcctatta aaattttgtc atctactgga aatttagtac 11580
tatctcctga taaagatgtt ttggatgaag actttatttg gctttcaaaa agtgaagctg 11640
ggttctttga tgaagttgaa aatccatacc aggcagctga agaacaagag caggaagagc 11700
aagaacaaat agaagatttc acagaatttc ctgtcatgaa agttactatt gaaaataatg 11760
aacatgcatg gtccttgtat cagatgttga aagcacactt taaggaataa ttatgccaat 11820
gtatgattat aaatgccaat ccaaagactg tgcaaaagaa tacgaaaaaa tcaagaaaat 11880
ttctgaaagg gatactgatg tatgtcctga ttgtcatcgg attgctattc ggttagtttc 11940
cgctcctaag catgtgaatg gtggatttta cgacttactt aaagggtgat tatgtttaaa 12000
atcggtaaga aatatcgtgt tcgcgaaggt gaagaaaaga aatatctact ttcttctatt 12060
tataggaatg gttctattaa tgccgtaata tctacaagcg aatttatcgt tgaagatatg 12120
aaaggtaata atgttacaat gattagtaca gcatctggaa atgatggaaa aattcttcac 12180
agttttcaga gtaatgttct aatttatgat gaagaatttg acttcttcga agaagttccc 12240
gaaggttttg attttgaatg tactatcact atgaaatctg gtgaccctct ttcttttaca 12300
gttaaagatg aaagaagtcg cttgagaatt attagtcttc ttcaagccat taaatttgag 12360
tgaaaattat gaaatatatt aatcgttcta tcgcggcatt agtattagca gtgtctttag 12420
caggatgtac tgatgctgat aatgcaacca aagttttgtc ttcaagtggg tttactaata 12480
ttgaaatcac tggatacaat tggttcggtt gctctgaaaa tgatttccaa catactggat 12540
ttcgtgctat tggacctacc gggcagaaag tagaaggaac cgtatgttct ggtctattct 12600
tcaaggattc gactatccgt tttaaataaa aggccttcgg gcctttagct ttatgattac 12660
cggagtataa tattcccgaa accaaacgag gataagtgat gattaagaat gaaattaaaa 12720
ttctgagcga tattgaacat atcaaaaagc gtagcggcat gtatattggt tcttctgcta 12780
atgaaatgca tgagcgcttt ctgtttggta aatgggaaag tgttcagtat gtacctggtc 12840
ttgttaagct tattgatgaa attatcgata actcagtaga tgaaggtatt cgtactaagt 12900
ttaaattcgc gaataaaatt aatgttacta ttaaaaacaa tcaagtaaca gttgaagata 12960
acggtcgtgg tattccacag gcaatggtta aaacacctac tggtgaagaa attcctggtc 13020
ctgttgctgc ctggactatt ccaaaagcag gtggtaactt cggtgatgat aaagaacgcg 13080
tcactggcgg tatgaacggt gttggttcta gtttaactaa tattttttct gtgatgtttg 13140
tcggtgaaac tggcgatggt caaaataata ttgtagttcg ttgttcaaat ggcatggaaa 13200
ataaatcatg ggaagatatt cctggaaaat ggaaaggaac tcgcgttact ttcattcctg 13260
attttatgtc atttgaaact aatgatctat ctcaagttta tcttgacatt acattagatc 13320
gtctccagac acttgcagta gtttatcctg atattcaatt tacctttaat ggtaaaaagg 13380
ttcagggtaa ttttaagaaa tatgcacgcc aatatgatga gcatgctatt gttcaagaac 13440
aagaaaattg ttctattgcg gttggtcgtt caccggatgg ttttcgtcaa ttaacatacg 13500
tcaataacat tcatactaag aatggtggcc atcatattga ctgcgttatg gatgatattt 13560
gtgaagacct tattccacaa atcaaacgta agttcaaaat tgatgtaact aaagcacgtg 13620
ttaaagaatg tttgactatc gttatgtttg ttcgtgatat gaaaaacatg cgatttgatt 13680
ctcagactaa agagcgtttg acttctccat ttggtgaaat tcgtagtcat attcagcttg 13740
atgctaaaaa gatttcacgc gctattttaa acaatgaaga aattttaatg ccaattattg 13800
aagctgcctt ggctcgtaaa ttggcggcag aaaaggcagc agaaactaaa gcagctaaaa 13860
aggcttctaa agctaaggtt cataaacata ttaaagcgaa tctttgcggt aaagatgctg 13920
atactactct tttcttgact gagggtgatt ctgctatcgg atatcttatt gatgttcgtg 13980
ataaagaact tcatggtggt tatccattgc gtggtaaagt tcttaacagt tggggtatgt 14040
cttatgctga tatgcttaaa aacaaagaac tgtttgatat ttgcgcaatc actggattag 14100
ttcttggtga aaaagctgaa aacttgaatt atcataatat tgctattatg actgatgctg 14160
accacgatgg tctaggaagc atttatcctt ctctgctcgg attttttagt aattggccag 14220
aactgtttga acaaggaaga attcgcttcg tcaaaactcc tgtaatcatc gctcaggtcg 14280
gtaaaaaaca agaatggttt tatacagtcg ctgaatatga gagtgccaaa gatgctctac 14340
ctaaacatag catccgttat attaagggac ttggctcttt ggaaaaatct gaatatcgtg 14400
agatgattca aaacccagta tatgatgttg ttaaacttcc tgagaattgg aaagagcttt 14460
ttgaaatgct catgggagat aatgctgacc ttcgtaaaga atggatgagc caatagttta 14520
ctttaccaca aggatgtggt ataattaatt gggcaaatga ggatattgaa atgaaatcat 14580
ataaagtaaa tttagaactt tttgataaag cagttcatcg agaatataga atcattcaac 14640
gctttttcga tatgggagaa gccgaagagt ttaaaaaccg ctttaaggat attagagata 14700
aaattcaatc cgacaccgca actaaagatg aactactaga agttgccgaa gttattaaac 14760
gcaatatgaa ttaatgagga aattatgatt atcaccactg aaaaagaaac aattcttggt 14820
aatggttcta aatcaaaagc atttagcatc acagcatctc ctaaagtatt taaaattcta 14880
tcatctgatt tgtatacaaa caagattcgt gcagtagtcc gtgaattgat taccaatatg 14940
attgatgccc atgctcttaa tggaaatcct gaaaaattta tcattcaagt tccaggacga 15000
ttagatccgc gatttgtttg tcgagatttt ggtccaggta tgagcgattt tgatattcaa 15060
ggtgatgata attctcctgg gttgtataat tcatacttta gttcatctaa ggctgaatct 15120
aacgatttca ttggcggatt tggtttaggt tctaaatctc cgtttagtta tactgataca 15180
tttagtatta cttcatatca taaaggtgaa attcgtggtt atgtagctta tatggatggc 15240
gatggtccgc agattaaacc tacattcgta aaagaaatgg gtccagatga taaaactggt 15300
attgaaatcg tagttccagt tgaagaaaaa gactttagaa actttgctta tgaagtttct 15360
tatatcatgc gaccattcaa agatttggct atcattaatg gtcttgaccg cgaaattgat 15420
tattttccgg attttgatga ttattacggc gtaaatccag aaagatactg gccagatcgt 15480
ggtggattat atgccatcta tggtggtatt gtttatccta tcgatggtgt tattagagac 15540
cgtaactggt taagcatccg caatgaagtg aattacatta agtttccaat gggttcactt 15600
gatattgctc catcacgcga agctctttca ctagatgatc gtactcgtaa aaatattatt 15660
gagcgtgtta aagagcttag tgagaaagca ttcaatgaag atgtaaaacg atttaaagaa 15720
tctacatctc ctcgtcatac ataccgtgaa ttgatgaaga tgggatattc tgctcgagat 15780
tatatgatta gtaattcagt caaatttacg actaaaaatc tgtcatataa gaagatgcaa 15840
agcatgtttg aacctgacag taagttatgc aatgcaggag ttgtgtatga agtaaatctt 15900
gaccctcggc tgaaacgtat taagcaaagc catgaaactt cagccgttgc atcaagttat 15960
cgtttgtttg gtattaatac aacaaaaatc aatatcgtta ttgataatat taaaaatcgt 16020
gttaatattg tccgtggatt agcgcatgcg ttagatgata gtgaatttaa taacactttg 16080
aatattcatc ataatgagcg tcttctgttt attaatcctg aagtagaatc gcagattgat 16140
ttactccctg atattatggc aatgtttgaa agtgatgaag ttaacattca ttatttgtca 16200
gaaattgaag ctttagttaa aagttatatt ccgaaggcag ttaaaagtaa agctcctcgt 16260
cctaaagctg ctactgcgtt taagtttgaa attaaagacg gacgctggga aaaagaggaa 16320
ctgtttacac tcacatcaga agcagatgaa attactggtt atgtagcata catgcatcgt 16380
tctgatattt tttctatgga tggtactaca tcgctttgtc atccatctac gagtattttg 16440
actcgtatag ctaatcttat tggcattaat gaattttatg ttattcgtcc acttttgcag 16500
aaaaaggtaa aagaacttgg tcagtgccaa tgtatttttg aaactctgcg tgatttatat 16560
gtagatgctt ttgatgctgt agattatgat aagtatgtag gttattcaag ttcagctaaa 16620
cgatatattg ataaaattat taagtatcct gaactcgatt ttatgatgaa gtacttcagt 16680
gtagatgaag tttctgaaga atatactcgc cttggtaata tggttagttc attgcagggt 16740
atatatttca acggtggaaa aggtaccatc ggtcatgaca tctggacagt aactaatctt 16800
tttgatgtat tatcaaataa tgcttcaaaa aatagtgata aaatggttgc tgagtttacc 16860
aagaaattcc gtattgtttc cgacttcatc ggttatcgca gctctttgag tgatgatgaa 16920
gtttcccaaa tcgctaaaac tatgaaggcc cttgcggcct aataaggaaa attatgtaca 16980
atattaaatg cctgaccaaa aacgaacaag ctgaaattgt caaactgtat tcaagcggta 17040
attataccca gcaggaattg gctgattggc aaggtgtatc agtggacaca atccgtcgtg 17100
ttttgaaaaa tgctgaagaa gctgagcgct ctaaagttac cattagcggt gatattacag 17160
ttaaagttaa tagcaataca gctattgctc cagttgctaa atctgacatt atttggaatg 17220
catctaaaaa attcatttca attactgttg atggtgtaac ttataacgca actcctaata 17280
ctcattcaaa cttccaggaa attcttaatc tgcttgttgc agataaattg gaagaagcgg 17340
cacaaaaaat taatgttcgt cgcgctgttg aaaaatatat ttccggtgat gttcgaattg 17400
aaggtggaag cttgttctat caaaatattg aattgcggtc tggtttagtt gatcgtattc 17460
tcgattcgat ggaaaaaggc gaaaactttg aattttattt tccgttcttg gaaaatctgt 17520
tggaaaaccc gagccaaaaa gcggtatctc gactctttga tttcttggta gcaaacgata 17580
ttgaaattac agaagatggc tacttttatg cttggaaagt agttcgcagc aattactttg 17640
actgccattc aaatactttt gataacagtc ctggtaaagt agttaaaatg ccacgtactc 17700
gtgtgaacga cgatgataca caaacttgtt ctcgtggtct gcatgtatgt tctaaatctt 17760
atattcgtca ctttggcagt tcaaccagcc gagttgtaaa agttaaagta catcctcgcg 17820
atgtagtatc aattccgatt gattacaacg atgctaaaat gcgtacctgc caatacgaag 17880
tagttgaaga cgttactgaa caatttaaat aagggcttcg gcccttaact aaggaaaatt 17940
atgttaggtt atcaagcacg agtaaaagaa gaatacgatc aattaatgct caaaattaat 18000
gcactgagca aatttttaga aagcacaaag tttctatcag ttaatgaagt tgagcaagaa 18060
ttactgcttt cacagttcat ctcaatgaaa tcttacgcag actgtttaga aaaaagaatt 18120
gcacaattca aataaataag gggcttcggc ccttttgttt taaggaaaaa ttatgattta 18180
ttgtatgaat atcggtgatt ccgacataaa agagattaaa ctgcacggaa atcatcacgc 18240
taatattgtg tactgcaata aatttgagtt tggtcacgaa aaacttgggt ttctttactg 18300
caatgatgtt atagtcatgg ataaaaagga actcgatgaa cttgaccatg agtctttaga 18360
tgaaaatgac cgaatttatt acggcactct taaagtatat aacgcttatc tcagcggtaa 18420
aaaggaaagt ctaaatgcag aaaacgaatc cgggtttaca gagactattt cagattccga 18480
catttaccct atcgaacagt gacttgacta gcgaaatgaa ggtcaaaatt gctgatacag 18540
caagatactc tttaaaacaa aatccaaatc aggataaagc agaagttatt gaaagatgtc 18600
gtatcgcggt gtacgcagaa ttttttgtag cagattggct aagtgggtat gttaacaaag 18660
gccaagaaga tgttaatgac ccgtatacat atgcatggga tgtattggcg catccaagat 18720
actgcgggct tcgtgtagaa gttaagacac atcaaactga ctcacgttgg atttctgtaa 18780
caacaggatg cagcggagag tatccatatg gttctggaat aaatctaggg cccattctga 18840
atcatcaggt cgctgactgt ataattatat tcaacactaa agaaattcac ccaggtgtca 18900
tccagtacac tccgaagttc atcggtgata gagaagacct tcgtaaggtt gtaagaaaaa 18960
gcaactacaa cggatggtat ctttccattt aaaaaaaatt ttcacaaaac ggtttacata 19020
ccacaaggac tgtggtacta tacaactatc aactgatacg gatttggaga ataaaatgtt 19080
tactacagct gaattaaaac gagcaaaagc taagaaaggg caaggaaaat ataaagctga 19140
attagttaaa gaacttcagt ttgctgaggc tgaattgaat tcaatgatta ttcaaaatgc 19200
tccagaaact gaaattgctc ttaaacgtat tgcgaataag tgtcttcatg atacaatcgt 19260
cgatctttta gcggattatt gagtaaaatg aaaatcgttg agattgaact atgagttcat 19320
tatggtggtg ttttgtttgg ttagttagta ttccattaat ttgtttaaca tttacttttg 19380
taatgaggtt attatgaaaa ttttgaattc tgtgcttatt gcttgtgcgt ggtgggttgc 19440
acaagtttca gcggtagtag ttggtattca catttattac gaatattttt aaaaaagttg 19500
tttacaagac tgttcctctg tggtattatt accctatcaa ctacggagga acagaaaatg 19560
aaaaagattg ttaaagctat atggaatgta gttataatac tagtagtttt gagtatattc 19620
ccaatcgttt taatgattga tgtattaaac gcttactttg gatttatgtg aggaaaatat 19680
gaagcgtaaa cgcagtgctt ttacatttat tgaatggttt ttcgataata tttttccggc 19740
tttattcatt ttcatgctga tttttgcctt aggttcagtt gtagttggaa tctatttgat 19800
ggcggtagtc ggaatggata ttcatcaaaa tggtttaaaa tccgtagttg aaacaatttg 19860
gaatggtgta aaatgatgaa tttactaaac atttggtttt atattcttat gttttacatt 19920
ggcgcaaatt tcccatattg gatgggatgg tcaacaactg catttggatt ttatactcct 19980
tgaggtgaat tatgaaaagt tttaaagatg taaaagttgg tgaaattttc tgtttagata 20040
atggtgatca gttaattcgt atttcacctc ttaagagcac tagcgagaaa ccgacagtta 20100
atgctacttt agcaaataat agtaatgaac gtttctgtat tgaaaatgat actgaaactt 20160
acaccgtaga agaattctgg gaattgagcg tcgactgcga cgattaattt aatggccgcg 20220
tgtattcatg cggccttgga gtagaaaata attagaggaa attaaaatga aatacatgac 20280
tgttactgat ctgaacaacg caggcgctac tgttattggt acaatcaagg gtggtgagtg 20340
gtttttggga actccgcata aagatatttt atctaaacct ggattttact ttttagtaaa 20400
tgaattcgat ggttcatgcg tatccgcacg attttatgtg ggtaatcagc gttctaagca 20460
aggattcagc gcagttctaa gtcatattcg tcaacgccgg tctcagcttg cgcgtactat 20520
tgcaaataac aatatggcat acactgtatt ttatcttcct gcttctaaga tgaaacctct 20580
gacgacggga tttggtaaag gtcagttagc tttggcgttt actcgtaatc atcattctga 20640
gtatcaaaca cttgaagaaa tgaaccgtat gttggctgat aactttaaat ttgttttgca 20700
ggcatattaa tgagtaattt ccataacgaa catgtgatgc agttttatcg taacaatctt 20760
aaaactaaag gcgtcttcgg acgccagtga ggaaaatatg aatatcgcaa aattattagg 20820
agttatttca tttatttgtt ggatagtagc atgtgtttta actatctgta ttgatgccag 20880
cagtgtgttt tcacaagctt tagcccaggg tatgtgtgca tatttaacat ttgtgttgtt 20940
atctactaat gattaagaaa atcttgggct attcactagc ccttgctact ttattggtag 21000
cactatatta tggagtaatg ttcggattaa ttcaagtcgt gcttttcatt tctgatgtta 21060
ttatggcact acattcacta gtatggtaaa tttatgcaac tgaataatcg cgatttaaaa 21120
agtatcattg ataatgaagc attggcttat gctatgtaca cggttgaaaa tcgtgctatc 21180
ccaaatatga ttgacggatt taagccagtc caacgatttg ttattgctcg agctcttgat 21240
ttggcacgag gaaataaaga taagtttcac aaacttgctt ctattgcagg tggtgtagct 21300
gaccttggat atcatcatgg tgaaaactct gcacaagatg caggtgcttt gatggctaac 21360
acttggaata ataattttcc tctgttagat ggtcaaggaa actttggttc tcgtaccgtc 21420
caaaaagcag cagcaagtcg ttatattttt gctcgtgtaa gtaaaaattt ctataacgta 21480
tataaagata ctgaatatgc tccggtacat caagataaag aacacattcc gcctgctttc 21540
tatttgccta ttattcctac tgttcttctt aatggcgttt ccggtattgc aactggttat 21600
gcaacttaca ttcttcctca tagcgtttct tctgttaaga aagctgtatt acaagctctt 21660
caaggaaaga aagtaactaa accgaaggta gaattcccag aatttcgtgg tgaagtcgtt 21720
gaaattgatg ggcaatatga aattcgtgga acatataagt ttacttcacg aactcaaatg 21780
catatcactg agattccgta taagtatgat cgtgaaactt atgtgagtaa aatcttagac 21840
ccgcttgaag ataaaggctt cattacgtgg gatgatgctt gtggtgagca tggctttggc 21900
tttaaagtta aattccgtaa agaatacgct ttgagcgata acgaagaaga acgtcacgcg 21960
aaaattatga aagacttcgg gttgattgag cgtcgttccc agaatattac tgttattaat 22020
gagaaaggaa agctgcaagt ttacgataac gtagttgatt taatcaaaga cttcgttgat 22080
gttcgtaaaa cttatgtcca aaaacgaatt aataacaaaa tcaaagaaac tgaatcagca 22140
tttcgtttag cctttgccaa ggcacatttc attaagaaag taatttcagg tgaaattgtt 22200
gtacaaggta aaactcgtaa agaactgacc gaagaacttt ctaaaattga tatgtattct 22260
tcttatgttg ataaactagt tggaatgaac atttttcata tgacttccga cgaagcaaag 22320
aaacttgctg aagaagctaa agctaaaaaa gaagaaaacg aatattggaa aactactgat 22380
gtagttacag aatacaccaa agatttagag gaaatcaaat gagtccattc ataggtatta 22440
caagcgctgc attagtatcc ggtagcattt tactggcggg tttaggtgtt gttccagccg 22500
tagcaggagg tcttcttgcg ttcggcattc aacgtgttat catgacagtt atcacagtca 22560
tgcagtaatt ttagggagag ccgaggctct ccctttttta tttcaaaaat tttttcacaa 22620
aacggtttac aaccaaagca tactgtggta ctatacaact atcaactact gatacagaat 22680
tacggagatt agaaaatgtc taaagtaact tacatcatca aagcttctaa cgatgttctg 22740
aatgaaaaaa ccgctgcgat tttaattacc attgctaaga aagatttcat tacagctgca 22800
gaagttcgtg aggtgcatcc agatttaggt aatgcagtag ttaatagtaa tattggggta 22860
ttgattaaaa aaggcctggt ggagaaatct ggtgatggat taatcattac aggcgaagct 22920
caggatatta tttcaaatgc agcaacttta tatgcgcagg aaaatgctcc tgaactactg 22980
aaaaaacgag caactcgtaa agctcgtgag attacttccg atatggaaga agataaagac 23040
ttcatgataa aacttttaga tgaaaatgga tttgttctta aaaaggttga aacttaccgc 23100
agtaactatc ttgctatttt agaaaaacgc actcacggaa ttcgtaattt tgaaattaac 23160
aacaatggaa atatgcgaat ttttggatac aaaatgatgg aacatcatat tcagaaattt 23220
actgacatcg gaatgtcatg taaaatcgct aaaaacggta atgtgtatct tgacattaaa 23280
cgctcagtag aaaacattga agcagtaatc actgtagcat ctgaactgtg aggaataaat 23340
aatgaacaag ttagaaattg ttaatgaact tcgtcgttgc gcagaaccta ctcaagaggg 23400
ttgggatatt tggtaccatg gagcttatct tggaactatc gtaaagatta agactggtaa 23460
atacatgatt attcgtgaaa gtaaagatgc tccagtaggt attcgcaata attttatggc 23520
agcgataagt tcatttacgg atgcagctta cgaaatttac cttgccgatt ataaagaatt 23580
ccaggaatct caaccggtta ttcgctcaat tggtgctaac aaagctcagc agaaaacttt 23640
gtggcaacgt attaaaggat ggtttaaatg aacccattta tcaatcgttt aaaaatgctg 23700
aatgttcctt tatctcgtga gactccagaa agtcttgttg aaaaatttaa agcgcatggt 23760
tataaatgca cagaagaaga tattctgaaa gaagttcctg aaatctgttg gcagactgca 23820
tattgggatg aaaaccaaaa gtatcaacga cgaattgtct gtgcagctaa tcgttttaaa 23880
ttaaaagatg gacgaactct tattattcca ggtgctcgtc attattctaa ggatatggca 23940
gaagttttag atgtagttaa acctcaatta gttactcaac aagtttgtga tgatgaccaa 24000
gggtttattg accaatatag taattattgg acacgtgaag aagcaatgat tattgcaact 24060
tacgctggac aagtacgtat tgaacgcggc ggtagtgaaa aagaacttta ctctgaggac 24120
ctttactaat gaatattaaa aagtttcaaa ttgatggaat tacgaatcaa atccaggcgc 24180
tggaatatgc caataaaatg atgtcaacta attggggaat ttatgccaat gaaccggcat 24240
ttcagttctg tgatatggaa ttcgctaaaa agctcgtagg aaaaaattat gtatgcccat 24300
ttagttctcc agtaaatgga atgctaaaac ccgctttacg cgatctttat attgcgatga 24360
acgaagaaat gataaaagaa ctaaaacgtc aactgaaggt gattcaattt gaccagggaa 24420
attaattcaa aatccgatta ttttaattct ctcaatgata aagataaaaa tttaatacgg 24480
cattttattg ttgagatggg atatactgac acacgtgatt taagagaaca tatatttgaa 24540
tgtggtgtag ctaaaaagtt ttcattcaca tgcaaatgtt tgagagaggt aattcagcac 24600
tatgaacaat ttagtcgcaa aacataattt taataaagct tctgtccata aggataagaa 24660
gaaagcgttt aaagaatcta atcgcaaaca gaaacataag gggaaggtct atgattattg 24720
attctcagtc tgtggttcaa tacacaatca aaattgatat tctagaaaag ctatataagt 24780
ttttaccaaa tttataccac tcaattgtta atgaattagt tgaagaactg catcttgaga 24840
ataatgattt cttggttgga acttataaag acctctcaaa agcaggatat ttttacgtaa 24900
ttccagctcc aggaaaaagt attgatgatg tattaaaaac tataatgatt tatgtccatg 24960
attatgaaat tgaagattat ttcgaatgag tcataatctt gaaaaggtaa tcgagcataa 25020
tgtagctcag gaacgtaagt cgttcaagga attcgtagaa aaaatttttg aagaaaatac 25080
cacagaccag tttacaaatc aagcgtctga tgatattata acaaagtcaa ctaattgagt 25140
ggtatagtta atgaataaaa atattgatac agttcgtgaa attattactg ttgcgtctat 25200
tttgattaaa ttttccagag aagatattgt tgagaatcgc gctaatttta ttgcatttct 25260
gaatgagatt ggagtaacgc atgaaggtag aaagttaaat cagaattcat tccgtaaaat 25320
tgtttctgaa ttaactcaag aagataagaa aaccctcatc gacgaattca acgagggttt 25380
tgagggtgta tatcgatatc tagagatgta tacaaacaaa taattattta gcccttccta 25440
atattctggc cgcctgagca catattgatt caaggcggtc attacttata tgatcatttc 25500
tataccagta catggttatt gttccagcat agatattatc caaattgaaa tatggacaac 25560
tgtacatgta atttatttcg ggagtaggct ttttagtcgg taaaaaagca aattttgagt 25620
tggaataata atgacgtcca tttaaatgaa ctgcatattc atccatagtt ttatcaacag 25680
gatatcctcc aagtgatttt tcacttatcg ttgaaggtaa ttttccttca tatgctataa 25740
tatcaacaaa atagtttaag tttttagggc ggaaagaata caccgcacta aagtctgcct 25800
cagatgatat atgaactatc tggagttgtt ccagggcgac agattcaaag cgtgcatttc 25860
tttccttttc aataatttca ctgtatgttt catactttga ttgcttatag tactcaaaga 25920
aactatctcc cctataccaa acaatcgcca ttataaacaa aagaattacg acagctaccc 25980
gggaagcaag aactttcccg gtagcgttat ctttgaacaa gcgatctaga acacccaaca 26040
gaatatcaga gggcgaaaat gatattctag gtgctgccat agaccctcct tttaaggata 26100
tttattcaaa ttatactctt ggaccatata ttgctccaac attttgccat gtcggtgtag 26160
accctatgac ggcataacca gcagcaccgc cgtcatattc tgtaccggta ccgtgagtat 26220
tacatctacc tcctgcggag ccaacttcac cgccattccc gcctgtatat gcactaagag 26280
acccctcacc gacagatcct gcacccggag cgtaaatagt gccgctggtt gcaccagcac 26340
tcatatgaga ggaagaccca ccagcgccaa atggacgacc gcctccgccg ccaaaggata 26400
gtctacccct gttgccgccg ccgccgccgc cgccgcctcc agcaatagct ccgccattat 26460
taattcttag tctcccacca atatcgtttt gaatacaatg acctccagct gaaccaggac 26520
tattgctacc gccattaccg ccacgtccat acatcgttac gccgtgtatg ttcagttgaa 26580
catattcatt cggtgtatct ccgtacatga agaataaagg aacatctcta gaatatgata 26640
ctaaatctcc agtgatatta aacactatag gtgcactacc tgcctcaaaa catctatctc 26700
ggaaccattg accgttgaag ttatggtctg ctccaagcgt gtgaattatt tcaacagatc 26760
gacctatcat attactcatc caaaatggag cacccattct taatcgttgg gccgcgccac 26820
ccatccaatt ttgtcctgta ttaactactg cagacgatcc tacccacggt cctgttactg 26880
ccatataaac ctccaagggg ccgaagcccc tcttattatt ttaacaatga tttaactaat 26940
gctttaagtt cttcgatttc tgatttaagt tctgcaattt ctgcggtatg ctcattgatt 27000
gcagctgtat ttaaaccaat tacaccgtta tagttcaaac gaagtaaagc ttcaccatca 27060
gggtcacctt caactaattc tggtaaaata gcttgaactt cttgagcaat taaaccggcg 27120
ttaggttccc atttctgatt accttcctca tccaggcctc gcttctgcat ataagtgtaa 27180
ccattaattt tggaaagctt ctcagaagca ttttcaaatt taacaaggtc ttttttaacg 27240
cgaatatcag aacggacata aacatcacgg acaaacgttg aataactatc atttgcctga 27300
acgagatgcc cataagaaac gatagctctt ccaacttctg tccaaaaagc accggttgaa 27360
tcccaaagcc caggatgaga ttgatagcct gcgccccagc ttgcaatatg tataccattg 27420
gcaaccatat tgattcggcc gtcactacca tgaactaatc cggtatcatt atcaccgata 27480
gcgatagatg ctccacccca taccggaatt gtgccgacgc ccaagttaac accagcgcga 27540
agtccagccg gagctttaaa atcaccattt atcccaaact catatattgc attaggatga 27600
ctgctatctc cgctttctgc ggaaccaacg cgaattactg catttcccca agtagcattt 27660
ccgcctaatc gaataatacc aaaatctgct tttgttgcat atccttcgtt aatgatttgg 27720
cttcttcctt taattatagg catatagcta tctttcggaa cagattcacc aaagtcaacg 27780
aagaatgggg cttctgtttg ccattgctga ttatatccgt gaccttgggt agctgtccac 27840
tgtcttccgt ttaaatataa acgataaaaa tttaatgaag ctgcagtagc ttgattttta 27900
acattaaagt caatatcgcc tacattatta agaataattc ctgccgtagt cttaaaatta 27960
taaaatgaag cagtgtcatc tgccccgcct ttaccgatgt accatgaatt cgctccacct 28020
gatgttccaa gtaaataagc agaatcattt tcatcggcag caatgttaat agcgtcagat 28080
cctcttttaa cgattaattt accagtcatc gtatcgcctt ctttagcaac acgagtagca 28140
atggcatcgc gaatattagt tacgtcgcct gctgaagtaa atgttttcca gatgtcagac 28200
cagatgttac cattgcgagc aatagtagct tcaccgccgc cgacagaaac gttatctggg 28260
aagttaacag taccgtcttg attaaaacga gacgtatggc cttgtgaacc atcttctttc 28320
agatgatgaa taacgaatgt acccgaatta atttcagtac ctaaagacca aacagcttta 28380
ccgtttaaaa acttctgctt aacaatagga taatatttgc ttatagcatc atcatcgatt 28440
tcctgaaaaa taggagctgc ttgaacatac tgaatatcat aaccgccagc accagcgccg 28500
tgaccgccga atttaatata accatttgcg gcaaaagaag cataacttaa atctaaatca 28560
ggaataacga ccttacctgt atctaaagcc atactaaatg ggcgaagtgg accgatatcg 28620
ccatttttgc cttcaccata agcggtcgga ataatgtgaa gactgccttc tgaacgtcta 28680
aaaatgactc cataatctgc attccaaatg cgaagcgcat tcacggcccc agatgaaatt 28740
tcacccgttg tgtgaactcc tctatttcca gcagtaacac cagatgattc aaatgaaccg 28800
ttaacgttca tttctacttc accggtagta agtctttgaa tatagctcat ccaactagtt 28860
gcatcagaaa tttccatgac atttttacga ttacctacac taggattagt aaacgtgtta 28920
ccccatacgg aaattgtcat attatcaact gaactactac cagttgtgtt acctctaaac 28980
atcaatgtag aagaattatt tctaccatcg atattaacag aaccaccaat aacatcaata 29040
ttaccaggag taactaataa tcctccagcg gtattaatat tagttgttcc tcttccacgg 29100
aaataatgat gatatctacc accttgataa tatcctaaaa gagtctgacc atctccaaac 29160
gcgttattat catgatatgt aacgacagta gcgagagcat agttttcagt aggaggagta 29220
gttaaatcgg ttccgttagt agaatatcca gctacaaatt ttcttaggct agttgtttcg 29280
ctaggactaa ataaaaatgt tttcgttcca ttattgacgc taaaataata tccatcctga 29340
taccatttaa atccagtatc attatctcca agagcaattg aagcagtccc taattcagaa 29400
tatcctttag agccacccgg aagacctata gaaatagaat gacctgcttt caatccaccg 29460
gaccaggtaa acgaccaaag ataggcctcc aacccgtcac cggcgtacca agttatcccg 29520
tcattatctt taacttcgtg gaatatacca gatcctactg catttcgcat aacacgaagg 29580
tggttaatag cagtttcgct ttctgccaat ggagtgttat ttgctaatga atagatgtca 29640
taatcgcctg tcttcttccc atctgtaata actttatcag tcaaaatctg aggagttgac 29700
atagatttcc atgctgatac ttcaggtgaa gtaaataggc cattgcctga aaatgcataa 29760
gtgctttcgc caccagcggc gtagtcatga accctgatat taagtacttg tgtagttaat 29820
ccatcattag ccggtgaata aatgattcca cgttcgcggc tattgctatc gaaaaaacga 29880
acatgtgatg tacctgaact ttttgtaata agttccccac cttcagtcat aatctgcccg 29940
gcggcaataa tatcgcgagt tactcgagca ataccgatta aattaaaatt acctgtctga 30000
gtgaaggtgc catttaaagt ataatcacca gtttgattat agtttcctat atgaataaca 30060
ttcccgtcaa tgctaccgcc tttagcaaaa cccagatcaa taatatttcc ttggtcatct 30120
ttagtaaaaa gtacacggtc ttttaagttt atagccaatt caccttcggc taatactgaa 30180
gcggcaggac gtgctcctgc ggttttgctt cttttaaatt gtatttgttt taaagtagcc 30240
ataagtcctc ttaataatag ccgaaatctt gaacagaatc cttaataaca atttgatcaa 30300
atcgtggaac atgtgatggt tgagatgcag gattctgcga aaaaaggttt ggcgcggtta 30360
agttacctgt catagtatct ccagagcgta ataccctaga gtttgcgttt gctgtaacaa 30420
tatttattgc tccatcgaca taatctttcc gcgtgaggtc ataattattt actggagata 30480
atgaagttgc gcgtatttgc gatgcttcaa ttacgccctt tgagctaata tctccatttc 30540
gtgtgttaat tactacagtt ctacctgctg ttccttgtga tgatttaaaa ccaataccat 30600
accacgaaac aatatccata tttgtagtat catacgtggc attatcacca ggaccagcaa 30660
aaataccgtt gtcacctgac cctgcgccag gaacagtcat tcctttatta aaaattactt 30720
tatttaaata cgtaccgcca ttagctttag aaacgaaatc gttatcggca gcttgtggct 30780
tattatattc tgaatatatt ttaaatgatt tatagagtac atcgtcaccg gctggattca 30840
atggaaaatt tccttgatgc caaatgacag agcctccagt tgttgaacct acttttaaat 30900
cagccattgt atgccccttt attttaatag tatttataaa gaaaaaggga acccgaaggc 30960
tccctcaatt taaacttctc taaattcttg tccaaacact ttaccagttt tagacgatgc 31020
ttgtgtagga agtaccatta tatccggagg tgaagcagat tcacagacat aattaactcg 31080
aataccattg acgccaaatt cagcaggttt tgaaattcct ccatttcttg atacttcaga 31140
aaagcttaaa tttctcatgc caccttgacc tgcttgcgca gttctttgtg catatatcgt 31200
aaatcctact gcattttctg gaataactac ataatcttcc tttaattccc atgacccagc 31260
ttgtccagta aactcagcat gtgttgaaga aatatatcca ttcgattcat cataaaaacg 31320
gatagatata tttgtagttc caagcgcaag taaatcggca tcagcatata gctgtgcttt 31380
aagataaaga acatcgccag gaattaaatt ataatcagag agtttactta tcgcggatga 31440
agttggtaaa cgtgcaattt cgttattagt tccaccaacc gctgacataa attgctcaac 31500
gctttcgtat gttcttttag gaaatcctgt agctccaacg tcttctaaac tatcaaatac 31560
aacatctaaa atagtttgat agtcatctgt gctttttcta ttacttagtt taacatgttc 31620
caatgcaata gctcttttag aagaagtata aaaggcagca tatgatacgt caaatcttga 31680
caatacagaa tcagatggaa aagcagacgt tcctgcggtt cttatccaag atactacctc 31740
aggaggaaaa ttaacttttc cgttagttaa tatagcaaca agtctattat tcgtcaaaga 31800
gttcatgaaa ctaacaaaag cagctgatgt agtatcattt gaagtcgaaa aagcatatga 31860
cttactatca actaatgctc ctgtagaagg gtcaaaaact cttaaatgaa gtcctgcgct 31920
aaatgtttga cttccaacag gattatcctg aaatttaacg tatggtcctt ctgcagtaga 31980
aagcgggcaa gaacccgcta tacttatttt atatcttact gaattgcttt ccgataaaaa 32040
tggcgtttgg acatatcctt gtccaaactc tgccataaat ttttccataa tacctcttat 32100
tcaacccatt caaatttaac cgttttattc actgggtcag gaataatgcg aacattacca 32160
attcgtaaga aatcacgaat agtaagattc cccattatag cattatcaga tggtaaagca 32220
ccgatatcag atggctgagg agggttacca ccatcaaata cctgaacaaa acttgaccaa 32280
gagtttttgg ttttctgcca tgtacgcgtc cagcgagtgg tgcgcgcttc tggggacgtt 32340
ggataagtaa tccaatcttg gtaaagtgaa tcgagtgtgt taccaaactg agtcaatgta 32400
ccaggagatt taacctcttc gccacgttct aagtatggaa gcccagtcac ttcattagtt 32460
ttttcaacca tttcaaaata acccgggaac tggttataag tggctgaatc attaatatcg 32520
attgaccaga atcctacagt atcagatgtt ggcgcacggg tatataaatc agaggtttta 32580
gtaccctgag aacgaattct cgagttaaca gtcaaaccac ctgaatttat agtagcacct 32640
ttggcaatga ttaagctttc accaatcgtt acttgaccag atgcattatt aatagttaat 32700
ggacgtaatc cattaaatcc accagtctga tcgcccgatg cagtaagcat aaaataggtg 32760
ttagcagcat cattacgaat aaagaatcca taatcaccgt ttattgctct aaaagcattc 32820
gacgatttac tgataaattc gccattagca gtaactgaac taccgaatgt tgcaacgcca 32880
ttcgcattca atgttcctga agcattcaca tttatcggtg ttactgtacc attgatatta 32940
aatgttatat taccagcttt attgcgctga gaataaaagt gactagacgt ttcatcacta 33000
acttcaaata cggtagaacg tgttgtgtcc gattcaccac tgaattgatt tccccacact 33060
ctgactgtca tcgtttgagc cggattcgtt ccagtttgag gtcctttctc aaaaatcaga 33120
cgagttgctg ttccagtatt agaaatggtt agtgtactat ttgctgaaac tgatccaccg 33180
aacgtagcag tactagatga tacaagaggg gcactcagat tcgtttgttg ggttaaggtt 33240
agtgaaccat taaccgtttg tgcaatatcc ctacgaatga actgagatga atctagacca 33300
tccagtaaat tactatctac agcttttgct tttaacggca aataatttgc taatacacgg 33360
tttaattcgt atggcgatac tgcataacta tttttctcgt acaattctaa tgactgtgtt 33420
gaaccaactg tatcattacc aacgaatgta attgaaccag atgaagtttt aacaaaacct 33480
cttaccagag tagtagctgc ccaagtaggt tcactctgca caatccattt taaatttttt 33540
ggagatacag cagtatttgc tgacgttcca gacacagttt cagactgcgt tgcaacttta 33600
ataacacctt cttgcgattc ggtagattta gtacctaaaa gctttttagg agttattaaa 33660
acattatcta atgttcctgc agcagcttca acttgtgtag ctacacgaag cgtaccacgc 33720
tgtgtctcat ttgcttcaag aatattaagg gtataatggt cccagagagt tcctgattca 33780
actaatccag atagagcaac aacagaagta cgatcagtac tatcaaatct agttttaatt 33840
tttaatggtg tagagatacg agtatcgtcg acgcctgcgt cgaattcaac ttgtgtagca 33900
atttcagcta taccacttaa actttcagtt gctttacggt catttaaagt tttaggagtg 33960
actgcacgag tataatcagt tcctgtatta acttcatttt gcgtagcaat ttcaattaaa 34020
ccaattcttg catcagttga tgtcttttta tgtaacgttt ctggtgttac aaccgcattt 34080
gcccatcctt cttggctttg tccagcaatt acttcacttt caactgctaa aattactgca 34140
ccttgttgcg ttggagtagc tttatactga tccaaagctt taggcgaaac aactaaatta 34200
ttagtgtttt tattataaac atttgtacca tttaattcac gactagaagc tggagtagct 34260
cctgcagtag atacaaaggt tacaatacca gataatgatt cagaaccttg tcgagcttga 34320
agctttttag gagtgatgat tgtagtatca tcagtacctg tattagtttc ttgctgtgtg 34380
gcaatttcag cgacacctct acgagtttct gtagcagttc tttcattcag ctttttagga 34440
gtgatgataa tatcgtcagc aaaagagaat gtagtatcct gattcacttg ggcggtagtt 34500
gctattcttg cgatacctct acgagtttct gtagcagtac ggttagctaa tgtttctggg 34560
gtaattgcta attctttttg tggagaattt tctaaatcga cgttagcttg agcttgtgta 34620
gctaaagcaa ttacgcctaa tcttgctcta gtagaattat ttaaagaatc gactctttca 34680
actgttggaa cgttttgctg tacaacccag tattttccgt cagaatcttc gatataagca 34740
agttgtaaaa ctggaacata attagtttca ccgttaaaaa ctaattcttg aacagtcacc 34800
cattcagctt caggtggata ttctgaacgt tttgggaatt gcagcaattg aactgaagaa 34860
gcaattttat cttcaccggc agctttgatt ttaactgttt ggccttttct catgtaattc 34920
atggaaattt taacagtatc accaatggaa atatcggttg gaagctgaag ttcaattgtt 34980
tgagttgttc cgttattcgc accaaatacc ataacttctt catttggacg aatactagaa 35040
ttagttgtta taatacgtaa acgtgcttta ctatccccgt caaacaatct ccacaatttt 35100
tcattatcat catacatcaa gaaaccgtca atcgatgtac gtccttcaat agaatgagtt 35160
ccatcttctt gtattgaagt agtttcgtcg tatgtagtaa caattgtatg ataaagtgga 35220
tttaatttat ctaaatcgac gaaattaata atatcgccat gattagcaaa tctcggaagt 35280
ttaatattaa tcggcgcagc ggaagtaaat ctgcgcacga taaaatcgtt agattgcgcc 35340
tgataaaaac ttgccggtgt tacaactaca gcttctctgc tataatcagc aacatacatt 35400
tgccacagac gattactaaa aattaaaact atctgtgatt ttggatgagt cattagtact 35460
gatcgtactt gctgacctct aaaatttaca atgctttgca ctggagctgt aattaaaact 35520
tggttaactc cgggttttcc accaatatct tgaagaacga tagtatctcc atcaattgga 35580
gaagttggca aagtaaatgt gatatcattt cctgctgcag tattaactga aattgattca 35640
cctgacttta attgataagg tcctgacgaa acagttgtcc agtttgcatc agtacgtaat 35700
gctctccagc gcacgctatt aaaagctcct gccggttttg gaatatcatt tatagcagcc 35760
caaaagcggt tatcataaat gattacaaaa tcttttaaat atccacgagt tggatcatat 35820
tgttgaactg tgttttcttg aattaggtaa tcaacgttaa caccgtcagt tcctacggca 35880
cgatcagcta aagctacgtt gattatttta tcgccacctg cgtccagacc atcttctgct 35940
ctgaactttc ttttaatctc ggccattctc ccgggctcct attgtgtttt caataataag 36000
tatttatact tgtttacttt aagatttgga tagtatataa tagaaatctc actaattgaa 36060
cgaggttcat atggatttag aaatgatgct ggatgaagat tacaaagaag gaatttgctt 36120
aattgacttt agtcagattg cgctttcaac cgctttagta aacttcccag ataaagaaaa 36180
aattaattta tcgatggttc gtcatttgat attgaactca attaagttta atgtcaaaaa 36240
agcaaaaact cttggataca ctaaaattgt actgtgtata gataacgcaa aatccggata 36300
ttggcgccgt gatttcgctt attattataa gaaaaaccgt ggaaaagcgc gagaagaatc 36360
tacttgggac tgggaaggtt attttgaatc cagccataaa gttatagatg aattaaaagc 36420
ttatatgcca tacattgtta tggatattga taagtatgaa gcagatgacc acattgctgt 36480
gcttgttaaa aagttctctt tagaaggaca caagatttta atcatttcat cggatggtga 36540
ctttactcaa cttcataagt atccaaatgt taagcagtgg tcaccgatgc acaagaaatg 36600
ggttaaaatt aaaagcggtt ctgctgaaat tgactgtatg actaaaatcc ttaaaggtga 36660
caaaaaggat aacgttgctt cagttaaagt acgatctgac ttttggttta ccagagttga 36720
aggtgaacga actccttcaa tgaaaacctc tattgttgaa gctattgcta atgaccgcga 36780
gcaagctaag gtgcttctca cagaatctga atataatcgt tataaagaaa atttagttct 36840
aattgatttt gattatattc ctgataatat tgcttcaaac attgtgaatt actataattc 36900
atataaatta ccaccgcgtg gcaaaattta ttcatatttt gtaaaagcgg gtctttctaa 36960
attaactaat agcattaatg aattttgagg tgaataatgg ctaaaaaaga aatggttgaa 37020
tttgatgaag ctatccatgg cgaagactta gctaaattta tcaaagaagc atctgatcat 37080
aaactgaaaa tttctggtta taatgaattg attaaagata ttcgaattcg cgccaaagat 37140
gaacttggcg ttgatggtaa gatgtttaat cgtcttttag ctttgtatca taaagataac 37200
cgtgatgtgt ttgaagctga aactgaagag gtagttgaac tttatgacac agttttctct 37260
aaatgatatt cgtccggtcg atgagaccgg tctttcagaa aaagaacttt caattaagaa 37320
agaaaaggat gaaattgcaa agcttcttga ccgtcaagaa aatggattta ttattgaaaa 37380
aatggtagaa gagtttggaa tgagttatct tgaagctaca acagcattct tggaagaaaa 37440
ttctattcct gaaactcaat ttgctaaatt tattccttcg ggtataattg aaaaaattca 37500
gtcagaagct attgacgaaa atcttttacg tccttctgtt gttcgttgtg aaaaaactaa 37560
tacattagat tttctactat gattaaactc cgcatgcctg ctggtggtga aagatatatt 37620
gatggtaaat cagtttataa attatactta atgataaaac aacatatgaa cggaaagtat 37680
gatgtaatta agtataattg gtgcatgcgg gtgtctgatg ccgcttatca aaagcgaagg 37740
gataagtatt ttttccagaa gttatcagaa aaatataaat taaaggaact tgctttaatc 37800
tttataagca atcttgttgc taaccaagat gcttggattg gtgacatctc tgacgctgat 37860
gcacttgtgt tttatcgtga atatatcgga cgcttaaagc aaattaaatt taagtttgaa 37920
gaagatattc gcaacattta ttattttagt aaaaaagttg aagtttctgc ttttaaagaa 37980
atctttgagt ataatccaaa agttcaatca agttatattt ttaaactact tcaatcgaat 38040
ataatttcgt ttgagacgtt tatcttgctt gattcgtttt taaatataat tgataaacat 38100
gatgaacaga ctgataattt agtctggaat aattattcta taaagttaaa ggcttataga 38160
aaaattttaa atattgattc acagaaagct aaaagtgttt tcattgaaac tgtgaaatct 38220
tgcaagtatt gatatgaata tagtatattg gtttacattt gaagaccgtg tcaaaaataa 38280
gactccacca tactactata tcggtagtaa attaaattgc tcatttgaga acggaataat 38340
atatgactct tccggaaagg aatactggag ctcatgtaaa caaaaaagat ttttgaatgc 38400
gctaatgctt caaaaaccga gcgttaaaat aattcaaatt gatgatgact tggatgttat 38460
tgaagcagaa cgaaaatacc aacttgaagt aaatgccaga gataatccag actattttaa 38520
tctggtatat gctggtggtg gatttggtgt gagtggtgaa actcatccag ccaaagaccc 38580
ggaagttaga gagcatatga gattggctaa ttatatgaac cgtgacgatt ttagaccttg 38640
gaaaacatca cgagctaata tagagtcttg gaaattatct catattgctt atgagaatta 38700
tgtgttatta ttatcctcta atctgtacgg taaaactcct ggatggcgaa gagttaaagg 38760
taatataaat ataactgata caactgctaa atcgatggta aagtatttca actcaggttg 38820
gatacctctc gaagacccag agtattgcaa attatgccag ctatgaggta aagtgtcata 38880
gcaccaactg ttaattaaat taagttaaaa aggaaataaa atgtttaaac gtaaatctac 38940
tgctgaactt gctgcgcaaa tggctaaact gaatggcaat aaaggttttt cttctgaaga 39000
taaaggcgag tggaaaccga aactcgataa tgcgggtaac ggtcaagcag taattcgttt 39060
tcttccgtct aaaaatgatg aacaagcacc attcgcaatt cttgtaaatc acggtttcaa 39120
gaaaaatggt aaatggtata ttgaaacatg ttcatctacc cacggtgatt acgattcttg 39180
tccagtatgt cagtacatca gtaaaaatga tttgtacaac actgacaata aagagtacag 39240
tcttgttaaa cgtaaaactt cttactgggc taacattctt gtagtaaaag acccagctgc 39300
tccagaaaat gaaggtaaag tatttaaata tcgtttcggt aagaaaatct gggataaaat 39360
caatgcaatg attgcagttg atgttgaaat gggtgaaact ccggttgatg taacttgtcc 39420
gtgggaaggt gctaactttg tactgaaagt taaacaagtt tctggattta gtaactacga 39480
tgaatctaaa ttcctgaatc aatctgcgat tccaaacatt gacgatgaat ctttccagaa 39540
agaactgttc gaacaaatgg ttgacctttc tgaaatgact tctaaagata aattcaaatc 39600
gtttgaagaa ctgaacacta agttcagtca agttatggga actgctgcta tgggtggtgc 39660
cgcagcaact gccgctaaga aagctgataa agttgctgat gatttggatg cattcaatgt 39720
tgatgacttc aaaacaaaaa ctgaagatga ttttatgagc tcaagctctg gcagttcatc 39780
tagtgctgat gacacggacc tggatgacct tttgaatgac ctttaataga ttatattact 39840
aattaattgg ggaccctaga ggtccccttt ttttatttca aaaatttttt cacaaaatgg 39900
tttacatccc tgttcttcta tggtactata caactatcgg caatactgct gacgattaaa 39960
gaggaaaaca atatggctaa agttgatatt gacatcgttg attttgaata tattgaagag 40020
attattcgta atcgttatcc tgaacttagt atcacaaatg tacaagattc taagttttgg 40080
agtattcaaa tcgttattga aggtcctctt gaagacctca cccgctttat ggctaatgaa 40140
tactgtgatg gcatggattc tgaagacgca gaattttaca tgggactgat cgaacaataa 40200
ttattaaggg gctatcaagc ccctattaaa atgaggaaac attatgtata ctggtagaaa 40260
gtatgaactt gttccaagac ttattgatac atttattaat tatagcccac gttctaattc 40320
atcaatagtt aaagctattc gagataatgg cggatggttt gaagttaaag aagtttccgt 40380
cgctaatgga tataaagcag taaaacacat tgaatgcgca aatggaaaac atttttacct 40440
caaagataga cttttagaaa tttgtgaaga cgaatttcat tgttttcgtg agtataaaga 40500
accgacttct gaagaagatg aagtcgaaga caagatttct ggcgtaacaa aaattcactg 40560
cattgttgac gaaaacaatg tagatgaaat cattgaactt ttgcgaaaaa ctttcaaaaa 40620
gtagtttaca gaagggtagt agtgtgatac tattacccta tcaattaagg agaataaaat 40680
gagattacaa cgccagagca tcaaagattc agaagttaga ggtaaatggt attttaatat 40740
catcggtaaa gattctgaac tcgttgaaaa agctgaacat cttttacgtg atatgggatg 40800
ggaagatgaa tgcgatggat gccctcttta tgaggatgga gaaagcgcag gattctggat 40860
ttatcattct gacgtcgatc agtttaaagc tgattggaaa attgtgaaaa agtctgtttg 40920
aggaaaataa tatgattttt gtatttgaat ttatgaatga tgaattcgat tatgcaattt 40980
ttaacgcatt gcataatcct gatttaaatg aatttaaaga aatgttttct gacgctttaa 41040
gtatgtcaga agaatactgt ggagaatgtc aacgtgtttg tgtgacagtt tttgaaaaca 41100
aagaaaagac atatgaagaa ttattctttg atgctaataa agccactgaa tggtttattg 41160
aaaggggggt tttgagtaat gattaaattg gtattcgctt attctccaac taaatcggtt 41220
gaaggcttta atgaattagc attcggttta ggtgatggtt taccatgggg acgagttaaa 41280
aaggaccttc agaattttaa agctcgtact gaaggtacaa ttatgattat gggtgctaaa 41340
acgttccagt cattgcctac attacttcca ggtcgtagtc atattgtggt atgtgacctt 41400
gcgcgtgatt atcctgtaac caaagatggt aatttagcac atttctatat tacttgggag 41460
caatatatag attacatttc tggcgacgaa attcaagtgt caatttctgg cgcgccattc 41520
gagactgtgc ttgatcagaa ttccaaagta agtgtaattg gaggacccgc tctactatat 41580
gctgcgttac cttatgcgga tgaagtagtt gtttctcgta tcgttaaaaa gcatcgtgtt 41640
aattcaacag ttcaattaga tgcaagtttt cttgatgata taagcaaacg tgaaatggtt 41700
gaaactcatt ggtataaaat agatgaagta acaaccctta cggaatcagt atataaatga 41760
gcaataaatt aaaagttaag gatgttccta atgctatggc cctttttatt tgtcggcaga 41820
tgcatcaagg gcctatgaca ccaaaacaat atcttaaagg tgagcgttct ttaggattta 41880
ctcgcaaagc aaaacaaatg gttaaattag gatataagcc taactttgcc aaatatcctt 41940
ctacatattc ttggatgaac taatgaaaca ataccaattt ttaattaaag atatcctgga 42000
aaacggttat gaaaccgatg accgaacagg cacaggaaca attgctttgt tcggtactaa 42060
attacgctgg gatttaacta aaggttttcc tgcagtaacg actaagaagc tcgcctggaa 42120
agcttgtatt gctgagctaa tatggttttt atcgggaagc acgaatgtca atgatttacg 42180
attaattcaa catgattcat taattcaagg caaaacagtc tgggatgaaa attacgaaaa 42240
tcaagcaaaa gatttaggat atcatagtgg tgaacttggt ccaatttatg gaaaacaatg 42300
gcgtgatttt ggtggtgtag accaaattgt agaagttatt gatcgtatta aaaaactgcc 42360
gaatgatagg agacaaattg tttctgcgtg gaatccagct gaacttaaat atatggcatt 42420
acctccttgt catatgtttt atcagtttaa tgtgcgtaat ggctatttgg atttgcagtg 42480
gtatcagcga tcagtagatg ttttcttggg ttaattgagg cctgagtata aggtgactta 42540
tacttgtaat ctatctaaac ggggaacctc tctagtagac aatcccgtgc taaattgtag 42600
gactgccctt taataaatac ttctatattt aaagaggtat ttatgaaaag tggaatttat 42660
cagattaaaa atactttaaa caataaagta tatgtaggaa gtgctaaaga ttttgaaaag 42720
agatggaaga ggcattttaa agatttagaa aaaggatgcc attcttctat aaaacttcaa 42780
aggtctttta acaaacatgg taatgtgttt gaatgctcta ttttggaaga aattccatat 42840
gagaaagatt tgattattga acgagaaaat ttttggatta aagagcttaa ttctaaaatt 42900
aatggataca atattgctga tgcaacgttt ggtgatacat attctgtaca tccattaaaa 42960
gaagaaatta ttaagaaacg ctctgaaact gttaaagcta agatgcttaa gcttggctct 43020
gatggtcgga aaactcttta cggtaaaccc ggaagcaaaa atgggcgttg gaatccagaa 43080
acccataagt tttgtgaatg tggtgttcgt atacaaactt ctgcttatac ttgtagtaaa 43140
tgcagaaatc gttcaggtga aaataattca ttctttaatc ataagcattc agacaaaact 43200
aaatctaaaa tatcagaaaa gatgaaaggt aaaaagccta gtaatattaa aaagatttca 43260
tgtgatggga ttatttttga atgtgcagcc gatgcggcta gacattttga aatttcatca 43320
ggattagtta cttatcgtgt aaaatctgat aaatggaatt ggttctacat aaatgcctaa 43380
cgactatccc tttagggagt agggtcaagt gactcgaaac gatagacaac ttgctttaac 43440
aagttggaga tatagtctga tctgcatggt gacatgcagc tggatataat tccggggtaa 43500
gattaacgac cttatctgaa cataatgcta ccgttcaaca ttgcatcata tgctgcgtta 43560
gttcatattg tagctaagat gtgtaatctt attccgggag atttgatatt ttccggtggt 43620
aatactcata tctatatgaa tcacgtagaa caatgtaaag aaattttacg tcgtgaacct 43680
atggatttat gcgaattgca attaaaattt ccagatgaat ttgatgaatg ggacacagaa 43740
tcgcaggtat tttggttgag tcaattcgca aagccgcata attttgttct taacaactat 43800
gaatcacacc ctcctattaa aggaaagatg gcggtgtaat tttaatttaa ttgcgaggat 43860
atatgatttt acgatttaaa gatacttctg gtgtagttct ttttacactt cctaatccaa 43920
gtgagttaga agttccagga ccagaacaac ctattatcat ttatggtaaa aagtattata 43980
ctcataaaat gactcgtgag tattttgata ataaaatttc cacagttaaa acttcttctg 44040
attgttatta tgatattact gttttaacgg aaaaacaata tgaagaatgt agaactttag 44100
cagtataaat atgattccca acaatctaga gcacatcttt tagatataag ttttctgctt 44160
attccggttt gacgcacagc ttctgctatt gttggatatt ctaccccatc tatacttact 44220
cttagatggg gtttcttttt acctctttgt gagtcagaaa ttcgttttct aacttcattg 44280
gtatgtgtct gtccataata tggattattg atgcctttca tattaagcgc agcgtttctt 44340
tcttggaact ttttgcttag ttctatagca cgatctaacc catagtgttc ttctatagtt 44400
ttacctttga tatctttagg tctaccatgt ttttgcttaa gttcttctgg tgataatttt 44460
gaattattat ttttaattgc atttgaaatt ttattaagga tttcttgctt tcttgggtga 44520
tgagataagg tatccccaaa cgatgcgtct gctatattat acccattttc ctttgagtca 44580
tattcatgta tccaataatt ttcacgttca ataatgatag atttttcgta tggaagttct 44640
tctatgattt tacatacgaa agcatctttc ccatgcttat tataagaacg ctgcagcttt 44700
attgaatgat gatttccatt atctaaatct ttaaagtgtc gtttccatcg ttcttcaaaa 44760
ttaattgcac ttcctatata gtgcttattg gttttagtgt ttataatagc atatattcca 44820
gatttcatta tattctccta tataaaatta tatttatatg gggtaactta ctacagagga 44880
cttatgcaat taattaatgt tatcaaaagt agtggtgttt ctcagagctt tgacccgcaa 44940
aaaattatta aagttttatc ttgggcagct gaaggaacat ctgtagatcc ttatgaatta 45000
tatgaaaata ttaaatcata tctccgtgat ggaatgacaa ctgatgacat tcaaactatt 45060
gtaattaagg ctgctgcgaa ttctatttca gttgaagagc ctgattacca atatgtagct 45120
gcacgctgtt taatgttcgc tcttcgtaag catgtttatg ggcagtatga accacgttca 45180
tttattgacc atatttctta ctgtgtaaat gaaggtaaat atgaccctga attgttgtca 45240
aaatattcag cagaagaaat tacattttta gaatcaaaaa ttaagcacga acgggatatg 45300
gaatttactt attccggggc gatgcaatta aaagaaaaat atctagttaa agataaaacc 45360
actggtcaaa tttatgaaac tccacagttt gcatttatga ctattggaat ggcactgcat 45420
caagatgaac ctgttgatag attaaaacat gttatccgtt tttatgaagc agtatctact 45480
cgacagattt cattgccaac tcctattatg gctggttgtc gtactcctac tcgacagttc 45540
agttcatgcg ttgttattga ggcaggagat tcattgaagt ctatcaataa ggcttccgct 45600
tcaattgttg aatatatctc taaacgcgct ggaattggta ttaacgttgg tatgattcgt 45660
gccgaaggtt ctaagattgg catgggtgaa gtacgccata ctggtgttat tcctttttgg 45720
aaacattttc agactgctgt taaatcatgc tcacagggtg gaattcgtgg cggcgctgct 45780
actgcttatt atcctatttg gcatttggaa gttgaaaatc ttctcgtttt gaaaaataac 45840
aaaggtgtag aagaaaaccg tatccgtcat atggattatg gcgttcaact gaatgaccta 45900
atgatggaac gattcggaaa gaatgattac attactttgt tcagtccgca tgaaatgggt 45960
ggcgaacttt actattctta ttttaaagac caagaccgtt tccgtgaatt atacgaagct 46020
gcagaaaaag accctaatat tcgtaaaaag cgtattaaag cccgtgaact gtttgaattg 46080
ctcatgactg aacgctcagg aacagcaagg atttatgtgc agttcattga taatacgaat 46140
aactatactc catttattcg tgaaaaggca cctattcgtc agagtaactt gtgctgtgaa 46200
attgctattc caacaaatga tgtgaatagc caacaaaccc gtttaatcaa aattaagaag 46260
tcggatgtag ctaagtttta tgaagctaat cctggcggta taattcaaag caaataaagt 46320
acacagaccg ttaataaata atccataaca agaggaaaag ttatggatta ttctaaaatt 46380
tacaataacc ttatttctaa agctaagaac agaaaattag attgctatac cgaatcacac 46440
catattatac ctctgtgtat tggtggttct gatacaaagg aaaacctggt agatttgaca 46500
cccgaagagc attacatagc tcatcaatta ttagtaaaga tatatccaga taatcataaa 46560
ttggtatttg ccgctaatat gatgtgtgtt tattctgaag ataatattga acgaaagaac 46620
accaataaac gccatgggtg gcttagaaga aaattggcta tttctgtatc tgaaaataat 46680
aaaggcaaac cagcttggaa caaaggtatt ccggtaactg acgagcatag agaaaaactt 46740
caaacaactt gggtatttac tttcccggac ggtcatgaag aaatccataa aggcctaaga 46800
gaattttgcg aactacattc actcaatgct tcggcaatgt cggccgtatg caaaggcaaa 46860
aggtctcaac ataaaggctt taagtgtcga aagcttgata atatctctga aaacgataat 46920
caagaatacg tcagtaaacc tcatccaaag ggattaaaac cccataactt aattgctgta 46980
aaaataaacg gtatagaata tcaatcaata catcgagcat ctaaagctct aggaatatct 47040
cgaaaaaagg tagaagaatt aaatgaatat tgattatgaa tttgtagatg aattttacga 47100
agatgatgag tatacaacaa tacaagttat tgaaaacaaa ggtgaagtgg gcctctgcac 47160
tctctctgca ttcgtactag ataattttga ctggcaagac caagataaaa ttaatgaatt 47220
ggcagaagtc caagttcgtg ctcttgataa tcttttggac taccaaggat atccagttcc 47280
tgaagcagaa aaagctaaaa agcgtcgaaa ccttggcgta ggtgttacta actatgcagc 47340
ttggctggca agtaattttg cttcttatga agatgctaac gatttaacac atgaactatt 47400
tgagagatta cagtatggac tcattaaagc atccattaag ctcgccaaag aaaaaggacc 47460
ttgcgaatat tattcagaca ctcgttggtc tcgaggcgaa ttacctatcg actggtacaa 47520
taaaaagatt gaccaaatcg cagctccaaa atacgtttgt gactggtcgg cgctgcggga 47580
agaccttaag ctctttggca tccgtaatag cacattatca gcacttatgc catgtgagtc 47640
atcttcccaa gtttctaaca gtacaaacgg tatcgagcct ccacgtggac cagtctctgt 47700
taaagaatca aaagagggtt cctttaatca agtcgtgccc aatattgaac ataacataga 47760
cctatatgat tatacgtgga aattagctaa gaaaggtaat aaaccttatc ttacgcaggt 47820
agctattatg ctgaaatggg tatgtcaatc agcttcagcg aatacatatt atgacccgca 47880
gatttttcca aaaggaaagg ttccaatgtc tgtaatgatt gatgacatgc tatacggatg 47940
gtattatggc attaaaaact tctattatca taatactcgt gatggttccg gtactgatga 48000
ttacgaaata gaaactccaa aagctgaaga ttgttcatcc tgtaaattat gatataattt 48060
gactcacgga cgagtcacta tctattaact aagcggaaaa tttatgagca cagtttttaa 48120
tacaaatcca gttgatgttt taaaagaacc tatgttcttc ggttcaggtc ttggtattgc 48180
gcgttatgat attcaacgtc ataaagtttt tgaagattta accgaaaagc aattatcatt 48240
tttctggcgt cctgaagaag taaacttgat gatggatgct gcacaattta acaagcttcc 48300
tcagtatcag caagatattt ttactaataa cctgaagtat caatcacttc tagatagcat 48360
tcagggtcgt gcaccatctg ctgtacttat gtcattaatt tcagatccaa gccttgatac 48420
atgggttgct acatggactt ttagtgaaac tattcacagt cgttcatata ctcatatcat 48480
gcgaaatctt tatactgatc cgtcaaaggt atttgatgag attgtattag atgaagctat 48540
catgaaacgt gccgagtcca ttggtcgcta ttatgatgat gttctgatta aaacccgtga 48600
atgggaaaat gctaaagaat ttgtagaact agctaaagaa tctcctgatg ccgactttcg 48660
tttaaaccga gctattaaac aagaagccga agctaaacgt gctttaatga agtctcttta 48720
cctctgttta cacgttatta atgcattgga agctattcgt ttttatgtat ctttcgcgta 48780
aaatgcgcct ttaagcagta atgcttattg aaaactcctt taattgctgg aaaatccaga 48840
aatggaaaac tagcagccaa ggttttgctt gcacctttaa ttagtataat attataaata 48900
tgattatact tttaagagga tgcacaattg aattatagaa aaatttggat agatgctaac 48960
ggaccgatac ctaaagattc tgatggaaga acgtatgaaa tccatcataa agatggtaac 49020
cgtgaaaata atgatttaga taatttgatg tgtctttcta tacaggaaca ttatgatata 49080
catttagctc aaaaagatta ccaggcatgt cacgctataa agcttagaat gaaatattct 49140
cctgaagaaa tttctgaatt agcttctaaa gctgcaaaat ctagagaaat ccaggttttt 49200
aatatccctg aagtgagagc taaaaatatt gcctctatta aatctaagat agaaaacggt 49260
acatttcatc ttttaagtgg tgaaatacaa cgtaaatcta atttaaatcg ggttgcatta 49320
ggtatacata attttcaaca agctgagcat attacaaaag ttaaagaacg taatattgca 49380
gctataaaag aaggtactca tgcattttgc ggtggtaaaa tgcagtcaga aactcagtca 49440
aaacgagtaa atgacggttc acatcatttc ttatcagaag accataagaa aagaacatca 49500
gcaaaaacat tagaaatggt taagaacggg acccatcctg cacaaaaaga aatcacatgt 49560
gatttctgtg gtcacattgg taaaggtcct ggattttatc taaaacataa tgacagatgt 49620
aaattaaatc caaatagaat tcaattgaat tgtccatatt gtgataagaa agatttatca 49680
ccatcaacat ataaacgatg gcacggcgac aattgcaaaa caaggttcaa cgactagtct 49740
ttggacgtag ggtcaagcga ctcgaaatgg ggagaatccc tccgggattg tgatatagtc 49800
tggactgcat ggtaacatgc agcagttcat aagagaacgg gttgagaatt agcgagctca 49860
atcgaacata cggtactttt aacttccata agaacatgga aatcatggaa ggtaatgcca 49920
agattatgaa gttcattgca cgtgatgagc agcttcacct taaaggcacc caatatatta 49980
ttcgtcagct tcaatccggt actgatggtg atgaatgggt taaaattgct caagagtgtg 50040
aacaagaagc agttgatatt ttcatggaag ttaaccgtca agaaaaagac tgggcagttc 50100
atttatttaa agatggtgat gttcctggat taaatacaaa tagcatgtgg agctttattg 50160
attacttaac tgtatctcgt atgaaacagt gtggtcttcc atgcccaatt accgatgctc 50220
cggttaaaca tccgtatcct tggattcgtg aatatcttaa ttctgataat gttcaatccg 50280
cgccacaaga agtagaactg tcatcttacc ttgttgcaca gattgataat gatgttgatg 50340
ataaagttat gatgagtttt aaaaaatatt tttaaggagt gggccgcaag gcccatttta 50400
ttatgaaaga aattgcaaca gaatattcat ttattaaata tactgagcta gaattagacg 50460
acaatggaag tataaaacag ttatctattc caaacaagta taacgtaatt tatgctattg 50520
tcataaatga tgagcttgtt tatattggaa aaactaaaaa tttacgtaaa agaataaact 50580
attatagaac tgctattaac cgtaaagaca aaacgtctga ttctactaaa tctgcattaa 50640
ttcatgctgc gctaaaggaa ggaagcaaag ttgaatttta cgcccgccaa tgttttaatc 50700
tttctatgac aaatgagtta ggtacaatga caatcgcaac gattgaccta gaggagccac 50760
tattcattaa actgtttaac ccgccttgga atattcaaca caagaaaaaa tgatgcttcc 50820
acatggagtg tggtactata ttcaaaacac aaaagaggat acacaatgca agaacttttt 50880
aacaatttaa tggaactatg taaggactca cagcgtaagt ttttttactc ggatgatgta 50940
agtgcatctg gaagaactta cagaattttc tcatataatt acgcatctta ttctgattgg 51000
ttacttccag acgcattaga atgtcgtgga attatgtttg aaatggatgg agaaaaaccg 51060
gtaagaatcg cttctcgtcc tatggaaaag ttttttaact tgaatgaaaa tccattcacg 51120
atgaatatcg atttaaatga tgttgattac attctaacaa aagaagatgg gtctttggta 51180
tcaacatatt tagatggtga tgaaattctg ttcaaatcaa agggttcaat caaatccgaa 51240
caggctttaa tggctaatgg gattttgatg aatattaatc atcatcagtt gcgcgacaga 51300
cttaaaaaat tagccgaaga tggatttact gctaactttg aattcgttgc tccgacgaat 51360
agaatcgttc ttgcttatca agagatgaaa atcattttat tgaatattcg tgaaaatgaa 51420
acaggcgaat acatttcata tgatgacatt tataaagatg ctgctcttcg tccatatcta 51480
gttgaacgat acgaaattga tagtcctaaa tgggttgaag aagctaaaaa tgcagaaaac 51540
atcgaaggct atgttgctgt gatgaaagat ggttctcatt ttaaaattaa gtctgactgg 51600
tatgtatctc ttcatagtac aaaaagttcg ttagataatc cagaaaaatt gtttaagact 51660
attattgatg gtgcatcaga cgatcttaaa gcaatgtatg ctgatgatga atactcatat 51720
agaaaaattg aagcatttga aacgacttat ctgaagtact tagaccgagc tctgttttta 51780
gttcttgact gtcacaataa gcattgcggt aaagatagaa agacttacgc gatggaagcg 51840
caaggcgttg ctaaaggagc tggaatggaa catctgttcg gtatcatcat gagcctctat 51900
caagggtatg atagtcaaga gaaggtcatg tgtgaaatcg aacagaattt tttgaaaaat 51960
tataaaaaat ttatcccaga aggatactaa gctgtttaca agtccctcgt gttgtgttac 52020
agtagtctta ctgacataac atgaggactt tatgatggat ttgcagctta ttactactga 52080
gatggtcgtt gaagcatacg gtgatactac agatgggatt tctgtattta aaggaaatcg 52140
tcgagttgga tatatcaccg atcttaagaa agatttagct aagcaagtca agcggaaaac 52200
gaccattaaa gaatatcgaa atcgtcgtct tgagcaagct cgtgatatgc ttcctgatgc 52260
ggttgaggag atgaaagtct ttttagaaaa tcagcttgcg aaatatgatt gtgatgtatt 52320
cattaatcag actcaaccta atgttcatat taacaactgt aaatgctata tcatcgttaa 52380
tcctttaacg ggaaaacatc gtcttggaat tagtaatcca aatcgtagcg catcagatat 52440
ggcagaagat gttgaggcat gctttaaaat ttctaaatct ccggctgaac atcatatttt 52500
aattaacggt ctttctcaag acgatattat agaggttatt aaaactttat gcaattaagt 52560
aatacgacag caggtttgtt attaattgta attgcattgg gcggaacttc tttaatttta 52620
aaaagtaaaa ttgaaagatt agaaacgtct gttgtagaaa ttacaaaaac ggccaatgaa 52680
aacgctttag cattaaatga tttaaaaatt caatataatt atattgatgc gatgaataat 52740
aaaaatcgtg aggcaattgc tgctattgag cgtgaaaatg aaaaactgcg caaagacgca 52800
aagaaggcgg atgtggtggc tcataagcca ggattggttg aaaaacaaat caacaactcc 52860
tttaataagt tcgcagaaga catccaggac ctttctaaat gattaaacta tcagcagtaa 52920
tattatctat tggtcttcta gttggttgtt cgacaaagcc tctagaagta aagaaagaaa 52980
cagttcatcc taattggcct gtgcagataa agtcatatga tgaagctaaa ctatcctggc 53040
aagttaaagt tatcgatggt aaagcttggg tcggtatgcc atttgaagat tcccaggaat 53100
ttcgtatttg gcttaatgat gtaaaacgat atgtgcatga ccagaaaact atgatatgtt 53160
attatcgtca agagttaaaa gaggataaat gtaaatgatt tcatggcatc aatttgaaca 53220
tctcaaaggg ttgatttatg aatccgagat ggctgcaatg atttacggac gccagattca 53280
acgattagaa tctttgcctc caactaatga tgttttatta gctcaatctc gggctaatct 53340
taaaaatgaa tatcaaaata agtggggtaa agcatctaaa gacctgcatg attatattca 53400
atcattagtt gagaaaaata aatgaaaact ctgctagaac gttatattga atgctcagat 53460
cgttacattg atgcatgcca tggtgcagta tacatggatt tggaccgcgg aatagtatta 53520
aatgatgaag accctgcgaa agctttagat gatgctggta aagctctacg aaaagaagca 53580
aaagctcgtg gacttgatat gtatcagctt aaaaatcaca tgataaaatt tatttcatct 53640
aatgttcaga gcaaatcggt gaatcaatta acagctgaat tatataaaga gcggcgtgag 53700
cataatattc gtattcttga agttttctta ggaattaaat gatgaaaaag attattttga 53760
ctgttggatg tcctggttca ggtaagagca cttgggctcg tgaatttatt gctaaaaatc 53820
ctgggtttta taatatcaat cgtgatgatt atcgtcaatc catcatgggt catgaagaac 53880
gtgacgagta taagtatacc aaaaagaaag aaggtatcgt aactggtatg caatttgata 53940
cagctaaaag tattctgtac ggcggtgatt ctgttaaggg agtaatcatt tcagatacta 54000
acctgaatcc cgaacgtcgc ctggcatggg aaacttttgc caaagaatac ggctggaaag 54060
ttgaatataa agtgtttgat gttccttgga ctgaattggt taaacgtaac tcaaaacgtg 54120
gaactaaagc agtaccgatt gatgttttac gctcaatgta taaaagcatg cgagagtatc 54180
tcggtcttcc ggtatacaaa gggactcctg gtaaaccaaa agcagttatt tttgatgttg 54240
atggcacatt agcaaaaatg aatggtcgcg gtccttatga ccttgaaaaa tgtgatactg 54300
atgttgtcaa tcctatggtt attgaactag ctaagatgta cgataagcaa ggatattaca 54360
tcgtagtcgt ttcaggccgt gaaagtggaa ccgaagaaga cccaacgaaa tattatcgta 54420
tgacccgtaa atgggttgag gatattgctg gcgttccatt agttatgcaa tgtcaacgcg 54480
aacaaggtga tacccgtaaa gatgatgtag ttaaagaaga aattttctgg aaacacatcg 54540
caccgcattt tgatgtgaaa ttagctattg atgaccgtaa ccaagtcgtt gagatgtggc 54600
gtcgtatcgg tgttgaatgc tggcaagttg cttatggaga tttttaatgg cgtggcatca 54660
tgaaacttgg tctattgtta ttgtaaatag tggtttagtt ggtactagta atgggcaatt 54720
ttgtgtattc actagtgaaa tcagagcttg ggaggaatgc cttaaattaa gagaaaagaa 54780
tcctgatgtt gaactaacag taaagaaaac taaactgcct ttaccatgga aaacttatga 54840
ataacataga aaagatttat caactttgcg ataaaattga aaaagaaaag aaatatctat 54900
tttgtttatg gcctattgtt gatggaagaa tagacttaga tattcttgat tatgaaacag 54960
aagacatagt agatggttca acttttgata atgcgttgga tgttattaat tggcttgaag 55020
aaaattatgt gaggtaaata tgtttccgac ttattctaaa atcgtagaaa tagtgtttag 55080
ccaaattatc gctaataata tgtttgaaaa gcttgataac gcagctgagc ttcgaattca 55140
tgctcaagtg actcatgtat tgaacacttt gcttccagac caggtggatt ctattgcaat 55200
tacgctgtat ccgggttccg cgcatatcat tgtcgtattt ggtcttgatg ctgagctagt 55260
catcaaaggc gatattcgct ttgaatcaca gacatcagaa ttcaaggcaa tttaatagtt 55320
tactttttgg tagagttgtg atattatagc tctaccaaaa caaatgagga aaacaaaatg 55380
ctaagtgaaa aaccaattac tgttaaagaa ttccaagaaa aagttaaact atttgcacag 55440
gaattggtaa ataaggtttc tgaacgattt ccagaaacat cggttcgtgt tattaccgaa 55500
actcctcgtt cagtattagt aattgtgaat ccaggtgatg gcgatcaaat atcgcatctt 55560
aaactggatt ttgatggatt agttgaagca caaagggtgt atggcgtact atgatgaatt 55620
taactgatat aattgataat tgtcttgaaa atgatactgg cgatcataga gcgcttgatt 55680
ctgaaacagc acagttcatt agaataactt taatgaacga tactctggtg aatagtattc 55740
atccttctgt gtatgatgct attattgtga cgaagtatcc agttgagctt cacaaaaaga 55800
tggctggtgc aattttcatt gataagaaaa accgctttaa agatgggcag aatataatta 55860
gttctgttat taaaagtata actaaacttc gtcacgaaat ttatcgtgtt gaaactgcta 55920
aatctgctta tctggtgatt atgaaatgaa agcgagtaca gtacttcaaa ttgcatattt 55980
agtatcacaa gaatcaaaat gttgctcctg gaaggtagga gcagtaattg aaaagaatgg 56040
acgtattatt tctactgggt ataatggttc gcctgcaggt ggtgtgaatt gctgtgatta 56100
tgctgctgag caaggttggt tgctgaataa gcttaaacat actatcattc aaggtcataa 56160
gcccgaatgt gtatcatttg gttcaactga tcgttttgtc ttagcgaaag aacatcgtag 56220
tgctcactct gaatggtcgt ctaaaaatga aattcatgct gaactaaatg caattttgtt 56280
tgctgcacga aacggttctt caattgaagg tgctactatg tatgtaacac tttctccttg 56340
tccggattgt gcaaaagcga tagctcaatc tggtattaaa aagctggttt attgtgaaac 56400
atatgataaa aataaacctg gctgggatga tattctgcga aatgcaggta ttgaagtgtt 56460
taatgttcct aagaaaaact tgaataagtt aaactgggaa aatatcaacg aattctgtgg 56520
tgaataatga aatttcgttt ggtacaactc acagcaatta gttcttattc caacgagaac 56580
atttcatttg ctgtagagta taagaagtat tttttctcta aatggaagca gtattataag 56640
tcaaactggg tttgtattga taggccgtat agttggaaat ctgatttaga aaaatgccaa 56700
aagttgcttt ccactcttaa agaacgtgga acaactcata ttaaaactgt aataggtaaa 56760
taaatgaaat tgacgactga acaaaaagta gcaattcgtg aaattttgaa aactaaattg 56820
tccatgggta tttcaaacgt agtttttgaa aagtctgatg gtactattcg tactatgaaa 56880
ggtactcgtg atgccgattt tatgccaacc atgcaaactg gtaaattgac tgaatctgcc 56940
cggaaagaat ctactgatat gattccagta tttgatgttg agcttggcga gtggcgaggt 57000
ttttctatta acaaattgat ttccgttaat ggtatgaaag ttgagcattt gcttcaattt 57060
attggtaaat aaatgcttta agaattattt gttattatta attcatctgt taacaaaaag 57120
gaaaaacgat gtctgaagta caacagctac caattcgtgc tgtcggtgaa tatgttattt 57180
tagtttctga acctgcacaa gccggtgatg aagaagttac agaatcagga cttattatcg 57240
gtaaacgtgt tcaaggtgaa gttcctgaac tgtgtgtagt tcactctgtt ggtcctgatg 57300
ttcctgaagg tttctgcgaa gttggtgatt tgacttctct tccagttggt caaattcgaa 57360
acgttccgca tccttttgta gctctgggtc ttaagcagcc aaaagaaatt aagcaaaaat 57420
tcgttacctg tcactataaa gctattccgt gtctttataa gtgatataaa taataatacg 57480
aattgggtgt cggaataata agttaaccga acaattctat gtggtagtct acaactgaga 57540
gatctgtcga aagaagatga aattcagaag aacgtgacta ccgagtttta atctctaacg 57600
agaattttta aatgattaaa caattacaac acgctcttga actgcaacga aacgcatgga 57660
ataatggtca cgaaaactat ggcgcatcta ttgatgttga agccgaagct cttgaaatcc 57720
tgcgttattt caaacatctg aatcctgctc aaactgcatt agctgctgag cttcaggaaa 57780
aagatgaact taagtatgct aagcctttgg cttctgctgc acgaaaagca gttcgtcact 57840
ttgtggtaac actgaagtaa ttatgccgtg gttggtagtt atcctggcgt taacgatgta 57900
aaactaccaa atttcagtta gtatcgagga gccgtcgaac tgtctgatta atgatttgcg 57960
aatcattata gttttaagac cccggcagtt ttacggtgta cctcttgaat gttattctta 58020
tagcggcaag tgcatgctac cccgaggtga tggccaatcg ggagtacgcc tcaaggccta 58080
tatatccatc agtatatatc ttatcctcga gaaatcgaac ccggaacctt taagctaacg 58140
gtgtgcaaca gataagagct ataaggtatg atgacgggtt tatggttatc ctggtcgtta 58200
aatatccaaa aacctatgtt ccccttgagg gcttgcgcag gcaatgccaa taagtcctgc 58260
attttcattt aaaagagaat ttataatggc aaaacaagct aaagcaaaga aagcagttga 58320
aaagaaagtt ggtgattcta aacgcgctgg ttacaagcgt gggtcgaact ctcgtatcaa 58380
tcaaactgtt gagaagatca tgcgccgagc acgtgcggtt cttcgagatg atgcttctcg 58440
ttttggtaag cagaaagcat aagttgagga ctccttcggg agtccttttt tattttccaa 58500
agattgcata aagttgttta cagtatggtt cctttgtgat agtattatct tacacaaaca 58560
aaggagaata aaatgaaaac gattaatctg aacgctgcag ttaaaactaa atgcttcaat 58620
ggtaaatatg atgaaactat gtggttctta atggcagttg aaggtgatat tattgaagta 58680
gaaacaacag aaggtatggg aacagatttc acctttacaa ttcaagttca taatttcttt 58740
actggttgga tttatgaatt gaatacagta atcgttggaa aaattgaaca aaatgaatta 58800
ggtgaatggt attatgttac agctcgccaa cgtgccgaac gcttaattga gaagatgaaa 58860
aaagttggta aacttgatat gcagcattgg aaagtagtaa aataattgtt tactttggta 58920
caggatatga tattatatac ctgtaccgca attaaacatc ttggagaata aaatgaacta 58980
catcaacttt gaacgtaaat atgtttctaa tggtattgca ggttctattg atactatttg 59040
cctttggaaa catcaaaatg gatcagtatg cgaaattgaa cagtatatga ctcctaacta 59100
cgtttatatg cgatttgaaa acggtatcac ggtttcaatc acaatggaag gttccaactt 59160
caaaatcgct ctggatgatg atttccgtga acgcgattta gggactcatc cttgctggaa 59220
tggcgttaat cgcaagcttt tggttaaaac ttggattcgt catattctga gtaacagagc 59280
taaacctgag catcttgaag caatctttga tgtagttctt aacgaatttg atatttaaaa 59340
taaatgaggg gctttggccc cttactgagg aaaatgttat gtttatgact acttattttg 59400
atacccgtaa aaacttctgc gaagtagttt tctcaaaggc gcctaaagac cttcctgcac 59460
atttgcaacc taccagtgaa tcgattaaaa actacgttaa tgtagtctgc cctttagagt 59520
tccgtactgt aaatgggcgc gatactttag ctatcactaa actcaatcgc gaaattgaca 59580
ttgatccctc aattgcacgt gaaattaata gttctgatat taatggcggt aatgttaaat 59640
cgcacggttt tcagatgagg ttttaatgaa attcttttta ggtcaaactg ttgaattaaa 59700
gggagttggt atacctggat taatttctaa ggttctacct ccgtttaaat ggagtggtat 59760
tcaaataaaa gaggcttata ttgtttcttg ggtagatgga aatgaagacc ttcgtgtggg 59820
cgatgaatta tctcctatct acggattaaa ggaattagta tgaatataat taataagatt 59880
tttggaattc agtacattaa ggtcacatat aaagtaacag ataaaaatcc gtatactgat 59940
gaacacgaag aaccgcaagt taagtctatt atattagaaa aaggcagtga ctggccagtt 60000
gaatttcgtc taccaaacta tggtcattgg gctgatgttg aaattataag cattgaaaat 60060
gtctgagtta gagattagaa gcaattttag gtggccatca tgcgcattaa gtaatttcgc 60120
ccaatggcct ttcgttatgg atggcattca atttggaggt cttgaaggat tcctccaagg 60180
gtgcaaggtg aaaaatgttg aacaacaacg tcgtatattt gggttatccg ggcttgcagc 60240
ccaacaagct ggaaggtctt atgcaagagc tcaggaccgt gggaccctct tctggcttgg 60300
agttccattt tcaagatact ccccggcgtg gaaagaatta tacacaaatg catattttga 60360
agcagcgatc caaaacaagg gcttccgtga tgcattacaa gcctcgaaag gaaaagtttt 60420
gaagcacagc atggctagtg gtctaacaaa agatgatata atactaaccg aagctgaatt 60480
tattgatgtg ttaaacctat taagagactc tctatgaagc ctactatttt aactgatatt 60540
gatggagtat gtttaagctg gcaatcaggc cttccttatt ttgctcagaa atataatctt 60600
ccgttagaac atattttaaa aatgatccag gatgagaaat ttatttctcc tggtaaacta 60660
tttaattgcg atgaagaact tggcgttaag ctaattgaaa aatacaatcg ttcggatttt 60720
attcgatact tgtctccata taaagatgcc ctgtgtgtaa ttaacaaatt aaaagaagat 60780
tataattttg tagctgttac agcattgggt gattctattg acgctctgct gaatcgtcaa 60840
tttaatttga atgctctttt tcctggtgcc ttctcagaag tactgatgtg tggtcatgat 60900
tcttcaaaag aagagttgtt caaaaaggca aaagaaaaat ataacgtaat ttgttatatt 60960
gacgatctcg ctcaccattg cgatcatgcg agtgaaatat taaatgttcc tgtttattgg 61020
atggctcgag gggaacgtga cagtattcca aaaactgcac agcgagttta tacatggaat 61080
gatgtagaaa ataagctttt ttcaccaaag gaaaataaag aaagttttga tagtgaaaaa 61140
gctataaaag atgtaattga gaagatgatc aaaaacgatt cttttcgttg gaacactact 61200
tggagaactc ctggatttaa tccttataat ccatatcatc catattatac acactcacat 61260
cagatgcatc cattccatac gtggagttat attaagcctg gcgacgcagg gtattttaat 61320
agacttacta gtggtagtgg tgataatatt ttccaaggag cattctaatg tttgttgttc 61380
acactattta tgaaaatgaa ggtaatacta cacgtgatta cggtcacgta aatcaatttt 61440
ttagatgcaa tccagaattc cgagctcaaa aagacgaacg aatttttaaa aaatgtgtag 61500
agcaaggttt catttacgtc aagcactgga tgcaaggaaa taaagttaga accacgtacc 61560
acaggtcttt gactgagctt aatgatgaat tgatttataa tagagctgta aaccaaactc 61620
taaaggatga acaatgattc ttaaaattct gaacgaaata gcatctattg gttcaactaa 61680
gcagaagcaa gcaattcttg aaaagaataa agataatgaa ttgcttaaac gagtatatcg 61740
tctgacttat tctcgtgggt tacagtatta tatcaagaaa tggcctaaac ctggtattgc 61800
tacccagagt tttggaatgc tgactattac cgatatgctt gacttcattg aattcacgtt 61860
agctactcga aaattgactg gaaatgcggc aattgaggaa ttaactggat atattactga 61920
cggtaaaaaa gatgatgttg aagttttgcg tcgggtgatg atgcgagacc ttgaatgcgg 61980
tgcttcagta tctattgcaa acaaagtttg gccaggttta attcctgaac aacctcaaat 62040
gcttgcaagt tcttatgatg aaaaaggcat taataagaat atcaaatttc cagcctttgc 62100
ccagttaaaa gctgatggag ctcggtgttt tgctgaagtt agaggtgatg aattagatga 62160
tgttcgtctt ttatcacgag ctggtaatga atatctagga ttagatcttc ttaaggaaga 62220
gttaatcaaa atgactgcag aagctcgcca gattcatcca gaaggtgtgt taattgatgg 62280
cgaattggta taccatgagc aagttgaaaa ggagccagaa ggcctagatt ttctttttga 62340
tgcttatcct gaaattagta aagctaaaga attcgccgaa gtagctgaat cacgtactgc 62400
atctaatggc atcgccaata aatctttaaa gggaactatt tcagaaaaag aagcccaatg 62460
tatgaagttt caggtctggg attatgttcc gttggtagaa atatacggtc ttccggcgtt 62520
tcgtttaaaa tatgatgtac gtttttctaa actagaacaa atggcatcag gatatgataa 62580
agtaatttta attgaaaacc aagtagtaaa taacctagat gaagctaagg taatttataa 62640
aaaatatatt gaccaaggtc ttgaaggtat tattctcaaa aataccgatg gattgtggga 62700
aaatgctcgt tcaaaaaatc tctataaatt taaagaagta attgatgttg atttaaaaat 62760
tgtaggaatt tatcctcacc gtaaagaccc tactaaagcg ggtggattta ttcttgaatc 62820
agagtgtgga aaaattaaag taaatgcagg ttcaggctta aaagataaag ctggcgtaaa 62880
atcacatgaa cttgaccgta ctcgcattat ggaaaaccaa aattattata ttggaaaaat 62940
tctagagtgc gaatgcaatg gttggttaaa atctgatggc cgcactgatt acgttaaatt 63000
atttcttccg attgcgattc gtttacgtga agataaaact aaagctaata catttgagga 63060
tgtatttggt ggttttcatg aggtaactgg tctatgaaag cttacttaga aacaattgtc 63120
gtggctcaaa aagaaggtgg agatgtttct acttctgtat cacaaatcgt tctcgaattt 63180
gtagatgcat atgcttataa taaatttaca gaaacatttg atgcctacga aaaaggtcca 63240
aagtttgaaa tatatcgtac tctcttacca ctagattact aaaggccttc gggcctttaa 63300
ttttataaat agaataaaca ctagagagga tatgatggaa ctaattacag aattatttga 63360
cgaagatact actcttccga ttacaaactt aaatccaaag aagaaaatac cgcaaatttt 63420
ttcagttcat gttgatgacg caattgaaca accaggcttt cgtttatgta cctatacatc 63480
tggaggtgat actaatcgtg atttaaagat gggcgataaa atgatgcata ttgttccttt 63540
tacattaacc gctaaaggtt caattgctaa attgaaaggt cttggtccaa gcccaattaa 63600
ttatatcaat tcggttttta ctgttgcaat gcaaacaatg cgtcagtata aaattgatgc 63660
ctgcatgctt cgtattctta agtctaaaac cgccggtcaa gctcgacaaa ttcaagttat 63720
tgctgataga cttatccgta gtcgttcagg tggcagatac gtccttctta aggaactctg 63780
ggattatgat aaaaagtatg catatattct tatacatcgc aaaaatgtat cactagaaga 63840
cattccaggg gttccggaaa ttagtaccga gctctttact aaagttgaat cgaaggtcgg 63900
tgatgtttat atcaataaag atactggagc tcaagtaact aaaaatgagg caattgcagc 63960
atctattgca caagaaaatg ataaacgttc tgatcaagct gtaatcgtta aagttaaaat 64020
ttcccgtaga gcaattgcac aaagtcagtc gttggaatct tctagatttg aaacaccgat 64080
gtttcaaaaa tttgaggctt cagcggcaga attaaataaa ccagcggacg ctcctttaat 64140
ttctgattct aatgaattaa cggtaatttc tacttcagga tttgcactag agaatgctct 64200
tagcagtgtt acagctggga tggcattcag agaagcttct ataattcctg aagataaaga 64260
atccattatt aatgcagaaa taaaaaataa agctttagaa aaattacgaa aagaatctat 64320
tacttcaata aaaactttag aaactattgc ttctatcgtc gatgatactt tagaaaaata 64380
taaaggtgct tggtttgaaa gaaatattaa cagacattcg catttaaacc aagatgctgc 64440
aaatgagtta gtacaaaatt cttggaatgc aataaaaaca aagattattc gaagagaatt 64500
acgtggatat gctcttaccg ctggatggtc attacatcct atagtcgaaa ataaagattc 64560
atctaaatac acaccagcgc aaaaacgcgg aattcgtgaa tatgtaggtt caggatatgt 64620
agacatgaat aatgctcttt tgggattata taatccagat gagcgtacaa gtattttaac 64680
agcacctgaa atagaacaag ccattgataa tttagattca gcctttaaaa atggtgaacg 64740
attaccaaaa ggtattactt tgtatcgttc acaacgaatg ttaccttcaa tatacgaagc 64800
aatggtaaaa aatcgagttt tttattttag aaactttgtg tcaacatcat tatatccaaa 64860
tatttttggt acttggatga ctgattcatc tgtgggtgtt ttaccagacg aaaagcgttt 64920
aagtgtttct attgataaaa ctgatgaagg acttgtaaat tctagcgata atttagttgg 64980
aattggatgg gttattactg gggctgataa ggtcaatgtt gttttacccg gtggaagttt 65040
agcgccttca aatgaaatgg aagtcatttt gccacgtgga ttaatggtca aagttaataa 65100
aataactgat gcatcttaca acgatggaac agttagaact aacaacaagc ttattcaagc 65160
tgaagttatg accacagaag aactcaccga atcggtaatt tatgacggtg accgtttaat 65220
ggaaactggt gaattggtta caatgacagg tgatatagaa gatagagttg actttgcatc 65280
atttgtttca tcaaatgtta aacagaaagt agaatcatct cttggaatta ttgcgtcttg 65340
catagatatt gcaaacatgc cttacaagtt cgttcaagga taaatcatgg aacttattac 65400
agaattattt gacggcgctt cggcgccggt tgttaactta aatcctaagc ataaaatacc 65460
acaaattttt gctattcaag ccggcgaaga aagcgtgctt cctggattta gattttgtac 65520
atacacctct ggcggtgata cgaataaaac gttaagccgg gcgataaaat gatgcatatc 65580
gtaatgatag gtgttaatga gaaactatca ttagttaagc ttaaaaactt gggtggaaat 65640
ccaattggtg tcattaatgc tgtttttgat actgctcttc aaacaatgaa acagtataaa 65700
atcgacgcat gcctattacg cgtactaaaa agttcaaaat gtagtttaca agtccctcgt 65760
gttgtgttac agtagtctta ctgacataac atgaggaaca caaaatgaaa tcttctttac 65820
gctttttagg tcaagaactt gtagttgaag gcgttattcc tgctgataat gcttttaatg 65880
aagcagttta tgatgaattt atcaaaattt tcggaacaga taaaaagttt ggaatttttc 65940
cttctgaaaa tttttcaaag ccagaacaga ctgaaagtat ttttcagggt gtagtaacag 66000
gtaaatttga gtcagaagct ccggtaaaaa ttgaagttta tattgaagac agtttagttg 66060
cttcagttgc tgctttcatt tcattccgta aataaaaata tggggaccga aaggtcccca 66120
ttgttatatt actcctaata ttttactttg cgaattgaca atccctgcca tagtattaat 66180
gtttgaaatg cttcccgcag ttcctcctaa tctactaagt cgtgaaagcg aattagataa 66240
tccagtaacg cctccgctat ttccgagaac gctttgaatg ccatttatag cagcagattc 66300
aagccactca agcgcagctt gtctatcaac cgacccagcc tgcatgactc tatatgcaaa 66360
agtaacatca aatgtagtta tttggttatc tccatcatat gataactcag gagcgctcac 66420
tgacactgga atgcatccgg tgaacatcac ggcagtatga ggtaatccat tacgagcatg 66480
aagattaacc tgaatatctg cctcgacatc ttgcggcaaa gcacgcagtc cagttactgg 66540
gtcttgaaca gcgttaaccc agtcttgcat cgcacgatag ttacaagctt ctgaatccat 66600
tctaaatgaa ataaccaaag ggtctaattc tctcccagtt atacgaatat taggagaatt 66660
atagttccag tcagtttcat aggataatct attctctggc atttttacag agtatatcat 66720
caatccagat gagttatatg ccatgttaaa gaagtcaatt aaatatgtac caactgtaaa 66780
tgagcccaat aaactttgaa ctgtacgttg actcatggca ccaataagat atttactaac 66840
tcctgatttt cttatcagtt tttgtgtgcc agcagtaatt agcgtggtaa ttccctgatt 66900
aatatcgcct tgagtcaatc ctaaccaatc tgaatttaaa cccaagttat tataagaaaa 66960
gttgctaatt gaacttatca acgaagagct tttagttgat ggagttgtcg caaaaacgca 67020
gctaaacata ttattacgtt ggaaatctgc gtttattgct tgattattaa attcctctaa 67080
agaatacatt aaaaagtccc cgcatataaa gaagcacggt ttaacgtgat aatttctctc 67140
atagtaatct cgagagtaaa tgtactaggg aggtttggag caatagctaa tccgttaaag 67200
ttaccattag gtgttttatc aaatctgata ctctgtattt ggcatgggcc aaatatttcc 67260
gtttttccat caaacttaga tgttgcacca aagtttttca ccatccaaat tgtcgggttt 67320
gaaactacta gaacgttagt taaactcgat gtcattttct caaatagtgt tttattttta 67380
gctgcgtctt ccggagataa aggttcaatt aatgtagaac gataccaatc atctaaatat 67440
ccctttattt cagcagcata ttgagattta cccgtttcac cataagaaaa atagttaaaa 67500
tattgataga tattaataat agccattaaa tcttctgtgg aacgtggagt caaatcccat 67560
gtaaacactt tagttctatt ctcagcacca ccatacatac ttctggctgt cgtataaatc 67620
tgttcattat tatcagccat tataccttgt gttatacttt ccagtgctcc aaatactgca 67680
gttgaagcaa tattacttag cacaccagta gcagttcctc cgcctctact gataagactt 67740
tcttgaacat cattaaatct atgtgatgat gtatcaacgt cagatttaga tctcggtaaa 67800
agaatgtttg ccacaggagc tttacttatt gttcctgaat tattatctga tattaatcca 67860
tttgacagtt ttgatactgt actactaata gtgtttctag ctgtacttaa aatactcgaa 67920
gatgaagaag agtagttaga tctcatcgat ctaagacttc cagaatccct agatgacata 67980
ttgtatgcag taaataataa tccattctta tatagatctg ttacctggaa gtcccctgta 68040
gtgtcattac cactagcacg cccagttgga aactgggcag tgtatgtttt agttgctact 68100
tctgatttag tactctgtcc ggctgaaatt ttctcaccgg actttttaat taaatcagca 68160
gttatttctt taacaattgc catattattc cttaattaac tccagtcgcg ccaaatacac 68220
caggagcagt cgtgctcgtt acgggtgtca tattatgaac gacagtattt ttcttaataa 68280
cattattagt attattgatc gaaggagatg cttgttgaac aggagcttgc tgtgctttgt 68340
tcttttctat tacctggact tgttttgctt ctggcgattt agcagaagtt tcaggtttgg 68400
cattaggctg atttttcttg agctcttgat aagtagcatc aattttagaa aatctagcag 68460
caagttcttt tttaactgcc ggtgaattat ttaaatccgg gtcatccatc cgttttttaa 68520
ggtcttcata ggcagcttca actgatttaa ctgttgagtc tttactcata tcagctgaat 68580
cggcatattt ttcaaaacga atcatcgcgg cgcgtgcttc attagctttc attaaagcat 68640
tttttctttc ttccggtgaa agttgcttta atttttcttc ttctgctgca cgttcttcat 68700
ctgttgtcaa tgattcttta ttatcaacac cacgaatcca gttagatgca cgagttttcc 68760
agttcgcaat tttgtctagt ccttctgcta tcggaccaag gtctccattc attcgtttat 68820
cttgataatt cgcaactttt tcctggtctt ctttattgag agatgctcca gtagaatttt 68880
ggaaattttc tagtgctctt ccttctactt catcagcagt atccttcatt ccaggaatga 68940
ctcgaagaat tgcagcagat aatttagcca ttccaagctg aataagttct cctaaattat 69000
aaagaacctt tccaagccct tctacaatag ctaccgtcaa accgccccaa tctccctctt 69060
cccagaattt tttaatttca tcgatagaac taaagatgct ctgtaataaa ggaccccatg 69120
ttccggtttc gctagagaat ttagtaaagt ctgtactaaa taaatcccaa gcctgcgaaa 69180
atttatctga ccaatattta aagtgaacca tcagcagatc tattccaaca acaacagcca 69240
atatcattgc agtcatttta gcagcttcaa tagcagcact gacggtatac ttaaataaca 69300
tgctcgatat tttatcagta attgaaatgg acttcttaaa tccaaaatca acagtcttcg 69360
ttaatttatc taaagcttga gataatttta agttaaatgc gtcttttttc tgtttttctt 69420
ctggcgattc ttgtttgggc tcaactggct gaggggtagg gaaaaaatca gcatcaggat 69480
cattattaac tgcttcagga gctggtaata aaggacccac agattcagct gtatcgtcct 69540
caacaacttt aacaggaata gcgctttcaa ctgtagctaa actagttcca gtttgttgaa 69600
ttccagctgt ctggattttt tgctctagta aactcgttaa tttatctaat ttacttccga 69660
gtgattcacc gatttcttta ttaatattgt tgccaatttc gacagtttca gcaattaact 69720
cagaaccagc agtagtatca ctcactgcgt tttctacgtt gtcaattgct ccaattattt 69780
cattcgattt ttcttcgaca gtttgagcaa ttaattcaga agcagcttga gcatcatcca 69840
atttcgtaga tatatcgtta agtccagata aagtgttgga agcggattta gccgcttcct 69900
gtgttggttt attatctgaa ataacttttc tacgcatcgt ttgcatttct tgtggctttt 69960
tcattcaaat aatccaataa tattaccaat tccagttatt ggaccattag ggccaggaat 70020
tgctaaagtt gtaaaaatat catttgccca ttttaaaacg aatgctggca tctcaagaaa 70080
attaatttct ttaacttcat cattgacctt aagcaagcat ttggataaca tatcgctcac 70140
tgttaaaaat tgttcaaatt ttccaggagg tctaaaataa aatatatttc cttggtattg 70200
aaattctaat ctttggcata cataaacatc attaatgtca taagtatagc catctatttc 70260
tttgcgagat ttaatctttc cattaaattc caataaatga atagaaacga aatcaacttc 70320
tgccggtgat aaattcggac aaatagaatc gatcaaaagt tttaaatttt catcaggacc 70380
tttaacatcc tttaaaatgt tataatgttt aagacccatt ttaggaatag aaacttcttt 70440
attgcttatt ggaagaacta ctttcttcag tggtagtatc agatttaaat tcatttttaa 70500
ccttaactgg gtctattgtt tccagtttcg ttgcattagt gaacatatat agatgagtta 70560
ttgaattatt attggataat tcatggataa cttcatcaac gtaaaattct gttttaaatt 70620
ggtttttact atcattaaaa ataattttaa cgccaggagt caagttaaaa ttaccgacag 70680
tagaacattt agcatagcca tcgtattgcg ccatagtttg aagacgaata gcttcttcat 70740
atccattcct ataagtcatt tcagaataag cacctgacct tgacactaca atagagtttt 70800
cgccctttcc tgtagtaatc attggcaatg aagaatctaa aaatgaatgc gcatagatag 70860
tagcgttttt cattgggtca cgtttgtgag gattcgattt agtcaaccaa acgaaatcat 70920
atgctaatgg atattttaat tcttggatga attgacctat taaagatggc tcaccgacaa 70980
tcattggata tggttcttga tttatcatca tatcatagtc catcatgtta actcccatga 71040
tgtcttgcca tacaaataca aatttgtcac ttcctacagc tagagcaact tctctgacat 71100
acgacaaata gttttcaaat gtgctagtcc atggaatatc aggaacataa gcatttatag 71160
catttattgc tggagttaat aatgtgcgat cctgataaat gacaccaagc atttccttta 71220
tagattcacc tacatcagag aaaaacggtc tgccaaattt aagattttct atggaatgaa 71280
tagttcccaa ttcaatagca atgatgttat cgccctttga atctacagat acagaaaaat 71340
gcttacatcc ataaattcgt gttttaacat tattaatatc gtttgcatta gctacagaaa 71400
tctgaattat ttcatttcca tccatttttg tatggatatt tttagaatca taaaactgca 71460
acattccttc atttcggcca taaagagaat cccgcatagt taatgtggta atagtagcag 71520
ctaattcaac aaatctatta ttactccaag cgtcgtagct atcaaataat ttaacgctga 71580
gatttggata tccagggcgt tgcaacatac tcattattgt ttatccttct caatcagttt 71640
taatacgaat ccgcgctcag caggaatcat tttcattatt gaatttaagc tataattact 71700
ttttacgagt gtgtgattaa tttgataaaa agtaaatatt tcatctgggt taactaatag 71760
cttaaacaca tctactatat cggtgtattt tttaatgtac ttattacagc atgacatatg 71820
tagagttaaa ttaataggat tcattgcatc gagaattttt tctagtgttt ctatctcgat 71880
ggcgtcaact agttctattt gacttgattc actaatttcc ttccaatcat accaaatttc 71940
atctacttga acagaatgaa tattttcagt aatcatcttt gctttatttt cataaaactc 72000
agaaggaaac tttaatttaa ttttaacatt agctacatca aaaacaggtt cctttaattc 72060
tttttgatat atttcaaatg gaactgtctt ttctttttta cattttggac atacgaatgt 72120
gactggtact ttagttttac ctattgaccc tacaaatacc tgcaaaaata taaatggttg 72180
ccaagtcttc ggatagtctc caaaataatc atcaattaaa tcagtaatta tttctttttg 72240
ttcttgtggt gaccgatgtt ctatatcgtt tcgaactaac aaaaaatctc gataatcttc 72300
taccgtaaat ggtttaaaac gatgaacacc atctggtaat ttacaacgaa taatgtttgc 72360
catagatgct ccttttattc tatttataaa tatgataaat aaaggagcta aatatgtatg 72420
aatacaaatt tgacgtgaga gttggttcta aaataatcaa ctgtcgcgca tttactctta 72480
aagaatatct agaacttatt actgctaaaa agaacggttc agtagaagag atcgttaaaa 72540
agctaatcaa agactgtaca aatgcaaaag atttaaaccg ccaagaatca gaactcttgt 72600
tgattcattt atgggcacat tctcttggag aagttaatca tgaaaactcc tggaagtgca 72660
cctgtggaac tgaaatacca acccatataa atctattaca tacacagata gatgcaccag 72720
aagacctctg gtatacactg ggtgacatta aaattaagtt ccattaccct aaaatttttg 72780
atgataaaaa tatagcccac atgatagtat catgcataga aacgattcat gctaacgggg 72840
aaagcattcc agttgaagac ttaaatgaaa aagagttgga agatttatat tctatcatca 72900
cagagtcaga tattgtagct ataaaagata tgcttttaaa gcctactgtt tatttggctg 72960
ttccaattaa gtgtccagag tgtggaaaaa ctcacgctca tgtaataaga ggactcaaag 73020
aattctttga gctattgtaa tggcaaatat taataagctt tattctgaca ttgacccaga 73080
aatgaaaatg gattgggaca aagacgtttc cagatccctt ggattaaggt caattaaaaa 73140
tagcctttta ggaattatta caactagaaa agggtcaagg ccatttgacc cagaatttgg 73200
atgcgattta tctgatcagc tttttgagaa tatgactcct cttactgctg atactgttga 73260
gcgtaacatt gaaagcgcag taagaaacta cgagccacgt attgataaat tagcagttaa 73320
tgtaatacca gtttatgatg attatactct gatagtagaa atacgctttt cggtcatcga 73380
taaccctgat gatattgagc agataaaact gcaactggct tccagtaata gagtataatg 73440
cttcacgtat aaacgtggta taatgaatct aagtccatcc aataacaatt gaatagagaa 73500
caatatgaaa ttagaagatc ttcaagaaga attgaagaaa gatgtgttta tagattcgac 73560
taaattacag tatgaagcag ctaataatgt gatgttatat agtaaatggc tcaataagca 73620
ttcaagtatt aaaaaggaaa tgcttagaat tgaagcgcag aaaaaagttg ctcttaaagc 73680
taaattagac tactactcgg gacgaggaga tggtgatgaa tttagtatgg atcgttatga 73740
aaaatcagaa atgaagacag ttctatcagc tgataaggat gttttaaaag ttgatacttc 73800
attacaatat tggggaattt tattggattt ctgtagcgga gctcttgatg ctattaaatc 73860
acgtggattt gctattaagc atattcaaga catgcgagca tttgaggctg gaaaataatg 73920
aaatatagca ttgatgatgc ttttaattat gaagaagaat tcgaaacgga aattcaattt 73980
ttaatgaaaa agtataatct caagcgtcag gatattcgta tcctggccga ccacccatgc 74040
ggtgaagatg tactttatgt taaaggaaaa tttgccggat atcttgatga atatttttat 74100
tccaaagata tgggcattga tatgcatatg agagttatat aaatagatat ataatttaga 74160
ggagacaatc atgtcagata agatttgtgt tgtctgtaaa actccaatcg attctgcatt 74220
ggttgttgaa acagacaaag gtcctgtaca tcctgggcct tgctataatt acattaaaga 74280
actaccagtt tcagaaagtt ctgaagaaca attaaatgaa acacaacttt tgctatagtg 74340
tgacctttag tctatagttt tggcccttcc tttttggttg ggcctttttt aatttaaaaa 74400
ctttcttcta cttcatcgtc tgaatcttct aattcagctc tttttcctgc caaagcatct 74460
ctcacagaga tgtcatcagt atcttttaat tcagtttctt taactctttt cttataataa 74520
gcttcaagtt cttctagacc ttctatcgtt tgacaagagg caattttacc cataaattca 74580
tcaatagaag cttcataaag aaattgttta aattctagta acatcttttt ctccaaaggg 74640
ccgaagccct tataaattaa ctgtttttct aagtattctt agtttgtaca ttgataatcc 74700
agtagcttta gaagcatctt tcatgcattt atacttaaca ccatttactt ctataggttt 74760
agcagctggg ttattagctc ctgaattatc tggcatgtta tctttaattt tctgaataga 74820
tttagcggaa tgtttccttc catacatgcc attattttta cctgattgat tgatagaatg 74880
caatctttta gcttcttcag tccattttgt tgggttcatt cttttagttt tactaatttt 74940
acttccccac gtaattggac gatttttcat gagttttgac atatattgtt tatgttcttc 75000
cgtgtggtgt tttccgtaaa atggattacc ttcacctgat tgaagttctg ccattttacg 75060
acgttcccag gcgtaagatt tattaacgtg tctttcatga gtctttgaat tcatccccat 75120
acatataacg gctttaatta taccgtaatg gtttggatga attttagcta aaagtttatg 75180
agctataaaa tgctcttcag ctgttagttc taccaaatta cacttatcat ctgtaccgcc 75240
catacatcta ggaattatat gatgagtttc agtgtatcca ttaaggcgag cccgattctg 75300
ggctctatta attaaattat cgtatattaa tttataattc aaagtttaac ctctttcatc 75360
acataattaa acttctcatc agcataacgc tgaatacgat caagtccatg ttttaaaaga 75420
tagtttaaat gcgagtattt tttagaagat gtttttgatt tagaaactac gcccgcgtca 75480
tctatgaggt cccagaccgt tgcgattgtt ttagaaccat gcttacgtaa tacgcgaccg 75540
attgtttgca atacaataat tttagattta acaccgtgcg ctaaaacaac gtgatgcaga 75600
tttttaactg aaataccagt agaaaataca ccataactag ctactataat tattccttta 75660
ccgttttcag ctaatgtttt cattacgtta cgtgtttcgg tatcaacttc ccctgatacg 75720
taataaactt tatcgtattc atttttaatt aaatcgaaaa tagctttacc atgtgataca 75780
tgcttaaaca tgacaaaagc gttttcatct ttttgtgcaa gtttaatagc taatttagca 75840
atccatttat ttcttttact gagcccagta ataattttta tttcttcttg gtaagttttt 75900
ccctttaatt tagtagtgaa ctcatcagga tagcgaagaa aaatactatt aatttttaac 75960
tcagttactt gtccatcttc cattaattta gaagtcgtta ctggcttaaa tatttcacca 76020
aacattccaa catactgcat gatattagct ttgccatcac gtaatgaacc tgatagacca 76080
aatttgaaca tgcagttatt taaacctgat atgatagatg aaatactttt tcctgtggca 76140
agatggcatt catcattcat catcattcca aactgtgaga accattcttt tggttgtttt 76200
actacagttt gccatgtacc aacaattacc ggtgcatcat ttttatattt atcatctttt 76260
gatgctccgc cgccaatttt ctttatcatt gcatgactga ataaacgata gtcaacaaag 76320
tcatcagcca tctgagttgt cagagcagtt gttggaacaa tgataagaat tttaccttca 76380
taattttcca aataataacg tgcaagcaaa gcttgaatta aggatttacc tgcggatgtt 76440
ggaagattaa gaattctacg acgattaact aatccttcga acactgcatc tttttgatac 76500
cagtgtggtt caattctttt atttcctgaa tagatttcta acttagaaag ccattcatca 76560
aaatcttttc ttgataattc ttctttttcg ttaatttgcg ggtcaatcca agctttatag 76620
ccaaagttat cgcagaactt tttaatttgc ccgactaagc cgaatggaag aagacgatta 76680
taatctaaaa gacggattcg tccatcccag ttgccatatc tgaagcgagg attaaaccta 76740
tatccatcgg cctcaaacga aaagaaatct cttaattcgt ggaacgtgct ctcttcacaa 76800
tcgatgcgta catgactgaa gtcgtgaaaa tgtactttaa tatccataat tatgccttac 76860
taaatttgcc tttagaatct cttttcatga gacgaccttt aataaatccg tcgggaataa 76920
taccgtctgg ttgtattaat ttatttattg cgccattatt aacccaaaaa gttcctgttg 76980
tagtcggttt gactttgcat ccttttctgg actttctatt aggatgaacc atccctttta 77040
caaatccttc tggaacaagt tctccaggct taataaaaat atttttagtt ccattagtgt 77100
aacaagttgt acctaatact gtaccaggtg agttttcaaa tctcttagcg gaagattctt 77160
tcatctttgc tataacctct gtagtcataa caattccacc aattccacca ggtttcatat 77220
tataataatt tttgcttttt attagttcag gagttataat ttcttcttca tacatgtacg 77280
cttcttcgga agttttaaac tcttttagta tttttctaga gaaattgttt tcaccatatt 77340
tctttatagc ctgctgaatt gccttaccgg aaccaaggta gccatcattc aggtcgtcag 77400
tagagtgctt tcctatatac tttttaccat ttattagatt tgttgtttca tatacaaagt 77460
ggtacatact attttccgag taataaatat atctatattt atactgagga aatattatga 77520
tagataaaga ttatattgca gagctgaagg ctcttgatga taataaagaa gctaaagcta 77580
aattagctga atatgctgaa cagtttggta taaaggtcaa aaagaataaa tcttttgata 77640
atatcgttgt tgatattgaa gaagccctcc agaagctcgc tagtgaacct atgccagaga 77700
ctgatgggtt atctattaaa gacttaatca atgctgctga tgctgcagag ggattaaaat 77760
atgacgatga agaagtcaat ccagaggcag cacttctgat tgattctccg gttaaatctg 77820
atattaaaat tgaagtagtc gaaacggata aaattcctga aaataccgat gttttgattg 77880
aagatactcc ttttgttgaa gaaaaattcg aacaggctgt agttgagatt attgaatctg 77940
aaaagccgtc tgtatttact cttccggaaa actttagtcc gaatcttcag ctgattggaa 78000
aaaatccagg attctgcact gttccttggt ggatttacca gtggattgct gaaactccgg 78060
attggaaatc tcacccaact agttttgaac acgcgtcggc acatcaaact ttatttagct 78120
taatttacta cattaaccgt gacggatcag ttctaattcg tgaaacacgc aactcttctt 78180
tcgtaacatt aaaataagga taacttatgg cttttacagt tgatataact cctaaaacac 78240
ctactggagt tatagatcag actcagcagt ttactgctac acccagtggt gaaactggag 78300
gtggaactat tacctatgct tggactgtag acgatgttcc acaggatgga gctgaagcaa 78360
cttttagtta tgtactaaaa ggacctgccg gtcaaaagac tattaaagta gttgcaacaa 78420
acacagttcc agatactgat gctgaaacag cagaagctac tacaactatc gcagttcaaa 78480
ataagacaca gacaactacc ttagctgtaa ctcctgatag tcctgctgct ggagtgattg 78540
gaactcctgt tgaatttact gctgctttag cttctcaacc atcaggcgca tctgctacat 78600
atcagtggca tgtagatgat tctcctgtta gtgaagcaac ttccgctaca tttagctata 78660
ctccaactac aagtggagta aaaagaatta aatgcgtagc tcaagtaaca gcgacagatt 78720
atgatgcaaa ggaagttact tctaatgaag tatcattaac agttaataag aaaacaatga 78780
atccacaggt tacattgact cctccttcta ttaatgttca gcaagatgct tcggctacat 78840
ttactgctaa cgttacggat gctccggaag aagcacaaat tacttattca tggaagaaag 78900
attcttctcc tgtggaaggg tcaactaacg tatacaccgt tgacacctca tctattggaa 78960
gtcaaactat tgaagttact gctgtcgtta cagcaactga ctatgacagt aaaacagtta 79020
aagcaacagg ccaagttcag gtgactgata aagttgctcc ggaaccagaa ggtgaattgc 79080
cttatgttca tcctcttcca catcgtactt cagcttatat ctggtgcggt tggtgggtta 79140
tggatgaaat ccaaaaaatg actgaagaag gtaaagattg gaaaactgaa gatccagata 79200
gtaaatacta cctgcatcgt tacactcttc agaagatgat gaaagactat ccagaagttg 79260
atgttcaaga atcgcgcaat ggatacatca ttcataaaac tgctttagaa actggtatca 79320
tctataccta tccataatct taggggcttc ggcccctttc ttcattttga aagcacacaa 79380
accacaatca gaaaacgatg tatataatgg caccaactcg ataacatgag attgattatg 79440
agaactgagg ttgtggtgtt tactcttcat gagtctggaa agtcattcat tgaaattgct 79500
cgtgaattga acttacaggc aaaggaagtg gctgtattat gggctcgagc tatgactgct 79560
aagaataaat ttgagactcg agaaaaagtt gtctatagaa aaagacatat taataaaaag 79620
gtgaaaaatg gaacagtatg atctttatga aaatgaatct tttgctaatc aattacgcga 79680
aaaagcgctt aaaagtaaac agtttaaact agagtgtttt attaaagatt tttcggaact 79740
tgctaataaa gcagctgaac aaggtaaaac atattttagt tattattgta ctgctcgcga 79800
taaattgatt actgaagaaa ttggtgattg gctgagaaaa gaaggattta gctttaaagt 79860
caatagtgat cagcgtgatg gtgattggtt agaaattaca ttttgaggat taattatgtt 79920
taaaaagtat agcagtcttg aaaatcatta caattctaaa ttcattgaaa aactttatag 79980
tttaggattg actggcggcg aatgggtagc tcgtgaaaag attcatggta caaatttctc 80040
gttgattatt gagcgcgata aagcaacttg tgctaaacgt actggaccga ttcttcctgc 80100
tgaagatttc tttgggtatg aaattatttt aaagaattat gctgattcca ttaaagcagt 80160
acaagatatt atggaaactt cagcagttgt atcttatcaa gtcttcggtg aatttgctgg 80220
acctggcatt cagaagaatg tcgattatgg cgataaagat ttttatgtat ttgacattat 80280
tgttactacc gaaagtggtg atgtgactta tgtcgatgat tatatgatgg aatcattctg 80340
taatacattt aaatttaaaa tggctccact tttgggtcgt ggtaaatttg aagagcttat 80400
taaattgcca aatgatttag attctgtcgt ccaagattat aattttacag tagaccatgc 80460
tggattagtt gatgcaaata aatgcgtttg gaatgccgaa gcaaaaggcg aagtatttac 80520
cgctgaaggt tatgtattga aaccttgtta tccttcttgg atgcctaatg gcaatcgcgt 80580
agcgattaaa tgcaagaatt ctaaatttag tgaaaagaaa aagtctgata agcctattaa 80640
agctaaagtt gaactgtcag aagctgataa caaattggtg ggaattttag cttgttacgt 80700
tacactgaac cgagtaaata acgttatttc taaaattggc gaaattggtc caaaagattt 80760
tggaaaggtg atgggactaa ctgttcaaga tattttggaa gaaacttctc gtgaaggtat 80820
tactctaact caagcagata atccttcttt ggttaaaaag gaattagtta aaatggtaca 80880
agatgtactt cgtccggctt ggattgaatt ggtaagttaa ataaaaaggg accgaaaggt 80940
ccctttgttt tattcatcaa caataatttt tggtagctta acacctaata aaacagacaa 81000
atctgaacga cccgccattt tatccatgtc tccaccatca attattcttg cttctttttc 81060
atcttttgct acagtgtaag gatttgcaga taaagcatat ctaactaata aaccgataga 81120
tggctgcaaa ctttctggat caactacaac tttaaatgca cctacatgtt cagggtcatc 81180
taagtccaga ccttctgtat acggggcata gaaaattgat ccaacaattt ctttttcgcc 81240
aatattttct accacgccaa cgattacata atctaatggg ctgttagtat cgcaataaag 81300
cggtaaacca ttagctaaga acccgtaggc attttgtgaa agatatttgt catcttctgg 81360
tttatgtttt aaccaacctg atgcagcaag aatcgcagcg gcacgagctg aagcaacaca 81420
gaacgttgca gtataagttg attctttttg gatatgcgaa accatttcac ataccattcg 81480
gtataatgaa cgaccagctt caggtgcaga tgcataactc aaatcaatga atccggtatc 81540
agtaattcct gtaactttat agcgttttga tactgtaatc aaagactgta gaatatcttt 81600
attgatttca tccgccattt cagttgcaag caaatcttcc aagaaattag gagcatcgaa 81660
tccatttgct tctaaatctt gcgctaattc aactgtgatt ccagttttaa gtttacgaga 81720
tttaactgcg gtttgccatt tattaatctg gaatctagca tccgcaattt cgctatcaga 81780
gctttcaaat ttgcttgtta ctgcagcatc agaaaataga cgaaccttta aaagaacaat 81840
tgcaatctga agagctaatt ctaaatcgct ttcttcaatg gtagcaaatg gtgtatcttc 81900
taatacttta taaacgatat tattatattt gaataaatcg cctttattga gagttaattt 81960
agactcttct gttaattctg tgatttgttc tcggtctaca tacccagctt caccagcgta 82020
agtagcacca gttttaaatg taaattcgtt atccgggtta aggtatttga taccataaaa 82080
agcagcaaca ggttgattag ttctttgcgt tgctacaatg tcagaatata ttaatttagt 82140
ggtagcgcga gtcaaagcaa cgagatttgg gcgaccgatt gagttgctat tcgttgtggt 82200
tgattcgcgc agaagttcgt tgattttagc cattgcgctt tccttttggt ttatatgatt 82260
tatttatacc ataaaaacaa ctaaagggac ccgaaggtcc cttaaatcgt caaagattag 82320
atacctttaa catatacacg gcggaagtaa gcgtttttac caaggctatt cagaatagaa 82380
ggcataccgc tctggatgcg agaagccgga gcttgagtag cggattctgc aaatgggttg 82440
ataccgatac cgtaacgagt tttgaatccc attaccggtt ggaagttctt cggatcggaa 82500
ccacgcagcg gagtcagagc tacatatgga gcatagtaaa taccagcatc catttcgttc 82560
ggacctttat aacctacagt gaaataatcc tgtttagcat actggtcgat atatacacgg 82620
tatttaccac ccagaacacc tgcaaatact gacttagtag tatcagtatt aaaaccggtt 82680
gccaaacctt gagcagcata agaaatgcca gtatcaacag aagccagtac gttaactacg 82740
ttacgagaag cgataatgaa gttaccttcg ccgcgaccgg tttgacgagc aatttcaact 82800
gcttctttgt caatctggaa caacagagct ttaaaggatt cacccgccca gcgagcacca 82860
cgaatatcaa tcggatcctg gaagtcaaat acaccagctt tagaacccgg agtcagggtc 82920
ataccagatt taccaacctg agcggagtag ttaatccaat caacaacttc acggttgatt 82980
tccagcatga tttcggtagc cagaatacca gacagttcag catcagcatc cataccgtga 83040
acagcgcgga ggtcttgtgc taattcgata gagtaagcag ctttcagctg gcgagattta 83100
gcttcgataa cttgtttatc gatacggaag cccatttcat tccatgggtt atcagtagaa 83160
ccattgaaac cttcctgaag ttcagcgata gaagtagcca taccttcagc gatttctacc 83220
agtacaccag cttccatttg tttcttaatt tcagcatcta atttagctgc atcatcagca 83280
cttgaactaa ttgttactac agaggaagct tgcagatata cagtaccagt ttcctggaag 83340
aaataagtat agatgtcacc tttgacagta gtagcgccag cagttaaagc agtgaatttc 83400
ttagcagcac cctgaccaga gaacattgca tctggaccat acattgggtg gaatgcttct 83460
ttagcgccgg aagcgattgg atctttacca tatactgcgc gcagcgcgaa tacctggcca 83520
gtcgggctgt tcattggctg aacaccacaa atatcgaaag caatcaggtt aggaatagca 83580
cgacgtacca tacccataac agctgggcca atctgagtta ctgcgccaga agtctgacct 83640
gcggcgatgt tggtagcatt gtaaccgtgg tcaccaccga tttcagcttc tgttaagaaa 83700
gaaccgaatg cctgagcaat tttttcgtct ttatattccg gagctgtctg gaaatctttt 83760
tcctggtttt caaagatttt agcgataatc gcttgtttgc tattagcaat ttccggtaaa 83820
ccttcacctt ccagtaatgg cttccatttg ttcaaaagtt cagctttagt tttgatagtc 83880
atttgtgtta acctttaaaa ttagaaacga gatgcgactt tcgcatatac acttacaata 83940
tcttctgcac cttgtgcaga tttatcttct acagcttcag tgacgaaatt cagtccggct 84000
gcttcagtat caggagtatt tatactctca gtaatagtgc tttcatcttt attagatttc 84060
ttcaccattt ctacgattgc actcaattta cttgagaatg catctgaata atccatacct 84120
tcgaccagag cagagacttt ttctttttga gactcagtca gatctttagt actttcgctc 84180
aatgccactt cacgctgcac ataattgata tatgcgtcac gcttattgag ttcttcgaac 84240
agacgagctg attcttcttt atgttcttgc agctcttctt ccatttcagc tacaacatca 84300
actgattctt ctggaacaac aacgttgtgt tcaacaaaga gctcttttaa tccaccaagc 84360
atggattcaa acagttcggc tttgatgcct ttatcaactg ctaatttatt ttcagcgagc 84420
cattctttcg caagatggtc gatgaattta gaagcttgct cagcaatttt cttctcagct 84480
ttttcttcgg cttcttcttt atttttttct acttcttctt ctgctttttc agcaatttta 84540
gcgatatgag attcagctaa tttaacggcg tgctgcttga cggtagcttc gaatacagtg 84600
ccgaaagttt cttttgcttc cggagaaata ttaactgatt cgaaaatact atcaagagca 84660
acggaagcat caattttttg cgattcagca atcagttgtt ctttaagcat tttgtagtcc 84720
tgttgtttag ataataatat ttataacgct tttttcatgg cctctgcgag agccatatag 84780
gcgtcatcgg cacttgtatc ggcttccgcc gtctgtgatt cggtaatttc cttaggagtt 84840
acccatgcat ccggagcact tggaccccat actgcatcaa cacctacagt taatttgaat 84900
ccttcgttta cgatacgata acctttattt gtgtcagtca atgaacctaa tccacgagaa 84960
gaaactcctg gaatccatcc ggcacgaata ttagctgcta atttatctcc aggaccgtgg 85020
tcaccttcaa taacacgagc tcgtccgtat acgtcatttc ctttccacca catatcttct 85080
ataatgatag cggcttgcat cgggtcaaca ttagcgcgtg gaggatgatt taattctccg 85140
agagcttgtt tagttaaaac ttgctcattg atatagtctt ttaccgcttt ttctaatatg 85200
cgttttggat aaagacgttt atttctattg acgacttccg cttgcatgaa tattccttcg 85260
atgtataaac caggttttaa acctaggtct tttccatcat gagattcaag cattggcaca 85320
ccatcaataa tttcgccagg ttgaccccaa gtttcaatta gtaattgggg ttcattcatt 85380
agcttaatcc taatgcttta cggcgtttaa gagctttttt acgcttacgc tgagcacgag 85440
attgacctgc tggattggca atcttcgttt tggtagcttt gcgagcaatt tgtctacgct 85500
ttgctttaga cagcccggtg gtttgaaatg cattacgttc acgcgttttg cggtctttgg 85560
tacgtgtaat ttcaccacga gcagaaacat gtttaacgat gaattcattt agcggcatat 85620
cttcattaat agaagctaat gcaatcgcta aatcagtttc atcatcaagc atattctcga 85680
caattgtatt tatatcgtct ttatttaaag cagaagacaa ttcgtcaaag cgaccctgtg 85740
cttcaggaat aagtgcttcg acattctcga gaactaattc atgagtttca gggatcagaa 85800
gcattattca tcatcctcgt cttcgtcatc ttcgtcagag tctttgtctt ttttgtcgtc 85860
tttatcatcg ctatcttcat catcctcgtc ttcgtcatca tcctcatcat caggttcttc 85920
accttcgatt aagaaattgc gagcgatagc gattttttct tctttaatta aatcaatcgt 85980
tcttgcagcc atggcttcag caaagaattt acgagcggct acgaggtcgt ttgatttaat 86040
agcttcaatt aaaccttcca ttaaaaatcc tcttgttctt ggtcggggtc ttggaaacga 86100
gcctctttag actcttcttc aatttgcttg gcttcttgtt ctatttcttc atcagtcatc 86160
tgcaaaatat ctttcatagc agttctgtga gaaatatatt taccaataaa tggttctgcc 86220
atggttagca tattaattct tcgttccaaa atttctgctt ctttgagttc agtaaagtag 86280
ctatcccgat gaaattctat cttaatatta tttatttcat cattccactc atcttctgtg 86340
attatacctt taagcaacag atttgtttta agcggatcca ggaaaacttc ttcaaactta 86400
tgctgtaact cacgaataaa tttagcaaac gttaattcat cacgtgtaat gctagttcca 86460
gaatcaaaca tcacaccgcc ttgttggtct tgcgggatgc gtgaaagagg aacacgtaat 86520
gccatataaa gagcttgtct aaaccaacga acatcttcca tattaccagt attatcggca 86580
ccaggaagag tatcaacttc tgtcacagct ttaccatcgc ggcgctgtaa ccaatagtct 86640
tcggtcatag acatattatg ctgttgattt tttattttac ctgttgatgc atcatatact 86700
acacggtttt tcatcgtgtt catgacatgt tgcatgtgct cggcagcttt acgagcaggc 86760
atattacctg tgtctacata ccaaacacga cggtcaggag cacgagtaat acgataaatg 86820
actacagcat cttctaataa ttttaattgg ttagcaggtt taacagcacg atgcaaatac 86880
ccgatgatat ttttaccaca gcaatcgact aatccagaat gggcataaac gatggcagct 86940
ttaggaattt ttatttttgt gccagcttca tacattctac catcacatgc atatgattcg 87000
tgtgcagtat catatataaa atactctttg taacctttaa ctatttttgt gccagcttca 87060
gtttctgtta taatttcacg aacatactga acttgacgtg ggtctaatct acgtaattcc 87120
tttatgcctt cttttggacg ttttggatca ataattttat gaaagaaaat tcttgaatcg 87180
acataccaac gtctaaaatg atcagaacct tttcgttgaa atgatagatg atttaataca 87240
tcgctaaatt catctaacat catattttta atttttgggc taaatttaga tttatccaaa 87300
tttaacgcta cgacttcagt atcatcttca tagacgatag cgtctgaaac gatttctgaa 87360
actgcattat ctacttcata gttattcatg agattacgat atgtatcaat aagctcacga 87420
gtagttttca ttcctggttc atatgaacca aaaattgttt ggaatgcagc attataagga 87480
gaagcagctt cattcgagct tacttcaaat tctcttgctc catcatcaag ctttggggct 87540
gtaatggaaa caagatcttc tttttcttgg tctttaaaat ttcgttcgtc cattttagcc 87600
catggagcaa acaaacttaa tacattaaat ttcattgtat tctccaaatg ggaattatag 87660
ttatatttat aatggacttc tctgctttaa gcaggatggg gatttctccc cattcatttt 87720
attcccaata atcgagagca agagttactt caaaggtttg gatttcattg tttgaatccc 87780
aatctaattg aagttcaccc acgttagtag gccacaggcc tttaatttcg acttcttttg 87840
ttacagtttt agcatcacga gcatattggc gaacaacagc actcttttta tactctgctg 87900
gttttccacc agtaatttcg ttcccttgcc cagcagcaat gctttgccaa tcaacaaact 87960
tctggcgagc atcatgtgcc tcatcgttca ttactgtaac agtccagtca tcgaatgtac 88020
gatcgcctgc tacgttaatt ttacggttca taaaaccgac tggaattttt tctacaatac 88080
cagctggtaa agcagtggct ttacattgaa acgtaaaatt ttgtccaaga taagaaattt 88140
ctacttggaa taagttaggt cgagcaaaat caccagattc aaacgctcgt gttacatcat 88200
ctacaaacat attagcctct gtagtattta tatccctatg tttaacctag ggcatataga 88260
attaaagaat taaggatata gtgtatttat atggcctgcc gaaacaggcc tttagaatgc 88320
accgtattaa cctgcaagac cagttaactc atcgaaatct gcaccagtag cagttgctac 88380
gaagtttaag gtaatgtagt taatgcttct agccggttgg atgtagaatg ttgcaacaaa 88440
ctcatttcta tcaattactg acggagtgtt atttgttgta tcgcaaacta cacgatattc 88500
ataaattcca ccgagagctt taattccctg caagtactgg gaagtttctg tgcggaacga 88560
tgaacgagta aacgcgttgt ttaattcgaa caaacgatat tttgaactac gtccgatatt 88620
cgttttcaac atattaaaca gacgacgaac gttaatacga tcaaatggag aaggaacaga 88680
agtagctgtt ttatcaccat acaatacgta accatcacca cctgtaccag ttactgggtt 88740
gatagcttct tggtataaac gatcgcgctg cgcctggcga gtttcaatag caagtttaat 88800
aacgttaaga atctggccgc gattataacc agctggggac atccaagtct gagaaacgtt 88860
atctgttctc gcgcataaac cagcaatatc agctgctaat ggaacccaac gattcacatc 88920
attatatttg tcatactgat acttgtagtt accatcaatt gctgcataag ttgaactgat 88980
attaaagtta ttatcagtgt atgaacctgc tgcggttctc cagttgacta agttatcaac 89040
agcgcgagtt acaggaattc caactacagt ttcgcgcggc ggtgagcaca gtactaagca 89100
atcttggcga gcatccccaa ttgaaacgac gtgtttttgg acagtagatg ctgtttctaa 89160
agattcaccg gcacaagaac ccgcaataaa caactgaaca tcaacagatt cacggtcagc 89220
aaagaaatcc caagcttcca tcaaatctcc tgctgttact tcagcatttg atgataatcc 89280
accagacaga gttaaaattc cagagaagcc ttctggccag ttttgtgcag ttgcaaaaat 89340
atattctgaa ccaccttttg cgaaaaagtc atcgatatag atgttactat cgtaaatatc 89400
tttttcaccg cgcttagttg aaagaacaac gctttgaaca atagcatcat tacgacgaac 89460
tataatagcg tattgcgaat cagtttgtgg tccatatcca aacaccgctt tggcagtaga 89520
tgcgcgtgtt ccgccacctg gataaattgg gagtaatgca gaagctcctt ttgcgtagtc 89580
agctttagat acaatttcga tttcaatttt atcgcctaac tcgcctggat aaagagctac 89640
tactcctgga attccatatt tttcgagatt tgcttgaaat tcaaccgctg tcacagcagc 89700
ttcagcattt tcaatttcag ctaataaaat accggaatca gtaataattt ttccaagagt 89760
tattactgca gctaaaccag aggaagacga agaaatttcc gcggtccagt tagaacctaa 89820
tgctggatat tcaccgactt ctttcgcttt agcgataatt tttgcggtag gaatattaat 89880
tttcttaatt tttccatcag catctacttc ggtaatttta ccatctgttt caacattttc 89940
tgaaacatac ttaaccgtga ttttatctcc aaccgcgtag ttactacctg gggctgaaat 90000
agtgtattca atattaccgg caatcggaga tgagttttta gcggtatctc tatcgacagc 90060
acgcacaact cgcaaatcat ttccgtattg taagaaattc attgcagaca taaaatagtc 90120
agcagtttca gctgtaggtt gaccaaaagt attaactaaa tctacttcat ttgtaacctg 90180
tttaatttga aaagcaggac cccactggaa tttaccggcc aaagctgctg taccagtaga 90240
gttattaacc acggtgcttt gaaccgtagt ttctttgagc tcaatgcccg gagataataa 90300
agtcattttt aatcctcttt aatatgcttt aatatattta taccattgac ataccatgag 90360
atactggaac atactcagca gaatgaaccg aatcaacaaa tataactgga gcgtattcat 90420
cacccatatc ttggagttct tttgaaaaca cttcagacgc taatcgcatg tcatctttgt 90480
cagcataatc aataaatttt gattgcgttg ataaccatcc aaaaatcact aaagacatta 90540
ctaaatcgtc gtgataacct tcttcagccg cccaagacac gcctttttca ctaaacgttc 90600
taaactcttg aatagttgca cggtgatgaa taataagctt atctttttca ataaggtctt 90660
ttaatgtaga gcatcctact gctttcgttc gtttagtttg cttcattcct aaatcagtat 90720
atgaatcgca aataacgcct tcgtattcta aatccatata aagtgatttc gcaactgaca 90780
caccagtact atttaattca atataaactg ggcattcatt atattctact aaataacgca 90840
taacgatgtc aggcagaatt aaatgagaaa tggtgtttga atgtaaaaca ccaacctgtt 90900
cccacacatc atcggtaaca tcaataatat gtaaagcgtg ataatcttgc ccacgacctt 90960
ctgaacagtc taaagttgca atatattttc tatctggttc aggactttta aatcgatgaa 91020
aaccgtgatc gtctggagtt acttcaatga aatccataac agctaatttc attcctgaaa 91080
ttaatgtacc agaagtccct tcaaacgctg cggtgtgttc ttgacgaaat tgagctaaag 91140
tagaaccatt aatggtttgt atgctccatt gccatccatc gtcaaaaata tcttcatcgt 91200
tataaagacg ctctttaact gaattccaaa tagcagtgta tggttcaaac cctgatttac 91260
cttcaacagc agcagtccaa atatcataaa aatgatttaa tccattagga gtcgtagtaa 91320
taataatttt cgaacgacga ccagatgaaa taactggttg aatagcaagc caggaatcat 91380
ggaaatttgg aataaacgcg cattcgtcaa tataaatcat tgcgaacgag ttaccacgaa 91440
ctgcgtcagg agaggaagca taggctccga ttgaggaacc attatcaagt tcaattgaac 91500
ccttattcca ttcaacaatt cctggttgta aaaagtcagg aagcagttca attgcttgct 91560
tagtacggtc taaaacttcc gcagacattg agcctttgtg agcaagaata cctacagctt 91620
tatccttgtt aaaacataca aagtgtgcaa ggaaaatagc tactaccgtt gttttaccga 91680
gctggcgcga tagattacaa acagtcatac gtttagatga cattattttg agcatatcac 91740
gctgataatc acgtaattga acctttatga caccatagtc aatatgagta atagcacagt 91800
atgtttctgc aaaataaaca atatcgtctc ggcatttttt ccattcctca accatttcac 91860
gagtccattg tgttttaata ttagctcgtt tcaagttagg aagacccata taccgagatc 91920
ttttattatt cttatcttta taagtttgaa ataattcagg cttatcagag ttatttggaa 91980
tttttactat tttgtgtaga cgaaggtaat cactgaattt ttcaggatac cattttccat 92040
cccactgaga ttttatccaa tgaattccat cttcatcttt tctttccgct aagcttgggt 92100
gttttattaa aatttttcca gcttcattta acggatggaa atcatttaat gcattaatcg 92160
gttgttccat ttatcacctt ctcacgagct tcttgagcct cgtaagcatc accaatttcg 92220
tccattaatt ctgttggtga acccatgaat actgtcgcat tctgaatatt catttgacct 92280
gtaggaacag cgcctttggt gccaacctgc tcagatgtaa tatctttcat atctttatga 92340
agcttcagta tttctctgtt cgtcgtagtc atttgcccca taagagttgc aaatacttcc 92400
atgtgacgag gagaatcagc attctttgct gtctcaagaa aaatcttggc cgcgtccatt 92460
agcatttgtt gttgaaaatg catatttcga cgaactacac cataatcatc ttctaagtca 92520
ggagtacggt tttgaggatt gcttttaact tctactaatt gcagaggttc atatacttta 92580
atttcctccc cgtcgattcc ggggaggtca gaaatatcta aaagtttgtt tatatcaaga 92640
ccttccataa taacctctat gttcttgggc caggaggttc tggcggtgtt ggtctattta 92700
cattgctagt gaaagtttgt tttactgttc catcccagtc ttctgggtta atatctcgag 92760
gaacaacttc gttatcgaca gattcaaaaa caccttcgcc atcaggcaaa tctcttgtat 92820
tggcgtgaaa atctgtataa gtagtacgaa ttaatccttc tgcatcatct accggaggat 92880
acatccatcc atttacttca aatgttagtg accattcaat tctacgacga gataaattat 92940
ctccatctat agattcgtct atagcagcag acatcagtac aattttaata tcccttttaa 93000
atggaatatc atttccaaac tgttcgtaca tagttgtatt aaaatgaggt tgaaaatatg 93060
gaagaatctg ttcaactatt tgaaacatat catcttcgta gcgagtaaag atactcaatt 93120
cataaatcat tttaatagga gatggattat actgcgatac tactgaagtt gcgccttttt 93180
gtagtaaatt ctgatttaaa atgtttgttt taaatggagc attatagcta aaatcaacta 93240
aatgtaaatt tatacgaggt agaatagttt caactttagc tacatcttct tgtgaattta 93300
tcgatgtcca tttattcaat ttcatcatga agtgttcctt tgatgcatac gtaataggaa 93360
cacgtataaa cttatcacca gattctaact gacgtttgat ttggatattt gaaaacaaat 93420
cgcccatcaa ggtagcatat cgtctaaaag acgaattata aaaataacca aacatgattt 93480
ctcctaatct gggctttaat tagtttataa tatttattaa tccatgaaat cattatcaaa 93540
tgggctagat tcgaaagatt tgcctctgtt attgacaaca acataaggtt caacatattc 93600
tttagcttca gaattaattt gatctacttc agcatactga tcaatattaa tatcatgaat 93660
accattaaga ttgcgaacag gatttaattc taattcactg aattctggaa tgttaattcc 93720
ttcatttttc tgtagaactg gattaatttc ttctccagaa taaatgaatt tacctgctgt 93780
aattttacga atagcgtttt ggcctaattg ataaaatgga tcatatggtt caacccagtt 93840
aatttcgaat aagctgttat ccataggaaa atatatcaaa tccccttcct tgggttcttt 93900
tccgttaact tggtgtttaa acaaatttgg attaatagac aaagttactt catcctgtac 93960
ttgcatacca aagttaccaa agaatgattt agctccttca tatccttcaa atgaatttaa 94020
atatgcagcg aatttccaag ctttagtaaa tttatttttt aagtcttcgc cgaatatcaa 94080
atcaggggaa acatactctc ttggaacata atagcattct acacctcgca tttgaatgct 94140
ttcagctact aatacatcag ctaatatttg gctgttttta taatgattga aatttacata 94200
aggatttagt atttcagttt cattagtctg agaataacca gtgcgatttt ctaatttagc 94260
aaaaagattt ttatcataag tagccatatt aacctaccaa aattccaaat ggaggatcga 94320
gcaagtataa ttcttcgcgt aatgcttctt tttctaatcg agcttcttct attaagcgtt 94380
gtccatcaat tgtaacaccg cctggaagca tcatgccttg gtgacgtgct aaaatttggc 94440
catttaattc tttagctaaa gctgtagcat agtctttcac ccaacgatta ttataagcac 94500
cttgcttaac atctgggtct tgacccacaa cacgacctac taaattatgg tctggattat 94560
tatatcgttc agataatgac caactatctt gcggaccaac tgttccatat cctactgtat 94620
ttccaaccat tttgtttgta tcaatgtatg atttagtcca gctttctacg ataatcaaat 94680
catatttttg gaagtttccc atgactttga gttgttcatt tgctgaattg aaccaaaagt 94740
ctggaatagg agaaagcata tcttgcatca ttcccatgta actggtaagc tgggtaaaat 94800
accctaaatc agctccaaag gcgtttggtc cataaaatct attacaagaa gtccccatgc 94860
caccattaat accagccatt cctaaaagaa agtcagtaaa ccatggatat gtagcgtttc 94920
cgtccattga cgttattgat ccaacatttg tacgtaaaat tcgagttact gcgaatacgt 94980
ttgaacctct taaatcgaag actccggtct tatatttttc ttcgtcatct cctacataaa 95040
atacatgaaa ccctttgtta agtccatcaa aatggtattc accgtataat tctagggcac 95100
gctggatgca atcatagatt tgatcgggtg ttaactcaac attaataatt ggagccccta 95160
aacgtcttag aatgacatct ttgagttcct ttggattttg agaattatat cctgacattt 95220
aaaaatcctt tggggccttg cggccccatg ttatgctggt gataaaaagg tagaaagtaa 95280
tacccattcg ccgtctttac gaacgtaagc ttgaccatct tttggagctt caggaatata 95340
acctgcttcc tgtaaagtct gaacatccgc ctgtaatgaa gatacattac ttttaatact 95400
acgcatttct tgattaatag aagaaatgtt agtttcatta gcttttattg aattagttaa 95460
tccacgttct tcgacagttg aaccatttgg atttgttcca tttactaatt tatttaatgt 95520
tacaacctgt cctttaattc cggaattgtt attaccaatt tcaacttgca agttttgaac 95580
atcattattc agtctattaa cggaagtttc aacagttgaa actctattta aaagagaccc 95640
aggaggagaa ggttgtccac cgctagaatc agttccaaca atttggttta accacgaaac 95700
gtttgctcgt agtccagatg aagtgttttc accaacaatt ccatttaaaa actcaataga 95760
tgttgtatta tctttaattt tacctttaat actagaagga atatcatctg agccaattga 95820
tgtttcaatg acagttaatc gctgtttaac acctccgctt ttatttagct catcagttaa 95880
agctgaaatt tctcgtgtat tagtgttaac atctgtgatt attgaagtat ttcctggata 95940
tccaatagaa gttttgatag atttaatttc ggaattaaga ttaatttgtg attgatctaa 96000
attatgcaca cgtgaatata tactttcact aaatgaaggt ggtctttgtc ctaattcctg 96060
tctaagattt cctacttcga ttgtaagcga acctacatca gattcaataa atttttcttc 96120
taaatcgctt agacgtattc cttgggaagt tatagcatct gtattattaa taatacgatg 96180
cttcattccc gtgctggtat ttcctacaac aggaagacca ttaatatctt gtccagcata 96240
ttgtcctagt tcccttttaa tccacaacaa atcatttcta atcgttctat aaactgaatt 96300
tgcttgcgaa ttaaatggac caatatcaga aagaatatta tcaaccgtag tatttgtacc 96360
atttaatata tcagtatgtt cacttgtgag cgtctttaaa cttgatatat catttttatt 96420
aacgctgatc tgtgatagcg cttctatatc tcctgataca tctaaaatgc cttgaatagt 96480
tttaatatct tcctgagatg tttcaatggc agttttaaga attcctacat tttcatcaag 96540
aatctcaaca tttttaaaca cggaaacagt tggtctattc attgatccat cgtttccata 96600
cttagtacta gctcctagta tttcttcacc atttttaatc catgaaatac gttcctgacc 96660
ttcgccagga acgctatcaa caaaaggtaa ctcttttaat tcaatcattt gtaatcctta 96720
gtaatgaatt ttaataatat agtttaatga tatattccat ggtctagttt cataaccaat 96780
taatccttca cgattaagtg taccaagggc atctctcggt ccacctaatt caaatccatc 96840
attagtgaag tatgaagcat tatcccagtc ggcatatttt ctagttccaa gatatccttg 96900
ataaacggac gcgccaaatg gagcttcatg tctttggtat tctccccagc caccagcatg 96960
tttatggtat gacatttgtt gtgcttgaac acctccaaca tgcattccgt cacatcctac 97020
gccaagtcta tcctttccat aaccatcttg tcctcgttga tttaaaatat gacctcctgt 97080
gccagctcct ctgacgaaaa gacctcgcat atcaggaatg ccagggttat tccaatcacc 97140
accaaatctc gttccaactg tgtttctata atcaggatat tgatctcctg acacggttcc 97200
accgtggcac ataatccaac ccggaggtgc agaatcaccc gcaaacatca taatagttcc 97260
aactggaacc ttttcagacg catatctttc agtggcaaca ggttgatcgc catttttcca 97320
cataccgccg cgtgaccaaa ttccatttgc tgtaagatgg tctaaattta aagaaccatt 97380
aatagtttgt ccaccgcgtg tattaattac atctgcgttc catgctaatg ctccagagcc 97440
atcaccctcg ggggcaatac cggcttgcgt cgttaatttt actacaccgc gcatagaacc 97500
agtagctcct cgaccattta atgtttcgcc tgttactgca acatctccca aattactatt 97560
aatttccgac tgcgttccta aacgtataac acccttatat tcttgtgttg caacggaatt 97620
cataaaggta tatggggaaa ttgcatatcc ttcgcgaaga gttccttgac gagtttgagc 97680
gacagtagat aattgaacta cacctctaac agattctgat gctgtgtctt ctgaaggagc 97740
tatttgtgaa attaatttta ttgcaagttt ttgcgttttt aatggagtca ttgccgtagt 97800
atcatcaact ccagctaaag ctgcaggtgt agatgatatt ttaataaccc cgtttgatga 97860
ctcagacgaa tatctatttt ggaacacatc gtcagtatgg tatttcagtt tttgcggcgt 97920
tattgatgaa ttattatctg agccttctaa tgtttcttca tttgttgaat agcgcgttaa 97980
accatattta gtttcagtag catttggata caataatctt gttgctaatg tagcaggtgt 98040
aacgatttta gaattattag ttccatctaa aacctcttgc tctgacgcaa tcattgctat 98100
tcctttaact tccatagttg catcaggaat accatttacg ccaatattac ttatttttga 98160
taatgcagac tgcactgtcg tgacagtgtc aggaaaattc gatccagtag gatcgaattt 98220
aacatatttt gattcatttg atacgtgctg atatgtattg ttactcatgc tattctctca 98280
aaataataaa atactgtagg ttgtgtgtga ctatctagcg taacagtttg cgcacctaat 98340
aattgccaag ttccataccc aggtttagaa ggagaaatta tttcttgttt gaaagtaatt 98400
cctttatcag agtattgttc taagatatgt tcttggttat ctaaatactt aacttgtatt 98460
ttatttccta tggtaggatg gtcttcaaat gaatcaattg caataaattt tgcaaccatt 98520
tcctgtagag ctgttctaac ggcactggta aattcgattg aagtcattcc attagtagct 98580
ttaacaggaa tgccaaacat gttaacaata accgggtcac ctggtttggc tgaagtatca 98640
gtaacagttc cttcaaatga ccaatagtct gtttgttgca cgccagtagg agatacgccg 98700
cttatattaa ctaatacagc tccaacctgt tgctctgcca tatttctaac atcattgata 98760
gcagattcta catttgggtc ataaaaacct tttgctattt gtgaaattgt tacagcacct 98820
actggctgat tattcataac cgaaatatca tttttcttag ttctaaaacc aagaaaatct 98880
gctaagcggg aaataactcc cgctttatta ttaagtaaac tcattatgca atccttatcc 98940
aacggtatac agtaatagac ggttgaatat tactaatatt agcaggagga gtatgtgaag 99000
agtttgttgt tgcgtagtct tcacgatatt ttgtatatat aggaccagtt tcgtctgggt 99060
catattgaca tcctccaata ataactgatc cattttcgtc ttcaattaaa actctttcat 99120
cagttttagt cgcaggaaga tttgcgtttt caagcgttac tgatgttgta ccaactgttc 99180
caccggcggt atgcgaagga tttccgctag aatctaaatc attattgttt aatgcaaagt 99240
ttggatctgt aacatcatca ttccatccta ctaaaacctg ccctttacca aataatttcc 99300
atgaaccaaa tcccatataa gtcaccggat tatttgggtt tatagcattt tcataaattg 99360
aaccaacagg ataaatgctg tcgaaaatag atgatattga attatacgtt ctagtataag 99420
aatcaacttt ttcaacattt ggccaaccga ttttatcaaa atctgttaag gctacatcac 99480
cagtaacttc agtagatgat cctttactaa cataacggtc atcagttaat tcaataatgt 99540
catctttttc taaaagagtt cctaaatcat tattgaacca tgttataacg attatatcgc 99600
cggattcaaa ttttctatca aataaaagac taacaggttt tccatcttca tattctatag 99660
aataatctgt attcgattct ttccattcac cgccaagaga tatacatcct gcttgcgtat 99720
ctgaattagc accttcacac aaaaacagag gatatccggc tgttccagct tgttgttgta 99780
aaattccatt aaaacgaact tcaagagaat taggattaat aggttctcca ggaattaatc 99840
caaatgcaga gaatggaatt gatttcattg ttgataaatc agtaacgtaa atacttcctt 99900
ctaaagaagt ttttgacgtt aattttgaat ctaatacttt tatttggcgt cttgtatatg 99960
aacttctcca ttgtgataca ccatccataa atgtttcaat ttgaacggtg tcaccaatat 100020
tacaaggctg tcttaatcga atgttaaatc catcaagagg aatcaattct ccttcatttt 100080
ccccaggaga gccaaagtca ctgttttcac taaatacatc gccataatat aattcattac 100140
cgcggtgttt tactcggatg ttattaacat tatagctagt tccacggaaa acatctaaaa 100200
agtctgtttg tccttgaact tcgactaaaa attctttacg tgctacatta ctaatatctg 100260
aactaataat tttgtcaatt tgtttgtttt tgacatattc ccaacgtcct ggagcacaat 100320
aaactaattc taaatcgcta aattgaacat taatttcaac tgatgacgat gatcctttaa 100380
tagtatcacc agaagcggct actagagtaa ctggattaac attccatgtt gcaaatacat 100440
ccctagcttt aattacttta ttataatcat taacggttcc tttaggaagt tgtagagtta 100500
ctcttccaga tgaagtgtta atggcatatg attttcccca ttctgctgtt agtgtttgtc 100560
ctgatgaagc attataagtt ttccaggcac cagctgaata tggaacatca ccgtcaccaa 100620
gctcgtaata aagctcatca aagttttcat ttatttttat accaccttta cgcaggtagt 100680
caccggtacc atcatctaca acattaccga tattaatatt ttgtttcatt attgagccac 100740
cccgattttc tgcgtagcga taactttaac tgctgctctc atgccaacaa tagaagaact 100800
tacagtcgct gttacataat ttgttttaat actaaatgca atattagcga tttcgtcttc 100860
ttcggtttca tttccaaccc gcatgacagc atattcagaa gaaattacct ctgaattaac 100920
agtatctaca agaatattta tttctgctgt tttaattttt cttccatcta ccgattggca 100980
tgtaactagc aatttagcca tattgtattc agtacgatga aatagtggaa tatcaactga 101040
cccggatgta gaaatattcc atgtaccttc agctggcgat tccttttggc caaacatact 101100
ttcaatagaa taattccaaa cagacgtaga attatcagat gaaatacagc gtaaagttac 101160
tttactatat ggactagtta ctactaaatt acctgaaaca ccttttattg aatcaatcgc 101220
ttgaatcgtt aaaggattag taactgatat agatccattt gagttaataa attcaacgca 101280
gtcaccaagt tcgcctcttt caatgataac tttaacacct acagtagagg tatcaatatc 101340
atgcctagtg ccaactttta ctggagttgc gtactctgca atagagtgtt tttgataata 101400
tccagtagca tgaataattt ggccatctgc tccagtgcca tttgctactg ccattttacg 101460
ctgatcgcca aacgcattat aaattgcgtt aaaatcacta ttaattttat taccaccgtc 101520
gaataagata tcaccagtag aagcgttacc aatttcgccg gtatcaatca atttctttgg 101580
ttcttgaatg aacatagcgg tttccttatg agtttatagt atttataaag aaaaagggag 101640
cccatgggct cccttaattt aaaatgtaaa cagaatattg atttcttctg tttgatccat 101700
tgccatgata ataggtggcc tattttccat ataaatcatt tcgcccgaat gcctcattaa 101760
atcttccgga tcataataat ccttttcagc tttaacgttt gggtcatttg gatgaacttt 101820
agcttcaaga ggattggtga ttattgatat ttgtctaaat cctttatttc ccggtaatgc 101880
agcatcagga aagtaaactg aatctaaata tgctttaaaa cggatagtat ttgccttaac 101940
acggtaaatt aatccaaaat catcttgttg ccaagtgaga ttatcttcat acccccatct 102000
agcagggtct tcttttaatt cctcaggcca aggaactacg atatattcat tcgtgcatct 102060
atttatagat acatcaggcg gaatctcaaa aagatattcc caaacataac cgtcgccggg 102120
ttcgattgtt ccttcagcgt ctcctcgacc ttcaggagga gtcattgacc taacagaagg 102180
agtccatttt ccacccaact taagacattc atccttatta gttaaagatg ctattgaaca 102240
cgttccggta tcaggaacat ctaaacaacg atatactaac cagcctgcgc ctgattcagt 102300
agcattgtaa ggagctgagt tacacactac aatatcgtta attctaaatg tgtatggatc 102360
cggatatcta gtatctcccc aatctctacg aggaataact gcatcaagca tagacggaag 102420
aacctttaca gttcccatca tatgagtcca catgtcagtt acacctaata cagaatcagt 102480
tggataaggt ggagcaaagc ccacctcatt ttcatttgat gaccacggtt ctgatcttcc 102540
aaatgtgata aagatagtgt ttttatccgg accacttcca attgaattat aaaaattcaa 102600
cattttttct gttctaaatt ttgaagtaac tatcgcacga tagataacac ttgaatcatt 102660
catctatttt aacctgtgtt ggattttcag ggtctcttgg atttcctata ttatctttta 102720
gacgtttatt aactaaatct ctaaattgcg caaatgttgt tccagatgcg tcaaatagag 102780
gactcattaa tttgcgtcgt tcagacggca attgaccttg aaatattgaa ttgttatttt 102840
cagtattata gtcatcagga agaggatatt ctacgccagc cattgggcca ggttcataaa 102900
ttgcttcgcc tgttaccgaa tcatgctcaa tttcaccagt cggagtcaat ttagctactc 102960
tatcagcata ttcagtaggc aatccagaat cccatttata gtttttgtat ttattaatta 103020
tagtctctgt atgtttaaga gttaaaccaa cattaataaa cattgttaaa agagtaattg 103080
ctataaatcc aaatcctact ggatgaacaa aacgaataac gtcagatttc cagcgggaag 103140
aaggcaaatt ggatttaatt ttcattacat aatatgatcg acttctatta atatagtcta 103200
tattattttg aagcaaatct tttcctttaa ccccgcgaat aatttcgcct tcgaaactag 103260
ggagtctttc tgctttaact tcttgaccgg caattaatct tcccaaaaga ttatgaatag 103320
ttacggtcca ttgcaattta ccattagaat agcttctttc tatataagta acattacatc 103380
ttcctgtagc tgtataaatc gtttgtccta ctaagtcttc ggtcaaagaa tcagattgaa 103440
cgattatatc atattcagta ccagccccag attcgatttc aatttcaact tcttcattat 103500
aaagaacttt aaaaagaaat ttgtatgatg cttcaattcc tttagtagaa taaaaatcat 103560
agctgcgtga ttcgaaaaat cttgcgacag catcacgttt gtcagcattt aaataaatgt 103620
ttcttttata tatctctgac cacaaatatt cccatgcatg ctcttctcgt ggatatttgt 103680
tacgaattaa atttcgtaaa ttgttatact gagttccata tccatcagaa agatattgaa 103740
tatatgcttc gcaaaatgct tcaaaattcg aatcctgcaa caaataagaa tcaggcatca 103800
ttgtgccaat taatggtctt aaatcaggat cagctaatcc atgctcttct tccggtgacc 103860
aaggagtttc acgctcttgg ttttgtaaaa atgcttttaa aaatattcca gttggcttcc 103920
aaattatttc aactgtgtct ctcactcgat agttaaaatc atagtaagaa attatttcac 103980
cagaagattt ataaaaaagc atcccagacg catatttttt aaatcccgtg aatttaacat 104040
ttggcattac tatcgtgcaa tcaccatcat cccagtattc atgaactaat ctatctggcg 104100
atgtttccgg aatattttct ataactttgg tgtattttaa atcagcataa actactacag 104160
ctctgtcaga gttgtttatc caacagcgtg tgttagattt tttagaccag ttaaagaatg 104220
gttctgcata gtatttcatc ggctgaggcg taaaagtttc ccaatcagat ttttcatctg 104280
ctataaatgc catcatatga taatgcttat cagctagcca ttcacgagga aattcatatt 104340
taacagcacc gattaactga tacttcacca cagtttcaga gtcattaaca atattatcac 104400
ttaaaaattt aaaattactc gaagatagag aaactaattt accatcagtt gacatattcg 104460
catatcccgg ttgaatacgt cttctttctt cttcagtgtt accaaaaact cttttccatg 104520
ttttcgtgcc atgatttaaa acatatattc ctttatcagc agaatcaatt atttttgatg 104580
ttctaggatt agcatttaat gtttcaactt ctccaataat aagagcaaaa actttatcac 104640
caatagaatc cattttataa catactgctt taggatttcc ggttatagtc attatatcag 104700
gttcaaatag cctttccgaa tatgttggag ataatgggtc agaatctatg ggtgcattac 104760
tcgtttttat gtatctaact ttgtctctgg cgacaacgta aatgtaatca tcggtgcaag 104820
taatagcttc tgcaatgcgg tatacattag ctggcaaagt cgcgtaagtg gcaaaaattt 104880
ctacatcaaa tcctagatgt aattggtcgc caagtttagc aaatgttata tcctgcgaac 104940
taaatctgac atcgtcagct gaccatctga catcagtaga tttgcggcca tagaaaatct 105000
tgtcgtatcc tagaacgtat gttgtgttcg cagattggta atataccgtc ttagataaag 105060
gatatcctac acggtcattg aagagcttta cagctttcca agtttgtcct ttatcattgg 105120
atactttaac tacaggttga tagcgctcaa aaaggtataa aatcccttct gattccatca 105180
aataaactcg gttaatatcc ttacatactt gctgaataga accttgtatt tcatgatatt 105240
cattttcacc aataataaaa ttacttattg atgaaacgtc aacatatgat gggctgaatt 105300
ggaacgattc attcatcaat gcagccatta tagtgtcatt attaaaatta acatagttag 105360
aattattaag agtaaatttt tcctgaatga atttattagc taattgcatt tcaatcatat 105420
tttgaaatgt gtaagcattc gtagcaaaag tttcaaactc ttcggtataa atccaatcag 105480
actgctcaaa atcttgcgca gctgtagcta ctctaataat gtacgatgtc aatggattag 105540
cattatcaaa aaagaagctg ttatttgcag tatatcctaa gttaacccat ctgtattgat 105600
tactcgggag attttccccc gagtctgttt ttgtctcagc gatttctaca aaatagtaga 105660
aattagcacc aacgtcatcc cagcgtactt gcacctgatt tgcggataac ttggaaattc 105720
tgagactagt gactgaaggt gcttttactg tcattgtgat ataggctcca aatcgatagt 105780
taagtattgt ggacgtaagt cattttcaaa tacaatcagt gaaccatcgc gagtaaagat 105840
aacatcatcg gttggatcag aatataattc aatagtctga acttcaaatt tttcagatgt 105900
taaattaatt ttagcgatat tccaataaat cacatcagct ggataattta tttcaccgat 105960
aacatagtat ttgtcgcgtc catcagaatt tgctaatttg ttaaaatcgt tgcctgtata 106020
tggctgaatg ttttcatttt ctgtaacatc gccagaagca aatggaccaa taataacttt 106080
accaattcct ttagaatctc ggtctgttga tactatgcga acgtcatata atacatcttc 106140
ttctaaacca gtatcaggat ttacaacctt tcgtccagaa ttaaatgaaa acgtattaga 106200
ttccatagaa cgatctttta tttgattatt gtatttaata cctgcttcag gcgttttata 106260
gaagttttgt acttcacgaa caatttgaat tgtcgctgat gaaccaatga tagaatgatc 106320
tgcatcatct acatatgtca acatcttaga tttagcgaaa gatgagttaa aaatttctac 106380
atcttcggta taataacgat caattttatc aattatttga ccttcgagcc actgttcgga 106440
ttcttgcagc ttatttaaag catatgtgac ttttaaatta gtcttaataa aaagataatt 106500
aggagaaata attgacggtg taataggagc taaattatag tctttgagat aatttttaat 106560
atcttcgcgc tgtacagtag ttaaatatag ccctgattta ggtttagcag caataaatgc 106620
ataaccaggt ttagtagaat cagtgaaagt ctgaactgct tgaataatag aaccaaatct 106680
ctctgaaacg aatgtatcat aatccgtcgc agttacgcag cgttgctggg tctcgcgttt 106740
aatagtaccc aattcacgaa tacgttcaat atcttctgga tcaccgccgc catctgcccc 106800
aacaaaatct gggtcatcgt ttggattttc attaatattg atgacagtta tatttgttaa 106860
tgtatctgca tatgaaaatc cgactgcgcc attcgcatct gcgccgttag tactgatgta 106920
ctcaataaca atcgtagagt tctgggtagg tttaagacct ccaatataat tagcggttaa 106980
tgctccttct gcggcattaa cagaaatctc accttcacca aaataaaatt cggtattccc 107040
atcaatagtt tcacgcatgt agtaaattgt cgatgtagaa ccagcatgaa ccattgactt 107100
tcttgtccag ttaatccatt ctgctccatc aacgtatagt ttaacttggt ttctatctat 107160
atttttgtca taaatgataa taggtgttaa tttatcgtaa atgatttcag ttcttactat 107220
acgtccctgg gctaatttta aacgcggaaa atattggtta tttttatcgc gaatagcaat 107280
aacatcttcg gtagatacaa agttgtaagg attaacggaa gtatcttttg catatgctaa 107340
aaagcgagta ccacgaggaa tagtaatgta atttctattc aatgcgtctg tacaagttag 107400
cataatttca gtttgagcag ctgattttga agtaggtaaa tatccattat cttgtgcagc 107460
ttgaactact gaactacgca aattagcagt acgcataaag ctttcgtaca aggcagcatt 107520
accaaactgc tgaatgtata atgtattata agccaaaagg tcacacagaa cgtttaatct 107580
tgagccttca aaatcataat ccaaaaattc attttggcca ttaagccatt caatgaggtt 107640
ttgttttatt tcagcaaatg tacccccgac gaatatctcg ggaatagcat ttgctgttct 107700
tgttaattga taatttacag gggtatttgc cattttaaat cctatttaat gaatacttta 107760
gatgatgcct gagccacagt atcaccgcat gatattggat cagccatttg aacagctttc 107820
tttccagtga catatacctt agaagttcta ggttgtgtca ctccgccatg tgtttcatat 107880
ggctttttaa tttctgtatg ttctgtaatt ggatcacctg ctacgagaac agcaattcct 107940
ccagtgaata ctttactttg cgtagcattc acaactgttg gaggccatgc ttcatggccg 108000
gaagtaacac acttatcata acttaatcct gacatttatg gcctctcata cacatagctt 108060
ctcaatttat tagcccaacg actccaattt ccaactatag tttttgtgta atttttaaca 108120
agagtttttc ttattggagc tggaggattc gttggttcag tagtatcaga agatgaccta 108180
gaattactgc cagaacctcc agattcacct tgttcttggt agtcatatat taatgttact 108240
tcgtaagtga atgtcttctg gaggttctga ggagctttcc ataaatacaa ttgggtatta 108300
gaatcagttg gaaggtcttc ccatgaagca gcagttttaa attcattatc taaacgatat 108360
ttcaacgcat catttccaaa tccaaacaca gattcatacg ttccatataa acgattttct 108420
tctactaaaa ccccaggagt ttcttcgtaa ctagttatat ttatagatac taacgtttca 108480
cctgtttcta attgagcggt aaaggtgacg tcgatagaag aaccttccat ggattctcct 108540
aaatcagcgc tcattggaag tatattagcc aatgtcaatc ctcgatccat caattgtgta 108600
ttgaccagat gaaatagaac tcatagatgc cattttttct gtccaatcac caccaacgtc 108660
ccagtcaact gtcccagcaa ctttccaaga aagatttcca tttactgtat tagtctgatt 108720
tccttcaact aaagtggtag catctccttt aactgtaatg tcagcattac cttcaactac 108780
aatagtaaca ttacctttaa ctaggatagt tccattacct tcaaccgtct tagtttcatc 108840
gccacgcaca aatattgtat tgcttccatc tatttggtgg agacgattat ccatgttgta 108900
ataaatttct gatccaccga cgttagtctt tttatcgccg gctaccaaaa aattaccatc 108960
agcatttgtt atatcataca aattatcaac agtttttctt gttcttcttc ctgacggtga 109020
tacttcctca tacgttccag tcggatgaac taatctatat cgttcttgcc caggggtatc 109080
atcaaattcc tgaatatgac cgctttcagt ttccattgtg tgaacatacg gatattcgcc 109140
tttatatgaa gaaacaggtt ctttaaataa aattctcgaa tcatttggaa taggaggatc 109200
agctgggtca gaagactttg ctacagtagc agccattgct gacaaagacc tagccggtgt 109260
tttcacttca ataccgtatg attccaaatt acctgtaaga ataatcatgg taacacgaga 109320
tgcacggcct tttgtttgtt gataccacaa tgaatcacga ccagctttat atgccttttc 109380
ccaatctcct gctaacatag cagttaacat tgtgttaaat ttagctacac caccaacacc 109440
catctgaaat gccatatttt ctaatgccat ttgacgagaa cgattaactg cttgccaaac 109500
tgggccaact ttagaatgcg atttaatgtc acgttgcata tcagccaaat cacgttcaaa 109560
taaagttacc gcttcttcca ttgtaataga acctggattt ccggtaattt cacgaccaac 109620
ttgttttgat aaaactttat taatttgagt catatcacga actggctgct tcatgataag 109680
atgaccaatg ccaattgtcg gatatccttc agtatcccaa taaactttta gtcttaatcc 109740
ttcatcacgg cgaagcattt cagccattga catatttgga ttatcatcag ttggaatttc 109800
tgatagcggt ctatcatcag gatttatcgc agtatctaga ttactgtctt ggataatatt 109860
agaagacgaa tcatatccta cttctccgcc ttggtttaat acgttagtat catttcctag 109920
acgtctagga tactgtccag tcgggtcaga aaatccttca agtctattag gcttttcgcg 109980
aactattcca ccatacgtgc caaggacaat tccgttagtt ttccatttgt ccaaaaaatg 110040
accataaact ctagttcctt ctaccggacc agtaactgag cctccaattc cagacattgc 110100
tgcagaagtt ataggttgaa taactgacat ccatggtaat ttatcagttg gaatacccat 110160
tacgtcgcct tgtgctcttt gaggtggatg cagaccaacc acacgaacac gaacacgacc 110220
taattttaat gggtccattc tatcttcaac aacaccaaca aaccaattaa ggttattact 110280
tatcatttcc ataagatttc tccattatac gtataaggtc gttcataaat gaattgatgt 110340
ctgattttgc tattattttt atttgacgaa gtttttcatt ttcaagaaca gcagcttcat 110400
acgtatcgac cgcagcaagt gctccttcat attgaggata ttttctagct ttatcacctt 110460
tgtcatacca aacatatgga ttatcatcat atgatattaa attataaaat ttttcaccgt 110520
tctcattcac atgatatact atttggtctc cacctacgtt tttatatttt tgtatagatg 110580
cttgataagc agcttcttgc gaagtaatcc atccataata cggatcataa ttatcattac 110640
acatcaataa aacccaatac aactgcggat ttccatatat agcatttgct aattcttccg 110700
ggcgtggtga acctttaata taataagtgc gtaagcggta tcctgcaaga gcacgtttga 110760
aatagtcttt atagtttcta aaaatatctg tcataggaat agtcggcgcg tttttattca 110820
ccgttttggc cgcatattca atcggatcaa aaaatgtaaa gagcatgggc cctcctgttt 110880
ataaatatat tatctattta taaggagaat ccaatggcat attctggaaa atgggttcct 110940
aaaaatatat caaaatatag aggtgaccct aaaaaaatta cgtatagatc aaattgggaa 111000
aaattctttt ttgaatggtt agataaaaat ccagaaatta ttgcatgggg tagtgaaaca 111060
gcagtaattc cttatttttg taatgcagaa gggaaaaaac gtagatactt catggatatt 111120
tggatgaaag attcttctgg acaagaattt tttattgaaa taaagcctaa aaaagaaaca 111180
caaccaccag ttaaaccagc acatctaaca accgcagcga agaaaagatt tatgaatgaa 111240
atttatacat attcagttaa tactgacaaa tggaaagcag ctcaagcttt agctgaaaag 111300
cgtggaataa aatttagaat tttaacagaa gatggattac gagctcttgg ctttaagggg 111360
gcataatggc tatttttcaa ataattaatg aaagcactcc ccaagttcca aaggttaagc 111420
aatcattaaa cgaaaagaaa tggattcaga taggtcttga atacaaaaag gccaaagcaa 111480
aaggaatgac aggaaagcaa tttgctgaag aaagaggaat caaatactct acgtttactt 111540
cagcaatgtc aaaatatgct tcaggaatta aaacagccga aaagattcaa aagcttgaat 111600
caaaaccaat gaataaactc aataagcaag aaagacaact gcttatgata aattcattca 111660
ggcaaacatt gcgtgataaa attcgtaatg aaggcgcagc aattaataat aaaaccagaa 111720
agtggtttgc tgaaactatt aagcaagtaa aaggacataa agttgttcgc ccgcagccgg 111780
gacgaatata tgcttttgct tatgatgcta aacacaagga aactcttcct tactgggata 111840
aatttccttt gataatttat cttggtttag gtaaacataa tttaatgtac ggattgaact 111900
tgcactatat tccacctaaa gctcgtcagc aatttctaga agagctttta aagcaatatt 111960
caaatacacc tactattact aataaaacga aattaaaaat tgattggagt caagtgaaag 112020
gatttagggg tgcagaccaa atgattaagg catatatacc cggtaatatt atgggtagcc 112080
ttgttgaaat cgccccgaaa gactgggcga acgttgtgtt aatgccgctt cagcagttcg 112140
tttcaaaagg aaaacgtttc tctgcaaaca aagtctggtc aaatatctaa ttctattatc 112200
ttccattctt ttctattgtt tgttctaatt ggaattgaat ggaagggact tagacccatt 112260
ataccaccaa catttataaa gcattatgag gaatatatgt cgcaagcact gcaacaaatt 112320
tttaaccaag caaatacaac taactttgta gtatcaatac cacatagtaa tactacatct 112380
gcttttactt taaatgctca gtcagttcct attccaggaa ttagaatacc tgttactgat 112440
accgtgactg ggccgtttgg actaggcaga gcacaacgtc caggagttac atttgagtac 112500
gatccactca tcgtgagatt tatagttgac gaagagctta agtcgtggat aggaatgtat 112560
gaatggatgt taggaactag taactatctt acaggcgaaa atactgccca aaaaacaggt 112620
cctgaataca ttacgcttta cattttagat aatagtaaaa ctgaaatcgt gatgtcaata 112680
aatttttata agccctgggt ttctgacctg tctgaagtag aatttagcta cacggaagat 112740
tcagacccag ccttagtatg cacagcaacg attccttata cgtattttca agtagaaaaa 112800
gatggcaaaa ttatagcaga agtttaatgc ttcagtttca tgtgttataa tcttaactaa 112860
atttgaggag aaacatatga aactaatctt tttaagtggt gtaaagcgta gtggaaaaga 112920
tactactgca gattttatca tgaataatta ttctgcagtt aaatatcaac ttgctggtcc 112980
tattaaagat gcattggctt atgcatgggg cgtatttgca gcaaacactg actatccttg 113040
cttaactcgt aaagagtttg aaggaattga ctatgatcgt gagactaatt taaatctgac 113100
taaattagaa gtaattacga ttatggaaca agcattttgc tatcttaata gtaaaagccc 113160
aattaaaggt gtgtttgttt ttgatgacga aggaaaagaa tcagttaatt tcgtagcatt 113220
taacaagatt gctgacgtta taaatactat tgaagatcaa tggtcagtcc gtcgtctgat 113280
gcaagcccta ggtacggatt tgattgttaa taacttcgac cgcatgtatt gggtaaaatt 113340
atttgcttta gattatcttg ataaatttaa ctcaggttat gattattata tcgttcctga 113400
tactcgtcaa gatcatgaaa tggatgcggc tagggcgatg ggtgctacag taattcatgt 113460
agttcgtcct ggtcaaaaat ccaatgatac tcatattaca gaagctggat tgccaattcg 113520
tgatggcgat ttagtaatta caaacgatgg ttctcttgaa gaactttttt ctaaaattaa 113580
aaatacacta aaggtactat aatgtctgaa caaactattg aacaaaaact gtctgctgaa 113640
atcgtagctc tgaaatctcg tattcttgat acgcaggacc aggcggctcg tctgatggaa 113700
gaatccaaaa ttctgcaagg aactttggct gaaattgctc gcgcagtagg tattactggc 113760
gatactatca aagttgaaga aatcgttgaa gctgtcaaga atcttactgc tgaatctact 113820
gatgaagaat aatggaattt aaagactttt caacgggtct ttatgtagca gctaagtttt 113880
cagaattaac acttgatgcg ctggaagaac tccagcgctc tttacgtgtt cctaatccag 113940
ttcctagaga aaaaattcat tcgaccatat gttattcaag agtaaatgtt ccgtatgtta 114000
catcaagcgg aagttttgaa gtagcttctt ctggacattt agaagtatgg aaaacacaag 114060
atggatcgac tcttgtactt gtgctagatt ctgaatatct gcgctgtaga cacatgtatg 114120
cgcgggcact aggtgctaca catgattttg atgattacac accgcatata acattgtctt 114180
ataatgttgg acccttatca tttagcggtg atgtacaaat tccggtcgta ttagatcgtg 114240
aatacaaaga gcctcttaaa ctcgattggg cagatgattt aaaataattt cacaaagttg 114300
tttacatgct gatgaggtag tgatactatt atctcatcaa aattaattag gaaaataaaa 114360
tgaaaacttt caaagagttt gctacaaaaa ctactatcac tgaatcttct cacggtatgg 114420
aagtaaagct tggaatggct ttagctgaag ctgaacgtct tttctctcgt attaaagaac 114480
ttgcagctgc agtcgatcct tcatctttta aaggagatca aactaaagtt aaagcacttt 114540
tagcgttatg ctccgatgca ggagaaattg ctaaaaatgg ttctaagatg aagaaacgat 114600
tagaagattt aaaataattt cacaaagttg tttacatagg gttttagttg tgatactatt 114660
accctatcaa ctaccgagga gaataaaatg aaacgttgtg aattaattcg aaatgttgct 114720
attgcaattt ctgcttctgc ttttagtttt tcaatgtttg ttggatttat atgcggatta 114780
ttgactacag cagaaaatgt gttttcactt gtagtagcat ttttaattgg tttaattgct 114840
atcgttatgg ataaaatttc taaaggtgaa tagaatgtac aaagtgtatg cggattatca 114900
ggctaatcca tctgaaaagc caggttgtca aattggatgg gctcatgata ctttgcttga 114960
agcagtagat gctgctcaaa aattgggata taaatatgta gagattgttc aacttccatc 115020
aggaacagtt attactctcg aagagttcaa taatattaaa ccaaactttt tactttttgc 115080
aggtgataat tattatcctc gcggtggata tgctgattta atcgcgaaag ccgctaccga 115140
agatgaactc cgtgatatta tcaaagaaaa tgaaaacaaa ccgatgtatg gttctaatcg 115200
ctttgattgg tggcaaatcg taaatgccca tactcatact attgttgatg aaggttgata 115260
atgattcttt atgcgaaagt atcgtccatt gaaaatggat ataaatatga tcaagacgcg 115320
gctaaagcct tgattgatga ttatggcatt ttaacatgtt ttgaagttga aaaggtttac 115380
attgaccgtt catcttcaca agttaaatta gtgaaggaag accgtaaatt taatacagta 115440
aattttgatt tctttattga aacagaaaaa ggtcctcttg aatatgatat tttcaagaat 115500
cctttgggtc ttgaatgcat cgtaaatatg tatcatcata aatggtaaat atgctttaag 115560
aattatttgt tattattaac tcatatcgca ctgattaata ccctctatca tcaagggttc 115620
ttgcttgaga gcctttgtta ataattggga atcatattat ggatactaaa ttagctgaaa 115680
tttttgaagg aaaacatcca aattttagta caggaaagct gaaagacaaa ataataaaag 115740
aaaatatttt tccatatgag tgtgcaattt gtaaaatttc aaaatggcaa aataagcata 115800
ttgttctgca attagaccat attgatggaa ataacaaaaa tcatcttaaa tcaaatttaa 115860
gattattatg tccaaactgt cattcgcaaa ctgatacttt tgctggtaaa aatattaaaa 115920
ataataaaaa gcgttataat gttagtgatg aagaaatttt aaacgcatta ttaaattcgg 115980
ctactatatc atctgcaatt acttcattag gtttaagtaa aggcggaaac tataaaagat 116040
tcattaaaat tgctaatgat aacaaattat atcatttact ggtaaatatt aatgaaaaga 116100
ttttaactga tgaaatttac gaagaattag ttaaaatcga ttattctaaa tttggatggg 116160
ttagtaaagc tgctaaaata ataggtataa gcccacaaaa agctagaaaa tggatagaac 116220
gaaagtgtcc agaattgata gaacagtctt tttcacgtaa taaataatat agcgcgagaa 116280
tggtcaaatt ggtaaaggca cagcacttaa aatgctgcgg aatgatttcc ttgtgggttc 116340
gagtcccact tctcgtacca aagtttgcgg atatcgtata atggcattac ctcagacttc 116400
caatctgatg atgtgagttc gattctcatt atccgctcca atttaattta ctccgtgtag 116460
ctcagtttgg tagagcgtct gctttgggag cagaatgtcg caggttcaaa tcctgccgcg 116520
gagactggag gcgtggcaga gtggtttaat gcaccggtct tgaaaaccgg cagtcgctcc 116580
ggcgactcat aggttcaaat cctatcgcct ccgtaatttc gctgatttag ctcagtaggt 116640
agagcacctc acttgtaatg aggacgtcgg cggttcgatt ccgtcaatca gcatatcaag 116700
gccctgtagc tggaaggttc aagcaagcga ctcataatcg ccagatggtg gttcaattcc 116760
acccagggcc atattttgag aacataaata ctcttagaaa taggagatat ttatgttcca 116820
ttacatttat aaaataacaa ataaaattaa taataaaatc tatataggcg ctcattctac 116880
cgaaaattta gatgatggat atatgggttc tggtaaatta ttaaaaagag cccaagataa 116940
gtatggtata gaaaattttt ctaaagaaat attagagttc tttgacgata aaacctctat 117000
gtttgagtca gaaaagaata ttgtgactga agagttttta aagcgccctg atgtttataa 117060
tttgaaatta ggtggtgaag gtggatggga ccatataaat attcctggga tgctaaacca 117120
gaagaaagac gctagtttaa aaggagctaa atcgtttaag tcacgtttta aaaatgatat 117180
tttacttcaa gaaaaatatc gtaaacatgg ttcaaatgta tttaaacgct tgtggtcaac 117240
tcctgaatac agggaaaaat ttttaaataa tagcagattt ttaaataagc atcatactcc 117300
tgaaactatt aataaaatga aagaatctca cgccagaaat aaacatcaac agggcgaaaa 117360
gaattcccaa tttggtatga tgtggattca ttcattagat gaaaaagttt ctaaacgtat 117420
taagaaaact gacccaattc cagaaggatg gtttaaaggt cgaaaaatga aattttaatt 117480
acgaggcata gctcaattgt atagagcaac ggacttctaa tccgtaggtt gaaggttaga 117540
atccttctgc ctcgaccaaa caagaagccg ggtcgctacc ggtaagtcgt cggactgatg 117600
ttccctgggt aaggactggc attaacaaat ctttacgatc tgttaatgtc cccttacatc 117660
acagcagaaa cggcgcacag aattatcgat tcgaggaaat atctttgccg taagccgagt 117720
agcgtttttg acggaacgtt cggatatggt cgagatatgg ccttttaaaa atattgagta 117780
gcgtcaactg cttaataacc gggttcgaat cccggcgttt cgtacaaaca cttgccttag 117840
caggtggaac cccgacaagg ttgccgcaag gcttagcccc gaccgaaagg ttggggcttt 117900
ttagtataaa tatagtagta tattaaatcc acgaattaaa acaggaaata agatgaaatc 117960
atatgctcaa tttttaaatg aagcggtgtt aaatgaagca tctagcaccg aaattcaagc 118020
tgtcgcaaaa gcagccattg cagcgggtaa atattcctat aaagatgctt ctgacgaatc 118080
acgattccaa tttgctcgcg acatgaaagc agaaggattt acgggaaatg cagttagtat 118140
ggcctggaaa agtttagttg ctactggcgc tgcttttgca aaggcttcgg gtaaacctgc 118200
tcctaaagca gatcctaaag ctgcacaaga aaaaaatatc gttaaaggaa ttatctctaa 118260
atatgaagct atccttaaag agcttttagt aatcaaaacc gaaggccaaa agctagcccg 118320
tgcttatagt ttcaaagata atccgcatgt tcactctctt gagtatgttg aagacatcca 118380
aaaaattatt aaagaccgca tttggtctgc taaacagatc aaataacatt cttaacccca 118440
gccgaaaggt tggggctttt tggtatctag gcctttctgg acctctctag tcatcatttg 118500
gtttataccc tttataatat attatcctat cttttaattg cccctccctg ccctagaatt 118560
ccctaaaact ttttaaaaaa tttttcacaa aacggtttac atctctgttc ttccatggta 118620
ctatacaact atcaactact gatacagaaa acaacttgga gaatgaaatg gataattacg 118680
gcgaactgtt caacttcttt atgaaatgcg tttcagaaga tttcggtcgt acagtgaatg 118740
atattaaagt tatcggtcct gatcatccga tgtttgaaac ttacgcagta atgggtaatg 118800
aagatggtca gtggtatact gtaaaagttg tgattaacat gttcactgct gaaggttatg 118860
ttaaactgtc ttctaaagtt taccatgata acgacgaaat cgcagaagaa tatttcaata 118920
atatgaaata agtttacaca ggctcatgat tgagatatta tgagcctgta acttgaggag 118980
aacataatga atattgaaga taaagaaatg cgagagttat ataattcatt aacacccgaa 119040
caacaaaaag ctgccaaaga attagagaaa gctcttagtt taagcttgac aaaaactgat 119100
tgggccgccg tgtatgaaga aaaaatgagg tcggaaaatg aagctatcga gagaaatgaa 119160
tggattgtgg ataccaagat tggagctgat ggttgttctg ttgaggtgtc agctgtagtt 119220
aaaggtactc atggcgaaaa atcatggggt tggcataatg aggcaaacaa atatattgtt 119280
ctctcaacat caaaaactta tggtcaaaag gttcctgtat ccaaagctat tattaagcaa 119340
gctcaatggg aagccaatga aatctgtctc gcaaaaatga aataacatgt ttacatttct 119400
caaataacag gatataattc tacacggatt ttaaatctta atcaacctaa ggaaatacta 119460
tgaacacact gaagaaaatt gttgagttta ttcgcactaa acttggttct gctatggcta 119520
aaaatttatc tgttgaagaa cagtatactg ctgcggcagc aaaactactt gataaaatta 119580
aagatctaaa aactgcttct gttaaatcta ttaatgaaga aaaacgtatt cgtgaactta 119640
ttgtcgaaaa gaatcgacag gctgaatcaa aagagcgtga aattcgtaaa cttctttccg 119700
aaggtcaaga tgtaacaatg catgctaaac tcggtttact atatcgtcga acagctgagc 119760
agttgactac taaagctgac ggttatgctg aaatgcgaat tgaaatcgcc aagaaagtag 119820
ttgagttaga tgatgctcgc caagaacttg cagttaaatt ggaatatatc cgtgaaactc 119880
gtgcagcaaa tgcccttgga attagtactg ccgatgatgt agttgaaatt gcagcactga 119940
ctaaggttga tattgaagat actcttgctc gagttgaaac ctttaacggt aatatttctg 120000
gggttgaaac tacctctgcc gatgttcagg aatacattaa ttctctgaaa taatgataag 120060
gggcttcggc ccctattact tggagtaaat aggaatgaaa atgcaaagtg atttcaattc 120120
aatgtttgaa gagttccaaa gacaggttga tgttccagac caattactaa atgctcttaa 120180
acgtatggca gaaggacgta attattattg ggggtcttca tatgaaactg atgaaagtct 120240
ttctggattt tataaaggta aaaagtcttt aatacgtcct ggaatactta ttaacagtat 120300
tgaatcaatt catttattga cgtgtgattt tgatgttgaa tttactgatt ttgtttctcc 120360
tgaatggaca gtatgttatt taaacgacga ttatgattat ctcggcattt atagtttaag 120420
tgacgcatgg tttaaacgta acttacaaaa gtcaaattta ttctatattg atactacagt 120480
aaaatttcag ggaaagaaat atttctttac tcttatagtt gattctgaaa cgaagcatga 120540
aaataaacgt attcttagta aaaagaatat cttgactatt attgatgatc tttttgataa 120600
attcgtagaa aatcctaatt ttgaaagtga tttattatta gaaaaatttg ttaaggaatg 120660
tagagaatat gtcaaagcca tcactatacc ttccaagtaa acctttgaag tatgaactaa 120720
agcgccagat aatttctacc gatgtattaa taggtcctgt tatactcata tcatttgtaa 120780
ttctattgat tattggaggt gttttagatg ttatgactga tattgattct ggcgaaatac 120840
ttgtgttaat gctaattctt ccattaatag ttccactttt attagtacct ataaattggg 120900
taggatactg gtatcaagga agacattatc gtaaacgcgt acgtgattgg aaagcacagt 120960
gtaaaaagat taaaaaggaa catcagctta aacttgctgc atatgaattt gatgaaatta 121020
tgaaatttgt taaggaatca cgatgcaaaa gccaaaacta aataaagtca aatattcgtt 121080
ttctgagtca tttttaattt ttgctgtggc gttggctgca gctcttgcgg gtagtctttt 121140
tggattgtta attgactgtc ttattttaaa catcgacggc acagtaaata taacagaagt 121200
ttggagtgag ctttgttata ctaaaattat ttcattattt tcattctttg gtatcatttt 121260
atattttcat tatgataatt ttaaaataaa ttggcaaaga aaaaaggatt acaaaataca 121320
attaaaggaa tataatagct acatgtctta tattgaaaaa gaatcaatgg aagagtttgt 121380
gagtgattgc aggaaaatca gatgatttta aaaactcgct ggtatgactt agacgatggg 121440
gatgatggca ttccagttga tagagttgac tggaatggtt gttctgaaga tacaaagaaa 121500
cgattaatta gggagtttag aatgggatat caagcagcta agccatttac tgtaacagat 121560
gataaattcg tgtgtattca aaatggtcgc gctaagttaa cgaatgctga ttggttcaca 121620
gataagaagg ttcttctgtg gtatatcatt agtcttccta tatcatcgtt agtattttac 121680
ttttttataa aaaatccaat ggacagaata ggagattggg ttcttttaac tatacttgtt 121740
aatattttta cagcagcagt attatcagga atatggcgca tgttcattga aatgccatgg 121800
cggttacgta ggcagcaaaa gatttttgat gaaaagaaat atactcaaaa tttaaataac 121860
tttatcactg aatgcaggaa attaaaatga aaacattatc agctggtatt atctttatga 121920
cagaagataa agatttattt atgggtcggg ttactggttc tcgtaagcct ggaatgatgg 121980
cacatcgctg ggatattcca aagggacgtg tagaaagttc tgatttgaat gcactggaag 122040
ctgcaaaaag agaatgctta gaagagaccg gttttagcaa ttataatcca gaccttctag 122100
aagacctagg tgtatttaaa tattctagta ataaagactt acagttattt tattatacga 122160
ttccagtaga gcatgagatg ttcagaaatt gccattgcga gtcttatttt gaaaataaag 122220
atggcgttat gattccagag atggacgctt ttgctcttat tcctcgtacc cagtggcaat 122280
atgtgatggg cccttcactt taccgaataa tgaacaacct cttttaattt ataaatacct 122340
tctataaata cttaggaggt attatgaata tatttgaaat gttacgtata gatgaaggtc 122400
ttagacttaa aatctataaa gacacagaag gttattacac tattggcatt ggtcatttgc 122460
ttactaaaag tccatcacta agcgttgcta aatctgaatt agataaagct attgggcgta 122520
attgcaatgg tgtaattaca aaagacgagg ctgaaaaact ctttaatcag gatgtcgatg 122580
ctgctgttcg cggaattctg agaaatgcta aattaaaacc agtttatgat tctcttgatg 122640
ctgttcgccg ctgtgcattg attaacatgg tcttccaaat gggggaaacc ggcgtagcag 122700
gatttactaa ttctttgcgc atgctccagc aaaaacgctg ggatgaagca gcagttaact 122760
tagctaaaag tagatggtat aatcaaacac ctaaccgtgc aaaacgagtt attgcaacgt 122820
ttagaaccgg aacttgggac gcgtataaaa atctataaag ttgtttactt tctcctagaa 122880
ttgtgatagt atattcacag ttacttggag ggataaaatg actcgtatta atttgacttt 122940
agtatctgaa cttgctgatc aacatttaat cgcagaatac cgtgaactgc cgcgtgtttt 123000
tggtatagtt cgtaaacatg ttgcaaatgg taagcgggtt aaagatttta aaatatcttc 123060
cgagtttatt ttaggttctg gtcatgtcac gttcttttac gataagttag aatttttgcg 123120
aaagcgtcaa tcagacatta taacggaatg cttaaaacgt gggtttagta taaaagatac 123180
tgaagttcct gacatcagcg atattccagt agaatggaaa aatgattata atccatgcaa 123240
atcagctatt aaattgagtc aacaacgact cgatgaaaaa attttaatga agccacactg 123300
gtataaatac tacggtaaaa atatttacat ttaaaggaaa cacatgaaaa catatcaaga 123360
atttatcact gaagcagcta ttaattctca aattattgct gaatctttta ctgatctttt 123420
gaaatttaaa aaaggtcaaa agatcactgc tgtattagat gatggtacag aagttgagat 123480
ggatgtacag ggatataatt atgcagtaga tggaaaactg tataataaat ctcacgctaa 123540
atttgattca tttgacgact ttgttaatac agttgaagat gaaaaaactc gtagatcaat 123600
ttcaactggc gatgctaagg ttcttatggc gcacggtcat gaacgtatcc gcgccaaaca 123660
gaataaaatg ggtgaagata atttcgcatt agttggttat caatctggta aacaaactta 123720
tggttatcag cgtactgcta ccatgtataa caaaaatggt aaaatagctt tcgtgaatag 123780
caaaggttct attcagtacg tcaaatcatt caaataagca aataagaaat atgggaacaa 123840
gctggacctc atgattctat gagggattcc cgccaacctg taataaggtc gagcccaagt 123900
gcggtaatgg gtaaatacag aaatggacaa ttcatgcgcc atggaatggc ccaaatttag 123960
agagaataaa atgagaacat ttttaactgg tccttatcta tccctgatga atgcttttac 124020
acaccattct gatgctagag tagaagaaat ttgcaatagt ggattttatg tacctgattc 124080
gtcgcattta tttaaagaat attgtacact tcgactagat ggtggacgtc aatctggtaa 124140
atcaactgct gtgactaact ttgctgctaa ttggctgtat gacggtggaa cagttattgt 124200
tctttctaat acttcagctt acgctaaaat ttctgcaggc cgcattaaaa aagaattttc 124260
tcgttattct agtgatgata ttcgattccg cttatttact gattctgtcc gtagttttat 124320
cggtaataaa ggaagcaagt tcagaggttt atcgctttcg cgaattttgt atataattga 124380
tgagcctgtt aaatctcctg atatggataa aatttacgat attcatattg aaactgtgca 124440
acactgttgt aatagtaaat gttgcattgg tggtattact cgtccgcagt ttttcgtaat 124500
cggaatgcaa tgatgacaga cacacagctt ttcgaatatc tttatttttc gccaaaaact 124560
attaaaaata aattggtgaa tcattttgaa attttggcaa ataacaacgt cttgagcgaa 124620
ttttatccta agcaatacaa attacaaaaa ggtgtattca aaggatgcag agttttgtgc 124680
actgctccta atgcaagatt aatgaataaa attccatatt ttaccatgga atttattgat 124740
ggacctttta aaggactaat cacccaaagt ttaatggcat atgattctga gccattttta 124800
attaaagaac agtcttggat aaatttattt tctaattgag gttatatgaa agcatatcaa 124860
attcttgaag gcacacataa aggtactatt tattttgaag atggtattca agcacgaatt 124920
attgtttcta aaacctttaa agaggactct tttgtagacc cagaaatttt ctacggtttg 124980
cacgcccgtg aaattgaaat tgaaccacag cctacagtta aaattgaagg tggtcaacac 125040
ctgaacgtta acgttctgcg tcgtgaaact ctggaagatg cagttaagca tccggaaaaa 125100
tacccgcagc tgaccatccg tgtatccggt tatgcagttc gctttaactc tctgactccg 125160
gaacagcagc gcgacgttat cgctcgtacc tttactgaga gcttgtaatg gcaaagataa 125220
ttattgaagg ttctaaagat gtgttaaatg ctttcgccga gtggtttagt aattcaggcg 125280
aacagcaatt taatgaagcg tggaccatgg gtgatattga tggaatttat cctacgacag 125340
aaatttctgt tcaaggatat ggcattcatg aacctattcg tttagttgaa tatgatttat 125400
gtactggtga ggaagtcaaa tatgattgaa gatattaaag gttataagcc acatactgaa 125460
gagaaaatcg gtaaagtgaa tgctatcaaa gatgctgaag ttcgtttagg acttatcttt 125520
gacgctttat atgacgaatt ctgggaagca ctagataatt gtgaagactg tgaattcgcg 125580
aagaattatg ctgaaagcct cgatcagtta actattgcta aaacgaaact caaagaagcc 125640
agtatgtggg cttgtcgtgc tgtgttccaa ccagaggaaa aatattaatg gctcaattaa 125700
gcgcagggtt tggttatgag tattatactg cccctcgtcg tgtatctgtt gctcctaaga 125760
aaattcaaag tcttgatgac ttccaggaag tagtccgtaa agctttccag gactatgcgc 125820
gttatcttaa agaagattca caggactgtc tcgaagaaga tgaaattgct tactatgagc 125880
aacgtcttga acagcttaaa aacctacatg aggttcgtgc agaagttaca aagtctatga 125940
ataaattgat tagatttaaa gaataactgt ttacttttcc tcttgactat ggtataattt 126000
ttctatcagt taagaggaga ataacatgac tatcaacaca gaagttttta tccgtcgaaa 126060
taaactccgt cgtcactttg agtcggagtt tcgtcaaatt aacaatgaga ttcgtgaggc 126120
atcaaaagca gcaggagtct catcgtttca tctaaaatat tctcagcatc ttcttgatcg 126180
tgcaattcag cgggagattg atgagacata tgtttttgaa ttattccaca aaataaaaga 126240
ccatgtttta gaagttaatg aattcctgag tatgcctcca cgccctgaca ttgacgagga 126300
ttttattgat ggggttgaat atcgtcctgg gcgtttagaa atcactgatg gaaatctttg 126360
gcttggattt acagtttgta aacctaatgc gaagttcaaa gacccgtcac ttcagtgcag 126420
gatggcaatt atcaacagtc gtcgtttacc aggaaaggct tctaaagcag taattaaaac 126480
tcaatgaggt aagcatgaga aaagcactac tcgctggtct attggccatt tcaatgatgg 126540
cacatagctc cgagcatact ttcagtaatg tccaactcga taacatgcgt tacgcgtatc 126600
aattcgggga acagttttct aaggatggaa aatataaaac acataaaaat atccacaaga 126660
gcggattagg tcatataatg gctgctattt tatggcaaga aagctctggc ggagttaatt 126720
taaaatctaa accaaagcat cacgcttatg gaatgttcca aaattatttg cctactatgc 126780
gagcaagagt taaggaactt ggttataata tgaccgatgc tgaaataaaa agaatgttga 126840
ataaacaatc caattcagct tcctgggcgt acattgaact ttcttattgg ttaaatatac 126900
ataagggcga tataagaaaa gcaatatcct cttataattc gggatggaat gttaaagcag 126960
gttctaaata tgcttctgaa gtcctagaaa aggctaatta ccttaaaaat aataaacttt 127020
tggaaatagt aaatgactaa aattttggtt ttatgtatag gattaatttc attttctgct 127080
tctgcgtcag cagatacatc atatactgaa attagagaat atgtaaaccg cactgcggca 127140
gattattgtg ggaaaaataa agcatgccaa gctgaatttg cacagaaatt aatatatgca 127200
tataaagacg gagaaagaga taaatcaagc agatacaaaa acgatacatt attaaaacga 127260
tatgctaaaa agtggaatac cttagaatgc tcagttgcgg aggagaaaga taaagccgct 127320
tgtcattcaa tggttgaccg tttggtagat tcttataatc gaggattgag tactagatga 127380
ttgtaaaata tatcaagggc gatattgtcg cccttttcgc tgaaggtaaa aatattgcgc 127440
atggatgcaa ttgttttcac gcgatgaaag ctggagtcgc aggtcaatta actaaagctt 127500
tccctaaaat tctagaagct gataaattac agactgaatg gggtgatgta actaaactcg 127560
gttcttactc agtctatgaa aagtacttta ggactcataa agcttactgc tttaatcttt 127620
atactcaatt tcaaccaggg ccaaattttg agtattccgc tttaatgaat tgtatgttag 127680
aattaaatga gtttggtgaa aataaactga ttaaacctac aatctatatg cctaggattg 127740
gtgcaggcat aggtaaaggg aactgggata ttattgaaga tattttagat acatattcct 127800
ctaaattaga aattgtgatt gttgattggg aaccgttatt atgaatatac attatccaca 127860
tccatatgac ccaaagaata aggcagtaat tattcgtcaa tgggaacgca tttgccgtac 127920
taaatgtcca attaatagtc cacatgatgt agataaagac tacattggaa cattcgttga 127980
atataccttt attgataaga aaggtcgtaa acaacatgta gaagaatact gcttaaaggt 128040
tacatggtta tgagccaaac tagtattctt aaaaatgccc actgtgaaaa gtgtaagtgg 128100
cctgttgttt ttgctttatg taatgatgaa atggcttgtg atttcgatta ttggtgctat 128160
tgttctaata aaggatgcat caatcataaa ggtgaaggat tttattcagg attttatcct 128220
tatcctgatt tcgttaaaga aggtaaacca aaatgaatag ttttgagtta caatatgaag 128280
tgttacgtga gcttgataat ttaattgaac tcgctgtcaa taaaggtttt gccattggaa 128340
tcggtcaaaa agatactgat catttaacta cggaaatatt taagcaaaag cgaattattt 128400
taaaactcct ggaaaatata tgagtctgag taaagaacaa aaagataaat tgtttgagct 128460
tatccatgaa cttctagatg agcatgcaga agcaaacacc ttttatgatg aatacggccc 128520
gctatctccc gaacaacaag aagaatttgc tgaccggttt gataagaaag aaaatgaatt 128580
aatagcttat gtgaatacgc tttaagaagg tgatatggcg agtttaattt ttacttatgc 128640
agcaatgaat gctggaaaat ctgcttctct tttgactgct gcgcataatt ataaagaacg 128700
cggaatgggt gtattagttc ttaaacctgc tattgatact cgcgattctg tctgtgaagt 128760
cgtttctcgc attggaatta aacaggaagc gaatattatt acggatgata tggatatttt 128820
tgagttctat aaatgggctg aagcacaaaa agatattcat tgtgtatttg tagatgaagc 128880
tcagttttta aaaactgaac aggtgcatca attaagccga attgttgata catataatgt 128940
tcctgttatg gcttatggac taaggactga tttcgctgga aaattatttg aaggttctaa 129000
agaacttttg gcgattgcag ataaacttat tgaactaaaa gcagtttgtc attgtggtaa 129060
aaaagcgatt atgacagctc gattaatgga agatggaacg ccagttaaag aaggtaatca 129120
aatctgtatt ggtgatgaaa tttatgtttc tttgtgtaga aaacattgga atgaattaac 129180
taaaaagctc ggttagtgca aaagttataa ataggtttat ctaactaaag gggtatatat 129240
gctacaatta actgaaaagc aacttcgcaa tcttactgtt cttcaattag atgaaattcg 129300
tagggaagtt ggaaatatca tttcagcttt gcgtcgagaa gtatcactca accaatctcc 129360
ggcagactat actagattgc gaaattttga aaaatacctt gataaagtta aggccgtgca 129420
tcggcataaa gtaaatacag gacaaaaatg ataggaggcc tttatggcct taaaagcaac 129480
ggcactattt gccatgctag gattagcgtt tgctttgtct ccaccaattg aagcgaatgt 129540
cgatcctcat tttgataaat ttatggaatc tggtattaga cacgtttata tgctttttga 129600
aaataaaagc gtagaatcat ctgaacagtt ctatagtttt atgcgaacga cttataaaaa 129660
tgacccgtgc tcttccgatt tcgaatgtat agagcgaggc gcggagatgg cacaatcata 129720
cgctagaatt atgaacatta aattggagac tgaatgaaat tcagcgactt ttcacaaagt 129780
ggaaaacctt caaaggcaga tgaatactta ggtttattaa tggctgcaca agcttatttt 129840
cattctgcgc attttgaaac taaaagttat gctagacaca aagcatacga ttttattttc 129900
tctgagttgc cagatttgat tgataaattt ggtgagcaat atttggggta ttctggtaga 129960
aaatacacac cttcaattcc agatgccagt aaacttccta ccgacacaat taaaatgatt 130020
gatcacatac tagaccaatc taacagcatt tataaagaaa tgcctccagc cattcaaagc 130080
acgatagatg atattactgg gatgttttat caaagtaagt atcttctttc cctcgaataa 130140
cattagtctc cttcgggaga cttttttcat tttaccggtt tactttccat ttgagctgtg 130200
atactataca accatcggat aaagaggaga acatcatgaa aattgaagca ctcaatcaag 130260
aaggaaatat ctacgtcatc attaatggtg attttttcgt caacatggat gacgttacta 130320
gtgaagaact tgtagaactt cttaagaaac gttatgatat gtgtgatgaa gctgcaactc 130380
acatggcgtg tgcaatattc tctctttcat atgtggtgga ataatgatta gcattgaaca 130440
agcagataaa attaaagaat tggtagcttt aattcgcaaa gcagatgagg aacttagtga 130500
ctttgcttgg ttttcgtcgg gcattgcaaa taaaggtgct gaagaacttg aagctaaagt 130560
tgataatgct gtagaagcgt tagatatgtt tcttgatgaa attatcgatc ataatacgag 130620
agtttaagta tgctaacacg tgaacagttt gaaaaaatca ttaaattagc acgtgatatt 130680
gaaatagatt cataccaatt ggcagttgag cattgtgaag gatattcata cgatggtata 130740
gaaacagcta aaaaggattt ggataaatct aaagctaagt tagttcaata tcttgaaatg 130800
attaggtgga ataatgaaaa ctgaaaagca gatgttttta atgaagctaa ttgaagaata 130860
tgctaatgca gtttctgact atgaatgttc ttctcgtgaa agaggtacag ctttcgctaa 130920
agaagaattg aaaatcatgg ttgatgctca tacaaagctt cagaatttta tcgaaaacgt 130980
catttaatgg tttacaagtt ggcaaggtta tggtatagta atcttgtcaa ctgccaggga 131040
gaagagaatg aaagttttgt ttgttgtgta tgtgatgatt caatataatt acccgatgtt 131100
tacttataat ctggtgaaca acattattga tattattcaa aggagtatgt aattgtgagt 131160
gagtcgaaga gaatcaatat gaaacgatta gtattagaag ttagtccgct ttttggtgaa 131220
ttggctatag aaaaagtaaa taacatgtat cgtttgacgc aagaagacga tatgctatat 131280
tttacgccta gtgaaatcat tcatttaatc aaaattgaat atccttatac tgataaaata 131340
gtaagcatca atgatgagca caaaattcat ttttattctt catgcctagg atttaatatt 131400
aaaagtgagt caatgtgttt atcagttatc cattgggata gttttatagc taagattaaa 131460
tatttttatt attctaatga aagaaaacat agtttaaaat ggctcaaaaa ttgcaatgct 131520
attattacta actcttacaa tcagaatgat gaaactcttt taaatgtatc aaaatgttat 131580
gaagaaggag atgtcttaac tattcgtcaa attgatgatt ttcgagcaca tattgtcaca 131640
tttaccaaag acgaagctat tgcgctaaag acttatcttg attctgtcat tccaactatg 131700
atttcaaagt gaggaaatat gtttatttca agtggaagtg gtttaattcg tgttgaattt 131760
aaaaatgaca tcttccttag tcaaggagat gatattatta aaatgagtta tgacgaaatc 131820
aagaaaattt gtcatgctct tgaaagccgt ggaaacgtaa atgctgttat tgatattggc 131880
gatttatggg tgacacttta tgaagtatcc gaaggattta acattgaaga tgaaaataac 131940
attttagcta ttgataaaag aactgatttg tttgatgtat taaaagccta tgagcagtca 132000
aatggcggaa gaaaagctgt attgatttat caaaaaccgc attcatgtgg aactgcttca 132060
atcatttcaa atattgaagg cgaagttgat acttatatgt gtgttttaaa agctggtggt 132120
gaccgtcatc cggattttat ttctattcgt caaaacaatg gagaaatttc attatcaaaa 132180
tcagaagctg aagctatgat taagtattta acaaccgtta cgccttcaat gaaaggataa 132240
ttatgattat taatgaaaac tcttggcact ataaattatt caaattgttt aacgatgaat 132300
ggcaacgacc taagacacta tgcgcatatt tttggtctat tgccattcct acatttttcg 132360
tttctatttt tgggtgtgct atactcgtag ggctaacaat tatttgtgca gaaagcctac 132420
aacgttggct tattttcggt agtttatgga ctcttcttcc atcggcattt atacttgcgc 132480
ttttggttgt tttacttatt atcggttcat ttgttattcc tgcacatttg cgtgaaaaat 132540
ataaagatta taaatggaaa aaggattatg ctttacacgt agaaaatatt gatagggcgt 132600
ataaaggttt acctcctatt caacccaaga aatcgattat tgttgaattt ttaaaagctc 132660
gtaaatctaa agtatgtcct gttattgaat ataaggctga atgatgaaaa cagtaatgaa 132720
aagctatttt ggtagtcatc tttatggaac ttctacccca gaatctgatg tagattttaa 132780
agaaatcttt gttcctcctg ctcgcgatat tcttatcgga aatgtcaaag agcacatgag 132840
taaaaacact aacaacacat catctaaaaa cactaaagat gatattgacc atgaactata 132900
cagtcttaaa tatttcttta aattagcagc agatggtgaa actgtagcat tggatatgct 132960
tcacactcca cctgaactag tggttaaatc tgatttgcct gatgtgtgga agtttattca 133020
agacaaccgt tctcgttttt atacgactaa catgaaatcc tatttaggat atgtccgcaa 133080
gcaagcttct aaatacggtg tcaagggttc tcgtttggct gcattacgtg atgtattgaa 133140
agtagttaat caaatccccg agcaatgggt tgattaccaa gaagatggtt ctattaagca 133200
gcgtcgcact aaagttgaag atattaagca tcgtcttcca gaaaacgaat tctgtgaatg 133260
ggtgttccat aatcatgaga aaacaggccc acagacgttt tacacagtgt tgggtcgtaa 133320
atatcagaca actctttctc ttattgagct taagcagtca ctgaacaaat tagatgctga 133380
atatggtgaa cgtgctcgta aggctgaagc caatgaaggc attgactgga aagctctgag 133440
ccatgcttgc cgtggtggac ttcaactatt ggaaatttac aaaactggtg acttgattta 133500
tccacttcaa gatgctccat ttattctcga cgtgaagttg ggtaaacatc catttaaaac 133560
cgttcaagag tttttggaag atgtggtcga tcaagtagaa gcagcatcta ctgaagcttc 133620
taagaacggt atgcagcaaa aagtagacat gagtttctgg gatgacttcc ttgagaaggt 133680
ctatcttgaa aaccatcgaa gttattataa atgataggga gccttcgggc tcccttttta 133740
tttcaaattt ttttttttca caaaactgtt tacaagcata aagctttatg gtactataca 133800
actatcaact actgatacag atttggagaa taaaatgaaa actgtaacta tcaataaggg 133860
tatctacttc ggtaaagaaa tctctggaac ttttgagctc ttaggtgaat ggttcccaga 133920
taatgctccg gtagatgcac aaggagatgg taaagttttt gttgaaattg acggtaagcg 133980
tcgcggtgtt tgggtttaca aatcagacat ttcatatgat ggtgtaaaag ttgaagaagt 134040
taaagaatca tatgaagata tgaaaacccg cattaataaa agatttaatg ttatgggaat 134100
gatgacgaat ggtattatta acggaaacat tcgttcatta attatctctg gtgcggcggg 134160
tattggtaaa acgtattctt tagataaagc tttaaataaa gcaaatgata atggatacat 134220
tgaatataaa agcattaacg gtaaaatctc tggtatcggt ctttatgaac agctctggaa 134280
taatcgtgaa gagaattctg tccttttgat tgatgatgtg gatgttttct ctgatatgga 134340
cattcttaat cttctgaaag ctgctctgga cactggagag acccgtaaag tctgctggag 134400
caccgcatct tcttacttag aagaaaaagg cattgagcgt gagtttgaat ttaaaggaac 134460
gattgttttt atcacaaacg ttgacattga ccgcgaatta gaccgtggta ctaaacttgc 134520
tccacattta caagcattag tgtcccgctc agtttattta gatttgggtg ttcacactaa 134580
tgaagaaatt atggtcaggg ttgaagatgt tattctttca accgacatga tgcaaaagcg 134640
tggtctttct gatgaagaaa cttataaagc attatcatgg atgaaagtta atgttaatcg 134700
tttacgcaat gtttcactgc gtactgctct ttatcttgct gactttatta tgaccgacaa 134760
aaacggttgg caagaaatcg ctgaggttac tcttctgaaa taaattcata agaggccttc 134820
taagacaaaa aggcagttca gaaatagatt atatggactg ccattaaaaa gatgactaga 134880
attaaactgg taaatggagg taatgatgtt atactcaaag gctcgtgaaa tttacgaaac 134940
taagattaaa gaagctgtac ttcaattcgc aacaacgatg cgatggacaa atgattggga 135000
gtattcaaaa aatcataaga agcccatggt gacaagaaag gctcatatgt tagtgttaat 135060
agaccgtgag cagattaaag cccgagaagc cctccagaat cataaaaagg ctgcctttga 135120
atggtttatg gataacactg ctcctgagac taagaaagca gtgagcgcat ggttcagtgg 135180
aaaaaattgt gaaagaagtt tcttttagtg gtttacaaga ccgttcctct gtggtactat 135240
acaactatca actacggagg aacataaaat gaacgctaaa gatattttca acctggtaaa 135300
ttacaacgat ggtaaattta aatctgaagc acaaagcaag ttctttaatg acatctcaat 135360
cggaggtgaa atcacggttg atggaggaca aatttacaaa tcccgttgga attggatcgt 135420
tattatcgat gagatcggta ttgtagaaat ttacaagaat acgaataaaa atcgtacatt 135480
acactggtct cgtgatacta acgaacagta caaaaaggat aaagcatcta aattatctcg 135540
tgtaactcaa gaagatattg agtttatcaa gaaagatatt ttaatgtatg ataacttaat 135600
tgctgaagag caagctgtta ttgataaatt tgatgagatt aaagcttctc gtgaaattcc 135660
tgattttatg aaagaatcag taaatgaacg atacactctc atttcagagc gtattgaaac 135720
ttacaaaaag caaagagctg aacgccagaa cactcttcgg aaatttgaag aacggttaaa 135780
gacggtactc gcataaccgc tttataccaa ggatggtata atggttctaa gcccttttaa 135840
ctgagattat tatgaaacag ttgataatta aaagattgaa tttattgata tgttgtttat 135900
gtgtagtagt tgcatatggt tattacgcaa ttaatgatta tatgcattat aaagattatg 135960
atgttactgt agttaatacc tttacaggaa ctcaaggaaa ggggtctagt ttatcgttta 136020
ttgctgtata tgaactcaaa gacggttata gatttagtga atatatttcc ccagagatgt 136080
attcttcaat agaaaaaggt gataatatta ctgtaagttt acgtcctttc gacgtaaaac 136140
agacattgtt tgataatatt gtttggttct ttggaatggt attagttcaa tctgtgtgtg 136200
gtgcttatat agtctgttct atcttattct gtatatttag taaaattgaa attgagtgag 136260
gaaaatatgt cagtagcaat taataatgtc aatgcagtaa ttaaatcttt agttaataaa 136320
aaatcaaatg aatggactgt acttcaacgc gacgagtcag ataaattttt tcataaattt 136380
aacccagtac taaatttaaa tgttatcgat aaagatgttc acgccgaaat tttagataag 136440
tttaaagttg atattggatt tggattagaa aaacatttac aacgaacaaa cgggtctgga 136500
atgcttttat ctaatcgcat catgaaagcc cttaataaaa ttggagcgtt gtctcgcatt 136560
aacgcgagtg aaattcttcg caattataat aaaggatatg acctttatgg tcgactaatg 136620
ccgaaattat cattcgatca aatgattgcg gatttgtggg aaaatcaacg acgattatta 136680
gcattaggcg ctagattagc taaaggtcta gataaacaaa tgatttttaa gaccaataat 136740
acagaagacc ttaaatgctt taaatttagt atgcgtggag atgattatta catcagagct 136800
cactctacag attatgttaa tatggggcat catctctgtt tagcttttga aattttaaaa 136860
gaagctggaa cattagaata tgtgtctggt gctaaatgtc cgattggttc aagttgtatt 136920
ttaatttatc gcccggatga atccagttca actaaattgc ctacaaaacc tgtaccagtt 136980
cgtagtaacg aaaaacattc tgaacaaatt gattatttta ataagcaaat tgaagagctg 137040
aatatttcta ttcaacaata tgacgatgaa attttcagac tatctggatt gagtagtaaa 137100
gctaaatctg aacgtgaaaa attaattaaa attgttgatt tacttaaatc ttaaggaaca 137160
ccatgaaaac tcgttctcaa attgaagata tggttcgtaa tgccagctat acccgtgatg 137220
ttatgacatt tttgtgtgaa aataatttag accctgataa agttaatcgt gttattcatc 137280
actttaagta tacgaatagc agtgaatggg tgcgtaattt tagcgaagca gggtatatta 137340
cgcaaatgac ggctcgtgag cagctcaccg atttctgtaa aactattgat tataaaaatc 137400
ctctatttgt tcaaggcgtt ggtcaaagta aggtcgattt atcatctgga ttttttaatc 137460
caaatcatta tcgtattgaa tggagattta ttgctctgtt ccgtagacaa ttaaagcaaa 137520
ttttatcaac tgcgagtcga ttaaaaggtt ctgatattaa cttaaagaat ctgaaatttg 137580
atggttatac tcttcagatg gaagtaagac cattaaaaga aaataataga actgcacgaa 137640
ttagctttaa acctaataca aaaaattctc tttcaatttg cgaatgcctt aaatcacagt 137700
taacagaagc atttaagtat atggatgttg ttgccgctgt tcagtctaag attttacctc 137760
attttgagcg aaattgggaa catacaacaa cgtatgaact tgatatgatc gtttcattta 137820
aatacgattt tttgagaaag gacgaagtca cgcaagagaa aaagcaagaa gcgcaagata 137880
acttaaattt aaatttatcc aattactcat caaacgatcc taaattttgg atgtatagtt 137940
caggtaataa ggatgcatgg aaatttaata aagtgaattt tcttcctatt gaaaatccga 138000
gtcttaaacc tgttgaaaaa tggcatgcag atgcgattga gaagtctatc aaggcagtag 138060
atgatgaact cgttaaagca actaatgaag tgctagaagc tgaaaagacg ctagaaaaag 138120
ctcaagaaaa agtcaaaaat ctcacgaagc aacgttctaa actgaacaat gcactaaatg 138180
cactgaacta gtttacttta ccacaaggat gtggtataat gttcttactt tctactgagg 138240
agattaatat gactcgtaac gaatatatca aatcattcaa tagtgttatt gatgataaag 138300
ttaaacttat gtctagtcag aatagcgtta tttccattat caatcaatgg ctcaataata 138360
ttgatgtaag cattgtttct tcaagcaaat ttattcatga agttcataaa atttctagtc 138420
gtacagataa agatgacatt aaggaaacct ttaaaggttc tcgtcttctt tcatacttag 138480
tcaacagaga tattcttagt aaatttggga aagaaattaa acgaactaaa gatgtagtag 138540
gatataattg gttcggtgat gttaattctt atcatcttaa tattaaagaa gaccctgaga 138600
atatttttac tcgtcgttgg gttagtaatt tcagactttt caagaagcaa cttctaaaat 138660
ccgcttctaa attatgctat ggcgattatc gtcaaattca tccttgggct tctgatatga 138720
ttatcataaa agaatatgaa cttgataaaa ataaagcagc tatttttgtg aattatgaat 138780
tttttacacc agaagctaat caaaagaaca ttaataaatt tttctcaatt gccagtgata 138840
taactcgtca attagagact gcattacttt gtatggaaac ggtagaaaat attcatacat 138900
atcctttcaa aaatttatgc ggttgggaag gatataaaat tgtagttagt ctccgtgaag 138960
taaagtgtgc gtactcaccg actgataaag aaatttacca acaaaaatgt gatgaaattg 139020
tgaatactcc taaagaagaa actacccttg aggaactaat ggataatctt gatgattcac 139080
ctgaaccggt agaaattcgt tcagaagtta ttgcattaga aaaagcttat aaggaagttc 139140
tagaaatttc taataaagcg cagaaagaat atgagcaggc taaaaagatt tgggaagaat 139200
ctgttaatcg tcttgatcgt cttgaacaag ctttacagtt aattaagtaa aatttaaagc 139260
caaggatggc tcggagtata aattattaac taagtgagaa gaacatgaaa actcgtaaac 139320
attatattga ttattttgac agtcttatta ctaaacatcg taattatcag atcgggcaca 139380
gagcagtaat caataatatt cttcgtgatt tccttcaata tgttggccag gaaaatcata 139440
tctgtaaaga tactcaaaac gcttattctc attcgttagg caatttgctt gaatggttta 139500
aacgttctcg tctgttatct tctactgtag ctagtgataa cattaaaaac tttatgaagc 139560
cgagcttcat taaatctgcg acatctataa ctgatttggt tgaatttact attgttaacg 139620
atgttaaaaa gacccacttg gctgattggt tatctaccat tcctgaaact aaatttgctg 139680
ataaatttgc ttgtcaattt aatgaccaag tgaatatgct ttttaagcat gctcgcaaac 139740
tgtttaccgc gggtgatgac cgtacaaata cagttcatgt taaggactgg gttattgctg 139800
atgaagtaac acacaagcca ggtggttcat cagtattaat taatatccag gttccttatt 139860
attactcacg taatctcggc accatgacag ctagagaaat taataagcac aacaaaacta 139920
ttcgttcgtt gtcttataaa ctctgcacga tggtggagat gatggacgta gtggaaatgt 139980
atgacgaaac cgaagataat ggttcaatgt tatacagctc acgcattcta attaaactga 140040
agaaccctaa tacatacaag ccagttgtaa aagaacccaa agtagaaaag gttgataacc 140100
tgagtgaaga acgcgaatat cttaatgccc gcttaattga agttgaaaaa cagattgaag 140160
agcatactaa agttcttaaa gatttaactg ccaaagcaaa tggtttacgt aatgctattg 140220
aggtattaaa atgaaaaagc gtctattaga agacattgca gcttcaagta attctagcct 140280
aattaaaatt attatggctg gtgaagaaga cgatctggaa atgcgtggaa agattcatgg 140340
ctgtgacgat ttagatttta aacctccagc ttgggatgcc attatggcta tggttgaacg 140400
gcgtgaaagg gcttctaaaa acgttcctaa ttgtcctgaa tgtggtactg aacaggtgca 140460
attggtccat tggcagacta ataatcttcg ttataaatgt cgtcattgta aacaccgatt 140520
taaccgagaa gaaaatgaca aagcgtaaag aatatatgga gactgctgaa aaggcagtcc 140580
gtgaattagc aatagcttat tataatgaac atggtaaatt tcctgataga tatagtgtgc 140640
ttaaatctgc tttaactcgt tcatataaaa atatgctatc agaagtaagt gatattatat 140700
acaaacataa agaacaaacg ggccaaagtc ttgattacga cgagactttt aaacaagtac 140760
taggaattaa ggaataatat gtttaaagta tatggttatg atagcaacat ccataaatgc 140820
gtgtattgtg ataatgtaaa acgtcttttg accgtgaaga aacagccatt tgaatttatc 140880
aacattatgc cggaaaaagg tgtttttgat gatgagaaaa ttgctgagct tctgactaaa 140940
ctaggtcgtg atactcaaat cggcttgaca atgcctcagg tatttgctcc tgatggaagt 141000
catattggcg gctttgacca attgcgggaa tactttaaat gatgctcgaa ggaactgatt 141060
atatccatga ctaccgcgga agcgcggtat atgtaggtga tgaagttgca gtttactatg 141120
gatatggaac tttgatgaca gccaaagtta ttcaaattaa aaataaccgt gctaaacttg 141180
aagtttatta ttctaatggc gaaaagtcta tttctaagtg gaaatacggc gattgtatgg 141240
tcaaactggg gtaaatatga tttacgatat tagtgtagca agaactccat caatggttac 141300
tattccagct gaagaattag atcgtcttca taaaattgaa gaacttcttt gggaaattga 141360
atctgatttg ccatcaggac tagaatcctg gattgattat gaagaactta ataagcttcg 141420
gagttaaacc ctggtgggcg gttagatggg aaactgtaga gccagagccg gaagaaccgg 141480
tttacactga tgaagaaaca gtatataatg aacctacaat aaatgactta attgatatgg 141540
agatgggaca tgattacagt agataagtgg tttagaatta atcgtgctga tatagggctg 141600
tgtaattact ggccggaact tagtgcaggt actgtcttta aagttcgtga acttgcaaaa 141660
gaatgtgaag atgatataga acctgatact ggaattattg aaattgaact ttctgatgga 141720
aagattatta acatctacga taagccaatt acgtattggt gcttgtggaa tactgaatca 141780
gtcgcaactg gcgaaattga agaagtcgta gaacgagttg atcaagctat tcataaacct 141840
aaagccgctt ttcaaggtga acgtatttca tacgcattag ctaaattagc tgcacaagaa 141900
aataacgatg gttatgaagg aaatttgatg caagctgcgg cagaatatat tgaatggctt 141960
gaaactcaaa tttctttttc tgaccaaaag attcggcaat ataagcgatt gaatcaaatg 142020
ttttacaata cttgaaaata ataaataccc ttatctattt aaggtaaggg tttattatgt 142080
tattgactgg caaattatat aaagaagaaa aacagaaatt ttatgatgca caaaatggta 142140
aatgcttaat ttgccaacga gaactaaatc ctgacgttca agctaatcac ctcgaccatg 142200
accatgaatt aaatggacca aaagcaggaa aggtacgtgg attgctttgt aatctatgca 142260
atgccgcaga aggtcaaatg aagcacaaat ttaatcgttc tggcttaaag ggacaaggtg 142320
ttgattatct tgaatggtta gaaaatttac ttacttattt aaaatccgat tacacccaaa 142380
ataatattca ccctaacttc gttggagata aatcaaagga attttctcgt ttaggaaaag 142440
aggaaatgat ggccgagatg cttcaaagag gatttgaata taatgaatct gacaccaaaa 142500
cacaattaat agcttcattc aagaagcagc ttagaaagag tttaaaatga caattgaaaa 142560
agaaattgaa ggattgattc ataaaactaa taaagacctt ttaaacgaga atgctaataa 142620
agattctcgt gtttttccaa ctcaacggga ccttatggct ggtattgtgt ctaaacacat 142680
tgccaaaaat atggtcccgt cttttattat gaaagctcat gaaagcggaa ttatccattt 142740
ccatgatatt gattattccc ctgctcttcc atttactaat tgttgtttag tagatttaaa 142800
aggaatgctt gagaacggat ttaagcttgg taatgcacag attgaaactc ctaaatcaat 142860
tggcgttgct actgcaatta tggcacaaat tactgcgcaa gttgcttccc atcaatatgg 142920
cggaacgact tttgctaatg tagataaagt actttctcct tatgttaaac gcacctatgc 142980
aaaacatatt gaagatgcag aaaaatggca aatcgccgat gcgttgaatt atgctcaatc 143040
taaaacagaa aaagacgtat acgatgcatt tcaagcttat gaatatgaag taaatactct 143100
ctttagttca aacgggcaaa cgccttttgt aacaattaca tttggtacgg gaactgactg 143160
gactgaacga atgattcaga aagcaattct gaaaaatcgc attaaaggtc ttggccgcga 143220
tgggataact cctattttcc ctaagcttgt tatgttcgtt gaagaaggtg ttaatcttta 143280
taaagacgat ccgaactatg atattaaaca gcttgctcta gagtgtgcaa gcaaaagaat 143340
gtatcctgac atcatttcgg ctaagaacaa taaagctatc accggttcat ctattcctgt 143400
ttctccaatg ggttgtcgta gtttcttgag tgtatggaaa gattcgactg gtaatgaaat 143460
tcttgatgga cgcaataatc ttggcgttgt aacactgaat cttcctcgta ttgcgttaga 143520
ttcttatatt ggaacacagt tcaatgaaca gaaatttgcc gaattgttca atgaacgaat 143580
ggatttgtgt tttgaagctt tgatgtgtag aattagttcc ttaaaaggag ttaaagcgac 143640
tgttgctcct attctttacc aagaaggtgc attcggggtt cgtcttaaac ctgatgatga 143700
cataattgag ttatttaaaa atggtagaag ttcagtgtcc ctaggataca tcggtattca 143760
cgaattgaat attcttgtcg gtcgtgatat tggacaggaa attttaacta aaatgaatgc 143820
acatcttaag cagtggactg aaagaaccgg ttttgctttt agcttgtatt ctacacctgc 143880
tgaaaacctg tgttatcgct tctgtaaact cgataccgaa aaatatggaa gtgtaaagga 143940
tgttactgat aaaggctggt acactaacag tttccacgtt tcagtagaag aaaatattac 144000
tccgtttgaa aagatttctc gcgaagcacc atatcatttc attgcgacag gtggtcacat 144060
ttcttatgtt gaacttcctg atatgaaaaa taacctaaaa ggtcttgagg ctgtatggga 144120
ttatgccgcg caacatttag attattttgg cgttaacatg ccagtagata aatgttttac 144180
gtgtggaagt acccatgaaa tgactcctac tgaaaacgga tttgtttgtt ctatttgtgg 144240
agaaactgat cctaaaaaga tgaacaccat aagaagaaca tgcggatatc ttggaactcc 144300
tagcgttgtt ccatggaatt taggtaaaat gaaagaaatg gtaaaacgag taaaacatgc 144360
ataggtatta tataatttat aaaataacaa atataattaa ttcaaaggaa tatatcggtg 144420
cgcatagcac cgataacata aatgacggtt atatggggtc aggaacattg attcgtgccg 144480
ctttattaaa atatggtaga aaaaatttta ataaagaaat tttacatgtt tttgataatg 144540
aaaaacaaat gtatgataaa gaagctgaac ttgtaaccga agagtattgt ctaaaagaaa 144600
atacatataa tattaaaccc ggtggaaaag gtggaactgc ctatgaacag acacttgaac 144660
atcgccgcaa aaatagttta gcaaataaag gtaaaaagag aacagaagaa actaaaatag 144720
ctatttcacg tgctttaaag aaatataaac gtacgccaga gcatcaagca aatttaaata 144780
aagccgtaag catagctatg aagcgaaaag atgttagaag taaattagct ggagggcggt 144840
ctgagaaaga taaattatct atatcaaacg gtgttaaaaa atattacaat tctttgagtg 144900
aagaagaacg cgaacttcat cgcaagcgaa ttattgaagg taaaaagaat tctcccatgt 144960
cattggaatc tagacaaaag ctttcaaaag ctttaaaagg acttcaagtt ggttcaaaaa 145020
atccaatgta tggaaaaatt tctccaacta gcaaaaccgt ttcagttgac ggtattaaat 145080
atgattcaat taaaaagtgc tcaaatgcca taaaagtttc tagacatctt atactaaaac 145140
gctgtaattc tactgatgaa gcttggaaaa attggatatt attatgaatt atgacagaat 145200
atacccgtgc tgctttgtga atggccctgg atgcagggtc gttcttttcg ttacaggttg 145260
tttgcataaa tgcgaagggt gttataataa atcaacatgg aatgctagaa atggtattcc 145320
attcactggt gaaacattag aacaattaat tgaatgtttg aataatgatt atatagaagg 145380
attaactata accgggggtg accctcttta tcctgataac agagacatga ttcactctgt 145440
ggttcaaact attaaaaatc tttatcccaa taaaagcatt tggttgtgga caggatataa 145500
gtttgaagat attaaacaac tagaaatgct taaatatgtt gatgttatta ttgatgggaa 145560
gtatgagaaa aatcttccga ccaaaaagct gtggcgagga tcagataatc agcgactttg 145620
gtcaaatacc gatggggtgt ggaaacatga ttaaattgaa ttacattatg gatactataa 145680
atgatatgat ttttcatttt ggtccagaat tttattcgca gtatagttta gtacttatca 145740
atgcttggtt aattaattaa ggataaaata tgtataaatt tcgtaaaggt ttagctgatt 145800
ttcttacaac tgtagcattc tttctgttta tggcagttgg agctattttc cttattcctt 145860
ttattgctat atttttcgtg attagtttaa tttctccaga aaaaggctta tcttccagtg 145920
agttcagtga gcgtctggat aaaattacta acaagctgaa tgctgctctt agtaaggaat 145980
agttgtgaaa caaaataaga ttgaagtcta tggaattcca gatgaagtag gtcgttgtcc 146040
tggatgtcaa tcagttacaa aacttctaaa ggagctcaat gctcctttta ctttctataa 146100
agttcttaca aataatggta agattgagta tgatcgtcca ctgattgtat ctcttgccaa 146160
acgcgccgga ttcacatctc ttaacattcg ttatccagtc attttcatta atgattccag 146220
acaaaagaac attaaacact tcaaagaaac cctcatttca cttggatatg atagagatat 146280
catagaagac taagataggc cctctgggcc tttctttctt acattctgta tattaccatt 146340
ctaagctatc gttcctttct tatcattccc taaaatattt tcacaaagtt gtttacaaca 146400
agttcaaacc gtggtattat taacacatga attgcctttg aggaattgat atggttatga 146460
ttgataaaga aattaaaaag ggacagtatt atcttattaa tggtaatgtt gttcgcgtta 146520
cttacgtaaa tggttatgat gtttattatc ttatacttaa gttacataaa cacatgattt 146580
gtgaccgtgc tgtatttagt tcagttgcta aggaaattaa actccatggg taaaacgtat 146640
cgtcgtaaag acttaaaagt gcgtgattat gactatttcg gaaagcgtaa agctcctgat 146700
ggggtaagtc ataaagatat ggttgaaaac atttttcgct cagataaatg gcgtagaatg 146760
aaaggtattg attcagaagt taaagatgag ttaaatcgtc aattacgcgg tgaagtaaga 146820
aagttgaaaa aatcagttta cattgacgat gattttgatt ataatacttc tcaacgagtt 146880
gctaaacgta aatcaaacga atgttatcgt tacagctgag gaaaatatga atatcaaacg 146940
aatgcttttt aagcaggggt tatacacttt aaatgttact ccaaaaggtg atacaactaa 147000
gtggtcagta aatgactgga ttaaatttat tgatgaaaac ggtaactgga aaatttaaat 147060
gaatcctgaa tctaaattat cacaacgaat tgccgaatct cgtcgtcagt tctttgaaaa 147120
tatgatagcc caaggtattg atgatgaagt ttttctaaat tggttctgga ataataagta 147180
tgcagcatgt gaaggagctt tgtcattgtc agtcgcaatg atgtacgaag gctggaaggg 147240
tgccaaaaag tttagctaag ggcttcggcc ctttttggat aataaaattt taacgtaatt 147300
gaggataatg tatgactatt caaattaaaa acgtcattaa ttcttacgca tatgataaag 147360
tagtttcttt gctagaaaaa ggcgatattg taactcctca aattttggat aaatgggaaa 147420
aagagcttca tcagatgatg aaacagaatg atcagaagat tggacgcaat actgtccgtg 147480
aattgttggt tcaatatatc ttgtcagaat ttgatgttaa agcttttggt gtagaatcta 147540
aagcttatca aaagcatgaa atttccgata aaactattcg tcgcatgaaa aatcaacgca 147600
agaaaaaatt tgcagacctg aaaattacta aggtataatt atgaacgaag ctcttattaa 147660
cgatttgcgt cttgctggat atgaagtaaa tacaaatggc attggtttaa ctcaaattga 147720
aggaaacgga ttcatccttg agtatgaatt tagccaatgg tggttatatg ctaattacgg 147780
cgaattgatt gaatatgttg accaatttga ttcactagat gcagctcttg aagcggctaa 147840
gttgatgaat gtatgaaatt tattaatatt tctattacta ttgaaaatta tggcattttc 147900
tatgttgacc aatgcatgaa aatttcattt ttcccaaata agactggtgt tggatattgg 147960
gaaagtcatg tttctgaatt aaatgaaagt gaatatgtta gcacacatga aaagttttta 148020
gactttttat attgcgctga tattaatgat cattacatag atattcatga atttaaaaag 148080
atgatggaga aagtgttcca agcatactgc ttacttagat aactgatatc ctctatgctt 148140
taagatagat cttcaaatat tatgatataa tagatctatg aattgagcta agaggtgaaa 148200
atgtcagaaa ctaagcctaa atataattac gtaaacaata aagagctttt acaagctatt 148260
attgattgga aaacagaatt agcaaataat aaagacccaa ataaagtagt tcgccagaat 148320
gatactatcg gattagccat tatgcttatt gcagaaggct tatctaaacg tttcaacttt 148380
tcaggataca cccaatcctg gaaacaagaa atgattgcag acggtataga agcttctatt 148440
aaagggcttc acaattttga tgaaacgaaa tataaaaacc cacatgcata tataactcaa 148500
gcttgtttta atgcattcgt ccaacgtatt aaaaaagaac gtaaggaagt tgcaaagaaa 148560
tacagttact tcgttcacaa tgtctatgac agtcgtgacg acgatatggt tgcgttagta 148620
gatgaaactt ttattcaaga catctacgat aaaatgacgc attacgaaga atcaacctat 148680
agaacaccgg gggctgaaaa gaaaagtgtt gtagacgatt ctcctagttt ggatttttta 148740
tatgaggcta acgattaacc tctccggatt cttggaagaa atacctgaag ttgaagctat 148800
tccctattta cttaaaatgt atctcaggga agttttagct cttgacattg atattgatcc 148860
agaaaatccg tatgataccg cttttaaatc taatggtgta gaattaaact atcggtatca 148920
tttaacagat gatgattttt attttatatt agagaaataa tatgactgat aaacccgaaa 148980
ttaatgatga agtggaaaag cttatttctt ctattgaaga aaagaaccgt cttgaagcag 149040
aaagaaaagc aaataagtta ttgtctaaaa acaaacgcga actgaatcgt ctttataagc 149100
atgctcagat tgcggctgaa aataataatt ttgctcaata cgaatatgct atcaagaaaa 149160
gtcgggatat tctaaaacag ccatataacg atgaactcat cagtattctt tggaagacta 149220
ctagatcaca gattgaggat atgattgatg cttacacacg taaaattcaa gcgtcttaaa 149280
attaatgcag gatttactga atctttgaat ggtcatcttt gcgtgaaaat ttctgaaaaa 149340
gaataccatg atagttcaat taaagaagtt aatcctccta ttgtaagagc agaccctaat 149400
atgaaagtgt gggttgattc ctatcaagtc aaaaaatggt ggcaactgtg aaagatgaac 149460
gcccagactt gtgaaataga ttataataaa attcgttcct ctaaagtaga aatgatgagg 149520
cgctttaaag agtctcatga taaagctaaa gcagaaggaa ctataacaca taaacgtata 149580
aaatttagaa gctctaatga gcctctgtat ggtgtattat gcggatagga gcttcggctc 149640
ctatattgct ttataaattt ttggtaaaat aaaccaaaac aatgaggata ttaaatgaaa 149700
gtatgcattt ttatggctcg aggtcttgaa ggttgtggcg taactaaatt ttctcttgag 149760
caacgtgatt ggtttattaa aaatggtcat gaagtaactt tggtttatgc taaagataaa 149820
tcatttactc gtaattgcgc gcatgattat aagtcatttt caattccagt tttattggca 149880
aaagaatacg ataaaacact taagctggta aatgattgcg atattctaat tatcaattca 149940
gttcctgcta cttcagtaga agaagacact attaataact ataaaaaaat tattgataac 150000
attaaacctt cagttcgtgt tgtagtttat caacatgacc attcttctct ttctttgcgc 150060
cgaaatttgg gattagaaga aactgttcgt cgagctgatg ttatttttag tcattctgat 150120
aatggcgatt ttaataaagt tctgatgaaa gaatggtatc cagaaactgt ttcactgttt 150180
gatgatattg aagaagcacc gaccgtatac aactttcagc ctcctatgga tattgcgaaa 150240
gttcgatcaa cctactggaa agatgtttct gaaattaaca tgaatgtcaa ccgttggatt 150300
ggtcgtacga ctacatggaa aggtttttat cagatgtttg attttcacga aaaacatctt 150360
aaacctgctg ggctaagtac tattatggaa ggtctggaac gttctcctgc gttcattcct 150420
attaaagaaa aaggaattcc atacgagtat tatcgtcttc atcaagtaga ccaaattaaa 150480
attgctccta atttgccaac gcaaattctt gaccgttatg taaatagcga aatgcttgaa 150540
cgcatgagta aatccggatt tggttatcag ttgagtaagt tggacaaaaa atatctacaa 150600
cgttctttag aatatactca tctcgagctt ggcgcgtgcg gaacaattcc agtattttgg 150660
aaatctactg gtgaaaattt aaaattccgt gttgataata ctccgctaat ttcacacgat 150720
agcggtatcg tttggtttga tgaaaatgac atggaatcaa catttgagcg tattaaagaa 150780
ctgtcatctg accgagctct ttatgaccgt gaacgcgaaa aagcttatga atttttgtat 150840
cagcatcaag attcaagctt ctgctttaaa gaacagtttg acattattac aaaataaagg 150900
gcttcggccc tttagcttta tacggagttt gatataatga tatttcttgg atatgtgata 150960
ctttttctcg cattttatct attcactaga gcatgttgga ttgggttctt tagcacacca 151020
gatgggttta tttcaataat tttattttgc atttcaatga cggttcttga tatatgaaaa 151080
ttttaaattt aggtgattgg catttaggcg ttaaagccga tgatgagtgg attcaatcca 151140
ttcagttgga tggaattaaa caagcaatag aatattctaa gaaaaatgga attactacat 151200
ggattcaata cggcgatatt tttgatgtgc gaaaagcaat cacgcataaa actatggagt 151260
tcgctcgtga aatagttcaa atgcttgatg atgctggtat tacactgcat actgttgtag 151320
gaaaccatga tatgcacttt aaaaatactt taactccaaa tgcttctact gagcttttgg 151380
ctaaatatcc taatgttaaa gtatatgata agcctactac agtagatttt gacggatgtt 151440
tgattgattt aattccttgg atgtgcgaag aaaatactgg tgaaattctt gagcatatca 151500
aaacttcatc tgcttctttt tgtgttggtc actgggaact gaatggattt tatttttata 151560
aaggaatgaa atctcatggt cttgaacctg atttccttaa gacttataaa gaagtgtggt 151620
ctggtcactt ccatactatc tctgaggctg ctaacgtcag atatattggg acaccatgga 151680
cactaactgc aggtgacgag aatgaccctc gtgggttctg gatgtttgat acagaaacag 151740
aacgaatgga atttattcca aacaacacta cctggcatcg tcgaattcaa tatccattta 151800
agggaaaaat tgactataaa gattttacaa atctatcagt acgtgttata gtaactgaag 151860
tagacaaaaa tctaacgaag ttcgaatctg aactagaaaa agttgtgcat tcattacgag 151920
ttgtgtcaaa gattgataac tctgtcgagt cagatgatag tgaagaagtt gaagttcaat 151980
ctcttcagac attgatggaa gaatacatta atgcaattcc agacatcact gattctgatc 152040
gcgaagcact tattcaatat gcaaatcagt tatatgtaga ggcaacacaa tgatttttga 152100
tgaatttaaa aatgttatga tgagtcagca ttttgaatgc gaagtaaaag atgatattgg 152160
gcataaagaa attattgaat attggtttga accgctagag gttgaagata attgtattaa 152220
aaaggttacg gtctgcactg actgggctgt atcttttaac ttcaacattt tagataatga 152280
cacacctaaa tcattacaag atatggctgt atcttgtatt aaggatgcat actgtgaagt 152340
tttcgacatt tgacattaac gatgaattcg tagcaaatat tgattacacc gaagaagatt 152400
ctagatatgt tggaataatt tatatcacat caaaagcagc acaaggtgtt gtttgcatgg 152460
ctgaatttga tgaatacttt ttagattatg atgatatgat agaatggtct aaaagataca 152520
ttaaaaggaa tcttttgtga agaattttaa actaaaccga gttaggtatc aaaatataat 152580
gtcagtaggt ggaaatccta ttgacattca actagataag gttcaaaaaa ctcttattac 152640
tggacgaaat ggcggtggta agtctactat gttagaagcc atcacatttg ggctttttgg 152700
caagccattc cgtgatgtaa agaaaggcca attaataaac agcacaaata agaaagaact 152760
tttagttgaa ctgtggatgg aatatgatga gaaaaagtac tatatcaaaa gaggacaaaa 152820
accgaatgtt ttcgaaatca ccgttaacgg tacacgtctt aatgaatctg ccagcagtaa 152880
agatttccaa gcagaatttg aacagcttat cggaatgtca tatgccagtt tcaagcagat 152940
tgttgtcctt ggtacagcag ggtatacccc tttcatgggt ttgtcgaccc ctgcgcgaag 153000
aaagcttgtg gaagacctgc ttgaggtagg aacattagct gaaatggata agcttaataa 153060
agcactaata cgtgaattaa actcacaaaa ccaagtgctt gatgttaaaa aagatagtat 153120
tatccaacaa attaaaatat ataacgataa tgttgaacgc cagaaaaaat tgtctggtga 153180
caatcttact cgtctgcaga atatgtatga cgatttggca aaagaagcta gaacgctaaa 153240
atcggaaata gaagaagcta atgaaagatt agttaatatt gttttagatg aagacccgac 153300
tgatgcattt aataaaatcg gtcaagaagc agttttgatt aaatcaaaaa ttgactcgta 153360
taataaagtc attaatatgt atcacgaagg tggattatgt ccaacctgtt tgtcacaatt 153420
aagttccggt gataaagttg tttctaaaat taaagataaa gtttctgaat gtacgcattc 153480
gtttgaacag ctttcaacac accgtgataa tttaaaagtt cttgttgatg aataccgaga 153540
taatattaaa acccaacagt cgttggcaaa tgatattcgc aataaaaagc aatctctgat 153600
cgcagcagta gataaagcta aaaaggttaa agcggctata gaaaaagcat cttctgagtt 153660
tattgaccat gctgatgaaa tagcactgct tcaagaagaa cttgataaaa ttgttaagac 153720
aaaaactaat ttagtaatgg aaaaatacca ccgaggaatt ttgactgata tgctcaaaga 153780
ttctggtatt aaaggtgcta ttattaaaaa gtacattcca ttatttaata agcagattaa 153840
ccattatctt aaaataatgg aagcggatta tgtgtttaca ttagatgaag aatttaatga 153900
gacaattaaa tcccgtggtc gtgaagattt tagttatgct tcatttagtg aaggtgaaaa 153960
ggcacgaatc gatattgctc ttttatttac ttggcgtgat attgcttcta tcgtatctgg 154020
tgttagtatt agtacattaa ttcttgatga agtgtttgat gggtcatttg atgccgaagg 154080
tattaaaggt gtagctaata ttataaattc aatgaaaaac actaatgttt ttataatttc 154140
gcataaagac catgacccgc aagaatatgg tcagcatctt caaatgaaga aagtcggtcg 154200
atttactgta atggtttaat ttataagaga ttatgcttta atttattaga gtataatctc 154260
tatggaggaa aaacatggaa tattcaactg gacagcatct attaactttt cctgaaataa 154320
aacgatatat tctgagaaat aatttttcta atgaagagca tatagttact gaatctatgc 154380
ttaggaatgc atttaaatca gaatatacaa aaataatgtc caatagaaat gaagcttgga 154440
ctgttactga ttattatgac taaaggtgta ttatgactaa aattactgtg aattatactg 154500
ttgatgtaaa agatattcag ccaaaacacg tgcgttctga atcaaatcca caaaaccaaa 154560
ataaaattcg tcgagcatgg gttttgtctc tttctgataa cgcaatggaa gttattcaga 154620
acaaaattaa atctgcacct gctcgtcatg cgtattatga agctatcgat cgtgaagtaa 154680
gtaataaatg gattgaatta atgcgcaaac atactacaga atctctaaac gccggtgcta 154740
aatttattat gacttcatgt ggtgaacgcc ttgaagatga atattgtggc aatgcagatg 154800
aacgtctgat tgttgccgct caaattgttg ccgaaacaat cgcagctgat tttaatcgtt 154860
aattgcttta ttaaattagt tataaaatta aatctcattt gaattgaagg aaattacatg 154920
aaactgtcta aagatactac tgctctgctt aaaaatttcg ctactattaa ctctggtatt 154980
atgcttaaat ccggtcaatt tattatgact cgcgcagtta atggtacaac ttatgcggaa 155040
gcaaatattt ctgacgttat tgattttgat gtagcaattt acgatttgaa cggttttctc 155100
ggtattctgt ctttagttaa tgatgatgca gaaatttccc agtcagaaga tggtaatatt 155160
aaaattgctg atgctcgctc aacaattttt tggccagcag ccgatccgag tacagtagtt 155220
gctcctaata aaccaattcc attcccggta gcatctgttg ttactgaaat taaagctgaa 155280
gaccttcaac aactgttgcg tgtatctcgt ggtctgcaaa ttgatacaat tgctatcacg 155340
gtaaaagaag gtaaaatcgt aattaacggt tttaataaag tagaagattc tgctctgacc 155400
cgtgttaaat attctttgac tcttggtgat tatgatggtg aaaatacatt taatttcatt 155460
atcaatatgg caaatatgaa aatgcaacca ggaaattata aacttctgct ctgggcaaaa 155520
ggtaaacaag gcgctgctaa atttgaaggt gaacacgcga attatgtagt agctcttgaa 155580
gctgattcta cccacgattt ttaatagagg gcttcggccc tttataattt acactaaaac 155640
ttgaatgagg aaattatgat tactgtaaat gaaaaagaac acattcttga acagaaatat 155700
cgtccatcta ctatcgatga atgtattctt cccgcctttg ataaagaaac ctttaaatct 155760
attacaagta aaggtaagat tccacatatt attcttcatt ctccttctcc aggaacaggt 155820
aaaacaactg tagcaaaagc attgtgtcat gatgtaaatg ctgatatgat gtttgtgaat 155880
ggatcagatt gtaaaattga tttcgttcgc ggtcctttga ctaattttgc cagtgcagct 155940
tcatttgatg gtcgtcaaaa agtaatcgtt attgatgaat ttgaccgttc aggtttagca 156000
gaatctcagc gacatcttcg ttcctttatg gaagcttata gttcaaactg tagtattatt 156060
attactgcta ataatattga tggtattatt aaaccacttc agtcacgctg ccgagttatt 156120
acattcggtc aaccgaccga tgaagataaa attgaaatga tgaagcagat gattcgtcga 156180
ttgactgaaa tctgcaaaca tgaaggaatt gctatagctg atatgaaagt tgtagcagct 156240
ttggttaaaa agaattttcc tgattttcgt aaaactattg gcgagctcga tagttattca 156300
tctaaaggtg ttttggatgc tggtatttta tcactggtta ctaacgatcg tggtgctatt 156360
gatgatgttc ttgagtctct caaaaataaa gatgttaaac agctcagagc tttagcacca 156420
aaatatgcag ctgattattc gtggttcgta ggtaaacttg ccgaagaaat ctatacacgc 156480
gtaactccgc aaagtattat tcgtatgtat gaaattgtcg gcgaaaataa ccagtatcat 156540
ggaattgcgg ctaatactga attacattta gcgtatcttt tcattcaatt ggcatgtgaa 156600
atgcagtgga agtgatatga gcttatttga agatgatatt caattaaacg agcatcaagt 156660
tgcttggtat tcaaaagatt ggacagctgt ccaatctgct gctgattctt ttaaggaaaa 156720
agctgaaaat gaattttttg aaataattgg agctattaat aataaaacta aatgctctat 156780
tgctcaaaaa gattattcaa aatacatggt tgagaatgca ttatcacaat ttccggagtg 156840
catgccagct gtatatgcta tgaatttaat tggatcaggt ttaagcgatg aagcccattt 156900
taattatctg atggctgctg ttcctcgggg taaaagatat ggtaaatggg caaaactggt 156960
tgaagattct accgaagtat tgattattaa gttacttgct aagcggtatc aagttaatac 157020
aaatgatgca attaactata aatcaattct tactaaaaat ggaaaacttc ctttagtatt 157080
aaaagaacta aaaggtttag tcacggatga ttttttgaaa gaagtgacta agaatgtaaa 157140
agaacagaaa caactcaaaa aactagcatt ggaatggtaa aatgattgaa attactctta 157200
aaaaacctga agattttctg aaagttaaag aaactttgac tcgtatggga attgctaata 157260
ataaagataa agttctgtat caatcctgtc atattctcca gaaaaaagga ctatactata 157320
tcgttcattt taaagaaatg cttcgtatgg atggtcgcca ggttgaaatg acagaagaag 157380
atgaagttcg tcgtgattcg attgcatggc tattagaaga ttggggactg attgaaatcg 157440
ttcctggtca aagaactttt atgaaagatt taactaataa cttccgagtt atttctttta 157500
aacaaaaaca tgaatggaaa ctcgttccta aatatacgat tggtaattaa tatgactgct 157560
ataactccgc aagaatacat ggcgtctctt aaagaaaaat ataatctttc tgcaacagaa 157620
acactttttg atttaccaga aaacctccaa ctaaaatttc aggtagaatt tcaaaaacta 157680
gttcatccag aacaaaaaca ttttacagca gtcgttaagt caattaatgc agatggaatg 157740
acaatttttc accgacaaat agtactaatt taagcaaggg gcttcggccc cttatttgga 157800
gtataatata tcaagagcct aataactcgg gctataaact aaggaatatc tatgaaagaa 157860
ttttatatct ctattgaaac agtcggaaat aacattgttg aacgttatat tgatgaaaac 157920
ggaaaggaac gtactcgcga agtagaatat cttccaacta tgtttagaca ttgtaaggaa 157980
gagtcaaaat acaaagacat ttatggtaaa aactgcgctc ctcaaaaatt tccatcaatg 158040
aaagatgcac gagactggat gaagcgaatg gaagacatcg gtctcgaagc tctcggtatg 158100
aacgatttta aactcgctta tatcagtgat acgtatggtt cagaaattgt ttatgaccga 158160
aaatttgttc gtgtagctaa ctgtgacatt gaggttactg gtgataaatt tcctgaccca 158220
atgaaagcag aatatgaaat tgatgctatc actcattacg attcaattga tgatcgtttt 158280
tatgttttcg accttttgaa ttcaatgtac ggttcagtat caaaatggga tgcaaagtta 158340
gctgctaagc ttgactgtga aggtggtgat gaagttcctc aagaaattct tgaccgagta 158400
atttatatgc catttgataa tgagcgtgat atgctcatgg aatatatcaa tctctgggaa 158460
cagaaacgac ctgctatttt tactggttgg aatattgagg ggtttgacgt tccatatatc 158520
atgaatcgcg ttaaaatggt tctcggtgaa cgtagtatga aacgcttctc tccaatcggt 158580
cgagtaaaat ctaaactaat tcaaaatgtg tacggtagca aagaaattta ttctattgat 158640
ggcgtatcta ttcttgatta tttagatttg tacaagaaat tcgcttttac taatttgccg 158700
tcattctctt tggaatcagt tgctcagcat gaaaccaaaa aaggtaaatt accgtatgat 158760
ggtcctatta ataaacttcg tgagactaat catcaacgat acattagtta taacatcatt 158820
gacgtagaat cagttcaagc aattgataaa attcgcgggt ttatcgatct agttttaagt 158880
atgtcttatt atgctaaaat gcctttttct ggtgtaatga gtcctattaa aacttgggat 158940
gctattattt ttaactcatt gaaaggtgaa cataaggtta ttcctcaaca aggttcgcac 159000
gttaaacaga gttttccggg tgcatttgtg tttgaaccta aaccaattgc tcgtcgatat 159060
attatgagtt ttgacttgac gtctctgtat ccgagcatta ttcgtcaggt taacattagt 159120
cctgagacta ttcgtggaca atttaaagtt catccaattc atgaatatat cgcaggaaca 159180
gctcctaagc caagtgatga atattcttgt tctccgaatg gatggatgta tgataagcac 159240
caagaaggta tcattccaaa ggaaatcgct aaagtatttt tccagcgtaa agactggaaa 159300
aagaaaatgt tcgcggaaga aatgaatgcc gaagctatta aaaagattat tatgaaaggc 159360
gcagggtctt gttcaactaa accagaagtt gaacgatatg ttaagttcag tgatgatttc 159420
ttaaatgaac tatcgaatta cgcagaatct gttcttaaca gtctgatcga agaatgtgaa 159480
aaagcagcta cacttgctaa cacaaatcag ctgaaccgta aaattcttat taacagtctt 159540
tatggtgctc ttggtaatat tcatttccgt tactatgatt tgcgaaatgc tactgctatc 159600
acaatttttg gtcaagtcgg tattcagtgg attgctcgta aaattaatga atacctgaat 159660
aaagtatgtg gaactaatgg tgaagatttc atcgcagcag gtgatactga ttcagtatat 159720
gtctgtgtag ataaagttat tgaaaaagta ggtcttgatc gctttaaaga acaaaatgat 159780
ttagttgaat tcatgaatca gtttggtaag aaaaagatgg aacctatgat tgatgttgca 159840
tatcgtgagt tatgtgacta tatgaataac cgcgagcatc tgatgcatat ggaccgtgaa 159900
gctatttctt gtcctccgct tggttcaaag ggtgttggtg gattttggaa agcgaaaaaa 159960
cgttatgctc tgaacgttta tgatatggaa gataagcgat ttgctgaacc acatctaaaa 160020
atcatgggta tggaaactca gcagagttca acaccaaaag cagtacaaga agctctcgaa 160080
gaaagtattc gtcgcattct tcaggaaggt gaagagtccg tccaagaata ctacaagaac 160140
ttcgagaaag aatatcgtca acttgactat aaagttattg ctgaagtaaa aactgcgaac 160200
gatatagcga aatatgatga taaaggttgg ccaggattta aatgcccgtt ccatattcgc 160260
ggtgtgctaa cttatcgtcg agctgttagt ggtctgggtg tagctccaat tttggatgga 160320
aataaagtaa tggttcttcc attacgtgag ggaaatccat ttggtgacaa gtgcattgct 160380
tggccatcgg gtacggaact tccaaaagaa attcgttctg atgtgctatc ttggattgac 160440
cactcaactt tgttccaaaa atcgtttgtt aaaccgcttg caggtatgtg tgaatcggct 160500
ggcatggact atgaagaaaa agcttcgtta gacttcctgt ttggctgata gaataaatct 160560
agggacctcc aggtcccttt ttcatacaag taatataaat ctatacttat gaaaaagaga 160620
tgattctagg tcctgtaaat tcattaaaaa ttttttcaca aaacggttta catctctgtt 160680
cttccatggt actatacaac tatcaactga tacggatttg gagaataaaa tgaaaattgt 160740
ttatggttgt ttagcagcgt gtttagttgc attagcagtt gttctagttg cattagcagc 160800
tgttccattt attgatattg aaaatgacac tcagaatgtg attgaatcta atactgttat 160860
tcacatgaat ggtaaagtat caacaaaaat tgatgataat cttcatatga atactaatgg 160920
aacgcttggt gttcaattag gtaatacctg tgtaagcact actggagtaa ttactacttg 160980
tatttgagga aattattatg aaaattgcta ttttggttat tacattgggt cttactgact 161040
gtgtagctca aggaccggta gtaaatcaat ctgatgtagg aaaaattgta aactgttcaa 161100
gcaaatttta taatcctaac gtcaagtgtt ataaagaagc tccaaaacag acagtagaac 161160
aaatgcaggc gaattttgac gaagctattc gtccagatga atctgctcaa gcatatcgta 161220
attcagatgt aattacacgc gaagaaaaaa ttgaaaacta ctgcgccgaa ctttgggcta 161280
attgggctaa taattaccaa tggcgtacag gtaaaaatgc tccgatggag tatgtagtga 161340
attcttataa ttcatgtgta aaaaatttga ctaagtgagg aaaacatgga aactttagta 161400
gcaggttcaa tttttatggt tttagtttca ggcgtgttgg ctatcattat atacatgctt 161460
ccgtggttca tcgccttgat gcgtgggtca aaatcgacag taggaatctt tttcacatct 161520
ttactgttta attggtcaat tattggttgg tttattacat ttatttggtc aattgcgggt 161580
gaaactaaaa aatctgcaca accgaatcaa gtaattatca tcagagagaa ggaatgaaaa 161640
gcaaaatttt agcagtattg cttttaatct tgatgattat aataagtata tactatagcg 161700
taacggttcc ttgtatgatt ccgacactta ttataggttg gggtttatta ctgttacaag 161760
ttaaatatga atgtatcaat tgaggtttaa atgattagtg actctatgac agttgaagaa 161820
atccgtcttc atttggggct tgcattaaag gaaaaagatt tcgtagttga taaaactggc 161880
gttaaaacta ttgaaattat tggcgcatca tttgtagcag atgaaccgtt tatttttggc 161940
gctcttaatg atgaatacat tcagcgtgaa cttgaatggt ataaatctaa aagtttgttt 162000
gttaaagata ttccgggtga aacaccgaag atttggcaac aggtagcatc ttctaaaggc 162060
gaaattaatt cgaattatgg ttgggccatc tggtcagaag ataactatgc ccaatatgat 162120
atgtgtttag ctgaacttgg tcaaaatcct gattctcgac gcggtatcat gatttatact 162180
cgtccatcca tgcaatttga ctacaataaa gatggtatgt cagatttcat gtgtacgaat 162240
acagtacagt acctgattcg tgataagaaa gtcaatgcgg ttgttagcat gagaagcaat 162300
gattgctggg caggctatcg taatgattat gcttggcaaa aatacgtact agataaatta 162360
gtatctgatt tgaatgcagg cgacccatcg cggcaatata aagcaggttc tattatatgg 162420
aacgttggaa gtcttcatgt gtacgaaaat cagttttatt tagttgacca ttggtggaac 162480
accggtgaga ctcatattgc taaaaaggat tatactggaa aatggaagta aatgtgccac 162540
atgtttataa gtataaacat cctaaaacta aaaagtggta tataggaagt catgatggtc 162600
acaacccgaa ttatgatggt tcgggtgtag tttggcaaca tgctaaaaag aaatatggaa 162660
taaaatcctt taataaagaa atattatatg aaggaccaat gtttagacag gttgaagaaa 162720
ttattttaac ttgtttagat gctgctaatt gtccggattc atataattta aagaatgaag 162780
catggggagg aagttttcca ggcaaattaa atggaatgta cggtaaaaaa ctatctccag 162840
aagaaagata taagtgcgga aatgcctttc gtggaatcaa gcgtcctgat cattctaaaa 162900
gaatgaaagg cgaaggtaat ccaatgtatg gtaaaaatga gcaggcatat ggaattataa 162960
atcgagccaa ggaaaattct ggtaaaactt atgaagaaat ttttggcgta gaaaaagcta 163020
aaataattaa agaaacgatg tctaaaaatc gtaaaggaaa acctcataat ttgatagaaa 163080
aaatatgtcc gcattgcgga ctaaaaggac gtgggccaaa tatgacaaga taccattttg 163140
acaaatgtaa ggcacttaaa tgattcaatt cgtaattcca agttatcagc gtgtcggggc 163200
agtttctgcc cttaatatgt ttccgactga ttatgaaccc catattgtag tgcgtgaaca 163260
tgaagaaaaa gtttattatg atgcttatgg gtctagagct aaaattatag ctattcctga 163320
tgatgttaat ggaattgccg gtactcgtaa agcaattact gatatgtatg caggtcaacg 163380
aatctggatg attgacgatg atactactat tcgtatgagt tcaatacgaa agagagacga 163440
taaacggcgc gtagataaaa ttaatcaatt aactcgtgaa cagttctatg aattgattca 163500
atacgttgaa gatgctatgg attgcgggta ttatcacggt catgctcgtc taccaatttt 163560
taaaattact tcatcttggg gtaattatcg tgaaaactca tatggattca cgaatacatg 163620
gtatgacctc ggaaaactta cggcagaaca aattgggtat ggaaaaattg atttatgcga 163680
agatatgtat gcatttctca atttaattaa tcaaggttat ccgcatttgg ccttgttcaa 163740
atatctagtt gtatctggaa aatcacacgc tcccggtgga tgtagttcaa ttcgtagtaa 163800
ttctaaacat aatagagcgc ttgagcaaat caatagagag tttccagagc aagctcgttg 163860
gaaaacttca aatattgaaa aacgaaaatc gttgggtgaa gaagacgagc cattaaaggt 163920
tcttcgcatg tgtgtttcgc gtaaagaaaa atcagaagca tttcataagt ttaatgctat 163980
tcatccaata gcagttgatt aatgcctaaa tttattgtgt tataattact ttatctttaa 164040
ccagtgagga aaatataatg atgcctatgg aaaaaatgaa tgtctattgc agatttaaaa 164100
tcccgtttga ttaaagcttc cacttctaaa atgactgctg aactgactaa agcaaagcaa 164160
gttctttaat gaaaaggatg tggttcgtac taaaattcca atgctgaata ttgcaattag 164220
cggtgcgatt gatgacatga aaagacataa agaaaagaaa tataattata cttatgttat 164280
aactaattta gttaataata aaatttacta tggaactcat tcaaccgatg atttaaatga 164340
tggttatatg ggatcaggaa ctttattagc acaagccaag aaaaagtatg gtaagaaaaa 164400
ttttaattta agcattcttg ggttttataa agattttaaa tcagcccgtg atgctgaaag 164460
agaattagta acaatagatg tggtaaatga tcctatgact tataatttaa aaattggtgg 164520
agagggtggt agaagaattg gttatagagt ttcatcagaa accaaagaaa aaatttcaaa 164580
agctcaaaaa ggaaaaccaa aacatcttgg atttagtgat gtttgccgga aagcccagct 164640
aggcaaaaag cagtcagaag aaactaaagc aaaacgaaaa gaagctttgc ttaataatcc 164700
atatggttat aatagaaata aaccatcaca taaacgtgac ccaataatgt gggataacat 164760
tgaaaagatt aaagaaatat gggaaaactc tggaaaaccc ggtgctatta agcttaaaaa 164820
attagcaatt gaagctggat ttccaaataa atcttatgca agaatgctcg aagtatttcg 164880
tggaacaaga acactactat aaggtattat atgtctgatt taaaatctcg tttgattaaa 164940
gcttctactt ctaaattgac tgcagaatta acagcatcta aattctttaa tgaaaaagat 165000
gtagttcgaa caaaaattcc tatgatgaat attgcacttt ctggtgaaat tactggtggt 165060
atgcaatctg gtctgttaat tttggcaggt ccatcaaaat catttaaatc aaactttgga 165120
ttaacaatgg tgtcatctta catgcgtcaa tatcctgatg cagtatgttt gttttatgat 165180
agtgaatttg gtattactcc tgcttatttg cggtctatgg gagtcgatcc agaacgagta 165240
attcatactc cggttcaatc acttgagcaa ttacgtattg acatggttaa tcaattggat 165300
gcaattgaac gtggcgaaaa ggtagtcgtt tttatcgatt cacttggtaa cttagcttct 165360
aagaaagaaa ctgaagatgc tttaaatgaa aaagttgtta gtgatatgac tagagctaaa 165420
acaatgaaaa gcttatttcg tatcgtaact ccctatttta gtactaaaaa tattccatgt 165480
attgctatta accatacata cgaaacacaa gaaatgttta gtaaaacagt tatgggaggt 165540
ggtactggac cgatgtattc ggctgatact gtattcatta tcggtaaacg tcagattaaa 165600
gatggttctg atcttcaggg gtatcaattt gttctaaatg tagaaaaatc tcgtaccgtt 165660
aaagaaaaaa gtaaattctt tattgatgtt aaatttgacg gtggtatcga tccttattct 165720
ggattgttag atatggctct agaattagga tttgtagtaa aaccaaaaaa tggctggtat 165780
gctcgtgaat ttcttgatga agaaaccggc gagatgattc gcgaagaaaa atcttggcgt 165840
gcaaaagata ccaactgcac tacattctgg ggtcctttat ttaagcatca accattccga 165900
gatgctatta aacgtgctta tcagttaggt gctattgata gtaatgaaat tgttgaagct 165960
gaagtcgacg aattgattaa ctcaaaggtt gaaaaattta aatctccaga aagtaaaagt 166020
aaatcagctg ctgatttaga aactgaccta gaacagttaa gtgatatgga agaatttaat 166080
gaataaagat gatttagatt tagatctaga aattatcgac gaatccccct cttcggaggg 166140
ggaagaagaa agaaaagaac gcctttttaa tgaatctctt aagataatta aatctgccat 166200
ggaaaatgtt atccaggaga ttgtcattaa actagaagac ggttctacac acattgtgta 166260
tgtgacaaaa ttagattggg ttgatggaaa agtcgtaatg gactttgctg ttcttgacca 166320
agaaagaaaa gctgagttag ctcctcatgt agaaaaatgt attacaatgc aactacaaga 166380
tgcatttaat aaaaggtcaa agaaaaaatt taaattcttt taaggagtaa gtgtggtaga 166440
aattattctt tcccatctca tatttgatca agcttatttt tcaaaagttt ggccatatat 166500
ggattcagaa tattttgaaa gtggtccagc taaaaataca ttcaaattaa ttaaatctca 166560
tgttaatgag taccatagcg ttccatctat taatgcgtta aatgttgcat tagaaaatag 166620
ttcatttact gaaacagaat attctggtgt aaaaacactt atttcgaaac tagccgattc 166680
tccagaagac catagctggt tagtaaaaga aacagaaaaa tatgttcagc aaagggcgat 166740
gtttaatgct acgtctaaaa taattgaaat tcaaactaat gctgagcttc ctccggaaaa 166800
acgaaataag aaaatgccag atgtaggtgc tattcctgac atcatgcgcc aagcattatc 166860
aatttcattt gatagttacg ttggtcatga ttggatggat gactacgaag cacgttggct 166920
atcttatatg aataaagctc gtaaggttcc atttagactc aaaattctaa ataaaattac 166980
taaaggtgga gctgaaactg gaacactgaa cgttttaatg gctggtgtta acgtcggtaa 167040
gtcattagga ttgtgttcat tggcagcaga ttatttgcag ctcggacata atgttcttta 167100
catttccatg gaaatggcag aagaagtctg tgctaagcgt attgatgcta atatgcttga 167160
tgtttctctt gatgacattg atgacgggca tatttcttac gccgagtata aaggaaaaat 167220
ggaaaaatgg cgtgagaaat ctacccttgg tcgtttaatc gttaagcaat atcctactgg 167280
tggagcagac gctaatacat ttcgatcgct tttaaacgaa ttaaaactca agaagaattt 167340
tgttccaaca atcattattg tcgactatct aggtatttgt aaatcttgcc gcatcagggt 167400
ttactcagaa aatagttaca caactgttaa agctattgca gaggaattgc gtgctcttgc 167460
tgttgaaacc gaaactgttc tttggactgc agcacaggtt ggtaaacaag cttgggattc 167520
ttctgatgtt aacatgagcg atatcgcaga atctgccggt cttccagcaa cagccgattt 167580
tatgcttgca gtcattgaaa ccgaggagtt agcagctgct gaacaacaac tcattaagca 167640
aatcaaatca cgatatggtg ataagaataa atggaataag tttttgatgg gtgttcaaaa 167700
aggaaatcag aaatgggtag aaattgaaca agattctact ccaactgaag tgaacgaagt 167760
agcaggttca cagcagattc aggctgaaca gaatcgctat caaagaaacg aatctgctcg 167820
agctcagtta gatgctttgg caaatgaatt aaaattttag tttacaagcc aacaagacta 167880
tggtatagta gtcttgttgg ttaaatgagg agattgttgt ggaattggta aaggtagttt 167940
ttatggggtg gtttaagaac gaaagcatgt ttactaaaga aatcacaatg atgaaagatg 168000
acgttcaatg ggctactaat caatatgctg aagttaataa agcgctagtt aaagctttca 168060
ttgatgacaa gaaagtatgc gaagtggatt gccgaggata atatgcatat tgttttattt 168120
aaacctactc catataacgt caggaaaaat actcaattca aagcacttat tgcagatacg 168180
tgggaattag tattagatat tccggcagaa gaaagccctc catttggtcg agtggaattt 168240
attaagtttg ctgtgcgccc tacgaagcga cagattcgtc aatgcaaaag atactttcgt 168300
aaaatcgtca agttagagaa acagtttgta acatgtgatt atgcagaagt tttaaaatag 168360
ctgtttactt ttattagaaa ttgagatact ataaacataa actactgagg agattatcat 168420
gaaaaaattt atctttgctg caatttttgc tttatcttct tgcgctgctc agcctgctat 168480
ggcgggttat gacaaagatt tgtgtgaatg gtctatgact gcagatcaga ctgaggttga 168540
aactcaaatt gaagcagata ttatgaatat cgttgagcgt gatcgtcctg aaatgaaagc 168600
tgaagtgcaa aaacaactta agtctggcgg tgtaatgcag tataattatg ttctgtattg 168660
cgataaaaac tttaataata aaaatatcat cgctgaagtg gtaggtgagt aattagaggt 168720
tagtatgtac agttctgaat tttcatattt aaaaatggaa aaaatttcat acgattttat 168780
agatgaaaag gtttattaca gtttccatga accacgtttt aatagtgagg ttgggtttat 168840
tgtagtaaaa gacaatttca ttttaaaaat atattcggca ttaaaggatt ttcactacga 168900
aaatattaac ctaaaatttg ataaagaaaa cgttcgtaat tgtgcagtaa caattacagg 168960
aaataaaggt acatgcgtta tgctatctga tgaaattaat gatttgctaa atgatgcaga 169020
aaaagttgct attccatcga ttgatgacca aatttttaat gcttttatga atagaggtta 169080
atatgaaaac atataaagaa tttattaaag aagatatggt agctggagat tcaggtggta 169140
atcctgaaaa tatctccact ggaacaacgt caggcgctgt agtaaataaa ggtcctgaac 169200
agattcctaa aaagaaaaaa gaggaatcta aagaaaaaga agagtaaaaa tgtcatcaat 169260
accttggatt gataatgagt ttgcgtgccg tgcattggct catttaccta aattcgcaca 169320
agtaaataat agttcaactt ttaaattacg gtttagatgc cctgtttgcg gagattcaaa 169380
aaccgatcaa aataaagccc gtggatggta ttatggcgat aataatgaag gaaatattca 169440
ttgttataac tgtaactatc atgcaccaat tggaatatat ttaaaggagt ttgaacctga 169500
tttatatcgt gagtatatct ttgaaataag aaaagaaaaa ggtaaaagtc gtccagtaga 169560
aaaacctaaa gaacttccta aacagcctga gaagaaaata attaaatctc ttccgtcatg 169620
cattagatta gataaacttg cggaagacca tccaattata aaatatgtaa aagctcgttg 169680
tattccaaag gataaatgga aatatctttg gtttacgacc gaatggc 169727

Claims (5)

1.一种从自然界分离并能够特异性地杀死产志贺毒素F18型大肠杆菌的肌尾噬菌体科噬菌体Esc-COP-1,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC12662BP)。
2.一种用于预防和治疗产志贺毒素F18型大肠杆菌感染的组合物,其包含权利要求1所述的噬菌体Esc-COP-1作为活性成分。
3.根据权利要求2所述的用于预防和治疗产志贺毒素F18型大肠杆菌感染的组合物,其中所述组合物用于制备饲料添加剂、饮用水添加剂或消毒剂。
4.一种预防和治疗产志贺毒素F18型大肠杆菌细胞感染的方法,其包括向受试者施用权利要求2或权利要求3所述的包含噬菌体Esc-COP-1作为活性成分的组合物的步骤。
5.根据权利要求4所述的预防和治疗产志贺毒素F18型大肠杆菌细胞感染的方法,其中所述组合物以饲料添加剂、饮用水添加剂或消毒剂的形式给药到受试者。
CN201580071183.9A 2014-12-30 2015-12-28 新型产志贺毒素F18型大肠杆菌噬菌体Esc-COP-1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途 Active CN107208068B (zh)

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US20170340686A1 (en) 2017-11-30
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