KR20230112700A - 방법 - Google Patents

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KR20230112700A
KR20230112700A KR1020237021517A KR20237021517A KR20230112700A KR 20230112700 A KR20230112700 A KR 20230112700A KR 1020237021517 A KR1020237021517 A KR 1020237021517A KR 20237021517 A KR20237021517 A KR 20237021517A KR 20230112700 A KR20230112700 A KR 20230112700A
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bacteria
phage
clostridium
composition
therapeutic
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크리스토프 렌 레오나드 카리테
안토니오 페르난데즈 메다르데
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4디 파마 레온, 에스.엘.유.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

본 발명은 치료용 박테리아를 포함하는 조성물을 분석하기 위한 방법에 관한 것이며, 여기서 방법은 (a) 치료용 박테리아의 성장을 선택적으로 저해하는 조건 하에서 조성물을 배양하는 단계, 및 (b) 단계 (a)의 배양된 조성물을 분석하여 원치 않는 유기체가 조성물에 존재하는지 여부를 결정하는 단계를 포함한다. 본 발명은 또한 치료용 박테리아의 성장을 저해시키는 데 사용하기에 적합한 박테리오파지에 관한 것이다.

Description

방법
본 발명은 치료용 박테리아를 포함하는 조성물을 분석하기 위한 방법에 관한 것이다. 본 출원에서, 치료용 박테리아는 포유동물, 바람직하게는 인간에서 질환 또는 병태의 예방, 치료 또는 치유에 사용되는 살아있는 박테리아로 정의된다. 본 발명은 또한 이러한 방법에 사용하기 위한 파지뿐만 아니라 이러한 방법을 수행하기 위한 키트에 관한 것이다.
포유동물 장은 자궁 내에서 멸균 상태인 것으로 생각되지만 출생 직후 매우 다양한 모체 및 환경 미생물에 노출된다. 이 후, 장내 미생물총을 제공하는 미생물 콜로니화 및 천이의 역동적인 기간이 있다. 장내 미생물총의 조성은, 특히 초기 생애 동안 분만 방식(예를 들어, 제왕절개 또는 자연 분만을 통함), 환경, 식이 및 숙주 유전자형과 같은 요인에 의해 영향을 받는다. 이후에, 장내 미생물총은 안정화되어 성인과 유사하게 된다. 인간 장내 미생물총은 본질적으로 2가지 주요 박테리아 문(bacterial phyla), 즉, 박테로이데테스(Bacteroidetes) 및 피르미큐테스(Firmicutes)에 속하는 약 500 내지 1,000가지 상이한 계통형(phylotype)을 포함한다. 내장의 미생물 콜로니화로 인해 발생하는 성공적인 공생 관계는 매우 다양한 대사, 구조, 보호 및 기타 유익한 기능을 제공한다. 콜로니화 내장의 향상된 대사 활성은 그렇지 않으면 소화되지 않는 식이 성분이 분해되어, 숙주에게 중요한 영양 공급원을 제공하는 부산물을 방출한다.
유사하게, 장내 미생물총의 면역학적 중요성은 잘 인식되어 있으며 공생 미생물의 도입에 따라 기능적으로 재구성되는 손상된 면역계를 갖는 멸균 동물에서 예시된다.
장내 미생물총 조성의 극적인 변화는 염증성 장 질환(IBD)과 같은 인간 위장 장애에서 기록된 바 있다. 예를 들어, 클로스트리듐(Clostridium) 클러스터 XIVa 박테리아의 수준은 IBD 환자에서 감소되는 반면, 이. 콜라이(E. coli) 박테리아의 수는 증가하며, 이는 장내 공생균(symbiont)과 유해균(pathobiont)의 균형에 변화가 있음을 시사한다. 흥미롭게도, 이러한 미생물의 장내 세균 불균형은 또한 T-이펙터 세포 개체군의 불균형과도 연관된다.
특정 박테리아 균주가 포유동물 내장에 미칠 수 있는 잠재적인 긍정적 효과를 인식하여, 다양한 박테리아 균자가 다양한 질환의 예방, 치료 및 치유에 사용하기 위해 제안되었다. 생리적 병태를 치료하기 위한 살아있는 박테리아의 사용에 대한 개시의 예는 다음을 포함한다: EP-A-1 280 541(인간 과민성 대장 증후군을 포함하여, 다양한 병태의 치료에서 수소영양(hydrogenotrophic) 유기체의 사용을 개시함); EP-A-1 448 995(염증성 질환의 치료에서 박테로이데스 테타이오타미크론(Bacteroides thetaiotamicron)의 사용을 개시함); EP-A-2 763 685(면역조절제로서 로제부리아 호미니스(Roseburia hominis)의 사용을 개시함); WO 2017/085520(항암 요법으로서 엔테로코커스 갈리나룸(Enterococcus gallinarum)의 사용을 개시함); 및 EP-A-3206700(중증 천식을 포함하여 다양한 자가면역/염증성 병태의 치료에서 비피도박테리움(Bifidobacterium)의 사용을 개시함).
이러한 살아있는 박테리아는 생균치료제(Live Biotherapeutic Products: "LBP")로서 US FDA에 의해 분류되는 약제 부류에서 활성 성분으로 사용된다. 2012년 2월에 FDA가 발표하고 2016년에 업데이트된 지침(Guidance for Industry: Early Clinical Trials with Live Biotherapeutic Products : Chemistry, Manufacturing, and Control Information)에서, LBP는 1) 살아있는 유기체, 예컨대, 박테리아를 포함하고; 2) 인간의 질환 또는 병태의 예방, 처리, 또는 치유에 적용 가능하며; 3) 백신이 아닌, 생물학적 제제로 정의된다. 또한 프로바이오틱 제품과 달리, LBP는 규제 기관에 의해 약제와 동일한 엄격한 조사를 받는다고 FDA 지침 문서에 언급되어 있다.
LBP의 개발자가 직면한 한 가지 문제는 치료용 박테리아 배양물의 오염이다. 치료용 박테리아 또는 치료용 박테리아들 이외의 유기체의 세포가 하나라도 존재한다면, 이들 유기체는 치료용 박테리아 또는 치료용 박테리아들과 함께 기하급수적으로 성장할 수 있다. 분명히, 이러한 다른 유기체가 병원성이라면, 이러한 유기체의 존재는 허용될 수 없다. 이러한 유기체는 또한 다른 이유로 문제가 될 수 있으며, 예를 들어 이러한 유기체는 LBP에 존재하는 것이 허용될 수 없는 대사산물을 생산하거나 화합물을 발현할 수 있다. 이들 유기체는 또한 치료용 박테리아 또는 치료용 박테리아들의 성장 프로파일을 왜곡하여, 상업적 규모로 LBP를 제조할 때 우려되는 차선의 생산 공정으로 이어질 수 있다.
당업자라면 원치 않는 유기체(예를 들어, 치료용 박테리아 이외의 박테리아 균주, 특히 병원성 박테리아)의 존재를 확인하기 위해 박테리아 개체군을 평가하기 위한 접근법을 알고 있을 것이지만, 이러한 접근법이 항상 적절한 것이 아닐 수 있다. 예를 들어, 원치 않는 병원성 유기체가 대량의 치료용 박테리아 개체군을 포함하는 바이오매스에 낮은 수준으로 존재하는 경우, 원치 않는 병원성 유기체의 존재를 검출하는 것이 어려울 수 있다. 치료용 박테리아가 발효 배지에서 영양분에 대해 원치 않는 유기체와 성공적으로 경쟁하는 데 효과적인 이러한 상황이 발생하여, 치료용 박테리아 개체군의 크기와 비교하여 원치 않는 유기체의 작거나 매우 작은 개체군을 생성할 수 있다.
표면적으로는 원치 않는 유기체 개체군의 크기를 작거나 매우 작게 유지하는 것이 매력적으로 보일 수 있지만, 이는 실제로 문제가 있다. 상기 설명된 바와 같이, 약제학적 제품으로 승인되려면, LBP는 의료 규제 기관의 엄격한 평가를 통과하여야 한다. 예를 들어, 유럽 약전(챕터 2.6.38)은 LBP가 치료용 박테리아이외의 박테리아를 완제 의약품의 그램당 1000 콜로니 형성 단위(CFU) 미만으로 포함하는 것을 요구한다. 추가적으로, 또한 클로스트리디아(Clostridia) 및 살모넬라(Salmonella) 종 및 스타필로코커스 아우레우스(Staphylococcus aureus), 슈도모나스 아에루기노사(Pseudomonas aeruginosa) 및 에쉬리키아 콜라이(Escherichia coli) 종으로부터 임의의 검출 가능한 병원성 유기체의 부재를 입증하는 것이 필요하다. 규제 과정에서, LBP 개발자가 이러한 요구 조건이 준수되었음을 최종적으로 입증할 수 있는 것이 중요하다.
추가적으로 또는 대안적으로, 원치 않는 유기체가 해당 제품의 발효/제조 동안 노출되는 조건에 의해 성장이 억제되므로 상기 원치 않는 유기체가 최종 제품에 낮은 수준으로 존재하더라도, GI 관으로 전달될 때(LBP의 대부분이 그러함) 장내 조건은 원치 않는 유기체가 번성하고 개체군이 기하 급수적으로 증가하도록 할 수 있다.
또한, 높은 수준으로 존재하는지 낮은 수준으로 존재하는지 여부에 관계 없이, 원치 않는 유기체는 최종 제품 또는 GI 관에 존재하는 것이 규제 관점에서 바람직하지 않거나 허용 가능하지 않을 수 있는 대사산물을 생산하거나 화합물을 발현할 수 있다. 원치 않는 유기체의 개체군 크기가 작을 수 있는 경우에도, 원치 않는 유기체가 생산하는 대사물질/생성물은 허용 가능하지 않은 수준으로 축적될 수 있다.
문헌[Viruses 2015, 7, 6675-6688, Dreher-Lesnick et al.]에는, 생균치료제(LBP)에 대한 개선된 순도 분석에 사용하기 위한 파지 라이신 LysA2의 개발이 개시되어 있다. 저자는 모두 FDA의 백신 연구 및 검토 사무소(Office of Vaccines Research and Review) 출신이다. 상기 논문은 저자가 개발한 공정이 장래에 유용할 수 있음을 나타내지만 제시된 데이터는 FDA의 자체 요구 사항을 충족할 것임을 나타내지 않는다. 예를 들어, 저자는 "LBP에 대한 순도 분석에 사용하기 위한 강력한 시약으로서 Lys2 및 다른 라이신을 개발하기 위해서는 추가적인 최적화가 필요하다"고 결론을 내렸고, Lys2의 성공적인 사용은 높은 수준의 이. 콜라이 또는 에스. 아우레우스(S. aureus)가 스파이킹된 엘. 젠세니(L. jensenii)의 콜로니에서만 입증되었다.
또한, 해당 논문에 보고된 공정은 정제된 박테리아 배양물에 대해 수행된다. 그러나, LBP의 순도 평가에 대한 요구 사항은 최종 완제 의약품, 즉, 환자에게 투여될 조성물에 대해 입증되어야 하므로, Dreher-Lesnick에 의해 보고된 공정은 최종 완제 의약품과 관련하여 예시되지 않았기 때문에 상기 공정은 규제 의무 준수를 입증하기에 충분하지 않을 것이다.
WO 2014/153194는 특히 조성물에서 오염 물질을 풍부하게 하는 것에 관한 것이다. 여러 가지 대체 및 추론 분석이 제안된다. 그러나, 이들 분석 중 어느 것의 작업예도 제공되지 않으며, 이 개시내용은 숙련된 종사자가 LBP에서 오염 물질을 선택적으로 풍부하게 하는 것을 가능하게 하지 않는다.
따라서 특히 원치 않는 유기체가 낮은 수준으로 존재할 때 원치 않는 유기체를 식별하기 위해 치료용 박테리아를 포함하는 약제학적 조성물을 분석하기 위한 개선된 공정에 대한 필요성이 존재한다.
본 발명은 오염물질이 낮은 수준으로 존재하거나 오염 물질의 성질이 알려지지 않은 경우에도 원치 않는 미생물을 빠르고 정확하게 검출할 수 있는 새롭고 개선된 분석 방법을 제공한다.
일 실시형태에서, 치료용 박테리아를 포함하는 조성물을 분석하기 위한 방법을 제공하되, 해당 방법은 다음 단계들을 포함한다:
(a) 치료용 박테리아의 성장을 선택적으로 저해하는 조건 하에서 조성물을 배양하는 단계; 및
(b) 단계 (a)의 배양된 조성물을 분석하여 원치 않는 유기체가 조성물에 존재하는지 여부를 결정하는 단계.
본 발명자들은 치료용 박테리아 성장의 선택적인 저해가 유리하게 미생물 조성물에서 임의의 원치 않는 유기체의 분석을 가능하게 하고 용이하게 한다는 것을 발견하였다. 일 실시형태에서, 치료용 박테리아의 성장만 선택적으로 저해된다. "선택적으로 저해되는"은 바람직하게는 치료용 박테리아의 성장만 저해되는 실시형태를 지칭한다. 일부 실시형태에서, 하나 이상 오염 물질의 성장이 또한 저해될 수 있다. 예를 들어, 치료용 박테리아의 성장은 하나 이상의 원치 않는 유기체의 성장이 저해되는 것보다 적어도 5배 초과, 예컨대, 하나 이상의 원치 않는 유기체의 성장보다 적어도 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 20, 25, 30, 35, 40, 45, 또는 50배 초과로 저해될 수 있다. 일 실시형태에서, 원치 않는 유기체의 성장은 저해되지 않는다. 일 실시형태에서, 임의의 원치 않는 유기체의 성장은 저해되지 않는다.
"선택적인 저해"란, 치료용 박테리아의 성장이 원치 않는 유기체의 성장 저해와 비교하여 배양하는 단계 (a)에서 우선적으로 저해됨을 의미한다. 예를 들어, 단계 (a)의 치료용 박테리아의 성장 저해는 원치 않는 유기체의 성장 저해보다 적어도 2배, 적어도 3배, 적어도 4배, 적어도 5배, 적어도 10배, 적어도 20배, 적어도 50배 초과일 수 있다. 당업자가 이해할 바와 같이, 이는 선택적인 성장 조건 전의 성장 속도에 대해 평가되어야 한다. 바람직하게는, 단계 (a)에서 임의의 원치 않는 유기체에 대한 성장 속도는 치료용 박테리아가 성장하는 속도보다 적어도 2배 초과, 적어도 3배 초과, 적어도 4배 초과, 적어도 5배 초과, 적어도 10배 초과, 적어도 20배 초과, 또는 적어도 50배 초과이다. 이 문맥에서 "원치 않는 유기체"에 대한 언급은 단일의 원치 않는 유기체(예를 들어, 단일 바이러스 종)를 지칭할 수 있거나 다수의 원치 않는 유기체를 언급할 수 있다. 예를 들어, 치료용 박테리아의 성장 저해는 조성물 내의 모든 원치 않는 유기체에 대해 또는 원치 않는 유기체 중 단 하나에 대해 저해될 수 있다.
분석 단계가 적어도 하나의 원치 않는 유기체가 조성물에 존재한다고 결정하는 경우, 방법은 하나 이상의 원치 않는 혐기성 또는 호기성 박테리아를 식별하는 단계를 포함할 수 있다. 박테리아는 병원성 박테리아, 예컨대, 클로스트리디아 및 살모넬라 속의 박테리아, 예를 들어 클로스트리듐 디피실(Clostridium difficile), 클로스트리듐 테타니(Clostridium tetani), 또는 살모넬라 엔테리카(Salmonella enterica) 종의 박테리아, 또는 스타필로코커스 아우레우스, 슈도모나스 아에루기노사 및 에쉬리키아 콜라이 종의 박테리아 등, 또는 이러한 원치 않는 유기체의 혼합물일 수 있다.
표현 "원치 않는 유기체"는 치료용 박테리아 이외의 조성물 중 임의의 유기체를 지칭한다. 일부 실시형태에서, 원치 않는 유기체는 원치 않는 박테리아 또는 원치 않는 박테리아들이다. 원치 않는 유기체는 또한 포유동물 병원체, 예컨대, 인간 병원체인 임의의 박테리아일 수 있다. 표현 "원치 않는 유기체"는 본 명세서의 맥락에서 "오염 물질" 또는 "오염 유기체"와 호환 가능하다. 일 실시형태에서, 적어도 하나의 원치 않는 유기체는 이. 콜라이 또는 에스. 아우레우스가 아니다. 가장 바람직한 실시형태에서, 원치 않는 유기체는 조성물에 의도적으로 첨가되지 않았다.
원치 않는 유기체가 세포 유기체인 경우, 배양하는 단계 이전에 미생물 조성물에서 치료용 박테리아의 세포 수 대 하나 이상의 원치 않는 유기체의 세포 수의 비율은 1,000:1 이상, 10,000:1 이상, 100,000:1 이상, 1,000,000:1 이상, 10,000,000:1 이상, 100,000,000:1 이상, 1,000,000,000:1 이상, 10,000,000,000:1 이상일 수 있다.
선택적 저해
치료용 박테리아의 성장의 선택적 저해는 배양 배지의 pH, 온도 및/또는 이온 강도를 선택함으로써 달성될 수 있다. pH 및 온도와 박테리아 성장 사이의 관계는 잘 이해되어 있으며, pH 및/또는 온도를 제어하여 박테리아 성장을 제어하기 위한 방법은 잘 알려져 있다(예를 들어, 문헌["Modelling the combined effect of temperature and pH on the rate coefficient for bacterial growth", Davey, International Journal of Food Microbiology (1994) 23 (3-4), pp 295-303] 참조). 또한, 성장 배지에서 염의 농도를 제어하는 것은 특정 박테리아의 성장을 저해하여, 따라서 민감한 박테리아의 성장을 선택적으로 저해하는 것으로 알려져 있다(예를 들어, 문헌["Bacterial culture through selective and non-selective conditions: the evolution of culture media in clinical microbiology", Bonnet et al., New Microbes New Infect (2020) 34: 100622] 참조).
실시형태에서, 본 발명의 방법에서 단계 (a)는 7 이하, 예를 들어, 6.5 이하, 6 이하, 5.5 이하, 5 이하, 4.5 이하, 4 이하, 3.5 이하, 3 이하, 또는 2.5 이하, 예를 들어 2.5 내지 6.5, 2.5 내지 6, 2.5 내지 5.5, 2.5 내지 5, 2.5 내지 4.5, 2.5 내지 4, 2.5 내지 3.5, 2.5 내지 3, 3 내지 6.5, 3 내지 6, 3 내지 5.5, 3 내지 5, 3 내지 4.5, 3 내지 4, 3 내지 3.5, 4 내지 6.5, 4 내지 6, 4 내지 5.5, 4 내지 5, 4 내지 4.5, 5 내지 6.5, 5 내지 6, 5 내지 5.5, 또는 6 내지 6.5의 pH에서 수행된다. 다른 실시형태에서, 단계 (a)≥ 8 이상, 예를 들어, 8.5 이상, 9 이상, 9.5 이상, 10 이상, 10.5 이상, 11 이상, 또는 11.5 이상의 pH에서 수행될 수 있다. 예를 들어, pH는 8.5 내지 11.5, 9 내지 11.5, 9.5 내지 11.5, 10 내지 11.5, 10.5 내지 11.5, 11 내지 11.5, 8.5 내지 11, 9 내지 11, 9.5 내지 11, 10 내지 11, 10.5 내지 11, 8.5 내지 10.5, 9 내지 10.5, 9.5 내지 10.5, 10 내지 10.5, 8.5 내지 10, 9 내지 10, 9.5 내지 10, 8.5 내지 9.5, 9 내지 9.5 등일 수 있다.
추가적으로, 또는 대안적으로, 단계 (a)의 온도는 10℃ 이하, 9℃ 이하, 8℃ 이하, 7℃ 이하, 6℃ 이하, 5℃ 이하, 4℃ 이하, 3℃ 이하, 2℃ 이하이도록 선택될 수 있다. 낮은 성장 온도가 선택되는 경우, 단계 (a)가 수행되는 성장 배지가 동결되지 않도록 조건이 선택될 필요가 있다는 것이 당업자에게 명백할 것이다. 따라서, 일부 실시형태에서, 온도는 0.5℃ 내지 10℃, 0.5℃ 내지 9℃, 0.5℃ 내지 8℃, 0.5℃ 내지 7℃, 0.5℃ 내지 6℃, 0.5℃ 내지 5℃, 0.5℃ 내지 4℃, 0.5℃ 내지 3℃, 0.5℃ 내지 2℃, 0.5℃ 내지 1℃, 1℃ 내지 10℃, 1℃ 내지 9℃, 1℃ 내지 8℃, 1℃ 내지 7℃, 1℃ 내지 6℃, 1℃ 내지 5℃, 1℃ 내지 4℃, 1℃ 내지 3℃, 1℃ 내지 2℃, 2℃ 내지 10℃, 2℃ 내지 9℃, 2℃ 내지 8℃, 2℃ 내지 7℃, 2℃ 내지 6℃, 2℃ 내지 5℃, 2℃ 내지 4℃, 2℃ 내지 3℃, 3℃ 내지 10℃, 3℃ 내지 9℃, 3℃ 내지 8℃, 3℃ 내지 7℃, 3℃ 내지 6℃, 3℃ 내지 5℃, 3℃ 내지 4℃, 4℃ 내지 10℃, 4℃ 내지 9℃, 4℃ 내지 8℃, 4℃ 내지 7℃, 4℃ 내지 6℃, 4℃ 내지 5℃ 등으로부터 선택되는 범위이도록 선택될 수 있다.
치료용 박테리아의 성장은 또한 더 높은 온도에서 저해될 수 있다. 따라서, 일부 실시형태에서, 단계 (a)의 온도는 50℃ 이상, 55℃ 이상, 60℃ 이상, 65℃ 이상, 70℃ 이상, 75℃ 이상, 80℃ 이상, 85℃ 이상, 또는 90℃ 이상이도록 선택될 수 있다. 끓는 점 초과에서 배양하는 것을 피하는 것이 바람직하다는 것은 당업자에게 명백할 것이다. 따라서, 일부 실시형태에서, 온도는 50℃ 내지 99℃, 55℃ 내지 99℃, 60℃ 내지 99℃, 65℃ 내지 99℃, 70℃ 내지 99℃, 75℃ 내지 99℃, 80℃ 내지 99℃, 85℃ 내지 99℃, 90℃ 내지 99℃, 50℃ 내지 95℃, 55℃ 내지 95℃, 60℃ 내지 95℃, 65℃ 내지 95℃, 70℃ 내지 95℃, 75℃ 내지 95℃, 80℃ 내지 95℃, 85℃ 내지 95℃, 90℃ 내지 95℃, 50℃ 내지 90℃, 55℃ 내지 90℃, 60℃ 내지 90℃, 65℃ 내지 90℃, 70℃ 내지 90℃, 75℃ 내지 90℃, 80℃ 내지 90℃, 85℃ 내지 90℃, 50℃ 내지 85℃, 55℃ 내지 85℃, 60℃ 내지 85℃, 65℃ 내지 85℃, 70℃ 내지 85℃, 75℃ 내지 85℃, 80℃ 내지 85℃, 50℃ 내지 80℃, 55℃ 내지 80℃, 60℃ 내지 80℃, 65℃ 내지 80℃, 70℃ 내지 80℃, 75℃ 내지 80℃, 50℃ 내지 75℃, 55℃ 내지 75℃, 60℃ 내지 75℃, 65℃ 내지 75℃, 70℃ 내지 75℃ 등으로부터 선택되는 범위이도록 선택될 수 있다.
예를 들어, 장내구균(enterococcal) 박테리아는 5 내지 65℃의 온도, 및 pH가 4.5 내지 10.0인 환경에서 생존하는 것으로 알려져 있고, 높은 염분 농도에서 생존할 수 있으며(문헌["The Ecology, Epidemiology, and Virulence of Enterococcus", Fisher and Phillips, Microbiology (2009) 155 (6), pp 1749-1757] 참조); 치료용 박테리아가 장내구균인 경우, 선택적 저해는 따라서 온도를 5℃ 미만으로 낮추고/낮추거나 pH를 4.5 미만으로 낮춤으로써 달성될 수 있다. 마찬가지로, 여러 종의 유산균, 예를 들어 락토바실러스(lactobacilli)는 매우 높은 pH에 대해 내성이 없으며(예를 들어, 문헌["Diversity and Mechanisms of Alkali Tolerance in Lactobacilli", Sawatari and Yokota, Appl Environ Microbiol (2007) 73(12) pp 3909-3915] 참조); 이와 같이, 치료용 박테리아가 유산균, 예컨대 락토바실러스 종인 경우, 선택적 저해는 pH를 8.0 이상으로 상승시킴으로써 달성될 수 있다.
다른 치료용 박테리아에 대한 최적의 성장 조건도 또한 당업계에 알려져 있다. 예를 들어, 블라우티아 하이드로게노트로피카(Blautia hydrogenotrophica)에 대한 최적 성장 조건은 6.0 내지 7.0의 pH 범위, 및 35 내지 37℃의 온도이다.　문헌[Bernalier et al. Archives of Microbiology, 1996. Volume 166(3). p. 176-83] 및 따라서 본 발명의 방법은 6.0 미만 또는 7.0 초과의 pH 및/또는 35℃ 미만 또는 37℃ 미만의 온도를 사용하여 실시될 수 있다.
저해제
대안적으로, 또는 추가적으로, 선택적 저해는 치료용 박테리아의 성장을 선택적으로 저해하는 작용제 또는 작용제들을 배양 배지에 첨가함으로써 달성될 수 있다. 작용제는 치료용 박테리아가 증식하는 것을 방지할 수 있거나, 예를 들어 적어도 80%, 85%, 90%, 95% 96%, 97%, 98%, 99%, 99.5% 또는 99.9%만큼 증식을 감소시킬 수 있다. 바람직하게는, 작용제는 치료용 박테리아를 적어도 90%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.9% 또는 (가장 바람직하게는) 100% 능동적으로 살해한다. 이러한 작용제의 예는 박테리오파지(보통 "파지"로 알려짐), 라이소자임 및 항생제를 포함한다.
치료용 박테리아에 특이적이고, 따라서 임의의 원치 않는 유기체가 또한 박테리아일지라도 이의 성장을 저해할 파지를 선택하는 것이 가능하기 때문에 파지의 사용은 특히 바람직하다. 특정 파지(들)가 사용되면, 치료용 박테리아는 살해될 것이고 원치 않는 유기체는 성장할 수 있을 것이다. 실시예에 제시된 데이터는 고농도의 치료용 박테리아를 신속하게 불활성화시키는 파지의 능력을 입증하여, 따라서 임의의 원치 않는 유기체(상기 실시예에서는, 박테리아 유기체)의 편리하고 직접적인 식별을 용이하게 한다. 라이소자임과 비교하여 파지의 사용은 라이소자임을 단리하고 정제하는 추가적인 공정을 피하므로, 파지의 사용은 또한 유리하다.
일 실시형태에서, 작용제는 LysA2가 아니거나, 단리된 파지 용해 효소가 아니거나, 재조합 파지 용해 효소가 아니다. 파지 용해 효소가 박테리아에서 용해를 유도할 수 있는 박테리오파지로부터 유래된 임의의 효소임이 이해될 것이다. 일 실시형태에서, 작용제는 단리된 파지 효소 또는 단백질이 아니다. 일 실시형태에서, 작용제는 재조합 파지 효소 또는 단백질이 아니다. 일 실시형태에서, 선택적 저해는 단리된 및/또는 재조합 파지 용해 효소를 배양 배지에 첨가함으로써 달성되지 않는다.
본 발명의 방법에서 사용하기에 적합한 파지는 자연적으로 발생하는 파지, 예를 들어 게놈이 공개적으로 이용 가능한(예를 들어, https://www.ebi.ac.uk/ena/browser/home에서 접근 가능한 유럽 뉴클레오타이드 아카이브(European Nucleotide Archive; ENA) 데이터베이스를 통함; 또는 https://www.ncbi.nlm.nih.gov/genomes/GenomesGroup.cgi에서 접근 가능한 NCBI GenBank를 통함) 임의의 파지를 포함한다. 파지는 자연적으로 발생하는 파지 또는 비-자연적으로 발생하는 파지, 예를 들어 유전자 조작되거나 유전자 변형된 파지일 수 있다. 알려진 파지는 미생물-파지 데이터베이스를 사용함으로써 식별될 수 있다(예를 들어, 문헌["MVP: a microbe-phage interaction database", Gao et al., Nucleic Acids Res (2018) 46 (Database Issue): D700-D707; http://mvp.medgenius.info/home에서 접근 가능함; 또는 https://www.genome.jp/virushostdb/에서 접근 가능한 바이러스-숙주 데이터베이스]). 파지의 특이성은 임의의 알려진 기법을 사용하여 결정될 수 있으며(예를 들어, 문헌["More Is Better: Selecting for Broad Host Range Bacteriophages", Ross et al., Front Microbiol (2016) 7: 1352] 참조); 예를 들어, 파지가 숙주 박테리아의 특정 종 또는 균주에 플라크를 형성할 수 있는지 여부를 관찰하거나, 박테리아가 파지에 민감한지를 보다 신속하게 결정하기 위한 스팟 테스트를 사용할 수 있다. Ross외 다수는 또한 자연 환경으로부터 파지를 단리하기 위한 기법을 설명한다.
파지는 야생형 균주와 비교하여 박테리아의 특정 균주에 더 특이적이도록 유전자 조작될 수 있거나, 특정 종의 임의의 균주를 감염시킬 수 있도록 야생형 균주와 비교하여 덜 선택적이 되도록 조작될 수 있다. 파지를 유전자 변형하고 조작하기 위한 기법이 당업계에 알려져 있다(예를 들어, 문헌["Engineering Bacteriophages as Versatile Biologics", Kilcher and Loessner, Trends in Microbiology (2019) 27(4) pp 355-367; "Approaches to optimize therapeutic bacteriophage and bacteriophage-derived products to combat bacterial infections", Reuter and Kruger, Virus Genes (2020) 56(2) pp 136-149; "Creation of synthetic bacterial viruses", Ando, Nihon Saikingaku Zasshi (2018) 73(4) pp 201-210; "Phage Therapy in the Era of Synthetic Biology", Barbu et al., Cold Spring Harb Perspect Biol (2016) 8(10):a023879; "Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins", Dunne et al., Cell Reports (2019) 29(5) pp 1336-1350] 참조). 합성 게놈 조립체 및 바이러스 게놈 조작은 원하는 특성, 예를 들어 더 높거나 더 낮은 특이성을 갖는 파지를 형성하는 데 사용될 수 있다.
본 발명의 바람직한 실시형태에서, 복수의 파지가 치료용 박테리아의 선택적 저해를 달성하는 데 이용될 수 있으며, 예를 들어 2, 3, 4, 5, 6, 7, 8, 9, 10가지 또는 10가지 초과의 파지가 이용될 수 있다. 이들 파지는 동일한 치료용 박테리아(예를 들어, 동일한 박테리아 균주 또는 종)에 특이적일 수 있거나 복수의 치료용 박테리아(예를 들어, 복수의 박테리아 종)에 특이적일 수 있다. 후자의 실시형태는 본 발명이 박테리아 컨소시엄(consortia)을 포함하는 조성물을 테스트하는 데 사용되는 경우에 특히 유용하다. 본 발명은 또한 선택적으로 안정화제, 방부제 및/또는 첨가제와 함께 이러한 파지를 포함하는 조성물을 제공한다.
본 발명과 함께 사용될 수 있는 파지의 예는 다음을 포함한다: ΦCrAss001(박테로이데스 박테리아에 특이적), B124-14(박테로이데스 박테리아에 특이적), B40-8(박테로이데스 박테리아에 특이적), AUEF3(엔테로코커스 박테리아에 특이적), BC611(엔테로코커스 박테리아에 특이적), Ec-ZZ2(엔테로코커스 박테리아에 특이적), A2(락토바실러스(Lactobacillus) 박테리아에 특이적), 521B(락토바실러스 박테리아에 특이적), c2(락토바실러스 박테리아에 특이적), 또는 phiCDHM11(클로스트리듐 박테리아에 특이적).
파지는 그람 양성 박테리아, 예를 들어 엔테로코커스 속의 박테리아에 특이적일 수 있다. 파지는 DNA 게놈을 가질 수 있다. 파지는 장내구균 박테리아에 특이적일 수 있으며, 선택적으로 비-장내구균 박테리아를 감염시킬 수 없다. 파지는 단지 장내구균 박테리아의 성장을 선택적으로 저해할 수 있다. 엔테로코커스-특이적 파지는 본 발명의 방법에 상당한 가치가 있는데, 이는 본 발명자들이 아는 한, 본 발명의 방법에서 사용되기에 충분한 특이성 및 효능을 갖는 파지가 이전에 알려지지 않았으며, 어떠한 엔테로코커스-특이적 항생제도 이용 가능하지 않았기 때문이다.
바람직하게는, 파지는 치료용 박테리아에 대해 높은 특이성 및 높은 선택성을 갖는다. 일 실시형태에서, 파지(들)는 10가지 이하의 상이한 박테리아 종, 예컨대, 9, 8, 7, 6, 5, 4, 3, 2, 또는 1가지 이하의 박테리아 종의 성장을 저해하며, 바람직하게는 상이한 종 각각은 동일한 속에 속한다. 일 실시형태에서, 파지(들)는 단지 한 가지 박테리아 종의 성장을 저해한다. 일 실시형태에서, 파지(들)는 10가지 이하의 상이한 박테리아 균주, 예컨대, 9, 8, 7, 6, 5, 4, 3, 2, 또는 1가지 이하의 박테리아 균주의 성장을 저해하며, 바람직하게는 상이한 균주 각각은 동일한 종에 속한다. 일 실시형태에서, 파지(들)는 단지 한 가지 박테리아 균주의 성장을 저해한다. 일 실시형태에서, 파지(들)는 알려진 특이성 및/또는 알려진 선택성을 갖는다.
일 실시형태에서, 파지(들)는 조성물 중 치료용 박테리아의 성장을 선택적으로 저해한다. 일 실시형태에서, 파지(들)는 치료용 박테리아, 및 치료용 박테리아와 동일한 종의 임의의 박테리아의 성장을 선택적으로 저해한다. 일 실시형태에서, 파지(들)는 조성물 중 단지 치료용 박테리아의 성장을 저해한다. 일 실시형태에서, 파지(들)는 조성물 중 임의의 원치 않는 유기체의 성장을 저해하지 않는다.
치료용 박테리아가 장내구균 박테리아인 경우, 특히 적합한 파지는 NCIMB 43666 파지 및 NCIMB 43667 파지(둘 다 4D Pharma Research Ltd.(AB25 2ZS, 애버딘, 콘힐 로드, 라이프 사이언스 및 이노베이션 빌딩 소재)에 의해 NCIMB Ltd.(스코틀랜드 AB21 9YA, 애버딘, 벅스번, 크레이브스톤 에스테이트, 페르구손 빌딩 소재)에 기탁됨)를 포함하며, 이들 둘 다 장내구균 박테리아, 특히 엔테로코커스 갈리나룸, 예컨대, 엔테로코커스 갈리나룸 균주 NCIMB 42488(또한 4D Pharma Research Ltd.(AB25 2ZS, 애버딘, 콘힐 로드, 라이프 사이언스 및 이노베이션 빌딩 소재)에 의해 NCIMB Ltd.(스코틀랜드 AB21 9YA, 애버딘, 벅스번, 크레이브스톤 에스테이트, 페르구손 빌딩 소재)에 기탁됨)에 특이적이다. 이들 파지는 엔테로코커스 갈리나룸(구체적으로 엔테로코커스 갈리나룸 균주 NCIMB 42488)에 매우 특이적이며 배지에 존재할 수 있는 다른 원치 않는 미생물에 영향을 미치지 않는 것으로 밝혀졌다. 따라서 이들 파지는 엔테로코커스 갈리나룸, 예컨대, 엔테로코커스 갈리나룸 균주 NCIMB 42488의 성장을 특이적으로 저해하는 데 적합한 작용제이다.
일 실시형태에서, 파지는 단지 엔테로코커스 갈리나룸 종 박테리아의 성장을 선택적으로 저해한다. 일 실시형태에서, 파지는 엔테로코커스 갈리나룸 균주 NCIMB 42488 박테리아의 성장을 선택적으로 저해한다. 일 실시형태에서, 파지는 단지 엔테로코커스 갈리나룸 박테리아의 성장을 저해한다. 일 실시형태에서, 파지는 단지 엔테로코커스 갈리나룸 균주 NCIMB 42488 박테리아의 성장을 저해한다.
따라서, 바람직하게는 치료용 박테리아가 엔테로코커스 속의 박테리아를 포함하거나 이로 이루어지는 경우, NCIMB 43667 파지가 본 발명에서 사용하기에 바람직하다. 바람직하게는, 이 파지는 치료용 박테리아가 엔테로코커스 갈리나룸 종, 가장 바람직하게는 엔테로코커스 갈리나룸 균주 NCIMB 42488의 박테리아를 포함하거나 이로 이루어지는 경우 사용된다. NCIMB 43667의 게놈에 대한 핵산 서열은 서열번호 1에 제시되어 있다. 서열번호 3 내지 68 각각은 NCIMB 43667 게놈의 개별 노드를 나타내며, 여기서 각각의 노드는 파지 게놈의 서열결정 동안 조립된 스캐폴드 또는 콘티그(contig)이다. 길이가 1000개 염기쌍을 초과하는 임의의 노드는 적어도 파지 게놈의 실제 부분을 나타낼 가능성이 있다. 따라서 일 실시형태에서, NCIMB 43667 게놈의 핵산 서열은 임의의 순서로 서열번호 3 내지 8 중 적어도 1개, 적어도 2개, 적어도 3개, 적어도 4개, 적어도 5개 또는 전부를 포함한다. NCIMB 43667 및 하기 기재된 분석에서 동일하거나 유사한 활성을 갖는 이의 임의의 변이체는 또한 본 발명의 일부이다. 이 파지의 추가 상세내용은 하기 실시예에 개시되어 있다. NCIMB 43667 파지의 변이체는 서열번호 1과 적어도 70%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 동일한 DNA 게놈을 가질 수 있다. NCIMB 43667 파지의 변이체는 서열번호 3 내지 8 또는 3 내지 68과 적어도 70%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 동일한 DNA 게놈을 가질 수 있다. 본 발명의 방법은 또한 NCIMB 43667 파지와 기능적으로 동등한 파지를 사용하여 실시될 수 있다(이러한 기능적으로 동등한 파지는 앞 문장에 정의된 바와 같은 서열번호 1과 서열 동일성을 갖는 DNA 게놈을 가질 수 있음). "기능적으로 동등한"은 파지가 엔테로코커스 갈리나룸 균주 NCIMB 42488의 성장을 NCIMB 43667 파지와 비교하여 동일한 정도로, 또는 적어도 90%, 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 저해할 수 있음을 의미한다. 성장 저해는 NCIMB 43667 및 관심이 있는 파지의 성장 저해가 동시에 측정되고 비교되는 파일럿 실험에서 쉽게 결정될 수 있다. 성장 저해는 한천에서 파지와 엔테로코커스 갈리나룸 균주 NCIMB 42488의 혼합물을 도말하고 생성된 박테리아 론(bacterial lawn)에서 플라크 형성을 검사함으로써 측정될 수 있다(예를 들어, 100㎕의 미리 결정된 파지 희석액을 500㎕의 엔테로코커스 갈리나룸 균주 NCIMB 42488 배양액과 조합하고, 42℃에서 3㎖ 상단 한천에 첨가한 다음, 카제인 펩톤 대두 펩톤(CASO) 한천 상에 분배하고, 플라크 형성 검사 이전에 37℃에서 16 내지 48시간 동안 인큐베이션함). 그 다음 플라크의 수 또는 플라크 형성 단위는, 예를 들어 성장 저해를 나타내는 데 사용될 수 있다.
NCIMB 43666 파지는 또한 본 발명에서 사용하기에 바람직하다. 이 파지는 치료용 박테리아가 엔테로코커스 속의 박테리아를 포함하거나 이로 이루어지는 경우 특히 유용하다. 바람직하게는, 이 파지는 치료용 박테리아가 엔테로코커스 갈리나룸 종, 가장 바람직하게는 엔테로코커스 갈리나룸 균주 NCIMB 42488의 박테리아를 포함하거나 이로 이루어지는 경우 사용된다. NCIMB 43666의 게놈에 대한 핵산 서열은 서열번호 2에 제시되어 있다. 서열번호 69 내지 2626 각각은 게놈의 개별 노드를 나타내며, 여기서 각각의 노드는 파지 게놈의 서열결정 동안 조립된 스캐폴드 또는 콘티그이다. 길이가 1000개 염기쌍을 초과하는 임의의 노드는 적어도 파지 게놈의 실제 부분을 나타낼 가능성이 있다. 따라서 일 실시형태에서, NCIMB 43667 게놈의 핵산 서열은 임의의 순서로 서열번호 69 내지 74 중 적어도 1개, 적어도 2개, 적어도 3개, 적어도 4개, 적어도 5개 또는 전부를 포함한다. NCIMB 43666 및 하기 기재된 분석에서 동일하거나 유사한 활성을 갖는 이의 임의의 변이체는 또한 본 발명의 일부이다. 이 파지의 추가 상세내용은 하기 실시예에 개시되어 있다. 본 발명에 따른 NCIMB 43666 파지의 변이체는 서열번호 2와 적어도 70%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 동일한 DNA 게놈을 가질 수 있다. 본 발명에 따른 NCIMB 43666 파지의 변이체는 서열번호 69 내지 74 중 적어도 1개, 적어도 2개, 적어도 3개, 적어도 4개, 또는 적어도 5개 또는 전부, 또는 서열번호 69 내지 2626 중 1개 또는 일부 또는 전부와 적어도 70%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 동일한 DNA 게놈을 가질 수 있다.본 발명의 방법은 또한 NCIMB 43666 파지와 기능적으로 동등한 파지를 사용하여 실시될 수 있다(이러한 기능적으로 동등한 파지는 앞 문장에 정의된 바와 같은 서열번호 2와 서열 동일성을 갖는 DNA 게놈을 가질 수 있음). "기능적으로 동등한"은 파지가 엔테로코커스 갈리나룸 균주 NCIMB 42488의 성장을 NCIMB 43666과 비교하여 동일한 정도로, 또는 적어도 90%, 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 저해할 수 있음을 의미한다. 성장 저해는 NCIMB 43666 및 관심이 있는 파지의 성장 저해가 동시에 측정되고 비교되는 파일럿 실험에서 쉽게 결정될 수 있다. 성장 저해는 한천에서 파지와 엔테로코커스 갈리나룸 균주 NCIMB 42488의 혼합물을 도말하고 생성된 박테리아 론에서 플라크 형성을 검사함으로써 측정될 수 있다(예를 들어, 100㎕의 미리 결정된 파지 희석액을 500㎕의 엔테로코커스 갈리나룸 균주 NCIMB 4248 배양액과 조합하고, 42℃에서 3㎖ 상단 한천에 첨가한 다음, 카제인 펩톤 대두 펩톤(CASO) 한천 상에 분배하고, 플라크 형성 검사 이전에 37℃에서 16 내지 48시간 동안 인큐베이션함). 그 다음 플라크의 수 또는 플라크 형성 단위는, 예를 들어 성장 저해를 나타내는 데 사용될 수 있다.
2개 뉴클레오타이드 서열 간의 서열 동일성 백분율에 대한 언급은 정렬될 때 2개 서열을 비교할 때 동일한 뉴클레오타이드의 백분율을 지칭한다. 이러한 정렬 및 상동성 또는 서열 동일성 백분율은 당업계에 알려진 소프트웨어 프로그램, 예를 들어 문헌[ref. Current Protocols in Molecular Biology (F.M. Ausubel et al., eds., 1987) Supplement 30]의 섹션 7.7.18, ["Review of Common Sequence Alignment Methods: Clues to Enhance Reliability", Current Genomics (Lambert et al., 2003); "Multiple sequence alignment modeling: methods and applications", Briefings in Bioinformatics (Chatzou et al., 2016); 또는 Statistics for Bioinformatics: Methods for Multiple Sequence Alignment (Thompson, 2017, ISTE Press 발행 - Elsevier)]에 기재된 것을 사용하여 결정될 수 있다. 서열 정렬은 국소적 또는 전면적일 수 있고, 바람직하게는 전면적이다. 바람직한 국소적 정렬은 12개의 갭 개방 페널티 및 2의 갭 확장 페널티, BLOSUM62 매트릭스를 갖는 아핀(affine) 갭을 사용하는 Smith-Waterman 상동성 검색 알고리즘에 의해 결정된다. Smith-Waterman 상동성 검색 알고리즘은 문헌[Smith & Waterman (1981) Adv. Appl. Math. 2: 482-489]에 개시되어 있다. 국소 정렬은 또한 BLOSUM50 매트릭스를 사용하여 Smith-Waterman 상동성 검색 알고리즘에 의해 달성될 수 있다. 바람직한 전면적 정렬은 문헌[Needleman & Wunsch (1970) Journal of Molecular Biology, 48(3):443-453]에 개시된 Needleman-Wunsch 알고리즘에 의해 결정된다.
특히 치료용 박테리아가 엔테로코커스 속의 박테리아를 포함하거나 이로 이루어지는 경우 NCIMB 43667과 NCIMB 43666 파지의 조합(또는 상기 정의된 바와 같은 이의 변이체 및/또는 기능적 등가물)은 본 발명에서 사용하기에 특히 바람직한데, 이는 본 발명자들이 이들 파지의 조합으로 특히 양호한 결과를 보았기 때문이다. 바람직하게는, 이 파지의 조합은 치료용 박테리아가 엔테로코커스 갈리나룸 종, 가장 바람직하게는 엔테로코커스 갈리나룸 균주 NCIMB 42488의 박테리아를 포함하거나 이로 이루어지는 경우 사용된다.
원치 않는 유기체가 박테리아인 본 발명의 실시형태에서, 작용제로서 파지를 사용하는 것이 특히 바람직하다. 실시예에 제시된 데이터는 고농도의 치료용 박테리아를 신속하게 불활성화시키는 파지의 능력을 입증하여, 따라서 임의의 원치 않는 유기체(상기 실시예에서는, 박테리아 유기체)의 편리하고 직접적인 식별을 용이하게 한다. 라이소자임과 비교하여 파지의 사용은 라이소자임을 단리하고 정제하는 추가적인 공정을 피하므로, 파지의 사용은 또한 유리하다.
대안적으로, 또는 추가적으로, 본 발명의 방법은 라이소자임을 사용하여 실시될 수 있다. 또한 무라미다제 또는 N-아세틸무라마이드글리칸하이드롤라제로 알려진 라이소자임은 선천적 면역계의 일부를 형성하는 동물에 의해 생성되는 항균 효소이다. 라이소자임은, 그람-양성 박테리아 세포벽의 주요 구성요소인 펩타이도글리칸에서 N-아세틸무라민산 및 N-아세틸-D-글루코사민 잔기 사이 1,4-베타-연결의 가수분해를 촉매하는 글리코사이드 가수분해효소이다. 이러한 가수분해는 결국 박테리아 세포벽의 무결성을 손상시켜 박테리아의 용해를 유발한다.
본 발명에서 이용될 수 있는 특정 라이소자임은 알려진 라이소자임 중 임의의 것으로부터 선택될 수 있고 치료용 박테리아가 그람-양성 박테리아이고 하나 이상의 원치 않는 유기체가 그람-양성 박테리아가 아닌 경우에 특히 유용하다. 라이소자임은 자연적으로 발생하거나 비-자연적으로 발생할 수 있다. 예를 들어, 라이소자임은 조작되어, 예를 들어 치료용 박테리아에 대한 특이성을 증가시켰을 수 있다. 라이소자입은 c-유형 라이소자임(닭-유형 또는 종래-유형), g-유형 라이소자임(거위-유형), 또는 i-유형 라이소자임(무척추동물 유형)일 수 있다. 다수 라이소자임이 사용될 수 있으며, 예를 들어 암탉 라이소자임과 인간 라이소자임의 조합이 사용될 수 있다. 비-자연적으로 발생하는 라이소자임, 예를 들어 인공적으로 돌연변이된 라이소자임, 재조합 라이소자임, 또는 라이소자임 융합 단백질이 또한 사용될 수 있다.
항생제
본 발명은 또한 항생제를 사용하여 실시될 수 있다. 이러한 실시형태는 원치 않는 유기체가 박테리아가 아니지만, 예를 들어 바이러스인 경우에 특히 적합하다.
항생제는 일반적으로 이의 작용 메커니즘, 화학 구조, 또는 활성 범위에 기반하여 분류된다. 대부분은 박테리아 기능 또는 성장 과정을 표적으로 한다. 항생제는 살균제 또는 정균제일 수 있다. 박테리아 세포벽을 표적으로 하는 것(페니실린 및 세팔로스포린) 또는 세포막을 표적으로 하는 것(폴리믹신) 또는 필수적인 박테리아 효소를 방해하는 것(리파마이신, 리피아르마이신, 퀴놀론 및 설폰아마이드)은 살균 활성을 갖는다. 단백질 합성 저해제(마크롤라이드, 린코사마이드 및 테트라사이클린)는 보통 정균제(살균성 아미노글리코사이드를 제외함)이다. 추가 분류는 이의 표적 특이성에 기반한다. "협범위" 항생제는 특정 유형의 박테리아, 예컨대, 그람-음성 또는 그람-양성을 표적으로 하는 반면, 광범위 항생제는 광범위한 박테리아에 영향을 미친다.
본 발명에서 사용될 수 있는 특정 항생제는 저해될 필요가 있는 치료용 박테리아 및 성장하도록 허용될 하나 이상의 원치 않는 유기체에 기반하여 쉽게 선택될 수 있다. 항생제는 살균제 또는 정균제일 수 있다. 항생제는 자연적으로 발생하는 항생제, 합성 항생제, 또는 반합성 항생제일 수 있다.
항생제는 원치 않는 유기체가 영향을 받지 않음을 보장하기 위하여 바람직하게는 협범위 항생제이다. 협범위 항생제의 적합한 예는 주로 그람-양성 박테리아에 대해 효과적인 페니실린 G, 또한 주로 그람-양성 박테리아, 특히 포도상구균(staphylococcal) 박테리아에 대해 효과적인 반코마이신 및 마크롤라이드, 주로 그람-음성 박테리아에 대해 효과적인 테모실린을 포함한다. 그람-음성 박테리아에 특이적인 항생제는 치료용 박테리아가 그람-음성이고 하나 이상의 원치 않는 유기체가 그람-음성 박테리아가 아닌 경우에 바람직하게 사용된다. 그람-양성 박테리아에 특이적인 항생제는 치료용 박테리아가 그람-양성이고 하나 이상의 원치 않는 유기체가 그람-양성 박테리아가 아닌 경우에 바람직하게 사용된다. 예를 들어, 치료용 박테리아가 장내구균 박테리아인 경우, 그람-양성 박테리아에 특이적인 협범위 항생제가 바람직하게 사용된다.
대안적으로, 일 실시형태에서, 치료용 박테리아의 성장은 치료용 박테리아의 성장을 저해하는 작용제를 배양 배지에 첨가함으로써 선택적으로 저해되며, 단 작용제는 항생제가 아니다. 일 실시형태에서, 작용제는 반코마이신이 아니다. 일 실시형태에서, 작용제는 소듐 포스페이트 또는 글리세로포스페이트가 아니다.
일 실시형태에서, 선택적 저해는 항생제의 첨가에 의해 달성되지 않는다.
조합
본 발명은 또한 이전 단락에서 논의된 저해 방법의 조합을 사용하여 실시될 수 있다. 동일하거나 상이한 저해 방법이 이용될 수 있다. 예를 들어, 본 발명에 따른 방법은 라이소자임의 존재 하에 낮은 pH에서 미생물 조성물을 성장시키는 단계를 포함할 수 있다. 대안적으로, 본 발명의 방법은 2가지 유형의 파지의 존재 하에 미생물 조성물을 성장시키는 단계를 포함할 수 있다.
조성물
본 발명에 따른 미생물 조성물은 가장 바람직하게는 LBP이다. 일부 실시형태에서, 상기 미생물 조성물은 백신일 수 있다.
바람직한 실시형태에서, 미생물 조성물은 본 발명 방법의 단계 (a) 전에 약제학적으로 허용 가능하다. 가장 바람직하게는, 오염 박테리아 및/또는 바이러스가 미생물 조성물에 첨가되지 않는다.
본 발명의 실시형태에서, 미생물 조성물은 최종 완제 의약품 조성물 또는 단위 용량(예를 들어, 단일 정제 또는 캡슐)이다. 예를 들어, 미생물 조성물은 치료용 박테리아에 추가적으로 부형제, 예컨대, 동결보호제, 방부제, 항산화제, 안정화제, 프리바이오틱 화합물, 약제학적으로 허용 가능한 담체 또는 희석제, 결합제, 윤활제, 현탁화제, 코팅제, 가용화제 등을 포함할 수 있다. 추가적으로 또는 대안적으로, 미생물 조성물은 1×1010 CFU 이하, 1011 이하의 치료용 박테리아를 포함할 수 있다. 실시예에서 입증된 바와 같이, 본 발명의 방법은 단일 투약 형태에서 원치 않는 박테리아의 존재 또는 부재가 결정될 수 있을 만큼 충분히 민감하다. 또한, 본 발명의 방법은 미생물 순도 평가를 개시하기 이전에 부형제로부터 치료용 박테리아를 분리할 필요가 없다. 단일 투약 형태는 장용 제형, 즉, 경구 투여에 의해 장으로 조성물을 전달하기에 적합한 위-내성 제형(예를 들어, 위 pH에 대해 내성)일 수 있다. 단일 투약 형태는 장용 코팅을 포함할 수 있다.
미생물 조성물은 벌크(bulk)로부터 취해진 샘플일 수 있다. 그 다음 샘플은 본 발명에 따라 분석될 수 있다. 결과가 원치 않는 유기체의 부재를 나타낸다면, 벌크는 추가로 처리되어, 예를 들어 단위 용량의 약제를 제조할 수 있다.
미생물 조성물이 백신인 경우, 치료용 박테리아는 병원성 박테리아, 또는 선택적으로 병원성 박테리아의 비-독성 균주일 수 있다. 따라서 백신 미생물 조성물 중 치료용 박테리아는 또한 최종 완제 의약품 조성물 또는 단위 용량에서 살아있을 수 있다. 일 실시형태에서, 백신 미생물 조성물은 약독화된 치료용 박테리아를 포함하지 않는다. 대안적으로 또는 추가적으로, 살아있는 비-병원성 박테리아를 이용한 접종은 하나 이상의 병원성 박테리아에 대해 환자를 면역화하기 위해, 치료용 박테리아는 하나 이상의 병원성 박테리아 유래의 하나 이상의 항원을 포함하는 유전자 조작된 비-병원성 박테리아일 수 있다. 일 실시형태에서, 유전자 조작된 비-병원성 박테리아는 하나 이상의 병원성 박테리아 유래의 하나 이상의 항원을 발현한다. 일 실시형태에서, 유전자 조작된 비-병원성 박테리아는 하나 이상의 병원성 박테리아 유래의 하나 이상의 항원을 인코딩하는 핵산을 포함하는 하나 이상의 플라스미드를 포함한다.
일 실시형태에서, 본 발명의 방법은 치료용 박테리아 또는 치료용 박테리아들의 성장을 선택적으로 저해하는 조건 하에서 치료용 박테리아를 포함하는 미생물 조성물을 배양하는 단계 이전에 미생물 조성물을 제조하되, 미생물 조성물은 환자, 선택적으로 인간 환자에게 투여하기에 적합한 최종 완제 의약품 조성물인 단계, 및 임의의 원치 않는 유기체가 미생물 조성물에 존재하는지 여부를 결정하기 위해 배양된 미생물 조성물을 분석하는 단계를 포함한다.
조성물은 치료용 박테리아의 하나 초과의 종 또는 균주를 포함할 수 있다. 박테리아가 다수의 균주를 포함하는 경우, 이는 상이한 문, 강, 목, 과, 속, 또는 종에 속할 수 있거나, 동일한 종의 상이한 균주일 수 있다. 예를 들어, 다수의 치료용 박테리아 균주는 동일한 문이지만 상이한 강의 것일 수 있거나; 동일한 강이지만 상이한 목의 것일 수 있거나; 상이한 목이지만 상이한 과의 것일 수 있거나; 상이한 과이지만 상이한 속의 것일 수 있거나; 동일한 속이지만 상이한 종의 것일 수 있거나; 동일한 종이지만 상이한 균주의 것일 수 있다. 이들 범주의 조합을 포함하는 미생물 조성물은 또한 본 발명에 포함되며, 예를 들어 치료용 박테리아는 동일한 속이지만 상이한 종의 2가지 이상의 치료용 박테리아 균주 및 동일한 종이지만 상이한 균주의 2가지 이상의 치료용 박테리아 균주를 포함할 수 있다. 미생물 조성물은 박테로이데테스 문 및 피르미큐테스 문, 또는 둘 다의 다수의 상이한 치료용 박테리아 균주를 포함할 수 있다. 미생물 조성물은 엔테로코커스 속의 치료용 박테리아의 다수 종을 포함할 수 있다. 미생물 조성물은 엔테로코커스 갈리나룸 종의 치료용 박테리아의 다수 균주를 포함할 수 있다. 일 실시형태에서, 미생물 조성물은 엘. 젠세니를 포함하지 않는다. 일 실시형태에서, 치료용 박테리아는 엘. 젠세니를 포함하지 않는다.
미생물 조성물은 단일 치료용 박테리아 균주를 포함할 수 있다. 대안적으로, 미생물 조성물은 치료용 박테리아 균주의 컨소시엄을 포함할 수 있으며, 예를 들어 미생물 조성물은 복수의 치료용 박테리아 균주를 포함할 수 있다. 예를 들어, 일부 실시형태에서, 미생물 조성물은 동일한 종 내 하나 초과의 균주(예를 들어, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 25, 30, 35, 40 또는 45가지 초과의 균주)를 포함할 수 있으며, 선택적으로 임의의 다른 종의 치료용 박테리아를 포함하지 않는다. 일부 실시형태에서, 치료용 박테리아는 동일한 종 내 50가지 미만의 균주(예를 들어, 45, 40, 35, 30, 25, 24, 23, 22, 21, 20, 19, 18, 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4 또는 3가지 미만의 균주)를 포함할 수 있으며, 선택적으로 임의의 다른 종의 치료용 박테리아를 포함하지 않는다. 일부 실시형태에서, 미생물 조성물은 동일한 종 내 1 내지 40, 1 내지 30, 1 내지 20, 1 내지 19, 1 내지 18, 1 내지 171 내지 15, 1 내지 10, 1 내지 9, 1 내지 8, 1 내지 7, 1 내지 6, 1 내지 5, 1 내지 4, 1 내지 3, 1 내지 2, 2 내지 50, 2 내지 40, 2 내지 30, 2 내지 20, 2 내지 15, 2 내지 10, 2 내지 5, 6 내지 30, 6 내지 15, 16 내지 25 또는 31 내지 50가지 균주를 포함하며, 선택적으로 임의의 다른 종의 치료용 박테리아를 포함하지 않는다.
일부 실시형태에서, 미생물 조성물은 하나 초과의 종(예를 들어, 동일한 속 내 하나 초과의 종), 예를 들어 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 30, 35 또는 40가지 종의 치료용 박테리아 균주를 포함하며, 선택적으로 임의의 다른 종의 치료용 박테리아 균주를 포함하지 않는다. 일부 실시형태에서, 미생물 조성물은 50가지 미만의 종(예를 들어, 동일한 속 내 50가지 미만의 종), 예를 들어 50, 45, 40, 35, 30, 25, 20, 19, 18, 17, 16, 15, 12, 10, 8, 7, 6, 5, 4 또는 3가지 미만의 종의 치료용 박테리아 균주를 포함하며, 선택적으로 임의의 다른 속의 치료용 박테리아를 포함하지 않는다. 일부 실시형태에서, 치료용 박테리아는 동일한 속 내 1 내지 50, 1 내지 40, 1 내지 30, 1 내지 20, 1 내지 19, 1 내지 18, 1 내지 17, 1 내지 16, 1 내지 15, 1 내지 10, 1 내지 9, 1 내지 8, 1 내지 7, 1 내지 6, 1 내지 5, 1 내지 4, 1 내지 3, 1 내지 2, 2 내지 50, 2 내지 40, 2 내지 30, 2 내지 20, 2 내지 15, 2 내지 14, 2 내지 13, 2 내지 12, 2 내지 11, 2 내지 10, 2 내지 5, 6 내지 30, 6 내지 15, 16 내지 25, 또는 31 내지 50가지 종의 균주를 포함하며, 선택적으로 임의의 다른 속의 치료용 박테리아를 포함하지 않는다. 미생물 조성물은 상기한 것의 임의의 조합을 포함할 수 있다. 일부 실시형태에서, 미생물 조성물은 치료용 박테리아 균주의 컨소시엄을 포함한다. 일부 실시형태에서, 치료용 박테리아 균주의 컨소시엄은 단일 유기체, 예를 들어 인간의 배설물 샘플로부터 수득한 2가지 이상의 치료용 박테리아 균주를 포함한다. 일부 실시형태에서, 치료용 박테리아 균주의 컨소시엄은 자연에서 함께 발견되지 않는다. 예를 들어, 일부 실시형태에서, 치료용 박테리아 균주의 컨소시엄은 적어도 2가지 상이한 유기체의 배설물 샘플로부터 수득된 치료용 박테리아 균주를 포함한다. 일부 실시형태에서, 2가지 상이한 유기체는 동일한 종 유래이며, 예를 들어 2명의 상이한 인간이다. 일부 실시형태에서, 2가지 상이한 유기체는 유아 인간 및 성인 인간이다. 일부 실시형태에서, 2가지 상이한 유기체는 인간 및 비-인간 포유동물이다.
치료용 박테리아는 혐기성 박테리아, 편성 혐기성 박테리아, 통성 혐기성 박테리아 및/또는 미호기성 박테리아를 포함하거나 이로 이루어질 수 있다.
치료용 박테리아는 다음 속 유래의 박테리아를 포함하거나 이로 이루어질 수 있다: 엔테로코커스(예를 들어, 엔테로코커스 갈리나룸, 엔테로코쿠스 카셀리플라버스(Enterococcus caselliflavus), 엔테로코쿠스 페칼리스(Enterococcus faecalis) 또는 엔테로코쿠스 페시움(Enterococcus faecium)), 블라우티아(예를 들어, 블라우티아 하이드로게노트로피카, 블라우티아 스테르코리스(Blautia stercoris), 블라우티아 웩슬러레(Blautia wexlerae) 또는 블라우티아 프로덕타(Blautia producta)), 박테로이데스(예를 들어, 박테로이데스 테타이오타오미크론(Bacteroides thetaiotaomicron), 박테로이데스 마실리엔시스(Bacteroides massiliensis), 박테로이데스 프라질리스(Bacteroides fragilis), 박테로이데스 오바투스(Bacteroides ovatus), 박테로이데스 불가투스(Bacteroides vulgatus), 박테로이데스 도레이(Bacteroides dorei) 또는 박테로이데스 코프리콜라(Bacteroides copricola)), 페칼리박테리움(Faecalibacterium)(예를 들어, 페칼리박테리움 프라우스니치(Faecalibacterium prausnitzii)), 바리아트리쿠스(Bariatricus)(예를 들어, 바리아트리쿠스 마실리엔시스(Bariatricus massiliensis)), 비피도박테리움(예를 들어, 비피도박테리움 브레베(Bifidobacterium breve), 비피도박테리움 아돌레센티스(Bifidobacterium adolescentis) 또는 비피도박테리움 롱검(Bifidobacterium longum)), 로제부리아(Roseburia)(예를 들어, 로제부리아 호미니스, 로제부리아 인테스티날리스(Roseburia intestinalis) 또는 로제부리아 이눌리니보란스(Roseburia inulinivorans)), 플라보니프락토르(Flavonifractor)(예를 들어, 플라보니프락토르 플라우티(Flavonifractor plautii)), 아네로트룬커스(Anaerotruncus)(예를 들어, 아네로트룬커스 콜리호미니스(Anaerotruncus colihominis)), 파라박테로이데스(Parabacteroides)(예를 들어, 파라박테로이데스 디스타소니스(Parabacteroides distasonis), 파라박테로이데스 골드스테이니(Parabacteroides goldsteinii), 파라박테로이데스 메르데(Parabacteroides merdae) 또는 파라박테로이데스 존소니(Parabacteroides johnsonii)), 에리시펠라토클로스트리듐(Erysipelatoclostridium)(예를 들어, 에리시펠라토클로스트리듐 라모섬(Erysipelatoclostridium ramosum)), 메가스페라(Megasphaera)(예를 들어, 메가스페라 마실리엔시스(Megasphaera massiliensis)), 페디오코커스(Pediococcus)(예를 들어, 페디오코커스 악시딜락티시(Pediococcus acidilacticii)), 유박테리움(Eubacterium)(예를 들어, 유박테리움 콘토르텀(Eubacterium contortum), 유박테리움 피시카테나(Eubacterium fissicatena), 유박테리움 엘리젠스(Eubacterium eligens), 유박테리움 하드럼(Eubacterium hadrum), 유박테리움 할리(Eubacterium hallii) 또는 유박테리움 렉타레(Eubacterium rectale)), 루미노코커스(Ruminococcus)(예를 들어, 루미노코커스 토르크(Ruminococcus torques), 루미노코커스 그나버스(Ruminococcus gnavus) 또는 루미노코커스 브로미(Ruminococcus bromii)), 슈도플라보니프락토르(Pseudoflavonifractor)(예를 들어, 슈도플라보니프락토르 카필로서스(Pseudoflavonifractor capillosus)), 클로스트리듐(예를 들어, 클로스트리듐 넥실(Clostridium nexile), 클로스트리듐 힐레모나에(Clostridium hylemonae), 클로스트리듐 부티리쿰(Clostridium butyricum), 클로스트리듐 테르티움(Clostridium tertium), 클로스트리듐 디스포리쿰(Clostridium disporicum), 클로스트리듐 비페르멘탄스(Clostridium bifermentans), 클로스트리듐 이노쿰(Clostridium inocuum), 클로스트리듐 마욤베이(Clostridium mayombei), 클로스트리듐 볼테아에(Clostridium bolteae), 클로스트리듐 바르틀레티(Clostridium bartletti), 클로스트리듐 심비오숨(Clostridium symbiosum) 또는 클로스트리듐 오르비스신덴스(Clostridium orbiscindens)), 코프로코커스(Coprococcus)(예를 들어, 코프로코커스 코메스(Coprococcus comes) 또는 코프로코커스 카투스(Coprococcus cattus)), 아세티비브리오(Acetivibrio)(예를 들어, 아세티비브리오 에타놀기그넨스(Acetovibrio ethanolgignens)), 도레아(Dorea)(예를 들어, 도레아 롱기카테나(Dorea longicatena)) 또는 라크노스피라세(Lachnospiraceae) 과의 임의의 속.
본 발명의 실시형태에서, 미생물 조성물은 락토바실러스 속 및/또는 락토바실라세아에(Lactobacillaceae) 과의 유기체를 포함하지 않는다.
미생물 조성물은 임의의 치료 용도, 예컨대, 암, 위장 질환(예컨대, 염증성 장 질환, 염증성 장 증후군, 크론병), 당뇨병, 치주염, 또는 대사 질환(예컨대, 대사 증후군)의 치료 또는 예방에서의 용도를 가질 수 있다. 예에서, 치료용 박테리아는 암의 치료 또는 예방에서의 치료 용도를 갖는다. 치료용 박테리아는 포유동물, 예를 들어 인간에 대해 병원성 또는 비-병원성일 수 있다. 치료용 박테리아는 자연적으로 발생하는 박테리아 및/또는 인공 박테리아, 예컨대, 유전자 변형된 치료용 박테리아를 포함할 수 있다.
검출
미생물 조성물 중 임의의 원치 않는 유기체는 바람직하게는 배양하는 단계의 초기에 살아 있다.
미생물 조성물에 존재할 수 있는 원치 않는 유기체의 예는 박테리아를 포함한다. 예를 들어, 원치 않는 유기체는 병원성일 수 있는 혐기성 박테리아(예를 들어, 클로스트리디아 또는 살모넬라 속 또는 스타필로코커스 아우레우스, 슈도모나스 아에루기노사 또는 에쉬리키아 콜라이 종으로부터의 병원성 박테리아), 예를 들어 포유동물, 예컨대, 인간에 대해 병원성인 혐기성 박테리아일 수 있다.
임의의 원치 않는 유기체의 식별은 당업자에게 잘 알려진 기법 또는 장치를 사용하여 달성될 수 있다. 예를 들어, 유기체는 다음 기법 중 하나 이상을 사용하여 식별될 수 있다: 미생물 표현형 분석(예컨대, 형태, 그람 염색, 및/또는 항균제에 대한 민감성 식별, 예를 들어 문헌[Chapter 3: "Classification", of Medical Microbiology, 4th edition, 1996, Samuel Baron 편저, 또는 "Methods for the detection and identification of pathogenic bacteria: past, present, and future", Varadi et al., Chem Soc Rev (2017) 46(16) pp 4818-4832] 참조); 질량 분석법(예컨대, MALDI-TOF-MS; 예를 들어, 문헌["Rapid and Robust MALDI-TOF MS Techniques for Microbial Identification: A Brief Overview of Their Diverse Applications", Jang and Kim, J Microbiol (2018) 56(4) pp 209-216] 참조); 핵산 테스트(예컨대, 핵산 서열결정, 및/또는 PCR, 예를 들어 문헌["Routine Ribosomal PCR and DNA Sequencing for Detection and Identification of Bacteria", Kemp et al., Future Microbiol (2010) 5(7) pp 1101-1107] 참조).
특정 실시형태에서, 미생물 조성물 중 원치 않는 유기체 존재의 결정은 배양된 미생물 조성물 중 세포 산물, 바람직하게는 치료용 박테리아에 의해 생산되지 않고/않거나 클로스트리디아 및 살모넬라 속 및 스타필로코커스 아우레우스, 슈도모나스 아에루기노사 및 에쉬리키아 콜라이 종의 병원성 유기체와 같은 특정 병원성 박테리아의 존재를 나타내는 세포 산물의 식별을 포함할 수 있다. 예를 들어, 분석은 대사산물, 예컨대, 단쇄 지방산의 식별을 포함할 수 있다. 추가적으로 또는 대안적으로, 미생물 조성물의 분석은 폴리펩타이드의 식별을 포함할 수 있다.
이러한 화합물의 식별은 당업자에게 친숙한 임의의 기법 또는 장치, 예를 들어 GC-MS 또는 MALDI-TOF-MS 분석의 사용을 통해 달성될 수 있다.
실시형태에서, 방법은 원치 않는 유기체의 허용 불가능한 수준과 원치 않는 유기체의 최소 수준을 구별하기에 충분히 민감하며, 여기서 상기 허용 불가능한 수준은 미리 결정되고, 예를 들어 상기 허용 불가능한 수준은 FDA에 의해 미리 결정될 수 있다. 이 실시형태에서, 예를 들어 사용자가 미생물 조성물 중 원치 않는 유기체(들)의 양이 미리 결정된 안전 규정에 따라 위험한지 여부를 결정할 수 있기 때문에, 유용한 미생물 조성물의 불필요한 낭비가 회피된다.
키트
본 발명의 추가 양태에 따르면, 제1 박테리아 개체군을 선택적으로 저해하는 작용제 및 상기 기재한 방법에서 작용제를 사용하기 위한 지침을 포함하는 키트가 제공된다.
약제학적 조성물을 제조하는 방법
본 발명은 또한 본 발명에 따른 방법에 의해 원치 않는 유기체에 대해 테스트하는 단계를 포함하는, 치료용 박테리아를 포함하는 약제학적 조성물을 제조하는 방법을 제공한다. 이러한 방법은 (a) 치료용 박테리아를 배양하는 단계, (b) 단계 (a)의 배양물의 적어도 일 분획에 대해 본 발명에 따른 방법을 수행하는 단계 및 (c) 단계 (a)의 배양된 치료용 박테리아를 약제학적 조성물로 제형화하는 단계를 포함할 수 있다. 일부 실시형태에서, 본 발명에 따른 방법은 약제학적 조성물의 제형화 후에 수행될 수 있다.
일부 실시형태에서, 약제학적 조성물은 본 발명에 따라 제조되고 테스트되며, 여기서 벌크 치료용 박테리아 배양물의 샘플이 테스트되고, 원치 않는 유기체의 허용 가능한 수준(바람직하게는, 미리 정의된 허용 가능한 수준)이 발견되면, 벌크 치료용 박테리아가 (예를 들어, 약제학적으로 허용 가능한 부형제와 혼합함으로써) 약제학적 조성물의 제형에 사용된다. 원치 않는 유기체의 허용 가능한 수준(바람직하게는, 미리 정의된 허용 가능한 수준)을 초과함이 발견되면, 벌크 치료용 박테리아 배양물은 약제학적 조성물의 제형에 사용되지 않으며, 예를 들어 벌크 치료용 박테리아 배양물은 파괴될 수 있다. 바람직하게는, (예를 들어, 미리 정의된) 허용 가능한 수준은 (i) 103 CFU/g 또는 CFU/㎖ 미만의 총 호기성 미생물 함량(치료용 박테리아 제외), 또는 (ii) 102 CFU/g 또는 CFU/㎖ 미만의 총 합한 효모 및 곰팡이 수; 바람직하게는 (i) 및 (ii) 둘 다이다. 더 바람직하게는, 미리 정의된 허용 가능한 수준은 또한 임의의 에쉬리키아 콜라이 박테리아의 부재를 필요로 한다(예를 들어, 배양물은 검출 가능한 에쉬리키아 콜라이 박테리아를 포함하지 않음).
일 실시형태에서, 벌크 치료용 박테리아 배양물의 샘플은 총 벌크 치료용 박테리아 배양물의 1 부피% 미만, 예를 들어 0.9 부피%, 0.8 부피%, 0.7 부피%, 0.6 부피%, 0.5 부피%, 0.4 부피%, 0.3 부피%, 0.2 부피%, 또는 0.1 부피% 미만을 포함할 수 있다. 일 실시형태에서, 벌크 치료용 박테리아 배양물의 샘플은 총 벌크 치료용 박테리아 배양물의 10 부피% 미만, 예를 들어 9 부피%, 8 부피%, 7 부피%, 6 부피%, 5 부피%, 4 부피%, 3 부피%, 2 부피%, 또는 1 부피% 미만을 포함할 수 있다. 바람직한 실시형태에서, 테스트되는 벌크 치료용 박테리아 배양물의 샘플은 약제학적 조성물의 제형에서 사용되지 않는다. 일 실시형태에서, 벌크 치료용 박테리아 배양물은 적어도 1 리터, 2 리터, 3 리터, 4 리터, 5 리터, 6 리터, 7 리터, 8 리터, 9 리터, 또는 10 리터이다. 일 실시형태에서, 벌크 치료용 박테리아 배양물은 적어도 100 리터, 200 리터, 300 리터, 400 리터, 500 리터, 600 리터, 700 리터, 800 리터, 또는 900 리터이다. 일 실시형태에서, 벌크 치료용 박테리아 배양물은 적어도 1,000 리터, 2,000 리터, 3,000 리터, 4,000 리터, 5,000 리터, 6,000 리터, 7,000 리터, 8,000 리터, 9,000 리터, 또는 10,000 리터이다.
파지 조성물
본 발명은 또한 선택적으로 안정화제, 방부제 및/또는 첨가제와 함께, 하나 이상의 파지를 포함하는 조성물을 제공한다. 일 실시형태에서, 조성물은 복수의 파지를 포함하며, 예를 들어 2, 3, 4, 5, 6, 7, 8, 9, 10가지 또는 10가지 초과의 파지가 이용될 수 있다.
하나 이상의 파지는 본 명세서에 기재된 임의의 파지일 수 있다. 하나 이상의 파지는 자연적으로 발생하는 파지 또는 비-자연적으로 발생하는 파지일 수 있으며, 예를 들어 하나 이상의 파지는 유전자 조작되거나 유전자 변형될 수 있다. 일 실시형태에서, 조성물은 자연적으로 발생하는 파지 및 비-자연적으로 발생하는 파지의 혼합물을 포함할 수 있다. 대안적으로/추가적으로, 조성물은 하나 이상의 치료용 박테리아에 더 특이적 또는 덜 특이적이도록 유전자 조작된 하나 이상의 파지를 포함할 수 있다. 조성물은 그람 양성 박테리아에 특이적인 적어도 하나의 파지를 포함할 수 있고, 선택적으로 그람 음성 박테리아에 특이적인 파지를 포함하지 않는다. 조성물은 그람 음성 박테리아에 특이적인 적어도 하나의 파지를 포함할 수 있고, 선택적으로 그람 양성 박테리아에 특이적인 파지를 포함하지 않는다. 조성물은 DNA 게놈을 갖는 적어도 하나의 파지를 포함할 수 있다.
조성물은 하나의 치료용 박테리아에 특이적인 하나 이상의 파지를 포함할 수 있고, 선택적으로 임의의 다른 치료용 박테리아에 특이적인 임의의 파지를 포함하지 않는다. 조성물은 하나 이상의 파지를 포함할 수 있으며, 각각의 파지는 하나의 치료용 박테리아에 특이적이고, 선택적으로 각각의 파지는 상이한 치료용 박테리아에 특이적이다. 조성물은 치료용 박테리아의 하나의 속 또는 치료용 박테리아의 하나의 종에 특이적인 하나 이상의 파지를 포함할 수 있다. 조성물은 치료용 박테리아의 하나의 균주에 특이적인 하나 이상의 파지를 포함할 수 있다. 실시형태에서, 조성물은 치료용 박테리아의 동일한 속에 특이적인 하나 초과의 파지를 포함하지 않는다. 실시형태에서, 조성물은 치료용 박테리아의 동일한 종에 특이적인 하나 초과의 파지를 포함하지 않는다. 실시형태에서, 조성물은 치료용 박테리아의 동일한 균주에 특이적인 하나 초과의 파지를 포함하지 않는다. 조성물은 치료용 박테리아의 하나 초과의 균주에 특이적인 파지를 포함할 수 있으며, 선택적으로 동일한 종의 치료용 박테리아의 하나 초과의 균주에 특이적인 파지를 포함할 수 있다. 조성물은 동일한 속의 치료용 박테리아의 하나 초과의 종에 특이적인 파지를 포함할 수 있다.
조성물은 장내구균 박테리아에 특이적인 하나 이상의 파지를 포함할 수 있으며, 선택적으로 상기 조성물은 장내구균 박테리아에 특이적이지 않은 임의의 파지를 포함하지 않는다. 대안적으로, 조성물은 장내구균 박테리아에 특이적인 하나 이상의 파지 및 하나 이상의 비-장내구균 치료용 박테리아에 특이적인 하나 이상의 파지를 포함할 수 있다.
본 명세서에 개시된 바와 같이, 치료용 박테리아가 장내구균 박테리아인 경우, 특히 적합한 파지는 NCIMB 43666 파지 및 NCIMB 43667 파지를 포함하며, 이들 둘 다 장내구균 박테리아, 특히 엔테로코커스 갈리나룸 균주 NCIMB 42488에 특이적이다. 일 실시형태에서, 조성물은 NCIMB 43666 파지, NCIMB 43667 파지, 또는 둘 다를 포함한다. 이들 파지는 엔테로코커스 갈리나룸 균주 NCIMB 42488에 매우 특이적이며 배지에 존재할 수 있는 다른 원치 않는 미생물에 영향을 미치지 않는 것으로 밝혀졌다. 따라서 이들 파지는 엔테로코커스 갈리나룸 균주 NCIMB 42488의 성장을 특이적으로 저해하는 데 적합한 작용제이다.
일 실시형태에서, 조성물은 서열번호 1 및/또는 서열번호 2와 적어도 85% 동일한 DNA 게놈을 갖는 파지를 포함한다. 조성물은 서열번호 1 또는 서열번호 2에 제시된 게놈 서열을 갖는 파지에 기능적으로 동등한 파지를 포함할 수 있다.
일 실시형태에서, 조성물은 서열번호 3 내지 8 또는 3 내지 68 및/또는 서열번호 69 내지 74 또는 69 내지 2626와 적어도 85% 동일한 DNA 게놈을 갖는 파지를 포함한다. 조성물은 서열번호 3 내지 8 또는 3 내지 68 또는 서열번호 69 내지 74 또는 69 내지 2626에 제시된 게놈 서열을 갖는 파지에 기능적으로 동등한 파지를 포함할 수 있다.
실시예
본 발명은 이제 하기 실시예를 참조하여 상세하게 기재되며, 하기 실시예는 단지 예시로 제공되고 본 발명의 사상 및 범주를 어떤 식으로든 제한하는 것으로 간주되어서는 안 되며, 오로지 첨부된 청구범위를 참조하여서만 결정되어야 한다.
실시예는 다음과 같은 첨부된 도면을 참조한다:
도 1은 파지 및 박테리아 DNA의 제한효소 단편 길이 다형성(restriction fragment length polymorphism) 분석을 위한 겔 전기영동 결과를 나타낸다;
도 2는 NCIMB 43667의 추정 유전자 분석을 나타낸다.
도면은 예시의 목적으로만 제공되며 본 발명은 도면에 의해 제한되는 것으로 해서되어서는 안 된다.
실시예 1
하기 실시예 2에 기재된 실험에서, 사용된 파지 중 하나는 NCIMB 43667 파지이다. 이 파지를 다수의 방식으로 분석하였다.
7㎖의 멸균 NCIMB 43667 파지 용해물을 사용하여 파지 DNA를 추출하였다. 몇 방울의 클로로포름을 용해물에 첨가하고 혼합물을 3000×g에서 5분 동안 원심분리하였다. 상청액을 0.2 μM 주사기 필터를 통해 여과하였다. 5㎖의 여과액을 수집하고 43㎕의 1 ㎎/㎖ DnaseI 및 39㎕의 5 ㎎/㎖ Rnase A와 혼합하였다. 혼합물을 37℃에서 30분 동안 인큐베이션하였다. 그 다음 91.2㎕의 20% SDS 및 23.8㎕ 프로테이나제 K를 15 ㎎/㎖로 첨가하였다. 혼합물을 37℃에서 30분 동안 추가로 인큐베이션하였다. 전체 부피를 새로운 15㎖ 원심분리 튜브로 옮겼다. 용액을 페놀/클로로포름(pH 8)과 1:1로 혼합하였다. 1500 x g에서 5분 동안 원심분리하여 상을 분리하였다. 수성상을 새로운 15㎖ 튜브로 제거하고 단계를 반복하였다. 수성상을 제거하고 동량의 클로로포름으로 1회 추출하였다. 6000×g에서 5분 동안 원심분리한 후 상부 상을 제거하였다. 10㎕의 3 M 아세트산나트륨과 1 부피의 100% 아이소프로판올을 첨가하였다. DNA를 실온에서 20분 동안 침전시킨 다음, 14000×g에서 20분 동안 원심분리하였다. DNA 펠릿을 70% 에탄올로 세척하였다. 에탄올을 제거하고 DNA 펠릿을 실온에서 10분 동안 건조시켰다. DNA를 500㎕ 5mM Tris-HCl(pH 8.5)에 재현탁시켰다.
농도를 결정하기 위해, DNA를 물에 1:10으로 희석시키고 260㎚ 및 280㎚에서 흡광도를 결정하였다. 결정 결과는 하기 표 1에 제시되어 있다.
박테리아가 아닌 파지 DNA가 단리되었는지를 확인하기 위해, 제한효소 단편 길이 다형성(RFLP) 분석을 수행하였다. 대조군을 제공하기 위해, 제조업체의 프로토콜에 따라 Qiagen DNeasy Blood & Tissue Kit를 사용하여 이. 갈리나룸 유래의 총 박테리아 DNA를 추출하였다. 5㎖의 밤새 배양한 배양물로부터의 박테리아 펠릿을 추출에 사용하였다. 박테리아 DNA의 농도를 상기 기재된 바와 같이 결정하였다. 결과는 하기 표 2에 나타나 있다.
파지 DNA를 다양한 제한 효소로 분해하였다. 각각의 반응에 500 ng의 DNA를 사용하였다. 하기 표 3에 나타낸 바와 같이, 각각의 효소 1 단위를 20㎕ 부피로 반응에 사용하였다.
인큐베이션 후, DNA 로딩 염료를 첨가하고, 샘플에 대해 1 ㎍/㎖ 에티디움 브로마이드로 염색한 1% 아가로스 겔에서 겔 전기영동을 수행하였다. 효소 EcoRI 및 EcoRV는 파지 DNA에 대해 뚜렷한 DNA 단편 패턴을 제공하였다. 효소 HindIII을 사용하여 이. 갈리나룸 DNA를 절단하였다. 박테리아 DNA에 대한 제한 효소 분해 패턴은 파지 DNA에 대해 얻은 것과 분명히 상이하였다. 이는 도 1에 나타나 있다. RFPL 분석으로 파지 DNA가 dsDNA임을 증명한다. 파지 DNA 제제는 품질이 양호하고 이에는 박테리아 DNA 오염이 없었다. DNA는 서열결정에 적합하였다.
그 다음 DNA 라이브러리를 생산하기 위한 종래 프로토콜을 사용하여 DNA의 서열을 결정하였다. 최소 커버리지 30x에서 Illumina 차세대 서열 데이터를 생성하였다. 224개의 콘티그를 얻었으며, 이들 중 단지 3개만 1,000 bp보다 길었다. 파지의 DNA 서열을 나타내는 가장 큰 콘티그는 길이가 57201 bp이었으며, 평균 커버리지는 1,756.31이었다. 완전한 게놈 서열은 상기 기재된 바와 같이 서열 목록의 서열번호 1로 제공되어 있다.
DNA 서열은, A 함량이 31.51%이고; C 함량이 19.56%이며; G 함량이 21.95%이고; T 함량이 26.98%이며; CG 백분율이 41.51%였다.
박테리아 게놈 및 플라스미드 내 프로파지 서열의 식별 및 주석을 위해 PHASTER 웹 서버를 사용하여 추정 유전자에 주석을 달았다. DNA 서열의 말단은 분석하지 않았다. 따라서 파지 게놈이 선형인지 환형인지 결정하는 것은 불가능하였다. 추정 유전자 분석은 도 2에 나타나 있다.
매우 유사한 서열 검색 알고리즘(megablast)이 있는 BlastN 검색 도구를 사용하여 NCBI 데이터베이스의 서열과 유사한 서열에 대해 NCIMB 43667 파지의 57,202 bp 서열을 검색하였다. NCIMB 43667 서열과 매우 높은 유사성을 나타낸 서열은 엔테로코커스 파지 vB_EfaS_Ef7.1 및 엔테로코커스 파지 VD13의 서열이었다. 매우 유사한 서열에 대한 megablast 히트 표는 하기 표 4에 나타나 있다.
NCIMB 43667 파지의 특성은 본 발명의 방법에서 유용할 가능성이 있음을 나타낸다. 이는 다음 실시예 2에 나타나 있다.
실시예 2
WO 2017/085520에서 입증된 바와 같이, 엔테로코커스 갈리나룸 종의 균주는 암을 치료 및 예방하는 데 효과적이다. 따라서, 이들 종은 상기 정의된 바와 같은 치료용 박테리아이다. 엔테로코커스 갈리나룸의 특정 균주는 수탁 번호 NCIMB 42488로 기탁되었으며 WO 2017/085520에 더 상세히 기재되어 있다.
NCIMB 42488을 포함하는 미생물 조성물은 캡슐로 공급되었다. 각각의 캡슐은 약 5×1010 CFU의 이. 갈리나룸을 포함하였다. 캡슐은 사용하기 전에 5±3℃에서 보관하였다.
하기 제시된 실험은 2가지 박테리오파지, 즉, NCIMB 43666 및 NCIMB 43667의 사용을 포함한다.
실험 상세내용 및 결과
파지 역가의 결정을 위한 이중 한천 오버레이 분석
파지 검출 과정은 숙주 세포의 론(lawn)에서 명확한 구역(플라크)을 형성하는 파지의 능력에 기반한다. 이 연구에 이중 한천 오버레이 분석을 적용하였다.
파지 도말의 경우, SM 완충액 중 100㎕의 파지 희석액을 NCIMB 42488의 밤새 배양한 배양물 500㎕와 혼합하고 37℃에서 15분 동안 인큐베이션하였다. 42℃로 가온하고 CASO 한천 위에 고르게 분포된 3㎖의 상단 한천에 파지-숙주 혼합물을 첨가하였다. 37℃에서 16 내지 48시간 동안 플레이트를 인큐베이션하고 플라크 형성에 대해 검사하였다. 파지 역가는 플라크 수가 10 내지 300인 플레이트로부터 결정되었다. 다음 방정식을 사용하여 1㎖의 플라크 형성 단위의 수를 계산하였다:
여기서:
플라크 수의 가중 평균
∑c 계산에 사용된 모든 플레이트의 플라크 합계
n 1 희석률이 가장 낮은 플레이트의 수
n 2 다음으로 희석률이 가장 높은 플레이트의 수.
다음 방정식을 사용하여 1㎖의 플라크 형성 단위의 수를 계산하였다:
pfu/㎖ = 가중 평균 가장 낮은 희석의 역수
NCIMB 43667 파지 용해물의 생산 및 품질 관리
NCIMB 42488에 대한 파지 칵테일을 포함하는 액체 및 고체 배지의 생산에 추가로 사용되도록 NCIMB 43667 파지 용해물의 벌크 부피를 생산하였다. 균주의 밤새 배양한 배양물 5㎖를 포함하는 95㎖ CASO 부용(bouillon)을 접종함으로써 NCIMB 42488의 기하급수적으로 성장하는 배양물을 준비하였다. 희석된 배양물을 37℃에서 1시간 동안 추가로 인큐베이션하고 10㎕ NCIMB 43667 파지로 감염시켰다. 감염에 사용된 NCIMB 43667 파지 접종물을 필터-멸균 샘플로부터 준비하였다. 감염 후, 용해될 때까지 16시간 동안 교반 없이 배양물을 추가로 인큐베이션하였다. 용해물을 풀링하고, 1㎖ 클로로포름을 첨가한 다음, 와류를 사용하여 혼합하고 3000×g에서 5분 동안 원심분리하였다. 상청액을 필터-멸균하였다. 파지의 역가를 상기 기재된 바와 같이 결정하였다. 결과는 표 5에 제공되어 있다.
확산 도말(spread plate) 방법을 사용하여 파지의 멸균성을 테스트하였다. 100㎕의 NCIMB 43667 용액을 CASO 한천에 이중으로 확산-도말하고 32.5±2.5℃에서 48시간 동안 인큐베이션하였다. 결과는 표 6에 제공되어 있다. NCIMB 43667 용액을 사용할 때까지 5±3℃에서 2개의 40㎖ 분취량으로 보관하였다.
방법 개발 연구에서 이전에 결정된 역가의 50% 이상으로 파지 제제의 최저 허용 농도 기준을 설정하였다.
NCIMB 43666 파지 용해물의 생산 및 품질 관리
NCIMB 42488에 대한 파지 칵테일을 포함하는 액체 및 고체 배지의 생산에 추가로 사용되도록 NCIMB 43666 파지 용해물의 벌크 부피를 생산하였다. NCIMB 43666 파지의 십진수 희석 시리즈를 SM 완충액에서 준비하였다. NCIMB 42488의 밤새 배양한 배양물 0.5㎖와 함께 100㎕의 부피로 10-3, 10-4 및 10-5 희석물을 도말하였다. 5mM MgSO4 + 5mM CaCl2가 보충된 LB 한천 플레이트를 사용하였다. 각각의 희석물을 상기 기재된 방법을 사용하여 사중으로 도말하였다. 플레이트를 37℃에서 16 내지 48시간 동안 인큐베이션하였다. 컨플루언트 용해를 나타내는 플레이트를 3D 회전기에서 5㎖ SM 완충액/플레이트로 4시간 동안 세척하였다. 용해물을 풀링하고, 0.5㎖ 클로로포름을 첨가한 다음, 와류를 사용하여 혼합하고 3000×g에서 5분 동안 원심분리하였다. 상청액을 필터 멸균하였다. NCIMB 42488의 역가를 상기 기재된 바와 같이 결정하였다(결과는 표 7에 나타냄). 확산 도말 방법을 사용하여 파지의 멸균성을 테스트하였다. 100㎕ 부피의 파지를 CASO 한천에 이중으로 확산-도말하고 32.5±2.5℃에서 48시간 동안 인큐베이션하였다(결과는 표 8에 나타냄). 파지를 사용할 때까지 5±3℃에서 1개의 20㎖ 분취량으로 보관하였다.
상기 제시된 바와 같이 결정된 역가의 50% 이상으로 파지 제제의 최저 허용 농도 기준을 설정하였다.
NCIMB 43667 및 NCIMB 43666 파지 칵테일의 생산
2가지 파지 스톡 용액을 사용 직전에 동일한 부피로 혼합하였다. 칵테일 중 파지의 최종 농도는 NCIMB 43666 및 NCIMB 43667이 각각 2.85×108 및 1.2×109 PFU/㎖이었다. 파지 칵테일을 사용하여 오염 물질 미생물의 검출에 사용되는 한천 플레이트를 덮었다.
테스트 균주의 준비
테스트 균주를 43% 글리세롤이 포함된 저온 스톡으로 준비하고 -64℃ 이하에서 보관하였다. 승인된 배지 배치에서 세포 수를 결정하였다. 하기 표 9에 표시된 바와 같이 100㎕에서 100 CFU 미만을 얻도록 펩톤수 중 희석액을 준비하였다.
파지가 있는 고체 배지의 성장 촉진 특성
대조군 오염 물질 미생물을 완충된 펩톤수에서 103 CFU /㎖ 미만으로 희석시키고 100㎕의 희석액을 CASO 또는 컬럼비아 혈액 한천(Columbia blood agar)에 확산-도말하였다. 플레이트를 100㎕ 파지 칵테일로 덮고 대조군 미생물을 도말하기 전에 건조시켰다. 각각의 균주 제제를 이중으로 도말하였다. 씨. 스포로게네스 ATCC 19404가 있는 컬럼비아 한천 플레이트를 Anaerobic Jar GasPack 시스템으로 형성된 혐기성 분위기에서 32.5±2.5℃에서 48시간 이하 동안 인큐베이션하였다. 에스. 아우레우스 ATCC 6538 및 비. 세레우스 ATCC 11778가 있는 CASO 한천 플레이트를 32.5±2.5℃에서 18시간 이하 동안 호기성으로 인큐베이션하였다. 허용 기준 및 결과는 표 10에 제시되어 있다.
액체 배지의 성장 촉진 특성, 테스트 방법의 적합성 및 오염 미생물의 부재에 대한 테스트
샘플의 준비
층상 공기 유동 캐비닛(laminar air flow cabinet)에서 화염 핀셋을 사용하여 블리스터로부터 멸균으로 NCIMB 42488 완제 의약품의 각각의 테스트된 캡슐을 제거하고 10㎖ 완충 펩톤수에 현탁시켰다. 약 30분 인큐베이션 후 캡슐 쉘을 용해시키고 내용물을 와류에 의해 균질화하였다. 사용 전에 2 내지 8℃에서 8시간 이하로 현탁액을 보관하였다. 테스트를 위해, 현탁액의 전체 부피(10㎖)를 꺼냈다. 다음으로 적절한 배양 배지 10㎖를 이용한 단일 세척 단계에 의해 잔여 부피를 수집하였다.
테스트 절차
오염 물질 박테리아의 검출을 위한 테스트를 2 단계로 수행하였다. 제1 단계는 이. 갈리나룸 NCIMB 42488에 대해 활성인 샘플 및 박테리오파지 칵테일과 함께 액체 배양물에서 잠재적인 오염 물질 균주를 농축하는 것이었다. 제2 단계는 앞서 파지 칵테일로 덮인 한천 플레이트에서 농축물을 계대 배양하는 것이었다.
테스트한 균주에 따라, CASO 브로스(에스. 아우레우스 ATCC 6538 및 비. 세레우스 ATCC 11778)에서 또는 RCM 브로스(씨. 스포로게네스 ATCC 19404)에서 농축이 이루어졌다. 두 배지를 5mM MgSO4로 보충하였다. CASO 배양물을 진탕 없이 32.5±2.5℃에서 24시간 동안 인큐베이션하고 RCM 배양물을 동일한 조건 하에서 48시간 동안 인큐베이션하였다. 각각의 농축은 다음으로 이루어졌다:
990㎖ 브로스(RCM 또는 CASO);
1㎖ NCIMB 43667 파지;
0.2㎖ NCIMB 43666 파지;
10㎖ 샘플(펩톤수 중 1 캡슐) 또는 10㎖ 펩톤수; 및
적절한 경우 100㎕의 테스트 균주(100 CFU 미만).
농축 후, CASO 한천(에스, 아우레우스 ATCC 6538 및 비. 세레우스 ATCC 11778) 및 컬럼비아 혈액 한천(씨. 스포로게네스 ATCC 19404) 상에서 계대 배양이 이루어졌다. 계대 배양 전에 확산-도말함으로써 한천 플레이트를 100㎕ 파지 칵테일로 덮고 층상 유동 캐비닛에서 건조시켰다. 각각의 농축물로부터 삼중으로 10㎕ 연속 희석에 의해 계대 배양을 수행하였다. CASO 한천 플레이트를 32.5±2 내지 5℃에서 24시간 동안 호기성으로 인큐베이션하고 컬럼비아 혈액 한천 플레이트를 혐기성 분위기에서 48시간 동안 인큐베이션하였다. 다음 계획에 따라 테스트를 수행하였다(표 11):
액체 배지 및 음성 대조군의 성장-촉진 특성
액체 배지의 성장 촉진 특성을 상기 기재된 바와 같이 테스트하였다. 오염 물질 균주의 농축에서 샘플 대신에 희석액(펩톤수)을 사용하였다. 결과는 표 12에 제시되어 있다. 이 연구에서 사용된 CASO 브로스 및 RCM 브로스 배치는 둘 다 명시된 미생물에 대한 성장 촉진 특성을 나타내었고 이 연구에서 사용하도록 승인되었다. 음성 대조군은 CASO 배치에는 에스. 아우레우스 ATCC 6538 및 비. 세레우스 ATCC 11778이 없고 RCM 브로스에는 씨. 스포로게네스 ATCC 19404가 없음을 입증하였다.
NCIMB 42488에서 에스. 아우레우스, 비. 세레우스 및 씨. 스포로게네스의 검출에 대한 방법 적합성
상기 기재된 바와 같이 테스트 균주를 제조하였다. 검출에 적합한 방법을 입증하기 위해 샘플의 존재 하에 적은 수의 테스트 균주의 회수를 테스트하였다. 상기 기재된 바와 같이 테스트를 수행하였다. 테스트한 각각의 균주에 대해, 농축 단계를 3회 반복하였다. 각각의 농축 후 계대 배양하는 단계를 또한 3중으로 수행하였다. 결과는 표 13에 제시되어 있다.
방법은 약 5×1010 CFU/캡슐을 포함하는 NCIMB 42488의 1개 캡슐의 존재 하에 에스. 아우레우스 ATCC 6538, 비. 세레우스 ATCC 11778 및 씨. 스포로게네스 ATCC 19404의 검출에 적합한 것으로 입증되었다. 육안으로 에스. 아우레우스로 식별된 콜로니를 선별하여 제조업체의 지침에 따라 Staphaurex™ 라텍스 응집 테스트를 통해 정체성을 확인하였다. 에스. 아우레우스는 라텍스 테스트에서 양성 반응을 나타낸 반면, NCIMB 42488은 음성 반응을 나타낸다. 비. 세레우스의 검출을 콜로니 형태 및 그람 염색 후 현미경으로 확인하였다. 내생포자를 형성하는 그람-양성 간균의 존재로 비. 세레우스의 검출을 확인하였다.
컬럼비아 혈액 한천에서 특징적인 콜로니의 발생 및 간상 그람-양성 세포(내생포자가 있거나 없음)의 검출로 카탈라제 테스트에서 음성 결과를 보여 씨. 스포로게네스의 검출을 확인하였다. 특징적인 콜로니는 가근 모양의 가장자리와 융기된 중심부를 가지면서 크고 편평하다. 콜로니의 가장자리는 건조하고 거칠다.
NCIMB 42488에서 에스. 아우레우스, 비. 세레우스 및 씨. 스포로게네스의 존재에 대한 테스트.
NCIMB 42488 완제 의약품에서 에스. 아우레우스, 비. 세레우스 및 씨. 스포로게네스의 존재를 결정하기 위해, 상기 기재된 바와 같이 테스트를 수행하였다. 3개의 캡슐을 각각 테스트 균주의 부재에 대해 개별적으로 테스트하였다(균주당 3개 농축). 각각의 농축으로부터의 계대 배양을 3중으로 하였다. 준비된 플레이트 중 임의의 것에서 계대 배양한 후 테스트 미생물의 콜로니가 발견되지 않을 때 테스트 미생물이 부재하는 것으로 표시하였다. 결과는 표 14에 제시되어 있다. 상기-언급된 오염 물질 균주 중 어느 것도 NCIMB 42488 완제 의약품 캡슐에서 발견되지 않았다.
결론
기재된 방법은 문헌[Ph. Eur. 2.6.38]의 요구 사항에 따라 이. 갈리나룸 NCIMB 42488의 1개 캡슐에서 스타필로코커스 아우레우스 ATCC 6538, 바실러스 세레우스 ATCC 11778 및 클로스트리듐 스포로게네스 ATCC 19404의 검출(CFU/캡슐)에 적합하다. 파지 칵테일의 사용은 이. 갈리나룸 NCIMB 42488 세포의 충분한 감소를 가능하게 하여 오염 물질 균주의 검출을 가능하게 할 수 있다.
상기 언급한 오염 물질 균주 중 어느 것도 이. 갈리나룸 NCIMB 42488 완제 의약품 캡슐에서 발견되지 않았다.
실시예 3
실험 상세내용 및 결과
파지 역가의 결정을 위한 이중 한천 오버레이 분석
파지 검출 과정은 숙주 세포의 론에서 명확한 구역(플라크)을 형성하는 파지의 능력에 기반한다. 이 연구에 이중 한천 오버레이 분석을 적용하였다.
파지 도말의 경우, SM 완충액 중 100㎕의 파지 희석액을 NCIMB 42488의 밤새 배양한 배양물 500㎕와 혼합하고 37℃에서 15분 동안 인큐베이션하였다. 42℃로 가온하고 CASO 한천 위에 고르게 분포된 3㎖의 상단 한천에 파지-숙주 혼합물을 첨가하였다. 37℃에서 16 내지 48시간 동안 플레이트를 인큐베이션하고 플라크 형성에 대해 검사하였다. 파지 역가는 플라크 수가 10 내지 300인 플레이트로부터 결정되었다. 다음 방정식을 사용하여 1㎖의 플라크 형성 단위의 수를 계산하였다:
여기서:
플라크 수의 가중 평균
∑c 계산에 사용된 모든 플레이트의 플라크 합계
n 1 희석률이 가장 낮은 플레이트의 수
n 2 다음으로 희석률이 가장 높은 플레이트의 수.
다음 방정식을 사용하여 1㎖의 플라크 형성 단위의 수를 계산하였다:
pfu/㎖ = 가중 평균 가장 낮은 희석의 역수
NCIMB 43667 파지 용해물의 생산 및 품질 관리
SM 완충액에서 NCIMB 43667 파지의 10-4, 10-5, 10-6, 10-7 및 10-8 희석액을 준비하였다. 각각의 희석액 100㎕를 밤새 배양한 NCIMB 42488(CASO 브로스 중, 37℃, 교반 없음) 500㎕와 함께 3㎖의 용융된 상부 한천에 3중으로 도말하였다. 보충된 LB 한천을 사용하였다. 플레이트를 37℃에서 18시간 동안 인큐베이션하였다. 컨플루언트 용해를 나타내는 플레이트를 3D 회전기에서 5㎖ SM 완충액/플레이트로 4시간 동안 세척하였다. 파지 용해물을 풀링하고, 0.5㎖ 클로로포름을 첨가하였다. 혼합물을 3000×g에서 5분 동안 원심분리하였다. 상청액을 필터 여과하고 멸균 DMSO를 최종 농도 7%로 첨가하였다. 0.5㎖의 분취량을 준비하고 사용할 때까지 -64℃ 이하에서 보관하였다.
NCIMB 43667 파지 스톡 중 파지 역가를 결정하기 위해, 하나의 WCB를 해동하였다. NCIMB 42488의 밤새 배양한 배양물 500㎕와 함께 SM 완충액 중 파지의 100㎕ 희석액을 도말함으로써 CASO 한천에서 파지 역가를 결정하였다. 결과는 하기 표 15에 있다.
NCIMB 43666 파지 스톡 용액의 생산
상기 기재된 절차를 사용하여 NCIMB 43666 파지 스톡 용액을 준비하였다. 0.5㎖의 분취량을 준비하고 -64℃ 이하에서 보관하였다. NCIMB 42488의 밤새 배양한 배양물 500㎕와 함께 SM 완충액 중 파지의 100㎕ 희석액을 도말함으로써 CASO 한천에서 파지 역가를 결정하였다. 결과는 하기 표 16에 나타나 있다.
NCIMB 43667 및 NCIMB 43666 파지 칵테일의 생산
2가지 파지 스톡 용액을 사용 직전에 1:1로 혼합하였다. 파지의 최종 농도는 10㎕ 칵테일 중 NCIMB 43666이 2.6×106 PFU이고 NCIMB 43667이 1.1×106 PFU였다.
NCIMB 42488을 포함하는 액체 배양물에서 파지 활성의 결정
NCIMB 42488의 밤새 배양한 배양물을 CASO 브로스에서 준비하였다. 배양물을 1:100으로 희석시키고 멸균 96-웰 역가 플레이트 중 100㎕ 분취액을 준비하였다. 각각의 분취액에 1, 10, 100, 및 1000 NCIMB 43667 및 NCIMB 43666을 각각 및 조합하여(1:1 칵테일로) 포함하는 10㎕로 스파이킹하였다. 추가적으로 희석되지 않은 파지 스톡 용액을 테스트하였다: 2.2×106 PFU의 NCIMB 43667 파지 및 5.2×106 PFU의 NCIMB 43666. 파지를 SM 완충액에서 원하는 농도로 희석시켰다. 박테리아 배양물의 탁도 변화(OD620㎚)의 동역학을 6시간 인큐베이션 동안 30분 간격으로 측정하였다.
파지 NCIMB 43667은 파지 NCIMB 43666보다 NCIMB 42488에 대하여 훨씬 더 나은 성능을 나타내었다. 파지 NCIMB 43666은 스파이킹된 파지 양에 관계 없이 액체 배양물을 용해할 수 없었다. 배양물에 5.2×106 PFU의 NCIMB 43666을 스파이킹하였을 경우 NCIMB 42488의 약간 더 느린 성장이 관찰되었다. NCIMB 43667 파지를 스파이킹한 배양물은 심지어 처음에 매우 적은 수의 파지가 배양물에 있었을 때에도 약 4시간 후 완전히 용해되었다. 많은 수의 NCIMB 43667 파지(2.2×106 PFU)를 스파이킹한 배양물은 전혀 성장을 나타내지 않았다. 이러한 데이터는 NCIMB 43667 파지가 NCIMB 42488에서 용해 사이클을 통해 복제하고 NCIMB 42488을 포함하는 조성물의 미생물 검사에서 이. 갈리나룸의 중화를 위해 작용제로서 사용되는 매우 우수한 후보임을 나타낸다. 두 파지를 포함하는 파지 칵테일을 사용하였을 때 NCIMB 42488 살해 활성의 개선 증거는 관찰되지 않았다. NCIMB 42488 특이적 파지의 존재 하에 박테리아의 완전한 용해 및 더 이상의 성장이 없다는 것은 테스트한 샘플이 미생물학적으로 순수함을 나타낸다.
미생물 오염 물질의 계수 테스트
테스트 균주를 43% 글리세롤이 포함된 저온 스톡으로 준비하고 -64℃ 이하에서 보관하였다. 이전에 세포 수를 결정하였다. 하기 표에 표시된 바와 같이 100㎕에서 100 CFU 미만을 얻도록 펩톤수 중 희석액을 준비하였다.
테스트 조건을 검증하기 위해, 테스트 제제 대신에 희석제로서 완충된 펩톤수를 사용하여 음성 대조군을 수행하였다. 미생물의 성장이 없어야 한다.
배지의 성장 촉진에 대한 테스트를 다음과 같이 수행하였다:
(A) 100 CFU 미만의 에스. 아우레우스(100㎕) 및 10㎕의 파지 칵테일을 CASO 한천에 확산-도말하였다. 유사하게 피. 아에루기노사 및 비. 서브틸리스를 테스트하였다.
(B) 100㎕의 완충된 펩톤수 및 10㎕의 파지 칵테일을 CASO 한천에 확산-도말하였다
(C) 파지가 없는 100 CFU 미만의 에스. 아우레우스(100㎕)를 CASO 한천에 확산-도말하였다.
피. 아에루기노사 및 비. 서브틸리스를 동일한 방식으로 테스트하고 플레이트 A, B, 및 C를 32.5℃에서 3일 동안 인큐베이션하였다. 허용 기준은 다음과 같았다:
- 플레이트 A 및 C의 에스. 아우레우스, 피. 아에루기노사 및 비. 서브틸리스의 수는 50% 초과로 차이가 나지 않아야 함
- 플레이트 A에서 얻은 성장은 안정적인 에스. 아우레우스, 피. 아에루기노사 및 비. 서브틸리스 접종물에 대해 계산된 값과 2배 초과로 차이가 나지 않아야 함
- 플레이트 B에서 성장이 관찰되지 않음(음성 대조군)
테스트 균주에 대한 모든 허용 기준을 충족하였다. 파지 칵테일을 사용한 테스트 균주와 파지 칵테일을 첨가하지 않은 테스트 균주의 회수에서 유의한 차이는 관찰되지 않았다. 따라서, 파지 칵테일의 사용은 테스트의 유효성에 영향을 미치지 않는다. NCIMB 42488을 포함하는 미생물 오염 물질 조성물의 계수를 위한 테스트에서 NCIMB 42488의 중화를 위한 작용제로서 파지 칵테일을 사용할 수 있다. 파지 칵테일은 이. 갈리나룸에 대해 선택적으로 활성적이고 테스트 균주로부터의 어떤 것도 영향을 받지 않았다.
LBP의 존재 시 계수 방법의 적합성
LBP의 균질한 현탁액을 준비하였다. 2 그램의 NCIMB 42488 샘플(DS)을 18㎖ CASO 브로스(10-1 희석액)에 현탁시켰다. 테스트 물질을 포함하지 않는 대조군을 동일한 방식으로 준비하였다. LBP 현탁액을 1:10 및 1:100으로 더 희석시켜 LBP의 10-2 및 10-3 희석액을 형성하였다.
테스트 균주를 43% 글리세롤이 포함된 저온 스톡으로 준비하고 -64℃ 이하에서 보관하였다. 이전에 세포 수를 결정하였다. 하기 표에 표시된 바와 같이 10㎕에서 100 CFU 미만을 얻도록 펩톤수 중 희석액을 준비하였다.
파지 칵테일을 앞서 기재된 바와 같이 준비하였다. 테스트를 다음과 같이 수행하였다:
(D) 파지가 없는 테스트: 10-1, 10-2, 10-3 LBP 희석액의 1㎖ 분취량에 100 CFU 미만의 에스. 아우레우스(10㎕ 중)를 첨가하였다. 전체 부피를 각각의 DS 희석액에 대해 3개의 CASO 한천 플레이트에 확산-도말하였다. 테스트를 이중으로 수행하였다. 피. 아에루기노사 및 비. 서브틸리스를 동일한 방식으로 테스트하였다.
(E) 파지를 이용한 테스트: 10-1, 10-2, 10-3 LBP 희석액의 1㎖ 분취량에 100 CFU 미만의 에스. 아우레우스(10㎕ 중) 및 10㎕의 파지 칵테일을 첨가하고 짧게 혼합하였다. 전체 부피를 각각의 DS 희석액에 대해 3개의 CASO 한천 플레이트에 확산-도말하였다. 테스트를 이중으로 수행하였다. 피. 아에루기노사 및 비. 서브틸리스를 동일한 방식으로 테스트하였다.
(F) 파지가 없는 테스트는 LBP가 없다: 완충된 펩톤수의 1 ㎖에 100 CFU 미만의 에스. 아우레우스(10㎕ 중)를 첨가하였다. 전체 부피를 3개의 CASO 한천 플레이트에 확산-도말하였다. 테스트를 이중으로 수행하였다. 피. 아에루기노사 및 비. 서브틸리스를 동일한 방식으로 테스트하였다.
(G) 파지를 이용하고 LBP가 없는 테스트: 완충된 펩톤수의 1 ㎖에 100 CFU 미만의 에스. 아우레우스(10㎕ 중) 및 10㎕의 파지 칵테일을 첨가하고 짧게 혼합하였다. 전체 부피를 3개의 CASO 한천 플레이트에 확산-도말하였다. 테스트를 이중으로 수행하였다. 피. 아에루기노사 및 비. 서브틸리스를 동일한 방식으로 테스트하였다.
플레이트 D, E, F, 및 G를 32.5℃에서 3일 동안 인큐베이션하였다.
오염 미생물의 계수를 위해 표면-확산 방법을 선택하였다. 각각의 테스트 균주/DS 희석 조합에 대해 이중으로 플레이트-계수를 수행하였다. 배지당 계수의 산술 평균을 취하고 원래 접종물의 CFU 수를 계산하였다. 플레이트-계수 방법의 적합성을 검증할 때, LBP의 부재 시 대조군의 값과 2배 초과로 차이가 나지 않는 테스트 유기체의 평균수를 얻어야 한다.
LBP 샘플(플레이트 D)로부터 회수된 테스트 미생물의 수를 대조군 제제(플레이트 F)로부터 회수된 테스트 미생물의 수와 비교하였다. 성장이 저해되면(2배 초과로 감소) 문헌[Ph. Eur. figure 2.6.36.1]에 나타낸 의사 결정 나무를 따라야 한다.
LBP 샘플(플레이트 E)로부터 회수된 테스트 미생물의 수를 대조군 제제(플레이트 G)로부터 회수된 테스트 미생물의 수와 비교할 것이다. 성장이 저해되면(2배 초과로 감소) 문헌[Ph. Eur. figure 2.6.36.1]에 나타낸 의사 결정 나무를 따라야 한다.
명시된 미생물에 대한 테스트
LBP의 균질한 현탁액을 준비하였다. 7 그램의 NCIMB 42488 샘플(DS)을 63㎖ 완충된 펩톤수(10-1 희석액)에 현탁시켰다. 테스트 물질을 포함하지 않는 대조군을 동일한 방식으로 준비하였다. LBP 현탁액을 1:10 및 1:100으로 더 희석시켜 LBP의 10-2 및 10-3 희석액을 형성하였다.
테스트 균주를 43% 글리세롤이 포함된 저온 스톡으로 준비하고 -64℃ 이하에서 보관하였다. 이전에 수를 결정하였다. 하기 표에 표시된 바와 같이 100㎕(적은 수의 명시된 미생물)에서 100 CFU 미만을 얻도록 펩톤수 중 희석액을 준비하였다. 추가적으로, 테스트 균주의 희석되지 않은 현탁액을 사용하여 검출 절차의 전반적인 실행 가능성을 평가하였다.
파지 칵테일을 상기 기재된 바와 같이 준비하였다.
각각 100㎕ 부피로 100 CFU 미만의 수를 갖는 테스트 균주 현탁액을 파지 칵테일로 덮거나 덮지 않은 CASO 한천 플레이트에 확산-도말하였다. 플레이트를 32.5℃에서 18시간 미만 동안 인큐베이션하고 미생물의 수를 결정하였다. 파지로 덮은 플레이트를 준비하기 위해, 100㎕의 파지 칵테일을 한천 표면에 확산-도말하고 사용 직전에 건조시켰다.
고체 배지의 저해 특성에 대한 테스트는 적용 가능하지 않았다. 이 연구에 사용된 고체 배지는 에스. 아우레우스 및 비. 세레우스의 배양에 선택적이지 않지만, LBP 미생물의 성장을 선택적으로 저해하고 있다.
LBP의 존재 하에 표적 미생물의 사전 농축을 LBP의 저해 활성을 중화시켜야 하는 파지 칵테일이 보충된 CASO 브로스에서 수행하였다.
90㎖ CASO 브로스에 10㎖의 3가지 상이한 희석액 중 테스트 샘플, 100㎕의 테스트 균주 제제, 및 100㎕의 파지 칵테일을 첨가하였다. 교반 없이 32.5℃에서 18시간 동안 혼합물을 인큐베이션하였다. LBP 대신 10㎖의 완충된 펩톤수를 90㎖ CASO 브로스에 첨가하고, 각각 100 CFU 미만의 테스트 균주 현탁액 100㎕, 및 각각 100㎕의 파지 칵테일을 접종하여 에스. 아우레우스 및 비. 세레우스의 검출을 위한 양성 대조군을 준비하였다. 90㎖ CASO 브로스를 테스트 샘플의 10-1, 10-2, 10-3 희석액 10㎖ 및 100㎕의 파지 칵테일을 접종하여 음성 대조군을 준비하였다. 에스. 아우레우스 또는 비. 세레우스는 첨가하지 않았다.
90㎖ CASO 브로스를 테스트 샘플의 10-1, 10-2, 10-3 희석액 10㎖와 함께 접종하여 미생물 조성물만을 포함하는 참조 샘플을 생산하였다.
교반 없이 32.5℃에서 18시간 동안 모든 배양물을 인큐베이션하였다.
앞서 기재된 바와 같이 준비한 각각의 배양물로부터, CASO 한천에 2개의 10㎕ 희석 줄무늬를 만들었다. 32.5℃에서 18시간 동안 플레이트를 인큐베이션하였다.
파지로 덮은 플레이트를 준비하기 위해, 100㎕의 파지 칵테일을 한천 표면에 확산-도말하고 사용 직전에 건조시켰다. 앞서 기재된 바와 같이 준비한 각각의 배양물로부터의 희석 줄무늬를 파지로 덮은 CASO 한천 플레이트에 만들었다.
32.5℃에서 18시간 동안 플레이트를 인큐베이션하였다.
LBP 전형적인 콜로니의 존재 하에 에스. 아우레우스 콜로니가 관찰될 때마다, 육안으로 에스. 아우레우스로 식별된 적어도 2개의 분리된 콜로니를 선별하여 Staphaurex™ 라텍스 응집 테스트를 사용하여 정체성을 확인하였다. 제조업체의 설명에 따라 테스트를 수행하였다.
LBP 전형적인 콜로니의 존재 하에 비. 세레우스 콜로니가 관찰될 때마다, 육안으로 비. 세레우스로 식별된 적어도 2개의 분리된 콜로니를 선별하여 현미경 검사(내생포자를 형성하는 그람-양성 간균)를 통해 정체성을 확인하였다.
완충된 펩톤수, CASO 브로스 및 파지 칵테일을 CASO 한천에 각각 100㎕의 부피로 확산-도말하였다. 멸균 처리 환경을 테스트하기 위해, 하나의 CASO 한천 플레이트를 층상 유동 벤치 하에 놓고 샘플을 처리하는 동안 열어 두었다. 플레이트를 32.5℃에서 3일 동안 인큐베이션하였다.
명시된 미생물의 검출을 위한 테스트 방법의 적합성에 대한 테스트 결과는 하기 표에 기재되어 있다.
기재된 방법은 DS가 적어도 1:100으로 희석된 경우 비. 서브틸리스의 계수에 적합하며, 즉, 비. 서브틸리스는 0.01g의 DS에서 확실하게 계수될 수 있다. 비. 서브틸리스의 계수의 경우, LBP의 저해 활성을 중화시키는 작용제로서 파지 칵테일의 사용에 의해 어떠한 유의한 개선도 관찰되지 않았다.
상기 방법은 에스. 아우레우스 및 피. 아에루기노사의 계수에 적합하지 않지만, 파지 칵테일의 사용 및 DS의 희석은 LBP의 존재 하에 이들 테스트 미생물의 회수를 현저하게 개선시켰다.
상기 방법은 DS가 적어도 1:1000으로 희석된 경우 LBP의 존재 하에 에스. 아우레우스 및 비. 세레우스의 검출에 적합하며, 즉, 적은 수의 의도적으로 첨가된 테스트 미생물은 0.01g 이하 양의 DS에서 확실하게 검출될 수 있다.
상기 실험은 치료용 박테리아 개체군을 포함하는 미생물 조성물이 임의의 원치 않는 유기체를 포함하는지 여부를 결정하기 위해 본 발명의 방법을 사용하는 것이 가능함을 나타낸다. 이들 실험으로 나타낸 원리는 당업자가 이해할 바와 같이, 치료 용도를 위한 다른 미생물 조성물에 적용될 수 있다.
NCIMB Ltd. NCIMB42488 20151116 NCIMB Ltd. NCIMB43666 20200916 NCIMB Ltd. NCIMB43667 20200916
SEQUENCE LISTING <110> 4D Pharma Leon SLU <120> Process <130> P077226 <141> 2021-11-25 <160> 2626 <170> SeqWin2010, version 1.0 <210> 1 <211> 57074 <212> DNA <213> NCIMB 43667 Genome <400> 1 atgacggtgg ctcaatgact ccggaagctt atgtagaatg gctggctgct aagtctacta 60 cacagcttca agcaggcttt gctcactact atggtaaccg taacacaatg gctcgtgtag 120 aagatactta caatggagct tggcacgtag ctaactacaa tggtaacatg gactatgtcg 180 gatacgaagt ttgtgagtct ctgaaagttt ccgacaaaga cttcatcgca aacgaagaag 240 cggtgttcca acaagccgct aaagacatga aagactgggg actaactcca tctcgtacaa 300 ctgttaagct tcacagagcc tttgtaccga ctgattgccc gcaccgttca tgggcgttgc 360 atgtaggtag aggggcagct gatacaacag ctaaccgcaa caagttggta gactacttcg 420 tagctcgtat caaacactac atgggcggag gaagcaacaa cagcaactcc ggaagcaagc 480 caaatactgg tggaaatagc ggaggcaaca agattaccaa tactactaag tttaataatg 540 gagacaaagt aaaagtcttg gcaaaggcta ctaactatca gactggtcag tctataccaa 600 gctttgtcaa aggtcagact tacactgtca aacaatctaa agtagttaac caatcagtct 660 ccaaatacgc cttcctattg gatggagtta acagctggtt cttggcacaa gacttgcaga 720 aagtctctgg gggctccact ggatatgctg ctaagaaagt tggggacaca gttactgtcc 780 aaagctttgc ctcgcgctat caaacaggag aacctattgc cagctttgta aagggtaaaa 840 agtataagat caagcaggtt aaatctgtca aacagtctaa gtcaaaacgt gcttacctgt 900 tagatggaat ccagtcatgg gttcttgaac aagacgttaa atagcatagt aaaagacctc 960 ccacagtttt tgtgggaggt ctttttgtta ctcttcggaa gcagcggtat tcatcttttc 1020 aaaagcttcg tcaaagctat caaacagctc gtcgaagttt tcaaggaacg tgtcaaagac 1080 ttctgcctca gctccggaaa gaggttcttg atagttatag gagatgtttg caatggcgtt 1140 taccaagtct tgggtagaca gctctccaaa ggttacttct tctttctgga gctctttcaa 1200 agcttcggta tactcgtctt gcacagcttt tggaatgttc caagaagttc caccagactc 1260 gttgacattc ttaattagat tgccatcatc atctcgttct ccaaactctt cgataagctc 1320 catctgctct tctgcataag cttcctgctg cttgttaagc cattttacaa agcgtgtgcg 1380 tttacgactc tcttggcgag ttaggttagg catgttgtaa aagattcgtg ccaagattgt 1440 aatatgagcg tttggaatct tagctgttaa aagttcaggt aaagtcattt aatcatcctc 1500 cataaagtta tatcaatagt atatcataca atcactaaaa tgtcaagcga atagatcttc 1560 caactcttcg gcagagagct cgttagggtc atggaagtct tttcgaccaa cctctgaaac 1620 agccttatca ataaacccat tccacttgaa ttgccgaagc tgcatgtatg aagctgtcgg 1680 aaaccttgca gagcctcccc aatctttaat agctaactcc atccacttct taagaacctc 1740 gtttccgtaa gcctccatat cagactttat gcgaattcta gtaagtttaa cattaagagt 1800 tgatggattc tgcttgaaat gaatcatatt aaggtagtcg agataagtca tgaaagtagt 1860 tgtattccac agctctattg gaagagcctc atagtcgtct gtcctaactt tgttaccttc 1920 tgaatcctta tataacttgt cgtctaatgt tcttgcccaa gccatttaat atacctccat 1980 tcatctaatg gaataatctt atcatatata atggagtctg tcaataggtt aggcgaagcc 2040 tagctgaggg tttcccgaag ctgatgtttt agctttaaag atccttgaac agactctccc 2100 ttaaacccaa ggacttctat cgaagccctg ttcacttcgt tcactaactt cttaacgttc 2160 agtttcactt cactaaggtc aaacccctta aaaccattat acaaatttac aataaatctg 2220 tcaagctata aatggagtaa atctattaat cttaaacaat tcttaataaa ctaacaaaaa 2280 taactccaat cgcttgactt cctccctata ttatggtata cttataaatg taataaagat 2340 taggaggaat aaattatgtc aaaaggatta gatgctattc agcgagttgt tgaacaggaa 2400 gcaaaagtag aacgtgaacc aagtcgattg acttatttga aaaaaggaca gagcattcgt 2460 gtacgcattc cagaggatat tgtagacaac ttgcatgtct ataaagtagt tagcgtgttc 2520 cagaaaatct taccaacgct ttcttacgca gcagagggac gttcagaacg tgacctttac 2580 aacgaagcgt tcgagatcat gcgagaagac tttgcaacag ctaaagctaa cggaactgta 2640 gcggctgacg acaaagaagc ttatcgaaac tccatgattc tacaacctaa accaactatc 2700 ctatttggag taattccatt agcggacttt gtacaaggca agaaagagaa cctttatgaa 2760 gccggacaac cgttgttgtt ggagactaac ttaggtaaga ataatgctaa cattgatgcc 2820 ttaacagcag ctttgacaaa gcctacgaac gctaagaaat ttggtagtcg tgcttttgaa 2880 attacttgca tcgcttctaa ccaatactct tttgcagctt tagatgagga tgagttagag 2940 cctaacgaga agaaagtatt cgaagaaact gctggagtat ctattccaga tgaagtattc 3000 gacggctctc tattcgaaag caatactgaa aaacaattga acgacttacg tttaatcggc 3060 tttgacacta ctcgtttgaa aggcttcgaa aacggtcagc aagaaactgg cacaatcgac 3120 atttctgacg aggatattcc attctaagag gggcgcaagc ctctcctagt cttattagga 3180 ggaactatgg atactattaa aatgactaca gaagagcaac tagcattagt tgatttcatg 3240 gctatctaca atctactagg gcaactagca cagggagact tcgttaacta tgacgacact 3300 gcgacggcta tccgaatcca cgacaacatg cgtgtgattg agtctgtatt ggaacatgcc 3360 gaagactcag tagagttcaa agatgtccgc aagcatttgc taaacctttc agacgtcttg 3420 gtaacacgct ggaaacactt cttacccgaa gctgacctag cagctatcga agagtctacc 3480 gataagttcc gtgcaaaagc tattgagcga cttgtggaga acggactttc agaagaagaa 3540 gctcaattag ctgtaggtaa aattggtctg aacggaggaa actagatggc agttgttgga 3600 gtgatcttac taatcatctt agtagccttt ctggcagctt tggcaggggc tatgtgggtg 3660 ctatgggcaa tcgttcattt ggcttccgtt actattgacg aagctgacga ggagcctttc 3720 aaaaaggtgc tagatttatt agaagatgct attgaaaaat attatcgagc aaaatttggc 3780 aacgaccttg actcagtaga attagtcatg gacgtaacct acaatcatgg agaggatgaa 3840 gactatgagc aagtttagtt atatagccgg ctacctccat ggcaacaatg tttaccagac 3900 gttgtccgag ttttacttag atgacgtgca catagaatcg acaaagtata ttggaggcct 3960 ccctacaaaa gagttgttta ccgcagctct tacggaggct gcccgagaag ctgcttacga 4020 tgttgtggca gaggctgctg acaacttcca caaagacatt gtagtgtatg cgcacatagt 4080 atatcaaggg ctctgcgtag agttccataa agagtataac ttacacgact tcattgactt 4140 cgaagacatg agcgaaacag ttgagaacga ccttgctaac tgggctgtga tgaagtttgg 4200 cacagttatt gcacagcttc cggagatgat tatcaatgga ctatagcaga ctatacgtgg 4260 gcgacaaagt tttgtaccaa ggaactacct gtgctaacac agtgactaag ggaaagactt 4320 acgaagtagt ccgcttgaca actaagccaa agcatggtat cattatagat gattcaggaa 4380 acgataagct cattcagatg ggctatctgt ttgcaaagat tggaggaagc taatgaagta 4440 cgatactaac aaagagatca atgaaacagc cgatgctgct aaacctattc tagaagagtt 4500 agaaattgat cttaaagagg acgagtacgt tatcgtacag ccttatggag atggcaatgc 4560 tattatcatt cgagtggttg aggaagagga tggtagaact attaaagtag aagtatctga 4620 ctcagttgtt gtgctacctg ctaaagatgg tttactggat gtattcgcct aagattggat 4680 gaagatgaat gaagcgatca ttaatcattt gggtagaaga cgttggcaca ttaaagttcg 4740 agaatgtcca agacttttcc gactacaaag aagtaatcaa tttcacttat gatggagtat 4800 ctactaatga gactagggca gcaaccttca acaagtctaa attagttgga tacgccttta 4860 caaaggaggg aaataaacat gttagaaact gttgaaaaac gtatcgctga gcttcttgcg 4920 gagaccggca aagaggttac agacttgcaa gtaactgttg aacatggagt tgagaagcct 4980 gacttcaaag gcgacatgta cgtagcccaa gcaaagcttg atggggaatc tactccatta 5040 gctaagtgga cagttggcga caacttcaaa gacgaccccg atatggtaga gcctttggca 5100 cgaaacctag ttgaccgtat gttggaagac tatggggtgg aagaagagta actagcaatg 5160 agcccactgg aagctcctga cgaggttctt caaaaagagc aagcccaaca gctcacagag 5220 gttgaacggc tgctccagtc atctttttgg gctttgggat ggacgagtct acgagatggc 5280 tcaagtgcac gaaccatata gtagcacgta agtggaagct gttggtaggg cggattgcct 5340 cagtgtgttt ggaaggctga ggaacaagct tctgcaaggg tttatgggag atacgcttcg 5400 gagaaatctt ccagaatatt ggcttagact tagagagtag ctttccgaag agtgaatgag 5460 tcgaaaaaga acggactagg aagccctgcc gaagtccttc gaaacctgtc actagccgtg 5520 aatagtttgt tgactgtctt gtcacagtcc gtgtttctgg aggctgagga tactccccta 5580 tccaaggcct ttggactcac agaaatacct ttaccatttc atttaaccaa ctccttacga 5640 aaacaaatcc aagaagagaa ggacagtctt gccagaggct gtctttttgt ttatataaaa 5700 gcttgacaag aggctgacta agtggtatga taggtttatc aaagttatgg aggttagcta 5760 tgtacaaagt atactatatc acttggaaag gtgcccatga cgttttctgg ctctgtgcaa 5820 acagccaaga agaagctgct tggatagctt ctacgatcca aggtgtcgga gagattgaaa 5880 aaattattaa ggaggagaat tgatatgaaa cttttggaaa acttgaaaca tgaatgcgta 5940 gaggctcagg cagtactccc taattactat gaagatgagc caatgcttac ttgggaatcc 6000 gttgaagaag ctaaccggaa gattgacttc actttaggag aagctgtcag aaactgggca 6060 aatacttttg ctgaccaatt tccagagcag tgggcagagc atgacgagta tgcttatcga 6120 atgctgtttg gagagtctct gatggcattg ccttacgaac tagatggctg cgattgtgat 6180 ttcgaggagg aagaataatg aaggtcaaag agcttgcaga agttatctac ccaaatactt 6240 cactgtacat tgacggtgtt tctaatgcag ctgggaatac ctttatgaaa ctatactcca 6300 tcgagtatct cgttgagcat tatggagaac gtctcgttga agagattgaa acagaacacg 6360 actatgatgc cagcttttta tatattacat tgaaggagga agaatagatg ttagatatgc 6420 gtgtagaaga ttatcgaatt agctcagacg gcaaccaagt aatcgtggaa agggctcgtt 6480 ggacagactc tggagagatt tccatgctaa ctgataagaa gactggcgaa aaatttgagt 6540 cacggtctct tgttggctat taccaaaact tgtcgaaggc tctggtaggt atccaaagag 6600 actgggtact atctaataac ggacattcca tcaaaactat ccaagactat aagaaggcta 6660 tcgacgacat tacaaaagct ttcgaagagt cagtaaactt aggggaggaa ttttaatgga 6720 tgccaaatta agagagttcc atgcagccta ttgtgcagct tacgataagc tttccacagc 6780 tgatgaaaag ctttcagatg ctagaaggta ctcagagctt tatgtaagca gtgtaggtaa 6840 ctttccagaa gcctcactaa ccctgtcagg agattactct gatgatagag tattaaaaat 6900 acctcgcaac ttacttgcag aaactgttgc agagtatatc tcgcttttag cagatgaagt 6960 agacgaagcc gaaggagagt tacaggattt aattaacagc atgaaggagg acgaaagatg 7020 agctttgaag taaaagcttg gttaaatctt aatggagggg atgacataga aatgtctgtg 7080 caggttccca acaatgctac tgacgagcag attgacgagg ctgtcaaaaa tgaaatcatt 7140 gcacatctcg actggggttg ggaagaccct tatgaagagc cttatgagga cacctatcca 7200 tgtggctgtt gcatgtgctg tggttgtagt tgcgattttg agtacgagga catgtggata 7260 gacgaagact gggaggacga gtaaatgcta tttaaagcta aaccaaaagc ttctgcactg 7320 gaatcgacag cctattccta ccattatgga gagtggaatt tccctataga tgctgacgga 7380 tatattcatg gatggtatgt tgatgggtat attgtaggag ctatcgaaga gtctaccgaa 7440 gagtatattg cgccagaatt ctggtgccct attgagaaag acactttgga aattgattta 7500 gaggctatct caaaaattgc tagaggagag gttgaaggga ctgagcacat agataagctt 7560 ttagccctcg atgaacttat tccacatgtt ctttatttag acagatacaa ggaggacgaa 7620 taaatgtgga catggttttg gaagaactct aatacagaga cttacagtaa atacggactc 7680 catggttcat tcattggaga ccctcctcga gtagctgtgg gagatgttta tacaagagta 7740 gatggatatg ctccattaaa ttatattgtc acagctattg acaaagagcg acaattagtt 7800 aaaatggaat taaacgcaag ataatggagg aaatctttaa tggaagaatt atggaagcca 7860 gtggttggct atgagggtaa gtatgaagtt agcagctttg gtagagtcat gagcttgaat 7920 tacagcaagc agggagagcc agctatccga aaactatctt tagataaaga cggttatcta 7980 aacgttaccc tctattctct tggaaaacct aagacgctta aagtccatag attggtggca 8040 caggcattcc ttgaaaacaa tagtaatctt cctgaaataa accacattga tgaaaataag 8100 tcaaacaacc atgtagagaa tcttgagtgg tgctctaggt cttacaatat cagctatggt 8160 caaggtagca tacagagggc actgtctaaa tgtcgtcagg tagaggctgt tgacagctca 8220 gggatccgtc gccatttatt taaaagtacc caagaggcag gaagaaacgg atttacacaa 8280 tcgtcagtgg ctgcttgttg tagacatgag cagtctcatc acaaaggttt tatttggagg 8340 tatattgatg acactagata agatacacct taccaaggaa attcttgtac tcattgacat 8400 acctgagtac ctacagagat atgattgctg ggagaacgct aaattcacag acgagcgact 8460 aatctgctcc agtccttttc gaccggactc ttcgccaagc ttctttgtaa actttaacaa 8520 tgagtttgca gggacttggg gagactctgg tagtggagat tccggaaact ttataaagct 8580 tgtatcacta ctcgacgaaa caggctatga agaagctttg gacaagcttc gggacgagtt 8640 tatgttaggg gcttatgaca ctccacagat aagcgttggg gtaactgctt cccagagtcg 8700 tgatagcttc cggaaagtcc cttggaataa gtctttgtat ctactttccc gaggtatttc 8760 agaagctact caagaagcct atgagacatc tgagggagac gactttataa ggcttccgta 8820 tgttgatgga gtaggagaat ggagagctat taagtatcgt aaaacattct ctaaagactt 8880 cttctatgaa gctggtaaca atcatatcaa agatttggta ttcggccatc gagttattta 8940 caaagagaat ccaacaactc ttgcaatttg cgaagctgag atcgatgcta tgacagctta 9000 tgaaatggga tatgtcggaa taagtcttgg ttcagctaac ttgagcgact ctcagataaa 9060 gcttattcat aagttcggag tagataatat tctgatagct acggacaatg actccaaagg 9120 taacatggct gctgaggata ttcgcaaggc ctttgcaaag actcataacg tttatagggc 9180 aaatcttccg aatggagaag acttgaacgg atactggcag aagaaccact ccaaattaaa 9240 atggataaag ctgtcagaaa gcaacttact aaactttcga aaggtgtggt tttgatgatt 9300 tttaaaacga ttacttccac agatacaatg gggagcgaga ttgaagagaa tatccaacta 9360 acttactcgc cttctaaaaa cagaatccag ttggagctta gttatgaaga ccttgaggag 9420 gatgcttcat actacatgga agattatatt aaactaacta aggaagatgc tttgaaactt 9480 attgaaagct tgcaagagtt agttaaagag atggaggacg aataatgtta aaacgaatat 9540 atagtaggct tgacccagat gagtttatag aattagaaac catatcagga acctacctta 9600 ctgttgaatc aatgtatcat ccaaaccacg actactctgg aaggacagga gaggcgcata 9660 ctttgaacaa ctttgtatca ctagacaaac atgaggtcag aacactcatt ggaagtctgc 9720 aagaaatgct taaagagatg gaggaatcag agtggatata aaagcaactg tatatttaaa 9780 atcaggtgga gatactagca tgataattta tgatactaca ttagaagagc aggataagca 9840 atattcaaaa ttctttgaga agggtattga aaataatatt atatgccacc aaaccaattc 9900 cgaggttata ttcattccag tttctaatat tgcatgtcta agcttaaaag agctgcctaa 9960 ataaactttc tgagaggcct tgacaaggct tcttttttat gctattctta atgagtagaa 10020 aagccactaa aggagttgct aaattgaaga aatcaacctt acttaaaaaa ctgatattag 10080 agactggcaa aactgaggaa caagttaagc aaacgctatc tcacatccac ctccagttat 10140 tcgggctgtc tggagagagt ggcaagttcg gctctgctaa gatacctctg gaatacaatg 10200 acttattctt attcaatagc cctgccaagg atgctcagcc agctacttac gagcttttgg 10260 aaagctatgt taagagtttc cggagatact ttgccaatcc ggaagaggaa tctatcaaga 10320 atctttactt gtggagtcca gagaaaggca acggaaagac ttccacagct gcggcactgc 10380 ttaacgaata tatgttcaca gcatggaaag cttcggtaaa gcttaaggca actattccac 10440 agcctcctgc atactttcta gatgttaaca gcctacagac tttgtataac cgtttcactc 10500 gtcaaggagt ttcctatgac gttacagaag aagcctccag aaaatactat gctgagatgg 10560 atgttgcaaa ggctgctcca atgcttgtgg cagatgacat aggagttcga tcagctacag 10620 aggcgtttcg ggcagacttg catgaaatta tcaattacag aatggttaaa ggacttccga 10680 caatctacac aagcaacctt ccactagttg atatggagca agtctttgat gaacgtcttt 10740 atgataggat gcgtgataag actgttatga ttaggtttga gggagactct aaacgtgggg 10800 tcaagaataa gtccactaag gaggctaaat aatggctaga aacgttacag gagagttgct 10860 actttcaaag gttattaacg agaatgatgt tgcagcactc aaccgccacg gaatatccag 10920 agagatgttt ccggtagctt ccgaaagaga tgcttacgat tttattatac actattcaag 10980 aactaacgag ggtaacgcac ctagctttgc aacagttatt gacaatgttc cggaattcga 11040 ctacattcca aatacggaag actcttttac atatctgtcg aaagagctta agaagaagaa 11100 gttccaagtc gagcaagcta acttcattaa taataagcta tcagaattat ggaatgaagc 11160 tgataaagct aacgatccgg aaggatttgc caacgacatt attaaagctt tcgaggagat 11220 gaaacactcc aacagaatat ctggaaaagc tggccatctt ttagaacacg ctggggactg 11280 gtatttggaa gagttctaca agcgtaagga aggcaagtct atccgctttt ggaagagtca 11340 ttttgaagga cttaacgaca tcatcggagg aggttaccaa gagtctaata tgattacttg 11400 gtatggccgt tctggtagag gtaagtccac gatcacactt atggaaggac ttgaggcagc 11460 ttatcaagga gctaatgtat tattctgggt gcttgagatg cctaagtatg agttcgccag 11520 tcgtgcccta agctttatct cagctaagga aaagcttaag aattcagtta ttgatggagt 11580 tgactacttg gcagggttta gcgtatacga cttgacaaaa gcttctttca aaactgttga 11640 cgaggaacag tcgttcgtag actttgtaat gaagttgaac acagtcttag aaggctcaat 11700 tacaattcgt gctatagatg atgaagactt tattgatcgc tctgtgagag ctttggaaag 11760 agacattgta gagagtgaag cagatgttgt gatcgttgac ccagcttact acatggacta 11820 cgagaagaat acttctaaaa ctaacggagg agatgccgca gctacttcca aagctcttcg 11880 aaagcttgcc ggacgtacaa aagttgttat gcacgttatt acacaggctg aggaagatga 11940 ctccgagaag cgtggcgatg agcgtgagct aaacattcca aagcgtagcc aagttaagaa 12000 gacaaaagcc ttgctggaag atgcagctat tgtactagct ttcgacagtt gtgacggaat 12060 ctttggacta gaagtttcca aaggacgttc cggaggagaa ggagaaggca tagaaggaat 12120 cttcttacct tccattggat atattgaaga gaacagtcaa caggtcgtcg aagagttgtt 12180 tgcagatgat atagaatttt aaggaggtag aaagatggca gctattatac agttttcaga 12240 cggaaccttc cacggcggag ggacagttaa cattaagcca gtaaaagagg cggaacgagc 12300 caagtcatat gttagtgtta aaaaggctaa ggcagctctc cgaagtctta atggtaccta 12360 taaggataga tggaatgagc agatcgaagg agctattgtg tgggaagttg agtatatctt 12420 tgtaaagggg tacaaatatg aaagcagttg agaatctact ttttgtaaca acctttgcca 12480 acaattggtc agtcagtgta gccagagttg atgatggaga gtaccgatgg agcgtacgtt 12540 acaccaaccc aaaaggttac tcagtttaca acatgtatga aacggattcg gaagtctttt 12600 tagagctggc taaagtacag aaatatgagg aggacgaata atggtagaat ttatgttaga 12660 gctatgggct tggagcaagt tttttgaatg ggcttttgga gcagtcgtgg tagtagtttt 12720 cgtagtagct ttgttagtat attggggaat ccattcgtac aagcttcgaa aaataaataa 12780 gaaatagtat tgacaattcc tctgattgat gttatgatta attcataagt tgattggagg 12840 aattttaaat gacatatgca caacgtatga aaacattcta caaggctcat gaaaacgact 12900 tggccttgat tggtaacaaa atagaagcac ataacttcca agtagtctat gacaaagact 12960 ccggagagtt tctgaaagtc cctacgaaag tctctttcgc agcttgcaaa aataaggcat 13020 gcaaactgtg taaggagatt gctgagctag gtaagatagc tgatgaagta gctcatgcca 13080 gaatcattag cagaggctgg gagaaggctt ctatatactc cattgcacgt cttgcggata 13140 ctggaatgaa cttaaatgac attgcagatg ctttagaaac gactccagaa gttatccgag 13200 gactgattaa ggacgacatt gaatctgagg gatggtctat ggaggatgtt gtacgactat 13260 tcagaacgac tttccaagtc tctacaacag ttatgtatga gctaattcca tatactgcgg 13320 aagacgttcg gaaagctatt ttaataaacg gtaaaaagct tactacactg actggtaagc 13380 cactacattt agaggaggaa gaaggatgaa taaataccat atatactacc gtttaattga 13440 gtcacagttc actgattact gcgtagtagt gactaattct attcagtctg caattgacaa 13500 tgctctggag aacataccaa tttatgacca cgttaaatta tccgaaattg atatttgtca 13560 cgttgagaaa gtggaggaat aaagatgaga gagtatagtc aaagagattt atggagtgtg 13620 gttaatggaa aggtagttat tccagaagct attgcagact atttggagag cttccaaagg 13680 ggaggcatct ggactatgaa tgataaagag gatgctgcac gatgtatttg taatgttggt 13740 tggggacatt gggtagaagg atctactgga gaaaaatatg acttcgggga agatcataag 13800 aagtatcata atatgtttgg aggagagact cgttttcata tccttcgggc acttatggac 13860 ggctacgtag tacatgcccc aaaggttgct gtaaggtttg gcaagaagtt tgcaaaatca 13920 tccgaagtag attcagaact cacttcaatg acttatcggt ggacgcctga tcgggaggat 13980 gagtacagct atacgagaag ctatgtacta acgctttcag actaccctga gccatggaat 14040 tacagagatg ctttaatgct acaagaagat tttggagggg agattgttaa gtatggttaa 14100 gaaactgttt gaagtatatg tgacgtatgg taaaggtgac ggcgaagagc ttcgggagag 14160 ctgggtggca gaagatactc cagagaatcg agcagagtac ttggataatc tttgttacag 14220 cgatgagttt gctgactctg agagcaactt cgtagacgga aaaagtaata tcatgcacta 14280 ctactgttat ggtggagatt gggatgatcc aacaggtgga tggttgcagg taagaagtta 14340 tgaggaaaag cgagaagaac ttgccaacga gtatgacaag gaagttaaac ggctcaaaaa 14400 acaattcgga cgtggagagt gattatatga gtagagcatt atctttagta gatattattg 14460 aacagctgcc tgacacgcct gtgggaacac gcttcgaaac agactatgga agcgagcttt 14520 atgtaagtac tcagacagag cctatgccag acagtcaaaa ggttcttaaa tggaagtccg 14580 atgacagggt agtaggtatt accgaagtaa ctgttggaac aacttaccac ttgattccag 14640 actacgttga gattggctgg caggaagctt ttgaaatgat taaggaagct actgaatcat 14700 tccaccaacg gcttactgga gttttccttg agagtgccga cggtttccga gagatttcta 14760 ttatagatga ctttgaggaa gacatttacg ttggagactt catcgactta ttccgtatga 14820 aattctataa atctaataaa taaactttgg gagacctatt gacaggtctc ttttttcgtg 14880 ttatgatagc atagtaaacg aaaggggaca aactgtatga agatctcagt gaatgtgaca 14940 tcagttaccg aagataataa agctaaggaa aagattaaga aagcagctaa ggcaaaggaa 15000 ataccaacta tggaagagtc gtgggagctt atctatagcc gtaagaactc tcctacagac 15060 ttggcaagac tccaaaaggt ggaggaatgg tttaaggaag gaaagattgg ccgagaagct 15120 ggcaaagagt ccaaagcctt taccaaagct gaggcactac gcctttacaa agctatccaa 15180 gaggctgaac gtaaggaaaa gattgaggaa atggctacta aagagtggga aaagtacccc 15240 ctaatctctc aagaagatgc cgaacagtgg gttgataact gtctgaacgc tgacgacgac 15300 tactttgcaa tggactttga aacagtcgga gataacggtg gtaagtataa gtaccgagag 15360 caggtagcag gtttctcact aacctaccga ttcaatggaa agcttgttaa tggctactta 15420 ccaatcctcc attacaaaga ggcagtcgct ggagggtttg ttgaagatcc tcggaacatt 15480 agtaaaggaa tggcttacca attgattgaa aagctattcc acagccctaa gaactccatc 15540 tggcataatg caacgtttga cttaggcttg gcaaaggctg ccctaggcat cgaagcaact 15600 catatgccgc atgatacaat ggttatcatg aagctattga acgagaactt aagcgacgtt 15660 cggacacctg catttccaag cggagtcgga tatcagttga agaaccttgc agaatacttc 15720 ttgaagattc cgtctgatac ttttggagag ctgttcggaa aagatgctaa gtttggctac 15780 gttccattgg atgccgctag atggtatggt gcaaaggata cttacgtagg cttcttgctc 15840 tttgaatggc agatgaacat tcttaataag cctagctttg caaaaattaa gaagtattat 15900 gagcgtattg aacatccatg tatcaaagct acttacatca tggagtcaga gggctttgta 15960 attgatgaga gagaagtagc caaacagcgt gaggaaggct acaagcactt agacgaactc 16020 caagaggcta tcaaggagac tttcggggac gttaacattg gctctccgca gcagttgtct 16080 aagatgttgt actttgaaaa tgattggagc aagtatgtga cacgtgataa gaagtctatc 16140 ctcagcggtc atgtaggctt tgacgaccat tacattagca acaaccgtaa gtttgcttta 16200 gttgaaggca agaagctttt aatcaatcct cgggtagtta acggagagac tattggagac 16260 tctctgccag ccgactcaga tgctctgaaa gccattgcca agcatcacga agaagtccag 16320 ttgattcttg attggaagga tgagagcaag catttatcag cctttgtgga taagattaaa 16380 gacttcatag agcccgacgg aaagcttcac ggagacttca aacaggttgg tacagtaact 16440 ctacgctatg ccgcagctaa cccaaacctc caacagcaac cttacaaggc tcgtaatatg 16500 ttcggcattg gagaagattc gttaatcatg tcggcagact tctcacagca ggagccaagg 16560 ctcatgactc atatgtctaa gtgtaaggct cttattgaag tctatcaaca agctcgtgat 16620 ctatactctg aaatggcttc ggcaatcttt aacaagccta ttgaagagtg tggggatggc 16680 tccatctggc gtaaacgtac caaagtcgtt gtactagcaa ttatgtatgg aatgtctgca 16740 tggtctctgg cagatgcttt gggagtgtct aaggacgaag gtcagaagat gattgacgac 16800 ttcttcaaat cttatccgga agttgaccga tggataaagg ataaccaaga agaggttaag 16860 aagaaccgct atgtggaaac cctttggggg actcgcagac ggtttgtgca tgaggatttc 16920 agcatcctta agaaggcttg gaatgactta accccagagg ataagaagac tcgttcaatg 16980 gttaaccgag cactccgtca gacaactaat ttcaaagtcc aaggaggagc tgcttgccaa 17040 actaaacaag taatcgttgc aatggttccg aagttgcagg agctgtccaa aagacgtggc 17100 aagaagcgtt gctttaatct gcttgcacag gttcacgacg agctactttt caaagttcct 17160 gtagacgtta ctccagagga agttgcagat attgagaacg tcatgattaa cacagttaaa 17220 ttaattgttc caagcaagac tgacattgct attggcaaag tctggggtaa gcttattgat 17280 aaggaggagt ttttcaatga acgaagagat taagcaagag atcgccaaga actttacgaa 17340 ggttaacaat tatattatgg aagcaactaa acgagagatg gctaagacgt gtcaggatgg 17400 tggtttctta gaccactctc tgaccgctct ggtagctaag cacgatattg agcaggaagt 17460 agagaaactt accgaagctt ttgaaagcat cagggcagag catgataaga ttaagaaaca 17520 cgactggatg atgcaagact ttcgagacgg tggtaagcct tctggatatg ctttgaaaga 17580 cttcaagaag ctgcccaaag accaattggc aagggtagcc caactgcaat ccagtatgat 17640 ttatgtaatg gctgactggg gctattacaa cagcagtaag gaagagagac ttaacgagat 17700 tcgcaaagat ttggaggaca tctacaatga agcctaattg gaaagactat ctgagagccg 17760 taggtaagct ggcggttgag ctagggcaag cgctaatcgt tttcgggata ttacttctaa 17820 cgattttctt gattactaag tatatgataa tcttgcccct attttgtctg cttgcagtta 17880 tcgtactatt cggggatgac ttagttagag agtttaagtc taattcccaa atgtttgcag 17940 aagaacgtca cgaaaaggag aatccatctg atgaagccta atttaaagga ctatttgaga 18000 gctgtcggga agtttacctt tatactaata gtgtcagtag ctatatttat agctttttta 18060 ggagttatgt acttatgtat gcgatatgta atacttgccg tgatagtttg tttgggagtg 18120 gctatagcac tagttggcgg attcgtagta tcaacagtct acgatatagc taagggagaa 18180 gctgccgaaa gagtatatgc cagtaccgtt gctacaaact ttggacggtt aactttcgta 18240 gaaactatgg agcatatcaa tgaaatagat tctattgtct acgaggagct gtcaaacttc 18300 actccaaagg aacagattat agtattagac ggcctccgga aatccccaat caaggagttt 18360 aaagttagct gttatgcagt ctacccattt ggctatcttg aaaatattga atggcgcgag 18420 gaacctgaat acattaagac ttacgatcag attatggaag acctccgact tgacattgaa 18480 agagatttgt gatataatgg gacaggtaga ggaggtcgct ttattgaata atgtagaaac 18540 gattcacgag gctccattaa tatacaatgg aatccagtca gacaagtatt tcataagcac 18600 tagaggagtc attcgaaaca tcaaaacgaa taagtgtttg actcctcaag atactggata 18660 cttacatgta cgaatccctc acggagatca gacgattaat gttaggattc acagagctgt 18720 ggcagagact ttcttacccc gaccggaagg ctgtgatgta gtcaatcaca aagatggcaa 18780 caagcagaat aacgacgttt ccaacttaga gtgggtaagc caatcagaaa acgttttgca 18840 cagccttgaa cagcgttcgg gagagattat tctagatgac ttcattgtaa cagtccctgt 18900 aagtggattc cgaacgtatc atattaaagc tgtgtccaaa gaggccgcca aagaagttat 18960 caaaagtggc ggcacaactc cacgctcaca gcattttgaa gagctcatcg gaaaagcaac 19020 tatcatagaa tttggaggat tttaatacat ggctaaaggt ttagcagcag ttaacaaggc 19080 ttccggacag actttggcac agaagatggc aatagacttt gcacaggagc ttgatcgctt 19140 ttgtgccaca ggctttaaca cagacttaca gataactaag caactatatt ctcagtatat 19200 aaacgttctt gacaacaacc cctttgaaga ctttccgaaa ggcgttccat tcttccgttc 19260 aagtggcact ggaaaatgtc ttcgtgagca gactcttcga gcgattgatg ccttagagtt 19320 tactaataat gcagacaagc gttcggtaaa tccttggcag aatcgttggc agaacatcgg 19380 tacagctatt ggagacatgg tgcagatgta tgtcctaatg atggagaagc attatgaacg 19440 acttgttgga gagccttgcc acttccgttt cgaaaggact ccagaaggct acccgatgtt 19500 cgaagagttt tccacgacgt tccaagagtt caagagcggt aagataaact tcattaccgg 19560 aggctctttg gacggcatta tgatttacac tgacccagag actggcaaag agtatcgggt 19620 aggacttgag gttaagtcta agcaaacaac ttatgcagcg actggtcatt ggtctatgaa 19680 ggaagctaac tccaaacacg tatggcaggt tactaactat gctatgctaa aagaccttga 19740 ccagtatctc attgtctatg taaacgcctc tcacaaaggc tggaacatga ctgaggaaga 19800 ctatgccaag tacccagatt tccgagtatt tggagtggag actccagaag agaagaagaa 19860 agaggttcgg aatcgtttct tcacagctgt tgaaatggct cacgaaggag tctttccaaa 19920 gctttcgctg gctgatttcc aattcaatga ctacaagaca gcctgtgccc taagccttac 19980 ttataaggaa ttagaggaac ttaagttaga agcttctact aagtttgaaa aagaggctat 20040 caaagagatt gagaagattc ggggagatgt aaaatgattg aatttgtcaa tgaatttttc 20100 aatgagaacc caaatattac ttggtatatt ataggagtct tcgcaggtta tgggcttaga 20160 agtgtatggg aaaatgtaag gagaggtgta aaatgattga gctgataatt gaagtagcag 20220 cttttgtatt tattgcttgg tactctacca atgtaggaaa acttattgaa agaatgcgag 20280 tatactcgat cctaaataac actgtagata ccctcgatga gatttctgaa aagcctgccc 20340 agtatcgctt aggctattta gcagctttag ataaagttgg acaaggagtg cataacaaat 20400 gacagatacc ttttacacaa ctttcacgat tacctatcta acccctatct ccaatgagtc 20460 tggagacgac attttctatg aaacatatag cttcgaagcc tcagaaggtt ttccggagac 20520 gaagattgag gagatgttaa ctgacctcct tataaatgga gcagtaatca ttggaacaac 20580 cgaggggcta ctgtatttaa acaaccacaa catcgcttct atcatggttc ataaggagga 20640 agattgatgc gtttcatggc ttttgacatc tcatctgttt caacaggtgt agcagtatta 20700 gaccaagagg ctaacggtaa tcttacgtta gtctttacca caaatattat tacaaactcc 20760 aaggataaga ctgggaagcg ccttcgaata ttcgccgaag agatgacagg gcttctcaat 20820 gagtttaaac cagactttgt aattaaggag acgacaatct gtcggatggc tactcaattt 20880 attaacatga agttcttcgc agccttcgaa ctagtcttgg aattagaagg gtacccacgc 20940 tactacgagt atggcccgac gactgttaag aaggttgtcg caggctctgg gaagtcctct 21000 aaagcagacg tagcagaggc tatccaaatc tacacagacg ttgatgtatc agatatgaca 21060 acagatgaaa ccgatgctat tggaattgct cttactcata ttggaaagac ttctatgctc 21120 attccaaaag ctgagatcat ggctgctaaa gagtttgatg aacagcagca ggaagctatg 21180 gaggctgtcg gagatgatgt ttaaaatcca atatacagta gctttcatcc tattagtcat 21240 tgtggagctt ttgcaatact tggtatacat cctagtagca cctgttgcaa cattcgtgca 21300 agagctctgg gagagccttt cagcatttcc ttttagagct atcagattcg cttggaaaag 21360 atattgcaca gccatgaaaa caggagaact tccatcacag acaaggagga caattagttg 21420 attaaaatag cattagcagg aactgcccga gcagggaagg atacatttgc taacgtcttg 21480 gaacaagagc tttccaagca gggttatgaa gttattcgag tagcttttgc agactactta 21540 aaagaaatct accagcaatt ctttggtcat ttagtcaaca acgagaagcc tcgggatgct 21600 tacgtaaccc ttggaaatgc ttttcgggag attgatataa acttctggat tcgtccagta 21660 gaggccatta gagattattt ggagaataca gagggcttcg gaaagcctgt agcaatgatt 21720 atcactgaca cacgttactt taacgaagct ctctgggcta gtcaagaagg cttcttagta 21780 gtcaaggtag atgctgaccc actaattcgc caagctcgtg cagaagcttt gggagagact 21840 ttgaaattag ataatgaagg ggattctgag gttgatctca ttcagccgga cttaactatt 21900 ctaaataatg gagaagctga tttccaagct atgccagcag ttgccagagc agctattgaa 21960 gagtataaag cgaggtttgg gaaggttgat tagatgccat tgtataatga atgtggtttt 22020 tacagagcta ttacagaagc tgagacagca gggcagtgtg ccttgcatct caaacgcttt 22080 gtgacagttg tcctaagacg tagtaaactt ccagcagaag tcagagggct gtttgtagaa 22140 gaggcctacg agctgtttca taagctttgg ggggaagagg ttccagatac cttagctcat 22200 gccttaagca ccttctacat gcaggacgat actactggag ggctttctgg agacaataag 22260 tatgctaagt gtagcagctt tgagtatagt ttctactctt atcgaaaaga gaagcggata 22320 gccaccgaag actatttcct agaatcggaa tttagtccta tgatagagaa ctccaaagtc 22380 tatggagact acatggttga ccaagactac tggatttggc ttgaagaagt tattgacaga 22440 agcaaccttc gacctgatga agaatacgtc ttccggaaga atgttttgga aggcatctcc 22500 ctcagaaagt tggaaggata caacggactt tccaaaagca ctcttggcag acgtttgaaa 22560 gatgctcgca agaagtttac caaagcagtt acaaagtatg gtaaagaggc aggataaccc 22620 ctgtcttttt attttgcaaa aactgttgac aggtttcaaa agtcatggta tgattaattc 22680 ataagttaac agagaggatg ttgaatatga cttttaaagt aggcgataaa gtaagatgta 22740 ttcgagggag tttatttaat gagattcaag tagacgaagt atatactgtt agtaaagtaa 22800 ccacttccga tacaggcaag gagttgattg aactagaaga ggattttaat ggagcttggc 22860 ttgctgaaag attcgtgatt cactatggag aagataattc tccagacagc tttaatatta 22920 atctgggaat agtttatgga atcctttata acagtattaa agatactgac gaagacttgt 22980 ggatgattgc agaaaatatt gcagaagctt tggggaagga aggttggaaa gcatgatgaa 23040 gcggtatgaa gtaatctatt acctagactt tgaaagcact ccacgaagtt atgtagtcct 23100 agcccacagc cctgaagaag ctgtcggaaa gacttgttgg agagaacgtg ggaaagctgt 23160 ccgagtagat attgtgaatg aagtttaagg aggaattgga atgagttacg cagacaacct 23220 tgcgaatact ttctggaaga atgttgacac tcttcggaaa gcttatggaa tgacgtggaa 23280 cgacatatat gagagtggac tagcttcaaa aatgtttaaa gctaagaccc ctccaactat 23340 gaagcggatg gcctctattg cagagattct tcacacgact gtaccagagc tgttggacga 23400 cagccttcat gaaactccta ctgagcatct ttatattgta actattggag aatgggctct 23460 gacacgctta acaaaaggcc aagcaacgtt tacaaagaat tgggcaacag agcctctggc 23520 gtttttcaga gactttgatg atgcttataa tgctactaaa gagttccctg ctgcggaggt 23580 ggaagtgtgg agttaagtgt ttttaccaaa gaagagttgg atgttattag ggctttggta 23640 cagcgttcta tagatcatgc agtagctgcg agaattcctt tggaaggatc ggctctgtcg 23700 ccacagcttt tgtcagagct gtacgcaact aataccaaaa cgctattgac aatgtattcc 23760 attagtagta aaatagactt attgaaaggg gaggaataaa tatggaacag attattttaa 23820 agagtgcagg aggattctcc acaatacagg ttgaccaatt aactaaagga aaatccgtag 23880 atattactct cagagatagt gagaaatcta aatgtggagt ctataattgg gaggaagtca 23940 aacagttcgt ccgagagcta tcagaactcc ttggactaac tattacaaaa gatatgtcca 24000 aagaagagcc gtatattctt ccggacgagc ttgtggaaaa gcttaaatat gagcttagca 24060 agaatcagcc agactcagat caatttatct gggaagcttg tacagaagat tctgatacag 24120 ttattggcaa ctgggtacaa gaaacggaca acgccattga acagctatgg agcatcttcc 24180 aaggacatcc ctttgaggct gagaagtttt atgttttaag agacagtgat gacgactatt 24240 tgagaagcta tacaatagca tcggatggca ctgctgaggg agaccttact atgtatccta 24300 gcaatgctgt taaattttct gctaaagaag atgcagaagc tgtgcaaagg cttttgaaag 24360 actaccgctt caatattgga cggtattagg aggagatatt atgcaaagat atgtacgttt 24420 gttgaataat ggagggtacc cagatattga ccagtatgtc ggaaaagttt tcccagttcc 24480 ttgggatagt tacaacctag ttgaggtaaa acttccggat gaggtgtcac gattttttag 24540 catatctgat ggagaggccg agtacgtaga acatccagaa gcttccctag acgttgcttt 24600 aagtaatttt atggagcagt cggatgagct tatcagagcc cttgaagaga cccaagcagt 24660 gttaaaggcc gctcagcagg ggacaaagga gcctaaagta ggagattttg taaagattaa 24720 gtccaaggat aatttggaga tatctaccaa actatataca agtcgttgtg gctacgttgg 24780 aaagattgta aaggtaagta acagcctagc agatagtcgt aaagtattta ctgtaaaatt 24840 tccacaagct tctttctctt ttctggagtt cgacctcgat cactatgagg caaaatttta 24900 cgaaagcgag tttacagttg tgccagaagg tacggaaggc ttacagggag tccagccatc 24960 tattggagta tttggaataa agtcggatct aaaaactcta acaaatattc ccgaagaatg 25020 tgttagtatg acaggagaat tttacacaga atttttggat ggaaatgtaa caattacaga 25080 ataatttttt tgacagttgc cgaagggtag ctgtctttta tttttgccaa gaaatttgga 25140 ggcagatttt tcaaaatatt tttctaagtt aagggatatt tttaaaatta tttttctagg 25200 aatggagtaa atttttaaaa attttttcct ttaatttttc aaattatttc aataaactct 25260 taaaatagcg ctataacagc tttttaacgt cgtcagagga acattctaag cacgtttcag 25320 atcaaagatt gggcaatcat ccattaaaaa tactctgaca gcctttcaat tagcctccat 25380 aataaaaact taccacgtct tggcaaagct tttgccacag ctgtcaataa gactccatca 25440 attagcacaa agctattcaa aaagcttata ttcatcctca aaataacatt taactaattg 25500 agttccccag aattttataa cagtcccccg ggatttttaa taaaaatcac ttaaaacatc 25560 atgacaggcg tacgaggttt ccggcagctg tccacaggct gcaccccggg atttttaaca 25620 gttttcactt aaaacgtcat agcatataca caacattatc aaggcttttc cacagctttt 25680 aggcttcttt tggacgactt ttgaacaaga tcaggaagaa gtctcgctga aagttttcta 25740 ctatataagg cgactttttt gacagctttc gaaaaataaa ataaaaaact ttaggtaaag 25800 ctattgcaat ttaaaaaacg ccgtggtata ttggtatcaa gttaagagaa aggaagttga 25860 aaaacatgaa agaaagaatc tttaattttg aatatttgac acaagaggag aacgaagcgg 25920 taactaatca ctatcgatgg tgtaaaaaag caatgaatag aaatttgata acgtctagcg 25980 aagctcagtt tatatttact gaaaaaatga tcgaagatta cagggaaaaa gcctttggaa 26040 tttgtacgaa cgttccaatg tttaccgagg aggtagcaaa atgacttata acatttatac 26100 aaacgacaat ttttatgcta cttgtggaag tctgacggct gtttatagtc ttgtggctag 26160 tcttgaaaag tatatttcaa aggataaaat aaaagtgttg acagtcattt gagaatttga 26220 taagcttatg acgagatcaa gaaaggatgt gggaaaatgg ttgtttcatg gttgattcta 26280 gcgcctgtat gtgtcgtggc aagcgcactt gcttttgttg cttggttaga tgattaaaaa 26340 gtttttacaa aacactttac aaacatattt caaagcagca ttataagact acaaataaaa 26400 ttattggagg aattacaaaa tgaacgaaca aaaacattat atcacagtcg gagaaatctt 26460 agaaactatg gaagaaagct ttgggctgtc tgattgggaa actgtcaaaa aggaacttga 26520 aacaatgcaa agccctatca attttacagg aaaaacagcg ccaactttga gcaaagatca 26580 ctttgggcgt atctctttgt taagcttttt caatgaattg gaatatgctg gcgaatggtt 26640 aaccgttgac gaattgaaag actatttcaa cgaattagaa aacgattggg gaggcgtttc 26700 ttggtatgaa tatggtgccg acaatactta caattattgt ggctaccttg aaagagattt 26760 aaactttatt atctatgaga atgattgcac agaagaaact ctagttttct ttgctgtcca 26820 tattggcata gacgtgcgag caggctatac aaaatacttt gcgatgaaat tcgacaacct 26880 ttacaaattt caagaaaagc tgtctgaacg ctttgagctt gctttcttag aatataagga 26940 cagcgacgga gacattcaag gggtatccct atatggttca gctacgagtg aattcattaa 27000 cggttatttc agatatgatg ataaagactt cgaagaatgt ctcgacatat acgacaaaga 27060 aacagctatc gaaagcctaa ccgagtttat gaaagagcaa gaaattgatt tcattgaggg 27120 atctttggag gttgtcgact aatggttaaa aacgaatata aaagcatgta tgaagccgaa 27180 aaagagaagc aagcaaatag cctcgtgaat aagtctttca aacgaggctt cacaactatt 27240 aacaacttga aacgttcttt agttttagca aagacttcgc aagaagcatt acaaggcttg 27300 tcaacagatt caaaaagcta ttccgaaact atgacgatgc tcgaggacaa tcttttgaaa 27360 gcttcgtcac ttatgttgag tgtagagcta gattttagaa acattcatca taattttaag 27420 aaagggagtg aatgacttgc tacctatctt gtgggcggtt tttggtatag ctgtctggac 27480 tactcttaaa aaagcttgcc aaaaactttc tgactactta gaaaagcgaa aggataaaca 27540 atttcaaaaa agacttgaaa aacaatttaa gaaagcttat aataaagtca caggcagagg 27600 cttgctcgaa acatatcgaa gagggaagct atccataaat aacctagcgt tacttttgga 27660 ggctgtcaaa gaagttgatc cattactcta tgacgacgtt gtgagaaagc tttctgatat 27720 gattaggaaa gaagaaataa ggaaaggact tgcaaagcct agtgagctga tagagacacc 27780 taattttttt ggagacgatt cagatgatga tttgataaca cttgataaag atttatagaa 27840 aggagattgc gaaatgttag aatcgtttat tttcatagct gttgcattaa tcggaggtag 27900 cttttgcaca atccgcgcga tgaaacaatt agacgaaatt acaaaagaag cagaaagttt 27960 taaataaact attgaaattg taaaaaagct atgctacact atagaaaaga aattgaaagg 28020 atgataaaaa tgaaattctc acaaaaacat tacgctatgg tggaggaaag cattggcgct 28080 tttgaccgtg caaaacttat acaatataaa agtcagttgt cagaaaaggt aaaaagaaaa 28140 gaaatagtgg taaacagttt tgaagttaga tttatttttg acgtttatta tgcttgtgta 28200 ccgctaccaa ttagactgca aatcagtgaa gaaggaaatt acaaggataa ccatattaaa 28260 accgccgtaa aaacggcttt acagaaatta gatatcttat aacttttcaa tagaactata 28320 aaacttttgg aggcatacaa aatgaaacta aaaaacttta caattacaat gttaacaatt 28380 atcacagttt tgaatataac ttttctcata ggtaaaaaag cttatgagaa aggctatcaa 28440 gaagcttcgg aagctaacaa agtcaacaat gagcttctcg cagaagcaga agatactatc 28500 gaaagcaacc gcaacacgat cgcagatctc aataaaaagc tagactctta tgcaactatc 28560 aaagcagact ttgtcattgt tgaaagcgac acgaaaaagt tgtacattta tccgatcgac 28620 aatgataaga aaactattca gactttcaaa gttgacgagg gaataggcat agaagctgtc 28680 aacaaataat cgaacagatt tagaaaggct acttcataat tggagtagct ttttaattat 28740 taagaaaagg ttaagaatct atctgttatc tatcattttg aaagctatca gaaaagctga 28800 taaataagct tgtagatatc ttgtctatac aagttgtacg ttatgcttca gagagcgtgg 28860 gacttaactt ttttaaaagg gtatctgtta tgtaagtaac agattataat aagctattac 28920 agaagctact ccattatcta ataagaagca tacttctaga agcctttgca aaagcttccc 28980 aaggctttcc aaagcttagg caagtaacta tcaatagctt atcctaaagc tatcagaaag 29040 cctgtcaaga agcttatcct aacaactaat taaatagata aaagagaagt tgcaccattg 29100 attggagtag cttcttttta tatcctctta aatagctcac gagaagctct ctcagacgtt 29160 tcattataga atggtaacct actattagcc tatcatttgg ggagcgtaga tgagaatata 29220 caaggcatat ttgagaagcc tattctagca actattatag gcgttactca agaagctatt 29280 ctggaacgtg gttcacaact atccgagtag ctgttacgct aactgtttgt gagtctttct 29340 gatcgcctga taatagctta taatggagcg tgttgcatgg cgttcgatag gctgtcaagc 29400 accttgccac agctgtcaga ctacagtcaa tcagtcaaac ataaacgtaa aacctatata 29460 gagacgtcga ccaactgccg accagctgtt gatagtctta tggagtggct tctgtaggct 29520 atcgaacggc tgttcgcata tctattgatc tagtttacat aatgtgtatt atacaaagtt 29580 gacaagacac attgactcaa ctgttcgaca gtctcgacac acgttgaccg acgaccgacc 29640 gacgagacac acgacagact cacgaacagc tgacgtaata ggctatctga caggcttccc 29700 aaggcgtgcc agctacgttg accccagcaa gggagggggt cttgccacag ctgaccgaag 29760 gcgcgcgcac tgttagcctc tgacaacttt tgcaagtttc cgtgtgaggc tgtccgattt 29820 attttttctg gagtttccta ataggctgtc cgacagctgc cgacagactc cgaaaacggc 29880 tggccaattt tattttttgc agttttccta ataaggcttc cgacagctgt tacaatcaca 29940 cgcacgataa gctgtttggt tagtttatcc ataactccat acagaacaaa ataagccgcc 30000 ctccgacaag ctgtcaaaag gtggctcata taagtattat ggaggcttag gcaaagctcc 30060 agtagaggcc tttgtgagtc ttttggcgac cgttacagca atctcttata cgtcgaggga 30120 taaacccttt attaccagcc tctgtgacgc ttttgaaggt gtgaactatg tttccttctg 30180 aatcctttgc aataactggt ttggactgct tttttgccct ccgttgccta gccgttccgt 30240 gtaagttatt ataccgatag gtacaccatt cgaggttgat gacacagttg ttaagcttat 30300 cttcgtctat gtgattgact attggaaagt tgttagggtt tgggcaaaaa gtctctgcaa 30360 taagcctgtg cattttatgc ggcatcctat tcatatatac aaccttatat cctccaatgt 30420 tcacgtaacc taagcgctcc cttaatttac catatctgtc aaatgaagca attctcccag 30480 aggggtgtgc catagctgtt gagaggctag ggataggctt ccaaccagat aaatcttcaa 30540 taattgctcc ttgctttgag gggggctttc tggaagctac tgaatgtctt atgttatggc 30600 tttgggagca aatttccaaa ttcattacat tggcgtttgt tttatcttcg ttaagatggt 30660 taacaaccca gccctctgga atatctccta taaaagcttg ggcgacagct ctgtggatca 30720 acaaacatcg tcctatgccg cttaccttga atgatggata accccctaca ggagtccctt 30780 tcaaaaatct cccaagtctc cccttaacct ttccttccat attaacaaaa tacccctcag 30840 ccccttcgac aggcttccaa atagttgggt cataaactcc ttcaaatcta attggcttca 30900 aataactttc ctcctacaat ctattatctt acttgatatc aacgttaagc tgcttataca 30960 gcttcctacc ttctccaaaa ttcttaagta catatccctc acgctggagg aacctcttat 31020 aaatgcgacc tctccgattg tcctcccagt ctacttaaat gtacgtcggc aggctgtggc 31080 aaagttcttc cttggcatac tcctcaaact ccctaagctt tctaatagcc cacacaaaag 31140 gatatacacc gtctttccct gtagatttca aagtgttatc agaaatctgc ttccgcttat 31200 ggaatacatt tagaaataca ttagctactc caatattctc taaatcatat agctgaaact 31260 ctattctaac agtcatgcca cttggtaacc tttcttggtc aactattact tttccatccg 31320 gagtattttg aaaagtgaat gccatacttc ccctcctata ctcatcaaag ccgccttccc 31380 acagctttgg aaagcgactc tattagctta tttatattta gtgtccagca ggtttatgat 31440 agctcttact aaactcttcc gctgcttttt agctgggctc tcctgcatca atgcccctac 31500 cttccacgat ggagtgccat gttctgcacg agcttcttca aagcgtttag cagttgattc 31560 caaatccttt tccgtagccc tgtcagcata ctcttggaga gtcttgtcag cagctttgca 31620 gagaacttct tcacgagcct tttcaatcag ctgcttctcc gtacgaagcc ttacaattct 31680 atcctctagt aggtaaatat cactaactat atctgataga actacctctg gagctactcc 31740 ctcaagtttg tagtaaagct ttcgcaagac ttttcgatca tactttaagt tttcaatctc 31800 tcgttcaata gctgctcggc gttcttcagt catctattac caccatccca tgtctggctg 31860 cttccaacag ccgttcttgt tcttgttgtt gctgttctgg agtctctacc cagaacttta 31920 tcacgtggtc taggttgtag ccgtccaaga accttggctt ccactgttca aaagctgcca 31980 tattagttct catatctttg gcatcgcctt ctcggaacac ttctacagtg ccgtcagaaa 32040 gctttaccat gaatctgtgc ttaaattttc catcttctag cataagataa ttcctccagt 32100 atcctcatag tctatctcaa tgtcgctgat ggagtctagg taaatatctg ctgagccaga 32160 tgtcctatat atgctgatag gtgtatccac aggatagtcc agtagcttct ccactagctc 32220 tccaatagtt ccggcaggaa gctttgtgaa tgactgttcc aagacgtctg catctaatct 32280 atcactccat gggtcgagta aacctccaat gtcgtagcaa ttagtttccg aatctactga 32340 taggactttg taaaggtctc cttcataatc taacagtaag tctcctttgg agtatttcat 32400 tggtctattt accatagagt cacttcccct tcctcaaatt tactaattat ttctacatct 32460 tttacgtcaa ctttccattc attagtgttc cattggcaaa tactaacact gtcagtagga 32520 tcgtgcttgg acagctcatg gataagccat gcaacagttc ctataggagc tttcctccat 32580 tcgtcctcta ccaccgaagc atacaaccac atgtaaaggt cttcgccata ctttaggtaa 32640 tacttatctc cccaagaatc ggttgagcgt gacaccactt ttacaattct cattggggca 32700 tctaaatctc tccctgcatc tactaaaaca tctcctactt caaacttcat ttcaattcct 32760 cctcacagat ttttacaatg tgttcacaca gctcttgggg tattctggat ctatcgacac 32820 tccctttgat accttgggta cctgtcttag agccacgagg ggcggctatc tgaccatcta 32880 tgatagcttt tccttcgtcg tcgtgataca gggcttcgat ttgaagtctg ttgatacgtc 32940 gttcgataag ctgtgggaag acttccgaaa ggactgtaat cattttgcca ccacctttac 33000 gtcatctgtt acatcaacaa tgtcaaagtt ggcatttacc tcgttactta gaccacttcg 33060 gctactggtg tcaacattag ttagattaag actgcttaga taggctcctc ttccggactc 33120 caactcaaca aggtcgtagt gatattctcc aaaagattca caatcaacac atagatatag 33180 tttgtcatta attaaataaa cacgtccaat cattaatgta acatttcctg ctccggctgg 33240 ttgataatct acttccataa atcttcctcc tagtctttgg aatacttttt gatatgatct 33300 ggtctaaagc cactccactc catgccatca cttacgataa cgactgggaa gctgctgtgg 33360 ccacgactct ttaagaattg taacatctct gcatcagttt cgtcaactac tatttcctca 33420 aattctgtac cctgctttgc aaaggctaac ttagtttgtc tgcaagctgc acagaaggtt 33480 cttttcgaat aaactttaat catgctgtac atagtcctcc atattgtaaa aatagtttct 33540 taatagcttt tcggaattct ttcattttgg cacctccatt actctaatga tatgtctata 33600 acagcccaaa taataaacca tactaaacaa aaacctatta agaatagtat aagggtttcg 33660 aaggatactc ctgcgtagta tattaacaca gttccaagta taaatatcac aacagttgat 33720 accaagctaa ttaaaatgct aagtccattc tcactcaaaa ctcatcccat ccttccacat 33780 aagcatattc ctcttctggc aagggcttct tagttctcaa ttaattcacc tcagcctttc 33840 tcagctccac taaagcagtt gtatcgccgc cactcatgac attccaatca gatgaactaa 33900 acgctccata gaacactatt agaatttcat aggaattggc aagctctgta agttgttcgt 33960 cgatacctgt atacttgaga tgaccgtctt catcatactt agtgaaccct tgcagctctc 34020 tccattctgt caactactcc acctccagta tcttggacat ccgtgcaata gcttcctcag 34080 cctgtttgcc agactcttga atcttattat ccaatcgttc ctccaaagca tctcgcacag 34140 cttccggaag gtatctgtcc aatgacaaat ccgccatctg cttacgagct gtggtcatgt 34200 ttgataaagc agctaggtac acatccaagt taatatctag tgaaatatct aggacagttt 34260 tgtgagtaac ttgtggaatg aatggtagat cagtctcttc gtcaactaat tgcagttcgt 34320 ctgcataaaa ccagataact tctccctgct ccaatccaac catgacattg gggtcttcta 34380 cccttctatc cgggatcact gttctaacct ctccaatagc tcctatagga atatctggag 34440 atacaattgt atatctttcc gataagtctt ggaaatacct tactttgtcg cctgctttaa 34500 attctgtcat aaataccctc ctaatgtttt actaagttgt ttgtctagcc tagaaatctt 34560 tctagctact gttgatttag gtactcctaa agacttctca atttctctaa cactagactc 34620 tcgaatgtac ctttcaacga atagtgacaa gctttcttta tcataccatg gaagtatctc 34680 agttgtcaag taaatggcat caatccatcc atcttctaag gaaacttcca cagctagatg 34740 gtcaagaagc cccatcggaa actcatgggc atacttctca gagggtgtct tcattctacg 34800 gtgcttacga aagctataga agctatactc aaaactactg cacttagcgt atttgttatc 34860 tcctccaata gatcctaccg tatcgtttgc caaagctaat agagataccc actctgagag 34920 ggattctgga ggctccccaa atcgcagttt ataggatgat ataatttgct cagcccatag 34980 aaagttttct ttatcagttc ctttatttct caataggtac tttatgagcc gaataccctc 35040 ttggacggct ttacctttat ttacagctct ctgaaaattc tcatacagca taataagcct 35100 cctaaaattg tctgagagct gttctacgcc acttacacct aatcatccaa gaagataata 35160 aaagtctcct cagacggctg tcaacgactc ataggcgtat tgtagcttcc ttagctctat 35220 gaatctatct taccacgtct ttggagactt gtcaatagct ttttgaaatt aatttaaact 35280 ccattgcaaa accttccttt ccttttccca gtttcggata agctttctaa aggcttttgc 35340 aaggcagctt cttggagtac cgtcggtatc agcgaccgac agcgctaaaa ccttttctct 35400 aaaagcatta tagcataatt taaaaatctt gtcaagtgat tgactccatt atattaaaat 35460 actctcataa tactccaatg ggacgtctcc agcttctaaa ggggctatcg aatgaggact 35520 tattaatctg ttggaaggag gagacagatg gctcttaaaa ttcaaggaaa agaagtcgga 35580 gagcgacagc agcagtacat gacttcctca cagactccag actactatga tggagtagat 35640 ttaacaaccc ttaagccaaa gatgaaacgc tttgcacagc attatgtagc tacggtaaac 35700 attgctgaaa gctgtaggtc tgtaggctac aatgaatctt ctgggcaccg cttattaaag 35760 cgagctgatg taaaagcgta tatccaatgg ctgattactg agcagtccaa cgctgacatc 35820 atgactgcta cagaagtctt ggagcatctt acaaagattg ctaagcgaga tggctatgac 35880 gagattgtca cagctaaagg ggataagatt caagcaagga tttctacaaa agaccagctg 35940 accgccttac aacaactagc taaattccat gacttgctaa ctccagacgt acaagtcaat 36000 aatgaattaa acatcatagt cgatatatct gagccggaag acgacgaaga agaaattaag 36060 caggccgaag cagttgagga cgatgctttg gaagcagact tcgaagagac cgacgaagaa 36120 ctagactatg gctttctgga aaactactaa aggaagggag aaatccttat ggaaaagctt 36180 ccgactcccc ttcggaaagt catttcaata ctctatttga aatggcacgg cataggacta 36240 tccgtagtca gtattctgta tggcgtaagg ctatacttaa acatagacac acttaatcat 36300 gaggctttat acgaccgcat ctccagtctt tttgatctac aacttatatc agctttcttt 36360 gtaacagctg gatttatcaa acttcttggt atcatcctta acagaaacag acttcgtata 36420 gcaggagtaa cctctttagc agttctttgg tctgttatgg gagtaaccta tctgcctacc 36480 cctaatacga ttgctattct ggctattgga tgtgcttgga cagcctatgg agttctcatt 36540 cgggaggact ttaaatgaac ttccagcact gggatgtact aatcactggt gtattagcct 36600 ttgtaactgc ttgggtaggc aaaaacttag acttcaaagg gctagtcaga aagactgaga 36660 tagagaatcg tgacgagatt tacactagct ggaaagagat gtacgagact aaggcagccg 36720 atcacaacga gctaaaagct gagtacaact ctgttcgaca aactgttttc gacttagagg 36780 aaaagtttag ccagttaaaa tttgagatgg ctgacttgaa gcgttccatg caagagaagg 36840 aagacggcta cttgctacag atttctcagc ttgaggaacg tgttgacgaa cttgaggaag 36900 aaaacgcctc tctgaaagaa gagttagaaa cctttaaagg aggtggtaaa tttgaacaac 36960 actgaaatca tcatgaccgt tgcagtcggc atcggggcag ttatgacagg cttaatgaat 37020 atgattaaat ctcaagagta cattccagct cggtacattc ctttggcagc tatcgtctta 37080 ggcgttatcg ttggagtagc cggaggtatg attgtatttg atgtcgaacc agttatcgga 37140 gcagttgcag gacttattgc agggctttcg tctgtaggct tctacgagac tggcaagtct 37200 gttaacaatg ctatcaacaa ataatcaaga agccctacgg aaaacctctg tggggctttt 37260 atctacttta ggaggacact atggcaaacg ataataaaac aattccatta aaacttacag 37320 tccctccaag aatctttaac gaggcttacc ttccatactt atataataag cctaatggta 37380 agtatcgtac aatggttttc tacggaggag caggttctgg taagtctaag tttgtggttc 37440 agaatacgat tctaaaaggc ttagcaagta agcgtaagtt tctagtcaca cgtaaagttg 37500 ataatacgat tcgggactcc atcttccaag aatacaagac atgtctacag gagtttggca 37560 tctacgacat atgtgatgta aaggcttcat acatgactat taaactacct aatggaacag 37620 agtacatatt taaagggatg gaagacccag agcgtatcaa atctatttcc ggtatctctg 37680 acatagttat ggaggaagct actgagttca ctttggacga ctactcacag cttcaactac 37740 ggctgcgtaa caaggctgcc ggaaacaacc aagtatttat tatgtataac cctgcttcaa 37800 aagataactg ggtctaccac atgtttcata acccagctaa gaaacgtcca gagaattgca 37860 aagttattag tacaacttac aaagacaatc gattccttcc tagatcatac atcaagcagt 37920 tagaggacat gaagaatact aacccagtat actacgaaat ctacgctctt ggaaagtttg 37980 ccagccttgg taaacgcatt tatacaaact ggacaagaca gcggctagac ttgcgtaagc 38040 ttttgagaga ccgctggaaa cctaaatggg gactcgactt cgggtttacc aatgacccta 38100 ccgtactact ttccattatg atcgatgaat cttctagatg tctttacatc tatgatgaaa 38160 tgtatcaaac aggcctcttg aacaaggaca tcttcgaaga gattaagaag cgtaagatag 38220 tccacaatga aatctttgca gatagcgctg agccaaagtc tattgaagag cttcggaggc 38280 ttggggcacg acgtattaaa ccttcacgaa aagggaagga cagcatcttg catggtatcc 38340 aatatctgca aggctacaca atcgttgttg atccacgctg tgtaaggact atctcagagc 38400 tggagaatta tgagtggcaa cctaacaaac atcttaagga cgagtacctt aacaaacctc 38460 gtgccaatgg ctttgaccac tgtatggatg ctcttcggta tgctgtatca gacatgattc 38520 caagaaacaa agtaaggtct atcagtaagg ctgctttcgg actgtaggac agttatacaa 38580 aagtctgggg ctgtaccttt gaagacaatt aaggaggact atcacatggc tattccaaat 38640 aaccaactgt ctgctggaga catttataca gtcgctgata accgtaagca ctatataacc 38700 agagacttta caacagacga cttaatcaat gctgctgaac tccactatgg gagagtaggt 38760 agctaccagc ttttgtatga ctattacaaa ggcatgcacc acgctattct aaacagaacg 38820 tttgacgata agacaaagcc taataataaa gtcgttcaca acttccctaa actgttagta 38880 gatacagcag cctcttactt agctggggaa ccaattactt taaaaggcga cgagacaact 38940 attgatgcaa tgcttccaat tcttaataag aatgatttcc atgacgttga caatgagttg 39000 gttaagcttt ccggaatctt tggccatgcg tttgaaatcc attacctaga ccgcaacgga 39060 gactatcgta tcaaagcaat ttctccaatg aacatggtac tatgctattc gatggacttg 39120 gataatgagc ctttggcagc aatctattat aacacggtgt accaaagtgc tactagagct 39180 gtgtatcgaa cctatgaagt ctatactaaa gataagatta ttaaattcga aacagagact 39240 ttggaagatg gaactaaaaa caagcctatc ccagaaactt ttcccaatct actaggaaag 39300 tttaatgtat ttgaggtcat tgctaatgaa gaacgtctgg gagactttga agctcagatt 39360 ccattaattg atgcttacaa cttagctgtg tcagactctg taaatgacat taactatttg 39420 aacgatgcct acctatggtt agctggattt gacattggag aagacgaaaa cggtaactct 39480 gagttggata agatgaaaaa caaccgtgtc atggttaccg aagaaggcgg aaaggctgag 39540 tggctagtca agaacattaa tgatactcat attgagaaca tcaaagacag agctgagcgt 39600 aacatcttta gtctttctca aactccagac ttgacttcta aagacttcaa tgcagctact 39660 ggaacagcta tgaaagctgc tacacaacca ttggagaata agtcagcagt tcgtgagtct 39720 aagcttcgca aagtattccg ccaacgttat gaaatcatct gccactactt gactaatttg 39780 aaaggtgcta aagatcttaa accagagaaa gtggaaccag tctttgtacg taaccttcca 39840 caatcattct cagagttggc agatatggct gttaagcttc gtgacattct accagacgaa 39900 acgattatcg cacagttccc attcattact gacccagagt ctgaggttaa gaaagctaac 39960 gaacagcgta aggaacgtat gaagattcaa gcagagatgt caatgcttaa acagactaac 40020 ttaggacaag tcgctacatc agatcaaaac gtcaagaagc tagacaatcg aactgatgcc 40080 aatacgatta ccacagacga tgcagtagct gctaaagagc aggagaaatc tcgtaacaag 40140 aaaccaagag actaggagga attatagatg gctagaaaga tggggaagaa gaaacgccaa 40200 gaacttctgg aagcctttct gacagatgtc atgatagata ctcagaaaga ctttgcagat 40260 attatcggga ggtactctcc ccaacttgag gctgttgttg ataagattat catagaagct 40320 atgaaagagt ctccagacta tatgcttatc caagactcca agagcttact agaatactac 40380 acctcagtct atggtacagc cttcaaagaa gagcttacaa aagctttcac ggaggttgct 40440 gaaaaggtcg tgggacaccc ctcattagga gaggggatag cctctgtaga tataacgaac 40500 gcaattcaag agcttatcga agaagcttac gactacttct ttagcatctt acttccgata 40560 ctctatgaat tggagggcgt agctacagga acagtcgttt taggagagag tcaaggcaag 40620 ctcgctcact tagaacagct tagagacaac cttctctact tcctcagacg acatgtagag 40680 gctcaagcct cagtaattat aaatcttgct gttgtggaag cttccaaaca gtacgagata 40740 acattatgga aatggagcaa tagaccagag ttaaccgtta gtggagtttg tgagcattgc 40800 aaaagcttag ctcacggagg tatcagaaac gagggtctct ataccctaga aacattacct 40860 cttctccctg tgcatcctca ttgtgtctgc atcattgtcc ctgtaatctc gtaggttaaa 40920 tgttaaagga cacctaagcc aaggacttta caaaatacta tatctaaagc acggtagggc 40980 gttgtaccta cgagggcgga aggagaaata caatcatggc agacgaaatt atgaaagaac 41040 aaggcaatgg gacagcagaa ggcacagaag ggttatctgt tgaaactgtt ttaggagcta 41100 tcgaatccaa tccagaactg cgtaaaagcg tagaaagtca attcttaaac aaagatacag 41160 taggaagttt cttagaaacg gaagcaggca aatctatcat tagtcctcgg ttagaccagt 41220 ttgcatccaa agctattgag tcttggaaga gtaagcactt ggaagggatc gttcaagaac 41280 ggttacaaga attaaaccct ccagaaacac aagagcagat tcaacttcgg cagatgcagt 41340 cacagctcaa agaaatccaa gcagagaaag accgcttagc aatgcaaagt gtggcttcag 41400 ccgcattagc agctacagga cttccggcaa gctttgcaga ctacgtgatt ggagattctc 41460 cagaagctac gaaacacaac gtcaactctt tagacgtaga aatcaataac ctcttgtcac 41520 aacgtgtgga ggaaaaagta aaaggccttg cagctcagac agcacctagc aaccaagata 41580 ttgtaggggt tggagggcag cgagaagcta aatcattatt cgacttatct cctcaagaag 41640 ctatgcagct taaagcaagc aacccagcta agtacgaagc tttgcgacgt aactcttaat 41700 tagataagtc catacgaaaa ggagaataca catggtagca gaagtaacta aaattgcaga 41760 tttaatcaac cccgaggtca ttggagactt cctagagaag aaaatgatcg acaaccttat 41820 cttagcacct ttggcagata ttgacaatac tttagtcaat cagccaggcg atactttgac 41880 agtacctcaa tggaacttca tcggagaagc tgacgacgta gcggaaggtg tagcgttcga 41940 cccagttaaa ttgactgcaa catcttctac agcaactgtt aaaaaagttg ttaaaggtgt 42000 tacattgacg gacgaggctg ttctatcagc ttatacacaa cctgtcaatg aaactgtacg 42060 tcagttagct ttagcaatcg caagcaaaat cgacaacgac tttgtggata agattaaagc 42120 tttgactcca tcgactgatg ttaagattga cccagctggt tacggatggg tattggatgc 42180 tcaagtagct tttggagaag agttcgacga tgaaacattc ttgttcatct ctcctaagag 42240 tcgtgctaac atcttgaaat ctggagactt cgttcacatt gaccaaggac gtaagatcat 42300 cacaggagaa ttgggagagt tgttcggtat gcgtatcgta atctctaaca agcttgctaa 42360 cgacgaagca ttcgttatca aacgtggtgc attgaaactt attatgaaac gtggctacaa 42420 cgtagaaaca atccgtgaag gtttcaaacg tcaaacgact atctccgctg accaacacta 42480 cgtaacatac gttcaagata ctacgaaagt agtttacatc aaaggaactg ttacacccta 42540 atgcgcccca aaatcttagc tcaagcgacg tcactgcccc tagtgtgacg ttgtcttggg 42600 aatagggaag ggggaaacta accgtggcaa ttacttacaa catttacaaa ggttcagaga 42660 agattgcttc tgacgttgcg gaaaagactt acacagtaga cggcttagac ccagctaccg 42720 aatatacttt tggagtatct agagtagata acggtacaga gtctgcgaag gctactttta 42780 aagtcactac agcagatcag aaagtaactg gtatcacacc ttctcagcaa actatgtcaa 42840 ttaaagtagg agatgctgac cgagcagttt cattcgctgt tgcaccagct aatgctacga 42900 ataaagagtt gactattgaa tcaactaacc cagcagctgc aacatatgtt gggggaaaag 42960 ttcatccagt agctgagggt acaactgaca ttaccgcaac tgctaaagac ggttctggag 43020 taactgctaa aattgctgta acagtatctc cagcagcgga gtaagactaa caaggggtta 43080 gggaaagaat ccctagcctc ttttttatag gaggtcatta tggaagagca aaaagcttta 43140 ttagatgctt tcaacgccta tcaacaagcc gaccttcctc cagatgtaga agctattgat 43200 atatccgaaa tcaagcttat gctaggctac ttcaactcgt ctattcgaga caacttgctg 43260 aaagtcctta agaaacgtgc cagacagcat atctgccaag ttatcaacgt cgaggtaacc 43320 aaattcccaa tggagcttga ttacatagcc gatgaactaa ctgccgcaag gttgtccagt 43380 ctgaactctg aaggacttaa aacagagtct actgacatca ctcgttacga ctacaaagac 43440 gacatctatt taaactggat gtcaactctc cacgcatggg ctgataacaa cggcacatac 43500 aagggtagaa agtttaggat gatgtgatat gaagattaat gaaatcattg accttatcca 43560 gtataacgac tttactgata ccgacgacga cttcggaacg attatcccaa cgcctaccat 43620 agttgctaga gggattcctg ccgctgtcgg aagcatggcc acagaccaga agctacttat 43680 gaaccaagat gtccaatggc ttccaaggta tcgggtacag cataagatat acgagttgaa 43740 agacttagta attgatgcgg taagattcca ctccactggc aaggtgtata acatctatga 43800 aaataatacc actggagtta accaaacagt ctcttaccta gttgagtacc gagactatag 43860 acgtactaag gaggatggta ctatatggga agggtacgaa tagacatcat caagaagatt 43920 aacttcgaca aacttatcga cgactggttg gatgagactg agagagctat ggacacaaat 43980 acccaccaga tgagacaagc tgttaagtat aacatccacg ctcatgacaa cattgatacg 44040 tctactttga ttagcaattt agaggctgag acaaaagtct ccagaggagg gcgtatctca 44100 tatggaatag ttaaatcaaa cgtctctgga aaccctaaag gacacagagg ctatgctcca 44160 atcgtcgaac gtaactaccc aaactttata ccagctttgg aagagtatac ggacaggatg 44220 ttggataagc ttatgaaaat taacatctag gaggattctt atgagtagac cattattccg 44280 tgcaagaagt tcctccgtaa gtcttcaacg agctatcgta aaagctctca gagcagaagg 44340 tataaacgtc tgggatggaa ctaaaacaat gcccgaacta ccttacgtaa agattggcga 44400 agagttgaca tctggtaaag tcacctcaaa agatacttac ggaaagatgc acaacttaac 44460 gctccactta tggagtgact acccaagctc tatagagact aaagctctgg gagacttttt 44520 ggtagatagg cttgttaact ctccattaga actggaagat ggcttttgcg tagtcaatgc 44580 aaatcttgac cacgtgcgct ataccgaagc ttctaatgga acatttaaaa acaatcgagg 44640 atacttgttc ttagactttg aagtcgcaga ctctttagta aatccacgat aagaaaagga 44700 gaatacacat ggcagaagta tgtaaatcac gcttcgtacg aggcacagcc gttctgattg 44760 aagttcaaga tgaagctggc gaatggacta aagtagcagc ccaacgaggc ggtacattaa 44820 accgctccgc agatactttg gacaccacta acaaagaagg tttcggatgg gctgacaacg 44880 agcaaggcca gaagtcttgg tcaatcgatt gtgacggatt gttcgtagag gacaatgcag 44940 gtttccaagc gttgaacgca gcttgggtaa atggagactg tgtacgtgta cgagttcatt 45000 tcccatctgg cttgacatat gttggacaag ctattctgac agacttcccg atcgacttac 45060 cttatgacga tgctgtaact tacagcttga cattcaatgg taaaggtgct ttggaagagc 45120 agcaagtagc tccaacagtc tttccaacag gcttgacagt aaatggggta ccacccgaag 45180 gtattacagt tggaggaaca gctacactga ctccggtatt cactccggaa aatacttccg 45240 ataagtcggt tacgtacact tcattagtac catctatcgc aactgtagat cagagtggta 45300 aagtaactgg tgtaaaagct ggtacagcat ctatcaacgt tcgttcgaca gtcaacacag 45360 caatctctac aacagtagat gttgtggtaa aggaagcata gcagtaacgc caccaagcaa 45420 cctaatgtca agcgacgtta ctgcgacatc tgttaaatta gcttggcaat aacaatcaag 45480 gggttgggga ataaatccct agcccctttt attatggagg actagacatg ctaataaaat 45540 ttcaaggaaa gaatatagac ttgcgaatga cttataaatc aatccacttt cttgagttag 45600 ccttcgggaa agcttacata gacttcgtag cagagcaaac gccctttaac cagtctctct 45660 acttattctg ggcgatgcta caaaacattc ccgaatatga gggcaaagat gtactggaag 45720 tatctgatct tctacaaaag tctctagatg agtatgaatt tactttaaca gaatacttcg 45780 aaaaagtcaa tcagagttat caatctagta ttataattaa acaactcttt gagaaagagc 45840 ctaacccaga tgaagaaaag tctcccagaa acgtcggagg acgtcgattc tccgctttta 45900 gacgtaagat acttcatgat attatgttca gacttagaaa tttcagtcaa cgatttctgg 45960 acaagcactc ctaatgagtt taatggattg atgagaggag cttaccaacg tcatgcaaga 46020 gaggctggac tgttctttac cttgtttaaa cagcctgcta aaggtaagcc aataagctac 46080 gacgaatatg ttggttttaa actttacaga gacctagact atattccaga atccgagata 46140 actacggaag acttactgag agatatggac gaggaagacc gtagagcttt tgccaaacaa 46200 gaattagaca atgtatttaa tatgtttgat taggaggaac tataatggca gataaggaaa 46260 tgcgaataaa ggtttccgta gataataacc aatacgtcaa agccatgcag tctatgggaa 46320 aggttcaaga tggggttact agcaagcttt ctcagtctgc taaagtctta tctggaacta 46380 ctggtactgt tgagaagtct cagaaaggta ttctagggat gggtaaagct tgggtatcgg 46440 ctaacacagg cttaggtacc tttactgctg gactaactcc aatgactgct gctatctcgc 46500 ttgggtcaca ggctgttaag atagctggta agtatgctat tgatgcagtt aaaagctatg 46560 ctacctttga aggaactttg aaacaggttc agatagttgc tggaggtact caagcagata 46620 tggacatgct tggggacaag gctatcgaaa ttgggggtaa gacttccaaa ggtgctcaag 46680 aagttgtaga ggccatggta gactttgcca agttaggttt tacagctact gagacagccg 46740 atgcaatgga gggtatcgta tacgcagcag aagcttctgg gtcagctgtt gatacaactg 46800 ctcaaatcgt tgccgcagct ttgaatacat ggaacctagc agctggcgac tcggaacaca 46860 ttgccgatgt tttggcagag actgctaaca agaccgcagc tgatatgaca gacttaggat 46920 ataccttcca atatgccgga gcttctgctc agttgggggg agcttcaatg gaacagcttg 46980 ctgcctatac tggtatcatg gctgaccaag gtatccgagg ttccaaagct ggtacagctc 47040 tccggacagc ctttacaaac ttaacttccc caactgataa ggcagcggct gctttagatg 47100 aattaggaat caagttagaa gatgccgaag gtaaggcacg tcctatccca gacgttatcg 47160 cagacttaca gaacgcagct cagaacatgt ccaaagctga aatcctagat ctatcaacaa 47220 tcttatttgg taagactggt gcagctggta tgtcaatggt cttgcaaaag actaatcaag 47280 agacagacga cctagttcaa tcactggtta actccacagg tacagcagct aaacaagctg 47340 gggagatgcg taagactatg gaaggacagc tcgaccagtt agaagatagt tgggatgccc 47400 ttaagctaaa gattggtaaa ggcattactg gtactattgg acttaaaggt gtagaacttg 47460 ctaacaaggg tttagactta gttaatgatg ccattgatgg agttactaaa caatttgaca 47520 gaatcaaaga ctatgagaaa tggtttggaa cagttaaaat gccgtgggat gagtgggcag 47580 aagctttgcg cccaacttcg acagaggcta gtagatttac agaagctttg gtaaatatga 47640 aagacaacct catggaagtc caaactcaag accctatttc agccatgttt ggaagcaagg 47700 cgcaggagca gattgaatta gttaaccaag tgtttaaaga cctagacgct caagcagctt 47760 ctttcagctt tatctccgca gataagctag atgagcttac ggtagctact ggtacagttg 47820 tatcaaccct acaatctact agtgcacagg ttgctgtaga gactgctaaa tggcaggctg 47880 accctaacta caatccatcg aaggctatag cagcagccgt tcaaactgga ttacctgact 47940 tacagacagc tttgcaaact cagcttacaa cgattcaaga aagcaatacc aacaagatga 48000 acgccttaac cactttcatc aacaatagtg atatccttga caaggatgct aaagccaagg 48060 cactggctgc ccaagccaca cacaatgcta accaagaaca atccatagct gctaacaata 48120 ctaagattct ggagctgtat tctaaccttg ggagcatgtc tgtctcagaa cgtgaatcag 48180 ccttggcaca gattgacagc ttgacccgcc aaaatgctca acaagtagtt gacctaactc 48240 aagctcagaa agattctgtc atcttagcct tacaagctca ggcagactca tcaggaagaa 48300 tcacacaaga gcagaaggat aaggctattc aagatgccaa tgctcagaga gactctactg 48360 tacaagcagc tcaacaacag tatgtccaat ctgttgctgc catcaagagc atgtccgatg 48420 aagctgtagc agctactggg aaaactcgtg ataagttgat tgaagatgct cgtacacaga 48480 tgattgagac ggttgataaa gctcagacga tgcgtgatga tacggttgag gctatcgaag 48540 gtatcgagac taaagctaac tcggtagatg gtaaagagat tactgtaaag gctaaaaagt 48600 ctgggttcga cactgttatg acagctatcc aaaatctaat tagtataatt cctgctggag 48660 gggttatcaa cctagctgta aacgccacta ggactattgt tgaaaaggtt tctaagtggg 48720 gtaaagctcg gggaggtcta gtctctggag caggcactcg caaagcttct ggagggcttg 48780 tcagtggagc tggaggctat ggaataggtt ctggttcagc tacctataac cctaacatga 48840 cagcctttgg aacaggcaac caattgggac aaagaggcat ttcacagggg gttacacaca 48900 atgaaagagg tcgagaagcc atcatcccaa tccagaatgg gacttacatg agaccattcg 48960 caagagctat tgcagacgag ctgaaagctt ctggagcagc aggtggggga gatattccag 49020 agatcatcgt acctgtttac ctagacacta cggaaatcgt cagagcaacc tctaaaaaga 49080 tgactgagca acagcagttc gatgccaagc ttacgaatcg accgaaagga aagatgaaac 49140 gatgaactca acatacgttc ctgtatatac tcctcatacg acttatccct tagccccttc 49200 gttgggctgg gggattggcg atgctctagg atggattccc tataacgtag actccatgac 49260 agagattacc ccagcttctg gaacaactta tgtacagtct cagcagattc ccgagaatgg 49320 tattcagatc actcttggat tcgatgtgat gggagctatt gcaagagagt ttccggagtt 49380 cttccaagac tgttacattg aggcagacaa gattgccaaa gtccgtgaaa ggactcgtga 49440 gtatctcttc tcagtaactg ccaatcataa tgtggaagta tacttagaaa gtgaagatac 49500 acagcttgct agaaagtcta ctggaagtca aggaactttc acttggacaa tatcttctga 49560 gaaacctttg gacgactata cgtttgacaa tggatgggtt tatctgtcag tagtcgtgcc 49620 agcagctact tcactagctg acctaaacct gtcggcaaca gtcacaccta agtttctatt 49680 tgacccagtc tatgacacga agcctcgaac attccgttat aatggattga aacaacctta 49740 ctacctattt gtaagagaca tcaaccgctc tgtgctacca gctgttaaca accttctgac 49800 agcctatgac agaggcaaac gcaacttcaa ctatggaaag acttatggag accgtgttat 49860 ctctatgaac tgctttatca aagccaataa ggaagaggat attccatatc taattgaaga 49920 cttggctaac ttcttggaca ttggagaaac aactattcga tttgccgact cgaaagaccg 49980 ttcttggaaa gtcgtatttg aaggagcctc tgagatcaat caaagcctta atgtaggaga 50040 cttcacattg aacttccggt gtatcgaagt aacctcctat ggagacgaag taactgggca 50100 agtaactatg gatactgacg aaggaacctt cttccaaatc ttcaatgagg ggacagcaga 50160 gactcatcca gttatgaaaa taacctttga agaagattct ccaatggtta acattgtagg 50220 tatgggagag tcagagaacg taactcttgg ttatgactcg tcggaaggaa ctggaactgg 50280 tacaaacttc gacccaatgc cttggcaatt ctcagagtac tatgacaaca tgaatgcatt 50340 gaaacagatg gataacaata caactcctag cttcttatta taccaagatt ttatcagaaa 50400 tacaaccctt gaatctactt atggaacatt gatgcttaag aataacaagt tccctaaagt 50460 agaccgtaaa acagttgggt acaaatggta tggtggaggt attacgaggg ttaaccctaa 50520 agccttgaat gactttgcct tagaggttgc tttctcaact aagggaaatc cccaatactg 50580 gactgaccac catatgtata taatcttata tgacgaccag atgatacctt ttgcaaacgt 50640 agcttttggt tatgtagcta agcagaaacg catacgattc catattgcaa ctatgggctc 50700 atctactcaa gatgaagttc gtatcagccc cggatgggga ggtaaagagt ggtacaactt 50760 tgcaggtaag attatcattg agcgtaagga caaccgctgg aggcttcaag caggccagtt 50820 caagtctcag aaacgttctc caatgattgg ctctgactta caatacggct catcaatgat 50880 gaagaacgta cgctcaacag gcttccgttc gcttcctcaa gagacttgga ataggaagtt 50940 tgcagcttat ggaatcttgt atgcaaacat tgacaacaga cctcagatta accgatgggc 51000 agtccatcac actaagtgct gggaaatctt gcaaaagcct gccaacagcc ctcagataac 51060 tcgctcattc aagaaagacg acgagcttat cgtggacttt accaaaggcc aagtatggct 51120 taatggaaca atcgccccat cttatgtaca gccttccaca gactggttct cgttgaagcc 51180 aggcaagaat actttgggaa tatctggagt aaagggtaag gtagagtatg agtacaccaa 51240 tcgctacaaa taaactttag gaggaaactc aatgattaca gtcttaagtc cacagggagt 51300 atatcgtgga aactacgtaa ataatattcc aaacgctact ccttattttg atgacaaatt 51360 taccgacaac ttagaaacaa tgcagactac tcttgagttt gcagtacccc tccaaagcga 51420 agatagtgaa tggctggaag gattcggcac agtcttgtac ccagataaag acaacgttct 51480 tagagagctt actatcatca acgtgtggga ggactggtca caagagcagc ctctcaaacg 51540 agtggtgtgt gaagactcct ctgtggatgc tttgttaaag tctcacgtgg tacctttcac 51600 agcaggtaac ttacgagatg ctattgcagg ggctttacga acaactcctt gggagtatat 51660 tatcggatct gatacaatca acatcggcta cgagttagtt gacgtaaaag agtacacgga 51720 tgtccgaagc actttggaaa aaatacgaga gctgtacgac atagagtatc gctttagtgt 51780 taagtttgat ggacaacgta tcacaagagt gctccatgtc tataaacgct ttggaagtaa 51840 cactggtaaa tactttgtat atgaccgtga tctaatcaac attgagcgta cagtagactt 51900 cgacaatatc catacagcca tccttcctta ctggatggaa caagacgttg ttagaacgct 51960 tgcaggatac tctcctatta acaaaattaa tggattccgg aaagacaatc caatggatat 52020 tatcattcat gaatcagctc acaacgacta tgaccaagga gactatgcaa aagtccttat 52080 catgaagtcg tcttcaacag accccgaact aacttatctt gaagcttgta ataagctgtt 52140 ggactacatt gctccaacgt atacgtacac agttaacgta ctactccttg agaatgcttt 52200 gggctttgaa gggactgaac aaatccatct aggagatact gtatggctta aggaaaaagt 52260 tggggatatg gagttaggtt tggaagctcg ggtagtcgag ttggtaactt ctcataacaa 52320 tccagaagac gaccaagtaa ccttcactaa cttcaaagag atttccacag ctgactcgga 52380 agatgtctta gctcttcggg atatgattaa tcagattcaa aatcagcaag accaaatcag 52440 tcaagtggtt gtccaagtaa ctgaggacat cacagtattg caacaaggcc aagaaggaat 52500 cattggacag cttggagacg tgccttctgt aagcgttggg gatacgccta ctccaaatcc 52560 taaagaagga gatatctggt tccttgatgc agttgaccca gatactggta agacgtattc 52620 aacaattaga atatggaatg aaactaccgg agaatggcaa gaccgatact ctgcaaagga 52680 tgccgaagaa gcgcaagctg ctgctaacga agctgctcaa gcaggtaaag atgctcaagc 52740 tgctgccgat gctgctaaag aagctgccca agatgccgca gcagctggtc aagcagctct 52800 tgacaaagct aatcaagcag ttactgatgc agccaatgca aaagctcaag cagatgctat 52860 tcaagtagat gttgaaggac tccagacgga tgttggcaag gctcagacag atgcctctaa 52920 agctctaaca gactcttcta cagcgatcac aaaggttggt caagttgaca gcaaagtaac 52980 gactgtcacg aatgatgtta acggtatgaa aactaccatc tcagacattg agacagttca 53040 aggagagact actcagaagc ttacggaagt tgaaacgaat gttgatggac ttaccgtaac 53100 tgtagggcag gttaaaacaa cttccgactc agctctttca aaagctacta ctgttgaaac 53160 tactgtaaat ggtttgaaag taactgttgg agaagtcaag acaactgctg acggagctct 53220 ggcaaaggct actcaagtag aagctacggc agatggtctg aaagctacta ttacagctgt 53280 tcaagaaggc atcttaaata gtgactactc taatattatt cctaattcta aaggggattc 53340 aaccaaaggt tatgtagtat ggggtggagg taatttttct acagacggta cacagatagc 53400 tgtaacaaaa ggaactgcta caactagtta cggaatccaa acagattatc tgatagctga 53460 tgttgagaaa gatgcaacgt acactttaca actggaagtt gggagctttt acaatacttc 53520 tgtattagac tactgtttct taatgtatta tgacggacaa ggaaatcaaa agctcccaga 53580 tattcctgtc tttgctggat cagctagttt ctacacacgt tctattacat ttaagcctgt 53640 aagaagcggt aaagtaaaag ttcttttagt agttaacttg tctaataacc ctacctccac 53700 tggattccgt ataaagaatc taatgatgtt taaaggtgag tcatctttgc gagcatggca 53760 accagcttac tcagacttgg caacagttgc taaagtaact caagtagaag ctacggtgga 53820 gggtcttaag acaactgtat cagaagttca aactactgcc aacaatgctt ttactaaagc 53880 tacacaagtt gaacagactg ccaacggtct taagacaact gttgcagaga ttcaaacagg 53940 cattgcagac ttgacgaata agttccctga cccagacttc aagaaacaga atccaaagcc 54000 taccgtagag agtacagcca ccttctcata tgcagcagat ggattgcttg taacaaataa 54060 tggaacaggt tctgctagaa tctactgggg aagccctcct ctagctttgg aggtcggaaa 54120 gtcctataac gttaaactgt ttgttaatgt aggctctgct tctataaata aaccttacga 54180 gataggattc tccgagggag aaaatcttaa attctctctt ccagattcta ataatagatg 54240 ggtgcaagga actattagat caactcagtg gacaggattc agtctatttg tgccaccttc 54300 atcaactatt aaagttcatg aaatgtacat ttacgaggct aatacaaacg ttacttcttc 54360 ccagattacc caattagctg accaaatcaa tttgaaagtt gataagaatg gagtcattgc 54420 acagatcaat gtttcttcgg aaggagttct gatagacggt aaatacgttt ggatcactgg 54480 attgactaag attgacaacg ctattatcaa gactgcccac atagctgacc tagctgtgtc 54540 aaacgctaag atagctaacc tagcagtcaa cggtgccaag attgctgatg catctattac 54600 aacagctaag ataggagacc tccaagtatc cactgccaag attgctaacc tagctgtcac 54660 agatgctaag ataggctctc tatcagccag caagattaca actggtacac tggatgctgg 54720 aaagattagt gtaatcaact tgagtgcctc tagcataact tctggaacac tctctggatt 54780 gacaattcaa tctccttatg atcgacctat aacagatggt tccacaactt ggcaacgagg 54840 aactcttact ctaagtaacg gtttatatac caatgagtgg gaaacctacc ttaagtctac 54900 aggagttaaa aacatttcag gtaagctaat tattgaccac caagcccttt cttcttatca 54960 attggatagt tctggacaat tagaatataa catgcagttg tctccttacg cactaacact 55020 tcaaaccaaa gatggcaaag gcggttcgtt ttcctacaac gacctttaca gtatgccaag 55080 gactggtcta cagcctgcct ctggatttga acagtatagc acgtcttcta gttctggtca 55140 atggcctact gctactcgtc tgggaaggct agtacagctt gctggagcat tcaagaatat 55200 caacccaata gctggtagtg cagatgtcat acagattggt attctaccta tctgggcaag 55260 acctaaccaa actaccaacg ttatagcaca gggctctggc atgaataggt acttacttgg 55320 gctagagcct ggaggtgcta tcaacatgag ccggtatggt tctggttcaa gatatgaaca 55380 agttggtaaa gggtcttggt taaatatagc tacgacatac gcaggtgcag atgtttagga 55440 ggaataataa tgacgaaaaa tcaagaactg tttatcaaac tttgggaaga gtctgggcaa 55500 gagtttacgg acgagttgct caagcttttc gatgtaatct taatggagga tttccatgac 55560 aacccagagc ttatgagtaa gtttatggaa agtattcaaa aagttcccga accaccttta 55620 gagcagcagg ttgctatgct tcaagaaact gttctacagc tctcagaatt aattgcagga 55680 ggaatgtaaa atggataaat actctccact agcacgtctc tacgccctag ctattgtaaa 55740 aggcttgggc ggacggacta tcaacagtgt tccatctagc ttacgtgaag acgttcaagc 55800 aatcttggac aatcatatgg acgaactaaa agcaatgtta taggaggaag ccttatgcaa 55860 agaataaatt tagatacttc tagaaaggct accaaccaag acgtaaaggt ttatatacga 55920 actggggaaa aggagtttac aactatcgga gtcagtctta caacgtatgg tattccgaac 55980 gacttgactg gcttcacggt aaactttgaa ggagctaacg ctgagggaag attcagtggt 56040 ggaggtgcaa gggttgtaaa cgccactaac ggtcagattg aatacacctt cacgcctacc 56100 gatgcagctg tcgaaggctg gttcgaaaca gcttacttcg tcattaagaa gggagatgaa 56160 atcgagggca ccacagaggc tttccgagtc catgtaagcc gtcgggtaga cattgatgat 56220 gcacaggcag cagctggggt aaatactctg caagagacta ttaacgcctt ggaagctact 56280 ttcaatgagt ggaaagctgc tcgggaagct gattatacag gactacagac acaggctgat 56340 gcactagcca ctcaaataac ttctgcaaag gctgacttgg atgctaaggt agcagcagct 56400 caaacagccg tcggaacagc taaggcagag gctttagcag cagttgacga tgctgttgca 56460 aaactgaatg cagccattga agattttaat gcagctgact tctatactaa ggcagaagcc 56520 gatgcactgc tgttgcaaaa ggttgatcga tcgtcttacg atggactgta cacaacttct 56580 aaagtagcta tcactccaat gagtggattt gtggaataca ataccaacag cgcttcggca 56640 aactttccac aggctatcag aaggtttggg gtggtaacta ctaaaggagc tttcaaaaac 56700 aattcagagg tagtattgtc gggtaatgat gccatattta ccatgggtca actcccagta 56760 gggtatcgcc cggcagagga tttgaacttt atcgcccaag gttcatggat gaacaagtat 56820 cttgttactg ttactaaagg tggtctgata actggcgcaa ggtatggtac taactctaca 56880 gtaaacattc cagcaggctc ttggctaaat attggaatga ccttcgtagc attagaacag 56940 gacacctaag tcattttgtg ggtctatccc acagaggagg aattaacata tgaaatacat 57000 taataagagc gtttgtcgag gcgtagcagg acgacgtgcc agaggatgga agcctttagg 57060 tatcgttatc cata 57074 <210> 2 <211> 42957 <212> DNA <213> NCIMB 43666 Genome <400> 2 tgatacaatg aaatacaacc aatttaaggg gtttcctctc aaagcgcgta ctaaaattcc 60 cgcgataaaa gagtggcaag ctcaagagag ttacaaaaca ttaggtaaaa taagaaacat 120 gaataaaggg gtcttatgtg gggaacaaaa caaattatta gtagtagact gtgacgtaaa 180 aggtaaagca aacggaatac actcttttac taccttaatg aaagacttag gacatgaaac 240 catacctaac accctaatgg tctatacacc gtcaggaggc atacactatt attttacgtt 300 accagatgac gcactagacc tacgcaaaca acctagagag gacttaggta tagattttca 360 gatgaatggg tcctttgtgg tagcagtagg gtcagagtta gaaaacggga catatagcgt 420 ggtttccaat aaaccaatcg cacaagcacc cagagaatta attaactggc taattgagaa 480 cgcaaagcaa cataattacc caacgaacgc aacgccaaac caattaaaca gaagtctaga 540 cgcatggttt aagatgttag cgtatgagag tggtaaaatg ggtaacgaac catggcgcct 600 taacggatgg gtatataaat ggaaaaagtt gacaaactta gatatttcaa ctataataga 660 aagtgttaaa atcgttttta aatacctata tgggtttgag cctcctgtag aactacagac 720 gaacaaagca aggggtaaag aacactcaaa cgcactttca cggttcttag aatcacttgt 780 atatacacgt atagacgagg gaggacgtaa caatgcactc gctcagacag caggaatgtt 840 agcactggga acgaacaact tagacctgta taaatgggcg tgtaaattgt acatgacaac 900 ctgtttcagt gaacctcttg acgagagtga gtttgaatta acagtaatga gtatttggaa 960 acgtgaaaaa ggtagatgat tatatgacac ctgttattaa tgaaagcaat gagacccgta 1020 ccattaccat ctgcatggtc aacggacgct cttacacata taagggttcc ccagagtttg 1080 ttattgaacg tatgcaaaca ggagaggttt ttcagattat gctactaagc tctgtgcccg 1140 tgaatgtagt aatacaaccg tactacattg ttagtgttga atattaagga ggaaaacaat 1200 ggttaaagtt aatgaactaa aagtcggaga tgttttaatt tacacaggtg agtttaatag 1260 tgtaaattgg aggtttggca aagagtaccc cgtgttcaac ggagacggtc aactatatgt 1320 tttgacagat atgcataata tgtattttat ttttgaccat gaggaatata ttgagtcaaa 1380 atttgaactg aaagaaaagg aggctgtaaa ggaaacggga attgtacaca aagccaaaat 1440 gtacgtgcgt ttgaaaattt tcccaatgga tggctctaac gcgcgcgtaa acgaaccact 1500 cctacatttc tttctcagtt tttatgatta tgcagacacc tcaacatgga gaggcaaaga 1560 agttttcata caagggtgga taacaagcga taacagacgt aaactaatag aggaaatttc 1620 tacctttttt ggtctaggtg ttgaggagtg gtaacgtgtt agaaagtacc tattcacaaa 1680 aagttaaacg atttgttgag tcacacggtg ggatgttcct tgtaaacaca gcaagtgttt 1740 atgacaaagc aggacgctct gacgttgaaa taatttacaa aggacatgtg atttttgcag 1800 agttgaaaac agacgggtac caaccaacaa gcctacaaat acgtttttta caacgcgtga 1860 gagaacaagg cgtcataggt ctcatactaa aggatgaact acaggagtta gaaactattt 1920 ttcacttgat agacacggga cacattagca cgtataaatt gccaaaatta ccagagatta 1980 aaacatatga cttatttgag gaggatgaat agaatggaac taacattaca tgattttgag 2040 tataacgagg atatgattga cgtatatgat ttagatgata cgttagtgtt ttatactagt 2100 gagaaaatag ggagtagtac agtcaataca cagattagat tagacaagaa ggcacaaatg 2160 gaattataca aggtattgga caaacattta tttggtgact atgatggtaa agttatggag 2220 tctctagaac cttatgagaa gacgggtgat aggaacgtta tggagcctct agaaccctat 2280 gagaagacag atgatagcaa agtaatgatt gacgctgagg agtttagaga caagattaaa 2340 catgatacaa cgatacgtga ggcagtggca taccttgacg gatatgttga gggtaagaaa 2400 aatgactaaa attctactaa tgattactaa ctcacgcggt gatttgtttc tagagaccat 2460 tatggtcaga aactcagaca atataggcga aattgttgat aactatatga aagagcgcta 2520 ccagagtggc gtaacatatg tttgggaaaa agtaatagat aattagaaaa ttctaataaa 2580 actctaattg tattttaagt acagttagag ttttttatat tatacttagt tcataaagtt 2640 aagggaggta acagcatgat aaacaaacgc aataataaag ttattgatgt tattttcaca 2700 gatgaggtgt tcggagggtt gtgaggtaaa ttagacgttg agaatgacat aattattata 2760 aaacttgaga gcttagaaaa ggcgctccct actcgctatt ggaatacgtc tataggcagt 2820 gaccaactaa aggagcttta taacatggct gtaaatggtt tcatatgtgc aaacgctaat 2880 gagtttgatt gggtacaaat accagacgac tatttaggag gtaataagca atgagtaata 2940 tgtttgaggt aggtcacaga gtagtatgtg tagacacttt atgtgtagaa gatatattgg 3000 aaaaaggtaa acgatatacc attgttggag taggcagcct tttcgtgcag gttgatggta 3060 ttgatgaatg gttctactat gaccgttttg aacgtgacta tgttaatgag ggaattgaat 3120 atagtttgaa agataaacat ggtgctacct tgagtgtcgc taggttatat aaagataaaa 3180 cagtgattaa aattactgat tttacgaatg atgtagtaag cgtacactta acagacgcac 3240 aacttagaga cttgagaaaa attttgaaag aagtttaaaa atagtgttga cagatgacta 3300 atcgtctgat aatataataa atgtaagata actaaggagg aaaacagatg gaaaacttaa 3360 cagatttaga cttgctttgt ttgtacgcag ttatgggagg agcaacgggt aagcaagtta 3420 ttgagtatgt aaaacgagaa caagaggata aggagtatag cgaaaaggct atatgtgttc 3480 tacaagaatt acagcgttct gctgaaagct acggatggta taacttgtca gatgtggcat 3540 atatgaaaat tagattagaa ctagttcaac gtggtttgtt ggatggggat gtcaaagaaa 3600 ttgaggggtt cattaaagcg tgggaggact cagaaaattg attgcatacc taacgccatt 3660 agttataggg ttgtcactaa tgttttctaa atggttgttt caaccaaata agggaggaaa 3720 atagacatga atttagatac tacaaaatta ggtgatttag tggttgaaaa ggcgcgtgag 3780 ttaaatgaga aaacgggtat tgagtctgct gagttacttg tcttcagtgc tttagtaact 3840 gtgactaatg ttattgatac tgtattaatt gacggtgact cacctactga attagcacta 3900 tacgcgctta acgtagtaca gcaaaatgtt gataacgagg acttattaaa tgaagttgag 3960 aatataattg ataaactaga ggaggaatta gtttgaaaac atatgagtta gtaaacaacg 4020 agacgacacc tttaccaatt ggggcagtct tgtacgaact acctgaaaac gaattgacac 4080 ctacagagaa agtattaatt gagaaagaga aacacagaga ccctatacca tgtagaacga 4140 ttgatggtat acgtcagctc attccgtacg aacatttaca agaaatttaa aaataatgct 4200 tgacaactgg ttggggtttt gataaactaa taaatgtatt aaaacattag gaggaaaaca 4260 gatgaataaa gaagaaacac acaaagcgtt tgagaacgtc ttacaggaac taaagtttga 4320 ttttgataag ttgaaatacg gtaaaaaagt agatgaggaa aaacttgctt tcaacattat 4380 tatggcaagc gctttaggtg ctaaactcgt agatgagtat gggtttgata gagacacgat 4440 ttcagaccgt attgacgatg tattaggata aagggaggaa aacaaaatga gtaaagtatt 4500 tgaggataat tttactaaac ccctaccagt ggggacgaag gtgcgcttga ttaaacctga 4560 accaactgaa ttttttatga atgagggtta cgagcgtgac agggaatacg ttggagaggt 4620 gttcagagta gctcatagcg ctgaagaaat tgacggacaa acgcaccaac ttgaactaag 4680 tattgatggt cacctatggt gggtatatga taaccaaatt gaggtattag actatgagga 4740 ggaaaaataa tatgacaaaa ttagcagagg tattagaatt acatgacgcg gagttagaca 4800 atgttttaga tgaattgcgt gcccgcatta tggacgagcc taaagaatta gacattatga 4860 tacacgctcg tctaatgttt gcttacaatg tactgcacgc acacgctgtg gggtttgaca 4920 ttctagagtc aggaattgta aagagtgcta ttacacagat gattgacgtc tgcgatgcgg 4980 tagatatggg taacctttta gggggtaatg aaccagacca aataattgga aaaattggtg 5040 acctcatgaa taacctagct actgcataca atgacacaat tgacgaactt aactcgtcaa 5100 aataataaaa agcactacac gttgggagga atcagcgtgt agtgcttttt agggagaaaa 5160 acaatgtata ataagtatac acatattata ccatattatt ttataaaaag ggatgtaaaa 5220 agttgtttac aagtgctcca ttctgtggta ttattagaat ataattagaa aaggaagtgt 5280 ttataatggg tacaattatt ctaggtgtta ttttggcaat ttcattgatg ttaaatgtgc 5340 gttatagtgt agagcgcaaa tacttagtcg ccatcatgga ggcacaaagt aagtcaatta 5400 ctgagcttac gactgtcaaa ggtggtacaa agtatgagaa acgttaatac gaaacatgaa 5460 cggtttgaac ccatggacga gccttttgat atgtacagcg tttctaacat gggttacatt 5520 attaatgtgg atgatgacat gattgttcca atgcagaaag atgactcaaa cggtcgctta 5580 tatgtacgtc taacagcgcg taactcacaa ggtaaccagt gtgtaagggt tatgtatgtt 5640 gctaagttgg tggcagatat gtttgttccc aatgtgggta atgataaatt tgtgggcttt 5700 aaagatgggg acacattgaa taattgttat gacaatttat ttcatgcctc taatatgttt 5760 gacgccagtg agacaatgaa tagaccactg cgtaaagaat tagaactaat gcgccacaca 5820 ctgctctgta aaattggtca tgctctagat aatgaacagg aactagaggc gcaacgatta 5880 ggtaaactat tatggaacct agagaacgac aattcagaag aacaaacaga gtatgattgg 5940 gtgtgattag atgattgaat ataagattat aagcagtggg tcagtaggta acgcggttaa 6000 attaacattt cagaatggta taaaaatgat gattgatata ggactttcat ttaaagtatt 6060 aaaaaaagat ttacaggact gtcacttact ttttataagt cacattcatg gagaccacct 6120 gaatgttggt tgttataacc aaatacggaa aaacttccct tggataaagg tgatagcgtg 6180 taaggaggtc aatgacctac ttgtttcaaa aggtaaggca cccgttaaca ttatagtgga 6240 acacggtacc actattgacg tgagtggcgt agagtgtacg tttttagacg ctcctcatga 6300 ggttcaaaac ttaggcatta tcggaacctc aaacggtcaa agttttttat acgctacaga 6360 cctaatgact actgtggcat tcagtgagta ccttgataaa acaggtaaga aaattgattt 6420 gttactccta gaggctaact atgacggtgc tgtaattggt tatagtgaat atatgaaaat 6480 tcacagcggt tatgatacgt ataataatgg ttcctataga catttgtcag ttcgccaaaa 6540 tacagagttc gccactaaat acttgtcaga gggtggtacg agtattcatt tacaccagag 6600 tggtagttat tactcatatg agaacctcaa ggcgcagaat gggctagacg aaagacatga 6660 taaggagttt atacaatact gcaaagaaag aggttatgat tatgtataag tacgtagtac 6720 gctacaaaga ctttgatggt tcatacgtgt attttactgc attttcctca aggtcaccga 6780 tttatgatga ggaaagagga cgcacaaggt ttagacagat tgtcactgat aaaccgcgtc 6840 taaaaatgga cataacaacc gctaaaatgg ttagggacct aactggtgga tatggtgagg 6900 ttgtagcagt aaatgaggac ggtgtaatta ttggataacg agttgatgat ttacgtaggt 6960 gatgtaccat ctattgagtt tgcgcaatat gataaactac ttgatgacat taccaagtta 7020 gcaaacgaaa tgaaacaagt tgaggtaaca gaggacaaca taaaggaata taaaaaactc 7080 ctcgcacagg ctcgcaaaga gtttagcaac atagacaacg aacgcaagcg ggttaaaaaa 7140 gaaattttac gaccctatga cgagctagag gataagataa aacatctcag aggaatacta 7200 aaagagggtg aggacgcttt ggatgttcaa ataaaggcgt atagagacgc tcagaggtgt 7260 tctaaatggg atgaggtaca agttaccttt gaacgattta gagagggcta tgaggctcct 7320 acgtggctta cgtttgatat gttcaaaacc atgcacccac atttagccaa tgtgaatgta 7380 actcagtcaa aaataaatga gtcccttacc tcattctttg aacgatttga cagtgactac 7440 aggcaactca aagcgtggta ccctatacgc aaccaacgaa cctctattct agctgtatat 7500 gcaaacaacg gtttagacct aatggaggca gtacagcaat atgagaaagt acgcgctgag 7560 ggaatgcgtt tacaggagca agaaatagaa aagaaagtga ctatacgcgt ggatggggaa 7620 caggatgaag ttgaggatga gtttgttatt gttaagattg ctaaaaatga tttaggtaac 7680 cttgatgttg cgtatgagct agtataacaa cgttttacac ataaatggta taataacact 7740 atatgaaata agagagggag attttaatga gtaaagaacc tgaaaaatta acagttgtag 7800 cagttgagga cgaggacaaa agtttagtga ttagtgtgtg tcctgaggac tattctaaac 7860 tgtacacatt aacattgtac aaagaggact acaatagtaa gacaaaagaa tggactaaaa 7920 aagatgaggt tacagagcga tttaacgagg acctaaacaa aattggtggt gtccctaaca 7980 caggtgacac attagaggta tatacctctg acaacggtaa agcttattta gaacctagta 8040 acttcattga ggtagaaaaa ccgagtgcga agatggctaa taaattatta aaagactgtg 8100 ttattgagcg cattcgtgac aactcaaaag gacgcattgt aacggtagct tacaaaggta 8160 agttctatga gttttcattt aacacaagcg tgtgggtacc taccattaat aagtttgttt 8220 ataatgacgc taaagcaaag aaagcacgtg aacggtttga gggtattttt gaggagtcac 8280 ctatcacatg ggaaaacgca ttagtaaaag acagtgaggg tgagttcctt gctaaaggtg 8340 tgaaaattga ctgtcttgta cgtaagaatg agcttgacca gtcaggtaac tcagcctttt 8400 tagaacctgt gaaaattgag tcaccggatg atgacctacc attttaataa taaagtgagc 8460 gtaccctatt gacaggtgcg ctctttttgt ataaaatagt ggtgtgagga ggttttatat 8520 gtataatatt tacattaaga actacaatgc gggaaacggt gttatagaga cagagcattt 8580 aggagtagag tcttggttaa ttgacaatga tacagggttt cttatattga tttataacca 8640 gtataagaca gagtttgttg ccttagaaca agtgttagga attgaggtct tagaaattag 8700 aacaggagtg atgtataatg tttagagtga cgtacattag ttggcgtatg aagtatgagg 8760 aatgtcttat ttttgccaat gatatttttg aggcgtgtga gattgctgaa cacttacagg 8820 gtgtagaacg cgttatagaa gttgtgaggt tggtgctatg ataaaaaagg gtttagagtg 8880 cattgtgaca ccgtgggata gtgattgtaa ctttaaagat ggtacggttg tgcgtgtaat 8940 tggttttagt gaatggagcg cgtggggttt cccacaatta tatttatgta cagatggaaa 9000 aacagaggga tattgtctta ctaaagaatt acaagaaatt tcaaaaaagt agttgacgtg 9060 ttttgtaaac agtggtaaca taataaatgt aagataacta aggaggaaaa cagatgaaaa 9120 acattatagt tgacggagaa acatataata atgtactaga agtaactatt ttaagaggta 9180 aatattcgga cgtatatgat gagtacgcgg gttgttttgc atatgtagat aaggaaacag 9240 acaccatttt tattgactac caataccgta cacctctatt gcactgtgac gttgatggag 9300 aactaatgat tccgctattt gcaagtgact ttgattatgt tgttaatgag agacatgagg 9360 ggtaaagagg agaggtcacc atgaatattt tactagaaga aactgtggca tttaatttgg 9420 gactgagaga cgccatcttt attagggtgt cagaacttac aaatattgta agggaacact 9480 tcacaactta cgtatatagt ggcatgcttg ttgtctccaa gttagagcaa ttggatgagt 9540 tttctaaatt gtcaagaaaa cacggagaag attatgcact tggaattgtg ctaggctatc 9600 cgccagagtg tgtgaattgg tttgtcaata gtagtataga agaacatgta atttgtaaat 9660 gtgcagatgg tggctcattt agttttaagt gtccagagcg tttgtttgat tatgcaaaaa 9720 cctatatgaa agagtatcat aatgtagagt tgcattatga tactaagtca gaagatattt 9780 ttgttataag aaatgatatg ttcctatggg aataatgtct aataaggagg aaaaataaat 9840 gattactgta acgattaata aatggcgaaa agcaaaagtg acacctgtta ttgttacagg 9900 tacagtagaa ccgcctgtag gtaaggagga gttactcatt ggacgtgagg cattgcttga 9960 cttagaaaca gatagcattt acattgaggc tagtgattta acttgggtat tccctacaga 10020 cattaatgat aaacgttacg cttcattttt cgcaagtgat ttcacttata aggagagtga 10080 acctaatgtc caatagatgg gaaacgcctg agaaccttga taaagaggat aaagttctat 10140 tacttcgtga acgtaataac ctcattagag aaaacgaaat gctaagggaa aagttgttag 10200 acgctcgttt agaggtagac gagttagcag atgaggttga ccataaaagt caacgcatag 10260 ctgaactaat tgaggacaat gaggagctta ttgaggaaaa cgcagaactt agtcagctaa 10320 ataataacct acgtggtcag gttgaatttt tagataagga agttgatgaa ctcattgaga 10380 aaaatgataa attaattgat gaccttgatt ctctatacga ctacgtggac gagttaaacg 10440 atttcataca aacattaatg gaggactact agaatgaata aaccaagttt aggactatat 10500 gttattattg ctttgttgtt tggaggcatt ggcttacacc gtatgtatga gggaaaactt 10560 ggctcaggtt tcttgttcct attcttattt tggacgggtg taccagtggt tatttcatgg 10620 attgacatta ttacagcact aacaacgcgc agacacttat tttcatagga ggaatagtat 10680 gggacgtcaa tacaaaaagg gtgacatttt aacatatgta gggggtgaag atgttttcaa 10740 aggtaagact attcaattag acactaagca gggctactgg tggggtacag taggtgataa 10800 tgataacctt tataatgaag agtacttaga tgataattac acttttatta aaaatgtgct 10860 agaaactgat aagccacagg ctaatatggt gaatgaagaa ctgacagata cagcacgtta 10920 ttcaaccaat tcaggtaaac aattgtttga cgtcttagca gatgacctac taacagatga 10980 ccaatatgag ggtttcttaa ttggtaacat ttataagtac attaaacgcc acaaagaaaa 11040 aggtggcatt actgaccttg aaaaggcacg tgtgtattta gatacgctaa ttaaatttga 11100 ggaggaaaaa taatgaacat tcatactgat ttacttattt tggctgtaga catgaacaca 11160 ggtaaggcaa cgggagcaat agagggggaa ggtgagaacc taaacaaaga ggaaacaatt 11220 gagctattag aaggggttgt caagttctta cgcgaagaac ttagtatgtt agatgaggag 11280 gaaaacgaag atgaataact atgagttatt agtagaagtt gaaaacacag accgtatttt 11340 aattgattta gaaaacgaca tgcgtgagca aggtgttgat gaccgaacac tcacattata 11400 tgctaactat gcaatgctac aggtggcaca acttctaaaa cttggttatg ttagtataga 11460 cgagtttatt gaaaaggcta gagaggaatt ataggaggta actgcttatg aaacttgtaa 11520 atatgactaa gaaaactata cctacagaag ataacttact ccattcaata tgggtacgcg 11580 aatatggtgg gtttttccta ccatctaatt taatgggtgg atgggttctt gttgacatga 11640 atgaccctag caacggttat aatggtagtg gtgacggatg ggttacagtt atggaaatgt 11700 gggaacaatt aggtaaccag tttgataagt tgctaccagt tgacacatta gttttacagt 11760 ctgttgacat tatggatgtc tcacaaaatt aacccttgca taagcgaggg ttttattata 11820 tactagtgaa cgagggggat gaaattaatg aacactattt tcacaccaac taagcaacaa 11880 aaagagaacg cgcgtaccat gtttgaactt tggaaaacat tagaaggtaa cgccatgagt 11940 tatgacccca tgacaggggg aataaaagag gttgttgtta cagagaacat tgaaacacaa 12000 tctaaaaaag gtaacccaat gagacgcctg aaactccgtg agacacgcac aggtagggag 12060 gctgtttctt acttaatgaa ttggaaacct gattttacac gttgggagga cattgagcca 12120 ctatcagtgg tgagggtaga cattgagtta aaagatgggt tctataattt aggtaagcct 12180 gaaattgcag gcaaggttga tgaagttcca ccgcgtccca ataaaccaag cgggaaacaa 12240 tatttagtaa tttatgatat tgaggtattt gagcaagatt ttgtcatttg tgctaaagat 12300 ttgtttagtg gtaaacgttg ggaaattgtc aatgacctag acaaggcgcg taaatggtat 12360 ttagaagtac gtgacagtct atttactggt tataactctg ctagttatga taataatgtg 12420 ctccgtggtt atttacaagg taaagacgcg tttcagttgt cacaggctgt tattaagtca 12480 gatgatagag gacttattta taaactcttt aacacgaaga aaactcctat tctaggttgt 12540 gacctgtacc atgaacacaa agggttttca ctgaaagaac atgagggttt catggggtta 12600 gaagtcaaag agacggatgt tgactttgaa caaggcggta aactaacaga tgaggaacta 12660 cgcaaagagg ttgcttattg ttggaaagac gtagacgcca ctgagctacg cttctatggt 12720 tgtgttgatg ggttacttgc taaagcgttt atttgtgcca tgttcaacct tgataaacaa 12780 gcatttaacc aaacaaacgc taatttagta gctcaattaa tgggtgccaa ccgtcctaat 12840 agtgtacgtg atgaccttac tgaaccattt acattacctg aaaacattca tgtaactata 12900 ccagagatta gagaaatgtt tttagaccat gagtttgacc taaataaaaa aggtaagccc 12960 gtagctaaag gaacgtatac tgaccctaat actggttatg ttatggagtt tggcgcggga 13020 ggtgtccacg gagctgttga acagcttatt cacattggac gctttctcat gcgtgactac 13080 ggtagtttgt accctaatgt gtatgtgaat tttgatgttc tttctcgtaa cgtacctgag 13140 gagaataagc acctagtgaa agaactctta gataaacgtc tagaggctaa atatacagat 13200 gaaacagaga ttacaatgaa cgaagtaacg ttaccaatgt atgtgttagt aaatggggta 13260 aaattgccta ttaatacatt gtttggtgcc acaggtgcag agtttaatgg gttatatgac 13320 ccacgttttc aatttctaac atgtgtgatt gggcaattaa ttatggctga cttctacgag 13380 ggaattaggg accatgttac catgttacag agcaacacag actgtcacgc ctacattcct 13440 catgatgagg aggctgaacg tattacagac gcgttctgtg atgacatttc tgagcgcgta 13500 ggtattgtat tggacaaaga tgagttcatt gccttatacc agaaagatgt caacaattat 13560 attggtattg acgctaaagg taaagtaaag gtgcgcggtg gaataatgct tacaggtggg 13620 ttaaaatact caaaagcagt tgtctctaat gcgtttctga actacgttgt tagcggtgta 13680 gattacaaac aatatattgc tgaatgtgat gacctgcgtc aatttcaaat tattactaaa 13740 acaggttgga cgtttgacaa gactgtatac gttgatagtg atggtaatga acatgacgca 13800 cagaaagtaa accgtgtgtt tgctgtgaaa acgggtgata aagctgttaa cttattcaaa 13860 gtaaaaaccg gtaaacttga accagttgaa aatgaggacg gagaacttga aacagaagaa 13920 gtaacctata ttaaaggtga tgactcatat gtaacaggtc taaacaaccc ccctcaatac 13980 tataccattt ccaatgagca gattggtgaa ggtgtacaat tagatgaaat tgaccttaat 14040 tactatgagt tagaagttga aagaacctta gtattatggt ttggtgagaa ttggaaagaa 14100 cggttgaatg aagcacacgc ccaatataat gagctgtatg gttcactacc agagccaaaa 14160 caatacgttt aatattgtaa atttttacgc taaaacgctc agagagcgat tctaagcaca 14220 tttcaaaaag gagattgtac gattaatgat taaagttttt tcaaaaagca actgtccaca 14280 atgtagaatg gttaaaaagt ttctaaacga acatgagtta gattataatg aggtaaatat 14340 tgaggaacaa cctgaggcac gtgagtattt aatgaacatg aacctcaaga cggtaccagt 14400 cactgaggta gatggtaaat taatattagg ttttaatgta cctgaactaa gacaattgat 14460 taaataaaaa agagacctat ataggtctct ttactctttt acagaggttt tatttagaac 14520 gagttcacta tcactcaggt ttggcgtagt tgggtcagga attaagttta ccgcgttgac 14580 aaaggtcaag gctaaaagat acgggttaga taccacagac attaagaagt ccgttaaacc 14640 ttgccatgtg cttaggtcct gaggttctag cgctaagtat gctaaagcgg gagtaattac 14700 accaatgatg aatcgtaccc agaataagat attgtccttg ctaaacctca cgcgccagtt 14760 aatatttttc atatgtcagt tcccctttct aatctattat atcatatatt taaccagtga 14820 tgaatgccaa aattgcaccc actacaccag tgataattgc tcctacggtt gttctagtaa 14880 gccatgtgtt acgtgattct agctctttga tgtcgtcctc tagtttgtta acatggtcaa 14940 ttgactgcga aagacgtttg tctaggtccg cgatttgttg acgggcacca gacagctctt 15000 ttttaatctc tctcacgtcc tctaaacgtg cgtcaatacg ctccatggtt aattgcattt 15060 tgataaagtt gtcctcattc attggcattc gttcccgctc ctaactttga ttgtatgcta 15120 gtctatttat cattttactc atgtagtcaa cttggttctg taacgtgtct actgcgttat 15180 cttgagtgct atatccgttt agttcataaa tgaggtcgtc catggctaac gcgttgccat 15240 ggaactcctc ctctagaact ctgttaaaca gcatatttaa ctcatcatca aacccattac 15300 cgtttaatac cttgttaata tactccgttt taaattgctc taacataatt atccccctta 15360 gaataaatct tgacccgcat atacgcaaga gatgtttatc catgcgcctg acggaatcgc 15420 actatctact gtagtaccat acctacttac tagaattgca ccatccttgc gcacttctag 15480 tagtagcctg ttcattccag aaccttgatg aatgagtgtt acgttattca atggtctagc 15540 ccaaactggt agaggttggt taatgacata ttgacctgcg ctaagttggt ttatgggttt 15600 aaacgcacct gctatttgaa ccgttctacc tactcgcgtg gctgtaggtg tgttagtgta 15660 tcccataaca tcactatatc tttgccaacc tgacgcaggg tccaacatgg ttgtttcaac 15720 tttaattaaa tcatgaattt ccagctttga gttacctaat gaaacgcgcg aatctgttag 15780 acgcaaacct gtactactat actctgcacc gtagccattg ccaccagagt ttgggttgga 15840 actgaatgtt tgtagattta gtgcgtcagg gtctagatat aattgattgt agtttgtgtt 15900 acctgcttca ttagttgtag ccatgagtat atagtttgct gccataattt gacgatgtgc 15960 gtttttaaac actcctgtgc tactgtactg ttttatattg tttttgattt gtgagttctc 16020 tagtgtaatt tcacctgagc cagttgagtt atctgaatat ttcacattgt aagggtttct 16080 gatggtacta cctacaatct caaccccact aactttttta aacatcccgt tttcagcaat 16140 aacattgtct gatacaatat tattaattga catcccccag ttttcccacg ctgtaccgtt 16200 ccattttagc acagtagggt cattaggttt ttgccataat gtccctgtag ttgggttact 16260 tggagctgta gcactaataa aaattgagtc tctacccgtg tatgagctag ttactaccca 16320 atttgtatac gtaccatttg aaagcgtatt tctactcctt acccacaacc acataccaat 16380 ttgaggtgtt ggacgtgttg tactccatcc tgaggtaggt tctacagaac tagttgtttg 16440 tacatactct gattgagtac cagtcacact aataccatcc tgaccaaagc gcgccactga 16500 gtaggttgtt tggttactat tatctgtaaa tgtccagata atacgtgtcc ataggtattg 16560 accacctgtt acatttggtg gtgttgcttg ccaacctgtg gatggtgctg ttgtacctga 16620 ggtacctaca gcgtaagtaa cagcgataga tttcacacca ttaccggttg agccatctac 16680 aggaatatag ttcactgtat aggctactga tgttgtacca tcagtgtact cccacgttgt 16740 acgtgtccat aggtatttac ctttttctag agttgggatg gttgtactcc atcctgatgt 16800 aggttcatca acgcttgagg tattgattgc ccactctgtt ttagttgatt tgacagaggc 16860 gccattttgt cccgttgttc tcatccacgt gtacttactt gggtccgtgc taggttcttg 16920 agtatagtta ctatattgac ccatatatag cggatatgcg ttcgcgaaat cttcagatgg 16980 gtttggggtg tagatggttg ccgtgtttcc tagttcgatt tttatttttg ttatagttat 17040 aattaaagca tttgaattac cctgtatact aaaagcatta gttgcccctg cggttatacc 17100 ctcaaattta tacgttgaag gtgtgtcacc ttgttttatt gtttgccatg tactgagagc 17160 gtcaaaatta cctaccctaa ttaacccatt attgttgctg aatgcgtcta ttgtgacgga 17220 atatttaact cctgctggca agtagttggt taataagtca ttgctataat agactattct 17280 gttagttgat gagtcgttaa acaacactcg catgttcccg tttgaatatt ctatagtcgc 17340 accatttcct gtccaaccat taatagtggg gtctttcgag aaatcataat tcaatactaa 17400 attatcattt gggtattgga gtgtgaacct ctcttttcca tcactactcc atgcgtaagc 17460 tgtgtgtaaa aatggatttt gaccatcctg tacgtttgca atactcaatg gctttgactc 17520 taatgccatg ttttttacct cctctaataa tctacagaac aataatatgt atatacattt 17580 gattgtcctg catttactgt gattgttttt cctgttgctg tccatgatgt gtctaatacg 17640 tttgaggcgt catatctacg ccatacaaac gaagtaaaat tatcagtaat gtcatccttg 17700 cctttgacaa ctttagctga tatactgatt gtaccctcac catttacaaa aaactgttta 17760 gacggtgtaa taattacctc agacggaata ctgttgtcaa actgttttga aaaatctgac 17820 gctatctgta gcaactgagg gtcaatacct gaatattgaa tacgaaaatc acctaatgtt 17880 aatgtgacgg tatcgtctgc gctacagcgg tcaattgtta gagctttacc tgatagatac 17940 aattcatctt tttcatctac aatgtttatc ctatcgccta catttaaatc agaaggtaca 18000 ttgactacgt ttacttcata attaaaagca ggttgacttt tctttttcaa ttcactaaca 18060 gcaagtgaag ccaatttacc tttatcaagg gtgtcatacg ttacagcacg tgtgaacaaa 18120 cctcctgttg ttgataagag tctggaccat ttaggagctt cttgcgtgtc aatcataacc 18180 ccattctcaa gtttaaaacg cccatctggg tcaacccacg agaacccact taatgtaatg 18240 gggttgtttg acccctctgg tgtaccacct aatgctcgta ttgctgtagt taactcataa 18300 atgttacctg tagttacgat tgaatctacg tcacgcccaa cacgtagagt aatatctttc 18360 tcgtccccca tatcctctac aatgttcatt gttttacttt ttaactgcat gttttcaaac 18420 tcaaagtcaa tggtaaactt agcgcctcca aagtctgaaa taatactcct tagacgctcc 18480 actgctgttg tctcattatc atagtttaaa gtacgtgtct gattactaaa gtagtttgcg 18540 cccaatgtaa agcccgtgtc tctcatgaca atgttccagt agtattgaaa cgattgaggt 18600 gacgtggttt taatagcagg tacaacatta ttaagtaagt caagtgcacc atcttcacaa 18660 cttatctcac gtgttcccgc caatgggttg tgtgtgaagt ccatgatagt aagacaggca 18720 ctatctccgt tatgtcgtct ataaattaga taattaccca actgcgccat ttctttaact 18780 ttaactaact gctcttgtga ttcatcaaaa tgtaataccc ctgtgaactc tataatgtca 18840 tctgtttcat agttgattat ctcatggtca tctgacattt taatgagtcc tgctccatct 18900 gtggacgcaa ttcctatagg gttaaattcc ctatcagtaa aataaaattc tattttaaaa 18960 acccccctta cacttgtttc tttattaatt ataccataaa aaagccactc tttggcgagt 19020 ggctagatgt tattacaagt aggttcgttg gttcttcaca gttacttcta aagtgtctgt 19080 agcccaatct gagttaatga actgtaggaa atgttctcct acatcaagtg cgaagccttc 19140 ccactgattt cctatggttg ctaggtcctc acgttctaca ccatttacaa agaaggtttt 19200 atcatgtgtg tttatgacaa tcttgtcccc tgctttaaat gggtttttac tttctttaga 19260 tttacctgtt cccatccatg tgaatcttga atctgtcacc tgcatttttg caacaataga 19320 gtaggtctct ttcttcttgt gttccacacg tttagtgttt tgtaggtaat atccactgac 19380 ccatcctgag gcaggtattt tcttacctga gttcttagtt acataatacc attggttgtt 19440 tttaataatc ttttgacccg tttgacgttt ggttgtttca aacgtgacgc ccttaggtaa 19500 cagaccgtat gacttgtaac tagtcttgga acctgcacga atgtgtagga cttccttaga 19560 tttcattgtc catgttacct tatccactac ctcccttgtg gctactgagt ctttatactt 19620 gagtagccat ctagatgttt taacaacgga agctttgttt gctacaggtg cattgtaggt 19680 aaatgggttt tttgtaactg gtttaattcc gttgtttgat tggatatgct caaagttcca 19740 agtgaacttc ttacccgttt ggtcacgtgt cattgtacag cggaaccaag atgatttgta 19800 cttagttacg tctgtcttga tagattttag taacttgtta ccgtaccagt attcaacaat 19860 cacttcattg ccttttgcgt cagagtcacg gatggctata gacattaata tgtcattagc 19920 gtctgtcaaa ataaccaact cataacgtcc gttcttttct gacgtagtac cgaagtctat 19980 ccgttcctca aatttaaagg ctcctgttcg taaacctgtt gatggtgctt tgacaggcgt 20040 tgtaagggaa ggtcctgacc atgcgtttgg tgcgaatgtt gtagcccact taggtttaaa 20100 cgcctcagaa gggctgtagt cccatgaacc catgtagagg tttggtctag cagggtcgtt 20160 agacgtattt gggtactgtg atacgtgccc actattgacg gtgaaaccag ttggcaattt 20220 cgtacctctg tagttttcat ttagaccaat ttcgtcttta attggctctg tagcgtcttt 20280 gttttcttca ttgccaaact gtaggacttt accgttttcg ttcataacag caatcatacc 20340 gttttcttct gcgttggtga tttcaaagat tgggtaactt ttccacgttc cataattggt 20400 aacaggtaca gtctttagaa actccttaac agaagccacg tatgtcccat ctgtgccacg 20460 tgttagcatt ggtctgttaa taacaacgtg tgcattacca tatacattta ggctcaatct 20520 gagaacttta gtagcttcat tttgaatggt atatgtttgc gtggtgcgag tcattggaat 20580 tgtagacgcg tctagtcctg tgccaattga ataccacgta tatagtttac cacgttctgt 20640 aatgtgttgg atgaacgggg tagcatggtc attttgttct agtttaaagt tttttacgta 20700 aaacgtacct acaaacgaag ggtctataac aaacagcact tctatcttat tgattgcttt 20760 attttgggta gttatactag cagaataccg cacccagttg tctgtacttg tgtttgtgat 20820 tgagactttt ccatcttcgc gcgtactatc atagtaggta acacgcacaa ttaattctgt 20880 tgttgctaga ctaccagtcc accccttaga gatgaataca ctccctgata cagtgtacgt 20940 tgtaccgcgc aaagcactgt agccatttga taggtatgca ggacgtattg ttgacactgc 21000 tgttttagtt aatttagtgg ctcctgctgt tggtgtagcc gttactgcgt caaagattcc 21060 ccaatactgt atactattgt cctgtgaacc gtttaatagg atatttggcg cagtgtcctc 21120 aggtacagtg tccgtggtac tataccctac atatgtaggg ctagtattgt ctactgtagg 21180 tgtattaccg tctgtccact gtgtagcacc ctcattagtt gcctcaattt tagcgcgcca 21240 aattgtaata tcaggtaagt cccctgttgc gtcagagtag aaattaaacc ccatatctgt 21300 tgaacccatg gtgtaagttg gttcaaagct aatgtactta ctctcattgg gatatattgt 21360 tttacccact cccattctgt ttgaaataga aataggttta tcaccgttgt tttttacata 21420 tatactatgc gtgtagtttt gtcctatgat gtactgtgtt cctttaattt ctaacacacc 21480 tatgagatta ttacttgtgt tcttagttac cttataattg acagcattac tagcacccca 21540 ttctggtaca gaaacccctg ttgttcgtgt aaattcacta gttccgtcag acactagtgt 21600 tggttgttca gattgcccac taggtattat atttgggtta ggttcgtcat tgaatgagaa 21660 acggtctgtt cctgtttcgt tgaaagcgta tgcggtacgt acctccccat tggttggtaa 21720 aggtgtagta tgtgtatgca atactttacc gtttatctta tccatttcat caataacaac 21780 ctcaaaggta ctagaaccat catcatcaaa ctcactaacc tttggtatac cgtagttagt 21840 tgcaaacgtt acttgtgagc cttgggttag gtcatctgtt tcataaaaga catcatctga 21900 aacaaaatca tgaaccacta gacccatgtc ctcaatttgt tcatctgaaa agtctaatga 21960 caatacatta gaaccgtttc tctgcgtttc caatacagta gtagtatcag accaatatgt 22020 tttagtttga aattcactat ctactagcat gtttgtagat gtactttgtg tgtttctaaa 22080 tgggtcactt aaaatagagt gtgccacacc ctcagggcat gaaaatgtta acgtcaacgg 22140 tgtaatgtct aaattagttg cgtcatactc ttgcgtgccc tcaaacacta cgttaaaata 22200 tctatcaggt aatgcgtcaa acactagttt cataggttcc ctactcatta cttgtgcaac 22260 tagtaaatct tttgtctcac taatagaaag tcctgagtgt tctgtaatca agtgtccatc 22320 aaaagtaagc gtgttattgc ctattcttgt atattgtagg ttctgaccgt ctgaattacc 22380 cacttgataa tatccgcgtt ctacatttag gaatggaatt gttacagtac ctaccacaaa 22440 taactcacca atatctacac catttaatgt aaagtttcgt aaaaagacag gctgtgccat 22500 cttataacct cctcataatg ttctcattct attataacat aattctaatt aaaaaagttg 22560 atgacagtca ttgacaaaat aaatttaata tattatatta ttagtataat cagtataggg 22620 aggaacttca taatgagaaa agagttgaaa aaacacatta agcagatgaa cccacaagag 22680 attgtaactg ttgtgaatat ggttgagagc gctacaagag gaatgtgtaa agagacaatt 22740 aggactagtt atcattgtaa agaacgtatg agtaaacgtt tgggtaaagt agataatagt 22800 attataatgg atgttcttag tcattatgaa gttattgagt acaagcaagt ttttgatggc 22860 gcctatatga tagacaagag agttgtgtta cgtagcacaa aagcttatac agacgaatac 22920 aattattgta ttgtatttag tttacttaaa aagtctgtgg taacatattg gaaaaataag 22980 acctacaata ctcatgaaaa tgtagactta agtaaataca acgtaaatat gaaagtatac 23040 taaaaaagag aggtataaac ctctcttttc gtttagctaa atgttacaaa tacttcaccc 23100 gttttatggt cacgtacagc catgtagcgt gtacctttat ctgcctgata gcgtacccat 23160 gtatagcgcc catcataagc ccatgcgttg tatttaatcg tatatccttt aggtaattga 23220 cctgtgattt ttgcatttgt tgacgcgctt gcacgaacgt tcatgacgcc tttagtagta 23280 gccttagcat tttcagttgt ccatttaagg actcctgacg gtttagagct attacccatg 23340 ttagatgacg ccgtgtctag gtcttgtgct aagaaccatg agttaatacc atcaacaaga 23400 aacgcatatt tacttacaga ttgattaact gttttacgtt cttttacttt gtatgtttta 23460 ccttttacaa agtttggcac tggttgaccc gtttggtatt tagttgcttt ggcgcgtact 23520 tttactttac tacctacagg gaaatcacgt gtgtctgtga tttttggttt agacggttgt 23580 ggttttggtt taggtttgtt gtcagtattg gaactatttc caccaaaccc atttttaatg 23640 tctttagcaa actgctcttt actaattccc catttacgca agtatggata ggggtcaata 23700 tggtcagaac cattgtttgg ttgatgtgcc gttgcatatg cgtgagaaat gacacctgta 23760 ttcccttggt ctagcgtctt aggtagtccc gcttcatcac ataatagacg aattaattct 23820 actagtagct tatagtcttt cataaactct tctttggttt tgtgcgattc aatcaattca 23880 attgccgcat atccccacga gttccatccg ccacctacgt cataaaagcc cgcgtttgtg 23940 cgtgctgttt gaattactcg cccgttacct actacgtgcg agaagaaccc actgttgacg 24000 ggtctgcgca tatgatagtc tgcctcgttt tgcgctgtag atgatgaatt ccccgtactg 24060 tgtacgtgaa tttgtccata cggtcttacc cctacttgtg gtaaacctga gcgcatttgt 24120 ttttcaattt tcattgaatc attctccttt ctatctctaa tcattataac acaaaaaagg 24180 aggcttaagc ctccttaggt tatgctaaac gcccttgacg tctgttagat accatttgtc 24240 cgcgttgctt atctttagtt aaagcagggt ttagttccgc agtaacttta cgtttgtcta 24300 agtagacgtc cgtgtccttt tctagtaatg cttgtaacag tgcgtttgtt tgttgttgct 24360 gtacaatcaa ttgagcaatt agctcatcat tagaaccctg accagctacc acggttgttt 24420 gtgatacacc taaccgcttt tgtgcctcag ctagtagata catagcgcgt gagcgtttgg 24480 ctttgtctag tggaataacc atttcaggtt tattaccctc tcccaccata gctaaatgtt 24540 ctcgtgtgat gagtccaccg ttagcataac cagtaccgcg ccatccgcgc gttagagaac 24600 cgtaacgggc taaagtatat ctaattgacg ctaaaatgtt tgataatggg tcataaatgt 24660 ttttattgta tggtttcatt gcatattgtc tgaatgtagg gtcaatcacc tgcattagac 24720 cttttgacgg aataccattc tgagcattaa tgtcccatag gttgatagct ttggggttac 24780 cattggactc tgtacgcatt tggttcatca gcgcgtttag gtttgcggtt gtccattgtc 24840 ctgtcatctg taaggctcgt ttagcagttg cacgccaacg gtctacccct gaccctgttg 24900 ctgtggtgtc aattgctcca ccttgtgact gagggtcttt cacaccatta atgtgtaagt 24960 ggtccatgtg tccacctgac gcccaattag tccatgtgtc atgaataccc gttccagatg 25020 tgcccacgcg gtcacgtact ttattcagag caataacgta gccaacttgt gatttaaagt 25080 tatcaaaagc atagttaccc gcttgacggt atttacttga cccgttcatg cttgcaggaa 25140 atgctacgtc aatagcgttt cttgaaccgt gactatatgg gtctcctggt ctatatccac 25200 ttgttacgcg cataccaggg tatttggcaa tcaccttacg cgctacatta gtaaggtatt 25260 tatacacacc cgctgtacct acagacgtat ctaggctccc gctctcaaac gcctcagtaa 25320 cacgtgacgt aagagcgcta gtagctttct taatcattcc acgggcaacg tctagaggat 25380 attttatgag acctgaggtg tctactacgc tagagaatac tttttcaact aatttgcttg 25440 ggttagttgc gtagtcccaa acgtcaccaa caacactgct aaccttatca aacgcacttt 25500 tagccatgtt tttggcaccg ttccagatgt tttttacgcc tcctgtaatt ttgtcaaaga 25560 agccagtacc ttttttgtat gcaaacttag gacgtttatg acctaacact tgtgcagttt 25620 cttctgctgt taaaacgtgg gttccttttc gtccccacat cgttacgttc ttacctttag 25680 ggataaccgc ttgaccactt gggtcaataa ccatttcagc accacgtcca tcattgacag 25740 tcatgggacc atctacaggg tgaccgccac ttggtgtacc tttggcgtat tcaggtgcct 25800 cccatgtttt taacttgtcc atgcctagtt tttctaaaac ccagtttgca ccgccaataa 25860 ttccgttcac tggtttttca attactttca aggctccgtt aaacatacct ttgaatgcgt 25920 cttttaggaa gtgagcgcct cctttaattc cgtcccctag tttcttaggc agtcctttta 25980 tccaattgac aactgtgtcc ataccaccgc taaaagtacg ttttacaccg tcccacaagt 26040 tacctataac acgtatgaag ttgtctttga tacctgaaac gccttttcca atgtttgacg 26100 cccaaccttt tacaaggttc catgcgttac ttgttcctgt agtgaaaaag tttttgacac 26160 ttgtccacat accactgatt gtattaccaa aaccagaggc aagtcctttg actcctttta 26220 tgattttagc aaagaataga atttgtaacc agttccagat agccttgatt gctcctgaga 26280 atagttgttt gacaccatcc cacatgagtt taaaatcacc tgtgaatagt ccagtgaata 26340 tttttataat acccataaca gtgtcaacca taccttgaat gaacccgata acattgttga 26400 caaagtcacc aactaaacca attacaattt ttagtagtgg actaataaaa ttaaggaagt 26460 tcatgaacgc ttccatgatt tgtttaccat actgattata gaactcgctt acctgtttga 26520 aaatgctacc gaacgcacta aaaatcgtgt ctagtatggg ttttaataat ggataaacct 26580 tttcaaacat gatggcgccc atattccata ataactccgt gatggtttta atataatcgc 26640 caaccggttc cagtattggt tgtaacttac caaacacctc acctaaatat tgccctactt 26700 ttggtaagat gtcttttgta aagttttcaa tagtatcagc cattgtgctc atgataggga 26760 gcagttgcat gcctacttca ttttttaatg ctgaaataga actactaaat gcgtcccaac 26820 ccgtagtgtt gcctgctgaa tcgacaaccc catcaatggc accctctacc tcagtgaaat 26880 tgttttcaac ccccgcaagg gctttaatca ttttcatact gttgtcctca cctagcgcgc 26940 tccacactgt agaggctttg ttaagtgatt cataactaga gtccattttt gagaagtcgt 27000 ttagcatact ttgagtaaca tcagcctgtg tcgctttgcc gtctttgaat gcttgaaaaa 27060 cgtctcttgt tttctgagaa aacatatcca tgttgtcatc tagccgtccg tcaacaatag 27120 agataccaat ttcttttact aggtcgttca ccttatcaag gttatatgct ccaccgtcaa 27180 gacccgcaag cattgtacta aatgcctcat ctgctgtata tcccatttgt gcccaaatag 27240 gagcatactc cgctaagtta tccgctagtt cgtcagattt attaagtccg ttttgtgcgc 27300 ctaacgtcat taggtcaaac gcttgcttac tatctagacc ccacgagttc ataatggcgc 27360 ccgcaccgcg tagggtttca tttacgtctg tatcaaacat ctttgaaaac gataccgcgt 27420 aacgtgtaag gttctgtagg tcctcaccga atacagggat agggctgttt tgctcaaccc 27480 tactcatagc gtcaaccatt tcctcaaggc tacccaaacc ctcagcaact agttcgttag 27540 ccatttgagt gtagttttct gcgccctctt gtgaaagacc taatgcacct tgaaacttat 27600 tgatggcgtc ttttgattca ttgattccgt ctgttagacc cgcaaaagtg cccactaatg 27660 aggtgaccgc accgattacc gcgccacctt ttagagacat tacaccatct aatagtccac 27720 ctaccccatc tgtagcctcg tctgctccac ctttgatgtc actaagtcca tcactagcgt 27780 tctccattga tttaagagct ttacttgata atttagcctg tgactctaat ttagataggg 27840 agattctagc ctcctcaact tctttagagt tttcaccgaa ctcctgagaa ctcatttcaa 27900 tagcgcgctt ttgtgcctca atagctttct cagttaagga gattgaacgt tttagaccct 27960 cctgtttagc ctcaagtgcg cccgctgagt cccctgcgtc ttttagtgct tttacttgtt 28020 gttgagtctc acgttcgttc tgtttcattt ctttagaaag ttgtgttagt ccactcttag 28080 cgtcaatgta ttccttggag gttttttcta gttgactagt taaaccattg tattttgctg 28140 tggcgttatt gatttgagtg cttagagact gaacctgttt agactcagcc ccgtatttct 28200 ttatagcgtc ctctctacgt ttgtttaaaa cctcaatgcg tttctcttga atttttacaa 28260 cgtctgttaa gtcgctgtac ttttgttcca atgcctctac actatcagag gcaccgtcaa 28320 acgctttgat gtttgccttc atggagcttt cagcttgttt gaattgtttt gttagtttgt 28380 caagtgtatt acctagttca gcggttccgt caatacctaa accaaacttc atatttccta 28440 ctggttttcc gctttgcacc atgtgttaat cagctccttt tttctctagc ttttcaagtt 28500 cctcaggact taagaaacgc ttaataaagt cagcgccatc catcaccttt tcttgtttag 28560 actctttacc aaacaattgt aataaaagaa agtagtcagc gttctctatc tctgagagtt 28620 gccagctact ttctaagagg gatgaatatg tttcctcaag ggtttctaac tgttcctcaa 28680 aggttttttc ctcaagtcct gttatttctc ctttgaaact gtacccccgt tgacttgttc 28740 aaagactccc tgtactaatg gtaataagtc ctcaaaggct acgttatcca ctaacatatc 28800 ataagtaagt tttgtgtttg agaaaatgga gagaactaag tttagcatat catctaaaac 28860 ctcaatctca ttcatttgta actcaccttt ttcaaccttt tccattttac tgtagtatgc 28920 taaaatctcg cgcattgttc gtacagttac tttctccgct gtaaatgttt gttttttacc 28980 ttttactttt agttctaatt taatcattat aattcctcct aatatgttat gttctattaa 29040 tattatatca tatagcgcac aaaaaaagag gggtattacc cctctttact gtccaactgg 29100 cgttgttttg tttgctacaa agtcttggaa tttctcaagc gtcaacgtct cagacttcac 29160 accagaggcg tatacatatc cacgtgagtc actaatagca gacccctcaa tagtatcagt 29220 attagggtca gtgcctccac cctctgaggt attcaacgca acgtcagggt gagcaaagcg 29280 aactttagtc agtcccatat atacctcatt accatctgcg tcatctgata caaaagtaac 29340 agagacataa ggagcttgag tgtcctgccc cactgtcata ataccatttt cgtctgcggt 29400 aatacctaaa acagcactat atgctccacc cgcttgtaag tcgaaaacat tcaatgatac 29460 ggttgtttca cctgtacctt tagcagatac gaaaaacgga acgtttgacg cgtagactgt 29520 agtagcctcc gctcctagtc cactgattgt tgcctcaatt gcaccgcctt tagttttgtc 29580 aaggttgtag gttgtgtagc ctgtaccctc gttattgggc acatgaatat gagcagattt 29640 aaaaccgatt tttgccatgt ttgtgtcatc ctttcttgtc tttcttatat tattttaaca 29700 catgattttc gttcaaagtt agactagctt tatgtctctt gtgatgatat agcgtttaat 29760 gatacgtggt gcgttctcaa tatcagggtc agtaccaatt tcactatatg atagactatt 29820 gtagtttcct gaaaatagtt tgtccatttc atagtaaata ttttgcgcct ctgatagtgt 29880 cttacaccat acatctacct gtatggttat ctccatcatt agggggttat tacttgcata 29940 agagtcgtga gtatatccaa tctcagtaat tcgccctaat ggtaagttag gaattgtttg 30000 ctccgcctca ggaacaaagt ttacgtacca gtctatatct ggataggctt gacttagttt 30060 atccgcaatt agtgttgtag ttagtttcac atataacgcc tcctaaattc atcctctaca 30120 cgtttctgta catctttaga caatgcgtct aaagactttt ctatcacgtg ttgaggtggt 30180 tgtttgatag ttccaaactc aataaagtgc gcgcgccacg caacctcatc atcaaagcca 30240 atttctacat atccatcttt ggctttgcta tagataacat ggtctctcat atgctcaccc 30300 atatatgaac cacgcttacc gctcattttt gctttactgt tagaccagta tggtacgcgt 30360 ttgctaaatt cctcagcaac ctcaggcgct atgtcgttca ttattttatt tgcctcacgg 30420 tctaagtctt tacctagttc accaagcgct ttgtagatgt cactaaagtc tacataatta 30480 tcactcattt taccacctca tttaaaacgt cctctttaga aacctcctta gcaatcaaag 30540 tatcaaagtc tttgctgtat gttccacgtg aaacatcctc aatgcgatag cgtacaccgt 30600 tgtgtaaaat ataatggtct cgctgaatct gtttcttttg gtcatacctt acaatgaagt 30660 taacagcgtt ttctaaagtt gtacccgcag tctttacttt atcacgcata tattgagact 30720 caaaagacgc ccaacaagat agtaagtcct catagattac tgtaggttgg taattttcgt 30780 ctttaccttt tttggcgatt tgaatagtaa tacggtcttt taacttactg tattttctaa 30840 aggacataat tatcaaactc ctcaggacgt ggtaagcctc gtaattgatg aatgagtgct 30900 gtcactccaa acggaatctc agacaattgg ctaccgctta ctccctctct attttcatac 30960 cagtgggcaa ttagaaacat tgtagcaata tcaaagcgtg ggtccgttgg ttggtccttt 31020 acctcaatgg ctcccatcaa aaaagaaact gctgtttctt gtaacattgt taaatactcg 31080 tcatccatat tatggtcaat gcgtagatta tttttaattt ggtcaattgt tagcattatc 31140 tcactcctat ctaataaaaa agaggtaaga ggttttaccc cttacccctc aatgggttag 31200 ttattaggct cctgctccac cactagggaa ctcagacgca tttgctactg ttaccgtaga 31260 aacgttgtta ggaatagctc ctaatttgaa cattaagccc gcctttgtgt ctgtagctac 31320 tacgtcaaaa cggatggcac ccgctaacat ttcaccgtag acattgtggt cttgccaacg 31380 taccgtcatt tcagtacgtt tgaacaaagt aatagcttgt tctaagtcac caatgaataa 31440 tagtttatca tttgtgtcgt ttttaaagat agcgtcagga agtacaatta cctctttacc 31500 aaacaatgtt ttaccacttg ccattgctac gtttggttga ataatgtatc gtccgtctgc 31560 gtctttcaac gtatccaatt gagcaaatgc gctttgagaa acaaaaactc gttgattgta 31620 agcagggtca attgttacgt ttgacgctgt tttcaattga tcaagagaag ttacttctgt 31680 tgcttcgaac ttagctagta actcagtcat tactgcttta ttgattgtgt tcaacccaat 31740 acgtgttaag tggcgagcaa tcaacgcaac taagtcaggg tcagagtctt gaattgcttc 31800 gttagacatt ggaatatatc cgcggtgtgt ttctaccttc cattctacat ttttgaatgt 31860 tggttctgcc aatttagggt tttctactaa ctcagctact gtgttcatta ccgcgttagt 31920 tgtttccaaa atagggtaag aacctgacgt tgtgctaact gttactacgt tgatatagtt 31980 ttgtaggtct acgattgtct caggtaatgt tacaggttga gtaatgcggt caaccggaac 32040 aattgcctca acgccctcta atttaatatc ccgtaactca ggtgctttta cagaaccgtg 32100 tgagcgtaca tattcaccga acgcacgaac ctcagcttca gcaacgtttt ctgtagggtt 32160 gattttcttt acattttcca tacttctagc ctctcctttt tctaatttgt ccacgtcttc 32220 ctctaatgct ttagcacgtt ccgcgtccac agatttatct ttattttctt ctggttcaac 32280 ctcgtctgcc tcatcatcct taggttgttc atccttaggt tgctcgtcag ggttaacctc 32340 gtctgtttgt tcgtcttgtg cctcacgaat ttccttgatt aatttatccg cctcatctaa 32400 tttaccttgt gcgataagtt cacgggcttc tagtaatcgt ttatccatgt ttcacactcc 32460 ttattatgtt tcttaaataa ttataacacg cgtttattaa ccgcgggtga gttagctgta 32520 tcacattaat tctaaaatgt caagttctaa ttctaatttt cttttttgtt ctttaaacgc 32580 tttttgtgac cgttgtgcca ctgctacagt tgtatcatca tatgcgggaa ttgaaactag 32640 tgaaatctct accaatctac caatttggtc aattgtgcgg tgatatgtgt ctgtgtttgc 32700 gttgtatgac cacgtatcac ttttaaccat aaacccaaac gaacactgtg ataggtcacc 32760 gcgttttact aactcataga cgtctctacc taattgggta tttggtaatt gtagacggaa 32820 ctttaaaccg ctgtcgtctg tgtttaattg tagggtacct gtctttgttc gtcctaataa 32880 gttacctgat tgatggtcat aaaatgcgcg gacgtctgag aagtcaaccc cattaaaagc 32940 atttgaacta atttgttcat atacgttctc atagaggttg gtttcactgt tgaacgtaac 33000 agcgtaaccc tcaacaatca tgtcctcatt ttcctcaagt gctctaatct caatgctacg 33060 cgtctccgtt ttcatcatta gtagcctcct tattttgatt gtttgtttca cgtgaaacat 33120 taatacgtga gcctgtcatt ctagaaaact gactctcgtc tgtttcagga taaccatagt 33180 aggcgcgtac ctcgttaggt ttaagatact caatgccttt ggctgtaccc tcaaacattc 33240 gttttttgcg ttcgtctaat gtatcgttta ataaactagc aaagtctagt tccacgtcaa 33300 tatttaattt aagatttaac tcatcacata tcattctcgc atatcctgat aaggtactag 33360 caatgtaaat agagttttgt gttccgtctt gtgagtttac taactccata ccaaaacgat 33420 ttaaaggtat accaaacact ttagctattt gttttgtgct aaaggtatta gactgaatta 33480 gtttcaatag gtctgtatta accgtaaatg tttcatactc ttgtgtgctg tccaatacga 33540 gtacactgtt tgcgttctgt gttcctgaat taatggactc aaaatctttt ttaatttggc 33600 gtttgacatc gttattcacg ctaccttttg ttagttttaa gatagcacca ccaaagatac 33660 cttttttaaa gtaactacct aacaaacgtg ttccgcttgt ttgcatatct atttcaggta 33720 ctagcgcttt tagtggtgag cgtcctgaaa tgccgtcaat tgagttcagt ctaaaatgta 33780 acatgtcttt acccttgatg gtttctttct tttgattgtc agggtcaatg tactcatatg 33840 acaattcttt actcgctgtg tcttgtaaga ttgtaattgt atgagggctg acaatctgta 33900 gcttagtaac ttgtgttccg ttgcgtctaa tgattgcaaa cgcagaccca tataaaaggg 33960 tatacatggt aatagcatac aaccaaccgt aggacgttag gtttgtatct ggtttactac 34020 gcaagatatt tacaatctga ggtttactta caattccatc cggtcgctct ctaatcaaac 34080 atttagcaat atcgccactg ataatgtttg ttgctgtgta aatgtcagaa ttttttaaat 34140 gttcaatctc gtctagtgat tgccctgtaa taaaagtacc aaagtccaca accattggtg 34200 atggtgctac ggggtataga tttgcccgct cttcgtgtgg cttgtttctg ataaaaattc 34260 ccattagtga ctctctcctt tatcgttgat gttatcaacc tgctctaatt cctttgatag 34320 cttaaaactt gtagccaaac aagcgccacc taataccata aaacctacgg ttatatctac 34380 caaaaaggca ccaatagcca taaaaacaca cgctagtata tacataatca taggtaaata 34440 tataattcgt tccatggtga acctcctcca attataactt ctttataaat tataacacga 34500 aaaagacaac cctagttggg ttgcctcgtt cgtttattac agtccaaaac caaaatcacc 34560 gcttgcgtaa cgttctgacc agtttatttc ctcgaactca taaaagtatg cttcactgta 34620 cgcgtttata agcgcgtcaa gagggtcaat cttgttgcgg ttaacttgtt tatcaatcat 34680 aattaaatcg tttgactctt ttgtaaatgc gttgtacacg gctcttgtca atagagggtt 34740 gttaaagtga aggaccttgc ccgctcgtat atccacttgt aattgtttag taggtgggtt 34800 taatcgcata taagactgac gtacatcaaa gagtacgtcc tcatacccgt ctgctagtct 34860 tgtggtaatt aattgagact gtgcagggtc ataacaaata ccttgtacgt ctaaattgtt 34920 tgtctcaata aacgccaaaa cccaatttaa catatcctcc caatcacact gaccgtcagg 34980 acgggaagaa atttcacaat acccctgttt ggaatattgt ctatagggtg ttctatcgtt 35040 agcctctttc tgaacaatac caccacccgt tgttgctacc cacgcgtgag agtcaacaat 35100 aaacaattct ttttcaggga taggaataac ccacgtaaca gcggtcaagt catttactcg 35160 tgctaggtct ataccaataa atacttcacg ccctgtgatg tcaaactcct cgtctgtgta 35220 cgccttttcc cactcgtcta cagaaatgta tgacgttgct tggtccgcaa cccaaaaatt 35280 aagctcctta gttaggaagt tggtgagatt acctttagcc tctccctctg tctttttagc 35340 ccgtttgtgt tctaacatat gtgtgcgaac gtcaggtttt tcaaaaagag ggttagattt 35400 aaaccagttt tcctcgtcat ccgcctcgtc aaaactatcc atttcccacc atagagctaa 35460 gtagtgttca gcctctacct cacctgttaa tactttcata gtcattggat attcctccat 35520 atgatagtgt ccgtttaggt tttgtgaggt tgtactaatc attaagttaa ggggttgtaa 35580 ttgttgtgac tgagatgact caataacctc aacaatagaa gtatctttat tctcagccat 35640 ttcatcaaag atggagcaac aaacatctaa cccatctaat acagatgagt ctgaggctag 35700 agctttacaa aaagagtcat cttttgtctc aatgtcatat ttgtttactt ttgtaaactc 35760 acgaaccttt ttagatttct ttctaacagc ctgtagttgt gtcttaatca tgcggaaaca 35820 aatagacgct tggtcttttg tattggctgt agaatatatt tgacgggacg ccattggcga 35880 acgttcgtaa agaagttcat ataatgcaat acccgcgatt aataatgatt taccgttctt 35940 acgactcatg gagattacca ctttagtaaa tcgcctgtac cctgagtcct ttttaaccca 36000 tgaaaatatc ataccaataa tgaacttctg aaagtctgct agtcctaccc tcttaccgct 36060 tttggggtct ggtaggttgt caatgaaagc gattggtttt tctgctaatt ctggtctata 36120 ttcatacgga aacgatgggt attttgacct ctctaagtcc cgttcatgtc gctcaatagc 36180 taactgaata cgtttcccta caggatattt tcccgccttt actttgtcaa tgtaaatttt 36240 tacatagtcc ttactcattt gctgtatcac tcctttgttt cacatgaaac attataacat 36300 gtcaccaaac gggtctggtt gttctttcgt tttcatgctt gggataatta atttcatacg 36360 tccatcaatt gaaagtccta atgaacttgc tagagacttt agttgtttag atgtttcatt 36420 cataacctta aaggcgcctg atggtttccc tttttcgtca agataaccgt attcagatac 36480 ctcttgagtt gcctgactgt aaatagcgta agtattacaa taaatgacta gcatgccagc 36540 gtctagtttt gaaattggta gctgtttaag ttgtggaaca aggtcctcgt aaatcaacca 36600 cccttcctta gtaattccct caggaatatc gtctaatgaa agttgttcat aattatataa 36660 ctcttgttct tcttgctcgc gctcaatacg ctcctctttt gttaaatgac tattatcttg 36720 tgcgctgatt agttttctag gtcttgccat gttactctcc tcctaaatat gtctttgttt 36780 caagtatagc ataaaaatat ttgttttagg aatcgtaact tatttttgaa tttaggtatt 36840 ttttactttt attaataaaa gtatttttta cctttattag tttaggtact ttttaccttt 36900 attacttttc attttaggaa ttttgcacga aaaagaggga acagcgatta ttttcaattt 36960 aaaaaggcac ggggggtatt ttttagagcg tctaaaatat ttctaaggta attataccca 37020 gaacacttag aacgtatctc agagcctctc agagcgtttt agagcatgtt tgtttttgag 37080 cgtaaaaaag agagggttat ttccctctca atttgtttct attactgttt ggatgttctt 37140 gtttgttgtg acaagaaaaa caaatacttt ctaaataatt catatctaac ctatgttccc 37200 atccctcaga ggttcgtatc tccgtggtat ggtgcaccat gtctgctttg gtagtgatat 37260 ctttgctcat acatacttca cagaatggtg tctctaatag ttttgcttta cgtgttgctc 37320 tccattcagg tgtgtgatag aacatattgt atttactatt tggcttacta tatcttactc 37380 tcctattgta ttccttaccg ttgtctcctt tgtgtatgtc acagtacatt gttcctacag 37440 gtaccttgtt cctacaatag gacacattac atttcttcat tggcataact acactacctc 37500 catccattgt tgtatcatgg tatcactaat agatacacca ttggttatac tgtcatatac 37560 cttttgttct atctcattat cagctaacag gtagtagtac acagggtcac tggtagatgt 37620 gtgccgtgct atccgtccct tcatttgttg gtacgtaata ctagaaaggg gtagctcgta 37680 gaataccatt atgtgggatg tagctaagaa gtttacccct gtacttcctg ccttgaattg 37740 tactagaata atcgcgtcct catgttgttc ccatgtctct aagtccttaa tagagccatt 37800 atatattgag ataggtctat cacctttaga caattcctct actaatctat tacacgtttc 37860 tttatattga tagccaataa caacgcgttc tcctttagtt tcttctagta tgtcttttag 37920 acggtctgtc ttgctgtttt tagctacttt acttacatat ggtataaaac cattagacgc 37980 aaccctaagt gcgttaaaca gcttgctagg gttatctaat tcaattatgt cacctgagtc 38040 tgtttcatat actctatgtg tgcgtagttt cttaaccatt gatggtgact tgactttata 38100 cacaatatct gatgggatga gtttgttgtc acgtttaata gcaacgctgt gttctttgag 38160 tagctcattt aattcctcag tgtttctata tcccacaatc gcattataag accgtccacc 38220 taaatactgt ttctcttcta tacagtagcg ttctctaaaa gatttccacg ttccagagta 38280 taaacctgcg attttcaatt gagaaaacca ttgttctaac attccgttag aaattggagt 38340 tccgctcatt aaataggtgt gtcctgcttt cttacttact ttcatccaaa acttagttac 38400 gtttgcgctc ctgtttgcta gacagtgaga ctcatcaaaa acaatcatag tgtctttatc 38460 tataaatttc aataattcag gtgttcgcca tgatgattga aagctgattg atacatattg 38520 cgttcctgac gcctctagaa gctctcctct gagctttgga gacccactta gggtaattat 38580 acctaaacct tgtttagacc cctcagaagc ccaatcagac accttagacg caaggcacac 38640 tactacgagt ttctttagcc ctgatttttt aaacgattct aatgccatga gtgtcttgcc 38700 tgagccaacc tcactatgat ttagattatg tgtttcccat ttgtctatga ccatttgctg 38760 ttgttccgtt ggtattaaca ttatattacc tcctccacat tagtctatca tgaaaccatg 38820 tagggttgtt gtgttgggta gtaggttata ttttgttatt attgtacaca ttcaaaaacc 38880 gtgtacactt tttgtacaaa cctgttttac gccttgtgta tcaatgtttc aaccctgttt 38940 taaccattgt agtgttgtgg gatgacctca gctcttatag aaaacaatta cattttccac 39000 ctaccataaa caccattata tcagtttttg tatatattat atattgtatt tatttttttc 39060 tttatataaa gtaataaaaa ataataaaga ataaaagaac ataagtaaac cccacgacac 39120 acgtggtatt taaccgtacc aaaaaaatgg tacaatcgtg tacatttgta ccaaaaatgt 39180 ctcaaaccct tgtcccccaa cgcttaaaaa accgtacacc accctttgtt attttattat 39240 ttttgttatt taattattat catcaaaatg taccccaaca aggtgtcccc atcaagttac 39300 cccttgcgct gacgtaaaaa gtatgctaac ataataaacg aagaacgaaa ggagaaaaca 39360 ggcatgatga ttcctacaat acacacagaa atgacaccag aagtaaaaga catttatcca 39420 ttaacctatt gtcgcgataa ggtggaccta cctatagaca ttgagtacac gaacagaggt 39480 tcgcgctttg tcgttggtga tattgattat attgcacaga caattttaaa taatactacc 39540 ctcatcttat ccacagatgg taagagtgca tgggtattga acaaagatac gaacatttgg 39600 cactatgttt ctaataatgt acgtgaattt ctactatact ctgtcattta cccacaagcg 39660 caagagttta aaagtggtga tagtgataat aaagtaggta cgttcttagg taaagttggg 39720 gacaaggtat acgaacttgt caaaggtaac cctcaattta aagagggata tttcaacgat 39780 agaacgaacg ataagtacag ataccttggt gaatgtgcgt attttcaaaa cggtgcgcta 39840 aacatgcgta cattagaact acgtccgttt gaaccatggg actatagaac gcaagacacc 39900 attttaccca ttcatgtaaa agagacacct gtgacgctac cagagattga gaaaaataga 39960 ctatggcaag cggtcaactt ctttactgac ccactaagtg aaaaagcatt atgtgagttc 40020 atagggtcat gcgtctatga gaacaaacct gaggctgttc atgctcaaat tgttgtctca 40080 cgcggtacac gcaacggagg aaatggaaag tctattctaa tgaccaaaat cataggctca 40140 ccattgtttg gaaaaatgta cacagaactc ccatctaacc gcgcatttaa cacaaaaggt 40200 gagtttaata gtgcgttact agttgacaaa cagttgattt tcattgatga attgaaccct 40260 tataatttag aaccagaggt atttaaacaa caaattacgg ctacacgcat taaggtgaat 40320 gaaaagggta aggctgaata tgacgcgcgc tttggcggac actttgcggg tgctagtaat 40380 gatgtattta aagtacgtga cgcctcagat ggttcgttaa gacgtatttt gccaattatt 40440 ttcaataagc aagtgacaaa aggtgatgac aaagtaacgt ttatgcgtca atttaaccct 40500 gatgtgtcta ctgagatgag agacgcacta aacaacgaac atgagaaagc tgagtttatt 40560 agatggtgtg tacaggagta tgctgaacta ttgaaacgca gagaggacgt taccgcagac 40620 gagtttgtgt ggacgctatc tgatgaggct aaggaaatgc gtgaggaact agtacgtagt 40680 aaaacacctg ttattgattt agcctttaat agtggactat ttgagcacac gggtaatgag 40740 ggtgaccttg ttgaattgaa actcttcacg gacggtattc ttctagcaaa cagatacaac 40800 acagatgata gaagtagaat aacgcgtaaa atggtaaaag aggacatgag ggactatatg 40860 tacaatgagg gtaaacgttc gcgtattaag gcaatatgca cgaaccctaa gcaacaccac 40920 gtagatgact tgaatactgt agcgggtcca cgtgtgtacg tgagtgggtt taagcttgca 40980 catgatgacc ttgacagtga tttagaaaag aattggtttg agacgattaa gaagcattta 41040 ggcaaacaca cgattatgga agaggttttt gacgtttact tacaacctga ggaggtattt 41100 taaaggagga ataaagatgt taggttgtga ttattgtaaa tttgaaccaa tgagggagac 41160 actattttcc tcagattact tatggagtgg gaggactgac atgactgagg tgtttataaa 41220 cgggaaaact atgacagtca caactgaggt tgacaaccaa ggttataccg ctcagtttga 41280 gattcactat tgcccaatgt gcggtggtaa gctgattgga ggaggttttt gacgtttact 41340 tacaacctga ggaggtattt taatgtttaa ggttgaacat gttagattaa cagaatataa 41400 tgacgcctat atgagtgtac tgttgtttag gcagaaagta cgtagatatt atttaactgt 41460 aaacggtaag gagtcaagag agtataaata ccacttgtgg tttttgcaaa aagtaccact 41520 attgtataaa attagtaggt atgtaaatac tcgtatagca ataaaacgca ttgaaaacat 41580 ggggggagaa cgaaatgggc tactttaaga atttgttatt agcgttgggt tatattgttg 41640 ctttgtttac cataattaag ttgggtgcag ttggttttgg ctatttaatg acattagtga 41700 gccatttgtc aggtttagta catactctag tgtgctttat tagtaacaca cttgattctg 41760 aaccgcttac aggtgtgttt ctagcctgta ttagtgcttc acctctaatt gcattgtgta 41820 tgtggcttga tgataaatag aatattctca ttaaactcta atggtttttt aattgactat 41880 tagagtttaa ttgtttatac taggttcata aggttgaggg ttaagcctac ggggtgaacg 41940 agtaccaacc aataaagaca agggatggtt aattatgatt aaggtgatga attgggagta 42000 tgaatatgga atgaaacgag tagcattcta caaagaaatt ggtcatgaga ttgagctttt 42060 agatagagaa aaatgtatac acttttatag agacggacgt tattatgcta caattgacaa 42120 aaaaggtttt agtggtggtt atcaccttaa acaaacacta aattagggga ggaatttaaa 42180 tgaacacata tacagtttat taccgtaaca ttgatgagca ctattgctgt agtattcacg 42240 ttgacgcata tactattgaa caagctatta ataaagggtt acagtacctt gaatatgaag 42300 aacatttaga ctactcagaa attgagattt gtcacgttga gaaagtgggg taaatgaaat 42360 gacaccagaa aacgttgaaa aagagtacgg tgtgtacgtt gttggaggag acattattga 42420 tatattagac catgtttttc caagctatga agaagcttta gaacatgcta agacattcca 42480 tgaatgtgat actgtaatag ttggagtagt tcaggataag gatgaagagt gatgagtttc 42540 ttaaatatat ttttaccaac aatgatgata tgtattatta ttgtagctgt agttagtgcc 42600 ttttggggac tgatagcagg actctctaaa ctacttgatt ggctcattgc taaacttgga 42660 gacagtggag aggtaattta tatgattact ttagttggtt ttatagttcc gtttattctg 42720 tctgttgtgt tttgggtaat tagtaaaatt ggaggtatga gttaatgtat attattagtt 42780 tgtttattgt agtattagtg agctacgcat taggttgggt tctatctaat ttctttggct 42840 ttgtgtttga acgcatagca gagagaaatg ttcatttagc aattttgtac ttagttgttt 42900 tagttgcttt actgattaca gtattggttt atatacttat gcgtttgttc taaggag 42957 <210> 3 <211> 13973 <212> DNA <213> Artificial Sequence <400> 3 acctccaaca gcaaccttac aaggctcgta atatgttcgg cattggagaa gattcgttaa 60 tcatgtcggc agacttctca cagcaggagc caaggctcat gactcatatg tctaagtgta 120 aggctcttat tgaagtctat caacaagctc gtgatctata ctctgaaatg gcttcggcaa 180 tctttaacaa gcctattgaa gagtgtgggg atggctccat ctggcgtaaa cgtaccaaag 240 tcgttgtact agcaattatg tatggaatgt ctgcatggtc tctggcagat gctttgggag 300 tgtctaagga cgaaggtcag aagatgattg acgacttctt caaatcttat ccggaagttg 360 accgatggat aaaggataac caagaagagg ttaagaagaa ccgctatgtg gaaacccttt 420 gggggactcg cagacggttt gtgcatgagg atttcagcat ccttaagaag gcttggaatg 480 acttaacccc agaggataag aagactcgtt caatggttaa ccgagcactc cgtcagacaa 540 ctaatttcaa agtccaagga ggagctgctt gccaaactaa acaagtaatc gttgcaatgg 600 ttccgaagtt gcaggagctg tccaaaagac gtggcaagaa gcgttgcttt aatctgcttg 660 cacaggttca cgacgagcta cttttcaaag ttcctgtaga cgttactcca gaggaagttg 720 cagatattga gaacgtcatg attaacacag ttaaattaat tgttccaagc aagactgaca 780 ttgctattgg caaagtctgg ggtaagctta ttgataagga ggagtttttc aatgaacgaa 840 gagattaagc aagagatcgc caagaacttt acgaaggtta acaattatat tatggaagca 900 actaaacgag agatggctaa gacgtgtcag gatggtggtt tcttagacca ctctctgacc 960 gctctggtag ctaagcacga tattgagcag gaagtagaga aacttaccga agcttttgaa 1020 agcatcaggg cagagcatga taagattaag aaacacgact ggatgatgca agactttcga 1080 gacggtggta agccttctgg atatgctttg aaagacttca agaagctgcc caaagaccaa 1140 ttggcaaggg tagcccaact gcaatccagt atgatttatg taatggctga ctggggctat 1200 tacaacagca gtaaggaaga gagacttaac gagattcgca aagatttgga ggacatctac 1260 aatgaagcct aattggaaag actatctgag agccgtaggt aagctggcgg ttgagctagg 1320 gcaagcgcta atcgttttcg ggatattact tctaacgatt ttcttgatta ctaagtatat 1380 gataatcttg cccctatttt gtctgcttgc agttatcgta ctattcgggg atgacttagt 1440 tagagagttt aagtctaatt cccaaatgtt tgcagaagaa cgtcacgaaa aggagaatcc 1500 atctgatgaa gcctaattta aaggactatt tgagagctgt cgggaagttt acctttatac 1560 taatagtgtc agtagctata tttatagctt ttttaggagt tatgtactta tgtatgcgat 1620 atgtaatact tgccgtgata gtttgtttgg gagtggctat agcactagtt ggcggattcg 1680 tagtatcaac agtctacgat atagctaagg gagaagctgc cgaaagagta tatgccagta 1740 ccgttgctac aaactttgga cggttaactt tcgtagaaac tatggagcat atcaatgaaa 1800 tagattctat tgtctacgag gagctgtcaa acttcactcc aaaggaacag attatagtat 1860 tagacggcct ccggaaatcc ccaatcaagg agtttaaagt tagctgttat gcagtctacc 1920 catttggcta tcttgaaaat attgaatggc gcgaggaacc tgaatacatt aagacttacg 1980 atcagattat ggaagacctc cgacttgaca ttgaaagaga tttgtgatat aatgggacag 2040 gtagaggagg tcgctttatt gaataatgta gaaacgattc acgaggctcc attaatatac 2100 aatggaatcc agtcagacaa gtatttcata agcactagag gagtcattcg aaacatcaaa 2160 acgaataagt gtttgactcc tcaagatact ggatacttac atgtacgaat ccctcacgga 2220 gatcagacga ttaatgttag gattcacaga gctgtggcag agactttctt accccgaccg 2280 gaaggctgtg atgtagtcaa tcacaaagat ggcaacaagc agaataacga cgtttccaac 2340 ttagagtggg taagccaatc agaaaacgtt ttgcacagcc ttgaacagcg ttcgggagag 2400 attattctag atgacttcat tgtaacagtc cctgtaagtg gattccgaac gtatcatatt 2460 aaagctgtgt ccaaagaggc cgccaaagaa gttatcaaaa gtggcggcac aactccacgc 2520 tcacagcatt ttgaagagct catcggaaaa gcaactatca tagaatttgg aggattttaa 2580 tacatggcta aaggtttagc agcagttaac aaggcttccg gacagacttt ggcacagaag 2640 atggcaatag actttgcaca ggagcttgat cgcttttgtg ccacaggctt taacacagac 2700 ttacagataa ctaagcaact atattctcag tatataaacg ttcttgacaa caaccccttt 2760 gaagactttc cgaaaggcgt tccattcttc cgttcaagtg gcactggaaa atgtcttcgt 2820 gagcagactc ttcgagcgat tgatgcctta gagtttacta ataatgcaga caagcgttcg 2880 gtaaatcctt ggcagaatcg ttggcagaac atcggtacag ctattggaga catggtgcag 2940 atgtatgtcc taatgatgga gaagcattat gaacgacttg ttggagagcc ttgccacttc 3000 cgtttcgaaa ggactccaga aggctacccg atgttcgaag agttttccac gacgttccaa 3060 gagttcaaga gcggtaagat aaacttcatt accggaggct ctttggacgg cattatgatt 3120 tacactgacc cagagactgg caaagagtat cgggtaggac ttgaggttaa gtctaagcaa 3180 acaacttatg cagcgactgg tcattggtct atgaaggaag ctaactccaa acacgtatgg 3240 caggttacta actatgctat gctaaaagac cttgaccagt atctcattgt ctatgtaaac 3300 gcctctcaca aaggctggaa catgactgag gaagactatg ccaagtaccc agatttccga 3360 gtatttggag tggagactcc agaagagaag aagaaagagg ttcggaatcg tttcttcaca 3420 gctgttgaaa tggctcacga aggagtcttt ccaaagcttt cgctggctga tttccaattc 3480 aatgactaca agacagcctg tgccctaagc cttacttata aggaattaga ggaacttaag 3540 ttagaagctt ctactaagtt tgaaaaagag gctatcaaag agattgagaa gattcgggga 3600 gatgtaaaat gattgaattt gtcaatgaat ttttcaatga gaacccaaat attacttggt 3660 atattatagg agtcttcgca ggttatgggc ttagaagtgt atgggaaaat gtaaggagag 3720 gtgtaaaatg attgagctga taattgaagt agcagctttt gtatttattg cttggtactc 3780 taccaatgta ggaaaactta ttgaaagaat gcgagtatac tcgatcctaa ataacactgt 3840 agataccctc gatgagattt ctgaaaagcc tgcccagtat cgcttaggct atttagcagc 3900 tttagataaa gttggacaag gagtgcataa caaatgacag atacctttta cacaactttc 3960 acgattacct atctaacccc tatctccaat gagtctggag acgacatttt ctatgaaaca 4020 tatagcttcg aagcctcaga aggttttccg gagacgaaga ttgaggagat gttaactgac 4080 ctccttataa atggagcagt aatcattgga acaaccgagg ggctactgta tttaaacaac 4140 cacaacatcg cttctatcat ggttcataag gaggaagatt gatgcgtttc atggcttttg 4200 acatctcatc tgtttcaaca ggtgtagcag tattagacca agaggctaac ggtaatctta 4260 cgttagtctt taccacaaat attattacaa actccaagga taagactggg aagcgccttc 4320 gaatattcgc cgaagagatg acagggcttc tcaatgagtt taaaccagac tttgtaatta 4380 aggagacgac aatctgtcgg atggctactc aatttattaa catgaagttc ttcgcagcct 4440 tcgaactagt cttggaatta gaagggtacc cacgctacta cgagtatggc ccgacgactg 4500 ttaagaaggt tgtcgcaggc tctgggaagt cctctaaagc agacgtagca gaggctatcc 4560 aaatctacac agacgttgat gtatcagata tgacaacaga tgaaaccgat gctattggaa 4620 ttgctcttac tcatattgga aagacttcta tgctcattcc aaaagctgag atcatggctg 4680 ctaaagagtt tgatgaacag cagcaggaag ctatggaggc tgtcggagat gatgtttaaa 4740 atccaatata cagtagcttt catcctatta gtcattgtgg agcttttgca atacttggta 4800 tacatcctag tagcacctgt tgcaacattc gtgcaagagc tctgggagag cctttcagca 4860 tttcctttta gagctatcag attcgcttgg aaaagatatt gcacagccat gaaaacagga 4920 gaacttccat cacagacaag gaggacaatt agttgattaa aatagcatta gcaggaactg 4980 cccgagcagg gaaggataca tttgctaacg tcttggaaca agagctttcc aagcagggtt 5040 atgaagttat tcgagtagct tttgcagact acttaaaaga aatctaccag caattctttg 5100 gtcatttagt caacaacgag aagcctcggg atgcttacgt aacccttgga aatgcttttc 5160 gggagattga tataaacttc tggattcgtc cagtagaggc cattagagat tatttggaga 5220 atacagaggg cttcggaaag cctgtagcaa tgattatcac tgacacacgt tactttaacg 5280 aagctctctg ggctagtcaa gaaggcttct tagtagtcaa ggtagatgct gacccactaa 5340 ttcgccaagc tcgtgcagaa gctttgggag agactttgaa attagataat gaaggggatt 5400 ctgaggttga tctcattcag ccggacttaa ctattctaaa taatggagaa gctgatttcc 5460 aagctatgcc agcagttgcc agagcagcta ttgaagagta taaagcgagg tttgggaagg 5520 ttgattagat gccattgtat aatgaatgtg gtttttacag agctattaca gaagctgaga 5580 cagcagggca gtgtgccttg catctcaaac gctttgtgac agttgtccta agacgtagta 5640 aacttccagc agaagtcaga gggctgtttg tagaagaggc ctacgagctg tttcataagc 5700 tttgggggga agaggttcca gataccttag ctcatgcctt aagcaccttc tacatgcagg 5760 acgatactac tggagggctt tctggagaca ataagtatgc taagtgtagc agctttgagt 5820 atagtttcta ctcttatcga aaagagaagc ggatagccac cgaagactat ttcctagaat 5880 cggaatttag tcctatgata gagaactcca aagtctatgg agactacatg gttgaccaag 5940 actactggat ttggcttgaa gaagttattg acagaagcaa ccttcgacct gatgaagaat 6000 acgtcttccg gaagaatgtt ttggaaggca tctccctcag aaagttggaa ggatacaacg 6060 gactttccaa aagcactctt ggcagacgtt tgaaagatgc tcgcaagaag tttaccaaag 6120 cagttacaaa gtatggtaaa gaggcaggat aacccctgtc tttttatttt gcaaaaactg 6180 ttgacaggtt tcaaaagtca tggtatgatt aattcataag ttaacagaga ggatgttgaa 6240 tatgactttt aaagtaggcg ataaagtaag atgtattcga gggagtttat ttaatgagat 6300 tcaagtagac gaagtatata ctgttagtaa agtaaccact tccgatacag gcaaggagtt 6360 gattgaacta gaagaggatt ttaatggagc ttggcttgct gaaagattcg tgattcacta 6420 tggagaagat aattctccag acagctttaa tattaatctg ggaatagttt atggaatcct 6480 ttataacagt attaaagata ctgacgaaga cttgtggatg attgcagaaa atattgcaga 6540 agctttgggg aaggaaggtt ggaaagcatg atgaagcggt atgaagtaat ctattaccta 6600 gactttgaaa gcactccacg aagttatgta gtcctagccc acagccctga agaagctgtc 6660 ggaaagactt gttggagaga acgtgggaaa gctgtccgag tagatattgt gaatgaagtt 6720 taaggaggaa ttggaatgag ttacgcagac aaccttgcga atactttctg gaagaatgtt 6780 gacactcttc ggaaagctta tggaatgacg tggaacgaca tatatgagag tggactagct 6840 tcaaaaatgt ttaaagctaa gacccctcca actatgaagc ggatggcctc tattgcagag 6900 attcttcaca cgactgtacc agagctgttg gacgacagcc ttcatgaaac tcctactgag 6960 catctttata ttgtaactat tggagaatgg gctctgacac gcttaacaaa aggccaagca 7020 acgtttacaa agaattgggc aacagagcct ctggcgtttt tcagagactt tgatgatgct 7080 tataatgcta ctaaagagtt ccctgctgcg gaggtggaag tgtggagtta agtgttttta 7140 ccaaagaaga gttggatgtt attagggctt tggtacagcg ttctatagat catgcagtag 7200 ctgcgagaat tcctttggaa ggatcggctc tgtcgccaca gcttttgtca gagctgtacg 7260 caactaatac caaaacgcta ttgacaatgt attccattag tagtaaaata gacttattga 7320 aaggggagga ataaatatgg aacagattat tttaaagagt gcaggaggat tctccacaat 7380 acaggttgac caattaacta aaggaaaatc cgtagatatt actctcagag atagtgagaa 7440 atctaaatgt ggagtctata attgggagga agtcaaacag ttcgtccgag agctatcaga 7500 actccttgga ctaactatta caaaagatat gtccaaagaa gagccgtata ttcttccgga 7560 cgagcttgtg gaaaagctta aatatgagct tagcaagaat cagccagact cagatcaatt 7620 tatctgggaa gcttgtacag aagattctga tacagttatt ggcaactggg tacaagaaac 7680 ggacaacgcc attgaacagc tatggagcat cttccaagga catccctttg aggctgagaa 7740 gttttatgtt ttaagagaca gtgatgacga ctatttgaga agctatacaa tagcatcgga 7800 tggcactgct gagggagacc ttactatgta tcctagcaat gctgttaaat tttctgctaa 7860 agaagatgca gaagctgtgc aaaggctttt gaaagactac cgcttcaata ttggacggta 7920 ttaggaggag atattatgca aagatatgta cgtttgttga ataatggagg gtacccagat 7980 attgaccagt atgtcggaaa agttttccca gttccttggg atagttacaa cctagttgag 8040 gtaaaacttc cggatgaggt gtcacgattt tttagcatat ctgatggaga ggccgagtac 8100 gtagaacatc cagaagcttc cctagacgtt gctttaagta attttatgga gcagtcggat 8160 gagcttatca gagcccttga agagacccaa gcagtgttaa aggccgctca gcaggggaca 8220 aaggagccta aagtaggaga ttttgtaaag attaagtcca aggataattt ggagatatct 8280 accaaactat atacaagtcg ttgtggctac gttggaaaga ttgtaaaggt aagtaacagc 8340 ctagcagata gtcgtaaagt atttactgta aaatttccac aagcttcttt ctcttttctg 8400 gagttcgacc tcgatcacta tgaggcaaaa ttttacgaaa gcgagtttac agttgtgcca 8460 gaaggtacgg aaggcttaca gggagtccag ccatctattg gagtatttgg aataaagtcg 8520 gatctaaaaa ctctaacaaa tattcccgaa gaatgtgtta gtatgacagg agaattttac 8580 acagaatttt tggatggaaa tgtaacaatt acagaataat ttttttgaca gttgccgaag 8640 ggtagctgtc ttttattttt gccaagaaat ttggaggcag atttttcaaa atatttttct 8700 aagttaaggg atatttttaa aattattttt ctaggaatgg agtaaatttt taaaaatttt 8760 ttcctttaat ttttcaaatt atttcaataa actcttaaaa tagcgctata acagcttttt 8820 aacgtcgtca gaggaacatt ctaagcacgt ttcagatcaa agattgggca atcatccatt 8880 aaaaatactc tgacagcctt tcaattagcc tccataataa aaacttacca cgtcttggca 8940 aagcttttgc cacagctgtc aataagactc catcaattag cacaaagcta ttcaaaaagc 9000 ttatattcat cctcaaaata acatttaact aattgagttc cccagaattt tataacagtc 9060 ccccgggatt tttaataaaa atcacttaaa acatcatgac aggcgtacga ggtttccggc 9120 agctgtccac aggctgcacc ccgggatttt taacagtttt cacttaaaac gtcatagcat 9180 atacacaaca ttatcaaggc ttttccacag cttttaggct tcttttggac gacttttgaa 9240 caagatcagg aagaagtctc gctgaaagtt ttctactata taaggcgact tttttgacag 9300 ctttcgaaaa ataaaataaa aaactttagg taaagctatt gcaatttaaa aaacgccgtg 9360 gtatattggt atcaagttaa gagaaaggaa gttgaaaaac atgaaagaaa gaatctttaa 9420 ttttgaatat ttgacacaag aggagaacga agcggtaact aatcactatc gatggtgtaa 9480 aaaagcaatg aatagaaatt tgataacgtc tagcgaagct cagtttatat ttactgaaaa 9540 aatgatcgaa gattacaggg aaaaagcctt tggaatttgt acgaacgttc caatgtttac 9600 cgaggaggta gcaaaatgac ttataacatt tatacaaacg acaattttta tgctacttgt 9660 ggaagtctga cggctgttta tagtcttgtg gctagtcttg aaaagtatat ttcaaaggat 9720 aaaataaaag tgttgacagt catttgagaa tttgataagc ttatgacgag atcaagaaag 9780 gatgtgggaa aatggttgtt tcatggttga ttctagcgcc tgtatgtgtc gtggcaagcg 9840 cacttgcttt tgttgcttgg ttagatgatt aaaaagtttt tacaaaacac tttacaaaca 9900 tatttcaaag cagcattata agactacaaa taaaattatt ggaggaatta caaaatgaac 9960 gaacaaaaac attatatcac agtcggagaa atcttagaaa ctatggaaga aagctttggg 10020 ctgtctgatt gggaaactgt caaaaaggaa cttgaaacaa tgcaaagccc tatcaatttt 10080 acaggaaaaa cagcgccaac tttgagcaaa gatcactttg ggcgtatctc tttgttaagc 10140 tttttcaatg aattggaata tgctggcgaa tggttaaccg ttgacgaatt gaaagactat 10200 ttcaacgaat tagaaaacga ttggggaggc gtttcttggt atgaatatgg tgccgacaat 10260 acttacaatt attgtggcta ccttgaaaga gatttaaact ttattatcta tgagaatgat 10320 tgcacagaag aaactctagt tttctttgct gtccatattg gcatagacgt gcgagcaggc 10380 tatacaaaat actttgcgat gaaattcgac aacctttaca aatttcaaga aaagctgtct 10440 gaacgctttg agcttgcttt cttagaatat aaggacagcg acggagacat tcaaggggta 10500 tccctatatg gttcagctac gagtgaattc attaacggtt atttcagata tgatgataaa 10560 gacttcgaag aatgtctcga catatacgac aaagaaacag ctatcgaaag cctaaccgag 10620 tttatgaaag agcaagaaat tgatttcatt gagggatctt tggaggttgt cgactaatgg 10680 ttaaaaacga atataaaagc atgtatgaag ccgaaaaaga gaagcaagca aatagcctcg 10740 tgaataagtc tttcaaacga ggcttcacaa ctattaacaa cttgaaacgt tctttagttt 10800 tagcaaagac ttcgcaagaa gcattacaag gcttgtcaac agattcaaaa agctattccg 10860 aaactatgac gatgctcgag gacaatcttt tgaaagcttc gtcacttatg ttgagtgtag 10920 agctagattt tagaaacatt catcataatt ttaagaaagg gagtgaatga cttgctacct 10980 atcttgtggg cggtttttgg tatagctgtc tggactactc ttaaaaaagc ttgccaaaaa 11040 ctttctgact acttagaaaa gcgaaaggat aaacaatttc aaaaaagact tgaaaaacaa 11100 tttaagaaag cttataataa agtcacaggc agaggcttgc tcgaaacata tcgaagaggg 11160 aagctatcca taaataacct agcgttactt ttggaggctg tcaaagaagt tgatccatta 11220 ctctatgacg acgttgtgag aaagctttct gatatgatta ggaaagaaga aataaggaaa 11280 ggacttgcaa agcctagtga gctgatagag acacctaatt tttttggaga cgattcagat 11340 gatgatttga taacacttga taaagattta tagaaaggag attgcgaaat gttagaatcg 11400 tttattttca tagctgttgc attaatcgga ggtagctttt gcacaatccg cgcgatgaaa 11460 caattagacg aaattacaaa agaagcagaa agttttaaat aaactattga aattgtaaaa 11520 aagctatgct acactataga aaagaaattg aaaggatgat aaaaatgaaa ttctcacaaa 11580 aacattacgc tatggtggag gaaagcattg gcgcttttga ccgtgcaaaa cttatacaat 11640 ataaaagtca gttgtcagaa aaggtaaaaa gaaaagaaat agtggtaaac agttttgaag 11700 ttagatttat ttttgacgtt tattatgctt gtgtaccgct accaattaga ctgcaaatca 11760 gtgaagaagg aaattacaag gataaccata ttaaaaccgc cgtaaaaacg gctttacaga 11820 aattagatat cttataactt ttcaatagaa ctataaaact tttggaggca tacaaaatga 11880 aactaaaaaa ctttacaatt acaatgttaa caattatcac agttttgaat ataacttttc 11940 tcataggtaa aaaagcttat gagaaaggct atcaagaagc ttcggaagct aacaaagtca 12000 acaatgagct tctcgcagaa gcagaagata ctatcgaaag caaccgcaac acgatcgcag 12060 atctcaataa aaagctagac tcttatgcaa ctatcaaagc agactttgtc attgttgaaa 12120 gcgacacgaa aaagttgtac atttatccga tcgacaatga taagaaaact attcagactt 12180 tcaaagttga cgagggaata ggcatagaag ctgtcaacaa ataatcgaac agatttagaa 12240 aggctacttc ataattggag tagcttttta attattaaga aaaggttaag aatctatctg 12300 ttatctatca ttttgaaagc tatcagaaaa gctgataaat aagcttgtag atatcttgtc 12360 tatacaagtt gtacgttatg cttcagagag cgtgggactt aactttttta aaagggtatc 12420 tgttatgtaa gtaacagatt ataataagct attacagaag ctactccatt atctaataag 12480 aagcatactt ctagaagcct ttgcaaaagc ttcccaaggc tttccaaagc ttaggcaagt 12540 aactatcaat agcttatcct aaagctatca gaaagcctgt caagaagctt atcctaacaa 12600 ctaattaaat agataaaaga gaagttgcac cattgattgg agtagcttct ttttatatcc 12660 tcttaaatag ctcacgagaa gctctctcag acgtttcatt atagaatggt aacctactat 12720 tagcctatca tttggggagc gtagatgaga atatacaagg catatttgag aagcctattc 12780 tagcaactat tataggcgtt actcaagaag ctattctgga acgtggttca caactatccg 12840 agtagctgtt acgctaactg tttgtgagtc tttctgatcg cctgataata gcttataatg 12900 gagcgtgttg catggcgttc gataggctgt caagcacctt gccacagctg tcagactaca 12960 gtcaatcagt caaacataaa cgtaaaacct atatagagac gtcgaccaac tgccgaccag 13020 ctgttgatag tcttatggag tggcttctgt aggctatcga acggctgttc gcatatctat 13080 tgatctagtt tacataatgt gtattataca aagttgacaa gacacattga ctcaactgtt 13140 cgacagtctc gacacacgtt gaccgacgac cgaccgacga gacacacgac agactcacga 13200 acagctgacg taataggcta tctgacaggc ttcccaaggc gtgccagcta cgttgacccc 13260 agcaagggag ggggtcttgc cacagctgac cgaaggcgcg cgcactgtta gcctctgaca 13320 acttttgcaa gtttccgtgt gaggctgtcc gatttatttt ttctggagtt tcctaatagg 13380 ctgtccgaca gctgccgaca gactccgaaa acggctggcc aattttattt tttgcagttt 13440 tcctaataag gcttccgaca gctgttacaa tcacacgcac gataagctgt ttggttagtt 13500 tatccataac tccatacaga acaaaataag ccgccctccg acaagctgtc aaaaggtggc 13560 tcatataagt attatggagg cttaggcaaa gctccagtag aggcctttgt gagtcttttg 13620 gcgaccgtta cagcaatctc ttatacgtcg agggataaac cctttattac cagcctctgt 13680 gacgcttttg aaggtgtgaa ctatgtttcc ttctgaatcc tttgcaataa ctggtttgga 13740 ctgctttttt gccctccgtt gcctagccgt tccgtgtaag ttattatacc gataggtaca 13800 ccattcgagg ttgatgacac agttgttaag cttatcttcg tctatgtgat tgactattgg 13860 aaagttgtta gggtttgggc aaaaagtctc tgcaataagc ctgtgcattt tatgcggcat 13920 cctattcata tatacaacct tatatcctcc aatgttcacg taacctaagc gct 13973 <210> 4 <211> 10503 <212> DNA <213> Artificial Sequence <400> 4 ttgaaaggct tcgaaaacgg tcagcaagaa actggcacaa tcgacatttc tgacgaggat 60 attccattct aagaggggcg caagcctctc ctagtcttat taggaggaac tatggatact 120 attaaaatga ctacagaaga gcaactagca ttagttgatt tcatggctat ctacaatcta 180 ctagggcaac tagcacaggg agacttcgtt aactatgacg acactgcgac ggctatccga 240 atccacgaca acatgcgtgt gattgagtct gtattggaac atgccgaaga ctcagtagag 300 ttcaaagatg tccgcaagca tttgctaaac ctttcagacg tcttggtaac acgctggaaa 360 cacttcttac ccgaagctga cctagcagct atcgaagagt ctaccgataa gttccgtgca 420 aaagctattg agcgacttgt ggagaacgga ctttcagaag aagaagctca attagctgta 480 ggtaaaattg gtctgaacgg aggaaactag atggcagttg ttggagtgat cttactaatc 540 atcttagtag cctttctggc agctttggca ggggctatgt gggtgctatg ggcaatcgtt 600 catttggctt ccgttactat tgacgaagct gacgaggagc ctttcaaaaa ggtgctagat 660 ttattagaag atgctattga aaaatattat cgagcaaaat ttggcaacga ccttgactca 720 gtagaattag tcatggacgt aacctacaat catggagagg atgaagacta tgagcaagtt 780 tagttatata gccggctacc tccatggcaa caatgtttac cagacgttgt ccgagtttta 840 cttagatgac gtgcacatag aatcgacaaa gtatattgga ggcctcccta caaaagagtt 900 gtttaccgca gctcttacgg aggctgcccg agaagctgct tacgatgttg tggcagaggc 960 tgctgacaac ttccacaaag acattgtagt gtatgcgcac atagtatatc aagggctctg 1020 cgtagagttc cataaagagt ataacttaca cgacttcatt gacttcgaag acatgagcga 1080 aacagttgag aacgaccttg ctaactgggc tgtgatgaag tttggcacag ttattgcaca 1140 gcttccggag atgattatca atggactata gcagactata cgtgggcgac aaagttttgt 1200 accaaggaac tacctgtgct aacacagtga ctaagggaaa gacttacgaa gtagtccgct 1260 tgacaactaa gccaaagcat ggtatcatta tagatgattc aggaaacgat aagctcattc 1320 agatgggcta tctgtttgca aagattggag gaagctaatg aagtacgata ctaacaaaga 1380 gatcaatgaa acagccgatg ctgctaaacc tattctagaa gagttagaaa ttgatcttaa 1440 agaggacgag tacgttatcg tacagcctta tggagatggc aatgctatta tcattcgagt 1500 ggttgaggaa gaggatggta gaactattaa agtagaagta tctgactcag ttgttgtgct 1560 acctgctaaa gatggtttac tggatgtatt cgcctaagat tggatgaaga tgaatgaagc 1620 gatcattaat catttgggta gaagacgttg gcacattaaa gttcgagaat gtccaagact 1680 tttccgacta caaagaagta atcaatttca cttatgatgg agtatctact aatgagacta 1740 gggcagcaac cttcaacaag tctaaattag ttggatacgc ctttacaaag gagggaaata 1800 aacatgttag aaactgttga aaaacgtatc gctgagcttc ttgcggagac cggcaaagag 1860 gttacagact tgcaagtaac tgttgaacat ggagttgaga agcctgactt caaaggcgac 1920 atgtacgtag cccaagcaaa gcttgatggg gaatctactc cattagctaa gtggacagtt 1980 ggcgacaact tcaaagacga ccccgatatg gtagagcctt tggcacgaaa cctagttgac 2040 cgtatgttgg aagactatgg ggtggaagaa gagtaactag caatgagccc actggaagct 2100 cctgacgagg ttcttcaaaa agagcaagcc caacagctca cagaggttga acggctgctc 2160 cagtcatctt tttgggcttt gggatggacg agtctacgag atggctcaag tgcacgaacc 2220 atatagtagc acgtaagtgg aagctgttgg tagggcggat tgcctcagtg tgtttggaag 2280 gctgaggaac aagcttctgc aagggtttat gggagatacg cttcggagaa atcttccaga 2340 atattggctt agacttagag agtagctttc cgaagagtga atgagtcgaa aaagaacgga 2400 ctaggaagcc ctgccgaagt ccttcgaaac ctgtcactag ccgtgaatag tttgttgact 2460 gtcttgtcac agtccgtgtt tctggaggct gaggatactc ccctatccaa ggcctttgga 2520 ctcacagaaa tacctttacc atttcattta accaactcct tacgaaaaca aatccaagaa 2580 gagaaggaca gtcttgccag aggctgtctt tttgtttata taaaagcttg acaagaggct 2640 gactaagtgg tatgataggt ttatcaaagt tatggaggtt agctatgtac aaagtatact 2700 atatcacttg gaaaggtgcc catgacgttt tctggctctg tgcaaacagc caagaagaag 2760 ctgcttggat agcttctacg atccaaggtg tcggagagat tgaaaaaatt attaaggagg 2820 agaattgata tgaaactttt ggaaaacttg aaacatgaat gcgtagaggc tcaggcagta 2880 ctccctaatt actatgaaga tgagccaatg cttacttggg aatccgttga agaagctaac 2940 cggaagattg acttcacttt aggagaagct gtcagaaact gggcaaatac ttttgctgac 3000 caatttccag agcagtgggc agagcatgac gagtatgctt atcgaatgct gtttggagag 3060 tctctgatgg cattgcctta cgaactagat ggctgcgatt gtgatttcga ggaggaagaa 3120 taatgaaggt caaagagctt gcagaagtta tctacccaaa tacttcactg tacattgacg 3180 gtgtttctaa tgcagctggg aataccttta tgaaactata ctccatcgag tatctcgttg 3240 agcattatgg agaacgtctc gttgaagaga ttgaaacaga acacgactat gatgccagct 3300 ttttatatat tacattgaag gaggaagaat agatgttaga tatgcgtgta gaagattatc 3360 gaattagctc agacggcaac caagtaatcg tggaaagggc tcgttggaca gactctggag 3420 agatttccat gctaactgat aagaagactg gcgaaaaatt tgagtcacgg tctcttgttg 3480 gctattacca aaacttgtcg aaggctctgg taggtatcca aagagactgg gtactatcta 3540 ataacggaca ttccatcaaa actatccaag actataagaa ggctatcgac gacattacaa 3600 aagctttcga agagtcagta aacttagggg aggaatttta atggatgcca aattaagaga 3660 gttccatgca gcctattgtg cagcttacga taagctttcc acagctgatg aaaagctttc 3720 agatgctaga aggtactcag agctttatgt aagcagtgta ggtaactttc cagaagcctc 3780 actaaccctg tcaggagatt actctgatga tagagtatta aaaatacctc gcaacttact 3840 tgcagaaact gttgcagagt atatctcgct tttagcagat gaagtagacg aagccgaagg 3900 agagttacag gatttaatta acagcatgaa ggaggacgaa agatgagctt tgaagtaaaa 3960 gcttggttaa atcttaatgg aggggatgac atagaaatgt ctgtgcaggt tcccaacaat 4020 gctactgacg agcagattga cgaggctgtc aaaaatgaaa tcattgcaca tctcgactgg 4080 ggttgggaag acccttatga agagccttat gaggacacct atccatgtgg ctgttgcatg 4140 tgctgtggtt gtagttgcga ttttgagtac gaggacatgt ggatagacga agactgggag 4200 gacgagtaaa tgctatttaa agctaaacca aaagcttctg cactggaatc gacagcctat 4260 tcctaccatt atggagagtg gaatttccct atagatgctg acggatatat tcatggatgg 4320 tatgttgatg ggtatattgt aggagctatc gaagagtcta ccgaagagta tattgcgcca 4380 gaattctggt gccctattga gaaagacact ttggaaattg atttagaggc tatctcaaaa 4440 attgctagag gagaggttga agggactgag cacatagata agcttttagc cctcgatgaa 4500 cttattccac atgttcttta tttagacaga tacaaggagg acgaataaat gtggacatgg 4560 ttttggaaga actctaatac agagacttac agtaaatacg gactccatgg ttcattcatt 4620 ggagaccctc ctcgagtagc tgtgggagat gtttatacaa gagtagatgg atatgctcca 4680 ttaaattata ttgtcacagc tattgacaaa gagcgacaat tagttaaaat ggaattaaac 4740 gcaagataat ggaggaaatc tttaatggaa gaattatgga agccagtggt tggctatgag 4800 ggtaagtatg aagttagcag ctttggtaga gtcatgagct tgaattacag caagcaggga 4860 gagccagcta tccgaaaact atctttagat aaagacggtt atctaaacgt taccctctat 4920 tctcttggaa aacctaagac gcttaaagtc catagattgg tggcacaggc attccttgaa 4980 aacaatagta atcttcctga aataaaccac attgatgaaa ataagtcaaa caaccatgta 5040 gagaatcttg agtggtgctc taggtcttac aatatcagct atggtcaagg tagcatacag 5100 agggcactgt ctaaatgtcg tcaggtagag gctgttgaca gctcagggat ccgtcgccat 5160 ttatttaaaa gtacccaaga ggcaggaaga aacggattta cacaatcgtc agtggctgct 5220 tgttgtagac atgagcagtc tcatcacaaa ggttttattt ggaggtatat tgatgacact 5280 agataagata caccttacca aggaaattct tgtactcatt gacatacctg agtacctaca 5340 gagatatgat tgctgggaga acgctaaatt cacagacgag cgactaatct gctccagtcc 5400 ttttcgaccg gactcttcgc caagcttctt tgtaaacttt aacaatgagt ttgcagggac 5460 ttggggagac tctggtagtg gagattccgg aaactttata aagcttgtat cactactcga 5520 cgaaacaggc tatgaagaag ctttggacaa gcttcgggac gagtttatgt taggggctta 5580 tgacactcca cagataagcg ttggggtaac tgcttcccag agtcgtgata gcttccggaa 5640 agtcccttgg aataagtctt tgtatctact ttcccgaggt atttcagaag ctactcaaga 5700 agcctatgag acatctgagg gagacgactt tataaggctt ccgtatgttg atggagtagg 5760 agaatggaga gctattaagt atcgtaaaac attctctaaa gacttcttct atgaagctgg 5820 taacaatcat atcaaagatt tggtattcgg ccatcgagtt atttacaaag agaatccaac 5880 aactcttgca atttgcgaag ctgagatcga tgctatgaca gcttatgaaa tgggatatgt 5940 cggaataagt cttggttcag ctaacttgag cgactctcag ataaagctta ttcataagtt 6000 cggagtagat aatattctga tagctacgga caatgactcc aaaggtaaca tggctgctga 6060 ggatattcgc aaggcctttg caaagactca taacgtttat agggcaaatc ttccgaatgg 6120 agaagacttg aacggatact ggcagaagaa ccactccaaa ttaaaatgga taaagctgtc 6180 agaaagcaac ttactaaact ttcgaaaggt gtggttttga tgatttttaa aacgattact 6240 tccacagata caatggggag cgagattgaa gagaatatcc aactaactta ctcgccttct 6300 aaaaacagaa tccagttgga gcttagttat gaagaccttg aggaggatgc ttcatactac 6360 atggaagatt atattaaact aactaaggaa gatgctttga aacttattga aagcttgcaa 6420 gagttagtta aagagatgga ggacgaataa tgttaaaacg aatatatagt aggcttgacc 6480 cagatgagtt tatagaatta gaaaccatat caggaaccta ccttactgtt gaatcaatgt 6540 atcatccaaa ccacgactac tctggaagga caggagaggc gcatactttg aacaactttg 6600 tatcactaga caaacatgag gtcagaacac tcattggaag tctgcaagaa atgcttaaag 6660 agatggagga atcagagtgg atataaaagc aactgtatat ttaaaatcag gtggagatac 6720 tagcatgata atttatgata ctacattaga agagcaggat aagcaatatt caaaattctt 6780 tgagaagggt attgaaaata atattatatg ccaccaaacc aattccgagg ttatattcat 6840 tccagtttct aatattgcat gtctaagctt aaaagagctg cctaaataaa ctttctgaga 6900 ggccttgaca aggcttcttt tttatgctat tcttaatgag tagaaaagcc actaaaggag 6960 ttgctaaatt gaagaaatca accttactta aaaaactgat attagagact ggcaaaactg 7020 aggaacaagt taagcaaacg ctatctcaca tccacctcca gttattcggg ctgtctggag 7080 agagtggcaa gttcggctct gctaagatac ctctggaata caatgactta ttcttattca 7140 atagccctgc caaggatgct cagccagcta cttacgagct tttggaaagc tatgttaaga 7200 gtttccggag atactttgcc aatccggaag aggaatctat caagaatctt tacttgtgga 7260 gtccagagaa aggcaacgga aagacttcca cagctgcggc actgcttaac gaatatatgt 7320 tcacagcatg gaaagcttcg gtaaagctta aggcaactat tccacagcct cctgcatact 7380 ttctagatgt taacagccta cagactttgt ataaccgttt cactcgtcaa ggagtttcct 7440 atgacgttac agaagaagcc tccagaaaat actatgctga gatggatgtt gcaaaggctg 7500 ctccaatgct tgtggcagat gacataggag ttcgatcagc tacagaggcg tttcgggcag 7560 acttgcatga aattatcaat tacagaatgg ttaaaggact tccgacaatc tacacaagca 7620 accttccact agttgatatg gagcaagtct ttgatgaacg tctttatgat aggatgcgtg 7680 ataagactgt tatgattagg tttgagggag actctaaacg tggggtcaag aataagtcca 7740 ctaaggaggc taaataatgg ctagaaacgt tacaggagag ttgctacttt caaaggttat 7800 taacgagaat gatgttgcag cactcaaccg ccacggaata tccagagaga tgtttccggt 7860 agcttccgaa agagatgctt acgattttat tatacactat tcaagaacta acgagggtaa 7920 cgcacctagc tttgcaacag ttattgacaa tgttccggaa ttcgactaca ttccaaatac 7980 ggaagactct tttacatatc tgtcgaaaga gcttaagaag aagaagttcc aagtcgagca 8040 agctaacttc attaataata agctatcaga attatggaat gaagctgata aagctaacga 8100 tccggaagga tttgccaacg acattattaa agctttcgag gagatgaaac actccaacag 8160 aatatctgga aaagctggcc atcttttaga acacgctggg gactggtatt tggaagagtt 8220 ctacaagcgt aaggaaggca agtctatccg cttttggaag agtcattttg aaggacttaa 8280 cgacatcatc ggaggaggtt accaagagtc taatatgatt acttggtatg gccgttctgg 8340 tagaggtaag tccacgatca cacttatgga aggacttgag gcagcttatc aaggagctaa 8400 tgtattattc tgggtgcttg agatgcctaa gtatgagttc gccagtcgtg ccctaagctt 8460 tatctcagct aaggaaaagc ttaagaattc agttattgat ggagttgact acttggcagg 8520 gtttagcgta tacgacttga caaaagcttc tttcaaaact gttgacgagg aacagtcgtt 8580 cgtagacttt gtaatgaagt tgaacacagt cttagaaggc tcaattacaa ttcgtgctat 8640 agatgatgaa gactttattg atcgctctgt gagagctttg gaaagagaca ttgtagagag 8700 tgaagcagat gttgtgatcg ttgacccagc ttactacatg gactacgaga agaatacttc 8760 taaaactaac ggaggagatg ccgcagctac ttccaaagct cttcgaaagc ttgccggacg 8820 tacaaaagtt gttatgcacg ttattacaca ggctgaggaa gatgactccg agaagcgtgg 8880 cgatgagcgt gagctaaaca ttccaaagcg tagccaagtt aagaagacaa aagccttgct 8940 ggaagatgca gctattgtac tagctttcga cagttgtgac ggaatctttg gactagaagt 9000 ttccaaagga cgttccggag gagaaggaga aggcatagaa ggaatcttct taccttccat 9060 tggatatatt gaagagaaca gtcaacaggt cgtcgaagag ttgtttgcag atgatataga 9120 attttaagga ggtagaaaga tggcagctat tatacagttt tcagacggaa ccttccacgg 9180 cggagggaca gttaacatta agccagtaaa agaggcggaa cgagccaagt catatgttag 9240 tgttaaaaag gctaaggcag ctctccgaag tcttaatggt acctataagg atagatggaa 9300 tgagcagatc gaaggagcta ttgtgtggga agttgagtat atctttgtaa aggggtacaa 9360 atatgaaagc agttgagaat ctactttttg taacaacctt tgccaacaat tggtcagtca 9420 gtgtagccag agttgatgat ggagagtacc gatggagcgt acgttacacc aacccaaaag 9480 gttactcagt ttacaacatg tatgaaacgg attcggaagt ctttttagag ctggctaaag 9540 tacagaaata tgaggaggac gaataatggt agaatttatg ttagagctat gggcttggag 9600 caagtttttt gaatgggctt ttggagcagt cgtggtagta gttttcgtag tagctttgtt 9660 agtatattgg ggaatccatt cgtacaagct tcgaaaaata aataagaaat agtattgaca 9720 attcctctga ttgatgttat gattaattca taagttgatt ggaggaattt taaatgacat 9780 atgcacaacg tatgaaaaca ttctacaagg ctcatgaaaa cgacttggcc ttgattggta 9840 acaaaataga agcacataac ttccaagtag tctatgacaa agactccgga gagtttctga 9900 aagtccctac gaaagtctct ttcgcagctt gcaaaaataa ggcatgcaaa ctgtgtaagg 9960 agattgctga gctaggtaag atagctgatg aagtagctca tgccagaatc attagcagag 10020 gctgggagaa ggcttctata tactccattg cacgtcttgc ggatactgga atgaacttaa 10080 atgacattgc agatgcttta gaaacgactc cagaagttat ccgaggactg attaaggacg 10140 acattgaatc tgagggatgg tctatggagg atgttgtacg actattcaga acgactttcc 10200 aagtctctac aacagttatg tatgagctaa ttccatatac tgcggaagac gttcggaaag 10260 ctattttaat aaacggtaaa aagcttacta cactgactgg taagccacta catttagagg 10320 aggaagaagg atgaataaat accatatata ctaccgttta attgagtcac agttcactga 10380 ttactgcgta gtagtgacta attctattca gtctgcaatt gacaatgctc tggagaacat 10440 accaatttat gaccacgtta aattatccga aattgatatt tgtcacgttg agaaagtgga 10500 gga 10503 <210> 5 <211> 8553 <212> DNA <213> Artificial Sequence <400> 5 cttcttgcac ggaataatgg tctactcata agaatcctcc tagatgttaa ttttcataag 60 cttatccaac atcctgtccg tatactcttc caaagctggt ataaagtttg ggtagttacg 120 ttcgacgatt ggagcatagc ctctgtgtcc tttagggttt ccagagacgt ttgatttaac 180 tattccatat gagatacgcc ctcctctgga gacttttgtc tcagcctcta aattgctaat 240 caaagtagac gtatcaatgt tgtcatgagc gtggatgtta tacttaacag cttgtctcat 300 ctggtgggta tttgtgtcca tagctctctc agtctcatcc aaccagtcgt cgataagttt 360 gtcgaagtta atcttcttga tgatgtctat tcgtaccctt cccatatagt accatcctcc 420 ttagtacgtc tatagtctcg gtactcaact aggtaagaga ctgtttggtt aactccagtg 480 gtattatttt catagatgtt atacaccttg ccagtggagt ggaatcttac cgcatcaatt 540 actaagtctt tcaactcgta tatcttatgc tgtacccgat accttggaag ccattggaca 600 tcttggttca taagtagctt ctggtctgtg gccatgcttc cgacagcggc aggaatccct 660 ctagcaacta tggtaggcgt tgggataatc gttccgaagt cgtcgtcggt atcagtaaag 720 tcgttatact ggataaggtc aatgatttca ttaatcttca tatcacatca tcctaaactt 780 tctacccttg tatgtgccgt tgttatcagc ccatgcgtgg agagttgaca tccagtttaa 840 atagatgtcg tctttgtagt cgtaacgagt gatgtcagta gactctgttt taagtccttc 900 agagttcaga ctggacaacc ttgcggcagt tagttcatcg gctatgtaat caagctccat 960 tgggaatttg gttacctcga cgttgataac ttggcagata tgctgtctgg cacgtttctt 1020 aaggactttc agcaagttgt ctcgaataga cgagttgaag tagcctagca taagcttgat 1080 ttcggatata tcaatagctt ctacatctgg aggaaggtcg gcttgttgat aggcgttgaa 1140 agcatctaat aaagcttttt gctcttccat aatgacctcc tataaaaaag aggctaggga 1200 ttctttccct aaccccttgt tagtcttact ccgctgctgg agatactgtt acagcaattt 1260 tagcagttac tccagaaccg tctttagcag ttgcggtaat gtcagttgta ccctcagcta 1320 ctggatgaac ttttccccca acatatgttg cagctgctgg gttagttgat tcaatagtca 1380 actctttatt cgtagcatta gctggtgcaa cagcgaatga aactgctcgg tcagcatctc 1440 ctactttaat tgacatagtt tgctgagaag gtgtgatacc agttactttc tgatctgctg 1500 tagtgacttt aaaagtagcc ttcgcagact ctgtaccgtt atctactcta gatactccaa 1560 aagtatattc ggtagctggg tctaagccgt ctactgtgta agtcttttcc gcaacgtcag 1620 aagcaatctt ctctgaacct ttgtaaatgt tgtaagtaat tgccacggtt agtttccccc 1680 ttccctattc ccaagacaac gtcacactag gggcagtgac gtcgcttgag ctaagatttt 1740 ggggcgcatt agggtgtaac agttcctttg atgtaaacta ctttcgtagt atcttgaacg 1800 tatgttacgt agtgttggtc agcggagata gtcgtttgac gtttgaaacc ttcacggatt 1860 gtttctacgt tgtagccacg tttcataata agtttcaatg caccacgttt gataacgaat 1920 gcttcgtcgt tagcaagctt gttagagatt acgatacgca taccgaacaa ctctcccaat 1980 tctcctgtga tgatcttacg tccttggtca atgtgaacga agtctccaga tttcaagatg 2040 ttagcacgac tcttaggaga gatgaacaag aatgtttcat cgtcgaactc ttctccaaaa 2100 gctacttgag catccaatac ccatccgtaa ccagctgggt caatcttaac atcagtcgat 2160 ggagtcaaag ctttaatctt atccacaaag tcgttgtcga ttttgcttgc gattgctaaa 2220 gctaactgac gtacagtttc attgacaggt tgtgtataag ctgatagaac agcctcgtcc 2280 gtcaatgtaa cacctttaac aactttttta acagttgctg tagaagatgt tgcagtcaat 2340 ttaactgggt cgaacgctac accttccgct acgtcgtcag cttctccgat gaagttccat 2400 tgaggtactg tcaaagtatc gcctggctga ttgactaaag tattgtcaat atctgccaaa 2460 ggtgctaaga taaggttgtc gatcattttc ttctctagga agtctccaat gacctcgggg 2520 ttgattaaat ctgcaatttt agttacttct gctaccatgt gtattctcct tttcgtatgg 2580 acttatctaa ttaagagtta cgtcgcaaag cttcgtactt agctgggttg cttgctttaa 2640 gctgcatagc ttcttgagga gataagtcga ataatgattt agcttctcgc tgccctccaa 2700 cccctacaat atcttggttg ctaggtgctg tctgagctgc aaggcctttt actttttcct 2760 ccacacgttg tgacaagagg ttattgattt ctacgtctaa agagttgacg ttgtgtttcg 2820 tagcttctgg agaatctcca atcacgtagt ctgcaaagct tgccggaagt cctgtagctg 2880 ctaatgcggc tgaagccaca ctttgcattg ctaagcggtc tttctctgct tggatttctt 2940 tgagctgtga ctgcatctgc cgaagttgaa tctgctcttg tgtttctgga gggtttaatt 3000 cttgtaaccg ttcttgaacg atcccttcca agtgcttact cttccaagac tcaatagctt 3060 tggatgcaaa ctggtctaac cgaggactaa tgatagattt gcctgcttcc gtttctaaga 3120 aacttcctac tgtatctttg tttaagaatt gactttctac gcttttacgc agttctggat 3180 tggattcgat agctcctaaa acagtttcaa cagataaccc ttctgtgcct tctgctgtcc 3240 cattgccttg ttctttcata atttcgtctg ccatgattgt atttctcctt ccgccctcgt 3300 aggtacaacg ccctaccgtg ctttagatat agtattttgt aaagtccttg gcttaggtgt 3360 cctttaacat ttaacctacg agattacagg gacaatgatg cagacacaat gaggatgcac 3420 agggagaaga ggtaatgttt ctagggtata gagaccctcg tttctgatac ctccgtgagc 3480 taagcttttg caatgctcac aaactccact aacggttaac tctggtctat tgctccattt 3540 ccataatgtt atctcgtact gtttggaagc ttccacaaca gcaagattta taattactga 3600 ggcttgagcc tctacatgtc gtctgaggaa gtagagaagg ttgtctctaa gctgttctaa 3660 gtgagcgagc ttgccttgac tctctcctaa aacgactgtt cctgtagcta cgccctccaa 3720 ttcatagagt atcggaagta agatgctaaa gaagtagtcg taagcttctt cgataagctc 3780 ttgaattgcg ttcgttatat ctacagaggc tatcccctct cctaatgagg ggtgtcccac 3840 gaccttttca gcaacctccg tgaaagcttt tgtaagctct tctttgaagg ctgtaccata 3900 gactgaggtg tagtattcta gtaagctctt ggagtcttgg ataagcatat agtctggaga 3960 ctctttcata gcttctatga taatcttatc aacaacagcc tcaagttggg gagagtacct 4020 cccgataata tctgcaaagt ctttctgagt atctatcatg acatctgtca gaaaggcttc 4080 cagaagttct tggcgtttct tcttccccat ctttctagcc atctataatt cctcctagtc 4140 tcttggtttc ttgttacgag atttctcctg ctctttagca gctactgcat cgtctgtggt 4200 aatcgtattg gcatcagttc gattgtctag cttcttgacg ttttgatctg atgtagcgac 4260 ttgtcctaag ttagtctgtt taagcattga catctctgct tgaatcttca tacgttcctt 4320 acgctgttcg ttagctttct taacctcaga ctctgggtca gtaatgaatg ggaactgtgc 4380 gataatcgtt tcgtctggta gaatgtcacg aagcttaaca gccatatctg ccaactctga 4440 gaatgattgt ggaaggttac gtacaaagac tggttccact ttctctggtt taagatcttt 4500 agcacctttc aaattagtca agtagtggca gatgatttca taacgttggc ggaatacttt 4560 gcgaagctta gactcacgaa ctgctgactt attctccaat ggttgtgtag cagctttcat 4620 agctgttcca gtagctgcat tgaagtcttt agaagtcaag tctggagttt gagaaagact 4680 aaagatgtta cgctcagctc tgtctttgat gttctcaata tgagtatcat taatgttctt 4740 gactagccac tcagcctttc cgccttcttc ggtaaccatg acacggttgt ttttcatctt 4800 atccaactca gagttaccgt tttcgtcttc tccaatgtca aatccagcta accataggta 4860 ggcatcgttc aaatagttaa tgtcatttac agagtctgac acagctaagt tgtaagcatc 4920 aattaatgga atctgagctt caaagtctcc cagacgttct tcattagcaa tgacctcaaa 4980 tacattaaac tttcctagta gattgggaaa agtttctggg ataggcttgt ttttagttcc 5040 atcttccaaa gtctctgttt cgaatttaat aatcttatct ttagtataga cttcataggt 5100 tcgatacaca gctctagtag cactttggta caccgtgtta taatagattg ctgccaaagg 5160 ctcattatcc aagtccatcg aatagcatag taccatgttc attggagaaa ttgctttgat 5220 acgatagtct ccgttgcggt ctaggtaatg gatttcaaac gcatggccaa agattccgga 5280 aagcttaacc aactcattgt caacgtcatg gaaatcattc ttattaagaa ttggaagcat 5340 tgcatcaata gttgtctcgt cgccttttaa agtaattggt tccccagcta agtaagaggc 5400 tgctgtatct actaacagtt tagggaagtt gtgaacgact ttattattag gctttgtctt 5460 atcgtcaaac gttctgttta gaatagcgtg gtgcatgcct ttgtaatagt catacaaaag 5520 ctggtagcta cctactctcc catagtggag ttcagcagca ttgattaagt cgtctgttgt 5580 aaagtctctg gttatatagt gcttacggtt atcagcgact gtataaatgt ctccagcaga 5640 cagttggtta tttggaatag ccatgtgata gtcctcctta attgtcttca aaggtacagc 5700 cccagacttt tgtataactg tcctacagtc cgaaagcagc cttactgata gaccttactt 5760 tgtttcttgg aatcatgtct gatacagcat accgaagagc atccatacag tggtcaaagc 5820 cattggcacg aggtttgtta aggtactcgt ccttaagatg tttgttaggt tgccactcat 5880 aattctccag ctctgagata gtccttacac agcgtggatc aacaacgatt gtgtagcctt 5940 gcagatattg gataccatgc aagatgctgt ccttcccttt tcgtgaaggt ttaatacgtc 6000 gtgccccaag cctccgaagc tcttcaatag actttggctc agcgctatct gcaaagattt 6060 cattgtggac tatcttacgc ttcttaatct cttcgaagat gtccttgttc aagaggcctg 6120 tttgatacat ttcatcatag atgtaaagac atctagaaga ttcatcgatc ataatggaaa 6180 gtagtacggt agggtcattg gtaaacccga agtcgagtcc ccatttaggt ttccagcggt 6240 ctctcaaaag cttacgcaag tctagccgct gtcttgtcca gtttgtataa atgcgtttac 6300 caaggctggc aaactttcca agagcgtaga tttcgtagta tactgggtta gtattcttca 6360 tgtcctctaa ctgcttgatg tatgatctag gaaggaatcg attgtctttg taagttgtac 6420 taataacttt gcaattctct ggacgtttct tagctgggtt atgaaacatg tggtagaccc 6480 agttatcttt tgaagcaggg ttatacataa taaatacttg gttgtttccg gcagccttgt 6540 tacgcagccg tagttgaagc tgtgagtagt cgtccaaagt gaactcagta gcttcctcca 6600 taactatgtc agagataccg gaaatagatt tgatacgctc tgggtcttcc atccctttaa 6660 atatgtactc tgttccatta ggtagtttaa tagtcatgta tgaagccttt acatcacata 6720 tgtcgtagat gccaaactcc tgtagacatg tcttgtattc ttggaagatg gagtcccgaa 6780 tcgtattatc aactttacgt gtgactagaa acttacgctt acttgctaag ccttttagaa 6840 tcgtattctg aaccacaaac ttagacttac cagaacctgc tcctccgtag aaaaccattg 6900 tacgatactt accattaggc ttattatata agtatggaag gtaagcctcg ttaaagattc 6960 ttggagggac tgtaagtttt aatggaattg ttttattatc gtttgccata gtgtcctcct 7020 aaagtagata aaagccccac agaggttttc cgtagggctt cttgattatt tgttgatagc 7080 attgttaaca gacttgccag tctcgtagaa gcctacagac gaaagccctg caataagtcc 7140 tgcaactgct ccgataactg gttcgacatc aaatacaatc atacctccgg ctactccaac 7200 gataacgcct aagacgatag ctgccaaagg aatgtaccga gctggaatgt actcttgaga 7260 tttaatcata ttcattaagc ctgtcataac tgccccgatg ccgactgcaa cggtcatgat 7320 gatttcagtg ttgttcaaat ttaccacctc ctttaaaggt ttctaactct tctttcagag 7380 aggcgttttc ttcctcaagt tcgtcaacac gttcctcaag ctgagaaatc tgtagcaagt 7440 agccgtcttc cttctcttgc atggaacgct tcaagtcagc catctcaaat tttaactggc 7500 taaacttttc ctctaagtcg aaaacagttt gtcgaacaga gttgtactca gcttttagct 7560 cgttgtgatc ggctgcctta gtctcgtaca tctctttcca gctagtgtaa atctcgtcac 7620 gattctctat ctcagtcttt ctgactagcc ctttgaagtc taagtttttg cctacccaag 7680 cagttacaaa ggctaataca ccagtgatta gtacatccca gtgctggaag ttcatttaaa 7740 gtcctcccga atgagaactc cataggctgt ccaagcacat ccaatagcca gaatagcaat 7800 cgtattaggg gtaggcagat aggttactcc cataacagac caaagaactg ctaaagaggt 7860 tactcctgct atacgaagtc tgtttctgtt aaggatgata ccaagaagtt tgataaatcc 7920 agctgttaca aagaaagctg atataagttg tagatcaaaa agactggaga tgcggtcgta 7980 taaagcctca tgattaagtg tgtctatgtt taagtatagc cttacgccat acagaatact 8040 gactacggat agtcctatgc cgtgccattt caaatagagt attgaaatga ctttccgaag 8100 gggagtcgga agcttttcca taaggatttc tcccttcctt tagtagtttt ccagaaagcc 8160 atagtctagt tcttcgtcgg tctcttcgaa gtctgcttcc aaagcatcgt cctcaactgc 8220 ttcggcctgc ttaatttctt cttcgtcgtc ttccggctca gatatatcga ctatgatgtt 8280 taattcatta ttgacttgta cgtctggagt tagcaagtca tggaatttag ctagttgttg 8340 taaggcggtc agctggtctt ttgtagaaat ccttgcttga atcttatccc ctttagctgt 8400 gacaatctcg tcatagccat ctcgcttagc aatctttgta agatgctcca agacttctgt 8460 agcagtcatg atgtcagcgt tggactgctc agtaatcagc cattggatat acgcttttac 8520 atcagctcgc tttaataagc ggtgcccaga aga 8553 <210> 6 <211> 5804 <212> DNA <213> Artificial Sequence <400> 6 atcctccatt aagattacat cgaaaagctt gagcaactcg tccgtaaact cttgcccaga 60 ctcttcccaa agtttgataa acagttcttg atttttcgtc attattattc ctcctaaaca 120 tctgcacctg cgtatgtcgt agctatattt aaccaagacc ctttaccaac ttgttcatat 180 cttgaaccag aaccataccg gctcatgttg atagcacctc caggctctag cccaagtaag 240 tacctattca tgccagagcc ctgtgctata acgttggtag tttggttagg tcttgcccag 300 ataggtagaa taccaatctg tatgacatct gcactaccag ctattgggtt gatattcttg 360 aatgctccag caagctgtac tagccttccc agacgagtag cagtaggcca ttgaccagaa 420 ctagaagacg tgctatactg ttcaaatcca gaggcaggct gtagaccagt ccttggcata 480 ctgtaaaggt cgttgtagga aaacgaaccg cctttgccat ctttggtttg aagtgttagt 540 gcgtaaggag acaactgcat gttatattct aattgtccag aactatccaa ttgataagaa 600 gaaagggctt ggtggtcaat aattagctta cctgaaatgt ttttaactcc tgtagactta 660 aggtaggttt cccactcatt ggtatataaa ccgttactta gagtaagagt tcctcgttgc 720 caagttgtgg aaccatctgt tataggtcga tcataaggag attgaattgt caatccagag 780 agtgttccag aagttatgct agaggcactc aagttgatta cactaatctt tccagcatcc 840 agtgtaccag ttgtaatctt gctggctgat agagagccta tcttagcatc tgtgacagct 900 aggttagcaa tcttggcagt ggatacttgg aggtctccta tcttagctgt tgtaatagat 960 gcatcagcaa tcttggcacc gttgactgct aggttagcta tcttagcgtt tgacacagct 1020 aggtcagcta tgtgggcagt cttgataata gcgttgtcaa tcttagtcaa tccagtgatc 1080 caaacgtatt taccgtctat cagaactcct tccgaagaaa cattgatctg tgcaatgact 1140 ccattcttat caactttcaa attgatttgg tcagctaatt gggtaatctg ggaagaagta 1200 acgtttgtat tagcctcgta aatgtacatt tcatgaactt taatagttga tgaaggtggc 1260 acaaatagac tgaatcctgt ccactgagtt gatctaatag ttccttgcac ccatctatta 1320 ttagaatctg gaagagagaa tttaagattt tctccctcgg agaatcctat ctcgtaaggt 1380 ttatttatag aagcagagcc tacattaaca aacagtttaa cgttatagga ctttccgacc 1440 tccaaagcta gaggagggct tccccagtag attctagcag aacctgttcc attatttgtt 1500 acaagcaatc catctgctgc atatgagaag gtggctgtac tctctacggt aggctttgga 1560 ttctgtttct tgaagtctgg gtcagggaac ttattcgtca agtctgcaat gcctgtttga 1620 atctctgcaa cagttgtctt aagaccgttg gcagtctgtt caacttgtgt agctttagta 1680 aaagcattgt tggcagtagt ttgaacttct gatacagttg tcttaagacc ctccaccgta 1740 gcttctactt gagttacttt agcaactgtt gccaagtctg agtaagctgg ttgccatgct 1800 cgcaaagatg actcaccttt aaacatcatt agattcttta tacggaatcc agtggaggta 1860 gggttattag acaagttaac tactaaaaga acttttactt taccgcttct tacaggctta 1920 aatgtaatag aacgtgtgta gaaactagct gatccagcaa agacaggaat atctgggagc 1980 ttttgatttc cttgtccgtc ataatacatt aagaaacagt agtctaatac agaagtattg 2040 taaaagctcc caacttccag ttgtaaagtg tacgttgcat ctttctcaac atcagctatc 2100 agataatctg tttggattcc gtaactagtt gtagcagttc cttttgttac agctatctgt 2160 gtaccgtctg tagaaaaatt acctccaccc catactacat aacctttggt tgaatcccct 2220 ttagaattag gaataatatt agagtagtca ctatttaaga tgccttcttg aacagctgta 2280 atagtagctt tcagaccatc tgccgtagct tctacttgag tagcctttgc cagagctccg 2340 tcagcagttg tcttgacttc tccaacagtt actttcaaac catttacagt agtttcaaca 2400 gtagtagctt ttgaaagagc tgagtcggaa gttgttttaa cctgccctac agttacggta 2460 agtccatcaa cattcgtttc aacttccgta agcttctgag tagtctctcc ttgaactgtc 2520 tcaatgtctg agatggtagt tttcataccg ttaacatcat tcgtgacagt cgttactttg 2580 ctgtcaactt gaccaacctt tgtgatcgct gtagaagagt ctgttagagc tttagaggca 2640 tctgtctgag ccttgccaac atccgtctgg agtccttcaa catctacttg aatagcatct 2700 gcttgagctt ttgcattggc tgcatcagta actgcttgat tagctttgtc aagagctgct 2760 tgaccagctg ctgcggcatc ttgggcagct tctttagcag catcggcagc agcttgagca 2820 tctttacctg cttgagcagc ttcgttagca gcagcttgcg cttcttcggc atcctttgca 2880 gagtatcggt cttgccattc tccggtagtt tcattccata ttctaattgt tgaatacgtc 2940 ttaccagtat ctgggtcaac tgcatcaagg aaccagatat ctccttcttt aggatttgga 3000 gtaggcgtat ccccaacgct tacagaaggc acgtctccaa gctgtccaat gattccttct 3060 tggccttgtt gcaatactgt gatgtcctca gttacttgga caaccacttg actgatttgg 3120 tcttgctgat tttgaatctg attaatcata tcccgaagag ctaagacatc ttccgagtca 3180 gctgtggaaa tctctttgaa gttagtgaag gttacttggt cgtcttctgg attgttatga 3240 gaagttacca actcgactac ccgagcttcc aaacctaact ccatatcccc aactttttcc 3300 ttaagccata cagtatctcc tagatggatt tgttcagtcc cttcaaagcc caaagcattc 3360 tcaaggagta gtacgttaac tgtgtacgta tacgttggag caatgtagtc caacagctta 3420 ttacaagctt caagataagt tagttcgggg tctgttgaag acgacttcat gataaggact 3480 tttgcatagt ctccttggtc atagtcgttg tgagctgatt catgaatgat aatatccatt 3540 ggattgtctt tccggaatcc attaattttg ttaataggag agtatcctgc aagcgttcta 3600 acaacgtctt gttccatcca gtaaggaagg atggctgtat ggatattgtc gaagtctact 3660 gtacgctcaa tgttgattag atcacggtca tatacaaagt atttaccagt gttacttcca 3720 aagcgtttat agacatggag cactcttgtg atacgttgtc catcaaactt aacactaaag 3780 cgatactcta tgtcgtacag ctctcgtatt ttttccaaag tgcttcggac atccgtgtac 3840 tcttttacgt caactaactc gtagccgatg ttgattgtat cagatccgat aatatactcc 3900 caaggagttg ttcgtaaagc ccctgcaata gcatctcgta agttacctgc tgtgaaaggt 3960 accacgtgag actttaacaa agcatccaca gaggagtctt cacacaccac tcgtttgaga 4020 ggctgctctt gtgaccagtc ctcccacacg ttgatgatag taagctctct aagaacgttg 4080 tctttatctg ggtacaagac tgtgccgaat ccttccagcc attcactatc ttcgctttgg 4140 aggggtactg caaactcaag agtagtctgc attgtttcta agttgtcggt aaatttgtca 4200 tcaaaataag gagtagcgtt tggaatatta tttacgtagt ttccacgata tactccctgt 4260 ggacttaaga ctgtaatcat tgagtttcct cctaaagttt atttgtagcg attggtgtac 4320 tcatactcta ccttaccctt tactccagat attcccaaag tattcttgcc tggcttcaac 4380 gagaaccagt ctgtggaagg ctgtacataa gatggggcga ttgttccatt aagccatact 4440 tggcctttgg taaagtccac gataagctcg tcgtctttct tgaatgagcg agttatctga 4500 gggctgttgg caggcttttg caagatttcc cagcacttag tgtgatggac tgcccatcgg 4560 ttaatctgag gtctgttgtc aatgtttgca tacaagattc cataagctgc aaacttccta 4620 ttccaagtct cttgaggaag cgaacggaag cctgttgagc gtacgttctt catcattgat 4680 gagccgtatt gtaagtcaga gccaatcatt ggagaacgtt tctgagactt gaactggcct 4740 gcttgaagcc tccagcggtt gtccttacgc tcaatgataa tcttacctgc aaagttgtac 4800 cactctttac ctccccatcc ggggctgata cgaacttcat cttgagtaga tgagcccata 4860 gttgcaatat ggaatcgtat gcgtttctgc ttagctacat aaccaaaagc tacgtttgca 4920 aaaggtatca tctggtcgtc atataagatt atatacatat ggtggtcagt ccagtattgg 4980 ggatttccct tagttgagaa agcaacctct aaggcaaagt cattcaaggc tttagggtta 5040 accctcgtaa tacctccacc ataccatttg tacccaactg ttttacggtc tactttaggg 5100 aacttgttat tcttaagcat caatgttcca taagtagatt caagggttgt atttctgata 5160 aaatcttggt ataataagaa gctaggagtt gtattgttat ccatctgttt caatgcattc 5220 atgttgtcat agtactctga gaattgccaa ggcattgggt cgaagtttgt accagttcca 5280 gttccttccg acgagtcata accaagagtt acgttctctg actctcccat acctacaatg 5340 ttaaccattg gagaatcttc ttcaaaggtt attttcataa ctggatgagt ctctgctgtc 5400 ccctcattga agatttggaa gaaggttcct tcgtcagtat ccatagttac ttgcccagtt 5460 acttcgtctc cataggaggt tacttcgata caccggaagt tcaatgtgaa gtctcctaca 5520 ttaaggcttt gattgatctc agaggctcct tcaaatacga ctttccaaga acggtctttc 5580 gagtcggcaa atcgaatagt tgtttctcca atgtccaaga agttagccaa gtcttcaatt 5640 agatatggaa tatcctcttc cttattggct ttgataaagc agttcataga gataacacgg 5700 tctccataag tctttccata gttgaagttg cgtttgcctc tgtcataggc tgtcagaagg 5760 ttgttaacag ctggtagcac agagcggttg atgtctctta caaa 5804 <210> 7 <211> 5342 <212> DNA <213> Artificial Sequence <400> 7 tgttcgaggc ttcgtgtcat agactgggtc aaatagaaac ttaggtgtga ctgttgccga 60 caggtttagg tcagctagtg aagtagctgc tggcacgact actgacagat aaacccatcc 120 attgtcaaac gtatagtcgt ccaaaggttt ctcagaagat attgtccaag tgaaagttcc 180 ttgacttcca gtagactttc tagcaagctg tgtatcttca ctttctaagt atacttccac 240 attatgattg gcagttactg agaagagata ctcacgagtc ctttcacgga ctttggcaat 300 cttgtctgcc tcaatgtaac agtcttggaa gaactccgga aactctcttg caatagctcc 360 catcacatcg aatccaagag tgatctgaat accattctcg ggaatctgct gagactgtac 420 ataagttgtt ccagaagctg gggtaatctc tgtcatggag tctacgttat agggaatcca 480 tcctagagca tcgccaatcc cccagcccaa cgaaggggct aagggataag tcgtatgagg 540 agtatataca ggaacgtatg ttgagttcat cgtttcatct ttcctttcgg tcgattcgta 600 agcttggcat cgaactgctg ttgctcagtc atctttttag aggttgctct gacgatttcc 660 gtagtgtcta ggtaaacagg tacgatgatc tctggaatat ctcccccacc tgctgctcca 720 gaagctttca gctcgtctgc aatagctctt gcgaatggtc tcatgtaagt cccattctgg 780 attgggatga tggcttctcg acctctttca ttgtgtgtaa ccccctgtga aatgcctctt 840 tgtcccaatt ggttgcctgt tccaaaggct gtcatgttag ggttataggt agctgaacca 900 gaacctattc catagcctcc agctccactg acaagccctc cagaagcttt gcgagtgcct 960 gctccagaga ctagacctcc ccgagcttta ccccacttag aaaccttttc aacaatagtc 1020 ctagtggcgt ttacagctag gttgataacc cctccagcag gaattatact aattagattt 1080 tggatagctg tcataacagt gtcgaaccca gactttttag cctttacagt aatctcttta 1140 ccatctaccg agttagcttt agtctcgata ccttcgatag cctcaaccgt atcatcacgc 1200 atcgtctgag ctttatcaac cgtctcaatc atctgtgtac gagcatcttc aatcaactta 1260 tcacgagttt tcccagtagc tgctacagct tcatcggaca tgctcttgat ggcagcaaca 1320 gattggacat actgttgttg agctgcttgt acagtagagt ctctctgagc attggcatct 1380 tgaatagcct tatccttctg ctcttgtgtg attcttcctg atgagtctgc ctgagcttgt 1440 aaggctaaga tgacagaatc tttctgagct tgagttaggt caactacttg ttgagcattt 1500 tggcgggtca agctgtcaat ctgtgccaag gctgattcac gttctgagac agacatgctc 1560 ccaaggttag aatacagctc cagaatctta gtattgttag cagctatgga ttgttcttgg 1620 ttagcattgt gtgtggcttg ggcagccagt gccttggctt tagcatcctt gtcaaggata 1680 tcactattgt tgatgaaagt ggttaaggcg ttcatcttgt tggtattgct ttcttgaatc 1740 gttgtaagct gagtttgcaa agctgtctgt aagtcaggta atccagtttg aacggctgct 1800 gctatagcct tcgatggatt gtagttaggg tcagcctgcc atttagcagt ctctacagca 1860 acctgtgcac tagtagattg tagggttgat acaactgtac cagtagctac cgtaagctca 1920 tctagcttat ctgcggagat aaagctgaaa gaagctgctt gagcgtctag gtctttaaac 1980 acttggttaa ctaattcaat ctgctcctgc gccttgcttc caaacatggc tgaaataggg 2040 tcttgagttt ggacttccat gaggttgtct ttcatattta ccaaagcttc tgtaaatcta 2100 ctagcctctg tcgaagttgg gcgcaaagct tctgcccact catcccacgg cattttaact 2160 gttccaaacc atttctcata gtctttgatt ctgtcaaatt gtttagtaac tccatcaatg 2220 gcatcattaa ctaagtctaa acccttgtta gcaagttcta cacctttaag tccaatagta 2280 ccagtaatgc ctttaccaat ctttagctta agggcatccc aactatcttc taactggtcg 2340 agctgtcctt ccatagtctt acgcatctcc ccagcttgtt tagctgctgt acctgtggag 2400 ttaaccagtg attgaactag gtcgtctgtc tcttgattag tcttttgcaa gaccattgac 2460 ataccagctg caccagtctt accaaataag attgttgata gatctaggat ttcagctttg 2520 gacatgttct gagctgcgtt ctgtaagtct gcgataacgt ctgggatagg acgtgcctta 2580 ccttcggcat cttctaactt gattcctaat tcatctaaag cagccgctgc cttatcagtt 2640 ggggaagtta agtttgtaaa ggctgtccgg agagctgtac cagctttgga acctcggata 2700 ccttggtcag ccatgatacc agtataggca gcaagctgtt ccattgaagc tccccccaac 2760 tgagcagaag ctccggcata ttggaaggta tatcctaagt ctgtcatatc agctgcggtc 2820 ttgttagcag tctctgccaa aacatcggca atgtgttccg agtcgccagc tgctaggttc 2880 catgtattca aagctgcggc aacgatttga gcagttgtat caacagctga cccagaagct 2940 tctgctgcgt atacgatacc ctccattgca tcggctgtct cagtagctgt aaaacctaac 3000 ttggcaaagt ctaccatggc ctctacaact tcttgagcac ctttggaagt cttaccccca 3060 atttcgatag ccttgtcccc aagcatgtcc atatctgctt gagtacctcc agcaactatc 3120 tgaacctgtt tcaaagttcc ttcaaaggta gcatagcttt taactgcatc aatagcatac 3180 ttaccagcta tcttaacagc ctgtgaccca agcgagatag cagcagtcat tggagttagt 3240 ccagcagtaa aggtacctaa gcctgtgtta gccgataccc aagctttacc catccctaga 3300 atacctttct gagacttctc aacagtacca gtagttccag ataagacttt agcagactga 3360 gaaagcttgc tagtaacccc atcttgaacc tttcccatag actgcatggc tttgacgtat 3420 tggttattat ctacggaaac ctttattcgc atttccttat ctgccattat agttcctcct 3480 aatcaaacat attaaataca ttgtctaatt cttgtttggc aaaagctcta cggtcttcct 3540 cgtccatatc tctcagtaag tcttccgtag ttatctcgga ttctggaata tagtctaggt 3600 ctctgtaaag tttaaaacca acatattcgt cgtagcttat tggcttacct ttagcaggct 3660 gtttaaacaa ggtaaagaac agtccagcct ctcttgcatg acgttggtaa gctcctctca 3720 tcaatccatt aaactcatta ggagtgcttg tccagaaatc gttgactgaa atttctaagt 3780 ctgaacataa tatcatgaag tatcttacgt ctaaaagcgg agaatcgacg tcctccgacg 3840 tttctgggag acttttcttc atctgggtta ggctctttct caaagagttg tttaattata 3900 atactagatt gataactctg attgactttt tcgaagtatt ctgttaaagt aaattcatac 3960 tcatctagag acttttgtag aagatcagat acttccagta catctttgcc ctcatattcg 4020 ggaatgtttt gtagcatcgc ccagaataag tagagagact ggttaaaggg cgtttgctct 4080 gctacgaagt ctatgtaagc tttcccgaag gctaactcaa gaaagtggat tgatttataa 4140 gtcattcgca agtctatatt ctttccttga aattttatta gcatgtctag tcctccataa 4200 taaaaggggc tagggattta ttccccaacc ccttgattgt tattgccaag ctaatttaac 4260 agatgtcgca gtaacgtcgc ttgacattag gttgcttggt ggcgttactg ctatgcttcc 4320 tttaccacaa catctactgt tgtagagatt gctgtgttga ctgtcgaacg aacgttgata 4380 gatgctgtac cagcttttac accagttact ttaccactct gatctacagt tgcgatagat 4440 ggtactaatg aagtgtacgt aaccgactta tcggaagtat tttccggagt gaataccgga 4500 gtcagtgtag ctgttcctcc aactgtaata ccttcgggtg gtaccccatt tactgtcaag 4560 cctgttggaa agactgttgg agctacttgc tgctcttcca aagcaccttt accattgaat 4620 gtcaagctgt aagttacagc atcgtcataa ggtaagtcga tcgggaagtc tgtcagaata 4680 gcttgtccaa catatgtcaa gccagatggg aaatgaactc gtacacgtac acagtctcca 4740 tttacccaag ctgcgttcaa cgcttggaaa cctgcattgt cctctacgaa caatccgtca 4800 caatcgattg accaagactt ctggccttgc tcgttgtcag cccatccgaa accttctttg 4860 ttagtggtgt ccaaagtatc tgcggagcgg tttaatgtac cgcctcgttg ggctgctact 4920 ttagtccatt cgccagcttc atcttgaact tcaatcagaa cggctgtgcc tcgtacgaag 4980 cgtgatttac atacttctgc catgtgtatt ctccttttct tatcgtggat ttactaaaga 5040 gtctgcgact tcaaagtcta agaacaagta tcctcgattg tttttaaatg ttccattaga 5100 agcttcggta tagcgcacgt ggtcaagatt tgcattgact acgcaaaagc catcttccag 5160 ttctaatgga gagttaacaa gcctatctac caaaaagtct cccagagctt tagtctctat 5220 agagcttggg tagtcactcc ataagtggag cgttaagttg tgcatctttc cgtaagtatc 5280 ttttgaggtg actttaccag atgtcaactc ttcgccaatc tttacgtaag gtagttcggg 5340 ca 5342 <210> 8 <211> 4373 <212> DNA <213> Artificial Sequence <400> 8 tgtaaaatgg ataaatactc tccactagca cgtctctacg ccctagctat tgtaaaaggc 60 ttgggcggac ggactatcaa cagtgttcca tctagcttac gtgaagacgt tcaagcaatc 120 ttggacaatc atatggacga actaaaagca atgttatagg aggaagcctt atgcaaagaa 180 taaatttaga tacttctaga aaggctacca accaagacgt aaaggtttat atacgaactg 240 gggaaaagga gtttacaact atcggagtca gtcttacaac gtatggtatt ccgaacgact 300 tgactggctt cacggtaaac tttgaaggag ctaacgctga gggaagattc agtggtggag 360 gtgcaagggt tgtaaacgcc actaacggtc agattgaata caccttcacg cctaccgatg 420 cagctgtcga aggctggttc gaaacagctt acttcgtcat taagaaggga gatgaaatcg 480 agggcaccac agaggctttc cgagtccatg taagccgtcg ggtagacatt gatgatgcac 540 aggcagcagc tggggtaaat actctgcaag agactattaa cgccttggaa gctactttca 600 atgagtggaa agctgctcgg gaagctgatt atacaggact acagacacag gctgatgcac 660 tagccactca aataacttct gcaaaggctg acttggatgc taaggtagca gcagctcaaa 720 cagccgtcgg aacagctaag gcagaggctt tagcagcagt tgacgatgct gttgcaaaac 780 tgaatgcagc cattgaagat tttaatgcag ctgacttcta tactaaggca gaagccgatg 840 cactgctgtt gcaaaaggtt gatcgatcgt cttacgatgg actgtacaca acttctaaag 900 tagctatcac tccaatgagt ggatttgtgg aatacaatac caacagcgct tcggcaaact 960 ttccacaggc tatcagaagg tttggggtgg taactactaa aggagctttc aaaaacaatt 1020 cagaggtagt attgtcgggt aatgatgcca tatttaccat gggtcaactc ccagtagggt 1080 atcgcccggc agaggatttg aactttatcg cccaaggttc atggatgaac aagtatcttg 1140 ttactgttac taaaggtggt ctgataactg gcgcaaggta tggtactaac tctacagtaa 1200 acattccagc aggctcttgg ctaaatattg gaatgacctt cgtagcatta gaacaggaca 1260 cctaagtcat tttgtgggtc tatcccacag aggaggaatt aacatatgaa atacattaat 1320 aagagcgttt gtcgaggcgt agcaggacga cgtgccagag gatggaagcc tttaggtatc 1380 gttatccata atgacggtgg ctcaatgact ccggaagctt atgtagaatg gctggctgct 1440 aagtctacta cacagcttca agcaggcttt gctcactact atggtaaccg taacacaatg 1500 gctcgtgtag aagatactta caatggagct tggcacgtag ctaactacaa tggtaacatg 1560 gactatgtcg gatacgaagt ttgtgagtct ctgaaagttt ccgacaaaga cttcatcgca 1620 aacgaagaag cggtgttcca acaagccgct aaagacatga aagactgggg actaactcca 1680 tctcgtacaa ctgttaagct tcacagagcc tttgtaccga ctgattgccc gcaccgttca 1740 tgggcgttgc atgtaggtag aggggcagct gatacaacag ctaaccgcaa caagttggta 1800 gactacttcg tagctcgtat caaacactac atgggcggag gaagcaacaa cagcaactcc 1860 ggaagcaagc caaatactgg tggaaatagc ggaggcaaca agattaccaa tactactaag 1920 tttaataatg gagacaaagt aaaagtcttg gcaaaggcta ctaactatca gactggtcag 1980 tctataccaa gctttgtcaa aggtcagact tacactgtca aacaatctaa agtagttaac 2040 caatcagtct ccaaatacgc cttcctattg gatggagtta acagctggtt cttggcacaa 2100 gacttgcaga aagtctctgg gggctccact ggatatgctg ctaagaaagt tggggacaca 2160 gttactgtcc aaagctttgc ctcgcgctat caaacaggag aacctattgc cagctttgta 2220 aagggtaaaa agtataagat caagcaggtt aaatctgtca aacagtctaa gtcaaaacgt 2280 gcttacctgt tagatggaat ccagtcatgg gttcttgaac aagacgttaa atagcatagt 2340 aaaagacctc ccacagtttt tgtgggaggt ctttttgtta ctcttcggaa gcagcggtat 2400 tcatcttttc aaaagcttcg tcaaagctat caaacagctc gtcgaagttt tcaaggaacg 2460 tgtcaaagac ttctgcctca gctccggaaa gaggttcttg atagttatag gagatgtttg 2520 caatggcgtt taccaagtct tgggtagaca gctctccaaa ggttacttct tctttctgga 2580 gctctttcaa agcttcggta tactcgtctt gcacagcttt tggaatgttc caagaagttc 2640 caccagactc gttgacattc ttaattagat tgccatcatc atctcgttct ccaaactctt 2700 cgataagctc catctgctct tctgcataag cttcctgctg cttgttaagc cattttacaa 2760 agcgtgtgcg tttacgactc tcttggcgag ttaggttagg catgttgtaa aagattcgtg 2820 ccaagattgt aatatgagcg tttggaatct tagctgttaa aagttcaggt aaagtcattt 2880 aatcatcctc cataaagtta tatcaatagt atatcataca atcactaaaa tgtcaagcga 2940 atagatcttc caactcttcg gcagagagct cgttagggtc atggaagtct tttcgaccaa 3000 cctctgaaac agccttatca ataaacccat tccacttgaa ttgccgaagc tgcatgtatg 3060 aagctgtcgg aaaccttgca gagcctcccc aatctttaat agctaactcc atccacttct 3120 taagaacctc gtttccgtaa gcctccatat cagactttat gcgaattcta gtaagtttaa 3180 cattaagagt tgatggattc tgcttgaaat gaatcatatt aaggtagtcg agataagtca 3240 tgaaagtagt tgtattccac agctctattg gaagagcctc atagtcgtct gtcctaactt 3300 tgttaccttc tgaatcctta tataacttgt cgtctaatgt tcttgcccaa gccatttaat 3360 atacctccat tcatctaatg gaataatctt atcatatata atggagtctg tcaataggtt 3420 aggcgaagcc tagctgaggg tttcccgaag ctgatgtttt agctttaaag atccttgaac 3480 agactctccc ttaaacccaa ggacttctat cgaagccctg ttcacttcgt tcactaactt 3540 cttaacgttc agtttcactt cactaaggtc aaacccctta aaaccattat acaaatttac 3600 aataaatctg tcaagctata aatggagtaa atctattaat cttaaacaat tcttaataaa 3660 ctaacaaaaa taactccaat cgcttgactt cctccctata ttatggtata cttataaatg 3720 taataaagat taggaggaat aaattatgtc aaaaggatta gatgctattc agcgagttgt 3780 tgaacaggaa gcaaaagtag aacgtgaacc aagtcgattg acttatttga aaaaaggaca 3840 gagcattcgt gtacgcattc cagaggatat tgtagacaac ttgcatgtct ataaagtagt 3900 tagcgtgttc cagaaaatct taccaacgct ttcttacgca gcagagggac gttcagaacg 3960 tgacctttac aacgaagcgt tcgagatcat gcgagaagac tttgcaacag ctaaagctaa 4020 cggaactgta gcggctgacg acaaagaagc ttatcgaaac tccatgattc tacaacctaa 4080 accaactatc ctatttggag taattccatt agcggacttt gtacaaggca agaaagagaa 4140 cctttatgaa gccggacaac cgttgttgtt ggagactaac ttaggtaaga ataatgctaa 4200 cattgatgcc ttaacagcag ctttgacaaa gcctacgaac gctaagaaat ttggtagtcg 4260 tgcttttgaa attacttgca tcgcttctaa ccaatactct tttgcagctt tagatgagga 4320 tgagttagag cctaacgaga agaaagtatt cgaagaaact gctggagtat cta 4373 <210> 9 <211> 3568 <212> DNA <213> Artificial Sequence <400> 9 tgttaaatct actccatcat agtagtctgg agtctgtgag gaagtcatgt actgctgctg 60 tcgctctccg acttcttttc cttgaatttt aagagccatc tgtctcctcc ttccaacaga 120 ttaataagtc ctcattcgat agccccttta gaagctggag acgtcccatt ggagtattat 180 gagagtattt taatataatg gagtcaatca cttgacaaga tttttaaatt atgctataat 240 gcttttagag aaaaggtttt agcgctgtcg gtcgctgata ccgacggtac tccaagaagc 300 tgccttgcaa aagcctttag aaagcttatc cgaaactggg aaaaggaaag gaaggttttg 360 caatggagtt taaattaatt tcaaaaagct attgacaagt ctccaaagac gtggtaagat 420 agattcatag agctaaggaa gctacaatac gcctatgagt cgttgacagc cgtctgagga 480 gacttttatt atcttcttgg atgattaggt gtaagtggcg tagaacagct ctcagacaat 540 tttaggaggc ttattatgct gtatgagaat tttcagagag ctgtaaataa aggtaaagcc 600 gtccaagagg gtattcggct cataaagtac ctattgagaa ataaaggaac tgataaagaa 660 aactttctat gggctgagca aattatatca tcctataaac tgcgatttgg ggagcctcca 720 gaatccctct cagagtgggt atctctatta gctttggcaa acgatacggt aggatctatt 780 ggaggagata acaaatacgc taagtgcagt agttttgagt atagcttcta tagctttcgt 840 aagcaccgta gaatgaagac accctctgag aagtatgccc atgagtttcc gatggggctt 900 cttgaccatc tagctgtgga agtttcctta gaagatggat ggattgatgc catttacttg 960 acaactgaga tacttccatg gtatgataaa gaaagcttgt cactattcgt tgaaaggtac 1020 attcgagagt ctagtgttag agaaattgag aagtctttag gagtacctaa atcaacagta 1080 gctagaaaga tttctaggct agacaaacaa cttagtaaaa cattaggagg gtatttatga 1140 cagaatttaa agcaggcgac aaagtaaggt atttccaaga cttatcggaa agatatacaa 1200 ttgtatctcc agatattcct ataggagcta ttggagaggt tagaacagtg atcccggata 1260 gaagggtaga agaccccaat gtcatggttg gattggagca gggagaagtt atctggtttt 1320 atgcagacga actgcaatta gttgacgaag agactgatct accattcatt ccacaagtta 1380 ctcacaaaac tgtcctagat atttcactag atattaactt ggatgtgtac ctagctgctt 1440 tatcaaacat gaccacagct cgtaagcaga tggcggattt gtcattggac agataccttc 1500 cggaagctgt gcgagatgct ttggaggaac gattggataa taagattcaa gagtctggca 1560 aacaggctga ggaagctatt gcacggatgt ccaagatact ggaggtggag tagttgacag 1620 aatggagaga gctgcaaggg ttcactaagt atgatgaaga cggtcatctc aagtatacag 1680 gtatcgacga acaacttaca gagcttgcca attcctatga aattctaata gtgttctatg 1740 gagcgtttag ttcatctgat tggaatgtca tgagtggcgg cgatacaact gctttagtgg 1800 agctgagaaa ggctgaggtg aattaattga gaactaagaa gcccttgcca gaagaggaat 1860 atgcttatgt ggaaggatgg gatgagtttt gagtgagaat ggacttagca ttttaattag 1920 cttggtatca actgttgtga tatttatact tggaactgtg ttaatatact acgcaggagt 1980 atccttcgaa acccttatac tattcttaat aggtttttgt ttagtatggt ttattatttg 2040 ggctgttata gacatatcat tagagtaatg gaggtgccaa aatgaaagaa ttccgaaaag 2100 ctattaagaa actattttta caatatggag gactatgtac agcatgatta aagtttattc 2160 gaaaagaacc ttctgtgcag cttgcagaca aactaagtta gcctttgcaa agcagggtac 2220 agaatttgag gaaatagtag ttgacgaaac tgatgcagag atgttacaat tcttaaagag 2280 tcgtggccac agcagcttcc cagtcgttat cgtaagtgat ggcatggagt ggagtggctt 2340 tagaccagat catatcaaaa agtattccaa agactaggag gaagatttat ggaagtagat 2400 tatcaaccag ccggagcagg aaatgttaca ttaatgattg gacgtgttta tttaattaat 2460 gacaaactat atctatgtgt tgattgtgaa tcttttggag aatatcacta cgaccttgtt 2520 gagttggagt ccggaagagg agcctatcta agcagtctta atctaactaa tgttgacacc 2580 agtagccgaa gtggtctaag taacgaggta aatgccaact ttgacattgt tgatgtaaca 2640 gatgacgtaa aggtggtggc aaaatgatta cagtcctttc ggaagtcttc ccacagctta 2700 tcgaacgacg tatcaacaga cttcaaatcg aagccctgta tcacgacgac gaaggaaaag 2760 ctatcataga tggtcagata gccgcccctc gtggctctaa gacaggtacc caaggtatca 2820 aagggagtgt cgatagatcc agaatacccc aagagctgtg tgaacacatt gtaaaaatct 2880 gtgaggagga attgaaatga agtttgaagt aggagatgtt ttagtagatg cagggagaga 2940 tttagatgcc ccaatgagaa ttgtaaaagt ggtgtcacgc tcaaccgatt cttggggaga 3000 taagtattac ctaaagtatg gcgaagacct ttacatgtgg ttgtatgctt cggtggtaga 3060 ggacgaatgg aggaaagctc ctataggaac tgttgcatgg cttatccatg agctgtccaa 3120 gcacgatcct actgacagtg ttagtatttg ccaatggaac actaatgaat ggaaagttga 3180 cgtaaaagat gtagaaataa ttagtaaatt tgaggaaggg gaagtgactc tatggtaaat 3240 agaccaatga aatactccaa aggagactta ctgttagatt atgaaggaga cctttacaaa 3300 gtcctatcag tagattcgga aactaattgc tacgacattg gaggtttact cgacccatgg 3360 agtgatagat tagatgcaga cgtcttggaa cagtcattca caaagcttcc tgccggaact 3420 attggagagc tagtggagaa gctactggac tatcctgtgg atacacctat cagcatatat 3480 aggacatctg gctcagcaga tatttaccta gactccatca gcgacattga gatagactat 3540 gaggatactg gaggaattat cttatgct 3568 <210> 10 <211> 2903 <212> DNA <213> Artificial Sequence <400> 10 ctgattactg cgtagtagtg actaattcta ttcagtctgc aattgacaat gctctggaga 60 acataccaat ttatgaccac gttaaattat ccgaaattga tatttgtcac gttgagaaag 120 tggaggaata aagatgagag agtatagtca aagagattta tggagtgtgg ttaatggaaa 180 ggtagttatt ccagaagcta ttgcagacta tttggagagc ttccaaaggg gaggcatctg 240 gactatgaat gataaagagg atgctgcacg atgtatttgt aatgttggtt ggggacattg 300 ggtagaagga tctactggag aaaaatatga cttcggggaa gatcataaga agtatcataa 360 tatgtttgga ggagagactc gttttcatat ccttcgggca cttatggacg gctacgtagt 420 acatgcccca aaggttgctg taaggtttgg caagaagttt gcaaaatcat ccgaagtaga 480 ttcagaactc acttcaatga cttatcggtg gacgcctgat cgggaggatg agtacagcta 540 tacgagaagc tatgtactaa cgctttcaga ctaccctgag ccatggaatt acagagatgc 600 tttaatgcta caagaagatt ttggagggga gattgttaag tatggttaag aaactgtttg 660 aagtatatgt gacgtatggt aaaggtgacg gcgaagagct tcgggagagc tgggtggcag 720 aagatactcc agagaatcga gcagagtact tggataatct ttgttacagc gatgagtttg 780 ctgactctga gagcaacttc gtagacggaa aaagtaatat catgcactac tactgttatg 840 gtggagattg ggatgatcca acaggtggat ggttgcaggt aagaagttat gaggaaaagc 900 gagaagaact tgccaacgag tatgacaagg aagttaaacg gctcaaaaaa caattcggac 960 gtggagagtg attatatgag tagagcatta tctttagtag atattattga acagctgcct 1020 gacacgcctg tgggaacacg cttcgaaaca gactatggaa gcgagcttta tgtaagtact 1080 cagacagagc ctatgccaga cagtcaaaag gttcttaaat ggaagtccga tgacagggta 1140 gtaggtatta ccgaagtaac tgttggaaca acttaccact tgattccaga ctacgttgag 1200 attggctggc aggaagcttt tgaaatgatt aaggaagcta ctgaatcatt ccaccaacgg 1260 cttactggag ttttccttga gagtgccgac ggtttccgag agatttctat tatagatgac 1320 tttgaggaag acatttacgt tggagacttc atcgacttat tccgtatgaa attctataaa 1380 tctaataaat aaactttggg agacctattg acaggtctct tttttcgtgt tatgatagca 1440 tagtaaacga aaggggacaa actgtatgaa gatctcagtg aatgtgacat cagttaccga 1500 agataataaa gctaaggaaa agattaagaa agcagctaag gcaaaggaaa taccaactat 1560 ggaagagtcg tgggagctta tctatagccg taagaactct cctacagact tggcaagact 1620 ccaaaaggtg gaggaatggt ttaaggaagg aaagattggc cgagaagctg gcaaagagtc 1680 caaagccttt accaaagctg aggcactacg cctttacaaa gctatccaag aggctgaacg 1740 taaggaaaag attgaggaaa tggctactaa agagtgggaa aagtaccccc taatctctca 1800 agaagatgcc gaacagtggg ttgataactg tctgaacgct gacgacgact actttgcaat 1860 ggactttgaa acagtcggag ataacggtgg taagtataag taccgagagc aggtagcagg 1920 tttctcacta acctaccgat tcaatggaaa gcttgttaat ggctacttac caatcctcca 1980 ttacaaagag gcagtcgctg gagggtttgt tgaagatcct cggaacatta gtaaaggaat 2040 ggcttaccaa ttgattgaaa agctattcca cagccctaag aactccatct ggcataatgc 2100 aacgtttgac ttaggcttgg caaaggctgc cctaggcatc gaagcaactc atatgccgca 2160 tgatacaatg gttatcatga agctattgaa cgagaactta agcgacgttc ggacacctgc 2220 atttccaagc ggagtcggat atcagttgaa gaaccttgca gaatacttct tgaagattcc 2280 gtctgatact tttggagagc tgttcggaaa agatgctaag tttggctacg ttccattgga 2340 tgccgctaga tggtatggtg caaaggatac ttacgtaggc ttcttgctct ttgaatggca 2400 gatgaacatt cttaataagc ctagctttgc aaaaattaag aagtattatg agcgtattga 2460 acatccatgt atcaaagcta cttacatcat ggagtcagag ggctttgtaa ttgatgagag 2520 agaagtagcc aaacagcgtg aggaaggcta caagcactta gacgaactcc aagaggctat 2580 caaggagact ttcggggacg ttaacattgg ctctccgcag cagttgtcta agatgttgta 2640 ctttgaaaat gattggagca agtatgtgac acgtgataag aagtctatcc tcagcggtca 2700 tgtaggcttt gacgaccatt acattagcaa caaccgtaag tttgctttag ttgaaggcaa 2760 gaagctttta atcaatcctc gggtagttaa cggagagact attggagact ctctgccagc 2820 cgactcagat gctctgaaag ccattgccaa gcatcacgaa gaagtccagt tgattcttga 2880 ttggaaggat gagagcaagc att 2903 <210> 11 <211> 1712 <212> DNA <213> Artificial Sequence <400> 11 gaagtgttcc gagaaggcga tgccaaagat atgagaacta atatggcagc ttttgaacag 60 tggaagccaa ggttcttgga cggctacaac ctagaccacg tgataaagtt ctgggtagag 120 actccagaac agcaacaaca agaacaagaa cggctgttgg aagcagccag acatgggatg 180 gtggtaatag atgactgaag aacgccgagc agctattgaa cgagagattg aaaacttaaa 240 gtatgatcga aaagtcttgc gaaagcttta ctacaaactt gagggagtag ctccagaggt 300 agttctatca gatatagtta gtgatattta cctactagag gatagaattg taaggcttcg 360 tacggagaag cagctgattg aaaaggctcg tgaagaagtt ctctgcaaag ctgctgacaa 420 gactctccaa gagtatgctg acagggctac ggaaaaggat ttggaatcaa ctgctaaacg 480 ctttgaagaa gctcgtgcag aacatggcac tccatcgtgg aaggtagggg cattgatgca 540 ggagagccca gctaaaaagc agcggaagag tttagtaaga gctatcataa acctgctgga 600 cactaaatat aaataagcta atagagtcgc tttccaaagc tgtgggaagg cggctttgat 660 gagtatagga ggggaagtat ggcattcact tttcaaaata ctccggatgg aaaagtaata 720 gttgaccaag aaaggttacc aagtggcatg actgttagaa tagagtttca gctatatgat 780 ttagagaata ttggagtagc taatgtattt ctaaatgtat tccataagcg gaagcagatt 840 tctgataaca ctttgaaatc tacagggaaa gacggtgtat atccttttgt gtgggctatt 900 agaaagctta gggagtttga ggagtatgcc aaggaagaac tttgccacag cctgccgacg 960 tacatttaag tagactggga ggacaatcgg agaggtcgca tttataagag gttcctccag 1020 cgtgagggat atgtacttaa gaattttgga gaaggtagga agctgtataa gcagcttaac 1080 gttgatatca agtaagataa tagattgtag gaggaaagtt atttgaagcc aattagattt 1140 gaaggagttt atgacccaac tatttggaag cctgtcgaag gggctgaggg gtattttgtt 1200 aatatggaag gaaaggttaa ggggagactt gggagatttt tgaaagggac tcctgtaggg 1260 ggttatccat cattcaaggt aagcggcata ggacgatgtt tgttgatcca cagagctgtc 1320 gcccaagctt ttataggaga tattccagag ggctgggttg ttaaccatct taacgaagat 1380 aaaacaaacg ccaatgtaat gaatttggaa atttgctccc aaagccataa cataagacat 1440 tcagtagctt ccagaaagcc cccctcaaag caaggagcaa ttattgaaga tttatctggt 1500 tggaagccta tccctagcct ctcaacagct atggcacacc cctctgggag aattgcttca 1560 tttgacagat atggtaaatt aagggagcgc ttaggttacg tgaacattgg aggatataag 1620 gttgtatata tgaataggat gccgcataaa atgcacaggc ttattgcaga gactttttgc 1680 ccaaacccta acaactttcc aatagtcaat ca 1712 <210> 12 <211> 416 <212> DNA <213> Artificial Sequence <400> 12 ccgtactctt cttcacttgt ttcaaaacca tacataacgt ctgaaatctt atacaattgc 60 ccattccata ggattttttc cccttttctt ggaataaatg gtagcgccac aatatcaaat 120 ttttcagagt agttttcact gtttttgttt aaggtaatag ctaattcaat cgcgtacaat 180 tttcatatcc tccaaaaata ttaattaatt gaaaccacac gtacaggaga aaaacaactt 240 gcatttccct ttgaagtata aatttgagca accccattta ttctataagt tcctcctttt 300 ttatacgtcc aagtttgaga aatagtcaca ccaccagatt ttggggaata gcttcccgga 360 gaagtcgttt gtcccaaaat tccaatatta taaacagcgt tcactcggtt aattat 416 <210> 13 <211> 390 <212> DNA <213> Artificial Sequence <400> 13 ctgactattc agcaatttct ttttcaaatt catctaacaa ccgatcatag atctcggcat 60 ctttaccaga taacatgcca tcgtactcat tcaaaatccg tgggacttca tcaaagtttc 120 gcgcatacat accgccctca atcacaattt cttcatccat caaaatttct tgttctttat 180 tgaaagcagg tggcatatgt ggaaatagaa aagcaggtcc aagcgcatga ggagcggtta 240 aaacagcatg acaaagagtt ggggcgtctt aatgacatta cattagaaat gcaaaagtca 300 atgaacgaag gacttgcacg agttgatgaa tcaaatcgct tcttacgtga gcaaaacaca 360 cgacagagcg aacaaaatgc tgaaatcctg 390 <210> 14 <211> 387 <212> DNA <213> Artificial Sequence <400> 14 tgtccaagat tgcttgaacg tcttcacgta agctagatgg aacactgttg atagtccgtc 60 cgcccaagcc ttttacaata gctagggcgt agagacgtgc tagtggagag tatttatcca 120 ttttacattc ctcctgcaat taattctgag agctgtagaa cagtttcttg aagcatagca 180 acctgctgct ctaaaggtgg ttcgggaact ttttgaatac tttccataaa cttactcata 240 agctctgggt tgtcatggaa atcctccatt aagattacat cgaaaagctt gagcaactcg 300 tccgtaaact cttgcccaga ctcttcccaa agtttgataa acagttcttg atttttcgtc 360 attattattc ctcctaaaca tctgcac 387 <210> 15 <211> 346 <212> DNA <213> Artificial Sequence <400> 15 aaatttggta gtcgtgcttt tgaaattact tgcatcgctt ctaaccaata ctcttttgca 60 gctttagatg aggatgagtt agagcctaac gagaagaaag tattcgaaga aactgctgga 120 gtatctattc cagatgaagt attcgacggc tctctattcg aaagcaatac tgaaaaacaa 180 ttgaacgact tacgtttaat cggctttgac actactcgtt tgaaaggctt cgaaaacggt 240 cagcaagaaa ctggcacaat cgacatttct gacgaggata ttccattcta agaggggcgc 300 aagcctctcc tagtcttatt aggaggaact atggatacta ttaaaa 346 <210> 16 <211> 344 <212> DNA <213> Artificial Sequence <400> 16 ttattaatct gttggaagga ggagacagat ggctcttaaa attcaaggaa aagaagtcgg 60 agagcgacag cagcagtaca tgacttcctc acagactcca gactactatg atggagtaga 120 tttaacaacc cttaagccaa agatgaaacg ctttgcacag cattatgtag ctacggtaaa 180 cattgctgaa agctgtaggt ctgtaggcta caatgaatct tctgggcacc gcttattaaa 240 gcgagctgat gtaaaagcgt atatccaatg gctgattact gagcagtcca acgctgacat 300 catgactgct acagaagtct tggagcatct tacaaagatt gcta 344 <210> 17 <211> 334 <212> DNA <213> Artificial Sequence <400> 17 tctatagagc ttgggtagtc actccataag tggagcgtta agttgtgcat ctttccgtaa 60 gtatcttttg aggtgacttt accagatgtc aactcttcgc caatctttac gtaaggtagt 120 tcgggcattg ttttagttcc atcccagacg tttatacctt ctgctctgag agcttttacg 180 atagctcgtt gaagacttac ggaggaactt cttgcacgga ataatggtct actcataaga 240 atcctcctag atgttaattt tcataagctt atccaacatc ctgtccgtat actcttccaa 300 agctggtata aagtttgggt agttacgttc gacg 334 <210> 18 <211> 309 <212> DNA <213> Artificial Sequence <400> 18 ctggagtctc tacccagaac tttatcacgt ggtctaggtt gtagccgtcc aagaaccttg 60 gcttccactg ttcaaaagct gccatattag ttctcatatc tttggcatcg ccttctcgga 120 acacttctac agtgccgtca gaaagcttta ccatgaatct gtgcttaaat tttccatctt 180 ctagcataag ataattcctc cagtatcctc atagtctatc tcaatgtcgc tgatggagtc 240 taggtaaata tctgctgagc cagatgtcct atatatgctg ataggtgtat ccacaggata 300 gtccagtag 309 <210> 19 <211> 290 <212> DNA <213> Artificial Sequence <400> 19 tgacaatgga tgggtttatc tgtcagtagt cgtgccagca gctacttcac tagctgacct 60 aaacctgtcg gcaacagtca cacctaagtt tctatttgac ccagtctatg acacgaagcc 120 tcgaacattc cgttataatg gattgaaaca accttactac ctatttgtaa gagacatcaa 180 ccgctctgtg ctaccagctg ttaacaacct tctgacagcc tatgacagag gcaaacgcaa 240 cttcaactat ggaaagactt atggagaccg tgttatctct atgaactgct 290 <210> 20 <211> 255 <212> DNA <213> Artificial Sequence <400> 20 ggatgagagc aagcatttat cagcctttgt ggataagatt aaagacttca tagagcccga 60 cggaaagctt cacggagact tcaaacaggt tggtacagta actctacgct atgccgcagc 120 taacccaaac ctccaacagc aaccttacaa ggctcgtaat atgttcggca ttggagaaga 180 ttcgttaatc atgtcggcag acttctcaca gcaggagcca aggctcatga ctcatatgtc 240 taagtgtaag gctct 255 <210> 21 <211> 255 <212> DNA <213> Artificial Sequence <400> 21 tttccatagt tgaagttgcg tttgcctctg tcataggctg tcagaaggtt gttaacagct 60 ggtagcacag agcggttgat gtctcttaca aataggtagt aaggttgttt caatccatta 120 taacggactg ttcgaggctt cgtgtcatag actgggtcaa atagaaactt aggtgtgact 180 gttgccgaca ggtttaggtc agctagtgaa gtagctgctg gcacgactac tgacagataa 240 acccatccat tgtca 255 <210> 22 <211> 255 <212> DNA <213> Artificial Sequence <400> 22 cattacaaat acatcgtgca gcatcctctt tatcattcat agtccagatg cctccccttt 60 ggaagctctc caaatagtct gcaatagctt ctggaataac tacctttcca ttaaccacac 120 tccataactc tctttgacta tactctctca tctttattcc tccactttct caacgtgaca 180 aatatcaatt tcggataatt taacgtggtc ataaattggt atgttctcca gagcattgtc 240 aattgcagac tgaat 255 <210> 23 <211> 255 <212> DNA <213> Artificial Sequence <400> 23 tgacaaccca gagcttatga gtaagtttat ggaaagtatt caaaaagttc ccgaaccacc 60 tttagagcag caggttgcta tgcttcaaga aactgttcta cagctctcag aattaattgc 120 aggaggactg taaaatggat aaatactctc cactagcacg tctctacgcc ctagctattg 180 taaaaggctt gggcggacgg actatcaaca gtgttccatc tagcttacgt gaagacgttc 240 aagcaatctt ggaca 255 <210> 24 <211> 255 <212> DNA <213> Artificial Sequence <400> 24 ttattaatct gttggaagga ggagacagat ggctcttaaa attcaaggaa aagaagtcgg 60 agagcgacag cagcagtaca tgacttcctc acagactcca gactactatg atggagtaga 120 tttaacaccc cttaagccaa agatgaaacg ctttgcacag cattatgtag ctacggtaaa 180 cattgctgaa agctgtaggt ctgtaggcta caatgaatct tctgggcacc gcttattaaa 240 gcgagctgat gtaaa 255 <210> 25 <211> 255 <212> DNA <213> Artificial Sequence <400> 25 gccagtttct tgctgaccgt tttcgaagcc tttcaaacga gtagtgtcaa agccgattaa 60 acgtaagtcg ttcaattgtt tttcagtatt gctttcgaat agagagccgt cgaatacttc 120 atctggacta gatactccag cagtttcttc gaatactttc ttctcgttag gctctaactc 180 atcctcatct aaagctgcaa aagagtattg gttagaagcg atgcaagtaa tttcaaaagc 240 acgactacca aattt 255 <210> 26 <211> 255 <212> DNA <213> Artificial Sequence <400> 26 gcagatattt acctagactc catcagcgac attgagatag actatgagga tactggagga 60 attatcttat gctagaagat ggaaaattta agcacagatt catggtaaag ctttctgacg 120 gcactgtcga agtgttccga gaaggcgatg ccaaagatat gagaactaat atggcagctt 180 ttgaacagtg gaagccaagg ttcttggacg gctacaacct agaccacgtg ataaagttct 240 gggtagagac tccag 255 <210> 27 <211> 255 <212> DNA <213> Artificial Sequence <400> 27 gtgcagatgt ttaggaggaa taataatgac gaaaaatcaa gaactgttta tcaaactttg 60 ggaagagtct gggcaagagt ttacggacga gttgctcaag cttttcgatg taatcttaat 120 ggaggatgtc catgacaacc cagagcttat gagtaagttt atggaaagta ttcaaaaagt 180 tcccgaacca cctttagagc agcaggttgc tatgcttcaa gaaactgttc tacagctctc 240 agaattaatt gcagg 255 <210> 28 <211> 254 <212> DNA <213> Artificial Sequence <400> 28 ctcgggtagt taacggagag actattggag actctctgcc agccgactca gatgctctga 60 aagccattgc caagcatcac gaagaagtcc agttgattct tgattggaag gatgagagca 120 agcatttatc agcctttgtg gataagatta aagacttcat agagcccgac ggaaagcttc 180 acggagactt caaacaggtt ggtacagtaa ctctacgcta tgccgcagct aacccacacc 240 tccaacagca acct 254 <210> 29 <211> 252 <212> DNA <213> Artificial Sequence <400> 29 agaatataca aggcatattt gagaagccta ttctagcaac tattataggc gttactcaag 60 aagctattct ggaacgtggt tcacaactat ccgagtagct gttacgctaa ctgtttgtga 120 gtctgtctga tcgcctgata atagcttata atggagcgtg ttgcatggcg ttcgataggc 180 tgtcaagcac cttgccacag ctgtcagact acagtcaatc agtcaaacat aaacgtaaaa 240 cctatataga ga 252 <210> 30 <211> 251 <212> DNA <213> Artificial Sequence <400> 30 gttgctgttg gaggtttggg ttagctgcgg catagcgtag agttactgta ccaacctgtt 60 tgaagtctcc gtgaagcttt ccgtcgggct ctatgaagtc tttaatctta tccacaaagg 120 ctgataatgc ttgctctcat ccttccaatc aagaatcaac tggacttctt cgtgatgctt 180 ggcaatggct ttcagagcat ctgagtcggc tggcagagag tctccaatag tctctccgtt 240 aactacccga g 251 <210> 31 <211> 249 <212> DNA <213> Artificial Sequence <400> 31 tagataaaag agaagttgca ccattgattg gagtagcttc tttttatatc ctcttaaata 60 gctcacgaga agctctctca gacgtttcat tatagaatgg taacctacta ttagcctatc 120 atttgggaag cctgtcagat agcctattac gtcagctgtt cgtgagtctg tcgtgtgtct 180 cgtcggtcgg tcgtcggtca acgtgtgtcg agactgtcga acagttgagt caatgtgtct 240 tgtcaactt 249 <210> 32 <211> 245 <212> DNA <213> Artificial Sequence <400> 32 agcgcttagg ttacgtgaac attggaggat ataaggttgt atatatgaat aggatgccgc 60 ataaaatgca caggcttatt gcagagactt tttgcccaaa ccctaacaac tttccaatag 120 tcaatcagtc aaacataaac gtaaaaccta tatagagacg tcgaccaact gccgaccagc 180 tgttgatagt cttatggagt ggcttctgta ggctatcgaa cggctgttcg catatctatt 240 gatct 245 <210> 33 <211> 243 <212> DNA <213> Artificial Sequence <400> 33 catatctatt gatctagttt acataatgtg tattatacaa agttgacaag acacattgac 60 tcaactgttc gacagtctcg acacacgttg accgacgacc gaccgacgag acacacgaca 120 gactcacaaa cagttagcgt aacagctact cggatagttg tgaaccacgt tccagaatag 180 cttcttgagt aacgcctata atagttgcta gaataggctt ctcaaatatg ccttgtatat 240 tct 243 <210> 34 <211> 239 <212> DNA <213> Artificial Sequence <400> 34 ttatcagcct ttgtggataa gattaaagac ttcatagagc ccgacggaaa gcttcacgga 60 gacttcaaac aggttggtac agtaactcta cgctatgccg cagctaaccc aaacctccaa 120 cagcaacctt acaaggctcg taatatgttc ggcattggag aagattcgtt aatcatgtcg 180 gcagacttct cacagcagga gccaaggctc atgactcata tgtctaagtg taaggctct 239 <210> 35 <211> 237 <212> DNA <213> Artificial Sequence <400> 35 tgggttagct gcggcatagc gtagagttac tgtaccaacc tgtttgaagt ctccgtgaag 60 ctttccgtcg ggctctatga agtctttaat cttatccaca aaggctgata aatgcttgct 120 ctcatccttc caatcaagaa tcaactggac ttcttcgtga tgcttggcaa tggctttcag 180 agcatctgag tcggctggca gagagtctcc aatagtctct ccgttaacta cccgagg 237 <210> 36 <211> 226 <212> DNA <213> Artificial Sequence <400> 36 ttatcattca tagtccagat gcctcccctt tggaagctct ccaaatagtc tgcaatagct 60 tctggaataa ctacctttcc attaaccaca ctccataaat ctctttgact atactctctc 120 atctttagtc ctccactttc tcaacgtgac aaatatcaat ttcggataat ttaacgtggt 180 cataaattgg tatgttctcc agagcattgt caattgcaga ctgaat 226 <210> 37 <211> 226 <212> DNA <213> Artificial Sequence <400> 37 ttatcattca tagtccagat gcctcccctt tggaagctct ccaaatagtc tgcaatagct 60 tctggaataa ctacctttcc attaaccaca ctccataact ctctttgact atactctctc 120 atctttagtc ctccactttc tcaacgtgac aaatatcaat ttcggataat ttaacgtggt 180 cataaattgg tatgttctcc agagcattgt caattgcaga ctgaat 226 <210> 38 <211> 220 <212> DNA <213> Artificial Sequence <400> 38 cagcagctac ttcactagct gacctaaacc tgtcggcaac agtcacacct aagtttctat 60 ttgacccagt ctatgacacg aagcctcgaa cattccgtta taatggattg aaacaacctt 120 actacctctt tgtaagagac atcaaccgct ctgtgctacc agctgttaac aaccttctga 180 cagcctatga cagaggcaaa cgcaacttca actatggaaa 220 <210> 39 <211> 220 <212> DNA <213> Artificial Sequence <400> 39 cagcagctac ttcactagct gacctaaacc tgtcggcaac agtcacacct aagtttctat 60 ttgacccagt ctatgacacg aagcctcgaa cagtccgtta taatggattg aaacaacctt 120 actacctctt tgtaagagac atcaaccgct ctgtgctacc agctgttaac aaccttctga 180 cagcctatga cagaggcaaa cgcaacttca actatggaaa 220 <210> 40 <211> 218 <212> DNA <213> Artificial Sequence <400> 40 ttttaatagt atccatagtt cctcctaata agactaggag aggcttgcgc ccctcttaga 60 atggaatatc ctcgtcagaa atgtcgattg tgccagtttc ttgctgaccg ttttcgaagc 120 ctttcaatcg agtagtgtca aagccgatta aacgtaagtc gttcaattgt ttttcagtat 180 tgctttcgaa tagagagccg tcgaatactt catctgga 218 <210> 41 <211> 216 <212> DNA <213> Artificial Sequence <400> 41 tagcaatctt tgtaagatgc tccaagactt ctgtagcagt catgatgtca gcgttggact 60 gctcagtaat cagccattgg atatacgctt ttacatcagc tcgctttaat aagcggtgcc 120 cagaagagtc attgtagcct acagacctac agctttcagc aatgtttacc gtagctacat 180 aatgctgtgc aaagcgtttc atctttggct taaggg 216 <210> 42 <211> 215 <212> DNA <213> Artificial Sequence <400> 42 aacactgttg atagtccgtc cgcccaagcc ttttacaata gctagggcgt agagacgtgc 60 tagtggagag tatttatcca ttttacattc ctcctgcaat taattctgag agctgtagaa 120 cagtttcttg aagcatagca acctgctgct ctaaaggtgg ttcgggaact ttttgaatac 180 tttccataaa cttactcata agctctgggt tgtca 215 <210> 43 <211> 215 <212> DNA <213> Artificial Sequence <400> 43 aacactgttg atagtccgtc cgcccaagcc ttttacaata gctagggcgt agagacgttc 60 tagtggagag tatttatcca ttttacattc ctcctgcaat taattctgag agctgtagaa 120 cagtttcatg aagcatagca acctgctgct ctaaaggtgg ttcgggaact ttttgaatac 180 tttccataaa cttactcata agctctgggt tgtca 215 <210> 44 <211> 215 <212> DNA <213> Artificial Sequence <400> 44 aacactgttg atagtccgtc cgcccaagcc ttttacaata gctagggcgt agagacgtgc 60 tagtggagag tatttatcca ttttacagtc ctcctgcaat taattctgag agctgtagaa 120 cagtttcatg aagcatagca acctgctgct ctaaaggtgg ttcgggaact ttttgaatac 180 tttccataaa cttactcata agctctgggt tgtca 215 <210> 45 <211> 206 <212> DNA <213> Artificial Sequence <400> 45 tctatagagc ttgggtagtc actccataag tggagcgtta agttgtgcat ctttccgtaa 60 gtatcttttg aggtgacttt accagatgtc aactcttcgc caatctttac gtaaggtagt 120 tcgggcagtg ttttagttcc atcccagacg tttatacctt ctgctctgag agcttttacg 180 atagctcgtt gaagacttac ggagga 206 <210> 46 <211> 206 <212> DNA <213> Artificial Sequence <400> 46 tgttttagtt ccatcccaga cgtttatacc ttctgctctg agagctttta cgatagctcg 60 ttgaagactt acggaggacc ttcttgcacg gaataatggt ctactcataa gaatcctcct 120 agatgttaat tttcataagc ttatccaaca tcctgtccgt atactcttcc aaagctggta 180 taaagtttgg gtagttacgt tcgacg 206 <210> 47 <211> 201 <212> DNA <213> Artificial Sequence <400> 47 gcagatattt acctagactc catcagcgac attgagatag actatgagga tactggagga 60 attatcttat gctctggaaa atttaatcac atattcatgg taaagctttc tgacggcact 120 gtagaagttt tcagagaagg cgatgccaaa tatattagaa ctaatatggc agcttttgaa 180 cagtggaagc caaggtaagg t 201 <210> 48 <211> 201 <212> DNA <213> Artificial Sequence <400> 48 gcagatattt acctagactc catcagcgac attgagatag actatgagga tactggagga 60 attatcttat gctcgaagat ggaaaattta agcacagatt catggtaaag ctttctgacg 120 gcactgtcga agtgttccga gaaggcgatg ccaaagatat gagaactaat atggcagctt 180 ttgaacagtg gaagccaagg t 201 <210> 49 <211> 181 <212> DNA <213> Artificial Sequence <400> 49 ctactggact atcctgtgga tacacctatc atcatatata ggacatcttg ctcatcagat 60 atttaactag actccataag cgacattgag atagactatg aggatactgg gggaattaaa 120 ttttgatcga agttggaaaa tttatgcaca gattcatggt aaagctttct gacggcactg 180 t 181 <210> 50 <211> 176 <212> DNA <213> Artificial Sequence <400> 50 taccagatgt caactcttcg ccaatcttta cgtaaggtag ttcgggcatt gttttagttc 60 catcccagac gtttatacct tctgctctga gagcttttac gatagctcgt tgaagactta 120 cggaggacct tcttgcacgg aataatggtc tactcataag aatcctccta gatgtt 176 <210> 51 <211> 176 <212> DNA <213> Artificial Sequence <400> 51 taccagatgt caactcttcg ccaatcttta cgtaaggtag ttcgggcagt gttttagttc 60 catcccagac gtttatacct tctgctctga gagcttttac gatagctcgt tgaagactta 120 cggaggaact tcttgcacgg aataatggtc tactcataag aatcctccta gatgtt 176 <210> 52 <211> 176 <212> DNA <213> Artificial Sequence <400> 52 taccagatgt caactcttcg ccaatcttta cgtaaggtag ttcgggcagt gttttagttc 60 catcccagac gtttatacct tctgctctga gagcttttac gatagctcgt tgaagactta 120 cggaggacct tcttgcacgg aataatggtc tactcataag aatcctccta gatgtt 176 <210> 53 <211> 167 <212> DNA <213> Artificial Sequence <400> 53 tgctcaagct tttcgatgta atcttaatgg aggatttcca tgacaaccca gagcttatga 60 gtaagtttat ggaaagtatt caaaaagttc ccgaaccacc tttagagcag caggttgcta 120 tgcttcatga aactgttcta cagctctcag aattaattgc aggagga 167 <210> 54 <211> 166 <212> DNA <213> Artificial Sequence <400> 54 cacagactcc agactactat gatggagtag atttaacaac ccttaagcca aagatgaaac 60 gctttgcaca gcattatgta gctacggtaa acattgctga aagctgtagg tctgtaggct 120 acaatgactc ttctgggcac cgcttattaa agcgagctga tgtaaa 166 <210> 55 <211> 166 <212> DNA <213> Artificial Sequence <400> 55 tttacatcag ctcgctttaa taagcggtgc ccagaagagt cattgtagcc tacagaccta 60 cagctttcag cattgtttac cgtagctaca taatgctgtg caaagcgttt catctttggc 120 ttaaggggtg ttaaatctac tccatcatag tagtctggag tctgtg 166 <210> 56 <211> 164 <212> DNA <213> Artificial Sequence <400> 56 gccagtttct tgctgaccgt tttcgaaccc tttcaatcga gtagtgtcaa agccgattaa 60 acgtaagtcg ttcaattgtt tttcagtatt gctttcgaat agagagccgt cgaatacttc 120 atctggaata gatactccag cagtttcttc gaatactttc ttct 164 <210> 57 <211> 164 <212> DNA <213> Artificial Sequence <400> 57 gccagtttct tgctgaccgt tttcgaagcc tttcaatcga gtagtgtcaa agccgattaa 60 acgtaagtcg ttcaattgtt tttcagtatt gctttcgaat agagagccgt cgaatacttc 120 atctggacta gatactccag cagtttcttc gaatactttc ttct 164 <210> 58 <211> 162 <212> DNA <213> Artificial Sequence <400> 58 tccgttataa tggattgaaa caaccttact acctctttgt aagagacatc aaccgctctg 60 tgctaccagc tgttaacaac cttctgacag cctatgacag aggcaaacgc aacttcaact 120 atggaaagac ttatggagac cgtgttatct ctatgaactg ct 162 <210> 59 <211> 156 <212> DNA <213> Artificial Sequence <400> 59 ctgattactg cgtagtagtg actaattcta ttcagtctgc aattgacaat gctctggaga 60 acataccaat ttatgaccac gttaaattat ccgaaattga tatttgtcac gttgagaaag 120 tggaggacta aagatgagag agtatagtca aagaga 156 <210> 60 <211> 150 <212> DNA <213> Artificial Sequence <400> 60 cctgcaatta attctgagag ctgtagaaca gtttcttgaa gcatagcaac ctgctgctct 60 aaaggtggtt cgggaacttt ttgaatactt tccataaact tactcataag ctctgggttg 120 tcatggaaat cctccattaa gattacatcg 150 <210> 61 <211> 150 <212> DNA <213> Artificial Sequence <400> 61 cgatgtaatc ttaatggagg atgtccatga caacccagag cttatgagta agtttatgga 60 aagtattcaa aaagttcccg aaccaccttt agagcagcag gttgctatgc ttcaagaaac 120 tgttctaaat ctctcagaat taattgcagg 150 <210> 62 <211> 143 <212> DNA <213> Artificial Sequence <400> 62 gttgctgttg gaggtttggg ttagctgcgg catagcgtag agttactgta ccaacctgtt 60 tgaagtctcc gtgaagcttt ccgtcgggct ctatgaagtc tttaatctta tccacaaagg 120 ctgataaatg cttgctctca tcc 143 <210> 63 <211> 140 <212> DNA <213> Artificial Sequence <400> 63 gtaagctaga ttgaacactg tttatagtcc gtccgcccaa gccttttaca ctagataggt 60 agtagagacg tggtagtggt gtgtatttat ccattttcca ttcctggtgc aattaattct 120 gagagctgta gaacagtttc 140 <210> 64 <211> 131 <212> DNA <213> Artificial Sequence <400> 64 tcctcctgca attaattctg agagctgtag aacagtttct tgaagcatag caacctgctg 60 ctctaaaggt ggttcgggaa ctttttgaat actttccata aacttactca taagctctgg 120 gttgtcatgg a 131 <210> 65 <211> 130 <212> DNA <213> Artificial Sequence <400> 65 gacagactca caaacagtta gcgtaacagc tactcggata gttgtgaacc acgttccaga 60 atagcttctt gagtaacgcc tataatagtt gctagaatag gcttctcaaa tatgccttgt 120 atattctcat 130 <210> 66 <211> 128 <212> DNA <213> Artificial Sequence <400> 66 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 60 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 120 gggggggg 128 <210> 67 <211> 128 <212> DNA <213> Artificial Sequence <400> 67 tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt 60 tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt 120 tttttttt 128 <210> 68 <211> 128 <212> DNA <213> Artificial Sequence <400> 68 taatgcttgc tctcatcctt ccaatcaaga atcaactgga cttcttcgtg atgcttggca 60 atggctttca gagcatctga gtcggctggc agagagtctc caatagtctc tccgttaact 120 acccgagg 128 <210> 69 <211> 19905 <212> DNA <213> Artificial Sequence <400> 69 ttcatgcttg ggataattaa tttcatacgt ccatcaattg aaagtcctaa tgaacttgct 60 agagacttta gttgtttaga tgtttcattc ataaccttaa aggcgcctga tggtttccct 120 ttttcgtgca aaattcctaa aatgaaaagt aataaaggta aaaagtacct aaactaataa 180 aggtaaaaaa tacttttatt aataaaagta aaaaatacct aaattcaaaa ataagttacg 240 attcctaaaa caaatatttt tatgctatac ttgaaacaaa gacatattta ggaggagagt 300 aacatggcaa gacctagaaa actaatcagc gcacaagata atagtcattt aacaaaagag 360 gagcgtattg agcgcgagca agaagaacaa gagttatata attatgaaca actttcatta 420 gacgatattc ctgagggaat tactaaggaa gggtggttga tttacgagga ccttgttcca 480 caacttaaac agctaccaat ttcaaaacta gacgctggca tgctagtcat ttattgtaat 540 acttacgcta tttacagtca ggcaactcaa gaggtatctg aatacggtta tcttgacgaa 600 aaagggaaac catcaggcgc ctttaaggtt atgaatgaaa catctaaaca actaaagtct 660 ctagcaagtt cattaggact ttcaattgat ggacgtatga aattaattat cccaagcatg 720 aaaacgaaag aacaaccaga cccgtttggt gacatgttat aatgtttcat gtgaaacaaa 780 ggagtgatac agcaaatgag taaggactat gtaaaaattt acattgacaa agtaaaggcg 840 ggaaaatatc ctgtagggaa acgtattcag ttagctattg agcgacatga acgggactta 900 gagaggtcaa aatacccatc gtttccgtat gaatatagac cagaattagc agaaaaacca 960 atcgctttca ttgacaacct accagacccc aaaagcggta agagggtagg actagcagac 1020 tttcagaagt tcattattgg tatgatattt tcatgggtta aaaaggactc agggtacagg 1080 cgatttacta aagtggtaat ctccatgagt cgtaagaacg gtaaatcatt attaatcgcg 1140 ggtattgcat tatatgaact tctttacgaa cgttcgccaa tggcgtcccg tcaaatatat 1200 tctacagcca atacaaaaga ccaagcgtct atttgtttcc gcatgattaa gacacaacta 1260 caggctgtta gaaagaaatc taaaaaggtt cgtgagttta caaaagtaaa caaatatgac 1320 attgagacaa aagatgactc tttttgtaaa gctctagcct cagactcatc tgtattagat 1380 gggttagatg tttgttgctc catctttgat gaaatggctg agaataaaga tacttctatt 1440 gttgaggtta ttgagtcatc tcagtcacaa caattacaac cccttaactt aatgattagt 1500 acaacctcac aaaacctaaa cggacactat catatggagg aatatccaat gactatgaaa 1560 gtattaacag gtgaggtaga ggctgaacac tacttagctc tatggtggga aatggatagt 1620 tttgacgagg cggatgacga ggaaaactgg tttaaatcta accctctttt tgaaaaacct 1680 gacgttcgca cacatatgtt agaacacaaa cgggctaaaa agacagaggg agaggctaaa 1740 ggtaatctca ccaacttcct aactaaggag cttaattttt gggttgcgga ccaagcaacg 1800 tcatacattt ctgtagacga gtgggaaaag gcgtacacag acgaggagtt tgacatcaca 1860 gggcgtgaag tatttattgg tatagaccta gcacgagtaa atgacttgac cgctgttacg 1920 tgggttattc ctatccctga aaaagaattg tttattgttg actctcacgc gtgggtagca 1980 acaacgggtg gtggtattgt tcagaaagag gctaacgata gaacacccta tagacaatat 2040 tccaaacagg ggtattgtga aatttcttcc cgtcctgacg gtcagtgtga ttgggaggat 2100 atgttaaatt gggttttggc gtttattgag acaaacaatt tagacgtaca aggtatttgt 2160 tatgaccctg cacagtctca attaattacc acaagactag cagacgggta tgaggacgta 2220 ctctttgatg tacgtcagtc ttatatgcga ttaaacccac ctactaaaca attacaagtg 2280 gatatacgag cgggcaaggt ccttcacttt aacaaccctc tattgacaag agccgtgtac 2340 aacgcattta caaaagagtc aaacgattta attatgattg ataaacaagt taaccgcaac 2400 aagattgacc ctcttgacgc gcttataaac gcgtacagtg aagcatactt ttatgagttc 2460 gaggaaataa actggtcaga acgttacgca agcggtgatt ttggttttgg actgtaataa 2520 acgaacgagg caacccaact agggttgtct ttttcgtgtt ataatttata aagaagttat 2580 aattggagga ggttcaccat ggaacgaatt atatatttac ctatgattat gtatatacta 2640 gcgtgtgttt ttatggctat tggtgccttt ttggtagata taaccgtagg ttttatggta 2700 ttaggtggcg cttgtttggc tacaagtttt aagctatcaa aggaattaga gcaggttgat 2760 aacatcaacg ataaaggaga gagtcactaa tgggaatttt tatcagaaac aagccacacg 2820 aagagcgggc aaatctatac cccgtagcac catcaccaat ggttgtggac tttggtactt 2880 ttattacagg gcaatcacta gacgagattg aacatttaaa aaattctgac atttacacag 2940 caacaaacat tatcagtggc gatattgcta aatgtttgat tagagagcga ccggatggaa 3000 ttgtaagtaa acctcagatt gtaaatatct tgcgtagtaa accagataca aacctaacgt 3060 cctacggttg gttgtatgct attaccatgt ataccctttt atatgggtct gcgtttgcaa 3120 tcattagacg caacggaaca caagttacta agctacagat tgtcagccct catacaatta 3180 caatcttaca agacacagcg agtaaagaat tgtcatatga gtacattgac cctgacaatc 3240 aaaagaaaga aaccatcaag ggtaaagaca tgttacattt tagactgaac tcaattgacg 3300 gcatttcagg acgctcacca ctaaaagcgc tagtacctga aatagatatg caaacaagcg 3360 gaacacgttt gttaggtagt tactttaaaa aaggtatctt tggtggtgct atcttaaaac 3420 taacaaaagg tagcgtgaat aacgatgtca aacgccaaat taaaaaagat tttgagtcca 3480 ttaattcagg aacacagaac gcaaacagtg tactcgtatt ggacagcaca caagagtatg 3540 aaacatttac ggttaataca gacctattga aactaattca gtctaatacc tttagcacaa 3600 aacaaatagc taaagtgttt ggtatacctt taaatcgttt tggtatggag ttagtaaact 3660 cacaagacgg aacacaaaac tctatttaca ttgctagtac cttatcagga tatgcgagaa 3720 tgatatgtga tgagttaaat cttaaattaa atattgacgt ggaactagac tttgctagtt 3780 tattaaacga tacattagac gaacgcaaaa aacgaatgtt tgagggtaca gccaaaggca 3840 ttgagtatct taaacctaac gaggtacgcg cctactatgg ttatcctgaa acagacgaga 3900 gtcagttttc tagaatgaca ggctcacgta ttaatgtttc acgtgaaaca aacaatcaaa 3960 ataaggaggc tactaatgat gaaaacggag acgcgtagca ttgagattag agcacttgag 4020 gaaaatgagg acatgattgt tgagggttac gctgttacgt tcaacagtga aaccaacctc 4080 tatgagaacg tatatgaaca aattagttca aatgctttta atggggttga cttctcagac 4140 gtccgcgcat tttatgacca tcaatcaggt aacttattag gacgaacaaa gacaggtacc 4200 ctacaattaa acacagacga cagcggttta aagttccgtc tacaattacc aaatacccaa 4260 ttaggtagag acgtctatga gttagtaaaa cgcggtgacc tatcacagtg ttcgtttggg 4320 tttatggtta aaagtgatac gtggtcatac aacgcaaaca cagacacata tcaccgcaca 4380 attgaccaaa ttggtagatt ggtagagatt tcactagttt caattcccgc atatgatgat 4440 acaactgtag cagtggcaca acggtcacaa aaagcgttta aagaacaaaa aagaaaatta 4500 gaattagaac ttgacatttt agaattaatg tgatacagct aactcacccg cggttaataa 4560 acgcgtgtta taattattta agaaacataa taaggagtgt gaaacatgga taaacgatta 4620 ctagaagccc gtgaacttat cgcacaaggt aaattagatg aggcggataa attaatcaag 4680 gaaattcgtg aggcacaaga cgaacaaaca gacgaggtta accctgacga gcaacctaag 4740 gatgaacaac ctaaggatga tgaggcagac gaggttgaac cagaagaaaa taaagataaa 4800 tctgtggacg cggaacgtgc taaagcatta gaggaagacg tggacaaatt agaaaaagga 4860 gaggctagaa gtatggaaaa tgtaaagaaa atcaacccta cagaaaacgt tgctgaagct 4920 gaggttcgtg cgttcggtga atatgtacgc tcacacggtt ctgtaaaagc acctgagtta 4980 cgggatatta aattagaggg cgttgaggca attgttccgg ttgaccgcat tactcaacct 5040 gtaacattac ctgagacaat cgtagaccta caaaactata tcaacgtagt aacagttagc 5100 acaacgtcag gttcttaccc tattttggaa acaactaacg cggtaatgaa cacagtagct 5160 gagttagtag aaaaccctaa attggcagaa ccaacattca aaaatgtaga atggaaggta 5220 gaaacacacc gcggatatat tccaatgtct aacgaagcaa ttcaagactc tgaccctgac 5280 ttagttgcgt tgattgctcg ccacttaaca cgtattgggt tgaacacaat caataaagca 5340 gtaatgactg agttactagc taagttcgaa gcaacagaag taacttctct tgatcaattg 5400 aaaacagcgt caaacgtaac aattgaccct gcttacaatc aacgagtttt tgtttctcaa 5460 agcgcatttg ctcaattgga tacgttgaaa gacgcagacg gacgatacat tattcaacca 5520 aacgtagcaa tggcaagtgg taaaacattg tttggtaaag aggtaattgt acttcctgac 5580 gctatcttta aaaacgacac aaatgataaa ctattattca ttggtgactt agaacaagct 5640 attactttgt tcaaacgtac tgaaatgacg gtacgttggc aagaccacaa tgtctacggt 5700 gaaatgttag cgggtgccat ccgttttgac gtagtagcta cagacacaaa ggcgggctta 5760 atgttcaaat taggagctat tcctaacaac gtttctacgg taacagtagc aaatgcgtct 5820 gagttcccta gtggtggagc aggagcctaa taactaaccc attgaggggt aaggggtaaa 5880 acctcttacc tcttttttat tagataggag tgagataatg ctaacaattg accaaattaa 5940 aaataatcta cgcattgacc ataatatgga tgacgagtat ttaacaatgt tacaagaaac 6000 agcagtttct tttttgatgg gagccattga ggtaaaggac caaccaacgg acccacgctt 6060 tgatattgct acaatgtttc taattgccca ctggtatgaa aatagagagg gagtaagcgg 6120 tagccaattg tctgagattc cgtttggagt gacagcactc attcatcaat tacgaggctt 6180 accacgtcct gaggagtttg ataattatgt cctttagaaa atacagtaag ttaaaagacc 6240 gtattactat tcaaatcgcc aaaaaaggta aagacgaaaa ttaccaacct acagtaatct 6300 atgaggactt actatcttgt tgggcgtctt ttgagtctca atatatgcgt gataaagtaa 6360 agactgcggg tacaacttta gaaaacgctg ttaacttcat tgtaaggtat gaccaaaaga 6420 aacagattca gcgagaccat tatattttac acaacggtgt acgctatcgc attgaggatg 6480 tttcacgtgg aacatacagc aaagactttg atactttgat tgctaaggag gtttctaaag 6540 aggacgtttt aaatgaggtg gtaaaatgag tgataattat gtagacttta gtgacatcta 6600 caaagcgctt ggtgaactag gtaaagactt agaccgtgag gcaaataaaa taatgaacga 6660 catagcgcct gaggttgctg aggaatttag caaacgcgta ccatactggt ctaacagtaa 6720 agcaaaaatg agcggtaagc gtggttcata tatgggtgag catatgagag accatgttat 6780 ctatagcaaa gccaaagatg gatatgtaga aattggcttt gatgatgagg ttgcgtggcg 6840 cgcgcacttt attgagtttg gaactatcaa acaaccacct caacacgtga tagaaaagtc 6900 tttagacgca ttgtctaaag atgtacagaa acgtgtagag gatgaattta ggaggcgtta 6960 tatgtgaaac taactacaac actaattgcg gataaactaa gtcaagccta tccagatata 7020 gactggtacg taaactttgt tcctgaggcg gagcaaacaa ttcctaactt accattaggg 7080 cgaattactg agattggata tactcacgac tcttatgcaa gtaataaccc cctaatgatg 7140 gagataacca tacaggtaga tgtatggtgt aagacactat cagaggcgca aaatatttac 7200 tatgaaatgg acaaactatt ttcaggaaac tacaatagtc tatcatatag tgaaattggt 7260 actgaccctg atattgagaa cgcaccacgt atcattaaac gctatatcat cacaagagac 7320 ataaagctag tctaactttg aacgaaaatc atgtgttaaa ataatataag aaagacaaga 7380 aaggatgaca caaacatggc aaaaatcggt tttaaatctg ctcatattca tgtgcccaat 7440 aacgagggta caggctacac aacctacaac cttgacaaaa ctaaaggcgg tgcaattgag 7500 gcaacaatca gtggactagg agcggaggct actacagtct acgcgtcaaa cgttccgttt 7560 ttcgtatctg ctaaaggtac aggtgaaaca accgtatcat tgaatgtttt cgacttacaa 7620 gcgggtggag catatagtgc tgttttaggt attaccgcag acgaaaatgg tattatgaca 7680 gtggggcagg acactcaagc tccttatgtc tctgttactt ttgtatcaga tgacgcagat 7740 ggtaatgagg tatatatggg actgactaaa gttcgctttg ctcaccctga cgttgcgttg 7800 aatacctcag agggtggagg cactgaccct aatactgata ctattgaggg gtctgctatt 7860 agtgactcac gtggatatgt atacgcctct ggtgtgaagt ctgagacgtt gacgcttgag 7920 aaattccaag actttgtagc aaacaaaaca acgccagttg gacagtaaag aggggtaata 7980 cccctctttt tttgtgcgct atatgatata atattaatag aacataacat attaggagga 8040 attataatga ttaaattaga actaaaagta aaaggtaaaa aacaaacatt tacagcggag 8100 aaagtaactg tacgaacaat gcgcgagatt ttagcatact acagtaaaat ggaaaaggtt 8160 gaaaaaggtg agttacaaat gaatgagatt gaggttttag atgatatgct aaacttagtt 8220 ctctccattt tctcaaacac aaaacttact tatgatatgt tagtggataa cgtagccttt 8280 gaggacttat taccattagt acagggagtc tttgaacaag tcaacggggg tacagtttca 8340 aaggagaaat aacaggactt gaggaaaaaa cctttgagga acagttagaa acccttgagg 8400 aaacatattc atccctctta gaaagtagct ggcaactctc agagatagag aacgctgact 8460 actttctttt attacaattg tttggtaaag agtctaaaca agaaaaggtg atggatggcg 8520 ctgactttat taagcgtttc ttaagtcctg aggaacttga aaagctagag aaaaaaggag 8580 ctgattaaca catggtgcaa agcggaaaac cagtaggaaa tatgaagttt ggtttaggta 8640 ttgacggaac cgctgaacta ggtaatacac ttgacaaact aacaaaacaa ttcaaacaag 8700 ctgaaagctc catgaaggca aacatcaaag cgtttgacgg tgcctctgat agtgtagagg 8760 cattggaaca aaagtacagc gacttaacag acgttgtaaa aattcaagag aaacgcattg 8820 aggttttaaa caaacgtaga gaggacgcta taaagaaata cggggctgag tctaaacagg 8880 ttcagtctct aagcactcaa atcaataacg ccacagcaaa atacaatggt ttaactagtc 8940 aactagaaaa aacctccaag gaatacattg acgctaagag tggactaaca caactttcta 9000 aagaaatgaa acagaacgaa cgtgagactc aacaacaagt aaaagcacta aaagacgcag 9060 gggactcagc gggcgcactt gaggctaaac aggagggtct aaaacgttca atctccttaa 9120 ctgagaaagc tattgaggca caaaagcgcg ctattgaaat gagttctcag gagttcggtg 9180 aaaactctaa agaagttgag gaggctagaa tctccctatc taaattagag tcacaggcta 9240 aattatcaag taaagctctt aaatcaatgg agaacgctag tgatggactt agtgacatca 9300 aaggtggagc agacgaggct acagatgggg taggtggact attagatggt gtaatgtctc 9360 taaaaggtgg cgcggtaatc ggtgcggtca cctcattagt gggcactttt gcgggtctaa 9420 cagacggaat caatgaatca aaagacgcca tcaataagtt tcaaggtgca ttaggtcttt 9480 cacaagaggg cgcagaaaac tacactcaaa tggctaacga actagttgct gagggtttgg 9540 gtagccttga ggaaatggtt gacgctatga gtagggttga gcaaaacagc cctatccctg 9600 tattcggtga ggacctacag aaccttacac gttacgcggt atcgttttca aagatgtttg 9660 atacagacgt aaatgaaacc ctacgcggtg cgggcgccat tatgaactcg tggggtctag 9720 atagtaagca agcgtttgac ctaatgacgt taggcgcaca aaacggactt aataaatctg 9780 acgaactagc ggataactta gcggagtatg ctcctatttg ggcacaaatg ggatatacag 9840 cagatgaggc atttagtaca atgcttgcgg gtcttgacgg tggagcatat aaccttgata 9900 aggtgaacga cctagtaaaa gaaattggta tctctattgt tgacggacgg ctagatgaca 9960 acatggatat gttttctcag aaaacaagag acgtttttca agcattcaaa gacggcaaag 10020 cgacacaggc tgatgttact caaagtatgc taaacgactt ctcaaaaatg gactctagtt 10080 atgaatcact taacaaagcc tctacagtgt ggagcgcgct aggtgaggac aacagtatga 10140 aaatgattaa agcccttgcg ggggttgaaa acaatttcac tgaggtagag ggtgccattg 10200 atggggttgt cgattcagca ggcaacacta cgggttggga cgcatttagt agttctattt 10260 cagcattaaa aaatgaagta ggcatgcaac tgctccctat catgagcaca atggctgata 10320 ctattgaaaa ctttacaaaa gacatcttac caaaagtagg gcaatattta ggtgaggtgt 10380 ttggtaagtt acaaccaata ctggaaccgg ttggcgatta tattaaaacc atcacggagt 10440 tattatggaa tatgggcgcc atcatgtttg aaaaggttta tccattatta aaacccatac 10500 tagacacgat ttttagtgcg ttcggtagca ttttcaaaca ggtaagcgag ttctataatc 10560 agtatggtaa acaaatcatg gaagcgttca tgaacttcct taattttatt agtccactac 10620 taaaaattgt aattggttta gttggtgact ttgtcaacaa tgttatcggg ttcattcaag 10680 gtatggttga cactgttatg ggtattataa aaatattcac tggactattc acaggtgatt 10740 ttaaactcat gtgggatggt gtcaaacaac tattctcagg agcaatcaag gctatctgga 10800 actggttaca aattctattc tttgctaaaa tcataaaagg agtcaaagga cttgcctctg 10860 gttttggtaa tacaatcagt ggtatgtgga caagtgtcaa aaactttttc actacaggaa 10920 caagtaacgc atggaacctt gtaaaaggtt gggcgtcaaa cattggaaaa ggcgtttcag 10980 gtatcaaaga caacttcata cgtgttatag gtaacttgtg ggacggtgta aaacgtactt 11040 ttagcggtgg tatggacaca gttgtcaatt ggataaaagg actgcctaag aaactagggg 11100 acggaattaa aggaggcgct cacttcctaa aagacgcatt caaaggtatg tttaacggag 11160 ccttgaaagt aattgaaaaa ccagtgaacg gaattattgg cggtgcaaac tgggttttag 11220 aaaaactagg catggacaag ttaaaaacat gggaggcacc tgaatacgcc aaaggtacac 11280 caagtggcgg tcaccctgta gatggtccca tgactgtcaa tgatggacgt ggtgctgaaa 11340 tggttattga cccaagtggt caagcggtta tccctaaagg taagaacgta acgatgtggg 11400 gacgaaaagg aacccacgtt ttaacagcag aagaaactgc acaagtgtta ggtcataaac 11460 gtcctaagtt tgcatacaaa aaaggtactg gcttctttga caaaattaca ggaggcgtaa 11520 aaaacatctg gaacggtgcc aaaaacatgg ctaaaagtgc gtttgataag gttagcagtg 11580 ttgttggtga cgtttgggac tacgcaacta acccaagcaa attagttgaa aaagtattct 11640 ctagcgtagt agacacctca ggtctcataa aatatcctct agacgttgcc cgtggaatga 11700 ttaagaaagc tactagcgct cttacgtcac gtgttactga ggcgtttgag agcgggagcc 11760 tagatacgtc tgtaggtaca gcgggtgtgt ataaatacct tactaatgta gcgcgtaagg 11820 tgattgccaa ataccctggt atgcgcgtaa caagtggata tagaccagga gacccatata 11880 gtcacggttc aagaaacgct attgacgtag catttcctgc aagcatgaac gggtcaagta 11940 aataccgtca agcgggtaac tatgcttttg ataactttaa atcacaagtt ggctacgtta 12000 ttgctctgaa taaagtacgt gaccgcgtgg gcacatctgg aacgggtatt catgacacat 12060 ggactaattg ggcgtcaggt ggacacatgg accacttaca cattaatggt gtgaaagacc 12120 ctcagtcaca aggtggagca attgacacca cagcaacagg gtcaggggta gaccgttggc 12180 gtgcaactgc taaacgagcc ttacagatga caggacaatg gacaaccgca aacctaaacg 12240 cgctgatgaa ccaaatgcgt acagagtcca atggtaaccc caaagctatc aacctatggg 12300 acattaatgc tcagaatggt attccgtcaa aaggtctaat gcaggtgatt gaccctacat 12360 tcagacaata tgcaatgaaa ccatacaata aaaacattta tgacccatta tcaaacattt 12420 tagcgtcaat tagatatact ttagcccgtt acggttctct aacgcgcgga tggcgcggta 12480 ctggttatgc taacggtgga ctcatcacac gagaacattt agctatggtg ggagagggta 12540 ataaacctga aatggttatt ccactagaca aagccaaacg ctcacgcgct atgtatctac 12600 tagctgaggc acaaaagcgg ttaggtgtat cacaaacaac cgtggtagct ggtcagggtt 12660 ctaatgatga gctaattgct caattgattg tacagcaaca acaaacaaac gcactgttac 12720 aagcattact agaaaaggac acggacgtct acttagacaa acgtaaagtt actgcggaac 12780 taaaccctgc tttaactaaa gataagcaac gcggacaaat ggtatctaac agacgtcaag 12840 ggcgtttagc ataacctaag gaggcttaag cctccttttt tgtgttataa tgattagaga 12900 tagaaaggag aatgattcaa tgaaaattga aaaacaaatg cgctcaggtt taccacaagt 12960 aggggtaaga ccgtatggac aaattcacgt acacagtacg gggaattcat catctacagc 13020 gcaaaacgag gcagactatc atatgcgcag acccgtcaac agtgggttct tctcgcacgt 13080 agtaggtaac gggcgagtaa ttcaaacagc acgcacaaac gcgggctttt atgacgtagg 13140 tggcggatgg aactcgtggg gatatgcggc aattgaattg attgaatcgc acaaaaccaa 13200 agaagagttt atgaaagact ataagctact agtagaatta attcgtctat tatgtgatga 13260 agcgggacta cctaagacgc tagaccaagg gaatacaggt gtcatttctc acgcatatgc 13320 aacggcacat caaccaaaca atggttctga ccatattgac ccctatccat acttgcgtaa 13380 atggggaatt agtaaagagc agtttgctaa agacattaaa aatgggtttg gtggaaatag 13440 ttccaatact gacaacaaac ctaaaccaaa accacaaccg tctaaaccaa aaatcacaga 13500 cacacgtgat ttccctgtag gtagtaaagt aaaagtacgc gccaaagcaa ctaaatacca 13560 aacgggtcaa ccagtgccaa actttgtaaa aggtaaaaca tacaaagtaa aagaacgtaa 13620 aacagttaat caatctgtaa gtaaatatgc gtttcttgtt gatggtatta actcatggtt 13680 cttagcacaa gacctagaca cggcgtcatc taacatgggt aatagctcta aaccgtcagg 13740 agtccttaaa tggacaactg aaaatgctaa ggctactact aaaggcgtca tgaacgttcg 13800 tgcaagcgcg tcaacaaatg caaaaatcac aggtcaatta cctaaaggat atacgattaa 13860 atacaacgca tgggcttatg atgggcgcta tacatgggta cgctatcagg cagataaagg 13920 tacacgctac atggctgtac gtgaccataa aacgggtgaa gtatttgtaa catttagcta 13980 aacgaaaaga gaggtttata cctctctttt ttagtatact ttcatattta cgttgtattt 14040 acttaagtct acattttcat gagtattgta ggtcttattt ttccaatatg ttaccacaga 14100 ctttttaagt aaactaaata caatacaata attgtattcg tctgtataag cttttgtgct 14160 acgtaacaca actctcttgt ctatcatata ggcgccatca aaaacttgct tgtactcaat 14220 aacttcataa tgactaagaa catccattat aatactatta tctactttac ccaaacgttt 14280 actcatacgt tctttacaat gataactagt cctaattgtc tctttacaca ttcctcttgt 14340 agcgctctca accatattca caacagttac aatctcttgt gggttcatct gcttaatgtg 14400 ttttttcaac tcttttctca ttatgaagtt cctccctata ctgattatac taataatata 14460 atatattaaa tttattttgt caatgactgt catcaacttt tttaattaga attatgttat 14520 aatagaatga gaacattatg aggaggttat aagatggcac agcctgtctt tttacgaaac 14580 tttacattaa atggtgtaga tattggtgag ttatttgtgg taggtactgt aacaattcca 14640 ttcctaaatg tagaacgcgg atattatcaa gtgggtaatt cagacggtca gaacctacaa 14700 tatacaagaa taggcaataa cacgcttact tttgatggac acttgattac agaacactca 14760 ggactttcta ttagtgagac aaaagattta ctagttgcac aagtaatgag tagggaacct 14820 atgaaactag tgtttgacgc attacctgat agatatttta acgtagtgtt tgagggcacg 14880 caagagtatg acgcaactaa tttagacatt acaccgttga cgttaacatt ttcatgccct 14940 gagggtgtgg cacactctat tttaagtgac ccatttagaa acacacaaag tacatctaca 15000 aacatgctag tagatagtga atttcaaact aaaacatatt ggtctgatac tactactgta 15060 ttggaaacgc agagaaacgg ttctaatgta ttgtcattag acttttcaga tgaacaaatt 15120 gaggacatgg gtctagtggt tcatgatttt gtttcagatg atgtctttta tgaaacagat 15180 gacctaaccc aaggctcaca agtaacgttt gcaactaact acggtatacc aaaggttagt 15240 gagtttgatg atgatggttc tagtaccttt gaggttgtta ttgatgaaat ggataagata 15300 aacggtaaag tattgcatac acatactaca cctttaccaa ccaatgggga ggtacgtacc 15360 gcatacgctt tcaacgaaac aggaacagac cgtttctcat tcaatgacga acctaaccca 15420 aatataatac ctagtgggca atctgaacaa ccaacactag tgtctgacgg aactagtgaa 15480 tttacacgaa caacaggggt ttctgtacca gaatggggtg ctagtaatgc tgtcaattat 15540 aaggtaacta agaacacaag taataatctc ataggtgtgt tagaaattaa aggaacacag 15600 tacatcatag gacaaaacta cacgcatagt atatatgtaa aaaacaacgg tgataaacct 15660 atttctattt caaacagaat gggagtgggt aaaacaatat atcccaatga gagtaagtac 15720 attagctttg aaccaactta caccatgggt tcaacagata tggggtttaa tttctactct 15780 gacgcaacag gggacttacc tgatattaca atttggcgcg ctaaaattga ggcaactaat 15840 gagggtgcta cacagtggac agacggtaat acacctacag tagacaatac tagccctaca 15900 tatgtagggt atagtaccac ggacactgta cctgaggaca ctgcgccaaa tatcctatta 15960 aacggttcac aggacaatag tatacagtat tggggaatct ttgacgcagt aacggctaca 16020 ccaacagcag gagccactaa attaactaaa acagcagtgt caacaatacg tcctgcatac 16080 ctatcaaatg gctacagtgc tttgcgcggt acaacgtaca ctgtatcagg gagtgtattc 16140 atctctaagg ggtggactgg tagtctagca acaacagaat taattgtgcg tgttacctac 16200 tatgatagta cgcgcgaaga tggaaaagtc tcaatcacaa acacaagtac agacaactgg 16260 gtgcggtatt ctgctagtat aactacccaa aataaagcaa tcaataagat agaagtgctg 16320 tttgttatag acccttcgtt tgtaggtacg ttttacgtaa aaaactttaa actagaacaa 16380 aatgaccatg ctaccccgtt catccaacac attacagaac gtggtaaact atatacgtgg 16440 tattcaattg gcacaggact agacgcgtct acaattccaa tgactcgcac cacgcaaaca 16500 tataccattc aaaatgaagc tactaaagtt ctcagattga gcctaaatgt atatggtaat 16560 gcacacgttg ttattaacag accaatgcta acacgtggca cagatgggac atacgtggct 16620 tctgttaagg agtttctaaa gactgtacct gttaccaatt atggaacgtg gaaaagttac 16680 ccaatctttg aaatcaccaa cgcagaagaa aacggtatga ttgctgttat gaacgaaaac 16740 ggtaaagtcc tacagtttgg caatgaagaa aacaaagacg ctacagagcc aattaaagac 16800 gaaattggtc taaatgaaaa ctacagaggt acgaaattgc caactggttt caccgtcaat 16860 agtgggcacg tatcacagta cccaaatacg tctaacgacc ctgctagacc aaacctctac 16920 atgggttcat gggactacag cccttctgag gcgtttaaac ctaagtgggc tacaacattc 16980 gcaccaaacg catggtcagg accttccctt acaacgcctg tcaaagcacc atcaacaggt 17040 ttacgaacag gagcctttaa atttgaggaa cggatagact tcggtactac gtcagaaaag 17100 aacggacgtt atgagttggt tattttgaca gacgctaatg acatattaat gtctatagcc 17160 atccgtgact ctgacgcaaa aggcaatgaa gtgattgttg aatactggta cggtaacaag 17220 ttactaaaat ctatcaagac agacgtaact aagtacaaat catcttggtt ccgctgtaca 17280 atgacacgtg accaaacggg taagaagttc acttggaact ttgagcatat ccaatcaaac 17340 aacggaatta aaccagttac aaaaaaccca tttacctaca atgcacctgt agcaaacaaa 17400 gcttccgttg ttaaaacatc tagatggcta ctcaagtata aagactcagt agccacaagg 17460 gaggtagtgg ataaggtaac atggacaatg aaatctaagg aagtcctaca cattcgtgca 17520 ggttccaaga ctagttacaa gtcatacggt ctgttaccta agggcgtcac gtttgaaaca 17580 accaaacgtc aaacgggtca aaagattatt aaaaacaacc aatggtatta tgtaactaag 17640 aactcaggta agaaaatacc tgcctcagga tgggtcagtg gatattacct acaaaacact 17700 aaacgtgtgg aacacaagaa gaaagagacc tactctattg ttgcaaaaat gcaggtgaca 17760 gattcaagat tcacatggat gggaacaggt aaatctaaag aaagtaaaaa cccatttaaa 17820 gcaggggaca agattgtcat aaacacacat gataaaacct tctttgtaaa tggtgtagaa 17880 cgtgaggacc tagcaaccat aggaaatcag tgggaaggct tcgcacttga tgtaggagaa 17940 catttcctac agttcattaa ctcagattgg gctacagaca ctttagaagt aactgtgaag 18000 aaccaacgaa cctacttgta ataacatcta gccactcgcc aaagagtggc ttttttatgg 18060 tataattaat aaagaaacaa gtgtaagggg ggtttttaaa atagaatttt attttactga 18120 tagggaattt aaccctatag gaattgcgtc cacagatgga gcaggactca ttaaaatgtc 18180 agatgaccat gagataatca actatgaaac agatgacatt atagagttca caggggtatt 18240 acattttgat gaatcacaag agcagttagt taaagttaaa gaaatggcgc agttgggtaa 18300 ttatctaatt tatagacgac ataacggaga tagtgcctgt cttactatca tggacttcac 18360 acacaaccca ttggcgggaa cacgtgagat aagttgtgaa gatggtgcac ttgacttact 18420 taataatgtt gtacctgcta ttaaaaccac gtcacctcaa tcgtttcaat actactggaa 18480 cattgtcatg agagacacgg gctttacatt gggcgcaaac tactttagta atcagacacg 18540 tactttaaac tatgataatg agacaacagc agtggagcgt ctaaggagta ttatttcaga 18600 ctttggaggc gctaagttta ccattgactt tgagtttgaa aacatgcagt taaaaagtaa 18660 aacaatgaac attgtagagg atatggggga cgagaaagat attactctac gtgttgggcg 18720 tgacgtagat tcaatcgtaa ctacaggtaa catttatgag ttaactacag caatacgagc 18780 attaggtggt acaccagagg ggtcaaacaa ccccattaca ttaagtgggt tctcgtgggt 18840 tgacccagat gggcgtttta aacttgagaa tggggttatg attgacacgc aagaagctcc 18900 taaatggtcc agactcttat caacaacagg aggtttgttc acacgtgctg taacgtatga 18960 cacccttgat aaaggtaaat tggcttcact tgctgttagt gaattgaaaa agaaaagtca 19020 acctgctttt aattatgaag taaacgtagt caatgtacct tctgatttaa atgtaggcga 19080 taggataaac attgtagatg aaaaagatga attgtatcta tcaggtaaag ctctaacaat 19140 tgaccgctgt agcgcagacg ataccgtcac attaacatta ggtgattttc gtattcaata 19200 ttcaggtatt gaccctcagt tgctacagat agcgtcagat ttttcaaaac agtttgacaa 19260 cagtattccg tctgaggtaa ttattacacc gtctaaacag ttttttgtaa atggtgaggg 19320 tacaatcagt atatcagcta aagttgtcaa aggcaaggat gacattactg ataattttac 19380 ttcgtttgta tggcgtagat atgacgcctc aaacgtatta gacacatcat ggacagcaac 19440 aggaaaaaca atcacagtaa atgcaggaca atcaaatgta tatacatatt attgttctgt 19500 agattattag aggaggtaaa aaacatggca ttagagtcaa agccattgag tattgcaaac 19560 gtacaggatg gtcaaaatcc atttttacac acagcttacg catggagtag tgatggaaaa 19620 gagaggttca cactccaata cccaaatgat aatttagtat tgaattatga tttctcgaaa 19680 gaccccacta ttaatggttg gacaggaaat ggtgcgacta tagaatattc aaacgggaac 19740 atgcgagtgt tgtttaacga ctcatcaact aacagaagag tctattatag caatgactta 19800 ttaaccaact acttgccagc aggagttaaa tattccgtca caatagacgc attcagcaac 19860 aataatgggt taattagggt aggtaatttt gacgctctca gtaca 19905 <210> 70 <211> 5499 <212> DNA <213> Artificial Sequence <400> 70 gggggtattt tttagagcgt ctaaaatatt tctaaggtaa ttatacccag aacacttaga 60 acgtatctca gagcctctca gagcgtttta gagcatgttt gtttttgagc gtaaaaaaga 120 gagggttatt tccctctcaa tttgtttcta ttactgtttg gatgttcttg tttgttgtga 180 caagaaaaac aaatactttc taaataattc atatctaacc tatgttccca tccctcagag 240 gttcgtatct ccgtggtatg gtgcaccatg tctgctttgg tagtgatatc tttgctcata 300 catacttcac agaatggtgt ctctaatagt tttgctttac gtgttgctct ccattcaggt 360 gtgtgataga acatattgta tttactattt ggcttactat atcttactct cctattgtat 420 tccttaccgt tgtctccttt gtgtatgtca cagtacattg ttcctacagg taccttgttc 480 ctacaatagg acacattaca tttcttcatt ggcataacta cactacctcc atccattgtt 540 gtatcatggt atcactaata gatacaccat tggttatact gtcatatacc ttttgttcta 600 tctcattatc agctaacagg tagtagtaca cagggtcact ggtagatgtg tgccgtgcta 660 tccgtccctt catttgttgg tacgtaatac tagaaagggg tagctcgtag aataccatta 720 tgtgggatgt agctaagaag tttacccctg tacttcctgc cttgaattgt actagaataa 780 tcgcgtcctc atgttgttcc catgtctcta agtccttaat agagccatta tatattgaga 840 taggtctatc acctttagac aattcctcta ctaatctatt acacgtttct ttatattgat 900 agccaataac aacgcgttct cctttagttt cttctagtat gtcttttaga cggtctgtct 960 tgctgttttt agctacttta cttacatatg gtataaaacc attagacgca accctaagtg 1020 cgttaaacag cttgctaggg ttatctaatt caattatgtc acctgagtct gtttcatata 1080 ctctatgtgt gcgtagtttc ttaaccattg atggtgactt gactttatac acaatatctg 1140 atgggatgag tttgttgtca cgtttaatag caacgctgtg ttctttgagt agctcattta 1200 attcctcagt gtttctatat cccacaatcg cattataaga ccgtccacct aaatactgtt 1260 tctcttctat acagtagcgt tctctaaaag atttccacgt tccagagtat aaacctgcga 1320 ttttcaattg agaaaaccat tgttctaaca ttccgttaga aattggagtt ccgctcatta 1380 aataggtgtg tcctgctttc ttacttactt tcatccaaaa cttagttacg tttgcgctcc 1440 tgtttgctag acagtgagac tcatcaaaaa caatcatagt gtctttatct ataaatttca 1500 ataattcagg tgttcgccat gatgattgaa agctgattga tacatattgc gttcctgacg 1560 cctctagaag ctctcctctg agctttggag acccacttag ggtaattata cctaaacctt 1620 gtttagaccc ctcagaagcc caatcagaca ccttagacgc aaggcacact actacgagtt 1680 tctttagccc tgatttttta aacgattcta atgccatgag tgtcttgcct gagccaacct 1740 cactatgatt tagattatgt gtttcccatt tgtctatgac catttgctgt tgttccgttg 1800 gtattaacat tatattacct cctccacatt agtctatcat gaaaccatgt agggttgttg 1860 tgttgggtag taggttatat tttgttatta ttgtacacat tcaaaaaccg tgtacacttt 1920 ttgtacaaac ctgttttacg ccttgtgtat caatgtttca accctgtttt aaccattgta 1980 gtgttgtggg atgacctcag ctcttataga aaacaattac attttccacc taccataaac 2040 accattatat cagtttttgt atatattata tattgtattt atttttttct ttatataaag 2100 taataaaaaa taataaagaa taaaagaaca taagtaaacc ccacgacaca cgtggtattt 2160 aaccgtacca aaaaaatggt acaatcgtgt acatttgtac caaaaatgtc tcaaaccctt 2220 gtcccccaac gcttaaaaaa ccgtacacca ccctttgtta ttttattatt tttgttattt 2280 aattattatc atcaaaatgt accccaacaa ggtgtcccca tcaagttacc ccttgcgctg 2340 acgtaaaaag tatgctaaca taataaacga agaacgaaag gagaaaacag gcatgatgat 2400 tcctacaata cacacagaaa tgacaccaga agtaaaagac atttatccat taacctattg 2460 tcgcgataag gtggacctac ctatagacat tgagtacacg aacagaggtt cgcgctttgt 2520 cgttggtgat attgattata ttgcacagac aattttaaat aatactaccc tcatcttatc 2580 cacagatggt aagagtgcat gggtattgaa caaagatacg aacatttggc actatgtttc 2640 taataatgta cgtgaatttc tactatactc tgtcatttac ccacaagcgc aagagtttaa 2700 aagtggtgat agtgataata aagtaggtac gttcttaggt aaagttgggg acaaggtata 2760 cgaacttgtc aaaggtaacc ctcaatttaa agagggatat ttcaacgata gaacgaacga 2820 taagtacaga taccttggtg aatgtgcgta ttttcaaaac ggtgcgctaa acatgcgtac 2880 attagaacta cgtccgtttg aaccatggga ctatagaacg caagacacca ttttacccat 2940 tcatgtaaaa gagacacctg tgacgctacc agagattgag aaaaatagac tatggcaagc 3000 ggtcaacttc tttactgacc cactaagtga aaaagcatta tgtgagttca tagggtcatg 3060 cgtctatgag aacaaacctg aggctgttca tgctcaaatt gttgtctcac gcggtacacg 3120 caacggagga aatggaaagt ctattctaat gaccaaaatc ataggctcac cattgtttgg 3180 aaaaatgtac acagaactcc catctaaccg cgcatttaac acaaaaggtg agtttaatag 3240 tgcgttacta gttgacaaac agttgatttt cattgatgaa ttgaaccctt ataatttaga 3300 accagaggta tttaaacaac aaattacggc tacacgcatt aaggtgaatg aaaagggtaa 3360 ggctgaatat gacgcgcgct ttggcggaca ctttgcgggt gctagtaatg atgtatttaa 3420 agtacgtgac gcctcagatg gttcgttaag acgtattttg ccaattattt tcaataagca 3480 agtgacaaaa ggtgatgaca aagtaacgtt tatgcgtcaa tttaaccctg atgtgtctac 3540 tgagatgaga gacgcactaa acaacgaaca tgagaaagct gagtttatta gatggtgtgt 3600 acaggagtat gctgaactat tgaaacgcag agaggacgtt accgcagacg agtttgtgtg 3660 gacgctatct gatgaggcta aggaaatgcg tgaggaacta gtacgtagta aaacacctgt 3720 tattgattta gcctttaata gtggactatt tgagcacacg ggtaatgagg gtgaccttgt 3780 tgaattgaaa ctcttcacgg acggtattct tctagcaaac agatacaaca cagatgatag 3840 aagtagaata acgcgtaaaa tggtaaaaga ggacatgagg gactatatgt acaatgaggg 3900 taaacgttcg cgtattaagg caatatgcac gaaccctaag caacaccacg tagatgactt 3960 gaatactgta gcgggtccac gtgtgtacgt gagtgggttt aagcttgcac atgatgacct 4020 tgacagtgat ttagaaaaga attggtttga gacgattaag aagcatttag gcaaacacac 4080 gattatggaa gaggtttttg acgtttactt acaacctgag gaggtatttt aaaggaggaa 4140 taaagatgtt aggttgtgat tattgtaaat ttgaaccaat gagggagaca ctattttcct 4200 cagattactt atggagtggg aggactgaca tgactgaggt gtttataaac gggaaaacta 4260 tgacagtcac aactgaggtt gacaaccaag gttataccgc tcagtttgag attcactatt 4320 gcccaatgtg cggtggtaag ctgattggag gaggtttttg acgtttactt acaacctgag 4380 gaggtatttt aatgtttaag gttgaacatg ttagattaac agaatataat gacgcctata 4440 tgagtgtact gttgtttagg cagaaagtac gtagatatta tttaactgta aacggtaagg 4500 agtcaagaga gtataaatac cacttgtggt ttttgcaaaa agtaccacta ttgtataaaa 4560 ttagtaggta tgtaaatact cgtatagcaa taaaacgcat tgaaaacatg gggggagaac 4620 gaaatgggct actttaagaa tttgttatta gcgttgggtt atattgttgc tttgtttacc 4680 ataattaagt tgggtgcagt tggttttggc tatttaatga cattagtgag ccatttgtca 4740 ggtttagtac atactctagt gtgctttatt agtaacacac ttgattctga accgcttaca 4800 ggtgtgtttc tagcctgtat tagtgcttca cctctaattg cattgtgtat gtggcttgat 4860 gataaataga atattctcat taaactctaa tggtttttta attgactatt agagtttaat 4920 tgtttatact aggttcataa ggttgagggt taagcctacg gggtgaacga gtaccaacca 4980 ataaagacaa gggatggtta attatgatta aggtgatgaa ttgggagtat gaatatggaa 5040 tgaaacgagt agcattctac aaagaaattg gtcatgagat tgagctttta gatagagaaa 5100 aatgtataca cttttataga gacggacgtt attatgctac aattgacaaa aaaggtttta 5160 gtggtggtta tcaccttaaa caaacactaa attaggggag gaatttaaat gaacacatat 5220 acagtttatt accgtaacat tgatgagcac tattgctgta gtattcacgt tgacgcatat 5280 actattgaac aagctattaa taaagggtta cagtaccttg aatatgaaga acatttagac 5340 tactcagaaa ttgagatttg tcacgttgag aaagtggggt aaatgaaatg acaccagaaa 5400 acgttgaaaa agagtacggt gtgtacgttg ttggaggaga cattattgat atattagacc 5460 atgtttttcc aagctatgaa gaagctttag aacatgcta 5499 <210> 71 <211> 5324 <212> DNA <213> Artificial Sequence <400> 71 cctgttacat atgagtcatc acctttaata taggttactt cttctgtttc aagttctccg 60 tcctcatttt caactggttc aagtttaccg gtttttactt tgaataagtt aacagcttta 120 tcacccgttt tcacagcaaa cacacggttt actttctgtg cgtcatgttc attaccatca 180 ctatcaacgt atacagtctt gtcaaacgtc caacctgttt tagtaataat ttgaaattga 240 cgcaggtcat cacattcagc aatatattgt ttgtaatcta caccgctaac aacgtagttc 300 agaaacgcat tagagacaac tgcttttgag tattttaacc cacctgtaag cattattcca 360 ccgcgcacct ttactttacc tttagcgtca ataccaatat aattgttgac atctttctgg 420 tataaggcaa tgaactcatc tttgtccaat acaataccta cgcgctcaga aatgtcatca 480 cagaacgcgt ctgtaatacg ttcagcctcc tcatcatgag gaatgtaggc gtgacagtct 540 gtgttgctct gtaacatggt aacatggtcc ctaattccct cgtagaagtc agccataatt 600 aattgcccaa tcacacatgt tagaaattga aaacgtgggt catataaccc attaaactct 660 gcacctgtgg caccaaacaa tgtattaata ggcaatttta ccccatttac taacacatac 720 attggtaacg ttacttcgtt cattgtaatc tctgtttcat ctgtatattt agcctctaga 780 cgtttatcta agagttcttt cactaggtgc ttattctcct caggtacgtt acgagaaaga 840 acatcaaaat tcacatacac attagggtac aaactaccgt agtcacgcat gagaaagcgt 900 ccaatgtgaa taagctgttc aacagctccg tggacacctc ccgcgccaaa ctccataaca 960 taaccagtat tagggtcagt atacgttcct ttagctacgg gcttaccttt tttatttagg 1020 tcaaactcat ggtctaaaaa catttctcta atctctggta tagttacatg aatgttttca 1080 ggtaatgtaa atggttcagt aaggtcatca cgtacactat taggacggtt ggcacccatt 1140 aattgagcta ctaaattagc gtttgtttgg ttaaatgctt gtttatcaag gttgaacatg 1200 gcacaaataa acgctttagc aagtaaccca tcaacacaac catagaagcg tagctcagtg 1260 gcgtctacgt ctttccaaca ataagcaacc tctttgcgta gttcctcatc tgttagttta 1320 ccgccttgtt caaagtcaac atccgtctct ttgacttcta accccatgaa accctcatgt 1380 tctttcagtg aaaacccttt gtgttcatgg tacaggtcac aacctagaat aggagttttc 1440 ttcgtgttaa agagtttata aataagtcct ctatcatctg acttaataac agcctgtgac 1500 aactgaaacg cgtctttacc ttgtaaataa ccacggagca cattattatc ataactagca 1560 gagttataac cagtaaatag actgtcacgt acttctaaat accatttacg cgccttgtct 1620 aggtcattga caatttccca acgtttacca ctaaacaaat ctttagcaca aatgacaaaa 1680 tcttgctcaa atacctcaat atcataaatt actaaatatt gtttcccgct tggtttattg 1740 ggacgcggtg gaacttcatc aaccttgcct gcaatttcag gcttacctaa attatagaac 1800 ccatctttta actcaatgtc taccctcacc actgatagtg gctcaatgtc ctcccaacgt 1860 gtaaaatcag gtttccaatt cattaagtaa gaaacagcct ccctacctgt gcgtgtctca 1920 cggagtttca ggcgtctcat tgggttacct tttttagatt gtgtttcaat gttctctgta 1980 acaacaacct cttttattcc ccctgtcatg gggtcataac tcatggcgtt accttctaat 2040 gttttccaaa gttcaaacat ggtacgcgcg ttctcttttt gttgcttagt tggtgtgaaa 2100 atagtgttca ttaatttcat ccccctcgtt cactagtata taataaaacc ctcgcttatg 2160 caagggttaa ttttgtgaga catccataat gtcaacagac tgtaaaacta atgtgtcaac 2220 tggtagcaac ttatcaaact ggttacctaa ttgttcccac atttccataa ctgtaaccca 2280 tccgtcacca ctaccattat aaccgttgct agggtcattc atgtcaacaa gaacccatcc 2340 acccattaaa ttagatggta ggaaaaaccc accatattcg cgtacccata ttgaatggag 2400 taagttatct tctgtaggta tagttttctt agtcatattt acaagtttca taagcagtta 2460 cctcctataa ttcctctcta gccttttcaa taaactcgtc tatactaaca taaccaagtt 2520 ttagaagttg tgccacctgt agcattgcat agttagcata taatgtgagt gttcggtcat 2580 caacaccttg ctcacgcatg tcgttttcta aatcaattaa aatacggtct gtgttttcaa 2640 cttctactaa taactcatag ttattcatct tcgttttcct cctcatctaa catactaagt 2700 tcttcgcgta agaacttgac aaccccttct aatagctcaa ttgtttcctc tttgtttagg 2760 ttctcacctt ccccctctat tgctcccgtt gccttacctg tgttcatgtc tacagccaaa 2820 ataagtaaat cagtatgaat gttcattatt tttcctcctc aaatttaatt agcgtatcta 2880 aatacacacg tgccttttca aggtcagtaa tgccaccttt ttctttgtgg cgtttaatgt 2940 acttataaat gttaccaatt aagaaaccct catattggtc atctgttagt aggtcatctg 3000 ctaagacgtc aaacaattgt ttacctgaat tggttgaata acgtgctgta tctgtcagtt 3060 cttcattcac catattagcc tgtggcttat cagtttctag cacattttta ataaaagtgt 3120 aattatcatc taagtactct tcattataaa ggttatcatt atcacctact gtaccccacc 3180 agtagccctg cttagtgtct aattgaatag tcttaccttt gaaaacatct tcacccccta 3240 catatgttaa aatgtcaccc tttttgtatt gacgtcccat actattcctc ctatgaaaat 3300 aagtgtctgc gcgttgttag tgctgtaata atgtcaatcc atgaaataac cactggtaca 3360 cccgtccaaa ataagaatag gaacaagaaa cctgagccaa gttttccctc atacatacgg 3420 tgtaagccaa tgcctccaaa caacaaagca ataataacat atagtcctaa acttggttta 3480 ttcattctag tagtcctcca ttaatgtttg tatgaaatcg tttaactcgt ccacgtagtc 3540 gtatagagaa tcaaggtcat caattaattt atcatttttc tcaatgagtt catcaacttc 3600 cttatctaaa aattcaacct gaccacgtag gttattattt agctgactaa gttctgcgtt 3660 ttcctcaata agctcctcat tgtcctcaat tagttcagct atgcgttgac ttttatggtc 3720 aacctcatct gctaactcgt ctacctctaa acgagcgtct aacaactttt cccttagcat 3780 ttcgttttct ctaatgaggt tattacgttc acgaagtaat agaactttat cctctttatc 3840 aaggttctca ggcgtttccc atctattgga cattaggttc actctcctta taagtgaaat 3900 cacttgcgaa aaatgaagcg taacgtttat cattaatgtc tgtagggaat acccaagtta 3960 aatcactagc ctcaatgtaa atgctatctg tttctaagtc aagcaatgcc tcacgtccaa 4020 tgagtaactc ctccttacct acaggcggtt ctactgtacc tgtaacaata acaggtgtca 4080 cttttgcttt tcgccattta ttaatcgtta cagtaatcat ttatttttcc tccttattag 4140 acattattcc cataggaaca tatcatttct tataacaaaa atatcttctg acttagtatc 4200 ataatgcaac tctacattat gatactcttt catataggtt tttgcataat caaacaaacg 4260 ctctggacac ttaaaactaa atgagccacc atctgcacat ttacaaatta catgttcttc 4320 tatactacta ttgacaaacc aattcacaca ctctggcgga tagcctagca caattccaag 4380 tgcataatct tctccgtgtt ttcttgacaa tttagaaaac tcatccaatt gctctaactt 4440 ggagacaaca agcatgccac tatatacgta agttgtgaag tgttccctta caatatttgt 4500 aagttctgac accctaataa agatggcgtc tctcagtccc aaattaaatg ccacagtttc 4560 ttctagtaaa atattcatgg tgacctctcc tctttacccc tcatgtctct cattaacaac 4620 ataatcaaag tcacttgcaa atagcggaat cattagttct ccatcaacgt cacagtgcaa 4680 tagaggtgta cggtattggt agtcaataaa aatggtgtct gtttccttat ctacatatgc 4740 aaaacaaccc gcgtactcat catatacgtc cgaatattta cctcttaaaa tagttacttc 4800 tagtacatta ttatatgttt ctccgtcaac tataatgttt ttcatctgtt ttcctcctta 4860 gttatcttac atttattatg ttaccactgt ttacaaaaca cgtcaactac ttttttgaaa 4920 tttcttgtaa ttctttagta agacaatatc cctctgtttt tccatctgta cataaatata 4980 attgtgggaa accccacgcg ctccattcac taaaaccaat tacacgcaca accgtaccat 5040 ctttaaagtt acaatcacta tcccacggtg tcacaatgca ctctaaaccc ttttttatca 5100 tagcaccaac ctcacaactt ctataacgcg ttctacaccc tgtaagtgtt cagcaatctc 5160 acacgcctca aaaatatcat tggcaaaaat aagacattcc tcatacttca tacgccaact 5220 aatgtacgtc actctaaaca ttatacatca ctcctgttct aatttctaag acctcaattc 5280 ctaacacttg ttctaaggca acaaactctg tcttatactg gtta 5324 <210> 72 <211> 4977 <212> DNA <213> Artificial Sequence <400> 72 ttaataattt attagccatc ttcgcactcg gtttttctac ctcaatgaag ttactaggtt 60 ctaaataagc tttaccgttg tcagaggtat atacctctaa tgtgtcacct gtgttaggga 120 caccaccaat tttgtttagg tcctcgttaa atcgctctgt aacctcatct tttttagtcc 180 attcttttgt cttactattg tagtcctctt tgtacaatgt taatgtgtac agtttagaat 240 agtcctcagg acacacacta atcactaaac ttttgtcctc gtcctcaact gctacaactg 300 ttaatttttc aggttcttta ctcattaaaa tctccctctc ttatttcata tagtgttatt 360 ataccattta tgtgtaaaac gttgttatac tagctcatac gcaacatcaa ggttacctaa 420 atcattttta gcaatcttaa caataacaaa ctcatcctca acttcatcct gttccccatc 480 cacgcgtata gtcactttct tttctatttc ttgctcctgt aaacgcattc cctcagcgcg 540 tactttctca tattgctgta ctgcctccat taggtctaaa ccgttgtttg catatacagc 600 tagaatagag gttcgttggt tgcgtatagg gtaccacgct ttgagttgcc tgtagtcact 660 gtcaaatcgt tcaaagaatg aggtaaggga ctcatttatt tttgactgag ttacattcac 720 attggctaaa tgtgggtgca tggttttgaa catatcaaac gtaagccacg taggagcctc 780 atagccctct ctaaatcgtt caaaggtaac ttgtacctca tcccatttag aacacctctg 840 agcgtctcta tacgccttta tttgaacatc caaagcgtcc tcaccctctt ttagtattcc 900 tctgagatgt tttatcttat cctctagctc gtcatagggt cgtaaaattt cttttttaac 960 ccgcttgcgt tcgttgtcta tgttgctaaa ctctttgcga gcctgtgcga ggagtttttt 1020 atattccttt atgttgtcct ctgttacctc aacttgtttc atttcgtttg ctaacttggt 1080 aatgtcatca agtagtttat catattgcgc aaactcaata gatggtacat cacctacgta 1140 aatcatcaac tcgttatcca ataattacac cgtcctcatt tactgctaca acctcaccat 1200 atccaccagt taggtcccta accattttag cggttgttat gtccattttt agacgcggtt 1260 tatcagtgac aatctgtcta aaccttgtgc gtcctctttc ctcatcataa atcggtgacc 1320 ttgaggaaaa tgcagtaaaa tacacgtatg aaccatcaaa gtctttgtag cgtactacgt 1380 acttatacat aatcataacc tctttctttg cagtattgta taaactcctt atcatgtctt 1440 tcgtctagcc cattctgcgc cttgaggttc tcatatgagt aataactacc actctggtgt 1500 aaatgaatac tcgtaccacc ctctgacaag tatttagtgg cgaactctgt attttggcga 1560 actgacaaat gtctatagga accattatta tacgtatcat aaccgctgtg aattttcata 1620 tattcactat aaccaattac agcaccgtca tagttagcct ctaggagtaa caaatcaatt 1680 ttcttacctg ttttatcaag gtactcactg aatgccacag tagtcattag gtctgtagcg 1740 tataaaaaac tttgaccgtt tgaggttccg ataatgccta agttttgaac ctcatgagga 1800 gcgtctaaaa acgtacactc tacgccactc acgtcaatag tggtaccgtg ttccactata 1860 atgttaacgg gtgccttacc ttttgaaaca agtaggtcat tgacctcctt acacgctatc 1920 acctttatcc aagggaagtt tttccgtatt tggttataac aaccaacatt caggtggtct 1980 ccatgaatgt gacttataaa aagtaagtga cagtcctgta aatctttttt taatacttta 2040 aatgaaagtc ctatatcaat catcattttt ataccattct gaaatgttaa tttaaccgcg 2100 ttacctactg acccactgct tataatctta tattcaatca tctaatcaca cccaatcata 2160 ctctgtttgt tcttctgaat tgtcgttctc taggttccat aatagtttac ctaatcgttg 2220 cgcctctagt tcctgttcat tatctagagc atgaccaatt ttacagagca gtgtgtggcg 2280 cattagttct aattctttac gcagtggtct attcattgtc tcactggcgt caaacatatt 2340 agaggcatga aataaattgt cataacaatt attcaatgtg tccccatctt taaagcccac 2400 aaatttatca ttacccacat tgggaacaaa catatctgcc accaacttag caacatacat 2460 aacccttaca cactggttac cttgtgagtt acgcgctgtt agacgtacat ataagcgacc 2520 gtttgagtca tctttctgca ttggaacaat catgtcatca tccacattaa taatgtaacc 2580 catgttagaa acgctgtaca tatcaaaagg ctcgtccatg ggttcaaacc gttcatgttt 2640 cgtattaacg tttctcatac tttgtaccac ctttgacagt cgtaagctca gtaattgact 2700 tactttgtgc ctccatgatg gcgactaagt atttgcgctc tacactataa cgcacattta 2760 acatcaatga aattgccaaa ataacaccta gaataattgt acccattata aacacttcct 2820 tttctaatta tattctaata ataccacaga atggagcact tgtaaacaac tttttacatc 2880 cctttttata aaataatatg gtataatatg tgtatactta ttatacattg tttttctccc 2940 taaaaagcac tacacgctga ttcctcccaa cgtgtagtgc tttttattat tttgacgagt 3000 taagttcgtc aattgtgtca ttgtatgcag tagctaggtt attcatgagg tcaccaattt 3060 ttccaattat ttggtctggt tcattacccc ctaaaaggtt acccatatct accgcatcgc 3120 agacgtcaat catctgtgta atagcactct ttacaattcc tgactctaga atgtcaaacc 3180 ccacagcgtg tgcgtgcagt acattgtaag caaacattag acgagcgtgt atcataatgt 3240 ctaattcttt aggctcgtcc ataatgcggg cacgcaattc atctaaaaca ttgtctaact 3300 ccgcgtcatg taattctaat acctctgcta attttgtcat attatttttc ctcctcatag 3360 tctaatacct caatttggtt atcatatacc caccataggt gaccatcaat acttagttca 3420 agttggtgcg tttgtccgtc aatttcttca gcgctatgag ctactctgaa cacctctcca 3480 acgtattccc tgtcacgctc gtaaccctca ttcataaaaa attcagttgg ttcaggttta 3540 atcaagcgca ccttcgtccc cactggtagg ggtttagtaa aattatcctc aaatacttta 3600 ctcattttgt tttcctccct ttatcctaat acatcgtcaa tacggtctga aatcgtgtct 3660 ctatcaaacc catactcatc tacgagttta gcacctaaag cgcttgccat aataatgttg 3720 aaagcaagtt tttcctcatc tactttttta ccgtatttca acttatcaaa atcaaacttt 3780 agttcctgta agacgttctc aaacgctttg tgtgtttctt ctttattcat ctgttttcct 3840 cctaatgttt taatacattt attagtttat caaaacccca accagttgtc aagcattatt 3900 tttaaatttc ttgtaaatgt tcgtacggaa tgagctgacg tataccatca atcgttctac 3960 atggtatagg gtctctgtgt ttctctttct caattaatac tttctctgta ggtgtcaatt 4020 cgttttcagg tagttcgtac aagactgccc caattggtaa aggtgtcgtc tcgttgttta 4080 ctaactcata tgttttcaaa ctaattcctc ctctagttta tcaattatat tctcaacttc 4140 atttaataag tcctcgttat caacattttg ctgtactacg ttaagcgcgt atagtgctaa 4200 ttcagtaggt gagtcaccgt caattaatac agtatcaata acattagtca cagttactaa 4260 agcactgaag acaagtaact cagcagactc aatacccgtt ttctcattta actcacgcgc 4320 cttttcaacc actaaatcac ctaattttgt agtatctaaa ttcatgtcta ttttcctccc 4380 ttatttggtt gaaacaacca tttagaaaac attagtgaca accctataac taatggcgtt 4440 aggtatgcaa tcaattttct gagtcctccc acgctttaat gaacccctca atttctttga 4500 catccccatc caacaaacca cgttgaacta gttctaatct aattttcata tatgccacat 4560 ctgacaagtt ataccatccg tagctttcag cagaacgctg taattcttgt agaacacata 4620 tagccttttc gctatactcc ttatcctctt gttctcgttt tacatactca ataacttgct 4680 tacccgttgc tcctcccata actgcgtaca aacaaagcaa gtctaaatct gttaagtttt 4740 ccatctgttt tcctccttag ttatcttaca tttattatat tatcagacga ttagtcatct 4800 gtcaacacta tttttaaact tctttcaaaa tttttctcaa gtctctaagt tgtgcgtctg 4860 ttaagtgtac gcttactaca tcattcgtaa aatcagtaat tttaatcact gttttatctt 4920 tatataacct agcgacactc aaggtagcac catgtttatc tttcaaacta tattcaa 4977 <210> 73 <211> 3444 <212> DNA <213> Artificial Sequence <400> 73 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactaatg cttttagtat acagggtaat tcaaatgctt taattataac 240 tataacaaaa ataaaaatcg aactaggaaa cacggcaacc atctacaccc caaacccatc 300 tgaagatttc gcgaacgcat atccgctata tatgggtcaa tatagtaact atactcaaga 360 acctagcacg gacccaagta agtacacgtg gatgagaaca acgggacaaa atggcgcctc 420 tgtcaaatca actaaaacag agtgggcaat caatacctca agcgttgatg aacctacatc 480 aggatggagt acaaccatcc caactctaga aaaaggtaaa tacctatgga cacgtacaac 540 gtgggagtac actgatggta caacatcagt agcctataca gtgaactata ttcctgtaga 600 tggctcaacc ggtaatggtg tgaaatctat cgctgttact tacgctgtag gtacctcagg 660 tacaacagca ccatccacag gttggcaagc aacaccacca aatgtaacag gtggtcaata 720 cctatggaca cgtattatct ggacatttac agataatagt aaccaaacaa cctactcagt 780 ggcgcgcttt ggtcaggatg gtattagtgt gactggtact caatcagagt atgtacaaac 840 aactagttct gtagaaccta cctcaggatg gagtacaaca cgtccaacac ctcaaattgg 900 tatgtggttg tgggtaagga gtagaaatac gctttcaaat ggtacgtata caaattgggt 960 agtaactagc tcatacacgg gtagagactc aatttttatt agtgctacag ctccaagtaa 1020 cccaactaca gggacattat ggcaaaaacc taatgaccct actgtgctaa aatggaacgg 1080 tacagcgtgg gaaaactggg ggatgtcaat taataatatt gtatcagaca atgttattgc 1140 tgaaaacggg atgtttaaaa aagttagtgg ggttgagatt gtaggtagta ccatcagaaa 1200 cccttacaat gtgaaatatt cagataactc aactggctca ggtgaaatta cactagagaa 1260 ctcacaaatc aaaaacaata taaaacagta cagtagcaca ggagtgttta aaaacgcaca 1320 tcgtcaaatt atggcagcaa actatatact catggctaca actaatgaag caggtaacac 1380 aaactacaat caattatatc tagaccctga cgcactaaat ctacaaacat tcagttccaa 1440 cccaaactct ggtggcaatg gctacggtgc agagtatagt agtacaggtt tgcgtctaac 1500 agattcgcgc gtttcattag gtaactcaaa gctggaaatt catgatttaa ttaaagttga 1560 aacaaccatg ttggaccctg cgtcaggttg gcaaagatat agtgatgtta tgggatacac 1620 taacacacct acagccacgc gagtaggtag aacggttcaa atagcaggtg cgtttaaacc 1680 cataaaccaa cttagcgcag gtcaatatgt cattaaccaa cctctaccag tttgggctag 1740 accattgaat aacgtaacac tcattcatca aggttctgga atgaacaggc tactactaga 1800 agtgcgcaag gatggtgcaa ttctagtaag taggtatggt actacagtag atagtgcgat 1860 tccgtcaggc gcatggataa acatctcttg cgtatatgcg ggtcaagatt tattctaagg 1920 gggataatta tgttagagca atttaaaacg gagtatatta acaaggtatt aaacggtaat 1980 gggtttgatg atgagttaaa tatgctgttt aacagagttc tagaggagga gttccatggc 2040 aacgcgttag ccatggacga cctcatttat gaactaaacg gatatagcac tcaagataac 2100 gcagtagaca cgttacagaa ccaagttgac tacatgagta aaatgataaa tagactagca 2160 tacaatcaaa gttaggagcg ggaacgaatg ccaatgaatg aggacaactt tatcaaaatg 2220 caattaacca tggagcgtat tgacgcacgt ttagaggacg tgagagagat taaaaaagag 2280 ctgtctggtg cccgtcaaca aatcgcggac ctagacaaac gtctttcgca gtcaattgac 2340 catgttaaca aactagagga cgacatcaaa gagctagaat cacgtaacac atggcttact 2400 agaacaaccg taggagcaat tatcactggt gtagtgggtg caattttggc attcatcact 2460 ggttaaatat atgatataat agattagaaa ggggaactga catatgaaaa atattaactg 2520 gcgcgtgagg tttagcaagg acaatatctt attctgggta cgattcatca ttggtgtaat 2580 tactcccgct ttagcatact tagcgctaga acctcaggac ctaagcacat ggcaaggttt 2640 aacggacttc ttaatgtctg tggtatctaa cccgtatctt ttagccttga cctttgtcaa 2700 cgcggtaaac ttaattcctg acccaactac gccaaacctg agtgatagtg aactcgttct 2760 aaataaaacc tctgtaaaag agtaaagaga cctatatagg tctctttttt atttaatcaa 2820 ttgtcttagt tcaggtacat taaaacctaa tattaattta ccatctacct cagtgactgg 2880 taccgtcttg aggttcatgt tcattaaata ctcacgtgcc tcaggttgtt cctcaatatt 2940 tacctcatta taatctaact catgttcgtt tagaaacttt ttaaccattc tacattgtgg 3000 acagttgctt tttgaaaaaa ctttaatcat taatcgtaca atctcctttt tgaaatgtgc 3060 ttagaatcgc tctctgagcg ttttagcgta aaaatttaca atattaaacg tattgttttg 3120 gctctggtag tgaaccatac agctcattat attgggcgtg tgcttcattc aaccgttctt 3180 tccaattctc accaaaccat aatactaagg ttctttcaac ttctaactca tagtaattaa 3240 ggtcaatttc atctaattgt acaccttcac caatctgctc attggaaatg gtatagtatt 3300 gaggggggtt gtttagacct gttacatatg agtcatcacc tttaatatag gttacttctt 3360 ctgtttcaag ttctccgtcc tcattttcaa ctggttcaag tttaccggtt tttactttga 3420 ataagttaac agctttatca cccg 3444 <210> 74 <211> 3179 <212> DNA <213> Artificial Sequence <400> 74 gtacttagtt gttttagttg ctttactgat tacagtattg gtttatatac ttatgcgttt 60 gttctaagga gtgatacaat gaaatacaac caatttaagg ggtttcctct caaagcgcgt 120 actaaaattc ccgcgataaa agagtggcaa gctcaagaga gttacaaaac attaggtaaa 180 ataagaaaca tgaataaagg ggtcttatgt ggggaacaaa acaaattatt agtagtagac 240 tgtgacgtaa aaggtaaagc aaacggaata cactctttta ctaccttaat gaaagactta 300 ggacatgaaa ccatacctaa caccctaatg gtctatacac cgtcaggagg catacactat 360 tattttacgt taccagatga cgcactagac ctacgcaaac aacctagaga ggacttaggt 420 atagattttc agatgaatgg gtcctttgtg gtagcagtag ggtcagagtt agaaaacggg 480 acatatagcg tggtttccaa taaaccaatc gcacaagcac ccagagaatt aattaactgg 540 ctaattgaga acgcaaagca acataattac ccaacgaacg caacgccaaa ccaattaaac 600 agaagtctag acgcatggtt taagatgtta gcgtatgaga gtggtaaaat gggtaacgaa 660 ccatggcgcc ttaacggatg ggtatataaa tggaaaaagt tgacaaactt agatatttca 720 actataatag aaagtgttaa aatcgttttt aaatacctat atgggtttga gcctcctgta 780 gaactacaga cgaacaaagc aaggggtaaa gaacactcaa acgcactttc acggttctta 840 gaatcacttg tatatacacg tatagacgag ggaggacgta acaatgcact cgctcagaca 900 gcaggaatgt tagcactggg aacgaacaac ttagacctgt ataaatgggc gtgtaaattg 960 tacatgacaa cctgtttcag tgaacctctt gacgagagtg agtttgaatt aacagtaatg 1020 agtatttgga aacgtgaaaa aggtagatga ttatatgaca cctgttatta atgaaagcaa 1080 tgagacccgt accattacca tctgcatggt caacggacgc tcttacacat ataagggttc 1140 cccagagttt gttattgaac gtatgcaaac aggagaggtt tttcagatta tgctactaag 1200 ctctgtgccc gtgaatgtag taatacaacc gtactacatt gttagtgttg aatattaagg 1260 aggaaaacaa tggttaaagt taatgaacta aaagtcggag atgttttaat ttacacaggt 1320 gagtttaata gtgtaaattg gaggtttggc aaagagtacc ccgtgttcaa cggagacggt 1380 caactatatg ttttgacaga tatgcataat atgtatttta tttttgacca tgaggaatat 1440 attgagtcaa aatttgaact gaaagaaaag gaggctgtaa aggaaacggg aattgtacac 1500 aaagccaaaa tgtacgtgcg tttgaaaatt ttcccaatgg atggctctaa cgcgcgcgta 1560 aacgaaccac tcctacattt ctttctcagt ttttatgatt atgcagacac ctcaacatgg 1620 agaggcaaag aagttttcat acaagggtgg ataacaagcg ataacagacg taaactaata 1680 gaggaaattt ctaccttttt tggtctaggt gttgaggagt ggtaacgtgt tagaaagtac 1740 ctattcacaa aaagttaaac gatttgttga gtcacacggt gggatgttcc ttgtaaacac 1800 agcaagtgtt tatgacaaag caggacgctc tgacgttgaa ataatttaca aaggacatgt 1860 gatttttgca gagttgaaaa cagacgggta ccaaccaaca agcctacaaa tacgtttttt 1920 acaacgcgtg agagaacaag gcgtcatagg tctcatacta aaggatgaac tacaggagtt 1980 agaaactatt tttcacttga tagacacggg acacattagc acgtataaat tgccaaaatt 2040 accagagatt aaaacatatg acttatttga ggaggatgaa tagaatggaa ctaacattac 2100 atgattttga gtataacgag gatatgattg acgtatatga tttagatgat acgttagtgt 2160 tttatactag tgagaaaata gggagtagta cagtcaatac acagattaga ttagacaaga 2220 aggcacaaat ggaattatac aaggtattgg acaaacattt atttggtgac tatgatggta 2280 aagttatgga gtctctagaa ccttatgaga agacgggtga taggaacgtt atggagcctc 2340 tagaacccta tgagaagaca gatgatagca aagtaatgat tgacgctgag gagtttagag 2400 acaagattaa acatgataca acgatacgtg aggcagtggc ataccttgac ggatatgttg 2460 agggtaagaa aaatgactaa aattctacta atgattacta actcacgcgg tgatttgttt 2520 ctagagacca ttatggtcag aaactcagac aatataggcg aaattgttga taactatatg 2580 aaagagcgct accagagtgg cgtaacatat gtttgggaaa aagtaataga taattagaaa 2640 attctaataa aactctaatt gtattttaag tacagttaga gttttttata ttatacttag 2700 ttcataaagt taagggaggt aacagcatga taaacaaacg caataataaa gttattgatg 2760 ttattttcac agatgaggtg ttcggagggt tgtgaggtaa attagacgtt gagaatgaca 2820 taattattat aaaacttgag agcttagaaa aggcgctccc tactcgctat tggaatacgt 2880 ctataggcag tgaccaacta aaggagcttt ataacatggc tgtaaatggt ttcatatgtg 2940 caaacgctaa tgagtttgat tgggtacaaa taccagacga ctatttagga ggtaataagc 3000 aatgagtaat atgtttgagg taggtcacag agtagtatgt gtagacactt tatgtgtaga 3060 agatatattg gaaaaaggta aacgatatac cattgttgga gtaggcagcc ttttcgtgca 3120 ggttgatggt attgatgaat ggttctacta tgaccgtttt gaacgtgact atgttaatg 3179 <210> 75 <211> 797 <212> DNA <213> Artificial Sequence <400> 75 tcctcatact tcatacgcca actaatgtac gtcactctaa acattataca tcactcctgt 60 tctaatttct aagacctcaa ttcctaacac ttgttctaag gcaacaaact ctgtcttata 120 ctggttataa atcaatataa gaaaccctgt atcattgtca attaaccaag actctactcc 180 taaatgctct gtctctataa caccgtttcc cgcattgtag ttcttaatgt aaatattata 240 catataaaac ctcctcacac cactatttta tacaaaaaga gcgcacctgt caatagggta 300 cgctcacttt attattaaaa tggtaggtca tcatccggtg actcaatttt cacaggttct 360 aaaaaggctg agttacctga ctggtcaagc tcattcttac gtacaagaca gtcaattttc 420 acacctttag caaggaactc accctcactg tcttttacta atgcgttttc ccatgtgata 480 ggtgactcct caaaaatacc ctcaaaccgt tcacgtgctt tctttgcttt agcgtcatta 540 taaacaaact tattaatggt aggtacccac acgcttgtgt taaatgaaaa ctcatagaac 600 ttacctttgt aagctaccgt tacaatgcgt ccttttgagt tgtcacgaat gcgctcaata 660 acacagtctt ttaataattt attagccatc ttcgcactcg gtttttctac ctcaatgaag 720 ttactaggtt ctaaataagc tttaccgttg tcagaggtat atacctctaa tgtgtcacct 780 gtgttaggga caccacc 797 <210> 76 <211> 670 <212> DNA <213> Artificial Sequence <400> 76 agtggggtaa atgaaatgac accagaaaac gttgaaaaag agtacggtgt gtacgttgtt 60 ggaggagaca ttattgatat attagaccat gtttttccaa gctatgaaga agctttagaa 120 catgctaaga cattccatga atgtgatact gtaatagttg gagtagttca ggataaggat 180 gaagagtgat gagtttctta aatatatttt taccaacaat gatgatatgt attattattg 240 tagctgtagt tagtgccttt tggggactga tagcaggact ctctaaacta cttgattggc 300 tcattgctaa acttggagac agtggagagg taatttatat gattacttta gttggtttta 360 tagttccgtt tattctgtct gttgtgtttt gggtaattag taaaattgga ggtatgagtt 420 aatgtatatt attagtttgt ttattgtagt attagtgagc tacgcattag gttgggttct 480 atctaatttc tttggctttg tgtttgaacg catagcagag agaaatgttc atttagcaat 540 tttgtactta gttgttttag ttgctttact gattacagta ttggtttata tacttatgcg 600 tttgttctaa ggagtgatac aatgaaatac aaccaattta aggggtttcc tctcaaagcg 660 cgtactaaaa 670 <210> 77 <211> 466 <212> DNA <213> Artificial Sequence <400> 77 gctagggatt tggcctgtag tttcatgtgg ccttgctgga tgcccgtact taccaaggct 60 ttgagggctg caaaattttg atcaagaccg atggacacga taatctgggc taattctctg 120 gcagaaggat ttcctagtag atcatgactg agagctacac gtgggttgag gccgatagag 180 ccacccttag tctctacagg catgggcagg gtcatctcac cgaccaattc ttctctttca 240 aggtccagcg tccagcagct aagaccttga tagcgtccat ctcgactggc aaaggcatgg 300 gccccagctt cgatggcacg ccagtcatta ccagtggcaa tcaaaatcgc atcaatacca 360 ttaaaaattc ctttattatg agtagcagct cggtaaggat cagcctgcgc aaactgacta 420 gccaacgcaa ttttctccgc aatctctcgt ccttgatcct tttggc 466 <210> 78 <211> 459 <212> DNA <213> Artificial Sequence <400> 78 gtcttggtca ggccgtcggc gtcggttttg ccgatcacgg cggcttccag cacggcgggg 60 tggcgcacca gagtcgcctc cacttcgaac ggcgagacgt agatgccgct gactttgagc 120 atgtcgtcgt tgcggccggc gtagatgtag cggccgctgg cgtcgcgcgt gtatttgtcg 180 ccggtgcgcg tccaggcgcc ctggaaggtc tcgcgcgatt tgtcgcggtt gttccagtac 240 atcagcgcgg cgctggggcc gcgcacgtac aggtcgccga tgtcgatgga gccgtccggg 300 ttggcgggca gcgggcggcc gtcttcgccg cggatttcca gctcgtagcc gggcaccggg 360 gtgccgctgg tgccgtagac gacgtcgccg gggcggttgg agcagtagat gtgcagcatc 420 tcggtggagc cgatgccgtc gatgatttcg gtcccgaag 459 <210> 79 <211> 450 <212> DNA <213> Artificial Sequence <400> 79 gttgcggggt gacgaacgcg gggacctgta tctgcaggcc caggcgctgg agcgccttct 60 aagcccggcg ttcgcgctgg ttgatcacgt tgatggtttc cttcaccaag gcggccggga 120 tctgaccggc tacgaagacg gcacggaaaa ccccagtggc gatgacgcca tcgaggccgc 180 catcctgggt gaaggtgcgc cagggttgca ggggtcgagc ttcgccgcat ttcagctgtg 240 gaagcacgac atgcagtatt tcaaatcgct gcctcagcag gtgcaggaca acatcatcgg 300 ccgtcgcctg agcgacaacg aagagctgga tgatgcgccc gagtcagcgc atgtgaagcg 360 tactgcccag gaaagctacg cgcccgaagc tttcatggtg cgtcgctcgg tttcctgggc 420 tgacacccgc ggtgcgggac tggcatttgt 450 <210> 80 <211> 446 <212> DNA <213> Artificial Sequence <400> 80 gtcaggcccc ggcggggccg tgatctgaag ggccggagtc tgaccttcgc ccagcgggag 60 gagatcgcaa tactgcgtgc ccagggtcaa tctctgcggc agatcggagc cgtggtcggc 120 agagcggcct ccacggtttc ccgggagttg cggcgcaatt cggtggcagg gatgccctac 180 cgggcaacct cagcgcacgc actggcctat gaacgggcat cgcggccgaa accagcgaaa 240 ctgcacacca acacggtgct gcgagcgaag gtggaagagg acctgaaaaa gaagtactca 300 cccgagcaga tcgcaggacg actgcgggtt gaggtccccg acgagccgga gatgagggtg 360 tcacccgaga cgatctacca gtccctttac gtgcagtccc gcggggcgct gaagcgtgat 420 ctgaccgtgt gtctgcgcac cggacg 446 <210> 81 <211> 445 <212> DNA <213> Artificial Sequence <400> 81 gagcatcttt ctcaaggtca tgcagctagc atgtgataga actgaatcca gccaggcgtg 60 gtggctcatg cctgtaatcc cagcactttg ggaggctgag gcgggcagat tgcctgaagt 120 caggagttcg agaccagcct ggctaacatg gtgaaacccc atctctacta aaaatacaaa 180 aaaatttagc caggcgtgat ggcacatgcc tgtagtccca gctatttggg aggctgaggc 240 aggagaatca cttgaaccca ggaagtggag gttgcagtga gctgagattg caccaccgca 300 ttcctgcctg ggtgacagag caagattctg tctcaaaaaa aacaaacaaa caaacaaaca 360 gaaaaactga atccagggtt cctaaggcca gattttctgc tttaggagag tgcgtttcag 420 taatgggttt gtgtgtgtat gtgtt 445 <210> 82 <211> 432 <212> DNA <213> Artificial Sequence <400> 82 ctccccagac ccaacagaac gccttgacag aaaacaagct agattgaaaa cccgtaaaaa 60 agcgaagaag gcaaaaggct aaccactttt tagagggatg aatagtagtt gatgcagagg 120 taaaaggaat ggtaagtagt ttaaagtcac ggttgcagaa gttgaaggaa cacgcatcta 180 agacggaata cgcaacacaa gatgaatgtt tgtcgctata tgtggattgt ctgagattag 240 cttttcaaga caacggactg gatataaaca tggatgatta tattactcct ccatttggcg 300 acatcaaaca atcagactat aagagggcta aaaagagagt agaggaactt caaaacaagg 360 ttaaagaaag tgaggtgatt tagtatttga ccgagttaag cagaaaacaa gaaatattta 420 tgacaaacta cc 432 <210> 83 <211> 415 <212> DNA <213> Artificial Sequence <400> 83 ccggcgaact ctctgccctt tgcggcgaag gagtcgcgca tgagcgcgtg ctcgacaagc 60 agccgcttca gcgagaagca cagggcgagt ttgacggcgg tcgggtaggt gtcgttcgtg 120 ctctggctgc gattgacatc gtcgagtgga tgcagcagct cgtaactgcc cttctcctcg 180 ccagcgagtt ggagggcgac gttggctatc acctcgttgg tgttcatatt cgtcgaggtt 240 ccggcgccgc cctggatcac gcccacgacg aactgatcgt ggtactcgcc ctggcggatc 300 gcctcgcagg cggcctcgat catggccccc ttctccgggg cgagtactcc gatctcgacg 360 ttggctctgg cggcggcctg cttgacgatg acgagggcgt cgatcaggtc gggat 415 <210> 84 <211> 276 <212> DNA <213> Artificial Sequence <400> 84 tactagcacc cgcaaagtgt ccgccaaagc gcgcgtcata ttcagcctta cccttttcat 60 tcaccataat gcgtgtagcc gtaatttgtt gtttaaatac ctctggttct aaattataag 120 ggttcaagtc atcaatgaaa atcaactgtt tgtcaactag taacgcacta ttaaactcac 180 ctttggtgtt aaatgcgcgg ttagatggga gttctgtgta catttttcca aacaatggtg 240 agcctatgat tttggtcatt agaatagact ttccat 276 <210> 85 <211> 272 <212> DNA <213> Artificial Sequence <400> 85 ctatcaatat aaagaaacgt gtaatagatt agtagaggaa ttgtctaaag gtgatagacc 60 tatctcaata tataatggct ctattaagga cttagagaca tgggaacaac atgaggacgc 120 gattattttc aatttaaaag gcacgggggg tattttttag agcgtctaaa atatttctaa 180 ggtaattata cccagaacac ttagaacgta tctcagagcc tctcagagcg ttttagagca 240 tgtttgtttt tgagcgtaaa aaagagaggg tt 272 <210> 86 <211> 255 <212> DNA <213> Artificial Sequence <400> 86 aacctagaga ggacttaggt aaagattttc agatgattgt gtactttgtg gtagcagtag 60 tgtcagagtt agaaaacggg acatatagcg tggtttccta taaaccaatc gcacaagcac 120 ccatagactt aattaactgg ctaattgaga acgcaaagca acataattac ccaacgaacg 180 caacgccaaa ccaattaaac agaagtctag acgcatggtt taagatgtta gcgtatgaga 240 gtggtaaaat gggta 255 <210> 87 <211> 255 <212> DNA <213> Artificial Sequence <400> 87 tcatctgaaa caaaatcatg aaccactaga cccatgtcct caatttgttc atctgaaaag 60 tctaatgaca atacattaga accgtttctc tgcgtttcca atacagtagt agtatcagac 120 caatatgatt tagtttgaaa ttcactatct actagcatgt ttgtagatgt actttgtgtg 180 tttctaaatg ggtcacttaa aatagagtgt gccacaccct cagggcatga aaatgttaac 240 gtcaacggtg taatg 255 <210> 88 <211> 255 <212> DNA <213> Artificial Sequence <400> 88 ttcagttagc tattgagcga catgaacggg acttagagag gtcaaaatac ccatcgtttc 60 cgtatgaata tagaccagaa ttagcagaaa aaccaatcgc tttcattgac aacctaccag 120 accccaacag cggtaagagg gtaggactag cagactttca gaagttcatt attggtatga 180 tattttcatg ggttaaaaag gactcagggt acaggcgatt tactaaagtg gtaatctcca 240 tgagtcgtaa gaacg 255 <210> 89 <211> 255 <212> DNA <213> Artificial Sequence <400> 89 atacataacc cttacacact ggttaccttg tgagttacgc gctgttagac gtacatataa 60 gcgaccgttt gagtcatctt tctgcattgg aacaatcatg tcatcatcca cattaataat 120 gtaacccctg ttagaaacgc tgtacatatc aaaaggctcg tccatgggtt caaaccgttc 180 atgtttcgta ttaacgtttc tcatactttg taccaccttt gacagtcgta agctcagtaa 240 ttgacttact ttgtg 255 <210> 90 <211> 255 <212> DNA <213> Artificial Sequence <400> 90 tgtcactcca aacggaatct cagacaattg gctaccgctt actccctctc tattttcata 60 ccagtgggca attagaaaca ttgtagcaat atcaaagcgt gggtccgttg gttggtcctt 120 tacctcactg gctcccatca aaaaagaaac tgctgtttct tgtaacattg ttaaatactc 180 gtcatccata ttatggtcaa tgcgtagatt atttttaatt tggtcaattg ttagcattat 240 ctcactccta tctaa 255 <210> 91 <211> 255 <212> DNA <213> Artificial Sequence <400> 91 gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 60 gtacacaaag ccaaaatgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 120 cgcgtaatcg aaccactcct acatttcttt ctcagttttt atgattatgc agacacctca 180 acatggagag gcaaagaagt tttcatacaa gggtggataa caagcgataa cagacgtaaa 240 ctaatagagg aaatt 255 <210> 92 <211> 255 <212> DNA <213> Artificial Sequence <400> 92 tgttccacaa cttaaacagc taccaatttc aaaactagac gctggcatgc tagtcattta 60 ttgtaatact tacgctattt acagtcaggc aactcaagag gtatctgaat acggttatct 120 tgacgaacaa gggaaaccat caggcgcctt taaggttatg aatgaaacat ctaaacaact 180 aaagtctcta gcaagttcat taggactttc aattgatgga cgtatgaaat taattatccc 240 aagcatgaaa acgaa 255 <210> 93 <211> 255 <212> DNA <213> Artificial Sequence <400> 93 gtcaccaaac gggtctggtt gttctttcgt tttcatgctt gggataatta atttcatacg 60 tccatcaatt gaaagtccta atgaacttgc tagagacttt agttgtttag atgtttcatt 120 cataaccata aaggcgcctg atggtttccc tttttcgtca agataaccgt attcagatac 180 ctcttgagtt gcctgactgt aaatagcgta agtattacaa taaatgacta gcatgccagc 240 gtctagtttt gaaat 255 <210> 94 <211> 255 <212> DNA <213> NCIMB 43666 node 26 <400> 94 cgcaccttta ctttaccttt agcgtcaata ccaatataat tgtagacatc tttctggtat 60 aatgcaatga actcatcttt gtcaaataca atacctacgc gctcagaaat gtcatcacag 120 aacgcgtatg taatacgttc agcctcctca tcatgaggaa tgtaggcgtg acagtctgtg 180 ttgctctgta acatggtaac atggtcccta attccctcgt agaagtcagc cataattaat 240 tgcccaatca cacat 255 <210> 95 <211> 255 <212> DNA <213> NCIMB 43666 node 27 <400> 95 gtctactact aataatttgt tttgttcccc acataagacc cctttattca tgtttcttat 60 tttacctaat gttttgtaac tctcttgagc ttgccactct tttatcgcgg gaattttagt 120 acgcgctttg agaggaaacc ccttaaattg gttgtatttc attgtatcac tccttagaac 180 aaacgcataa gtatataaac caatactgta atcagtaaag caactaaaac aactaagtac 240 aaaattgcta aatga 255 <210> 96 <211> 255 <212> DNA <213> NCIMB 43666 node 28 <400> 96 cgtctagagg ctaaatatac agatgaaaca gagattacaa tgaacgaagt aacgttacca 60 aagtatgtgt tagtaaatgg ggtaaaattg cctattaata cattgtttgg tgccacaggt 120 gcagagtata atgggttata tgacccacgt tttcaatttc taacatgtgt gattgggcaa 180 ttaattatgg ctgacttcta cgagggaatt agggaccatg ttaccatgtt acagagcaac 240 acagactgtc acgcc 255 <210> 97 <211> 255 <212> DNA <213> NCIMB 43666 node 29 <400> 97 ttgtcaacta gtaacgcact attaaactca cctttggtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacaatggt gagcctatga ttttggtcat tagaatagac 120 tttccatgtc ctccggtgcg tgtaccgcgt gagacaacaa tttgagcatg aacagcctca 180 ggtttgttct catagacgca tgaccctatg aactcacata atgctttttc acttagtggg 240 tcagtaaaga agttg 255 <210> 98 <211> 255 <212> DNA <213> NCIMB 43666 node 30 <400> 98 tcataaaagt atgcttcact gtacgcgttt ataagcgcgt caagagggtc aatcttgttg 60 cggttaactt gtttatcaat cataattaca tcgtttgact cttttgtaaa tgcgttgtac 120 acggctcgtg tcaatagagg gttgttaaag tgaaggacct tgcccgctcg tatatccact 180 tgtaattgtt tagtaggtgg gtttaatcgc agataagact gacgtacatc aaagagtacg 240 tcctcatacc cgtct 255 <210> 99 <211> 255 <212> DNA <213> NCIMB 43666 node 31 <400> 99 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgtagc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg gggtctttcg agaaatcata 240 attcaatact aaatt 255 <210> 100 <211> 255 <212> DNA <213> NCIMB 43666 node 32 <400> 100 acccatctaa tacagatgag tctgaggcta gagctttaca aaaagagtca tcttttgtct 60 caatgtcata tttgtttact tttgtaaact cacgaacctg tttagatttc tttctaacag 120 cctgtaggtg tgtcttaatc atgcggaaac aaatagacgc ttggtctttt gtattggctg 180 tagaatatat ttgacgggac gccatgggcg aacgttcgta aagaagttca tataatgcaa 240 tacccgcgat taata 255 <210> 101 <211> 255 <212> DNA <213> NCIMB 43666 node 33 <400> 101 ttagacctaa tggaggcagt acagcaatat gagaaagtac gcgctgaggg aatgcgttta 60 caggagcaag aaatagaaaa gaaagtgact atacgcgtgg atggggaaca ggatgaattt 120 gaggatgtgt ttgttagtgt taagattgct aaaaatgatt taggtaacct tgatgttgcg 180 tatgagctag tataacaccg ttttacacat aaatggtata ataacactat atgaaataag 240 agagggagat tttaa 255 <210> 102 <211> 255 <212> DNA <213> NCIMB 43666 node 34 <400> 102 attttccata cttctcgcct ctcctttttc taatttgtcc acgtcttcct ctaatgcttt 60 agcacgttcc gcgtccacag atttatcttt attttcttct ggttcaacct cgtctgcctc 120 atcatccgta gggtgttcat ccttaggttg ctcgtcaggg ttaacctcgt ctgtttgttc 180 gtcttgtgcc tcacgaattt ccttgattaa tttatccgcc tcatctaatt taccttgtgc 240 gataagttca cgggc 255 <210> 103 <211> 255 <212> DNA <213> NCIMB 43666 node 35 <400> 103 agagtttcaa ttcaacaagg tcaccctcat tacccgtgtg ctcaaatagt ccactattaa 60 aggctaaatc aataacaggt gttttactac gtactaggtc ctcacgcatt tccttagcct 120 catcagagag cgtccacaca aactcgtctg cggtaacgtc ctctctgcgt ttcaatagtt 180 cagcatactc ctgtacacac catctaataa actcagcttt ctcctgttcg ttgtttagtg 240 cgtctctcat ctcag 255 <210> 104 <211> 255 <212> DNA <213> NCIMB 43666 node 36 <400> 104 ttggatacgt tgaaagacgc agacggacga tacattattc aaccaaacgt agcaatggca 60 agtggtaaaa cattgtttgg taaagaggta attgtacttc ctgacgctat ctttaaaatc 120 gacacaattg ataaactatt attcattggt gacttagaac aagctattac tttgttcaaa 180 cgtactgaca tgacggtacg ttggcaagac cacaatgtct acggtgaaat gttagcgggt 240 gccatccgtt ttgac 255 <210> 105 <211> 255 <212> DNA <213> NCIMB 43666 node 37 <400> 105 aactttatcc tctttatcca ggttctcagg cgtttcccat ctattggaca ttaggttcac 60 tctccttata agtgaaatca cttgcgaaaa atgaagcgta acgtttatca ttaatgtctg 120 tagggaagac ccaagttaaa tcacgagcct caatgtaaat gctatctgtt tctaagtcaa 180 gcaatgcctc acgtccaatg agtaactcct ccttacctac aggcggttct actgtacctg 240 taacaataac aggtg 255 <210> 106 <211> 255 <212> DNA <213> NCIMB 43666 node 38 <400> 106 gtgtttctct ttctcaatta atactttctc tgtaggtgtc aattcgtttt caggtagttc 60 gtacaagact gccccaattg gtaaaggtgt cgtctcgttg tttactaact catatgtttt 120 caatctattt cctcctctag tttatcaatt atattctcaa cttcatttaa taagtcctcg 180 ttatcatcat tttgctgtac tacgttaagc gcgtatagtg ctaattcagt aggtgagtca 240 ccgtcaatta ataca 255 <210> 107 <211> 255 <212> DNA <213> NCIMB 43666 node 39 <400> 107 tttgctacag gtgcattgta ggtaaatggg ttttttgtaa ctggtttaat tccgttgtgt 60 gattggatat gctcaaagtt ccaagtgaac ttcttacccg tttggtcacg tgtcattgta 120 cagcggaccc aagatgattt gtacttagtt acgtctgtct ggatagattt tagtaacttg 180 ttaccgtacc agtattcaac aatcacttca ttgccttttg cgtcagagtc acggatggct 240 atagacatta atatg 255 <210> 108 <211> 255 <212> DNA <213> NCIMB 43666 node 40 <400> 108 cctcgtctgc ctcatcatcc ttaggttgtt catccttagg ttgctcgtca gggttaacct 60 cgtctgtgtg ttcgtcttgt gcctcacgaa tttccttgat taatttatcc gcctcatcta 120 atttaccgtg tgcgataagt tcacgggctt ctagtaatcg tttatccatg tttcacactc 180 cttagtatgt ttcttaaata attataacac gcgtttatta accgcgggtg agttagctgt 240 atcacattaa ttcta 255 <210> 109 <211> 255 <212> DNA <213> NCIMB 43666 node 41 <400> 109 agcacttgta aacaactttt tacatccctt tttataaaat aatatggtat aatatgtgta 60 tacttattat acattgtttt tctccctaat aagcactaca cgctgattcc tcccaacgtg 120 tagtgctgtt tattattttg acgagttaag ttcgtcaatt gtgtcattgt atgcagtagc 180 tagtttattc atgaggtcac caatttttcc aattatttgg tctggttcat taccccctaa 240 aaggttaccc atatc 255 <210> 110 <211> 255 <212> DNA <213> NCIMB 43666 node 42 <400> 110 taacttaatg attagtacaa cctcacaaaa cctaaacgga cactatcata tggaggaata 60 tccaatgact atgaaagtat taacaggtga ggtagaggct gaacactact tagctctctg 120 gtgggaactg gatagttttg acgaggcgga tgacgaggaa aactggttta aatctaaccc 180 tctttttgaa aaacctgacg ttcgcacaca tatgttagaa cacacacggg ctaaaaagac 240 agagggagag gctaa 255 <210> 111 <211> 255 <212> DNA <213> NCIMB 43666 node 43 <400> 111 cccataaacc aacttagcgc aggtcaatat gacattaacc aacctctacc agtttgggct 60 agaccattga ataacgtaac actcattcat caaggttctg gaatgaacag gctactacta 120 gaagtgcaca aggatggtgc aattatagta agtaggtatg gtactacagt agatagtgcg 180 attccgtcag gcgcatggat aaacatctct tgcgtatatg cgggtcaaga tttattctaa 240 gggggataat tatgt 255 <210> 112 <211> 255 <212> DNA <213> NCIMB 43666 node 44 <400> 112 ttgttacaga gaacattgaa acacaatcta aaaaaggtaa cccaatgaga cgcctgaaac 60 tccgtgagac acgcacaggt agggaggctg tttcttactt aatgacttgg aaacctgatt 120 ttacacggtg ggaggacatt gagccactat cagtggtgag ggtagacatt gagttaaaag 180 atgggttcta taatttaggt aagcctgaaa ttgcaggcaa gggtgatgaa gttccaccgc 240 gtcccaataa accaa 255 <210> 113 <211> 255 <212> DNA <213> NCIMB 43666 node 45 <400> 113 gacagacgta actaagtaca aaacatcttg gttccgctgt acaatgacac gtgaccaaac 60 gggtaagaag ttcacttgga actttgagca tatccaatca aacaacggaa ttaaaccagt 120 tacaaaacac ccatttacct acactgcacc tgtagcaaac aaagcttccg ttgttaaaac 180 atctagatgg ctactcaagt ataaagactc agtagccaca agggaggtag tggataaggt 240 aacatggaca atgaa 255 <210> 114 <211> 254 <212> DNA <213> NCIMB 43666 node 46 <400> 114 ttgtcaacta gtaacgcact attaaactca ccttttgtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacaatggt gagcctatga ttttggtcat tagaatagac 120 tttccagttc ctccgttgcg tgtaccgcgt gagacaacaa tttgagcatg aacagcctca 180 ggtttgttct catagacgca tgaccctatg aactcacata atgctttttc acttagtggg 240 tcagtaaaga agtt 254 <210> 115 <211> 254 <212> DNA <213> NCIMB 43666 node 47 <400> 115 tccgtctgtt agacccgcaa aagtgcccac taatgaggtg accgcaccga ttaccgcgcc 60 accttttaga gacattacac catctaatag tccacctacc ccatctgtag cctcgtctgc 120 tccaccattg atgtcactaa gtccatcact agcgttctcc attgatttaa gagctttact 180 tgataattta gcctgtgact ctaatttaga tagggagatt ctagcctcct caacttcttt 240 agagttttca ccga 254 <210> 116 <211> 254 <212> DNA <213> NCIMB 43666 node 48 <400> 116 atttcctcaa ggctacccaa accctcagca actagttcgt tagccatttg agtgtagttt 60 tctgcgccct cttgtgaaag acctaatgca ccttgaaact tattgatggc gtcttttgat 120 tcattgagtc cgtctgttag acccgcaaaa gtgcccacta atgaggtgac cgcaccgatt 180 accgcgccac cttttagaga cattacacca tctaatagtc cacctacccc atctgtagcc 240 tcgtctgctc cacc 254 <210> 117 <211> 254 <212> DNA <213> NCIMB 43666 node 49 <400> 117 ttcttacccg tttggtcacg tgtcattgta cagcggaacc aagatgattt gtacttagtt 60 acgtctgtct tgatagattt tagtaacttg ttaccgtacc agtattcaac aatcacttca 120 ttgccttgtg cgtcagagtc acggatggct atagacatta atatgtcatt agcgtctgtc 180 aaaataacca actcataacg tccgttcttt tctgacgtag taccgaagtc tatccgttcc 240 tcaaatttaa aggc 254 <210> 118 <211> 254 <212> DNA <213> NCIMB 43666 node 50 <400> 118 catggcatta gagtcaaagc cattgagtat tgcaaacgta caggatggtc aaaatccatt 60 tttacacaca gcttacgcat ggagtagtga tggaaaagag aggttcacac tccaataccc 120 aaatgatcat ttagtattga attatgattt ctcgaaagac cccactatta atggttggac 180 aggaaatggt gcgactatag aatattcaaa cgggaacatg cgagtgttgt ttaacgactc 240 atcaactaac agaa 254 <210> 119 <211> 254 <212> DNA <213> NCIMB 43666 node 51 <400> 119 gcctttaaat ttgaggaacg gatagacttc ggtactacgt cagaaaagaa cggacgttat 60 gagttggtta ttttgacaga cgctaatgac atattaatgt ctatagccat ccgtgactct 120 gacgcaatag gcaatgaagt gattgttgaa tactggtacg gtaacaagtt actaaaatct 180 atcaagacag acgtaactaa gtacaaatca tcttggttcc gctgtacaat gacacgtgac 240 caaacgggta agaa 254 <210> 120 <211> 254 <212> DNA <213> NCIMB 43666 node 52 <400> 120 agcgtttgtt tggttaaatg cttgtttatc aaggttgaac atggcacaaa taaacgcttt 60 agcaagtaac ccaacaacac aaccaaagaa gcggagctca gtggcgtctc cgtctttcca 120 acaagacgca acctctttgc gttgttcctc atctgttagt ttaccgcctt gttcaaagtc 180 aacatccgtc tcttagactt ctaaccccat gaaaccctca tgttctttca gtgaaaaccc 240 tttgtgttca tggt 254 <210> 121 <211> 254 <212> DNA <213> NCIMB 43666 node 53 <400> 121 tcagttagct attgagcgac atgaacggga cttagagagg tcaaaatacc catcgtttcc 60 gtatgaatat agaccagaat tagcagaaaa accaatcgct ttcattgaca acctaccaga 120 ccccaaacgc ggtaagaggg taggactagc agactttcag aagttcatta ttggtatgat 180 attttcatgg gttaaaaagg actcagggta caggcgattt actaaagtgg taatctccat 240 gagtcgtaag aacg 254 <210> 122 <211> 254 <212> DNA <213> NCIMB 43666 node 54 <400> 122 cgccaaagcg cgcgtcatat tcagccttac ccttttcatt caccttaatg cgtgtagccg 60 taatttgttg tttaaatacc tctggttcta aattataagg gttcaattca tcaatgaaaa 120 tcaactgatt gtcaactagt aacgcactat taaactcacc ttttgtgtta aatgcgcggt 180 tagatgggag ttctgtgtac atttttccaa acaatggtga gcctatgatt ttggtcatta 240 gaatagactt tcca 254 <210> 123 <211> 254 <212> DNA <213> NCIMB 43666 node 55 <400> 123 tagttgggtt acttggagct gtagcactaa taaaaattga gtctctaccc gtgtatgagc 60 tagttactac ccaatttgta tacgtaccat ttgaaagcgt atttctactc cttacccaca 120 accacatccc aatttgaggt gttggacgtg ttgtactcca tcctgaggta ggttctacag 180 aactagttgt ttgtacatac tctgattgag taccagtcac actaatacca tcctgaccaa 240 agcgcgccac tgag 254 <210> 124 <211> 254 <212> DNA <213> NCIMB 43666 node 56 <400> 124 tatactctgt catttaccca caagcgcaag agtttaaaag tggtgatagt gataataaag 60 taggtacgtt cttaggtaaa gttggggaca aggtatacga acttgtcaaa ggtaaccctc 120 aatttacaga gggatatttc aacgatagaa cgaacgataa gtacagatac cttggtgaat 180 gtgcgtattt tcaaaacggt gcgctaaaca tgcgtacatt agaactacgt ccgtttgaac 240 catgggacta taga 254 <210> 125 <211> 254 <212> DNA <213> NCIMB 43666 node 57 <400> 125 ctcaagcgtt gatgaaccta catcaggatg gagtacaacc atcccaactc tagaaaaagg 60 taaataccta tggacacgta caacgtggga gtacactgat ggtacaacat cagtagccta 120 tacagtgtac tatattcctg tagatggctc aaccggtaat ggtgtgaaat ctatcgctgt 180 tacttacgct gtaggtacct caggtacaac agcaccatcc acaggttggc aagcaacacc 240 accaaatgta acag 254 <210> 126 <211> 254 <212> DNA <213> NCIMB 43666 node 58 <400> 126 gccatcttat aacctcctca taatgttctc attctattat aacataattc taattaaaaa 60 agttgatgac agtcattgac aaaataaatt taatatatta tattattagt ataatcagta 120 tagggagtaa cttcataatg agaaaagagt tgaaaaaaca cattaagcag atgaacccac 180 aagagattgt aactgttgtg aatatggttg agagcgctac aagaggaatg tgtaaagaga 240 caattaggac tagt 254 <210> 127 <211> 254 <212> DNA <213> Artificial Sequence <400> 127 tggatggtgc tgttgtacct gaggtaccta cagcgtaagt aacagcgata gatttcacac 60 cattaccggt tgagccatct acaggaatat agttcactgt ataggctact gatgttgtac 120 catcagagta ctcccacgtt gtacgtgtcc ataggtattt acctttttct agagatggga 180 ttgttgtact ccatcctgat gtaggttcat caacgcttga ggtattgatt gcccactctg 240 ttttagttga tttg 254 <210> 128 <211> 254 <212> DNA <213> Artificial Sequence <400> 128 gtactgagag cgtcaaaatt acctacccta attaacccat tattgttgct gaatgcgtct 60 attgtgacgg aatatttaac tcctgctggc aagtagttgg ttaataagtc attgctataa 120 tagactcgtc tgttagttga tgagtcgtta aacaacactc gcatgttccc gtttgaatat 180 tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga gaaatcataa 240 ttcaatacta aatt 254 <210> 129 <211> 254 <212> DNA <213> Artificial Sequence <400> 129 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt aggtaatttt 240 gacgctctca gtac 254 <210> 130 <211> 254 <212> DNA <213> Artificial Sequence <400> 130 ttcttacccg tttggtcacg tgtcattgta cagcggaacc aagatgattt gtacttagtt 60 acgtctgtct tgatagattt tagtaacttg ttaccgtacc agtattcaac aatcacttca 120 ttgcctagtg cgtcagagtc acggatggct atagacatta atatgtcatt agcgtctgtc 180 aaaataacca actcataacg tccgttcttt tctgacgtag taccgaagtc tatccgttcc 240 tcaaatttaa aggc 254 <210> 131 <211> 254 <212> DNA <213> Artificial Sequence <400> 131 gggaggactg acatgactga ggtgtttata aacgggaaaa ctatgacagt cacaactgag 60 gttgacaacc aaggttatac cgctcagttt gagattcact attgcccaat gtgcggtggt 120 aagctgaatg gaggaggttt ttgacgttta cttacaacct gaggaggtat tttaatgttt 180 aaggttgaac atgttagatt aacagaatat aatgacgcct atatgagtgt actgttgttt 240 aggcagaaag tacg 254 <210> 132 <211> 254 <212> DNA <213> Artificial Sequence <400> 132 cgttcttacg actcatggag attaccactt tagtaaatcg cctgtaccct gagtcctttt 60 taacccatga aaatatcata ccaataatga acttctgaaa gtctgctagt cctaccctct 120 taccgcggtt ggggtctggt aggttgtcaa tgaaagcgat tggtttttct gctaattctg 180 gtctatattc atacggaaac gatgggtatt ttgacctctc taagtcccgt tcatgtcgct 240 caatagctaa ctga 254 <210> 133 <211> 254 <212> DNA <213> Artificial Sequence <400> 133 tctatagtcc catggttcaa acggacgtag ttctaatgta cgcatgttta gcgcaccgtt 60 ttgaaaatac gcacattcac caaggtatct gtacttatcg ttcgttctat cgttgaaata 120 tccctcagta aattgagggt tacctttgac aagttcgtat accttgtccc caactttacc 180 taagaacgta cctactttat tatcactatc accactttta aactcttgcg cttgtgggta 240 aatgacagag tata 254 <210> 134 <211> 253 <212> DNA <213> Artificial Sequence <400> 134 atttccttga ttaatttatc cgcctcatct aatttacctt gtgcgataag ttcacgggct 60 tctagtaatc gtttatccat gtttcacact ccttattatg tttcttaaat aattataaca 120 cgcgtgtatt aaccgcgggt gagttagctg tatcacatta attctaaaat gtcaagttct 180 aattctaatt ttcttttttg ttctttaaac gctttttgtg accgttgtgc cactgctaca 240 gttgtatcat cat 253 <210> 135 <211> 253 <212> DNA <213> Artificial Sequence <400> 135 atgagacaac agcagtggag cgtctaagga gtattatttc agactttgga ggcgctaagt 60 ttaccattga ctttgagttt gaaaacatgc agttaaaaag taaaacaatg aacattgtag 120 aggatctggg ggacgagaaa gatattactc tacgtgttgg gcgtgacgta gattcaatcg 180 taactacagg taacatttat gagttaacta cagcaatacg agcattaggt ggtacaccag 240 aggggtcaaa caa 253 <210> 136 <211> 253 <212> DNA <213> Artificial Sequence <400> 136 ataataatgt tgaaagcaag tttttcctca tctacttttt taccgtattt caacttatca 60 aaatcaaact ttagttcctg taagacgttc tcaaacgctt tgtgtgtttc ttctttattc 120 atctgatttc ctcctaatgt tttaatacat ttattagttt atcaaaaccc caaccagttg 180 tcaagcatta tttttaaatt tcttgtaaat gttcgtacgg aatgagctga cgtataccat 240 caatcgttct aca 253 <210> 137 <211> 253 <212> DNA <213> Artificial Sequence <400> 137 tgtagaacga ttgatggtat acgtcagctc attccgtacg aacatttaca agaaatttaa 60 aaataatgct tgacaactgg ttggggtttt gataaactaa taaatgtatt aaaacattag 120 gaggacaaca gatgaataaa gaagaaacac acaaagcgtt tgagaacgtc ttacaggaac 180 taaagtttga ttttgataag ttgaaatacg gtaaaaaagt agatgaggaa aaacttgctt 240 tcaacattat tat 253 <210> 138 <211> 253 <212> DNA <213> Artificial Sequence <400> 138 tgacgtttgg ttgtttcaaa cgtgacgccc ttaggtaaca gaccgtatga cttgtaacta 60 gtcttggaac ctgcacgaat gtgtaggact tccttagatt tcattgtcca tgttacctta 120 tccacgacct cccttgtggc tactgagtct ttatacttga gtagccatct agatgtttta 180 acaacggaag ctttgtttgc tacaggtgca ttgtaggtaa atgggttttt tgtaactggt 240 ttaattccgt tgt 253 <210> 139 <211> 253 <212> DNA <213> Artificial Sequence <400> 139 tgacacgcaa gaagctccta aatggtccag actcttatca accaccggag gtttgttcac 60 acgtgatgta acgtatgaca cccttgataa aggtaaattg gcttcacttg ctgttagtga 120 cttgaaatag acaagtcaac ctgcttttaa gtatgaagga aacgtagtcg atgtaccttc 180 tgatttaaat gtaggcgata ggataaacat tgtagatgaa aaagatgaat tgtatctatc 240 aggtaaagct cta 253 <210> 140 <211> 253 <212> DNA <213> Artificial Sequence <400> 140 tagggttgtc actaatgttt tctaaatggt tgtttcaacc aaataaggga ggaaaataga 60 catgaattta gatactacaa aattaggtga tttagtggtt gaaaaggcgc gtgagttaaa 120 tgagaaaccg ggtattgagt ctgctgagtt acttgtcttc agtgctttag taactgtgac 180 taatgttatt gatactgtat taattgacgg tgactcacct actgaattag cactatacgc 240 gcttaacgta gta 253 <210> 141 <211> 253 <212> DNA <213> Artificial Sequence <400> 141 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tccggtccaa ccattaagag tgtggtcttt cgagaaatca taattcaata 120 ctaaagtatc atttggttat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg tataaatgga ttttgaccat cctgtacgtt tgcaatactc aatggctttg 240 actctaatgc cat 253 <210> 142 <211> 253 <212> DNA <213> Artificial Sequence <400> 142 tgtacctgct attaaaacca cgtcacctca atcgtttcaa tactactgga acattgtcat 60 gagagacacg ggctttacat tgggcgcaaa ctactttagt aatcagacac gtactttaaa 120 ctatgatcat gagacaacag cagtggagcg tctaaggagt attatttcag actttggagg 180 cgctaagttt accattgact ttgagtttga aaacatgcag ttaaaaagta aaacaatgaa 240 cattgtagag gat 253 <210> 143 <211> 253 <212> DNA <213> Artificial Sequence <400> 143 agaaaagtca acctgctttt aattatgaag taaacgtagt caatgtacct tctgatttaa 60 atgtaggcga taggataaac attgtagatg aaaaagatga attgtatcta tcaggtaaag 120 ctctatcaat tgaccgctgt agcgcagacg ataccgtcac attaacatta ggtgattttc 180 gtattcaata ttcaggtatt gaccctcagt tgctacagat agcgtcagat ttttctaaac 240 agtttgacaa cag 253 <210> 144 <211> 253 <212> DNA <213> Artificial Sequence <400> 144 aaaagtcaac ctgcttttaa ttatgaagta aacgtagtca atgtaccttc tgatttaaat 60 gtaggcgata ggataaacat tgtagatgaa aaagatgaat tgtatctatc aggtaaagct 120 ctaacaagtg accgctgtag cgcagacgat accgtcacat taacattagg tgattttcgt 180 attcaatatt caggtattga ccctcagttg ctacagatag cgtcagattt ttcaaatcag 240 tttgacaaca gta 253 <210> 145 <211> 253 <212> DNA <213> Artificial Sequence <400> 145 atagatacaa ttcatctttt tcatctacaa tgtttatcct atcgcctaca attaaatccg 60 aaggtacatt gactacgttt acttcataaa taaaagcagg ttgacatttc attttcaatt 120 cactaccagc aagtgaagcc aatttacctt tatcaagggt gtcatacgtt acagcacgtg 180 tgaacaaacc tcctgttgtt gataagagtc tggaccattt aggagcttct tgcgtgtcaa 240 tcataacccc att 253 <210> 146 <211> 253 <212> DNA <213> Artificial Sequence <400> 146 aatggggtta tgattgacac gcaagaagct cctaaatggt ccagactctt atcaacaaca 60 ggaggtttgt tcacacgtgc tgtaacgtat gacacccttg ataaaggtaa attggcttca 120 cttgcggtta gtgaattgaa aaagaaaagt caacctgctt ttaattatga agtaaacgta 180 gtcagtgtac ctgctgatgt aaatgtaggc gataggatca acattgtaga ggaaaaagat 240 gaattgtatc tat 253 <210> 147 <211> 253 <212> DNA <213> Artificial Sequence <400> 147 tagacgagtg ggaaaaggcg tacacagacg aggagtttga catcacaggg cgtgaagtat 60 ttattggtat agacctagca cgagtaaatg acttgaccgc tgttacgtgg gttattccta 120 tccctgacaa agaattgttt attgttgact ctcacgcgtg ggtagcaaca acgggtggtg 180 gtattgttca gaaagaggct aacgatagaa caccctatag acaatattcc aaacaggggt 240 attgtgaaat ttc 253 <210> 148 <211> 253 <212> DNA <213> Artificial Sequence <400> 148 tcttgtgttc cacacgttta gtgttttgta ggtaatatcc actgacccat cctgaggcag 60 gtattttctt acctgagttc ttagttacat aataccattg gttgttttta ataatctttt 120 gacccgtgtg acgtttggtt gtttcaaacg tgacgccctt aggtaacaga ccgtatgact 180 tgtaactagt cttggaacct gcacgaatgt gtaggacttc cttagatttc attgtccatg 240 ttaccttatc cac 253 <210> 149 <211> 253 <212> DNA <213> Artificial Sequence <400> 149 atgatgatac aactgtagca gtggcacaac ggtcacaaaa agcgtttaaa gaacaaaaaa 60 gaaaattaga attagaactt gacattttag aattaatgtg atacagctaa ctcacccgcg 120 gttaagaaac gcgtgttata attatttaag aaacataata aggagtgtga aacatggata 180 aacgattact agaagcccgt gaacttatcg cacaaggtaa attagatgag gcggataaat 240 taatcaagga aat 253 <210> 150 <211> 253 <212> DNA <213> Artificial Sequence <400> 150 tattgttgga aagacgtaga cgccactgag ctacgcttct atggttgtgt tgatgggtta 60 cttgctaaag cgtttatttg tgccatgttc aaccttgata aacaagcatt taaccaaaca 120 aacgctcatt tagtagctca attaatgggt gccaaccgtc ctaatagtgt acgtgatgac 180 cttactgaac catttacatt acctgaaaac attcatgtaa ctataccaga gattagagta 240 atgtttttag acc 253 <210> 151 <211> 253 <212> DNA <213> Artificial Sequence <400> 151 gacttgttca aagactccct gtactaatgg taataagtcc tcaaaggcta cgttatccac 60 taacatatca taagtaagtt ttgtgtttga gaaaatggag agaactaagt ttagcatatc 120 atctataacc tcaatctcat tcatttgtaa ctcacctttt tcaacctttt ccattttact 180 gtagtatgct aaaatctcgc gcattgttcg tacagttact ttctccgctg taaatgtttg 240 ttttttacct ttt 253 <210> 152 <211> 253 <212> DNA <213> Artificial Sequence <400> 152 gacttgttca aagactccct gtactaatgg taataagtcc tcaaaggcta cgttatccac 60 taacatatca taagtaagtt ttgtgtttga gaaaatggag agaactaagt ttagcatatc 120 atctatatcc tcaatctcat tcatttgtaa ctcacctttt tcaacctttt ccattttact 180 gtagtatgct aaaatctcgc gcattgttcg tacagttact ttctccgctg taaatgtttg 240 ttttttacct ttt 253 <210> 153 <211> 253 <212> DNA <213> Artificial Sequence <400> 153 tagggttgtc actaatgttt tctaaatggt tgtttcaacc aaataaggga ggaacataga 60 catgaattta gatactacaa aattaggtga tttagtggtt gaaaaggcgc gtgagttaaa 120 tgagacaccg ggtattgagt ctgctgagtt acttgtcttc agtgctttag taactgtgac 180 taatgttatt gatactgtat taattgacgg tgactcacct actgaattag cactatacgc 240 gcttaacgta gta 253 <210> 154 <211> 253 <212> DNA <213> Artificial Sequence <400> 154 ttacctttta caaagtttgg cactggttga cccgtttggt atttagttgc tttggcgcgt 60 acttttactt tactacctac agggaaatca cgtgtgtctg tgatttttgg tttagacggt 120 tgtgggtgtg gtttaggttt gttgtcagta ttggaactat ttccaccaaa cccattttta 180 atgtctttag caaactgctc tttactaatt ccccatttac gcaagtatgg ataggggtca 240 atatggtcag aac 253 <210> 155 <211> 253 <212> DNA <213> Artificial Sequence <400> 155 atttccttga ttaatttatc cgcctcatct aatttacctt gtgcgataag ttcacgggct 60 tctagtaatc gtttatccat gtttcacact ccttattatg tttcttaaat aattataaca 120 cgcgtgtctt aaccgcgggt gagttagctg tatcacatta attctaaaat gtcaagttct 180 aattctaatt ttcttttttg ttctttaaac gctttttgtg accgttgtgc cactgctaca 240 gttgtatcat cat 253 <210> 156 <211> 253 <212> DNA <213> Artificial Sequence <400> 156 ataataatgt tgaaagcaag tttttcctca tctacttttt taccgtattt caacttatca 60 aaatcaaact ttagttcctg taagacgttc tcaaacgctt tgtgtgtttc ttctttattc 120 atctgatgtc ctcctaatgt tttaatacat ttattagttt atcaaaaccc caaccagttg 180 tcaagcatta tttttaaatt tcttgtaaat gttcgtacgg aatgagctga cgtataccat 240 caatcgttct aca 253 <210> 157 <211> 253 <212> DNA <213> Artificial Sequence <400> 157 atagatacaa ttcatctttt tcatctacaa tgtttatcct atcgcctaca tttaaatcag 60 aaggtacatt gactacgttt acttcataat taaaagcagg ttgacttttc tttttcaatt 120 cactacccgc aagtgaagcc aatttacctt tatcaagggt gtcatacgtt acagcacgtg 180 tgaacaaacc tcctgttgtt gataagagtc tggaccattt aggagcttct tgcgtgtcaa 240 tcataacccc att 253 <210> 158 <211> 252 <212> DNA <213> Artificial Sequence <400> 158 ttatgattga taaacaagtt aaccgcaaca agattgaccc tcttgacgcg cttataaacg 60 cgtacagtga agcatacttt tatgagttcg aggaaataaa ctggtcagaa cgttacgcaa 120 gcggggattt tggttttgga ctgtaataaa cgaacgaggc aacccaacta gggttgtctt 180 tttcgtgtta taatttataa agaagttata attggaggag gttcaccatg gaacgaatta 240 tatatttacc ta 252 <210> 159 <211> 252 <212> DNA <213> Artificial Sequence <400> 159 ttgatgtagg agaacatttc ctacagttca ttaactcaga ttgggctaca gacactttag 60 aagtaactgt gaagaaccaa cgaacctact tgtaataaca tctagccact cgccaaagag 120 tggctttatt atggtataat taataaagaa acaagtgtaa ggggggtttt taaaatagaa 180 ttttatttta ctgataggga atttaaccct ataggaattg cgtccacaga tggagcagga 240 ctcattaaaa tg 252 <210> 160 <211> 252 <212> DNA <213> Artificial Sequence <400> 160 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaacttatc atttgggtag tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat cctgtacgtt tgcaatactc aatggctttg 240 actctaatgc ca 252 <210> 161 <211> 252 <212> DNA <213> Artificial Sequence <400> 161 ttatgattga taaacaagtt aaccgcaaca agattgaccc tcttgacgcg cttataaacg 60 cgtacagtga agcatacttt tatgagttcg aggaaataaa ctggtcagaa cgttacgcaa 120 gcggggagtt tggttttgga ctgtaataaa cgaacgaggc aacccaacta gggttgtctt 180 tttcgtgtta taatttataa agaagttata attggaggag gttcaccatg gaacgaatta 240 tatatttacc ta 252 <210> 162 <211> 251 <212> DNA <213> Artificial Sequence <400> 162 tgtgccacgt gttagcattg gtctgttaat aacaacgtgt gcattaccat atacatttag 60 gctcaatctg agaactttag tagcttcatt ttgaatggta tatgtttgcg tggtgcgagt 120 cattggactt gtagacgcgt ctagtcctgt gccaattgaa taccacgtat atagtttacc 180 acgttctgta atgtgttgga tgaacggggt agcatggtca ttttgttcta gtttaaagtt 240 ttttacgtaa a 251 <210> 163 <211> 251 <212> DNA <213> Artificial Sequence <400> 163 caattcctga ctctagaatg tcaaacccca cagcgtgtgc gtgcagtaca ttgtaagcaa 60 acattagacg agcgtgtatc ataatgtcta attctttagg ctcgtccata atgcgggcac 120 gcacttcatc taaaacattg tctaactccg cgtcatgtaa ttctaatacc tctgctaatt 180 ttgtcatatt atttttcctc ctcatagtct aatacctcaa tttggttatc atatacccac 240 cataggtgac c 251 <210> 164 <211> 251 <212> DNA <213> Artificial Sequence <400> 164 tcttacccta ttttggaaac aactaacgcg gtaatgaaca cagtagctga gttagtagaa 60 aaccctaaat tggcagaacc aacattcaaa aatgtagaat ggaaggtaga aacacaccgc 120 ggatatagtc caatgtctaa cgaagcaatt caagactctg accctgactt agttgcgttg 180 attgctcgcc acttaacacg tattgggttg aacacaatca ataaagcagt aatgactgag 240 ttactagcta a 251 <210> 165 <211> 251 <212> DNA <213> Artificial Sequence <400> 165 aatgacatta gtgagccatt tgtcaggttt agtacatact ctagtgtgct ttattagtaa 60 cacacttgat tctgaaccgc ttacaggtgt gtttctagcc tgtattagtg cttcacctct 120 aattgcagtg tgtatgtggc ttgatgataa atagaatatt ctcattaaac tctaatggtt 180 ttttaattga ctattagagt ttaattgttt atactaggtt cataaggttg agggttaagc 240 ctacggggtg a 251 <210> 166 <211> 251 <212> DNA <213> Artificial Sequence <400> 166 ttaattgacg gtgactcacc tactgaatta gcactatacg cgcttaacgt agtacagcaa 60 aatgttgata acgaggactt attaaatgaa gttgagaata taattgataa actagaggag 120 gaattagatt gaaaacatat gagttagtaa acaacgagac gacaccttta ccaattgggg 180 cagtcttgta cgaactacct gaacacgaat tgacacctac agagaaagta ttaattgaga 240 aagagaaaca c 251 <210> 167 <211> 251 <212> DNA <213> Artificial Sequence <400> 167 gggtaagaag ttcacttgga actttgagca tatccaatca aacaacggaa ttaaaccagt 60 tacaaaaaac ccatttacct acaatgcacc tgtagcaaac aaagcttccg ttgttaaaac 120 atctagaggg ctactcaagt ataaagactc agtagccaca agggaggtag tggataaggt 180 aacatggaca atgaaatcta aggaagtcct acacattcgt gcaggttcca agactagtta 240 caagtcatac g 251 <210> 168 <211> 251 <212> DNA <213> Artificial Sequence <400> 168 aaaagtctca atcacaaaca caagtacaga caactgggtg cggtattctg ctagtataac 60 tacccaaaat aaagcaatca ataagataga agtgctgttt gttatagacc cttcgtttgt 120 aggtacgatt tacgtaaaaa actttaaact agaacaaaat gaccatgcta ccccgttcat 180 ccaacacatt acagaacgtg gtaaactata tacgtggtat tcaattggca caggactaga 240 cgcgtctaca a 251 <210> 169 <211> 251 <212> DNA <213> Artificial Sequence <400> 169 tgtgtatgtg gcttgatgat aaatagaata ttctcattaa actctaatgg ttttttaatt 60 gactattaga gtttaattgt ttatactagg ttcataaggt tgagggttaa gcctacgggg 120 tgaccgagta ccaaccaata aagacaaggg atggttaatt atgattaagg tgatgaattg 180 ggagtatgaa tatggaatga aacgagtagc attctacaaa gaaattggtc atgagattga 240 gcttttagat a 251 <210> 170 <211> 251 <212> DNA <213> Artificial Sequence <400> 170 tcaaagagct agaatcacgt aacacatggc ttactagaac aaccgtagga gcaattatca 60 ctggtgtagt gggtgcaatt ttggcattca tcactggtta aatatatgat ataatagata 120 agacagggga cctgacatat gaaatatatt aactggcgcg tgaggattag caaggacaat 180 atcttattct gggtacgatt catcattggt gtaattactc ccgctttagc atacttagcg 240 ctagaacctc a 251 <210> 171 <211> 251 <212> DNA <213> Artificial Sequence <400> 171 cacaaggtgg agcaattgac accacagcaa cagggtcagg ggtagaccgt tggcgtgcaa 60 ctgctaaacg agccttacag atgacaggac aatggacaac cgcaaaccta aacgcgctga 120 tgacccaaat gcgtacagag tccaatggta accccaaagc tatcaaccta tgggacatta 180 atgctcagaa tggtattccg tcaaaaggtc taatgcaggt gattgaccct acattcagac 240 aatatgcaat g 251 <210> 172 <211> 251 <212> DNA <213> Artificial Sequence <400> 172 ggtaattaat tgagactgtg cagggtcata acaaatacct tgtacgtcta aattgtttgt 60 ctcaataaac gccaaaaccc aatttaacat atcctcccaa tcacactgac cgtcaggacg 120 ggaagaactt tcacaatacc cctgtttgga atattgtcta tagggtgttc tatcgttagc 180 ctctttctga acaataccac cacccgttgt tgctacccac gcgtgagagt caacaataaa 240 caattctttt t 251 <210> 173 <211> 251 <212> DNA <213> Artificial Sequence <400> 173 tattgacgca cgtttagagg acgtgagaga gattaaaaaa gagctgtctg gtgcccgtca 60 acaaatcgcg gacctagaca aacgtctttc gcagtcaatt gaccatgtta acaaactaga 120 ggacgacctc aaagagctag aatcacgtaa cacatggctt actagaacaa ccgtaggagc 180 aattatcact ggtgtagtgg gtgcaatttt ggcattcatc actggttaaa tatatgatat 240 aatagattag a 251 <210> 174 <211> 251 <212> DNA <213> Artificial Sequence <400> 174 gtattattag aatataatta gaaaaggaag tgtttataat gggtacaatt attctaggtg 60 ttattttggc aatttcattg atgttaaatg tgcgttatag tgtagagcgc aaatacttag 120 tcgacatcat ggaggcacaa agtaagtcaa ttactgagct tacgactgtc aaaggtggta 180 caaagtatga gaaacgttaa tacgaaacat gaacggtttg aacccatgga cgagcctttt 240 gatatgtaca g 251 <210> 175 <211> 251 <212> DNA <213> Artificial Sequence <400> 175 ggtcacctat ggtgggtata tgataaccaa attgaggtat tagactatga ggaggaaaaa 60 taatatgaca aaattagcag aggtattaga attacatgac gcggagttag acaatgtttt 120 agaagaattg cgtgcccgca ttatggacga gcctaaagaa ttagacatta tgatacacgc 180 tcgtctaatg tttgcttaca atgtactgca cgcacacgct gtggggtttg acattctaga 240 gtcaggaatt g 251 <210> 176 <211> 251 <212> DNA <213> Artificial Sequence <400> 176 ctcaaggcta cccaaaccct cagcaactag ttcgttagcc atttgagtgt agttttctgc 60 gccctcttgt gaaagaccta atgcaccttg aaacttattg atggcgtctt ttgattcatt 120 gattccgact gttagacccg caaaagtgcc cactaatgag gtgaccgcac cgattaccgc 180 gccacctttt agagacatta caccatctaa tagtccacct accccatctg tagcctcgtc 240 tgctccacct t 251 <210> 177 <211> 251 <212> DNA <213> Artificial Sequence <400> 177 tcatcagcgc gtttaggttt gcggttgtcc attgtcctgt catctgtaag gctcgtttag 60 cagttgcacg ccaacggtct acccctgacc ctgttgctgt ggtgtcaatt gctccacctt 120 gtgtctgagg gtctttcaca ccattaatgt gtaagtggtc catgtgtcca cctgacgccc 180 aattagtcca tgtgtcatga atacccgttc cagatgtgcc cacgcggtca cgtactttat 240 tcagagcaat a 251 <210> 178 <211> 251 <212> DNA <213> Artificial Sequence <400> 178 gggtaagaag ttcacttgga actttgagca tatccaatca aacaacggaa ttaaaccagt 60 tacaaaaaac ccatttacct acaatgcacc tgtagcaaac aaagcttccg ttgttaaaac 120 atcgagatgg ctactcaagt ataaagactc agtagccaca agggaggtag tggataaggt 180 aacatggaca atgaaatcta aggaagtcct acacattcgt gcaggttcca agactagtta 240 caagtcatac g 251 <210> 179 <211> 251 <212> DNA <213> Artificial Sequence <400> 179 tagtattgaa ttatgatttc tcgaaagacc ccactattaa tggttggaca ggaaatggtg 60 cgactataga atattcaaac gggaacatgc gagtgttgtt taacgactca tcaactaaca 120 gaatagtcta ttatagcaat gacttattaa ccaactactt gccagcagga gttaaatatt 180 ccgtcacaat agacgcattc agcaacaata atgggttaat tagggtaggt aattttgacg 240 ctctcagtac a 251 <210> 180 <211> 251 <212> DNA <213> Artificial Sequence <400> 180 ctgtacatat caaaaggctc gtccatgggt tcaaaccgtt catgtttcgt attaacgttt 60 ctcatacttt gtaccacctt tgacagtcgt aagctcagta attgacttac tttgtgcctc 120 cattatggcg actaagtatt tgcgctctac actataacgc acatttaaca tcaatgaaat 180 tgccaaaata acacctagaa taattgtacc cattataaac acttcctttt ctaattatat 240 tctaataata c 251 <210> 181 <211> 251 <212> DNA <213> Artificial Sequence <400> 181 tcttacccta ttttggaaac aactaacgcg gtaatgaaca cagtagctga gttagtagaa 60 aaccctaaat tggcagaacc aacattcaaa aatgtagaat ggaaggtaga aacacaccgc 120 ggagatagtc caatgtctaa cgaagcaatt caagactctg accctgactt agttgcgttg 180 attgctcgcc acttaacacg tattgggttg aacacaatca ataaagcagt aatgactgag 240 ttactagcta a 251 <210> 182 <211> 251 <212> DNA <213> Artificial Sequence <400> 182 tagtattgaa gtatgatttc tcgaaagacc ccactattaa gggttggaca ggaaatggtg 60 cgactataga atattcaaac gggaacatgc gagtgttgtt taacgactca tcaactaaca 120 gaagagtata ttatagcaat gacttattaa ccaactactt gccagcagga gttaaatatt 180 ccgtcacaat agacgcattc agcaacaata atgggttaat tagggtaggt aattttgacg 240 ctctcagtac a 251 <210> 183 <211> 251 <212> DNA <213> Artificial Sequence <400> 183 caattcctga ctctagaatg tcaaacccca cagcgtgtgc gtgcagtaca ttgtaagcaa 60 acattagacg agcgtgtatc ataatgtcta attctttagg ctcgtccata atgcgggcac 120 gcacttcttc taaaacattg tctaactccg cgtcatgtaa ttctaatacc tctgctaatt 180 ttgtcatatt atttttcctc ctcatagtct aatacctcaa tttggttatc atatacccac 240 cataggtgac c 251 <210> 184 <211> 251 <212> DNA <213> Artificial Sequence <400> 184 cgtatgactt gtaactagtc ttggaacctg cacgaatgtg taggacttcc ttagatttca 60 ttgtccatgt taccttatcc actacctccc ttgtggctac tgagtcttta tacttgagta 120 gccctctcga tgttttaaca acggaagctt tgtttgctac aggtgcattg taggtaaatg 180 ggttttttgt aactggttta attccgttgt ttgattggat atgctcaaag ttccaagtga 240 acttcttacc c 251 <210> 185 <211> 251 <212> DNA <213> Artificial Sequence <400> 185 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct atagacaata ttccaaacag gggtattgtg 120 aaagttcgtc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtatttg ttatgaccct gcacagtctc 240 aattaattac c 251 <210> 186 <211> 251 <212> DNA <213> Artificial Sequence <400> 186 gtattattag aatataatta gaaaaggaag tgtttataat gggtacaatt attctaggtg 60 ttattttggc aatttcattg atgttaaatg tgcgttatag tgtagagcgc aaatacttag 120 tcgacataat ggaggcacaa agtaagtcaa ttactgagct tacgactgtc aaaggtggta 180 caaagtatga gaaacgttaa tacgaaacat gaacggtttg aacccatgga cgagcctttt 240 gatatgtaca g 251 <210> 187 <211> 250 <212> DNA <213> Artificial Sequence <400> 187 tcaaaaggta aggcacccgt taacattata gtggaacacg gtaccactat tgacgtgagt 60 ggggtagagt gtacgttttt agacgatcct catgtggttc acaacgttgg cattctcgga 120 acctcaatcg gtcaaagttt tttatacgct acagacctaa tgactactgt ggcattcagt 180 gagtaccttg ataaaacagg taagaaaatt gatttgttac tcctagaggc taactatgac 240 ggtgctgtaa 250 <210> 188 <211> 250 <212> DNA <213> Artificial Sequence <400> 188 cggtcaaagt tttttatacg ctacagacct aatgactact gtggcattca gtgagtacct 60 tgataaaaca ggtaagaaaa ttgatttgtt actcctagag gctaactatg acggtgctgt 120 aagtggttat agtgaatata tgaaaattca cagcggttat gatacgtata ataatggttc 180 ctatagacat ttgtcagttc gccaaaatac agagttcgcc actaaatact tgtcagaggg 240 tggtacgagt 250 <210> 189 <211> 250 <212> DNA <213> Artificial Sequence <400> 189 tacgtctaac gaccctgcta gaccaaacct ctacatgggt tcatgggact acagcccttc 60 tgaggcgttt aaacctaagt gggctacaac attcgcacca aacgcatggt caggaccttc 120 ccttacaccg cctgtcaaag caccatcaac aggtttacga acaggagcct ttaaatttga 180 ggaacggata gacttcggta ctacgtcaga aaagaacgga cgttatgagt tggttatttt 240 gacagacgct 250 <210> 190 <211> 250 <212> DNA <213> Artificial Sequence <400> 190 cgtaaaattt cttttttaac ccgcttgcgt tcgttgtcta tgttgctaaa ctctttgcga 60 gcctgtgcga ggagtttttt atattccttg atgttgtcct ctgttacctc aacttgtttc 120 atttcgtgtg ctaacttggt aatgtcatca agtagtttat catattgcgc aaactcaata 180 gatggtacat cacctacgta aatcatcaac tcgttatcca ataattacac cgtcctcatt 240 tactgctaca 250 <210> 191 <211> 250 <212> DNA <213> Artificial Sequence <400> 191 tgctaacttg gtaatgtcat caagtagttt atcatattgc gcaaactcaa tagatggtac 60 atcacctacg taaatcatca actcgttatc aaatacttac accgtcctca tttacttcta 120 caccctcacc atatccacaa gttaggtccc taaccatttt agcggttgtt atgtacaatt 180 ttagacgcgg tttatcagtg acaatctgtc taaaccttgt gcgacctctg tccacatcat 240 aaatcggtga 250 <210> 192 <211> 250 <212> DNA <213> Artificial Sequence <400> 192 gtctgttaag tgtacgctta ctacatcatt cgtaaaatca gtaattttaa tcactgtttt 60 atctttatat aacctagcga cactcaaggt agcaccatgt ttatctttca aactatattc 120 aattccctca ttaacatagt cacgttcaaa acggtcatag tagaaccatt catcaatacc 180 atcaacctgc acgaaaaggc tgcctactcc aacaatggta tatcgtttac ctttttccaa 240 tatatcttct 250 <210> 193 <211> 250 <212> DNA <213> Artificial Sequence <400> 193 ttctgatagt tgatgagtcg ttaacccaca ctcgcatctt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctcaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 cagctgtgtg taaaaatgga ttttgaccat cctgtacgtt tgcaatactc aatggctttg 240 actctaatgc 250 <210> 194 <211> 250 <212> DNA <213> Artificial Sequence <400> 194 tacgtctaac gaccctgcta gaccaaacct ctacatgggt tcatgggact acagcccttc 60 tgaggcgttt aaacctaagt gggctacaac attcgcacca aacgcatggt caggaccttc 120 ccgtacaacg cctgtcaaag caccatcaac aggtttacga acaggagcct ttaaatttga 180 ggaacggata gacttcggta ctacgtcaga aaagaacgga cgttatgagt tggttatttt 240 gacagacgct 250 <210> 195 <211> 250 <212> DNA <213> Artificial Sequence <400> 195 ccttgacaaa actcaaggcg gtgcaattga ggcaacaatc agtggacgag gagcggaggc 60 tactacagac tacgcgtcaa acgttccgtt tttcgtatct gctaaaggta caggtgaaac 120 aaccgtatca ttgaatgttg tcgacttaca agcgggtgga gcatatagtg ctgttttagg 180 tattaccgca gacgaaaatg gtattatgac agtggggcag gacactcaag ctccttatgt 240 ctctgttact 250 <210> 196 <211> 250 <212> DNA <213> Artificial Sequence <400> 196 agaagatata ttggaaaaag gtaaacgata taccattgtt ggagtaggca gccttttcgt 60 gcaggttgat ggtattgatg aatggttcta ctatgaccgt tttgaacgtg actatgttaa 120 tgagggactt gaatatagtt tgaaagataa acatggtgct accttgagtg tcgctaggtt 180 atataaagat aaaacagtga ttaaaattac tgattttacg aatgatgtag taagcgtaca 240 cttaacagac 250 <210> 197 <211> 250 <212> DNA <213> Artificial Sequence <400> 197 tacgtctaac gaccctgcta gaccaaacct ctacatgggt tcatgggact acagcccttc 60 tgaggcgttt aaacctaagt gggctacaac attcgcacca aacgcatggt caggaccttc 120 ccgtacaccg cctgtcaaag caccatcaac aggtttacga acaggagcct ttaaatttga 180 ggaacggata gacttcggta ctacgtcaga aaagaacgga cgttatgagt tggttatttt 240 gacagacgct 250 <210> 198 <211> 249 <212> DNA <213> Artificial Sequence <400> 198 cgtccgcgca ttttatgacc atcaatcagg taacttatta ggacgaacaa agacaggtac 60 cctacaatta aacacagacg acagcggttt aaagttccgt ctacaattac caaataccca 120 attaggtcga gacgtctatg agttagtaaa acgcggtgac ctatcacagt gttcgtttgg 180 gtttatggtt aaaagtgata cgtggtcata caacgcaaac acagacacat atcaccgcac 240 aattgacca 249 <210> 199 <211> 249 <212> DNA <213> Artificial Sequence <400> 199 cattacaccg ttgacgttaa cattttcatg ccctgagggt gtggcacact ctattttaag 60 tgacccattt agaaacacac aaagtacatc tacaaacatg ctagtagata gtgaatttca 120 atctaaaaca tattggtctg atactactac tgtattggaa acgcagagaa acggttctaa 180 tgtattgtca ttagactttt cagatgaaca aattgaggac atgggtctag tggttcatga 240 ttttgtttc 249 <210> 200 <211> 249 <212> DNA <213> Artificial Sequence <400> 200 ctgttgacat tatggatgtc tcacaaaatt aacccttgca taagcgaggg ttttattata 60 tactagtgaa cgagggggat gaaattaatg aacactattt tcacaccaac taagcaacaa 120 aaagagaccg cgcgtaccat gtttgaactt tggaaaacat tagaaggtaa cgccatgagt 180 tatgacccca tgacaggggg aataaaagag gttgttgtta cagagaacat tgaaacacaa 240 tctaaaaaa 249 <210> 201 <211> 249 <212> DNA <213> Artificial Sequence <400> 201 attaattgtg cgtgttacct actatgatag tacgcgcgaa gatggaaaag tctcaatcac 60 aaacacaagt acagacaact gggtgcggta ttctgctagt ataactaccc aaaataaagc 120 actcaataag atagaagtgc tgtttgttat agacccttcg tttgtaggta cgttttacgt 180 aaaaaacttt aaactagaac aaaatgacca tgctaccccg ttcatccaac acattacaga 240 acgtggtaa 249 <210> 202 <211> 249 <212> DNA <213> Artificial Sequence <400> 202 aaaatattca ctggactatt cacaggtgat tttaaactca tgtgggatgg tgtcaaacaa 60 ctattctcag gagcaatcaa ggctatctgg aactggttac aaattctatt ctttgctaaa 120 atcataatag gagtcaaagg acttgcctct ggttttggta atacaatcag tggtatgtgg 180 acaagtgtca aaaacttttt cactacagga acaagtaacg catggaacct tgtaaaaggt 240 tgggcgtca 249 <210> 203 <211> 249 <212> DNA <213> Artificial Sequence <400> 203 tctctttctc aattaatact ttctctgtag gtgtcaattc gttttcaggt agttcgtaca 60 agactgcccc aattggtaaa ggtgtcgtct cgttgtttac taactcatat gttttcaaac 120 tcattcatcc tctagattat caattatatt ctcaactaca tttaataagt cctcgttatc 180 aacattttgc tgtactacgt taagcgcgta tagtgctaat tcagtaggtg agtcaccgtc 240 aattaatac 249 <210> 204 <211> 249 <212> DNA <213> Artificial Sequence <400> 204 cttcacaact tatctcacgt gttcccgcca atgggttgtg tgtgaagtcc atgatagtaa 60 gacaggcact atctccgtta tgtcgtctat aaattagata attacccaac tgcgccattt 120 cattaacttt aactaactgc tcttgtgatt catcaaaatg taatacccct gtgaactcta 180 taatgtcatc tgtttcatag ttgattatct catggtcatc tgacatttta atgagtcctg 240 ctccatctg 249 <210> 205 <211> 249 <212> DNA <213> Artificial Sequence <400> 205 cttcacaact tatctcacgt gttcccgcca atgggttgtg tgtgaagtcc atgatagtaa 60 gacaggcact atctccgtta tgtcgtctat aaattagata attacccaac tgcgccattt 120 ctttaacatt aactaactgc tcttgtgatt catcaaaatg taatacccct gtgaactcta 180 taatgtcatc tgtttcatag ttgattatct catggtcatc tgacatttta atgagtcctg 240 ctccatctg 249 <210> 206 <211> 249 <212> DNA <213> Artificial Sequence <400> 206 attaattgtg cgtgttacct actatgatag tacgcgcgaa gatggaaaag tctcaatcac 60 aaacacaagt acagacaact gggtgcggta ttctgctagt ataactaccc aaaataaagc 120 aatcaatcag atagaagtgc tgtttgttat agacccttcg tttgtaggta cgttttacgt 180 aaaaaacttt aaactagaac aaaatgacca tgctaccccg ttcatccaac acattacaga 240 acgtggtaa 249 <210> 207 <211> 249 <212> DNA <213> Artificial Sequence <400> 207 ctgttgacat tatggatgtc tcacaaaatt aacccttgca taagcgaggg ttttattata 60 tactagtgaa cgagggggat gaaattaatg aacactattt tcacaccaac taagcaacaa 120 acagagaacg cgcgtaccat gtttgaactt tggaaaacat tagaaggtaa cgccatgagt 180 tatgacccca tgacaggggg aataaaagag gttgttgtta cagagaacat tgaaacacaa 240 tctaaaaaa 249 <210> 208 <211> 249 <212> DNA <213> Artificial Sequence <400> 208 ttcatatagt gttattatac catttatgtg taaaacgttg ttatactagc tcatacgcaa 60 catcaaggtt acctaaatca tttttagcaa tcttaacaat aacaaactca tcctcaactt 120 cctcctgttc cccatccacg cgtatagtca ctttcttttc tatttcttgc tcctgtaaac 180 gcattccctc agcgcgtact ttctcatatt gctgtactgc ctccattagg tctaaaccgt 240 tgtttgcat 249 <210> 209 <211> 249 <212> DNA <213> Artificial Sequence <400> 209 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 tgagtaattc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgctcctct tttgttaaat gactattatc ttgtgcgctg 240 attagtttt 249 <210> 210 <211> 249 <212> DNA <213> Artificial Sequence <400> 210 acccctctgg tgtaccacct aatgctcgta ttgctgtagt taactcataa atgttacctg 60 tagttacgat tgaatctacg tcacgcccaa cacgtagagt aatatctttc tcgtccccca 120 tatcctcgac aatgttcatt gttttacttt ttaactgcat gttttcaaac tcaaagtcaa 180 tggtaaactt agcgcctcca aagtctgaaa taatactcct tagacgctcc actgctgttg 240 tctcattat 249 <210> 211 <211> 249 <212> DNA <213> Artificial Sequence <400> 211 tagtgttatt ataccattta tgtgtaaaac gttgttatac tagctcatac gcaacatcaa 60 ggttacctaa atcattttta gcaatcttaa caataacaaa ctcatcctca acttcatcct 120 gttccccctc cacgcgtata gtcactttct tttctatttc ttgctcctgt aaacgcattc 180 cctcagcgcg tactttctca tattgctgta ctgcctccat taggtctaaa ccgttgtttg 240 catatacag 249 <210> 212 <211> 249 <212> DNA <213> Artificial Sequence <400> 212 gagacgtcta tgagttagta aaacgcggtg acctatcaca gtgttcgttt gggtttatgg 60 ttaaaagtga tacgtggtca tacaacgcaa acacagacac atatcaccgc acaattgacc 120 acattggtag attggtagag atttcactag tttcaattcc cgcatatgat gatacaactg 180 tagcagtggc acaacggtca caaaaagcgt ttaaagaaca aaaaagaaaa ttagaattag 240 aacttgaca 249 <210> 213 <211> 249 <212> DNA <213> Artificial Sequence <400> 213 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 tgagtaagtc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgctcctct tttgttaaat gactattatc ttgtgcgctg 240 attagtttt 249 <210> 214 <211> 249 <212> DNA <213> Artificial Sequence <400> 214 cagatggagc aggactcatt aaaatgtcag atgaccatga gataatcaac tatgaaacag 60 atgacattat agagttcaca ggggtattac attttgatga atcacaagag cagttagtta 120 atgttaatga aatggcgcag ttgggtaatt atctaattta tagacgacat aacggagata 180 gtgcctgtct tactatcatg gacttcacac acaacccatt ggcgggaaca cgtgagataa 240 gttgtgaag 249 <210> 215 <211> 249 <212> DNA <213> Artificial Sequence <400> 215 ttttttagat tgtgtttcaa tgttctctgt aacaacaacc tcttttattc cccctgtcat 60 ggggtcataa ctcatggcgt taccttctaa tgttttccaa agttcaaaca tggtacgcgc 120 ggtctctgtt tgttgcttag ttggtgtgaa aatagtgttc attaatttca tccccctcgt 180 tcactagtat ataataaaac cctcgcttat gcaagggtta attttgtgag acatccataa 240 tgtcaacag 249 <210> 216 <211> 249 <212> DNA <213> Artificial Sequence <400> 216 gaaacaaaat catgaaccac tagacccatg tcctcaattt gttcatctga aaagtctaat 60 gacaatacat tagaaccgtt tctctgcgtt tccaatacag tagtagtatc agaccaatat 120 gatttagatt gaaattcact atctactagc atgtttgtag atgtactttg tgtgtttcta 180 aatgggtcac ttaaaataga gtgtgccaca ccctcagggc atgaaaatgt taacgtcaac 240 ggtgtaatg 249 <210> 217 <211> 249 <212> DNA <213> Artificial Sequence <400> 217 cgtactttct gcctaaacaa cagtacactc atataggcgt cattatattc tgttaatcta 60 acatgttcaa ccttaaacat taaaatacct cctcaggttg taagtaaacg tcaaaaacct 120 cctccataat cgtgtgtttg cctaaatgct tcttaatcgt ctcaaaccaa ttcttttcta 180 aatcactgtc aaggtcatca tgtgcaagct taaacccact cacgtacaca cgtggacccg 240 ctacagtat 249 <210> 218 <211> 249 <212> DNA <213> Artificial Sequence <400> 218 tagtgttatt ataccattta tgtgtaaaac gttgttatac tagctcatac gcaacatcaa 60 ggttacctaa atcattttta gcaatcttaa caataacaaa ctcatcctca acttcatcct 120 ggtccccctc cacgcgtata gtcactttct tttctatttc ttgctcctgt aaacgcattc 180 cctcagcgcg tactttctca tattgctgta ctgcctccat taggtctaaa ccgttgtttg 240 catatacag 249 <210> 219 <211> 249 <212> DNA <213> Artificial Sequence <400> 219 atgcaaacaa cggtttagac ctaatggagg cagtacagca atatgagaaa gtacgcgctg 60 agggaatgcg tttacaggag caagaaatag aaaagaaagt gactatacgc gtggatgggg 120 accaggagga agttgaggat gagtttgtta ttgttaagat tgctaaaaat gatttaggta 180 accttgatgt tgcgtatgag ctagtataac aacgttttac acataaatgg tataataaca 240 ctatatgaa 249 <210> 220 <211> 249 <212> DNA <213> Artificial Sequence <400> 220 ataatgagac aacagcagtg gagcgtctaa ggagtattat ttcagacttt ggaggcgcta 60 agtttaccat tgactttgag tttgaaaaca tgcagttaaa aagtaaaaca atgaacattg 120 tcgaggagat gggggacgag aaagatatta ctctacgtgt tgggcgtgac gtagattcaa 180 tcgtaactac aggtaacatt tatgagttaa ctacagcaat acgagcatta ggtggtacac 240 cagaggggt 249 <210> 221 <211> 249 <212> DNA <213> Artificial Sequence <400> 221 attaattgtg cgtgttacct actatgatag tacgcgcgaa gatggaaaag tctcaatcac 60 aaacacaagt acagacaact gggtgcggta ttctgctagt ataactaccc aaaataaagc 120 actcaatcag atagaagtgc tgtttgttat agacccttcg tttgtaggta cgttttacgt 180 aaaaaacttt aaactagaac aaaatgacca tgctaccccg ttcatccaac acattacaga 240 acgtggtaa 249 <210> 222 <211> 248 <212> DNA <213> Artificial Sequence <400> 222 tgactgtcat caactttttt aattagaatt atgttataat agaatgagaa cattatgagg 60 aggttataag atggcacagc ctgtcttttt acgaaacttt acattaaatg gtgtagatat 120 tggtgaggta tttgtggtag gtactgtaac aattccattc ctaaatgtag aacgcggata 180 ttatcaagtg ggtaattcag acggtcagaa cctacaatat acaagaatag gcaataacac 240 gcttactt 248 <210> 223 <211> 248 <212> DNA <213> Artificial Sequence <400> 223 tgttgcttag ggttcgtgca tattgcctta atacgcgaac gtttaccctc attgtacata 60 tagtccctca tgtcctcttt taccatttta cgcgttattc tacttctatc atctgtgttg 120 tatctgtgtg ctagaagaat accgtccgtg aagagtttca attcaacaag gtcaccctca 180 ttacccgtgt gctcaaatag tccactatta aaggctaaat caataacagg tgttttacta 240 cgtactag 248 <210> 224 <211> 248 <212> DNA <213> Artificial Sequence <400> 224 aagtaagcgt gttattgcct attcttgtat attgtaggtt ctgaccgtct gaattaccca 60 cttgataata tccgcgttct acatttagga atggaattgt tacagtacct accacaaata 120 actcacctat atctacacca tttaatgtaa agtttcgtaa aaagacaggc tgtgccatct 180 tataacctcc tcataatgtt ctcattctat tataacataa ttctaattaa aaaagttgat 240 gacagtca 248 <210> 225 <211> 248 <212> DNA <213> Artificial Sequence <400> 225 ttacctttta caaagtttgg cactggttga cccgtttggt atttagttgc tttggcgcgt 60 acttttactt tactacctac agggaaatca cgtgtgtctg tgatttttgg tttagacggt 120 ggtggttttg gtttaggttt gttgtcagta ttggaactat ttccaccaaa cccattttta 180 atgtctttag caaactgctc tttactaatt ccccatttac gcaagtatgg ataggggtca 240 atatggtc 248 <210> 226 <211> 248 <212> DNA <213> Artificial Sequence <400> 226 attagagtca aagccattga gtattgcaaa cgtacaggat ggtcaaaatc catttttaca 60 cacagcttac gcatggagta gtgatggaaa agagaggttc acactccaat acccaaatga 120 taatttatta ttgaattatg atttctcgaa agaccccact attaatggtt ggacaggaaa 180 tggtgcgact atagaatatt caaacgggaa catgcgagtg ttgtttaacg actcatcaac 240 taacagaa 248 <210> 227 <211> 248 <212> DNA <213> Artificial Sequence <400> 227 aagtaagcgt gttattgcct attcttgtat attgtaggtt ctgaccgtct gaattaccca 60 cttgataata tccgcgttct acatttagga atggaattgt tacagtacct accacaaata 120 cctcacctat atctacacca tttaatgtaa agtttcgtaa aaagacaggc tgtgccatct 180 tataacctcc tcataatgtt ctcattctat tataacataa ttctaattaa aaaagttgat 240 gacagtca 248 <210> 228 <211> 248 <212> DNA <213> Artificial Sequence <400> 228 ttacctttta caaagtttgg cactggttga cccgtttggt atttagttgc tttggcgcgt 60 acttttactt tactacctac agggaaatca cgtgtgtctg tgatttttgg tttagacggt 120 ggtggttgtg gtttaggttt gttgtcagta ttggaactat ttccaccaaa cccattttta 180 atgtctttag caaactgctc tttactaatt ccccatttac gcaagtatgg ataggggtca 240 atatggtc 248 <210> 229 <211> 247 <212> DNA <213> Artificial Sequence <400> 229 tagtaacgca ctattaaact caccttttgt gttaaatgcg cggttagatg ggagttctgt 60 gtacattttt ccaaacaatg gtgagcctat gattttggtc attagaatag actttccatt 120 tcctccggtg cgtgtaccgc gtgagacaac aatttgagca tgaacagcct caggtttgtt 180 ctcatagacg catgacccta tgaactcaca taatgctttt tcacttagtg ggtcagtaaa 240 gaagttg 247 <210> 230 <211> 247 <212> DNA <213> Artificial Sequence <400> 230 tggtgcgaat gttgtagccc acttaggttt aaacgcctca gaagggctgt agtcccatga 60 acccatgtag aggtttggtc tagcagggtc gttagacgta tttgggtact gtgatacgtg 120 cccactagtg acggtgaaac cagttggcaa tttcgtacct ctgtagtttt catttagacc 180 aatttcgtct ttaattggct ctgtagcgtc tttgttttct tcattgccaa actgtaggac 240 tttaccg 247 <210> 231 <211> 247 <212> DNA <213> Artificial Sequence <400> 231 tacgtggctt ctgttaagga gtttctaaag actgtacctg ttaccaatta tggaacgtgg 60 aaaagttacc caatctttga aatcaccaac gcagaagaaa acggtatgat tgctgttatg 120 aacgaaaccg gtaaagtcct acagtttggc aatgaagaaa acaaagacgc tacagagcca 180 attaaagacg aaattggtct aaatgaaaac tacagaggta cgaaattgcc aactggtttc 240 accgtca 247 <210> 232 <211> 247 <212> DNA <213> Artificial Sequence <400> 232 atttacaaaa gagtcaaacg atttaattat gattgataaa caagttaacc gcaacaagat 60 tgaccctctt gacgcgctta taaacgcgta cagtgaagca tacttttatg agttcgagga 120 aataaacggg tcagaacgtt acgcaagcgg tgattttggt tttggactgt aataaacgaa 180 cgaggcaacc caactagggt tgtctttttc gtgttataat ttataaagaa gttataattg 240 gaggagg 247 <210> 233 <211> 247 <212> DNA <213> Artificial Sequence <400> 233 aaatatataa ttcgttccat ggtgaacctc ctccaattat aacttcttta taaattataa 60 cacgaaaaag acaaccctag ttgggttgcc tcgttcgttt attacagtcc aaaaccaaaa 120 tcaccgcgtg cgtaacgttc tgaccagttt atttcctcga actcataaaa gtatgcttca 180 ctgtacgcgt ttataagcgc gtcaagaggg tcaatcttgt tgcggttaac ttgtttatca 240 atcataa 247 <210> 234 <211> 247 <212> DNA <213> Artificial Sequence <400> 234 acaacgccag ttggacagta aagaggggta atacccctct ttttttgtgc gctatatgat 60 ataatattaa tagaacataa catattagga ggaattataa tgattaaatt agaactaaaa 120 gtaaaagtta aaaaacaaac atttacagcg gagaaagtaa ctgtacgaac aatgcgcgag 180 attttagcat actacagtaa aatggaaaag gttgaaaaag gtgagttaca aatgaatgag 240 attgagg 247 <210> 235 <211> 247 <212> DNA <213> Artificial Sequence <400> 235 ggtcagaacg ttacgcaagc ggtgattttg gttttggact gtaataaacg aacgaggcaa 60 cccaactagg gttgtctttt tcgtgttata atttataaag aagttataat tggaggaggg 120 tcaccatgga acgaattata tatttaccta tgattatgta tatactagcg tgtgttttta 180 tggctattgg tgcctttttg gtagatataa ccgtaggttt tatggtatta ggtggcgctt 240 gtttggc 247 <210> 236 <211> 247 <212> DNA <213> Artificial Sequence <400> 236 ttatgattga taaacaagtt aaccgcaaca agattgaccc tcttgacgcg cttataaacg 60 cgtacagtga agcatacttt tatgagttcg aggaaataaa ctggtcagaa cgttacgcac 120 gcggtgagtt tggttttgga ctgtaataaa cgaacgaggc aacccaacta gggttgtctt 180 tttcgtgtta taatttataa agaagttata attggaggag gttcaccatg gaacgaatta 240 tatattt 247 <210> 237 <211> 246 <212> DNA <213> Artificial Sequence <400> 237 ctctaataat ctacagaaca ataatatgta tatacatttg attgtcctgc atttactgtg 60 attgtttttc ctgttgctgt ccatgatgtg tctaatacgt ttgaggcgtc atatctacgc 120 catacaatcg aagtaaaatt atcagtaatg tcatccttgc ctttgacaac tttagctgat 180 atactgattg taccctcacc atttacaaaa aactgtttag acggtgtaat aattacctca 240 gacgga 246 <210> 238 <211> 246 <212> DNA <213> Artificial Sequence <400> 238 aatactttaa atgaaagtcc tatatcaatc atcattttta taccattctg aaatgttaat 60 ttaaccgcgt tacctactga cccactgctt ataatcttat attcaatcat ctaatcaccc 120 ccaatcatac tctgtttgtt cttctgaatt gtcgttctct aggttccata atagtttacc 180 taatcgttgc gcctctagtt cctgttcatt atctagagca tgaccaattt tacagagcag 240 tgtgtg 246 <210> 239 <211> 246 <212> DNA <213> Artificial Sequence <400> 239 acctgcgatt ttcaattgag aaaaccattg ttctaacatt ccgttagaaa ttggagttcc 60 gctcattaaa taggtgtgtc ctgctttctt acttactttc atccaaaact tagttacgat 120 tgcgctcctg tttgctagac agtgagactc atcaaaaaca atcatagtgt ctttatctat 180 aaatttcaat aattcaggtg ttcgccatga tgattgaaag ctgattgata catattgcgt 240 tcctga 246 <210> 240 <211> 246 <212> DNA <213> Artificial Sequence <400> 240 cacacactgc tctgtaaaat tggtcatgct ctagataatg aacaggaact agaggcgcaa 60 cgattaggta aactattatg gaacctagag aacgacaatt cagaagaaca aacagagtct 120 gattgggtgt gattagatga ttgaatataa gattataagc agtgggtcag taggtaacgc 180 ggttaaatta acatttcaga atggtataaa aatgatgatt gatataggac tttcatttaa 240 agtatt 246 <210> 241 <211> 246 <212> DNA <213> Artificial Sequence <400> 241 ctaatgacat attaatgtct atagccatcc gtgactctga cgcaaaaggc aatgaagtga 60 ttgttgaata ctggtacggt aacaagttac taaaatctat caagacagac gtaactaagt 120 acaaatcctc ttggttccgc tgtacaatga cacgtgacca aacgggtaag aagttcactt 180 ggaactttga gcatatccaa tcaaacaacg gaattaaacc agttacaaaa aacccattta 240 cctaca 246 <210> 242 <211> 246 <212> DNA <213> Artificial Sequence <400> 242 tagagtcaaa gccattgagt attgcaaacg tacaggatgg tcaaaatcca tttttacaca 60 cagcttacgc atggagtagt gatggaaaag agaggttcac actccaatac ccaaatgata 120 atttagtctt gaatgatgat ttctcgaaag accccactat taatggttgg acaggaaatg 180 gtgcgactat agaatattca aacgggaaca tgcgagtgtt gtttaacgac tcatcaacta 240 acagaa 246 <210> 243 <211> 246 <212> DNA <213> Artificial Sequence <400> 243 cctatatgaa agagtatcat aatgtagagt tgcattatga tactaagtca gaagatattt 60 ttgttataag aaatgatatg ttcctatggg aataatgtct aataaggagg aaaaataatt 120 gattactgta acgattaata aatggcgaaa agcaaaagtg acacctgtta ttgttacagg 180 tacagtagaa ccgcctgtag gtaaggagga gttactcatt ggacgtgagg cattgcttga 240 cttaga 246 <210> 244 <211> 246 <212> DNA <213> Artificial Sequence <400> 244 gaaatttcac aatacccctg tttggaatat tgtctatagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aataaacact 120 tctttttcag ggataggaat aacccacgta acagcggtca agtcatttac tcgtgctagg 180 tctataccaa taaatacttc acgccctgtg atgtcaaact cctcgtctgt gtacgccttt 240 tcccac 246 <210> 245 <211> 246 <212> DNA <213> Artificial Sequence <400> 245 ttgagtagct catttaattc ctcagtgttt ctatatccca caatcgcatt ataagaccgt 60 ccacctaaat actgtttctc ttctatacag tagcgttctc taaaagattt ccacgttcca 120 gagtatacac ctgcgatttt caattgagaa aaccattgtt ctaacattcc gttagaaatt 180 ggagttccgc tcattaaata ggtgtgtcct gctttcttac ttactttcat ccaaaactta 240 gttacg 246 <210> 246 <211> 246 <212> DNA <213> Artificial Sequence <400> 246 taattgaaaa accagtgaac ggaattattg gcggtgcaaa ctgggtttta gaaaaactag 60 gcatggacaa gttaaaaaca tgggaggcac ctgaatacgc caaaggtaca ccaagtggcg 120 gtcacccggt agatggtccc atgactgtca atgatggacg tggtgctgaa atggttattg 180 acccaagtgg tcaagcggtt atccctaaag gtaagaacgt aacgatgtgg ggacgaaaag 240 gaaccc 246 <210> 247 <211> 246 <212> DNA <213> Artificial Sequence <400> 247 gaatactttt tcaactaatt tgcttgggtt agttgcgtag tcccaaacgt caccaacaac 60 actgctaacc ttatcaaacg cacttttagc catgtttttg gcaccgttcc agatgtttat 120 tacgcctcct gtaattttgt caaagaagcc agtacctttt ttgtatgcaa acttaggacg 180 tttatgacct aacacttgtg cagtttcttc tgctgttaaa acgtgggttc cttttcgtcc 240 ccacat 246 <210> 248 <211> 246 <212> DNA <213> Artificial Sequence <400> 248 aatactttaa atgaaagtcc tatatcaatc atcattttta taccattctg aaatgttaat 60 ttaaccgcgt tacctactga cccactgctt ataatcttat attcaatcat ctaatcaccc 120 ccaatcagac tctgtttgtt cttctgaatt gtcgttctct aggttccata atagtttacc 180 taatcgttgc gcctctagtt cctgttcatt atctagagca tgaccaattt tacagagcag 240 tgtgtg 246 <210> 249 <211> 245 <212> DNA <213> Artificial Sequence <400> 249 cctctgtctt tttagcccgt ttgtgttcta acatatgtgt gcgaacgtca ggtttttcaa 60 aaagagggtt agatttaaac cagttttcct cgtcatccgc ctcgtcaaaa ctatccattt 120 cccaccagag agctaagtag tgttcagcct ctacctcacc tgttaatact ttcatagtca 180 ttggatattc ctccatatga tagtgtccgt ttaggttttg tgaggttgta ctaatcatta 240 agtta 245 <210> 250 <211> 245 <212> DNA <213> Artificial Sequence <400> 250 gacgggcacc agacagctct tttttaatct ctctcacgtc ctctaaacgt gcgtcaatac 60 gctccatggt taattgcatt ttgataaagt tgtcctcatt cattggcatt cgttcccgct 120 cctaactgtg attgtatgct agtctattta tcattttact catgtagtca acttggttct 180 gtaacgtgtc tactgcgtta tcttgagtgc tatatccgtt tagttcataa atgaggtcgt 240 ccatg 245 <210> 251 <211> 245 <212> DNA <213> NCIMB 43666 node 183 <400> 251 agagacaaag ccagtgagta ttgcaaacgt acaggatggt caaaatccat ttttacacac 60 agcttacgca tggagtagtg atggaaaaga gaggttcaca ctccaatacc caaatgataa 120 tttagtagtg aattttgatt tctcgaaaga ccccactatt aatggttgga caggaactgg 180 tgcggctata gaatattcta tcgggaacat gcgagtgttg tttaacgact catcaactaa 240 cagaa 245 <210> 252 <211> 245 <212> DNA <213> Artificial Sequence <400> 252 acgcttgagg tattgattgc ccactctgtt ttagttgatt tgacagaggc gccattttgt 60 cccgttgttc tcatccacgt gtacttactt gggtccgtgc taggttcttg agtatagtta 120 ctatattcct gtagatggct caaccggtaa tggtgtgaaa tctatcgctg ttacttacgc 180 tgtaggtacc tcaggtacaa cagcaccatc cacaggttgg caagcaacac caccaaatgt 240 aacag 245 <210> 253 <211> 245 <212> DNA <213> Artificial Sequence <400> 253 tagacaatgc gtctaaagac ttttctatca cgtgttgagg tggttgtttg atagttccaa 60 actcaataaa gtgcgcgcgc cacgcaacct catcatcaaa gccaatttct acatatccat 120 ctttggcatt gctatagata acatggtctc tcatatgctc acccatatat gaaccacgct 180 taccgctcat ttttgcttta ctgttagacc agtatggtac gcgtttgcta aattcctcag 240 caacc 245 <210> 254 <211> 245 <212> DNA <213> Artificial Sequence <400> 254 tgattgtatg ctagtctatt tatcatttta ctcatgtagt caacttggtt ctgtaacgtg 60 tctactgcgt tatcttgagt gctatatccg tttagttcat aaatgaggtc gtccatgtct 120 aacgcgttgc catggaactc ctcctctaga actctgttaa acagcatatt taactcatca 180 tcaaacccat taccgtttaa taccttgtta atatactccg ttttaaattg ctctaacata 240 attat 245 <210> 255 <211> 245 <212> DNA <213> Artificial Sequence <400> 255 cgttttaaat gaggtggtaa aatgagtgat aattatgtag actttagtga catctacaaa 60 gcgcttggtg aactaggtaa agacttagac cgtgaggcaa ataaaataat gaacgacata 120 gcgcctgtgg ttgctgagga atttagcaaa cgcgtaccat actggtctaa cagtaaagca 180 aaaatgagcg gtaagcgtgg ttcatatatg ggtgagcata tgagagacca tgttatctat 240 agcaa 245 <210> 256 <211> 245 <212> DNA <213> Artificial Sequence <400> 256 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctcta 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg gggtctttcg agaaatcata 240 attca 245 <210> 257 <211> 245 <212> DNA <213> Artificial Sequence <400> 257 tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat ggtgcgacta 60 tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact aacagaatag 120 tctattagag caatgactta ttaaccaact acttgccagc aggagttaaa tattccgtca 180 caatagacgc attcagcaac aataatgggt taattagggt aggtaatttt gacgctctca 240 gtaca 245 <210> 258 <211> 245 <212> DNA <213> Artificial Sequence <400> 258 gtattgttga cactgctgtt ttagttaatt tagtggctcc tgctgttggt gtagccgtta 60 ctgcgtcaaa gattccccaa tactgtatac tattgtcctg tgaaccgttt aataggatat 120 ttggcgcgct aaaattgagg caactaatga gggtgctaca cagtggacag acggtaatac 180 acctacagta gacaatacta gccctacata tgtagggtat agtaccacgg acactgtacc 240 tgagg 245 <210> 259 <211> 244 <212> DNA <213> Artificial Sequence <400> 259 tgaccgctgt agcgcagacg ataccgtcac attaacatta ggtgattttc gtattcaata 60 ttcaggtatt gaccctcagt tgctacagat agcgtcagat ttttcaaaac agtttgacaa 120 cagtagtccg tctgaggtaa ttattacacc gtctaaacag ttttttgtaa atggtgaggg 180 tacaatcagt atatcagcta aagttgtcaa aggcagggat gtcattactg ataattttac 240 ttcg 244 <210> 260 <211> 244 <212> DNA <213> Artificial Sequence <400> 260 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccgtcc 120 ttagtaattc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgctcctct tttgttaaat gactattatc ttgtgcgctg 240 atta 244 <210> 261 <211> 244 <212> DNA <213> Artificial Sequence <400> 261 ggtactttta ttacagggca atcactagac gagattgaac atttaaaaaa ttctgacatt 60 tacacagcaa caaacattat cagtggcgat attgctaaat gtttgattag agagcgaccg 120 gatggaagtg taagtaaacc tcagattgta aatatcttgc gtagtaaacc agatacaaac 180 ctaacgtcct acggttggtt gtatgctatt accatgtata cccttttata tgggtctgcg 240 tttg 244 <210> 262 <211> 244 <212> DNA <213> Artificial Sequence <400> 262 tgagttaaaa gatgggttct ataatttagg taagcctgaa attgcaggca aggttgatga 60 agttccaccg cgtcccaata aaccaagcgg gaaacaatat ttagtaattt atgatagtga 120 ggtatttgag caagattttg tcatttgtgc taaagatttg tttagtggta aacgttggga 180 aattgtcaat gacctagaca aggcgcgtaa atggtattta gaagtacgtg acagtctatt 240 tact 244 <210> 263 <211> 244 <212> DNA <213> Artificial Sequence <400> 263 tagtacaacc tcacaaaacc taaacggaca ctatcatatg gaggaatatc caatgactat 60 gaaagtatta acaggtgagg tagaggctga acactactta gctctatggt gggaaaggga 120 tagttttgac gaggcggatg acgaggaaaa ctggtttaaa tctaaccctc tttttgaaaa 180 acctgacgtt cgcacacata tgttagaaca caaacgggct aaaaagacag agggagaggc 240 taaa 244 <210> 264 <211> 244 <212> DNA <213> Artificial Sequence <400> 264 gttttgtagg taatatccac tgacccatcc tgaggcaggt attttcttac ctgagttctt 60 agttacataa taccattggt tgtttttaat aatcttttga cccgtttgac gtttgggtgt 120 ttcaaacgtg acgcccttag gtaacagacc gtatgacttg taactagtct tggaacctgc 180 acgaatgtgt aggacttcct tagatttcat tgtccatgtt accttatcca ctacctccct 240 tgtg 244 <210> 265 <211> 244 <212> DNA <213> Artificial Sequence <400> 265 tctgtattag atgggttaga tgtttgttgc tccatctttg atgaaatggc tgagaataaa 60 gatacttcta ttgttgaggt tattgagtca tctcagtcac aacaattaca accccttaac 120 ttaatgaata gtacaacctc acaaaaccta aacggacact atcatatgga ggaatatcca 180 atgactatga aagtattaac aggtgaggta gaggctgaac actacttagc tctatggtgg 240 gaaa 244 <210> 266 <211> 244 <212> DNA <213> Artificial Sequence <400> 266 tcctatggga ataatgtcta ataaggagga aaaataaatg attactgtaa cgattaataa 60 atggcgaaaa gcaaaagtga cacctgttat tgttacaggt acagtagaac cgcctggagg 120 taaggaggag ttactcattg gacgtgaggc attgcttgac ttagaaacag atagcattta 180 cattgaggct agtgatttaa cttgggtatt ccctacagac attaatgata aacgttacgc 240 ttca 244 <210> 267 <211> 244 <212> DNA <213> Artificial Sequence <400> 267 taatcagcgc acaagataat agtcatttaa caaaagagga gcgtattgag cgcgagcaag 60 aagaacaaga gttatataat tatgaacaac tttcattaga cgatattcct gagggactta 120 ctaaggacgg gtggttgatt tacgaggacc ttgttccaca acttaaacag ctaccaattt 180 caaaactaga cgctggcatg ctagtcattt attgtaatac ttacgctatt tacagtcagg 240 caac 244 <210> 268 <211> 244 <212> DNA <213> Artificial Sequence <400> 268 tgtaagtaaa cctcagattg taaatatctt gcgtagtaaa ccagatacaa acctaacgtc 60 ctacggttgg ttgtatgcta ttaccatgta taccctttta tatgggtctg cgtttgaaat 120 cattagacgc aacggaacac aagttactaa gctacagatt gtcagccctc atacaattac 180 aatcttacaa gacacagcga gtaaagaatt gtcatatgag tacattgacc ctgacaatca 240 aaag 244 <210> 269 <211> 244 <212> DNA <213> Artificial Sequence <400> 269 tttagcagtt gcacgccaac ggtctacccc tgaccctgtt gctgtggtgt caattgctcc 60 accttgtgac tgagggtctt tcacaccatt aatgtgtaag tggtccatgt gtccacctga 120 cgcccaacct tttacaaggt tccatgcgtt acttgttcct gtagtgaaaa agtttttgac 180 acttgtccac ataccactga ttgtattacc aaaaccagag gcaactcatt tgactcctat 240 tatg 244 <210> 270 <211> 243 <212> DNA <213> Artificial Sequence <400> 270 tcatagttga ttatctcatg gtcatctgac attttaatga gtcctgctcc atctgtggac 60 gcaattccta tagggttaaa ttccctatca gtaaaataaa attctatttt aaaaaccccc 120 cttacacgtg tttctttatt aattatacca taaaaaagcc actctttggc gagtggctag 180 atgttattac aagtaggttc gttggttctt cacagttact tctaaagtgt ctgtagccca 240 atc 243 <210> 271 <211> 243 <212> DNA <213> Artificial Sequence <400> 271 gatatgttag tggataacgt agcctttgag gacttattac cattagtaca gggagtcttt 60 gaacaagtca acgggggtac agtttcaaag gagaaataac aggacttgag gaaaaaacct 120 ttgaggacca gttagaaacc cttgaggaaa catattcatc cctcttagaa agtagctggc 180 aactctcaga gatagagaac gctgactact ttcttttatt acaattgttt ggtaaagagt 240 cta 243 <210> 272 <211> 243 <212> DNA <213> Artificial Sequence <400> 272 ataatagacg aattaattct actagtagct tatagtcttt cataaactct tctttggttt 60 tgtgcgattc aatcaattca attgccgcat atccccacga gttccatccg ccacctacgt 120 cataaaatcc cgcgtttgtg cgtgctgttt gaattactcg cccgttacct actacgtgcg 180 agaagaaccc actgttgacg ggtctgcgca tatgatagtc tgcctcgttt tgcgctgtag 240 atg 243 <210> 273 <211> 243 <212> DNA <213> Artificial Sequence <400> 273 catatttcct actggttttc cgctttgcac catgtgttaa tcagctcctt ttttctctag 60 cttttcaagt tcctcaggac ttaagaaacg cttaataaag tcagcgccat ccatcacctt 120 ttcttgtata gactctttac caaacaattg taataaaaga aagtagtcag cgttctctat 180 ctctgagagt tgccagctac tttctaagag ggatgaatat gtttcctcaa gggtttctaa 240 ctg 243 <210> 274 <211> 243 <212> DNA <213> Artificial Sequence <400> 274 tgtttcttta ttaattatac cataaaaaag ccactctttg gcgagtggct agatgttatt 60 acaagtaggt tcgttggttc ttcacagtta cttctaaagt gtctgtagcc caatcggagt 120 taatgaactg taggaaatgt tctcctacat caagtgcgaa gccttcccac tgatttccta 180 tggttgctag gtcctcacgt tctacaccat ttacaaagaa ggttttatca tgtgtgttta 240 tga 243 <210> 275 <211> 243 <212> DNA <213> Artificial Sequence <400> 275 caataatggg ttaattaggg taggtaattt tgacgctctc agtacatggc aaacaataaa 60 acaaggtgac acaccttcaa cgtataaatt tgagggtata accgcagggg caactcatgc 120 ttttagtata cagggtaatt caaatgcttt aattataact ataacaaaaa taaaaatcga 180 actaggaaac acggcaacca tctacacccc aaacccatct gaagatttcg cgaacgcata 240 tcc 243 <210> 276 <211> 243 <212> DNA <213> Artificial Sequence <400> 276 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgtagc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgatata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg gggtctttcg agaaatcata 240 att 243 <210> 277 <211> 243 <212> DNA <213> Artificial Sequence <400> 277 ataatagacg aattaattct actagtagct tatagtcttt cataaactct tctttggttt 60 tgtgcgattc aatcaattca attgccgcat atccccacga gttccatccg ccaccaacgt 120 cataaaagcc cgcgtttgtg cgtgctgttt gaattactcg cccgttacct actacgtgcg 180 agaagaaccc actgttgacg ggtctgcgca tatgatagtc tgcctcgttt tgcgctgtag 240 atg 243 <210> 278 <211> 243 <212> DNA <213> Artificial Sequence <400> 278 acaaaagctt atacagacga atacaattat tgtattgtat ttagtttact taaaaagtct 60 gtggtaacat attggaaaaa taagacctac aatactcatg aaaatgtaga cttaagtaaa 120 tacaacgcat gggcttatga tgggcgctat acatgggtac gctatcaggc agataaaggt 180 acacgctaca tggctgtacg tgaccataaa acgggtgaag tatttgtaac atttagctaa 240 acg 243 <210> 279 <211> 243 <212> DNA <213> Artificial Sequence <400> 279 aattatgatt tctcgaaaga ccccactatt aatggttgga caggaaatgg tgcgactata 60 gaatattcaa acgggaacat gcgagtgttg tttaacgact catcaactaa cagaatagtc 120 tattatatca atgacttatt aaccaactac ttgccagcag gagttaaata ttccgtcaca 180 atatacgcat tcagcaacaa taatgggtta attagggtag gtaattttga cgctctcagt 240 aca 243 <210> 280 <211> 243 <212> DNA <213> Artificial Sequence <400> 280 tttttaaaca ctcctgtgct actgtactgt tttatattgt ttttgatttg tgagttctct 60 agtgtaattt cacctgagcc agttgagtta tctgaatatt tcacattgta agggtttctg 120 atggtacaac atcagtagcc tatacagtga actatattcc tgtagatggc tcaaccggta 180 atggtgtgaa atctatcgct gttacttacg ctgtaggtac ctcaggtaca acagcaccat 240 cca 243 <210> 281 <211> 243 <212> DNA <213> Artificial Sequence <400> 281 ataatagacg aattaattct actagtagct tatagtcttt cataaactct tctttggttt 60 tgtgcgattc aatcaattca attgccgcat atccccacga gttccatccg ccaccaacgt 120 cataaaatcc cgcgtttgtg cgtgctgttt gaattactcg cccgttacct actacgtgcg 180 agaagaaccc actgttgacg ggtctgcgca tatgatagtc tgcctcgttt tgcgctgtag 240 atg 243 <210> 282 <211> 242 <212> DNA <213> Artificial Sequence <400> 282 gatgaccttg acagtgattt agaaaagaat tggtttgaga cgattaagaa gcatttaggc 60 aaacacacga ttatggaaga ggtttttgac gtttacttac aacctgagga ggtattttaa 120 aggaggacta aagatgttag gttgtgatta ttgtaaattt gaaccaatga gggagacact 180 attttcctca gattacttat ggagtgggag gactgacatg actgaggtgt ttataaacgg 240 ga 242 <210> 283 <211> 242 <212> DNA <213> Artificial Sequence <400> 283 gagtagaaat acgctttcaa atggtacgta tacaaattgg gtagtaacta gctcatacac 60 gggtagagac tcaattttta ttagtgctac agctccaagt aacccaacta cagggacatt 120 atggcaataa cctaatgacc ctactgtgct aaaatggaac ggtacagcgt gggaaaactg 180 ggggatgtca attaataata ttgtatcaga caatgttatt gctgaaaacg ggatgtttaa 240 aa 242 <210> 284 <211> 242 <212> DNA <213> Artificial Sequence <400> 284 tacaccgtcc cacaagttac ctataacacg tatgaagttg tctttgatac ctgaaacgcc 60 ttttccaatg tttgacgccc aaccttttac aaggttccat gcgttacttg ttcctgtagt 120 gaaaaagatt ttgacacttg tccacatacc actgattgta ttaccaaaac cagaggcaag 180 tcctttgact ccttttatga ttttagcaaa gaatagaatt tgtaaccagt tccagatagc 240 ct 242 <210> 285 <211> 242 <212> DNA <213> Artificial Sequence <400> 285 ctgttttata ttgtttttga tttgagagat ctctagtgta agttcacctg agccagttga 60 gttatctgaa tatatcacat tgaaagggtt tctgatggta ctacctacaa actcaacccc 120 actaactatt taaaacaacc cgttttcagc aaaaacattg tctgatacaa tataattaat 180 tgacatcccc cagttttccc acgctgaacc gtaccatttt agcacagtag ggtcattagg 240 tt 242 <210> 286 <211> 242 <212> DNA <213> Artificial Sequence <400> 286 tcctcaggtt gtaagtaaac gtcaaaaacc tcctccaatc agcttaccac cgcacattgg 60 gcaatagtga atctcaaact gagcggtata accttggttg tcaacctcag ttgtgactgt 120 catagttgtc ccgtttataa acacctcagt catgtcagtc ctcccactcc ataagtaatc 180 tgaggaaaat agtgtctccc tcattggttc aaatttacaa taatcacaac ctaacatctt 240 ta 242 <210> 287 <211> 242 <212> DNA <213> Artificial Sequence <400> 287 tgttatcggg ttcattcaag gtatggttga cactgttatg ggtattataa aaatattcac 60 tggactattc acaggtgatt ttaaactcat gtgggatggt gtcaaacaac tattctcagg 120 agcaatctag gctatctgga actggttaca aattctattc tttgctaaaa tcataaaagg 180 agtcaaagga cttgcctctg gttttggtaa tacaatcagt ggtatgtgga caagtgtcaa 240 aa 242 <210> 288 <211> 242 <212> DNA <213> Artificial Sequence <400> 288 agtaaaagag tgtattccgt ttgctttacc ttttacgtca cagtctacta ctaataattt 60 gtttagttcc ccacataaga cccctttatt catgtttctt attttaccta atgttttgta 120 actctctaga gcttgccact cttttatcgc gggaatttta gtacgcgctt tgagaggaaa 180 ccccttaaat tggttgtatt tcattgtatc actccttaga acaaacgcat aagtatataa 240 ac 242 <210> 289 <211> 242 <212> DNA <213> Artificial Sequence <400> 289 gtttatatac ttatgcgttt gttctaagga gtgatacaat gaaatacaac caatttaagg 60 ggtttcctct caaagcgcgt actaaaattc ccgcgataaa agagtggcaa gctctagaga 120 gttacaatac attaggtaaa ataagaaaca tgaataaagg ggtcttatgt ggggaacaaa 180 acaaattatt agtagtagac tgtgacgtaa aaggtaaagc aaacggaata cactctttta 240 ct 242 <210> 290 <211> 241 <212> DNA <213> Artificial Sequence <400> 290 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taagtcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat cctgtacgtt tgcaatactc aatggctttg 240 a 241 <210> 291 <211> 241 <212> DNA <213> Artificial Sequence <400> 291 taataaagat ggcgtctctc agtcccaaat taaatgccac agtttcttct agtaaaatat 60 tcatggtgac ctctcctctt tacccctcat gtctctcatt aacaacataa tcaaagtcac 120 ttgcaaagag cggaatcatt agttctccat caacgtcaca gtgcaataga ggtgtacggt 180 attggtagtc aataaaaatg gtgtctgttt ccttatctac atatgcaaaa caacccgcgt 240 a 241 <210> 292 <211> 241 <212> DNA <213> Artificial Sequence <400> 292 tttccctctc aatttgtttc tattactgtt tggatgttct tgtttgttgt gacaagaaaa 60 acaaatactt tctaaataat tcatatctaa cctatgttcc catccctcag agggtcgtat 120 ctccgtggta tggtgcacca tgtctgcttt ggtagtgata tctttgctca tacatacttc 180 acagaatggt gtctctaata gttttgcttt acgtgttgct ctccattcag gtgtgtgata 240 g 241 <210> 293 <211> 241 <212> DNA <213> Artificial Sequence <400> 293 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct atagacaata ttccaaacag ggggattgtg 120 aaatttcttc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtatttg ttatgaccct gcacagtctc 240 a 241 <210> 294 <211> 241 <212> DNA <213> Artificial Sequence <400> 294 cttacttggg tccgtgctag gttcttgagt atagttacta gattgaccca tatatagcgg 60 atatgcgttc gcgaaatctt cagatgggtt tggggtgtag atggttgccg tgtttcctcg 120 ttcgattatt atgtttgtta tagttataat taaagcattt gaattaccct gtatactaaa 180 agcattagtt gcccctgcgg ttataccctc aaatttatac gttgaaggtg tgtcaccttg 240 t 241 <210> 295 <211> 241 <212> DNA <213> Artificial Sequence <400> 295 gtatgtgtta gtaaatgggg taaaattgcc tattaataca ttgtttggtg ccacaggtgc 60 agagtttaat gggttatatg acccacgttt tcaatttcta acatgtgtga ttgtgcaatt 120 aattatggct gacttctacg agggaattag ggaccatgtt accatgttac agagcaacac 180 agactgtcac gcctacattc ctcatgatga ggaggctgaa cgtattacag acgcgttctg 240 t 241 <210> 296 <211> 241 <212> DNA <213> Artificial Sequence <400> 296 gaaatttcac aatacccctg tttggaatat tgtctatagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aatcaacaat 120 tctttttcag ggataggaat aacccacgta acagcggtca agtcatttac tcgtgctagg 180 tctataccaa taaatacttc acgccctgtg atgtcaaact cctcgtctgt gtacgccttt 240 t 241 <210> 297 <211> 241 <212> DNA <213> Artificial Sequence <400> 297 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcttcaact 120 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt cggtaatttt 240 g 241 <210> 298 <211> 241 <212> DNA <213> Artificial Sequence <400> 298 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcttcaact 120 aacagaagag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt aggtaatttt 240 g 241 <210> 299 <211> 241 <212> DNA <213> Artificial Sequence <400> 299 tacgcgggtt gttttgcata tgtagataag gaaacagaca ccatttttat tgactaccaa 60 taccgtacac ctctattgca ctgtgacgtt gatggagaac taatgattcc gctctttgca 120 agtgactgtg attatgttgt taatgagaga catgaggggt aaagaggaga ggtcaccatg 180 aatattttac tagaagaaac tgtggcattt aatttgggac tgagagacgc catctttatt 240 a 241 <210> 300 <211> 241 <212> DNA <213> Artificial Sequence <400> 300 tgagactgtg cagggtcata acaaatacct tgtacgtcta aattgtttgt ctcaataaac 60 gccaaaaccc aatttaacat atcctcccaa tcacactgac cgtcaggacg ggacgaaatt 120 tcacaatccc cctgtttgga atattgtcta tagggtgttc tatcgttagc ctctttctga 180 acaataccac cacccgttgt tgctacccac gcgtgagagt caacaataaa caattctttt 240 t 241 <210> 301 <211> 240 <212> DNA <213> Artificial Sequence <400> 301 gtacttagtt gttttagttg ctttactgat tacagtattg gtttatatac ttatgcgttt 60 gttctaagga gtgatacaat gaaatacaac caatttaagg ggtttcctct caaagcgcgt 120 actaaaagtc ccgcgataaa agagtggcaa gctcaagaga gttacaaaac attaggtaaa 180 ataagaaaca tgaataaagg ggtcttatgt ggggaacaaa acaaattatt agtagtagac 240 <210> 302 <211> 240 <212> DNA <213> Artificial Sequence <400> 302 cctcaccact gatagtggct caatgtcctc ccaacgtgta aaatcaggtt tccaattcat 60 taagtaagaa acagcctccc tacctgtgcg tgtctcacgg agtttcaggc gtctcattgg 120 gttacctgtt ttagattgtg tttcaatgtt ctctgtaaca acaacctctt ttattccccc 180 tgtcatgggg tcataactca tggcgttacc ttctaatgtt ttccaaagtt caaacatggt 240 <210> 303 <211> 240 <212> DNA <213> Artificial Sequence <400> 303 caaagccatt gagtattgca aacgtacagg atggtcaaaa tccattttta cacacagctt 60 acgcatggag tagtgatgga aaagagaggt tcacactcca atacccaaat gataatttag 120 tattgaagta tgatttctcg aaagacccca ctattaatgg ttggacagga aatggtgcga 180 ctatagaata ttcaaacggg accatgcgag tgttgtttaa cgactcatca actaacagaa 240 <210> 304 <211> 240 <212> DNA <213> Artificial Sequence <400> 304 gtcctaatga acttgctaga gactttagtt gtttagatgt ttcattcata accttaaagg 60 cgcctgatgg tttccctttt tcgtcaagat aaccgtattc agatacctct tgagttgcct 120 gactgtatat agcgtaagta ttacaataaa tgactagcat gccagcgtct agttttgaaa 180 ttggtagctg tttaagttgt ggaacaaggt cctcgtaaat caaccaccct tccttagtaa 240 <210> 305 <211> 240 <212> DNA <213> Artificial Sequence <400> 305 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cagtgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg gggtctttcg agaaatcata 240 <210> 306 <211> 240 <212> DNA <213> Artificial Sequence <400> 306 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cagtgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagag gggtctttcg agaaatcata 240 <210> 307 <211> 240 <212> DNA <213> Artificial Sequence <400> 307 gtacttagtt gttttagttg ctttactgat tacagtattg gtttatatac ttatgcgttt 60 gttctaagga gtgatacaat gaaatacaac caatttaagg ggtttcctct cacagcgcgt 120 actaaaagtc ccgcgataaa agagtggcaa gctcaagaga gttacaaaac attaggtaaa 180 ataagaaaca tgaataaagg ggtcttatgt ggggaacaaa acaaattatt agtagtagac 240 <210> 308 <211> 240 <212> DNA <213> Artificial Sequence <400> 308 aagtaaacta aatacaatac aataattgta ttcgtctgta taagcttttg tgctacgtaa 60 cacaactctc ttgtctatca tataggcgcc atcaaaaact tgcttgtact caataacttc 120 ataatgagaa aagagttgaa aaaacacatt aagcagatga acccacaaga gattgtaact 180 gttgtgaata tggttgagag cgctacaaga ggaatgtgta aagagacaat taggactagt 240 <210> 309 <211> 239 <212> DNA <213> Artificial Sequence <400> 309 ttgacgcacg tttagaggac gtgagagaga ttaaaaaaga gctgtctggt gcccgtcaac 60 aaatcgcgga cctagccaaa cgtctttcgc agtcaatgga ccatgttaac acactagagg 120 acgccatcaa agagctagca tcacggaacc cctggcttac tagaacaacc gtaggagcaa 180 ttatcactgg tgtagtgggt gctattttgg cattcatcac tggttaaata tatgatata 239 <210> 310 <211> 239 <212> DNA <213> Artificial Sequence <400> 310 atgaaagact taggacatga aaccatacct aacaccctaa tggtctatac accgtcagga 60 ggcatacact attattttac gttaccagat gacgcactag acctacgcaa acaacctaga 120 gaggactgag gtatagattt tcagatgaat gggtcctttg tggtagcagt agggtcagag 180 ttagaaaacg ggacatatag cgtggtttcc aataaaccaa tcgcacaagc acccagaga 239 <210> 311 <211> 239 <212> DNA <213> Artificial Sequence <400> 311 tgtaggtaaa tgggtttttt gtaactggtt taattccgtt gtttgattgg atatgctcaa 60 agttccaagt gaacttctta cccgtttggt cacgtgtcat tgtacagcgg acccaagatg 120 atttgtactt agttacgtct gtcttgatag attttagtaa cttgttaccg taccagtatt 180 caacaatcac ttcattgcct tttgcgtcag agtcacggat ggctatagac attaatatg 239 <210> 312 <211> 239 <212> DNA <213> Artificial Sequence <400> 312 atttaatatc ccgtaactca ggtgctttta cagaaccgtg tgagcgtaca tattcaccga 60 acgcacgaac ctcagcttca gcaacgtttt ctgtagggtt gattttcttt acattttcca 120 tacttctcgc ctctcctttt tctaatttgt ccacgtcttc ctctaatgct ttagcacgtt 180 ccgcgtccac agatttatct ttattttctt ctggttcaac ctcgtctgcc tcatcatcc 239 <210> 313 <211> 239 <212> DNA <213> Artificial Sequence <400> 313 tgttaacatg gtcaattgac tgcgaaagac gtttgtctag gtccgcgatt tgttgacggg 60 caccagacag ctctttttta atctctctca cgtcctctaa acgtgcgtca agacgctcca 120 tggttaattg cattttgata aagttgtcct cattcattgg cattcgttcc cgctcctaac 180 tttgattgta tgctagtcta tttatcattt tactcatgta gtcaacttgg ttctgtaac 239 <210> 314 <211> 239 <212> DNA <213> Artificial Sequence <400> 314 accattttac gcgttattct acttctatca tctgtgttgt atctgtttgc tagaagaata 60 ccgtccgtga agagtttcaa ttcaacaagg tcaccctcat tacccgtgtg ctcaaatagt 120 ccactataaa aggctaaatc aataacaggt gttttactac gtactagttc ctcacgcatt 180 tccttagcct catcagatag cgtccacaca aactcgtctg cggtaacgtc ctctctgcg 239 <210> 315 <211> 239 <212> DNA <213> Artificial Sequence <400> 315 aacaattgtt tgacgtctta gcagatgacc tactaacaga tgaccaatat gagggtttct 60 taattggtaa catttataag tacattaaac gccacaaaga aaaaggtggc agtactgacc 120 ttgaaaaggc acgtgtgtat ttagatacgc taattaaatt tgaggaggaa aaataatgaa 180 cattcatact gatttactta ttttggctgt agacatgaac acaggtaagg caacgggag 239 <210> 316 <211> 239 <212> DNA <213> NCIMB 43666 node 248 <400> 316 aaaggctaaa tcaataacag gtgttttact acgtactagt tcctcacgca tttccttagc 60 ctcatcagat agcgtccaca caaactcgtc tgcggtaacg tcctctctgc gattcaatag 120 ttcagcatac tcctgtacac accatctaat aaactcagct ttctcatgtt cgttgtttag 180 tgcgtctctc atctcagtag acacatcagg gttaaattga cgcataaacg ttactttgt 239 <210> 317 <211> 239 <212> DNA <213> Artificial Sequence <400> 317 ttagttttaa gtgtccagag cgtttgtttg attatgcaaa aacctatatg aaagagtatc 60 ataatgtaga gttgcattat gatactaagt cagaagatat ttttgttata agaaatgata 120 tggtcctatg ggaataatgt ctaataagga ggaaaaataa atgattactg taacgattaa 180 taaatggcga aaagcaaaag tgacacctgt tattgttaca ggtacagtag aaccgcctg 239 <210> 318 <211> 239 <212> DNA <213> Artificial Sequence <400> 318 aaattaccta ccctaattaa cccattattg ttgctgaatg cgtctattgt gacggaatat 60 ttaactcctg ctggcaagta gttggttaat aagtcattgc tataatagac tattctgtta 120 gttgatgagt cgttaaacaa cactcgcatg ttcccgtttg aatattctat agtcgcacca 180 tttcctgtcc aaccattaat agtggggtct ttcgagaaat cataattcaa tactaaatt 239 <210> 319 <211> 239 <212> DNA <213> Artificial Sequence <400> 319 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga cacatcaact 120 aacagaagag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt aggtaattt 239 <210> 320 <211> 238 <212> DNA <213> Artificial Sequence <400> 320 cctaagtggg ctacaacatt cgcaccaaac gcatggtcag gaccttccct tacaacgcct 60 gtcaaagcac catcaacagg tttacgaaca ggagccttta aatttgagga ccggatagac 120 ttcggtacta cgtcagaaaa gaacggacgt tatgagttgg ttattttgac agacgctaat 180 gacatattaa tgtctatagc catccgtgac tctgacgcaa aaggcaatga agtgattg 238 <210> 321 <211> 238 <212> DNA <213> Artificial Sequence <400> 321 atagcgccca tcataagccc atgcgttgta tttaatcgta tatcctttag gtaattgacc 60 tgtgattttt gcatttgttg acgcgcttgc acgaacgttc atgacgcctt tagtagtagc 120 cttagcagtt tcagttgtcc atttaaggac tcctgacggt ttagagctat tacccatgtt 180 agatgacgcc gtgtctaggt cttgtgctaa gaaccatgag ttaataccat caacaaga 238 <210> 322 <211> 238 <212> DNA <213> Artificial Sequence <400> 322 ctctgattga gtaccagtca cactaatacc atcctgacca aagcgcgcca ctgagtaggt 60 tgtttggtta ctattatctg taaatgtcca gataatacgt gtccataggt attgaccacc 120 tgttacagtt ggtggtgttg cttgccaacc tgtggatggt gctgttgtac ctgaggtacc 180 tacagcgtaa gtaacagcga tagatttcac accattaccg gttgagccat ctacagga 238 <210> 323 <211> 238 <212> DNA <213> Artificial Sequence <400> 323 cgaaattgcc aactggtttc accgtcaata gtgggcacgt atcacagtac ccaaatacgt 60 ctaacgaccc tgctagacca aacctctaca tgggttcatg ggactacagc ccttctgagg 120 cgtttaatcc taagtgggct acaacattcg caccaaacgc atggtcagga ccttccctta 180 caacgcctgt caaagcacca tcaacaggtt tacgaacagg agcctttaaa tttgagga 238 <210> 324 <211> 238 <212> DNA <213> Artificial Sequence <400> 324 agagacccta taccatgtag aacgattgat ggtatacgtc agctcattcc gtacgaacat 60 ttacaagaaa tttaaaaata atgcttgaca actggttggg gttttgataa actaataaat 120 gtattaatac attaggagga aaacagatga ataaagaaga aacacacaaa gcgtttgaga 180 acgtcttaca ggaactaaag tttgattttg ataagttgaa atacggtaaa aaagtaga 238 <210> 325 <211> 238 <212> DNA <213> Artificial Sequence <400> 325 ttggtggtgt tgcttaccaa cctgtggatg gtgctgttgt acctgaggta cctacagcgt 60 aagtaacagc gatagatttc acaccattac cggttgagcc atctacagga ctatagttca 120 ctgtataggc tactgatgtt gtaccatcag tgtactccca cgttgtacgt gtccagaggt 180 atttaccttt ttctagagtt gggatggttg tactccatcc tgatgtaggt tcatcaac 238 <210> 326 <211> 238 <212> DNA <213> Artificial Sequence <400> 326 tgagcgcatt tgtttttcaa ttttcattga atcattctcc tttctatctc taatcattat 60 aacacaaaaa aggaggctta agcctcctta ggttatgcta aacgcccttg acgtctgtta 120 gataccagtt gtccgcgttg cttatcttta gttaaagcag ggtttagttc cgcagtaact 180 ttacgtttgt ctaagtagac gtccgtgtcc ttttctagta atgcttgtaa cagtgcgt 238 <210> 327 <211> 238 <212> DNA <213> Artificial Sequence <400> 327 caaggttctc aggcgtttcc catctattgg acattaggtt cactctcctt ataagtgaaa 60 tcacttgcga aaaatgaagc gtaacgttta tcattaatgt ctgtagggaa tacccaagtt 120 aaatcacgag cctcaatgta aatgctatct gtttctaagt caagcaatgc ctcacgtcca 180 atgagtaact cctccttacc tacaggcggt tctactgtac ctgtaacaat aacaggtg 238 <210> 328 <211> 238 <212> DNA <213> Artificial Sequence <400> 328 ttgtccgcgt tgcttatctt tagttaaagc agggtttagt tccgcagtaa ctttacgttt 60 gtctaagtag acgtccgtgt ccttttctag taatgcttgt aacagtgcgt gtgtttgttg 120 ttgctgtaca atcaattgag caattagctc atcattagaa ccctgaccag ctaccacggt 180 tgtttgtgat acacctaacc gcttttgtgc ctcagctagt agatacatag cgcgtgag 238 <210> 329 <211> 238 <212> DNA <213> Artificial Sequence <400> 329 gcacctgtag caaacaaagc ttccgttgtt aaaacatcta gatggctact caagtataaa 60 gactcagtag ccacaaggga ggtagtggat aaggtaacaa ggacaatgaa ctctacggaa 120 gacctacaca ttcgtgcagg ttccaagact agttacaagt catacggtct gttacctaag 180 ggcgtcacgt ttgaaacaac caaacgtcaa acgggtcaaa agattattaa aaacaacc 238 <210> 330 <211> 238 <212> DNA <213> Artificial Sequence <400> 330 aatgaacagg aacctcaaga cggtaccagt cactgaggta gatggtaaat taatattagg 60 ttttaatgta cctgaactaa gacaattgat taaataaaaa agagacctat ctaggtctct 120 ttactctttt acagaggttt tatttagaac gagttcacta tcactcaggt ttggcgtaga 180 tgggtcagga atttagttta ccgcgttgac caaggtcaag gctaaaagat acgggtta 238 <210> 331 <211> 238 <212> DNA <213> Artificial Sequence <400> 331 agagacccta taccatgtag aacgattgat ggtatacgtc agctcattcc gtacgaacat 60 ttacaagaaa tttaaaaata atgcttgaca actggttggg gttttgataa tctaataaat 120 gtattaaaac attaggagga aaacagatga ataaagaaga aacacacaaa gcgtttgaga 180 acgtcttaca ggaactaaag tttgattttg ataagttgaa atacggtaaa aaagtaga 238 <210> 332 <211> 238 <212> DNA <213> Artificial Sequence <400> 332 ttcattgtcc atgttacctt atccactacc tcccttgtgg ctactgagtc tttatacttg 60 agtagccatc tagatgtttt aacaacggaa gctttgtttg ctacaggtgc cttgtaggta 120 aatgggtttt ttgtaactgg tttaattccg ttgtttgatt ggatatgctc aaagttccaa 180 gtgaacttct tacccgtttg gtcacgtgtc attgtacagc ggaaccaaga tgatttgt 238 <210> 333 <211> 238 <212> DNA <213> Artificial Sequence <400> 333 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcacgatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca gaattcaata 120 ctacattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat cctgtacgtt tgcaatactc aatggctt 238 <210> 334 <211> 238 <212> DNA <213> Artificial Sequence <400> 334 aaagtaaaag tacgcgccaa agcaactaaa taccaaacgg gtcaaccagt gccaaacttt 60 gtaaaaggta aaacatacaa agtaaaagaa cgtaaaacag ttaatcaatc tgtaagtaaa 120 tatgcgtgtc ttgttgatgg tattaactca tggttcttag cacaagacct agacacggcg 180 tcatctaaca tgggtaatag ctctaaaccg tcaggagtcc ttaaatggac aactgaaa 238 <210> 335 <211> 238 <212> DNA <213> Artificial Sequence <400> 335 taacccgtat cttttagcct tgacctttgt caacgcggta aacttaattc ctgacccaac 60 tacgccaaac ctgagtgata gtgaactcgt tctaaataaa acctctgtaa tagagtaaag 120 agacctatat aggtctcttt tttatttaat caattgtctt agttcaggta cattaaaacc 180 taatattaat ttaccatcta cctcagtgac tggtaccgtc ttgaggttca tgttcatt 238 <210> 336 <211> 238 <212> DNA <213> Artificial Sequence <400> 336 acataattat cccccttaga ataaatcttg acccgcatat acgcaagaga tgtttatcca 60 tgcgcctgac ggaatcgcac tatctactgt agtaccatac ctacttacta taattgcacc 120 atccttgcgc acttctagta gtagcctgtt cattccagaa ccttgatgaa tgagtgttac 180 gttattcaat ggtctagccc aaactggtag aggttggtta atgacatatt gacctgcg 238 <210> 337 <211> 238 <212> DNA <213> Artificial Sequence <400> 337 ctgtatatgc aaacaacggt ttagacctaa tggaggcagt acagcaatat gagaaagtac 60 gcgctgaggg aatgcgttta caggagcaag aaatagaaaa gaaagtgact ctacgcgtgg 120 atggggacca ggatgaagtt gaggatgagt ttgttattgt taagattgct aaaaatgatt 180 taggtaacct tgatgttgcg tatgagctag tataacaacg ttttacacat aaatggta 238 <210> 338 <211> 238 <212> DNA <213> Artificial Sequence <400> 338 aatttagtat tgaattatga tttctcgaaa gacaccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga atcatcaact 120 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt aggtaatt 238 <210> 339 <211> 238 <212> DNA <213> Artificial Sequence <400> 339 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga atcatcaact 120 aacagaagag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt aggtaatt 238 <210> 340 <211> 238 <212> DNA <213> Artificial Sequence <400> 340 taacccgtat cttttagcct tgacctttgt caacgcggta aacttaattc ctgacccaac 60 tacgccaaac ctgagtgata gtgaactcgt tctaaataaa acctctgtaa ttgagtatat 120 agacctagat aggtctcttt tttatttaat caattgtctt agttcaggta cattacaacc 180 taatattaat ttaccatcta cctcagtgac tggtaccgtc ttgaggttca tgttcatt 238 <210> 341 <211> 238 <212> DNA <213> Artificial Sequence <400> 341 tctacttttt taccgtattt caacttatca aaatcaaact ttagttcctg taagacgttc 60 tcaaacgctt tgtgtgtttc ttctttattc atctgttttc ctcctaatgt attaatacat 120 ttattagatt atcaaaaccc caaccagttg tcaagcatta tttttaaatt tcttgtaaat 180 gttcgtacgg aatgagctga cgtataccat caatcgttct acatggtata gggtctct 238 <210> 342 <211> 237 <212> DNA <213> Artificial Sequence <400> 342 cgctgtagat gatgaattcc ccgtactgtg tacgtgaatt tgtccatacg gtcttacccc 60 tacttgtggt aaacctgagc gcatttgttt ttcaattttc attgaatcag tctcctttct 120 atctctaatc attataacac aaaaaaggag gcttaagcct ccttaggtta tgctaaacgc 180 ccttgacgtc tgttagatac catttgtccg cgttgcttat ctttagttaa agcaggg 237 <210> 343 <211> 237 <212> DNA <213> Artificial Sequence <400> 343 ccctgcttta actaaagata agcaacgcgg acaaatggta tctaacagac gtcaagggcg 60 tttaccataa cctaaggagg cttaagcctc cttttatgtg ttataaagag tagagataga 120 caggagaatg attcaatgaa aatagaaaaa caaatgcgct ccggtttacc acaagtaggg 180 gtaagaccgt atggacaaat tcacgtacac agtacgggga attcatcatc tacagcg 237 <210> 344 <211> 237 <212> DNA <213> Artificial Sequence <400> 344 taggctcgtc cataatgcgg gcacgcaatt catctaaaac attgtctaac tccgcgtcat 60 gtaattctaa tacctctgct aattttgtca tattattttt cctcctcatc gtctaatacc 120 tcaatttggt tatcatatac ccaccatagg tgaccatcaa tacttagttc aagttggtgc 180 gtttgtccgt caatttcttc agcgctatga gctactctga acacctctcc aacgtat 237 <210> 345 <211> 237 <212> DNA <213> Artificial Sequence <400> 345 gacgtcaatc atctgtgtaa tagcactctt tacaattcct gactctagaa tgtcaaaccc 60 cacagcgtgt gcgtgcagta cattgtaagc aaacattaga cgagcgtgta tcataatgtc 120 taattctata ggctcgtcca taatgcgggc acgcaattca tctaaaacat tgtctaactc 180 cgcgtcatgt aattctaata cctctgctaa ttttgtcata ttatttttcc tcctcat 237 <210> 346 <211> 237 <212> DNA <213> Artificial Sequence <400> 346 ttactaaagt ggtaatctcc atgagtcgta agaacggtaa atcattatta atcgcgggta 60 ttgcattata tgaacttctt tacgaacgtt cgccaatggc gtcccgtcaa atatattcta 120 cagccaaaac aaaagaccaa gcgtctattt gtttccgcat gattaagaca caactacagg 180 ctgttagaaa gaaatctaaa aaggttcgtg agtttacaaa agtaaacaaa tatgaca 237 <210> 347 <211> 237 <212> DNA <213> Artificial Sequence <400> 347 acaaaagacc aagcgtctat ttgtttccgc atgattaaga cacaactaca ggctgttaga 60 aagaaatcta aaaaggttcg tgagtttaca aaagtaaaca aatatgacaa tgagacaaaa 120 gatgactctt tttgtaaagc tctagcctca gactcatctg tattagatgg gttagatgtt 180 tgttgctcca tctttgatga aatggctgag aataaagata cttctattgt tgaggtt 237 <210> 348 <211> 237 <212> DNA <213> Artificial Sequence <400> 348 cgctgtagat gatgaattcc ccgtactgtg tacgtgaatt tgtccatacg gtcttacccc 60 tacttgtggt aaacctgagc gcatttgttt ttcaattttc attgaatcag tctcctttct 120 atctctactc attataacac aaaaaaggag gcttaagcct ccttaggtta tgctaaacgc 180 ccttgacgtc tgttagatac catttgtccg cgttgcttat ctttagttaa agcaggg 237 <210> 349 <211> 236 <212> DNA <213> Artificial Sequence <400> 349 aacagtacac tcatataggc gtcattatat tctgttaatc taacatgttc aaccttaacc 60 attaaaatac ctcctcaggt tgtaagtaaa cgtcaaaaac ctcctccact cagcttacca 120 ccgcacattg ggcaatagtg aatctcaaac tgagcggtat aaccttggtt gtcaacctca 180 gttgtgactg tcatagtttt cccgtttata aacacctcag tcatgtcagt cctccc 236 <210> 350 <211> 236 <212> DNA <213> Artificial Sequence <400> 350 cgtatacaaa ttgggtagta actagctcat acacgggtag agacacaatt tttatgagag 60 ctacagctcc aagtcaccca actacaggga cagtatggca aaaaccttct gaccctactg 120 tgctaaaatg gaacggtaca gcgtgggcaa actgggggat gtcaattaat aatattgtat 180 cagacaatgt tattgctgaa aacgggatgt ttaaaaaagt tagtggggtt gagatt 236 <210> 351 <211> 236 <212> DNA <213> Artificial Sequence <400> 351 cgtatacaaa ttgggtagta actagctcat acacgggtag agactcaatt tttattagtg 60 ctacagctcc aagtaaccca actacaggga cattatggca aaaacctaat gaccctactg 120 tgctaaactg gaacggtaca gcgtgggaaa actgggggat gtcaattaat aatattgtat 180 cagacaatgt tattgctgaa aacgggatgt ttaaaaaagt tagtggggtt gagatt 236 <210> 352 <211> 236 <212> DNA <213> Artificial Sequence <400> 352 gggaggactg acatgactga ggtgtttata aacgggaaaa ctatgacagt cacaactgag 60 gttgacaacc aaggttatac cgctcagttt gagattcact attgcccact gtgcggtggt 120 aagctgattg gaggaggttt ttgacgttta cttacaacct gaggaggtat tttaatgttt 180 aaggttgaac atgttagatt aacagaatat aatgacgcct atatgagtgt actgtt 236 <210> 353 <211> 236 <212> DNA <213> Artificial Sequence <400> 353 tcctgttcat tatctagagc atgaccaatt ttacagagca gtgtgtggcg cattagttct 60 aattctttac gcagtggtct attcattgtc tcactggcgt caaacataat agaggcatga 120 aataaattgt cataacaatt attcaatgtg tccccatctt taaagcccac aaatttatca 180 ttacccacat tgggaacaaa catatctgcc accaacttag caacatacat aaccct 236 <210> 354 <211> 236 <212> DNA <213> Artificial Sequence <400> 354 acgcctcagt aacacgtgac gtaagagcgc tagtagcttt cttaatcatt ccacgggcaa 60 cgtctagagg atattttatg agacctgagg tgtctactac gctagagact actttttcaa 120 ctaatttgct tgggttagtt gcgtagtccc aaacgtcacc aacaacactg ctaaccttat 180 caaacgcact tttagccatg tttttggcac cgttccagat gttttttacg cctcct 236 <210> 355 <211> 236 <212> DNA <213> Artificial Sequence <400> 355 gtctcctggt ctatatccac ttgttacgcg cataccaggg tatttggcaa tcaccttacg 60 cgctacatta gtaaggtatt tatacacacc cgctgtacct acagacgtat ctaggctccc 120 gctctcacac gcctcagtaa cacgtgacgt aagagcgcta gtagctttct taatcattcc 180 acgggcaacg tctagaggat attttatgag acctgaggtg tctactacgc tagaga 236 <210> 356 <211> 236 <212> DNA <213> Artificial Sequence <400> 356 acacatatca ccgcacaatt gaccaaattg gtagattggt agagatttca ctagtttcaa 60 ttcccgcata tgatgataca actgtagcag tggcacaacg gtcacaaaca gcgtttaaag 120 aacaaaaaag aaaattagaa ttagaacttg acattttaga attaatgtga tacagctaac 180 tcacccgcgg ttaataaacg cgtgttataa ttatttaaga aacataataa ggagtg 236 <210> 357 <211> 236 <212> DNA <213> Artificial Sequence <400> 357 gctccaccac tagggaactc agacgcattt gctactgtta ccgtagaaac gttgttagga 60 atagctccta atttgaacat taagcccgcc tttgtgtctg tagctactcc gtcaaaacgg 120 atggcacccg ctaacatttc accgtagaca ttgtggtctt gccaacgtac cgtcatttca 180 gtacgtttga acaaagtaat agcttgttct aagtcaccaa tgaataatag tttatc 236 <210> 358 <211> 236 <212> DNA <213> Artificial Sequence <400> 358 ctaccacaaa ggacccattc atctgaaaat ctatacctaa gtcctctcta ggttgtttgc 60 gtaggtctag tgcgtcatct ggtaacgtaa aataatagtg tatgcctcct gacggtgtat 120 agaccatgag ggtgttaggt atggtttcat gtcctaagtc tttcattaag gtagtaaaag 180 agtgtattcc gtttgcttta ccttttacgt ccccgtctac tactaataat ttgttt 236 <210> 359 <211> 236 <212> DNA <213> Artificial Sequence <400> 359 acctactgac ccactgctta taatcttata ttcaatcatc taatcacacc caatcatact 60 ctgtttgttc ttctgaattg tcgttctcta ggttccataa tagtttacct aatcgttgcg 120 cctctaggtc ctgttcatta tctagagcat gaccaatttt acagagcagt gtgtggcgca 180 ttagttctaa ttctttacgc agtggtctat tcattgtctc actggcgtca aacata 236 <210> 360 <211> 236 <212> DNA <213> Artificial Sequence <400> 360 tatggtcaac ctcatctgct aactcgtcta cctctaaacg agcgtctaac aacttttccc 60 ttagcatttc gttttctcta atgaggttat tacgttcacg aagtaataga actttatcct 120 ctttatccag gttctcaggc gtttcccatc tattggacat taggttcact ctccttataa 180 gtgaaatcac ttgcgaaaaa tgaagcgtaa cgtttatcat taatgtctgt agggaa 236 <210> 361 <211> 236 <212> DNA <213> Artificial Sequence <400> 361 ttcgtgcata ttgccttaat acgcgaacgt ttaccctcat tgtacatata gtccctcatg 60 tcctctttta ccattttacg cgttattcta cttctatcat ctgtgttgta tctgtttgct 120 agaagaagac cgtccgtgaa gagtttcaat tcaacaaggt caccctcatt acccgtgtgc 180 tcaaatagtc cactattaaa ggctaaatca ataacaggtg ttttactacg tactag 236 <210> 362 <211> 236 <212> DNA <213> Artificial Sequence <400> 362 tttgtgaccg ttgtgccact gctacagttg tatcatcata tgcgggaatt gaaactagtg 60 aaatctctac caatctacca atttggtcaa ttgtgcggtg atatgtgtat gtgtttgcgt 120 tgtatgacca cgtatcactt ttaaccataa acccaaacga acactgtgat aggtcaccgc 180 gttttactaa ctcatagacg tctctaccta attgggtatt tggtaattgt agacgg 236 <210> 363 <211> 236 <212> DNA <213> Artificial Sequence <400> 363 tatattaaaa ccatcacgga gttattatgg aatatgggcg ccatcatgtt tgaaaaggtt 60 tatccattat taaaacccat actagacacg atttttagtg cgttcggtcg cattttcaaa 120 caggtaagcg agttctataa tcagtatggt aaacaaatca tggaagcgtt catgaacttc 180 cttaatttta ttagtccact actaaaaatt gtaattggtt tagttggtga ctttgt 236 <210> 364 <211> 236 <212> DNA <213> Artificial Sequence <400> 364 catattatgg tcaatgcgta gattattttt aatttggtca attgttagca ttatctcact 60 cctatctaat aaaaaagagg taagaggttt taccccttac ccctcaatgg gttagttatt 120 aggctccagc tccaccacta gggaactcag acgcatttgc tactgttacc gtagaaacgt 180 tgttaggaat agctcctaat ttgaacatta agcccgcctt tgtgtctgta gctact 236 <210> 365 <211> 236 <212> DNA <213> Artificial Sequence <400> 365 aatctcaacc ccactaactt ttttaaacat cccgttttca gcaataacat tgtctgatac 60 aatattatta attgacatcc cccagttttc ccacgctgta ccgttccagt ttagcacagt 120 agggtcagta ggtttttgcc ataatgtccc tgtagttggg ttacttggag ctgtagcact 180 aataaaaatt gagtctctac ccgtgtatga gctagttact acccaatttg tatacg 236 <210> 366 <211> 236 <212> DNA <213> Artificial Sequence <400> 366 gggaggactg acatgactga ggtgtttata aacgggaaaa ctatgacagt cacaactgag 60 gttgacaacc aaggttatac cgctcagttt gagattcact attgcccact gtgcggtggt 120 aagctgagtg gaggaggttt ttgacgttta cttacaacct gaggaggtat tttaatgttt 180 aaggttgaac atgttagatt aacagaatat aatgacgcct atatgagtgt actgtt 236 <210> 367 <211> 235 <212> DNA <213> Artificial Sequence <400> 367 tacgcgggtt gttttgcata tgtagataag gaaacagaca ccatttttat tgactaccaa 60 taccgtacac ctctattgca ctgtgacgtt gatggagaac taatgattcc gctatttgca 120 agtgactgtg attatgttgt taatgagaga catgaggggt aaagaggaga ggtcaccatg 180 aatattttac tagaagaaac tgtggcattt aatttgggac tgagagacgc catct 235 <210> 368 <211> 235 <212> DNA <213> Artificial Sequence <400> 368 tgcgtaacgt tctgaccagt ttatttcctc gaactcataa aagtatgctt cactgtacgc 60 gtttataagc gcgtcaagag ggtcaatctt gttgcggtta acttgtttat caatcataat 120 taaatcgatt gactcttttg taaatgcgtt gtacacggct cttgtcaata gagggttgtt 180 aaagtgaagg accttgcccg ctcgtatatc cacttgtaat tgtttagtag gtggg 235 <210> 369 <211> 235 <212> DNA <213> Artificial Sequence <400> 369 agccctgatt ttttaaacga ttctaatgcc atgagtgtct tgcctgagcc aacctcacta 60 tgatttagat tatgtgtttc ccatttgtct atgaccattt gctgttggtc cgttggtatt 120 aacattatat tacctcctcc acattagtct atcatgaaac catgtagggt tgttgtgttg 180 ggtagtaggt tatattttgt tattattgta cacattcaaa aaccgtgtac acttt 235 <210> 370 <211> 235 <212> DNA <213> Artificial Sequence <400> 370 tcattgcctt ttgcgtcaga gtcacggatg gctatagaca ttaatatgtc attagcgtct 60 gtcaaaataa ccaactcata acgtccgttc ttttctgacg tagtaccgaa gtctatccgt 120 tcctcaattt taaaggctcc tgttcgtaaa cctgttgatg gtgctttgac aggcgttgta 180 agggaaggtc ctgaccatgc gtttggtgcg aatgttgtag cccacttagg tttaa 235 <210> 371 <211> 235 <212> DNA <213> Artificial Sequence <400> 371 cttctaaaac ttggttatgt tagtatagac gagtttattg aaaaggctag agaggaatta 60 taggaggtaa ctgcttatga aacttgtaaa tatgactaag aaaactagac ctacagaaga 120 taacttactc cattcaatat gggtacgcga atatggtggg tttttcctac catctaattt 180 aatgggtgga tgggttcttg ttgacatgaa tgaccctagc aacggttata atggt 235 <210> 372 <211> 235 <212> DNA <213> Artificial Sequence <400> 372 ggcaagacac tcatggcatt agaatcgttt aaaaaatcag ggctaaagaa actcgtagta 60 gtgtgccttg cgtctaaggt gtctgattgg gcttctgagg ggtctaatca aggtttaggt 120 ataattaccc taagtgggtc tccaaagctc agaggagagc ttctagaggc gtcaggaacg 180 caatatgtat caatcagctt tcaatcatca tggcgaacac ctgaattatt gaaat 235 <210> 373 <211> 235 <212> DNA <213> Artificial Sequence <400> 373 caacagcaaa tggtcataga caaatgggaa acacataatc taaatcatag tgaggttggc 60 tcaggcaaga cactcatggc attagaatcg tttaaaaaat cagggctcaa gaaactcgta 120 gtagtgtgcc ttgcgtctaa ggtgtctgat tgggcttctg aggggtctaa acaaggttta 180 ggtataatta ccctaagtgg gtctccaaag ctcagaggag agcttctaga ggcgt 235 <210> 374 <211> 235 <212> DNA <213> Artificial Sequence <400> 374 caaacattaa tggaggacta ctagaatgaa taaaccaagt ttaggactat atgttattat 60 tgctttgttg tttggaggca ttggcttaca ccgtatgtat gagggaaaac ttggctcagg 120 tttcttggtc ctattcttat tttggacggg tgtaccagtg gttatttcat ggattgacat 180 tattacagca ctaacaacgc gcagacactt attttcatag gaggaatagt atggg 235 <210> 375 <211> 235 <212> DNA <213> Artificial Sequence <400> 375 tgtttagact ctttaccaaa caattgtaat aaaagaaagt agtcagcgtt ctctatctct 60 gagagttgcc agctactttc taagagggat gaatatgttt cctcaagggt ttctaactgt 120 tcctcaatgg ttttttcctc aagtcctgtt atttctcctt tgaaactgta cccccgttga 180 cttgttcaaa gactccctgt actaatggta ataagtcctc aaaggctacg ttatc 235 <210> 376 <211> 235 <212> DNA <213> Artificial Sequence <400> 376 tagttttctt agtcatattt acaagtttca taagcagtta cctcctataa ttcctctcta 60 gccttttcaa taaactcgtc tatactaaca taaccaagtt ttagaaggtg tgccacctgt 120 agcattgcat agttagcata taatgtgagt gttcggtcat caacaccttg ctcacgcatg 180 tcgttttcta aatcaattaa aatacggtct gtgttttcaa cttctactaa taact 235 <210> 377 <211> 235 <212> DNA <213> Artificial Sequence <400> 377 cccatactat tcctcctatg aaaataagtg tctgcgcgtt gttagtgctg taataatgtc 60 aatccatgaa ataaccactg gtacacccgt ccaaaataag aataggaaca agaaacctga 120 gccaagtgtt ccctcataca tacggtgtaa gccaatgcct ccaaacaaca aagcaataat 180 aacatatagt cctaaacttg gtttattcat tctagtagtc ctccattaat gtttg 235 <210> 378 <211> 235 <212> DNA <213> Artificial Sequence <400> 378 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagg gtaggtactt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactaatg cttttagtat acatggtaat tcaaatgctt taatt 235 <210> 379 <211> 235 <212> DNA <213> Artificial Sequence <400> 379 actacagtaa aatggaaaag gttgaaaaag gtgagttaca aatgaatgag attgaggttt 60 tagatgatat gctaaactta gttctctcca ttttctcaaa cacaaaactt acttatgata 120 tgttagttga taacgtagcc tttgaggact tattaccatt agtacaggga gtctttgaac 180 aagtcaacgg gggtacagtt tcaaaggaga aataacagga cttgaggaaa aaacc 235 <210> 380 <211> 235 <212> DNA <213> Artificial Sequence <400> 380 tttttacgcc tcctgtaatt ttgtcaaaga agccagtacc ttttttgtat gcaaacttag 60 gacgtttatg acctaacact tgtgcagttt cttctgctgt taaaacgagg gttccttttc 120 gtccccacat cgttacgttc ttacctttag ggataaccgc ttgaccactt gggtcaataa 180 ccatttcagc accacgtcca tcattgacag tcatgggacc atctaccggg tgacc 235 <210> 381 <211> 235 <212> DNA <213> Artificial Sequence <400> 381 tccgtgtttt cttgacaatt tagaaaactc atccaattgc tctaacttgg agacaacaag 60 catgccacta tatacgtaag ttgtgaagtg ttcccttaca atatttgtaa gttctgacac 120 cctaatacag atggcgtctc tcagtcccaa attaaatgcc acagtttctt ctagtaaaat 180 attcatggtg acctctcctc tttacccctc atgtctctca ttaacaacat aatca 235 <210> 382 <211> 235 <212> DNA <213> Artificial Sequence <400> 382 caaacattaa tggaggacta ctagaatgaa taaaccaagt ttaggactat atgttattat 60 tgctttgttg tttggaggca ttggcttaca ccgtatgtat gagggaacac ttggctcagg 120 tttcttggtc ctattcttat tttggacggg tgtaccagtg gttatttcat ggattgacat 180 tattacagca ctaacaacgc gcagacactt attttcatag gaggaatagt atggg 235 <210> 383 <211> 234 <212> DNA <213> Artificial Sequence <400> 383 tctgtggacg cggaacgtgc taaagcatta gaggaagacg tggacaaatt agaaaaagga 60 gaggctagaa gtatggaaaa tgtaaagaaa atcaacccta cagaaaccgt tgctgaagct 120 gaggttcgtg cgttcggtga atatgtacgc tcacacggtt ctgtaaaagc acctgagtta 180 cgggatatta aattagaggg cgttgaggca attgttccgg ttgaccgcat tact 234 <210> 384 <211> 234 <212> DNA <213> Artificial Sequence <400> 384 tactaaatta tcatttgggt attggagtgt gaacctctct tttccaccac tactccatgc 60 gtaagctgtg tgtaaaaatg gattttgacc atcctgtacg tttgcaatac tcaatggctt 120 tgactctcat gccatgtttt ttacctcctc taataatcta cagaacaata atatgtatat 180 acatttgatt gtcctgcatt tactgtgatt gtttttcctg ttgctgtcca tgat 234 <210> 385 <211> 234 <212> DNA <213> Artificial Sequence <400> 385 caattggata aaaggactgc ctaagaaact aggggacgga attaaaggag gcgctcactt 60 cctaaaagac gcattcaaag gtatgtttaa cggagccttg aaagtaattg aaaaaccagt 120 gaacggactt attggcggtg caaactgggt tttagaaaaa ctaggcatgg acaagttaaa 180 aacatgggag gcacctgaat acgccaaagg tacaccaagt ggcggtcacc ctgt 234 <210> 386 <211> 234 <212> DNA <213> Artificial Sequence <400> 386 atgcttgttt atcaaggttg aacatggcac aaataaacgc tttagcaagg aacccatcaa 60 cacaaccata gaagcgtagc tcagtggcgt ctacgtcttt ccaacactaa gcaacctctt 120 tgcgtagttc ctcatctgtt agtttaccgc cttgttcaaa gtcaacatcc gtctctttga 180 cttctaaccc catgaaaccc tcatgttctt tcagtgaaaa ccctttgtgt tcat 234 <210> 387 <211> 234 <212> DNA <213> Artificial Sequence <400> 387 tttctgtagg gttgattttc tttacatttt ccatacttct agcctctcct ttttctaatt 60 tgtccacgtc ttcctctaat gctttagcac gttccgcgtc cacagagtta tctttatttt 120 cttctggttc aacctcgtct gcctcatcat ccttaggttg ttcatcctta ggttgctcgt 180 cagggttaac ctcgtctgtt tgttcgtctt gtgcctcacg aatttccttg atta 234 <210> 388 <211> 234 <212> DNA <213> Artificial Sequence <400> 388 gtaatgcggt caaccggaac aattgcctca acgccctcta atttaatatc ccgtaactca 60 ggtgctttta cagaaccgtg tgagcgtaca tattcaccga acgcacgaac ctcagcttca 120 gcaacgtgtt ctgtagggtt gattttcttt acattttcca tacttctagc ctctcctttt 180 tctaatttgt ccacgtcttc ctctaatgct ttagcacgtt ccgcgtccac agat 234 <210> 389 <211> 234 <212> DNA <213> Artificial Sequence <400> 389 cacgtttgaa acaaccaaac gtcaaacggg tcaaaagatt attaaaaaca accaatggta 60 ttatgtaact aagaactcag gtaagaaaat acctgcctca ggatgggtca gtggatatta 120 cctacaacac actaaacgtg tggaacacaa gaagaaagag acctactcta ttgttgcaaa 180 aatgcaggtg acagattcaa gattcacatg gatgggaaca ggtaaatcta aaga 234 <210> 390 <211> 234 <212> DNA <213> Artificial Sequence <400> 390 acactaaacg tgtggaacac aagaagaaag agacctactc tattgttgca aaaatgcagg 60 tgacagattc aagattcaca tggatgggaa caggtaaatc taaagacagt aaaaacccat 120 ttaaagcagg ggacaagatt gtcataaaca cacatgataa aaccttcttt gtaaatggtg 180 tagaacgtga ggacctagca accataggaa atcagtggga aggcttcgca cttg 234 <210> 391 <211> 234 <212> DNA <213> Artificial Sequence <400> 391 cattgagtat tgcaaacgta caggatggtc aaaatccatt tttacacaca gcttacgcat 60 ggagtagtga tggaaaagag aggttcacac tccaataccc aaatgataat ttagtattga 120 attatgagtt ctcgaaagac cccactatta atggttggac aggaaatggt gcgactatag 180 aatattcaaa cgggaacatg cgagtgttgt ttaacgactc atcaactaac agaa 234 <210> 392 <211> 234 <212> DNA <213> Artificial Sequence <400> 392 acagggtgac cgccacttgg tgtacctttg gcgtattcag gtgcctccca tgtttttaac 60 ttgtccatgc ctagtttttc taaaacccag tttgcaccgc caataattcc gttcactggt 120 ttttcaagta ctttcaaggc tccgttaaac atacctttga atgcgtcttt taggaagtga 180 gcgcctcctt taattccgtc ccctagtttc ttaggcagtc cttttatcca attg 234 <210> 393 <211> 234 <212> DNA <213> Artificial Sequence <400> 393 ttattggcgg tgcaaactgg gttttagaaa aactaggcat ggacaagtta aaaacatggg 60 aggcacctga atacgccaaa ggtacaccaa gtggcggtca ccctgtcgat ggtcccatga 120 ctgtcaatga tggacgtggt gctgaaatgg ttattgaccc aagtggtcaa gcggttatcc 180 ctaaaggtaa gaacgtaacg atgtggggac gaaaaggaac ccacgtttta acag 234 <210> 394 <211> 234 <212> DNA <213> Artificial Sequence <400> 394 atcatggaca gcaacaggaa aaacaatcac agtaaatgca ggacaatcaa atgtatatac 60 atattattgt tctgtagatt attagaggag gtaaaaaaca tggcattaga gtcaaagcca 120 ttgagtagtg caaacgtaca ggatggtcaa aatccatttt tacacacagc ttacgcatgg 180 agtagtgatg gaaaagagag gttcacactc caatacccaa atgataattt agta 234 <210> 395 <211> 234 <212> DNA <213> Artificial Sequence <400> 395 caattggata aaaggactgc ctaagaaact aggggacgga attaaaggag gcgctcactt 60 cctaaaagac gcattcaaag gtatgtttaa cggagccttg aaagtacttg aaaaaccagt 120 gaacggactt attggcggtg caaactgggt tttagaaaaa ctaggcatgg acaagttaaa 180 aacatgggag gcacctgaat acgccaaagg tacaccaagt ggcggtcacc ctgt 234 <210> 396 <211> 234 <212> DNA <213> Artificial Sequence <400> 396 atgaacacaa agggttttca ctgaaagaac atgagggttt catggggtta gaagtcaaag 60 agacggatgt tgactttgaa caaggcggta aactaacaga tgaggaccta cgcaaagagg 120 ttgcttagtg ttggaaagac gtagacgcca ctgagctacg cttctatggt tgtgttgatg 180 ggttacttgc taaagcgttt atttgtgcca tgttcaacct tgataaacaa gcat 234 <210> 397 <211> 234 <212> DNA <213> Artificial Sequence <400> 397 tactaaatta tcatttgggt attggagtgt gaacctctct tttccatcac tactccatgc 60 gtaagctgtg tgtaaaaatg gattttgacc atcctgtacg tttgcactac tcaatggctt 120 tgactctcat gccatgtttt ttacctcctc taataatcta cagaacaata atatgtatat 180 acatttgatt gtcctgcatt tactgtgatt gtttttcctg ttgctgtcca tgat 234 <210> 398 <211> 233 <212> DNA <213> Artificial Sequence <400> 398 cactgggaac gaacaactta gacctgtata aatgggcgtg taaattgtac atgacaacct 60 ttttcagtga acctcttgac gagagtgagt ttgaattaac agtaatgagt atttggaaac 120 gtgaaaatgg tagatgatta tttgacacct gttattaatg aaagcaatga gacccgtacc 180 attaccatct gcatggtcaa cggacgctct tacacatata agggttcccc aga 233 <210> 399 <211> 233 <212> DNA <213> Artificial Sequence <400> 399 tcctatagac atttgtcagt tcgccaaaat acagagttcg ccactaaata cttgtcagag 60 ggtggtacga gtattcattt acaccagagt ggtagttatt actcatatga gaacctcaag 120 gcgcagactg ggctagacga aagacatgat aaggagttta tacaatactg caaagaaaga 180 ggttatgatt atgtataagt acgtagtacg ctacaaagac tttgatggtt cat 233 <210> 400 <211> 233 <212> DNA <213> Artificial Sequence <400> 400 attgacccat atatagcgga tatgcgttcg cgaaatcttc agatgggttt ggggtgtaga 60 tggttgccgt gtttcctagt tcgattttta tttttgttat agttataatt aaagcatttg 120 aattaccatg tatactaaaa gcattagttg cccctgcggt tataccctca aatttatacg 180 ttgaaggtgt gtcaccttgt tttattgttt gccatgtact gagagcgtca aaa 233 <210> 401 <211> 233 <212> DNA <213> Artificial Sequence <400> 401 ggggtaagac cgtatggaca aattcacgta cacagtacgg ggaattcatc atctacagcg 60 caaaacgagg cagactatca tatgcgcaga cccgtcaaca gtgggttctt ctcgcacgta 120 gtaggtaccg ggcgagtaat tcaaacagca cgcacaaacg cgggctttta tgacgtaggt 180 ggcggatgga actcgtgggg atatgcggca attgaattga ttgaatcgca caa 233 <210> 402 <211> 233 <212> DNA <213> Artificial Sequence <400> 402 aaaacaaaat gagtaaagta tttgaggata attttactaa acccctacca gtggggacga 60 aggtgcgctt gattaaacct gaaccaactg aattttttat gaatgtgggt tacgagcgtg 120 acagggaata cgttggagag gtgttcagag tagctcatag cgctgaagaa attgacggac 180 aaacgcacca acttgaacta agtattgatg gtcacctatg gtgggtatat gat 233 <210> 403 <211> 233 <212> DNA <213> Artificial Sequence <400> 403 gttagttaaa gttaaagaaa tggcgcagtt gggtaattat ctaatttata gacgacataa 60 cggagatagt gcctgtctta ctatcatgga cttcacacac aaccccttgg cgggaacacg 120 tgagataagt tgtgaagatg gtgcacttga cttacttaat aatgttgtac ctgctattaa 180 aaccacgtca cctcaatcgt ttcaatacta ctggaacatt gtcatgagag aca 233 <210> 404 <211> 233 <212> DNA <213> Artificial Sequence <400> 404 acggttcaca ggacaatagt atacagtatt ggggaatctt tgacgcagta acggctacac 60 caacagcagg agccactaaa ttaactaaaa cagcagtgtc aacaatacgt cctgcatacc 120 tatcaaaggg ctacagtgct ttgcgcggta caacgtacac tgtatcaggg agtgtattca 180 tctctaaggg gtggactggt agtctagcaa caacagaatt aattgtgcgt gtt 233 <210> 405 <211> 233 <212> DNA <213> Artificial Sequence <400> 405 cactgggaac gaacaactta gacctgtata aatgggcgtg taaattgtac atgacaacct 60 gtttcagtga acctcttgac gagagtgagt ttgaattaac agtaaggagt atttggaaac 120 gtgaaaaagg tagatgatta tatgacacct gttattaatg aaagcaatga gacccgtacc 180 attaccatct gcatggtcaa cggacgctct tacacatata agggttcccc aga 233 <210> 406 <211> 233 <212> DNA <213> Artificial Sequence <400> 406 aacacgcaca attaattctg ttgttgctag actaccagtc caccccttag agatgaatac 60 actccctgat acagtgtacg ttgtaccgcg caaagcactg tagccatttg ataggtatgc 120 aggacgtctt gttgacactg ctgttttagt taatttagtg gctcctgctg ttggtgtagc 180 cgttactgcg tcaaagattc cccaatactg tatactattg tcctgtgaac cgt 233 <210> 407 <211> 233 <212> DNA <213> Artificial Sequence <400> 407 attgagtatt gcaaaggtac aggatggtca aaatccattt ttacacacag cttacgcatg 60 gagtagtgat ggaaaagaga ggttcacact ccaataccca aatgataatt tagtattgaa 120 ttatgatgtc tcgaaagacc ccactattaa tggttggaca ggaaatggtg cgactataga 180 atattcaaac gggaacatgc gagtgttgtt taacgactca tcaactaaca gaa 233 <210> 408 <211> 233 <212> DNA <213> Artificial Sequence <400> 408 gatgtcacta agtccatcac tagcgttctc cattgattta agagctttac ttgataattt 60 agcctgtgac tctaatttag atagggagat tctagcctcc tcaacgtctt tagagttttc 120 accgaactcc tgagaactca tttcaatagc gcgcttttgt gcctcaatag ctttctcagt 180 taaggagatt gaacgtttta gaccctcctg tttagcctca agtgcgcccg ctg 233 <210> 409 <211> 233 <212> DNA <213> Artificial Sequence <400> 409 gttagttaaa gttaaagaaa tggcgcagtt gggtaattat ctaatttata gacgacataa 60 cggagatagt gcctgtctta ctatcatgga cttcacacac aacccattgg cgggaacacg 120 tgagatacgt tgtgaagatg gtgcacttga cttacttaat aatgttgtac ctgctattaa 180 aaccacgtca cctcaatcgt ttcaatacta ctggaacatt gtcatgagag aca 233 <210> 410 <211> 233 <212> DNA <213> Artificial Sequence <400> 410 ccgactgtta gacccgcaaa agtgcccact aatgaggtga ccgcaccgat taccgcgcca 60 ccttttagag acattacacc atctaatagt ccacctaccc catctgtagc ctcgtctgct 120 ccaccttgga tgtcactaag tccatcacta gcgttctcca ttgatttaag agctttactt 180 gataatttag cctgtgactc taatttagat agggagattc tagcctcctc aac 233 <210> 411 <211> 233 <212> DNA <213> Artificial Sequence <400> 411 tcctatagac atttgtcagt tcgccaaaat acagagttcg ccactaaata cttgtcagag 60 ggtggtacga gtattcattt acaccagagt ggtagttatt actcagatga gaacctcaag 120 gcgcagaatg ggctagacga aagacatgat aaggagttta tacaatactg caaagaaaga 180 ggttatgatt atgtataagt acgtagtacg ctacaaagac tttgatggtt cat 233 <210> 412 <211> 233 <212> DNA <213> Artificial Sequence <400> 412 gttagttaaa gttaaagaaa tggcgcagtt gggtaattat ctaatttata gacgacataa 60 cggagatagt gcctgtctta ctatcatgga cttcacacac aaccccttgg cgggaacacg 120 tgagatacgt tgtgaagatg gtgcacttga cttacttaat aatgttgtac ctgctattaa 180 aaccacgtca cctcaatcgt ttcaatacta ctggaacatt gtcatgagag aca 233 <210> 413 <211> 233 <212> DNA <213> Artificial Sequence <400> 413 tcctatagac atttgtcagt tcgccaaaat acagagttcg ccactaaata cttgtcagag 60 ggtggtacga gtattcattt acaccagagt ggtagttatt actcagatga gaacctcaag 120 gcgcagactg ggctagacga aagacatgat aaggagttta tacaatactg caaagaaaga 180 ggttatgatt atgtataagt acgtagtacg ctacaaagac tttgatggtt cat 233 <210> 414 <211> 233 <212> DNA <213> Artificial Sequence <400> 414 atcatatacc caccataggt gaccatcaat acttagttca agttggtgcg tttgtccgtc 60 aatttcttca gcgctatgag ctactctgaa cacctctcca acgtagtccc tgtcacgctc 120 gtaacccaca ttcataaaaa attcagttgg ttcaggttta atcaagcgca ccttcgtccc 180 cactggtagg ggtttagtaa aattatcctc aaatacttta ctcattttgt ttt 233 <210> 415 <211> 233 <212> DNA <213> Artificial Sequence <400> 415 cactgggaac gaacaactta gacctgtata aatgggcgtg taaattgtac atgacaacct 60 gtttcagtga acctcttgac gagagtgagt ttgaattaac agtaaggagt atttggaaac 120 gtgaaaatgg tagatgatta tatgacacct gttattaatg aaagcaatga gacccgtacc 180 attaccatct gcatggtcaa cggacgctct tacacatata agggttcccc aga 233 <210> 416 <211> 233 <212> DNA <213> Artificial Sequence <400> 416 aacacgcaca attaattctg ttgttgctag actaccagtc caccccttag agatgaatac 60 actccctgat acagtgtacg ttgtaccgcg caaagcactg tagccctttg ataggtatgc 120 aggacgtctt gttgacactg ctgttttagt taatttagtg gctcctgctg ttggtgtagc 180 cgttactgcg tcaaagattc cccaatactg tatactattg tcctgtgaac cgt 233 <210> 417 <211> 232 <212> DNA <213> Artificial Sequence <400> 417 aggctatccg ccagagtgtg tgaattggtt tgtcaatagt agtatagaag aacatgtaat 60 ttgtaaatgt gcagatggtg gctcatttag ttttaagtgt ccagagcgtt tgtttgatta 120 tgcaaaatcc tatatgaaag agtatcataa tgtagagttg cattatgata ctaagtcaga 180 agatattttt gttataagaa atgatatgtt cctatgggaa taatgtctaa ta 232 <210> 418 <211> 232 <212> DNA <213> Artificial Sequence <400> 418 tcgtaactac aggtaacatt tatgagttaa ctacagcaat acgagcatta ggtggtacac 60 cagaggggtc aaacaacccc attacattaa gtgggttctc gtgggttgac ccagatgggc 120 gttttaatct tgagaagggg gttatgattg acacgcaaga agctcctaaa tggtccagtg 180 tcttatcaac aacaggaggt ttgttcacac gtgctgtaac gtatgacacc ct 232 <210> 419 <211> 232 <212> DNA <213> Artificial Sequence <400> 419 tcccatacta ttcctcctat gaaaataagt gtctgcgcgt tgttagtgct gtaataatgt 60 caatccatga aataaccact ggtacacccg tccaaaataa gaataggaac aagaaacctg 120 agccaagatt tccctcatac atacggtgta agccaatgcc tccaaacaac aaagcaataa 180 taacatatag tcctaaactt ggtttattca ttctagtagt cctccattaa tg 232 <210> 420 <211> 232 <212> DNA <213> Artificial Sequence <400> 420 tttagatttc tttctaacag cctgtagttg tgtcttaatc atgcggaaac aaatagacgc 60 ttggtctttt gtattggctg tagaatatat ttgacgggac gccagtggcg aacgttcgta 120 aagaagttca tataatgcaa tacccgcgat taataatgat ttaccgttct tacgactcat 180 ggagattacc actttagtaa atcgcctgta ccctgagtcc tttttaaccc at 232 <210> 421 <211> 232 <212> DNA <213> Artificial Sequence <400> 421 atttcaaaac tagacgctgg catgctagtc atttattgta atacttacgc tatttacagt 60 caggcaactc aagaggtatc tgaatacggt tatcttgacg aaaatgggaa accatcaggc 120 gcctttaagg ttatgaatga aacatctaaa caactaaagt ctctagcaag ttcattagga 180 ctttcaattg atggacgtat gaaattaatt atcccaagca tgaaaacgaa ag 232 <210> 422 <211> 232 <212> DNA <213> Artificial Sequence <400> 422 tttccctcat acatacggtg taagccaatg cctccaaaca acaaagcaat aataacatat 60 agtcctaaac ttggtttatt cattctagta gtcctccatt aatgattgta tgaaatcgtt 120 taactcgtcc acgtagtcgt atagagaatc aaggtcatca attaatttat catttttctc 180 aatgagttca tcaacttcct tatctaaaaa ttcaacctga ccacgtaggt ta 232 <210> 423 <211> 232 <212> DNA <213> Artificial Sequence <400> 423 ccggttgagc catctacagg aatatagttc actgtatagg ctactgatgt tgtaccatca 60 gtgtactccc acgttgtacg tgtccatagg tatttacctt tttcgagagt tgggatggtt 120 gtactccatc ctgatgtagg ttcatcaacg cttgaggtat tgattgccca ctctgtttta 180 gttgatttga cagaggcgcc attttgtccc gttgttctca tccacgtgta ct 232 <210> 424 <211> 232 <212> DNA <213> Artificial Sequence <400> 424 tgtgtaagag cgtccgttga ccatgcagat ggtaatggta cgggtctcat tgctttcatt 60 aataacaggt gtcatataat catctacctt tttcacgttt ccaactactc attactgtta 120 attcaaactc actctcgtca agaggttcac tgaaacaggt tgtcatgtac aatttacacg 180 cccatttata caggtctaag ttgttcgttc ccagtgctaa cattcctgct gt 232 <210> 425 <211> 232 <212> DNA <213> Artificial Sequence <400> 425 taatattcaa cactaacaat gtagtacggt tgtattacta cattcacggg cacagagctt 60 agtagcataa tctgaaaaac ctctcctgtt tgcatacgtt caataacaaa ctctggggaa 120 cccttatctg tgtaagagcg tccgttgacc atgcagatgg taatggtacg ggtctcattg 180 ctttcattaa taacaggtgt catataatca tctacctttt tcacgtttcc aa 232 <210> 426 <211> 232 <212> DNA <213> Artificial Sequence <400> 426 ccggttgagc catctacagg aatatagttc actgtatagg ctactgatgt tgtaccatca 60 gtgtactccc acgttgtacg tgtccatagg tagttacctt tttctagagt tgggatggtt 120 gtactccctc ctgatgtagg ttcatcaacg cttgaggtat tgattgcccc ctctgtttta 180 gttgatttga cagaggcgcc attttgtccc gttgttctca tccacgtgta ct 232 <210> 427 <211> 232 <212> DNA <213> Artificial Sequence <400> 427 tgttatacta gctcatacgc aacatcaagg ttacctaaat catttttagc aatcttaaca 60 ataacaaact catcctcaac ttcatcctgt tccccatcca cgcgaatagt cactttcttt 120 tctatttctt gctcctgtaa acgcattccc tcagcgcgta ctttctcata ttgctgtact 180 gcctccatta ggtctaaacc gttgtttgca tatacagcta gaatagaggt tc 232 <210> 428 <211> 232 <212> DNA <213> Artificial Sequence <400> 428 tgcctcacgt ccaatgagta actcctcctt acctacaggc ggttctactg tacctgtaac 60 aataacaggt gtcacttttg cttttcgcca tttattaatc gttacagtaa tcatttattt 120 ttcctccata ttagacatta ttcccatagg aacatatcat ttcttataac aaaaatatct 180 tctgacttag tatcataatg caactctaca ttatgatact ctttcatata gg 232 <210> 429 <211> 232 <212> DNA <213> Artificial Sequence <400> 429 ttttgtaact ggtttaattc cgttgtttga ttggatatgc tcaaagttcc aagtgaactt 60 cttacccgtt tggtcacgtg tcattgtaca gcggaaccaa gatgttttgt acttagttac 120 gtctgtcttg atagatttta gtaacttgtt accgtaccag tattcaacaa tcacttcatt 180 gccttttgcg tcagagtcac ggatggctat agacattaat atgtcattag cg 232 <210> 430 <211> 232 <212> DNA <213> Artificial Sequence <400> 430 ccggttgagc catctacagg aatatagttc actgtatagg ctactgatgt tgtaccatca 60 gtgtactccc acgttgtacg tgtccatagg tatttacctt tttcgagagt tgggatggtt 120 gtactccctc ctgatgtagg ttcatcaacg cttgaggtat tgattgccca ctctgtttta 180 gttgatttga cagaggcgcc attttgtccc gttgttctca tccacgtgta ct 232 <210> 431 <211> 232 <212> DNA <213> Artificial Sequence <400> 431 ctttcgtttt catgcttggg ataattaatt tcatacgtcc atcaattgaa agtcctaatg 60 aacttgctag agactttagt tgtttagatg tttcattcat aaccataaag gcgcctgatg 120 gtttcccatt ttcgtcaaga taaccgtatt cagatacctc ttgagttgcc tgactgtaaa 180 tagcgtaagt attacaataa atgactagca tgccagcgtc tagttttgaa at 232 <210> 432 <211> 231 <212> DNA <213> Artificial Sequence <400> 432 tcctcctcat ctaacatact aagttcttcg cgtaagaact tgacaacccc ttctaatagc 60 tcaattgttt cctctttgtt taggttctca ccttccccct ctagtgctcc cgttgcctta 120 cctgtgttca tgtctacagc caaaataagt aaatcagtat gaatgttcat tatttttcct 180 cctcaaattt aattagcgta tctaaataca cacgtgcctt ttcaaggtca g 231 <210> 433 <211> 231 <212> DNA <213> Artificial Sequence <400> 433 ctaattaaat ttgaggagga aaaataatga acattcatac tgatttactt attttggctg 60 tagacatgaa cacaggtaag gcaacgggag caatagaggg ggaaggtgag aacctaaaca 120 aagaggacac aattgagcta ttagaagggg ttgtcaagtt cttacgcgaa gaacttagta 180 tgttagatga ggaggaaaac gaagatgaat aactatgagt tattagtaga a 231 <210> 434 <211> 231 <212> DNA <213> Artificial Sequence <400> 434 ctaattaaat ttgaggagga aaaataatga acattcatac tgatttactt attttggctg 60 tagacatgaa cacaggtaag gcaacgggag caatagaggg ggacggtgag aacctaaaca 120 aagaggaaac aattgagcta ttagaagggg ttgtcaagtt cttacgcgaa gaacttagta 180 tgttagatga ggaggaaaac gaagatgaat aactatgagt tattagtaga a 231 <210> 435 <211> 231 <212> DNA <213> Artificial Sequence <400> 435 tggtttaggt ttgttgtcag tattggaact atttccacca aacccatttt taatgtcttt 60 agcaaactgc tctttactaa ttccccattt acgcaagtat ggataggggt caatatggtc 120 agaaccagtg tttggttgat gtgccgttgc atatgcgtga gaaatgacac ctgtattccc 180 ttggtctagc gtcttaggta gtcccgcttc atcacataat agacgaatta a 231 <210> 436 <211> 231 <212> DNA <213> Artificial Sequence <400> 436 taaatctgtg gacgcggaac gtgctaaagc attagaggaa gacgtggaca aattagaaaa 60 aggagaggct agaagtatgg aaaatgtaaa gaaaatcaac cctccagaaa acgttgctga 120 agctgaggtt cgtgcgttcg gtgaatatgt acgctcacac ggttctgtaa aagcacctga 180 gttacgggat attaaattag agggcgttga ggcaattgtt ccggttgacc g 231 <210> 437 <211> 231 <212> DNA <213> Artificial Sequence <400> 437 aaattggtca tgagattgag cttttagata gagaaaaatg tatacacttt tatagagacg 60 gacgttattt tgctacaatt gacaaaaaag gttttagtgg tggttatcac cttaaacaaa 120 cactaaagta gggtaggaat taaaatgaac acatataccg tttattaccg taacattgat 180 gagcactatt gctgtagtat tcacgttgac gcatatacta ttgaacaagc t 231 <210> 438 <211> 231 <212> DNA <213> Artificial Sequence <400> 438 gttactaagc tacagattgt cagccctcat acaattacaa tcttacaaga cacagcgagt 60 aaagaattgt catatgagta cattgaccct gacaatcaaa agacagaaac catcaagggt 120 aaagacatgt tacattttag actgaactca attgacggca tttcaggacg ctcaccacta 180 aaagcgctag tacctgaaat agatatgcaa acaagcggaa cacgtttgtt a 231 <210> 439 <211> 231 <212> DNA <213> Artificial Sequence <400> 439 tgtttggttg atgtgccgtt gcatatgcgt gagaaatgac acctgtattc ccttggtcta 60 gcgtcttagg tagtcccgct tcatcacata atagacgaat taagtctact agtagcttat 120 agtctttcat aaactcttct ttggttttgt gcgattcaat caattcaatt gccgcatatc 180 cccacgagtt ccatccgcca cctacgtcat aaaagcccgc gtttgtgcgt g 231 <210> 440 <211> 231 <212> DNA <213> Artificial Sequence <400> 440 tactatgacc gttttgaacg tgactatgtt aatgagggaa ttgaatatag tttgaaagat 60 aaacatggtg ctaccttgag tgtcgctagg ttatataaag ataaaacagt gattaaaatt 120 actgatttta cgaatgatgt agtaagcgta cacttaacag acgcacaact tagagacttg 180 agaaaaattt tgaaagaagt ttaaaaatag tgttgacaga tgactaatcg t 231 <210> 441 <211> 231 <212> DNA <213> Artificial Sequence <400> 441 gctttattga ttgtgttcaa cccaatacgt gttaagtggc gagcaatcaa cgcaactaag 60 tcagggtcag agtcttgaat tgcttcgtta gacattggaa tatatccgcg gtgtgtttct 120 accttccctt ctacattttt gaatgttggt tctgccaatt tagggttttc tactaactca 180 gctactgtgt tcattaccgc gttagttgtt tccaaaatag ggtaagaacc t 231 <210> 442 <211> 231 <212> DNA <213> Artificial Sequence <400> 442 taggggagga atttaaatga acacatatac agtttattac cgtaacattg atgagcacta 60 ttgctgtagt attcacgttg acgcatatac tattgaacaa gctcttaata aagggttaca 120 gtaccttgaa tatgaagaac atttagacta ctcagaaatt gagatttgtc acgttgagaa 180 agtggggtaa atgaaatgac accagaaaac gttgaaaaag agtacggtgt g 231 <210> 443 <211> 231 <212> DNA <213> Artificial Sequence <400> 443 aaattaatca aggaaattcg tgaggcacaa gacgaacaaa cagacgaggt taaccctgac 60 gagcaaccta aggatgaaca acctaaggat gatgaggcag acgaggttga accagaagaa 120 aataaagcta aatctgtgga cgcggaacgt gctaaagcat tagaggaaga cgtggacaaa 180 ttagaaaaag gagaggctag aagtatggaa aatgtaaaga aaatcaaccc t 231 <210> 444 <211> 231 <212> DNA <213> Artificial Sequence <400> 444 aggtaggtca cagagtagta tgtgtagaca ctttatgtgt agaagatata ttggaaaaag 60 gtaaacgata taccattgtt ggagtaggca gccttttcgt gcaggttgat ggtattgatg 120 aatggttcta ctatgaccgt tttgaacgtg actatgttaa tgagggaatt gaatatagtt 180 tgaaagataa acatggtgct accttgagtg tcgctaggtt atataaagat a 231 <210> 445 <211> 231 <212> DNA <213> Artificial Sequence <400> 445 ctaattaaat ttgaggagga aaaataatga acattcatac tgatttactt attttggctg 60 tagacatgaa cacaggtaag gcaacgggag caatagaggg ggacggtgag aacctaaaca 120 aagaggacac aattgagcta ttagaagggg ttgtcaagtt cttacgcgaa gaacttagta 180 tgttagatga ggaggaaaac gaagatgaat aactatgagt tattagtaga a 231 <210> 446 <211> 231 <212> DNA <213> Artificial Sequence <400> 446 gctttattga ttgtgttcaa cccaatacgt gttaagtggc gagcaatcaa cgcaactaag 60 tcagggtcag agtcttgaat tgcttcgtta gacattggaa tatctccgcg gtgtgtttct 120 accttccctt ctacattttt gaatgttggt tctgccaatt tagggttttc tactaactca 180 gctactgtgt tcattaccgc gttagttgtt tccaaaatag ggtaagaacc t 231 <210> 447 <211> 231 <212> DNA <213> Artificial Sequence <400> 447 gttactaagc tacagattgt cagccctcat acaattacaa tcttacaaga cacagcgagt 60 aaagaattgt catatgagta cattgaccct gacaatcaaa agaaagaaac catcaagggt 120 aaagacaagt tacattttag actgaactca attgacggca tttcaggacg ctcaccacta 180 aaagcgctag tacctgaaat agatatgcaa acaagcggaa cacgtttgtt a 231 <210> 448 <211> 231 <212> DNA <213> Artificial Sequence <400> 448 gttactaagc tacagattgt cagccctcat acaattacaa tcttacaaga cacagcgagt 60 aaagaattgt catatgagta cattgaccct gacaatcaaa agacagaaac catcaagggt 120 aaagacaagt tacattttag actgaactca attgacggca tttcaggacg ctcaccacta 180 aaagcgctag tacctgaaat agatatgcaa acaagcggaa cacgtttgtt a 231 <210> 449 <211> 230 <212> DNA <213> Artificial Sequence <400> 449 tgtacgtgtc cataggtatt tacctttttc tagagttggg atggttgtac tccatcctga 60 tgtaggttca tcaacgcttg aggtattgat tgcccactct gtgttagttg atttgacaga 120 ggcgccattt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 180 ttgagtatag ttactatatt gacccatata tagcggatat gcgttcgcga 230 <210> 450 <211> 230 <212> DNA <213> Artificial Sequence <400> 450 aggtacgaaa ttgccaactg gtttcaccgt caatagtggg cacgtatcac agtacccaaa 60 tacgtctaac gaccctgcta gaccaaacct ctacatgggt tcatgggact acagcccttc 120 tgaggcgatt aaacctaagt gggctacaac attcgcacca aacgcatggt caggaccttc 180 ccttacaacg cctgtcaaag caccatcaac aggtttacga acaggagcct 230 <210> 451 <211> 230 <212> DNA <213> Artificial Sequence <400> 451 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagg gtcggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactaatg cttttagtat acagggtaat tcaaatgctt 230 <210> 452 <211> 230 <212> DNA <213> Artificial Sequence <400> 452 gacccgctac agtattcaag tcatctacgt ggtgttgctt agggttcgtg catattgcct 60 taatacgcga acgtttaccc tcattgtaca tatagtccct caggtcctct tttaccattt 120 tacgcgttat tctacttcta tcatctgtgt tgtatctgtt tgctagaaga ataccgtccg 180 tgaagagttt caattcaaca aggtcaccct cattacccgt gtgctcaaat 230 <210> 453 <211> 230 <212> DNA <213> Artificial Sequence <400> 453 gacccgctac agtattcaag tcatctacgt ggtgttgctt agggttcgtg catattgcct 60 taatacgcga acgtttaccc tcattgtaca tatagtccct catgtcctct tttaccattt 120 tacgcgtgat tctacttcta tcatctgtgt tgtatctgtt tgctagaaga ataccgtccg 180 tgaagagttt caattcaaca aggtcaccct cattacccgt gtgctcaaat 230 <210> 454 <211> 230 <212> DNA <213> Artificial Sequence <400> 454 tctcatagag gttggtttca ctgttgaacg taacagcgta accctcaaca atcatgtcct 60 cattttcctc aagtgctcta atctcaatgc tacgcgtctc cgatttcatc attagtagcc 120 tccttatttt gattgtttgt ttcacgtgaa acattaatac gtgagcctgt cattctagaa 180 aactgactct cgtctgtttc aggataacca tagtaggcgc gtacctcgtt 230 <210> 455 <211> 230 <212> DNA <213> Artificial Sequence <400> 455 cggagacgcg tagcattgag attagagcac ttgaggaaaa tgaggacatg attgttgagg 60 gttacgctgt tacgttcaac agtgaaacca acctctatga gaccgtatat gaacaaatta 120 gttcaaatgc ttttaatggg gttgacttct cagacgtccg cgcattttat gaccatcaat 180 caggtaactt attaggacga acaaagacag gtaccctaca attaaacaca 230 <210> 456 <211> 230 <212> DNA <213> Artificial Sequence <400> 456 ttaaacctaa gtgggctaca acatacgcac caaacgcaag gtcaggacct tcccttacaa 60 cgcctgtcaa agcaccatca acagatttac gaacaggagc ctataaattt gaggaacgga 120 tagacttcgg tactacgtca gaaaagaacg gacgttatga gttggtaatt ttgacagacg 180 ctaatgtcat attaatgtct aaagccatcc gtgactctga cgcaaaaggc 230 <210> 457 <211> 230 <212> DNA <213> Artificial Sequence <400> 457 agacctaatg actactgtgg cattcagtga gtaccttgat aaaacaggta agaaaattga 60 tttgttactc ctagaggcta actatgacgg tgctgtaatt ggttatagtg aatatatgaa 120 aattcactgc ggttatgata cgtataataa tggttcctat agacatttgt cagttcgcca 180 aaatacagag ttcgccacta aatacttgtc agagggtggt acgagtattc 230 <210> 458 <211> 230 <212> DNA <213> Artificial Sequence <400> 458 ttgaggggtc tgctattagt gactcacgtg gatatgtata cgcctctggt gtgaagtctg 60 agacgttgac gcttgagaaa ttccaagact ttgtagcaaa cacaacaacg ccagttggac 120 agtaaagagg ggtaataccc ctcttttttt gtgcgctata tgatataata ttaatagaac 180 ataacatatt aggaggaatt ataatgatta aattagaact aaaagtaaaa 230 <210> 459 <211> 230 <212> DNA <213> Artificial Sequence <400> 459 gcggttatga tacgtataat aatggttcct atagacattt gtcagttcgc caaaatacag 60 agttcgccac taaatacttg tcagagggtg gtacgagtat tcttttacac cagagtggta 120 gttattactc atatgagaac ctcaaggcgc agaatgggct agacgaaaga catgataagg 180 agtttataca atactgcaaa gaaagaggtt atgattatgt ataagtacgt 230 <210> 460 <211> 230 <212> DNA <213> Artificial Sequence <400> 460 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aataatgggt taattagggt 230 <210> 461 <211> 230 <212> DNA <213> Artificial Sequence <400> 461 accctaatta acccattatt gttgctgaat gcgtctattg tgacggaata tttaactcct 60 gctggcaagt agttggttaa taagtcattg ctataataga ctcttctgtt agttgatgag 120 tcgttaatca acactcgcat gttcccgttt gaatattcta tagtcgcacc atttcctgtc 180 caaccattaa tagtggggtc tttcgagaaa tcatatttca atactaaatt 230 <210> 462 <211> 230 <212> DNA <213> Artificial Sequence <400> 462 tgtacgtgtc cataggtatt tacctttttc tagagttggg atggttgtac tccatcctga 60 tgtaggttca tcaacgcttg aggtattgat tgcccactct gtgttagttg atttgacaga 120 ggcgccagtt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 180 ttgagtatag ttactatatt gacccatata tagcggatat gcgttcgcga 230 <210> 463 <211> 230 <212> DNA <213> Artificial Sequence <400> 463 atttgagcac acgggtaatg agggtgacct tgttgaattg aaactcttca cggacggtat 60 tcttctagca aacagataca acacagatga tagaagtaga atcacgcgta aaatggtaaa 120 agaggacctg agggactata tgtacaatga gggtaaacgt tcgcgtatta aggcaatatg 180 cacgaaccct aagcaacacc acgtagatga cttgaatact gtagcgggtc 230 <210> 464 <211> 229 <212> DNA <213> Artificial Sequence <400> 464 agcaatagtg ctcatcaatg ttacggtaat aaactgtata tgtgttcatt taaattcctc 60 ccctaattta gtgtttgttt aaggtgataa ccacaactaa atcctttttt gtcaattgta 120 tcataataac gtccgtctct ataaaagtgt atacattttt ctctatctaa aagctcaatc 180 tcatgaccaa tttctttgta gaatgctact cgtttcattc catattcat 229 <210> 465 <211> 229 <212> DNA <213> Artificial Sequence <400> 465 tccctcgtag aagtcagcca taattaattg cccaatcacc cctgttagaa aatgacaacg 60 tgggtcatat aacccattaa actctgcacc tgtggcacca accaatgtat taataggcaa 120 ttttacccca attactaaca catacattgg taacgttact tcgttcattg taatctctgt 180 ttcatctgta tatttagcct ctagacgttt ctctaagagt tctttcact 229 <210> 466 <211> 229 <212> DNA <213> Artificial Sequence <400> 466 atgaatatgg aatgaaacga gtagcattct acaaagaaat tggtcatgag attgagcttt 60 tagatagaga aaaatgtata cacttttata gagacggacg tgattatgct acaattgaca 120 aaaaaggttt tagtggtggt tatcacctta aacaaacact aaattagggg aggaatttaa 180 atgaacacat atacagttta ttaccgtaac attgatgagc actattgct 229 <210> 467 <211> 229 <212> DNA <213> Artificial Sequence <400> 467 tttttaatct ctctcacgtc ctctaaacgt gcgtcaatac gctccatggt taattgcatt 60 ttgataaagt tgtcctcatt cattggcatt cgttcccgct cctaactttg attgtatgct 120 agtctatgta tcattttact catgtagtca acttggttct gtaacgtgtc tactgcgtta 180 tcttgagtgc tatatccgtt tagttcataa atgaggtcgt ccatggcta 229 <210> 468 <211> 229 <212> DNA <213> Artificial Sequence <400> 468 ggggataatt atgttagagc aatttaaaac ggagtatatt aacaaggtat taaacggtaa 60 tgggtttgat gatgagttaa atatgctgtt taacagagtt ctagaggagg agttccatgg 120 caacgcgata gccatggacg acctcattta tgaactaaac ggatatagca ctcaagataa 180 cgcagtagac acgttacaga accaagttga ctacatgagt aaaatgata 229 <210> 469 <211> 229 <212> DNA <213> Artificial Sequence <400> 469 tgaggaacta cgcaaagagg ttgcttattg ttggaaagac gtagacgcca ctgagctacg 60 cttctatggt tgtgttgatg ggttacttgc taaagcgttt aattgtgcca tgttcaacct 120 tgataaacaa gcatttaacc aaacaaacgc taatttagta gctcaattaa tgggtgccaa 180 ccgtcctaat agtgtacgtg atgaccttac tgaaccattt acattacct 229 <210> 470 <211> 229 <212> DNA <213> Artificial Sequence <400> 470 taacattgtt gacaaagtca ccaactaaac caattacaat ttttagtagt ggactaataa 60 aattaaggaa gttcatgaac gcttccatga tttgtttacc agactgatta tagaactcgc 120 ttacctgttt gaaaatgcta ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 180 atggataaac cttttcaaac atgatggcgc ccatattcca taataactc 229 <210> 471 <211> 229 <212> DNA <213> Artificial Sequence <400> 471 agtgaacgga attattggcg gtgcaaactg ggttttagaa aaactaggca tggacaagtt 60 aaaaacatgg gaggcacctg aatacgccaa aggtacacca agtggcggtc accctgtaga 120 tggtcccctg actgtcaatg atggacgtgg tgctgaaatg gttattgacc caagtggtca 180 agcggttatc cctaaaggta agaacgtaac gatgtgggga cgaaaagga 229 <210> 472 <211> 229 <212> DNA <213> Artificial Sequence <400> 472 gaaagacccc actattaatg gttggacagg aaatggtgcg actatagaat attcaaacgg 60 gaacatgcga gtgttgttta acgactcatc aacttacaga agagtctatt atagcaatga 120 cttattatcc aactacttgc cagcaggagt taaatattcc gtcacaatag acgcattcag 180 caacaataat gggttaatta gggtaggtaa ttttgacgct ctcagtaca 229 <210> 473 <211> 229 <212> DNA <213> Artificial Sequence <400> 473 actcctattc taggttgtga cctgtaccat gaacacaaag ggttttcact gaaagaacat 60 gagggtttca tggggttaga agtcaaagag acggatgttg actttgaaca aggcggtaaa 120 ctaacagctg aggaactacg caaagaggtt gcttattgtt ggaaagacgt agacgccact 180 gagctacgct tctatggttg tgttgatggg ttacttgcta aagcgttta 229 <210> 474 <211> 229 <212> DNA <213> Artificial Sequence <400> 474 tgtactgaga gcgtcaaaat ttcctaccct aattaaccca ttattgttgc tgaatgcgta 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc aataatagtg gggtctttc 229 <210> 475 <211> 229 <212> DNA <213> Artificial Sequence <400> 475 taacattgtt gacaaagtca ccaactaaac caattacaat ttttagtagt ggactaataa 60 aattaaggaa gttcatgaac gcttccatga tttgtttacc agactgatta tagaactcgc 120 ttacctgatt gaaaatgcta ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 180 atggataaac cttttcaaac atgatggcgc ccatattcca taataactc 229 <210> 476 <211> 229 <212> DNA <213> Artificial Sequence <400> 476 atgaatatgg aatgaaacga gtagcattct acaaagaaat tggtcatgag attgagcttt 60 tagatagaga aaaatgtata cacttttata gagacggacg tgattatgct acaattgaca 120 aaaaaggatt tagtggtggt tatcacctta aacaaacact aaattagggg aggaatttaa 180 atgaacacat atacagttta ttaccgtaac attgatgagc actattgct 229 <210> 477 <211> 228 <212> DNA <213> Artificial Sequence <400> 477 ctagaccaaa cctctacatg ggttcatggg actacagccc ttctgaggcg tttaaaccta 60 agtgggctac aacattcgca ccaaacgcat ggtcaggacc gtcccttaca acgcctgtca 120 aagcaccatc aacaggttta cgaacaggag cctttaaatt tgaggaacgg atagacttcg 180 gtactacgtc agaaaagaac ggacgttatg agttggttat tttgacag 228 <210> 478 <211> 228 <212> DNA <213> Artificial Sequence <400> 478 ccaatgagac gcctgaaact ccgtgagaca cgcacaggta gggaggctgt ttcttactta 60 atgaattgga aacctgattt tacacgttgg gaggacattg agccactatc agtggtgagg 120 gtagacagtg agttaaaaga tgggttctat aatttaggta agcctgaaat tgcaggcaag 180 gttgatgaag ttccaccgcg tcccaataaa ccaagcggga aacaatat 228 <210> 479 <211> 228 <212> DNA <213> Artificial Sequence <400> 479 gacgatgtat taggataaag ggaggaaaac aaaatgagta aagtatttga ggataatttt 60 actaaacccc taccagtggg gacgaaggtg cgcttgatta aacctgaacc aactgaattt 120 tttatgactg agggttacga gcgtgacagg gaatacgttg gagaggtgtt cagagtagct 180 catagcgctg aagaaattga cggacaaacg caccaacttg aactaagt 228 <210> 480 <211> 228 <212> DNA <213> Artificial Sequence <400> 480 gacgtctcta cctaattggg tatttggtaa ttgtagacgg aactttaaac cgctgtcgtc 60 tgtgtttaat tgtagggtac ctgtctttgt tcgtcctaat cagttacctg attgatggtc 120 ataaaatgcg cggacgtctg agaagtcaac cccattaaaa gcatttgaac taatttgttc 180 atatacgttc tcatagaggt tggtttcact gttgaacgta acagcgta 228 <210> 481 <211> 228 <212> DNA <213> Artificial Sequence <400> 481 tgctttatta gtaacacact tgattctgaa ccgcttacag gtgtgtttct agcctgtatt 60 agtgcttcac ctctaattgc attgtgtatg tggcttgatg ataaatagaa tattctcatt 120 aaactctcat ggttttttaa ttgactatta gagtttaatt gtttatacta ggttcataag 180 gttgagggtt aagcctacgg ggtgaacgag taccaaccaa taaagaca 228 <210> 482 <211> 228 <212> DNA <213> Artificial Sequence <400> 482 ggtcataaca aataccttgt acgtctaaat tgtttgtctc aataaacgcc aaaacccaat 60 ttaacatatc ctcccaatca cactgaccgt caggacggga agaaatttca caatacccct 120 gtttggacta ttgtctatag ggtgttctat cgttagcctc tttctgaaca ataccaccac 180 ccgttgttgc tacccacgcg tgagagtcaa caataaacaa ttcttttt 228 <210> 483 <211> 228 <212> DNA <213> Artificial Sequence <400> 483 gacgatgtat taggataaag ggaggaaaac aaaatgagta aagtatttga ggataatttt 60 actaaacccc taccagtggg gacgaaggtg cgcttgatta cacctgaacc aactgaattt 120 tttatgaatg agggttacga gcgtgacagg gaatacgttg gagaggtgtt cagagtagct 180 catagcgctg aagaaattga cggacaaacg caccaacttg aactaagt 228 <210> 484 <211> 228 <212> DNA <213> Artificial Sequence <400> 484 acagatggag caggactcat taaaatgtca gatgaccatg agataatcaa ctatgaaaca 60 gatgacatta tagagttcac aggggtatta cattttgatg aatcacaaga gcagttagtt 120 aaagttatag aaatggcgca gttgggtaat tatctaattt atagacgaca taacggagat 180 agtgcctgtc ttactatcat ggacttcaca cacaacccat tggcggga 228 <210> 485 <211> 228 <212> DNA <213> Artificial Sequence <400> 485 attaggacga acaaagacag gtaccctaca attaaacaca gacgacagcg gtttaaagtt 60 ccgtctacaa ttaccaaata cccaattagg tagagacgtc gatgagttag taaaacgcgg 120 tgacctatca cagtgttcgt ttgggtttat ggttaaaagt gatacgtggt catacaacgc 180 aaacacagac acatatcacc gcacaattga ccaaattggt agattggt 228 <210> 486 <211> 228 <212> DNA <213> Artificial Sequence <400> 486 tataaattat aacacgaaaa agacaaccct agttgggttg cctcgttcgt ttattacagt 60 ccaaaaccaa aatcaccgct tgcgtaacgt tctgaccagt gtatttcctc gaactcataa 120 aagtatgctt cactgtacgc gtttataagc gcgtcaagag ggtcaatctt gttgcggtta 180 acttgtttat caatcataat taaatcgttt gactcttttg taaatgcg 228 <210> 487 <211> 228 <212> DNA <213> Artificial Sequence <400> 487 tgagttaaaa gatgggttct ataatttagg taagcctgaa attgcaggca aggttgatga 60 agttccaccg cgtcccaata aaccaagcgg gaaacaatat gtagtaattt atgatattga 120 ggtatttgag caagattttg tcatttgtgc taaagatttg tttagtggta aacgttggga 180 aattgtcaat gacctagaca aggcgcgtaa atggtattta gaagtacg 228 <210> 488 <211> 228 <212> DNA <213> Artificial Sequence <400> 488 atggtttttt aattgactat tagagtttaa ttgtttatac taggttcata aggttgaggg 60 ttaagcctac tgggtgaact agtaccaacc aataaagaca cgggatggtt aattatgatt 120 aaggtgatga attgggagta tgaatatgga atgaaacgag tagcattcta caaagaaatt 180 ggacatgtga ttgatctgtt agagagagaa aaatgtatac acttttat 228 <210> 489 <211> 228 <212> DNA <213> Artificial Sequence <400> 489 ctagaccaaa cctctacatg ggttcatggg actacagccc ttctgaggcg tttaaaccta 60 agtgggctac aacattcgca ccaaacgcat ggtcaggacc ttcccttaca acgcctgtca 120 aagcaccctc aacaggttta cgaacaggag cctttaaatt tgaggaacgg atagacttcg 180 gtactacgtc agaaaagaac ggacgttatg agttggttat tttgacag 228 <210> 490 <211> 228 <212> DNA <213> Artificial Sequence <400> 490 ccgtgactct gacgcaaaag gcaatgaagt gattgttgaa tactggtacg gtaacaagtt 60 actaaaatct atcaagacag acgtaactaa gtacaaatca acttggttcc gctgtacaat 120 gacacgtgac caaacgggta agaagttcac ttggaacttt gagcatatcc aatcaaacaa 180 cggaattaaa ccagttacaa aaaacccatt tacctacaat gcacctgt 228 <210> 491 <211> 228 <212> DNA <213> Artificial Sequence <400> 491 actggtcaga acgttacgca agcggtgatt ttggttttgg actgtaataa acgaacgagg 60 caacccaact agggttgtct ttttcgtgtt ataatttata tagaagttat aattggagga 120 ggttcaccat ggaacgaatt atatatttac ctatgattat gtatatacta gcgtgtgttt 180 ttatggctat tggtgccttt ttggtagata taaccgtagg ttttatgg 228 <210> 492 <211> 228 <212> DNA <213> Artificial Sequence <400> 492 tgatttgtac ttagttacgt ctgtcttgat agattttagt aacttgttac cgtaccagta 60 ttcaacaatc acttcattgc cttttgcgtc agagtcacgg ttggctatag acattaatat 120 gtcattagcg tctgtcaaaa taaccaactc ataacgtccg ttcttttctg acgtagtacc 180 gaagtctatc cgttcctcaa atttaaaggc tcctgttcgt aaacctgt 228 <210> 493 <211> 228 <212> DNA <213> Artificial Sequence <400> 493 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct atagacaata gtccaaacag gggtattgtg 120 aaatttcgtc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtatttg ttatgacc 228 <210> 494 <211> 228 <212> DNA <213> Artificial Sequence <400> 494 gcgcaagagt ttaaaagtgg tgatagtgat aataaagtag gtacgttctt aggtaaagtt 60 ggggacaagg tatacgaact tgtcaaaggt aaccctcaat gtaaagaggg atatttcaac 120 gatagaacga acgataagta cagatacctt ggtgaatgtg cgtattttca aaacggtgcg 180 ctaaacatgc gtacattaga actacgtccg tttgaaccat gggactat 228 <210> 495 <211> 228 <212> DNA <213> Artificial Sequence <400> 495 ctgtcaaaat aaccaactca taacgtccgt tcttttctga cgtagtaccg aagtctatcc 60 gttcctcaaa tttaaaggct cctgttcgta aacctgttga gggtgctttg acaggcgttg 120 taagggacgg tcctgaccat gcgtttggtg cgaatgttgt agcccactta ggtttaaacg 180 cctcagaagg gctgtagtcc catgaaccca tgtagaggtt tggtctag 228 <210> 496 <211> 228 <212> DNA <213> Artificial Sequence <400> 496 gacgatgtat taggataaag ggaggaaaac aaaatgagta aagtatttga ggataatttt 60 actaaacccc taccagtggg gacgaaggtg cgcttgatta cacctgaacc aactgaattt 120 tttatgactg agggttacga gcgtgacagg gaatacgttg gagaggtgtt cagagtagct 180 catagcgctg aagaaattga cggacaaacg caccaacttg aactaagt 228 <210> 497 <211> 227 <212> DNA <213> Artificial Sequence <400> 497 tggtactttt attacagggc aatcactaga cgagattgaa catttaaaaa attctgacat 60 ttacacagca acaaacatta tcagtggcga tattgctaaa tgtttgatta gagagcgacc 120 ggatggactt gtaagtaaac ctcagattgt aaatatcttg cgtagtaaac cagatacaaa 180 cctaacgtcc tacggttggt tgtatgctat taccatgtat acccttt 227 <210> 498 <211> 227 <212> DNA <213> Artificial Sequence <400> 498 gctttattga ttgtgttcaa cccaatacgt gttaagtggc gagcaatcaa cgcaactaag 60 tcagggtcag agtcttgaat tgcttcgtta gacattggaa tatctccgcg gtgtgtttct 120 accttccatt ctacattttt gaatgttggt tctgccaatt tagggttttc tactaactca 180 gctactgtgt tcattaccgc gttagttgtt tccaaaatag ggtaaga 227 <210> 499 <211> 227 <212> DNA <213> Artificial Sequence <400> 499 gtgacgtttg ggactacgca actaacccaa gcaaattagt tgaaaaagta ttctctagcg 60 tagtagacac ctcaggtctc ataaaatatc ctctagacgg tgcccgtgga atgattaaga 120 aagctactag cgctcttacg tcacgtgtta ctgaggcgtt tgagagcggg agcctagata 180 cgtctgtagg tacagcgggt gtgtataaat accttactaa tgtagcg 227 <210> 500 <211> 227 <212> DNA <213> Artificial Sequence <400> 500 aaagggtata catggtaata gcatacaacc aaccgtagga cgttaggttt gtatctggtt 60 tactacgcaa gatatttaca atctgaggtt tacttacaat tccatccggt cgctctctaa 120 tcaaacagtt agcaatatcg ccactgataa tgtttgttgc tgtgtaaatg tcagaatttt 180 ttaaatgttc aatctcgtct agtgattgcc ctgtaataaa agtacca 227 <210> 501 <211> 227 <212> DNA <213> Artificial Sequence <400> 501 ttacttcgtt tgtatggcgt agatatgacg cctcaaacgt attagacaca tcatggacag 60 caacaggaaa aacaatcaca gtaaatgcag gacaatcaac tgtatataca tattattgtt 120 ctgtagatta ttagaggagg taaaaaacat ggcattagag tcaaagccat tgagtattgc 180 aaacgtacag gatggtcaaa atccattttt acacacagct tacgcat 227 <210> 502 <211> 227 <212> DNA <213> Artificial Sequence <400> 502 ttgattgtcc tgcatttact gtgattgttt ttcctgttgc tgtccatgat gtgtctatta 60 cgtttgaggc gtcatatcta cgccatacaa tcgaagttat attatctgta atgtcttcct 120 tgcctttgac aactttagct gttatactga ttgtaccctc accatttaca aaaaactgtt 180 tagacggtgt aataattacc tcagacggaa tactgttgtc aaactgt 227 <210> 503 <211> 227 <212> DNA <213> Artificial Sequence <400> 503 taccaaccaa caagcctaca aatacgtttt ttacaacgcg tgagagaaca aggcgtcata 60 ggtctcatac taaaggatga actacaggag ttagaaacta tttttcactt gatagacacg 120 ggacacaata gcacgtataa attgccaaaa ttaccagaga ttaaaacata tgacttattt 180 gaggaggatg aatagaatgg aactaacatt acatgatttt gagtata 227 <210> 504 <211> 227 <212> DNA <213> Artificial Sequence <400> 504 gtgacgtttg ggactacgca actaacccaa gcaaattagt tgaaaaagta ttctctagcg 60 tagtagacac ctcaggtctc ataaaatatc ctctagacgt tgcccgtgga atgattaaga 120 aagctacgag cgctcttacg tcacgtgtta ctgaggcgtt tgagagcggg agcctagata 180 cgtctgtagg tacagcgggt gtgtataaat accttactaa tgtagcg 227 <210> 505 <211> 227 <212> DNA <213> Artificial Sequence <400> 505 acattaggta aaataagaaa catgaataaa ggggtcttat gtggggaaca aaacaaatta 60 ttagtagtag actgtgacgt aaaaggtaaa gcaaacggac tacactcttt tactacctta 120 atgaaagact taggacatga aaccatacct aacaccctaa tggtctatac accgtcagga 180 ggcatacact attattttac gttaccagat gacgcactag acctacg 227 <210> 506 <211> 227 <212> DNA <213> Artificial Sequence <400> 506 tgctacaggt gcattgtagg taaatgggtt ttttgtaact ggtttaattc cgttgtttga 60 ttggatatgc tcaaagttcc aagtgaactt cttacccgtg tggtcacgtg tcattgtaca 120 gcggaaccaa gatgatttgt acttagttac gtctgtcttg atagatttta gtaacttgtt 180 accgtaccag tattcaacaa tcacttcatt gccttttgcg tcagagt 227 <210> 507 <211> 227 <212> DNA <213> Artificial Sequence <400> 507 tagcacgtat aaattgccaa aattaccaga gattaaaaca tatgacttat ttgaggagga 60 tgaatagaat ggaactaaca ttacatgatt ttgagtatac cgaggatatg attgacgtat 120 atgatttaga tgatacgtta gtgttttata ctagtgagaa aatagggagt agtacagtca 180 atacacagat tagattagac aagaaggcac aaatggaatt atacaag 227 <210> 508 <211> 227 <212> DNA <213> Artificial Sequence <400> 508 cctgcacgaa tgtgtaggac ttccttagat ttcattgtcc atgttacctt atccactacc 60 tcccttgtgg ctactgagtc tttatacttg agtagccatc tagatgtttt aacaacggaa 120 gctttgtgtg ctacaggtgc attgtaggta aatgggtttt ttgtaactgg tttaattccg 180 ttgtttgatt ggatatgctc aaagttccaa gtgaacttct tacccgt 227 <210> 509 <211> 227 <212> DNA <213> Artificial Sequence <400> 509 gctttcattg acaacctacc agaccccaaa agcggtaaga gggtaggact agcagacttt 60 cagaagttca ttattggtat gatattttca tgggttaaaa aggactcagg gtacaggcga 120 tttactatag tggtaatctc catgagtcgt aagaacggta aatcattatt aatcgcgggt 180 attgcattat atgaacttct ttacgaacgt tcgccaatgg cgtcccg 227 <210> 510 <211> 227 <212> DNA <213> Artificial Sequence <400> 510 cacgtgagat aagttgtgaa gatggtgcac ttgacttact taataatgtt gtacctgcta 60 ttaaaaccac gtcacctcaa tcgtttcaat actactggac cattgtcatg agagacacgg 120 gctttacatt gggcgcaaac tactttagta atcagacacg tactttaaac tatgataatg 180 agacaacagc agtggagcgt ctaaggagta ttatttcaga ctttgga 227 <210> 511 <211> 227 <212> DNA <213> Artificial Sequence <400> 511 cgggacgcca ttggcgaacg ttcgtaaaga agttcatata atgcaatacc cgcgattaat 60 aatgatttac cgttcttacg actcatggag attaccactt tagtaaatcg cctgtaccct 120 gagtcctatt taacccatga aaatatcata ccaataatga acttctgaaa gtctgctagt 180 cctaccctct taccgctttt ggggtctggt aggttgtcaa tgaaagc 227 <210> 512 <211> 227 <212> DNA <213> Artificial Sequence <400> 512 agaagatata ttggaaaaag gtaaacgata taccattgtt ggagtaggca gccttttcgt 60 gcaggttgat ggtattgatg aatggttcta ctatgaccgg tttgaacgtg actatgttaa 120 tgagggaatt gaatatagtt tgaaagataa acatggtgct accttgagtg tcgctaggtt 180 atataaagat aaaacagtga ttaaaattac tgattttacg aatgatg 227 <210> 513 <211> 227 <212> DNA <213> Artificial Sequence <400> 513 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagt gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactaatg cttttagtat acagggtaat tcaaatg 227 <210> 514 <211> 227 <212> DNA <213> Artificial Sequence <400> 514 ttatttttga ctgagttaca ttcacattgg ctaaatgtgg gtgcatggtt ttgaacatat 60 caaacgtaag ccacgtagga gcctcatagc cctctctaat tcgttcaaag gtaacttgta 120 cctcatccca tttagaacac ctctgagcgt ctctatacgc ctttatttga acatccaaag 180 cgtcctcacc ctcttttagt attcctctga gatgttttat cttatcc 227 <210> 515 <211> 227 <212> DNA <213> Artificial Sequence <400> 515 gctttcattg acaacctacc agaccccaaa agcggtaaga gggtaggact agcagacttt 60 cagaagttca ttattggtat gatattttca tgggttaaat aggactcagg gtacaggcga 120 tttactatag tggtaatctc catgagtcgt aagaacggta aatcattatt aatcgcgggt 180 attgcattat atgaacttct ttacgaacgt tcgccaatgg cgtcccg 227 <210> 516 <211> 227 <212> DNA <213> Artificial Sequence <400> 516 atcaatcata attaaatcga ttgactcttt tgtaaatgcg ttgtacacgg ctcttgtcaa 60 tagagggttg ttaaagtgaa ggaccttgcc cgctcgtata tccacttgta attgtttagt 120 aggtgggatt aatcgcatat aagactgacg tacatcaaag agtacgtcct catacccgtc 180 tgctagtctt gtggtaatta attgagactg tgcagggtca taacaaa 227 <210> 517 <211> 227 <212> DNA <213> Artificial Sequence <400> 517 caaggttacc taaatcattt ttagcaatct taacaataac aaactcatcc tcaacttcat 60 cctgttcccc atccacgcgt atagtcactt tcttttctag ttcttgctcc tgtaaacgca 120 ttccctccgc gcgtactttc tcatattgct gtactgcctc cattaggtct aaaccgttgt 180 ttgcatatac agctagaata gaggttcgtt ggttgcgtat agggtac 227 <210> 518 <211> 227 <212> DNA <213> Artificial Sequence <400> 518 agaagatata ttggaaaaag gtaaacgata taccattgtt ggagtaggca gccttttcgt 60 gcaggttgat ggtattgatg aatggttcta ctatgaccgg tttgaacgtg actatgttaa 120 tgagggactt gaatatagtt tgaaagataa acatggtgct accttgagtg tcgctaggtt 180 atataaagat aaaacagtga ttaaaattac tgattttacg aatgatg 227 <210> 519 <211> 227 <212> DNA <213> Artificial Sequence <400> 519 gtgacgtttg ggactacgca actaacccaa gcaaattagt tgaaaaagta ttctctagcg 60 tagtagacac ctcaggtctc ataaaatatc ctctagacgg tgcccgtgga atgattaaga 120 aagctacgag cgctcttacg tcacgtgtta ctgaggcgtt tgagagcggg agcctagata 180 cgtctgtagg tacagcgggt gtgtataaat accttactaa tgtagcg 227 <210> 520 <211> 227 <212> DNA <213> Artificial Sequence <400> 520 aaagggtata catggtaata gcatacaacc aaccgtagga cgttaggttt gtatctggtt 60 tactacgcaa gatatttaca atctgaggtt tacttacaag tccatccggt cgctctctaa 120 tcaaacagtt agcaatatcg ccactgataa tgtttgttgc tgtgtaaatg tcagaatttt 180 ttaaatgttc aatctcgtct agtgattgcc ctgtaataaa agtacca 227 <210> 521 <211> 226 <212> DNA <213> Artificial Sequence <400> 521 taccacgctt tgagttgcct gtagtcactg tcaaatcgtt caaagaatga ggtaagggac 60 tcatttattt ttgactgagt tacattcaca ttggctaaat gtgggtgcat ggttttgaac 120 atatcaatcg taagccacgt aggagcctca tagccctctc tacatcgttc aaaggtaact 180 tgtacctcat cccatttaga acacctctga gcgtctctat acgcct 226 <210> 522 <211> 226 <212> DNA <213> Artificial Sequence <400> 522 taaggagttt atacaatact gcaaagaaag aggttatgat tatgtataag tacgtagtac 60 gctacaaaga ctttgatggt tcatacgtgt attttactgc attttcctca aggtcaccga 120 tttatgagga ggaaagagga cgcacaaggt ttagacagat tgtcactgat aaaccgcgtc 180 taaaaatgga cataacaacc gctaaaatgg ttagggacct aactgg 226 <210> 523 <211> 226 <212> DNA <213> Artificial Sequence <400> 523 ttaacttaat gattagtaca acctcacaaa acctaaacgg acactatcat atggaggaat 60 atccaatgac tatgaaagta ttaacaggtg aggtagaggc tgaacactac ttagctctat 120 ggtgggacat ggatagtttt gacgaggcgg atgacgagga aaactggttt aaatctaacc 180 ctctttttga aaaacctgac gttcgcacac atatgttaga acacaa 226 <210> 524 <211> 226 <212> DNA <213> Artificial Sequence <400> 524 cgcggatatt atcaagtggg taattcagac ggtcagaacc tacaatatac aagaataggc 60 aataacacgc ttacttttga tggacacttg attacagaac actcaggact ttctattagt 120 gagacaatag atttactagt tgcacaagta atgagtaggg aacctatgaa actagtgttt 180 gacgcattac ctgatagata ttttaacgta gtgtttgagg gcacgc 226 <210> 525 <211> 226 <212> DNA <213> Artificial Sequence <400> 525 cccgcaagca ttgtactaaa tgcctcatct gctgtatatc ccatttgtgc ccaaatagga 60 gcatactccg ctaagttatc cgctagttcg tcagatttat taagtccgtt ttgtgcgcct 120 aacgtcagta ggtcaaacgc ttgcttacta tctagacccc acgagttcat aatggcgccc 180 gcaccgcgta gggtttcatt tacgtctgta tcaaacatct ttgaaa 226 <210> 526 <211> 226 <212> DNA <213> Artificial Sequence <400> 526 tcctcgaact cataaaagta tgcttcactg tacgcgttta taagcgcgtc aagagggtca 60 atcttgttgc ggttaacttg tttatcaatc ataattaact cgtttgactc ttttgtaaat 120 gcgttgtaca cggctcttgt caatagaggg ttgttaaagt gaaggacctt gcccgctcgt 180 atatccactt gtaattgttt agtaggtggg tttaatcgca tataag 226 <210> 527 <211> 226 <212> DNA <213> Artificial Sequence <400> 527 tatactacta ttgacaaacc aattcacaca ctctggcgga tagcctagca caattccaag 60 tgcataatct tctccgtgtt ttcttgacaa tttagaaaac tcatccaatt gctctaactt 120 ggagacacca agcatgccac tatatacgta agttgtgaag tgttccctta caatatttgt 180 aagttctgac accctaataa agatggcgtc tctcagtccc aaatta 226 <210> 528 <211> 226 <212> DNA <213> Artificial Sequence <400> 528 tgtacgcctt ttcccactcg tctacagaaa tgtatgacgt tgcttggtcc gcaacccaaa 60 aattaagctc cttagttagg aagttggtga gattaccttt agcctctccc tctgtctttt 120 tagcccggtt gtgttctatc atatgtgtgc gaacgtcagg tttttcaaaa agagggttag 180 atttaaacca tttttcgtcg tcatcagcct cgtcaaaact atccat 226 <210> 529 <211> 226 <212> DNA <213> Artificial Sequence <400> 529 acctcctcca attataactt ctttataaat tataacacga aaaagacaac cctagttggg 60 ttgcctcgtt cgtttattac agtccaaaac caaaatcacc gcttgcgtaa cgttctgacc 120 agtttatgtc ctcgaactca taaaagtatg cttcactgta cgcgtttata agcgcgtcaa 180 gagggtcaat cttgttgcgg ttaacttgtt tatcaatcat aattaa 226 <210> 530 <211> 226 <212> DNA <213> Artificial Sequence <400> 530 ggtaatgtca tcaagtagtt tatcatattg cgcaaactca atagatggta catcacctac 60 gtaaatcatc aactcgttat ccaataatta caccgtcctc atttactgct acaacctcac 120 catatccccc agttaggtcc ctaaccattt tagcggttgt tatgtccatt tttagacgcg 180 gtttatcagt gacaatctgt ctaaaccttg tgcgtcctct ttcctc 226 <210> 531 <211> 226 <212> DNA <213> Artificial Sequence <400> 531 tttctactaa ctcagctact gtgttcatta ccgcgttagt tgtttccaaa atagggtaag 60 aacctgacgt tgtgctaact gttactacgt tgatatagat ttgtaggtct acgattgtct 120 caggtaatgt tacaggttga gtaatgcggt caaccggaac aattgcctca acgccctcta 180 atttaatatc ccgtaactca ggtgctttta cagaaccgtg tgagcg 226 <210> 532 <211> 226 <212> DNA <213> Artificial Sequence <400> 532 gagccaacct cactatgatt tagattatgt gtttcccatt tgtctatgac catttgctgt 60 tgttccgttg gtattaacat tatattacct cctccacaat agtctatcat gaaaccatgt 120 agggttgttg tgttgggtag taggttatat tttgttatta ttgtacacat tcaaaaaccg 180 tgtacacttt ttgtacaaac ctgttttacg ccttgtgtat caatgt 226 <210> 533 <211> 226 <212> DNA <213> Artificial Sequence <400> 533 taggtcaaac gcttgcttac tatctagacc ccacgagttc ataatggcgc ccgcaccgcg 60 tagggtttca tttacgtctg tatcaaacat ctttgaaatc gataccgcgt aacgtgtaag 120 gttctgtagg tcctcaccga atacagggat agggctgttt tgctcaaccc tactcatagc 180 gtcaaccatt tcctcaaggc tacccaaacc ctcagcaact agttcg 226 <210> 534 <211> 226 <212> DNA <213> Artificial Sequence <400> 534 caacatagac aacgaacgca agcgggttaa aaaagaaatt ttacgaccct atgacgagct 60 agaggataag ataaaacatc tcagaggaat actaaaagag ggtgaggacg ctttggatgt 120 tcaaatacag gcgtatagag acgctcagag gtgttctaaa tgggatgagg tacaagttac 180 ctttgaacga tttagagagg gctatgaggc tcctacgtgg cttacg 226 <210> 535 <211> 226 <212> DNA <213> Artificial Sequence <400> 535 tagcatgttt gtagatgtac tttgtgtgtt tctaaatggg tcacttaaaa tagagtgtgc 60 cacaccctca gggcatgaaa atgttaacgt caacggtgta atgtctaaat tagttgcgtc 120 atactctagc gtgccctcaa acactacgtt aaaatatcta tcaggtaatg cgtcaaacac 180 tagtttcata ggttccctac tcattacttg tgcaactagt aaatct 226 <210> 536 <211> 226 <212> DNA <213> Artificial Sequence <400> 536 tgtttgctac aaagtcttgg aatttctcaa gcgtcaacgt ctcagacttc acaccagagg 60 cgtatacata tccacgtgag tcactaatag cagacccctc aaaagtatca gtattagggt 120 cagtgcctcc accctctgag gtattcaacg caacgtcagg gtgagcaaag cgaactttag 180 tcagtcccat atatacctca ttaccatctg cgtcatctga tacaca 226 <210> 537 <211> 226 <212> DNA <213> Artificial Sequence <400> 537 ctatatcaac gtagtaacag ttagcacaac gtcaggttct taccctattt tggaaacaac 60 taacgcggta atgaacacag tagctgagtt agtagaaatc cctaaattgg cagaaccaac 120 attcaaaaat gtagaatgga aggtagaaac acaccgcgga tatattccaa tgtctaacga 180 agcaattcaa gactctgacc ctgacttagt tgcgttgatt gctcgc 226 <210> 538 <211> 226 <212> DNA <213> Artificial Sequence <400> 538 atggatagtt ttgacgaggc ggatgacgag gaaaactggt ttaaatctaa ccctcttttt 60 gaaaaacctg acgttcgcac acatatgtta gaacacaaac gggctaaaaa gacagaggga 120 gaggctacag gtaatctcac caacttccta actaaggagc ttaatttttg ggttgcggac 180 caagcaacgt catacatttc tgtagacgag tgggaaaagg cgtaca 226 <210> 539 <211> 226 <212> DNA <213> Artificial Sequence <400> 539 caagcatgcc actatatacg taagtagtga agtgttccct tacaatattt gtaagttctg 60 acaccctaat aaagatggcg tctctcagtc ccaaattata tgccacagtt tcttctagta 120 aaatattcat ggtgacctct cctctttacc cctcatgtct ctcattaaca acataatcaa 180 agtcacttgc aaatagcgga atcattagtt ctccatcaac gtcaca 226 <210> 540 <211> 226 <212> DNA <213> Artificial Sequence <400> 540 tgtacgcctt ttcccactcg tctacagaaa tgtatgacgt tgcttggtcc gcaacccaaa 60 aattaagctc cttagttagg aagttggtga gattacctgt agcctctccc tctgtctttt 120 tagcccggtt gtgttctaac atatgtgtgc gaacgtcagg tttttcaaaa agagggttag 180 atttaaacca gttttcctcg tcatccgcct cgtcaaaact atccat 226 <210> 541 <211> 225 <212> DNA <213> Artificial Sequence <400> 541 tatgattgtt tttgatgagt ctcactgtct agcaaacagg agcgcaaacg taactaagtt 60 ttggatgaaa gtaagtaaga aagcaggaca cacctattta atgagcggaa ctccaatttc 120 taacggactg ttagaacaat ggttttctca attgaaaatc gcaggtttat actctggaac 180 gtggaaatct tttagagaac gctactgtat agaagagaaa cagta 225 <210> 542 <211> 225 <212> DNA <213> Artificial Sequence <400> 542 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct atagacacta ttccaaacag gggtattgtg 120 aaatttcttc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtatttg ttatg 225 <210> 543 <211> 225 <212> DNA <213> Artificial Sequence <400> 543 ttttgtcaaa gaagccagta ccttttttgt atgcaaactt aggacgttta tgacctaaca 60 cttgtgcagt ttcttctgct gttaaaacgt gggttccatt tcgtccccac atcgttacgt 120 tcttaccttt agggataacc gcttgaccac ttgggtcaat aaccatttca gcaccacgtc 180 catcattgac agtcatggga ccatctacag ggtgaccgcc acttg 225 <210> 544 <211> 225 <212> DNA <213> Artificial Sequence <400> 544 gcgttgccat ggaactcctc ctctagaact ctgttaaaca gcatatttaa ctcatcatca 60 aacccattac cgtttaatac cttgttaata tactccgatt taaattgctc taacataatt 120 atccccctta gaataaatct tgacccgcat atacgcaaga gatgtttatc catgcgcctg 180 acggaatcgc actatctact gtagtaccat acctacttac tagaa 225 <210> 545 <211> 225 <212> DNA <213> Artificial Sequence <400> 545 caagtggcgg tcaccctgta gatggtccca tgactgtcaa tgatggacgt ggtgctgaaa 60 tggttattga cccaagtggt caagcggtta tccctaatgg taagaacgta acgatgtggg 120 gacgaaaagg aacccacgtt ttaacagcag aagaaactgc acaagtgtta ggtcataaac 180 gtcctaagtt tgcatacaaa aaaggtactg gcttctttga caaaa 225 <210> 546 <211> 225 <212> DNA <213> Artificial Sequence <400> 546 tatacacaat atctgatggg atgagtttgt tgtcacgttt aatagcaacg ctgtgttctt 60 tgagtagctc atttaattcc tcagtgtttc tatatcccac aatcgcatta taagaccgtc 120 cacctaacta ctgtttctct tctatacagt agcgttctct aaaagatttc cacgttccag 180 agtataaacc tgcgattttc aattgagaaa accattgttc taaca 225 <210> 547 <211> 225 <212> DNA <213> Artificial Sequence <400> 547 gggtttcatt tacgtctgta tcaaacatct ttgaaaacga taccgcgtaa cgtgtaaggt 60 tctgtaggtc ctcaccgaat acagggatag ggctgttgtg ctcaacccta ctcatagcgt 120 caaccatttc ctcaaggcta cccaaaccct cagcaactag ttcgttagcc atttgagtgt 180 agttttctgc gccctcttgt gaaagaccta atgcaccttg aaact 225 <210> 548 <211> 225 <212> DNA <213> Artificial Sequence <400> 548 ataagataaa acatctcaga ggaatactaa aagagggtga ggacgctttg gatgttcaaa 60 taaaggcgta tagagacgct cagaggtgtt ctaaatggga tgaggtacaa gttacctttg 120 aacgattgag agagggctat gaggctccta cgtggcttac gtttgatatg ttcaaaacca 180 tgcacccaca tttagccaat gtgaatgtaa ctcagtcaaa aataa 225 <210> 549 <211> 225 <212> DNA <213> Artificial Sequence <400> 549 ccttatcgcg acaataggtt aatggataaa tgtcttttac ttctggtgtc atttctgtgt 60 gtattgtagg aatcatcatg cctgttttct cctttcgttc ttcgtttatt atgttagcat 120 actttttccg tcagcgcaag gggtaacttg atggggacac cttgttgggg tacattttga 180 tgataataat taaataacaa aaataataaa ataacaaagg gtggt 225 <210> 550 <211> 225 <212> DNA <213> Artificial Sequence <400> 550 tacgctatcg cattgaggat gtttcacgtg gaacatacag caaagacttt gatactttga 60 ttgctaagga ggtttctaaa gaggacgttt taaatgaggt ggtaaaatga gtgataatta 120 tgtagacgtt agtgacatct acaaagcgct tggtgaacta ggtaaagact tagaccgtga 180 ggcaaataaa ataatgaacg acatagcgcc tgaggttgct gagga 225 <210> 551 <211> 225 <212> DNA <213> Artificial Sequence <400> 551 ccttatcgcg acaataggtt aatggataaa tgtcttttac ttctggtgtc atttctgtgt 60 gtattgtagg aatcatcatg cctgttttct cctttcggtc ttcgtttatt atgttagcat 120 actttttacg tcagcgcaag gggtaacttg atggggacac cttgttgggg tacattttga 180 tgataataat taaataacaa aaataataaa ataacaaagg gtggt 225 <210> 552 <211> 225 <212> DNA <213> Artificial Sequence <400> 552 cataacaaat accttgtacg tctaaattgt ttgtctcaat aaacgccaaa acccaattta 60 acatatcctc ccaatcacac tgaccgtcag gacgggacga aatttcacaa tacccctgtt 120 tggaatagtg tctatagggt gttctatcgt tagcctcttt ctgaacaata ccaccacccg 180 ttgttgctac ccacgcgtga gagtcaacaa taaacaattc ttttt 225 <210> 553 <211> 225 <212> DNA <213> Artificial Sequence <400> 553 gggtttcatt tacgtctgta tcaaacatct ttgaaaacga taccgcgtaa cgtgtaaggt 60 tctgtaggtc ctcaccgaat acagggatag ggctgttgtg ctcaacccta ctcatagcgt 120 caaccatgtc ctcaaggcta cccaaaccct cagcaactag ttcgttagcc atttgagtgt 180 agttttctgc gccctcttgt gaaagaccta atgcaccttg aaact 225 <210> 554 <211> 225 <212> DNA <213> Artificial Sequence <400> 554 ttctagtaag taggtatggt actacagtag atagtgcgat tccgtcaggc gcatggataa 60 acatctcttg cgtatatgcg ggtcaagatt tattctatgg gggataatta tgttagagca 120 atttaaatcg gagtatatta acaaggtatt aaacggtaat gggtttgatg atgagttaaa 180 tatgctgttt aacagagttc tagaggagga gttccatggc aacgc 225 <210> 555 <211> 225 <212> DNA <213> Artificial Sequence <400> 555 caagtggcgg tcaccctgta gatggtccca tgactgtcaa tgatggacgt ggtgctgaaa 60 tggttattga cccaagtggt caagcggtta tccctaatgg taagaacgta acgatgtggg 120 gacgaaatgg aacccacgtt ttaacagcag aagaaactgc acaagtgtta ggtcataaac 180 gtcctaagtt tgcatacaaa aaaggtactg gcttctttga caaaa 225 <210> 556 <211> 225 <212> DNA <213> Artificial Sequence <400> 556 ccttatcgcg acaataggtt aatggataaa tgtcttttac ttctggtgtc atttctgtgt 60 gtattgtagg aatcatcatg cctgttttct cctttcggtc ttcgtttatt atgttagcat 120 actttttccg tcagcgcaag gggtaacttg atggggacac cttgttgggg tacattttga 180 tgataataat taaataacaa aaataataaa ataacaaagg gtggt 225 <210> 557 <211> 224 <212> DNA <213> Artificial Sequence <400> 557 agggtgtcat acgttacagc acgtgtgaac aaacctcctg ttgttgataa gagtctggac 60 catttaggag cttcttgcgt gtcaatcata accccagtct caagtttaaa acgcccatct 120 gggtcaaccc acgagaaccc acttaatgta ttggggttgt ttgacccctc tggtgtacca 180 cctaatgctc gtattgctgt agttaactca taaatgttac ctgt 224 <210> 558 <211> 224 <212> DNA <213> Artificial Sequence <400> 558 tacacctaca gtagacaata ctagccctac atatgtaggg tatagtacca cggacactgt 60 acctgaggac actgcgccaa atatcctatt aaacggttca caggacaata gtatacagta 120 ttggggactc tttgacgcag taacggctac accaacagca ggagccacta aattaactaa 180 aacagcagtg tcaacaatac gtcctgcata cctatcaaat ggct 224 <210> 559 <211> 224 <212> DNA <213> Artificial Sequence <400> 559 acacaaccta caaccttgac aaaactaaag gcggtgcaat tgaggcaaca atcagtggac 60 taggagcgga ggctactaca gtctacgcgt caaacggtcc gtttttcgta tctgctaaag 120 gtacaggtga aacaaccgta tcattgaatg ttttcgactt acaagcgggt ggagcatata 180 gtgctgtttt aggtattacc gcagacgaaa atggtattat gaca 224 <210> 560 <211> 224 <212> DNA <213> Artificial Sequence <400> 560 gcgcctctag ttcctgttca ttatctagag catgaccaat tttacagagc agtgtgtggc 60 gcattagttc taattcttta cgcagtggtc tattcagtgt ctcactggcg tcaaacatat 120 tagaggcatg aaataaattg tcataacaat tattcaatgt gtccccatct ttaaagccca 180 caaatttatc attacccaca ttgggaacaa acatatctgc cacc 224 <210> 561 <211> 224 <212> DNA <213> Artificial Sequence <400> 561 ataataaagt aggtacgttc ttaggtaaag ttggggacaa ggtatacgaa cttgtcaaag 60 gtaaccctca atttaaagag ggatatttca acgatagaac gaacgataag tacagatacc 120 ttggtgactg tgcgtatttt caaaacggtg cgctaaacat gcgtacatta gaactacgtc 180 cgtttgaacc atgggactat agaacgcaag acaccatttt accc 224 <210> 562 <211> 224 <212> DNA <213> Artificial Sequence <400> 562 tggatagttt tgacgaggcg gatgacgagg aaaactggtt taaatctaac cctctttttg 60 aaaaacctga cgttcgcaca catatgttag aacacacacg ggctaaaaag acagagggag 120 aggctaaagg taatctcacc aacttcctaa ctaaggagct taatttttgg gttgcggacc 180 aagcaacgtc atacatttct gtagacgagt gggaaaaggc gtac 224 <210> 563 <211> 224 <212> DNA <213> Artificial Sequence <400> 563 ccgtgtttcc tagttcgatt tttatttttg ttatagttat aattaaagca tttgaattac 60 cctgtatact aaaagcatta gttgcccctg cggttagacc ctcaaattta tacgttgaag 120 gtgtgtcacc ttgttttatt gtttgccatg tactgagagc gtcaaaatta cctaccctaa 180 ttaacccatt attgttgctg aatgcgtcta ttgtgacgga atat 224 <210> 564 <211> 224 <212> DNA <213> Artificial Sequence <400> 564 atcttcacaa cttatctcac gtgttcccgc caatgggttg tgtgtgaagt ccatgatagt 60 aagacaggca ctatctccgt tatgtcgtct ataaattaga taattaccca actgcgccat 120 ttctttatct ttaactaact gctcttgtga ttcatcaaaa tgtaataccc ctgtgaactc 180 tataatgtca tctgtttcat agttgattat ctcatggtca tctg 224 <210> 565 <211> 224 <212> DNA <213> Artificial Sequence <400> 565 acacaaccta caaccttgac aaaactaaag gcggtgcaat tgaggcaaca atcagtggac 60 taggagcgga ggctactaca gtctacgcgt caaacgttcc gtttttcgta tctgctaaag 120 gtacaggaga aacaaccgta tcattgaatg ttttcgactt acaagcgggt ggagcatata 180 gtgctgtttt aggtattacc gcagacgaaa atggtattat gaca 224 <210> 566 <211> 224 <212> DNA <213> Artificial Sequence <400> 566 gcccactctg ttttagttga tttgacagag gcgccatttt gtcccgttgt tctcatccac 60 gtgtacttac ttgggtccgt gctaggttct tgagtagagt tactatattg acccatatat 120 agcggatatg cgttcgcgaa atcttcagat gggtttgggg tgtagatggt tgccgtgttt 180 cctagttcga tttttatttt tgttatagtt ataattaaag catt 224 <210> 567 <211> 224 <212> DNA <213> Artificial Sequence <400> 567 tactcaagaa cctagcacgg acccaagtaa gtacacgtgg atgagaacaa cgggacaaaa 60 tggcgcctct gtcaaatcaa ctaaaacaga gtgggccatc aatacctcaa gcgttgatga 120 acctacatca ggatggagta caaccatccc aactctagaa aaaggtaaat acctatggac 180 acgtacaacg tgggagtaca ctgatggtac aacatcagta gcct 224 <210> 568 <211> 224 <212> DNA <213> Artificial Sequence <400> 568 atcttcgcgc gtactatcat agtaggtaac acgcacaatt aattctgttg ttgctagact 60 accagtccac cccttagaga tgaatacact ccctgataca gtgtacgttg taccgcgcaa 120 agcactggag ccatttgata ggtatgcagg acgtattgtt gacactgctg ttttagttaa 180 tttagtggct cctgctgttg gtgtagccgt tactgcgtca aaga 224 <210> 569 <211> 224 <212> DNA <213> Artificial Sequence <400> 569 tagacgcatg accctatgaa ctcacataat gctttatcac ttcgtgggtc agtaaagaag 60 ttgaccgctt gccatagtct atttttctca atctctggta gcgtcacagg tgtctctttt 120 acatgcaggg gtaaaatggt gtcttgcgtt ctatagtccc atggttcaaa cggacgtagt 180 tctaatgtac gcatgtttag cgcaccgttt tgaaaatacg caca 224 <210> 570 <211> 224 <212> DNA <213> Artificial Sequence <400> 570 atattccgtc acaatagacg cattcagcaa caataatggg ttaattaggg taggtaattt 60 tgacgatctc attacatcgc aaacaataaa acaacgagac acaccttaaa cgtataaatt 120 tgagggtata accgcagtgg caactaatgc ttttagtata cagggtaatt caaatgcttt 180 aattataact ataacaaaaa taaaaatcga actaggaaac acgg 224 <210> 571 <211> 224 <212> DNA <213> Artificial Sequence <400> 571 ttaaccgcgt tacctactga cccactgctt ataatcttat attcaatcat ctaatcacac 60 ccaatcatac tctgtttgtt cttctgaatt gtcgttctct aggttccata atagtttacc 120 taatcgtagc gcctctagtt cctgttcatt atctagagca tgaccaattt tacagagcag 180 tgtgtggcgc attagttcta attctttacg cagtggtcta ttca 224 <210> 572 <211> 224 <212> DNA <213> Artificial Sequence <400> 572 ttattatggt ataattaata aagaaacaag tgtaaggggg gtttttaaaa tagaatttta 60 ttttactgat agggaattta accctatagg aattgcgtcc acagatggag caggactcat 120 taaaatgaca gatgaccatg agataatcaa ctatgaaaca gatgacatta tagagttcac 180 aggggtatta cattttgatg aatcacaaga gcagttagtt aaag 224 <210> 573 <211> 224 <212> DNA <213> Artificial Sequence <400> 573 gcaactaatg agggtgctac acagaggaca gacggtaata cacctacagt agacaatacg 60 agccctacat atggagggta tagtaccacg gacactgtac ctgaggacac tgcgccaaat 120 atcctattca acggttcaca ggacaatagt atacagtatt ggggaatctt tgacgcagta 180 acggctacac caacagcagg agccactaaa ttaactaaaa cagc 224 <210> 574 <211> 224 <212> DNA <213> Artificial Sequence <400> 574 acacaaccta caaccttgac aaaactaaag gcggtgcaat tgaggcaaca atcagtggac 60 taggagcgga ggctactaca gtctacgcgt caaacggtcc gtttttcgta tctgctaaag 120 gtacaggaga aacaaccgta tcattgaatg ttttcgactt acaagcgggt ggagcatata 180 gtgctgtttt aggtattacc gcagacgaaa atggtattat gaca 224 <210> 575 <211> 224 <212> DNA <213> Artificial Sequence <400> 575 ccgtgtttcc tagttcgatt tttatttttg ttatagttat aattaaagca tttgaattac 60 cctgtatact aaaagcatta gttgcccctg cggttagacc ctcaaattta tacgttgaag 120 gtgtgtctcc ttgttttatt gtttgccatg tactgagagc gtcaaaatta cctaccctaa 180 ttaacccatt attgttgctg aatgcgtcta ttgtgacgga atat 224 <210> 576 <211> 223 <212> DNA <213> Artificial Sequence <400> 576 gtagtattga aacgattgag gtgacgtggt tttaatagca ggtacaacat tattaagtaa 60 gtcaagtgca ccatcttcac aacttatctc acgtggtccc gccaatgggt tgtgtgtgaa 120 gtccatgata gtaagacagg cactatctcc gttatgtcgt ctataaatta gataattacc 180 caactgcgcc atttctttaa ctttaactaa ctgctcttgt gat 223 <210> 577 <211> 223 <212> DNA <213> Artificial Sequence <400> 577 agcaccaacc tcacaacttc tataacgcgt tctacaccct gtaagtgttc agcaatctca 60 cacgcctcaa aaatatcatt ggcaaaaata agacagtcct catacttcat acgccaacta 120 atgtacgtca ctctaaacat tatacatcac tcctgttcta atttctaaga cctcaattcc 180 taacacttgt tctaaggcaa caaactctgt cttatactgg tta 223 <210> 578 <211> 223 <212> DNA <213> Artificial Sequence <400> 578 tccgctgtac aatgacacgt gaccaaacgg gtaagaagtt cacttggaac tttgagcata 60 tccaatcaaa caacggaatt aaaccagtta caaaaaaccc atttacctac actgcacctg 120 tagcaaacaa agcttccgtt gttaaaacat ctagatggct actcaagtat aaagactcag 180 tagccacaag ggaggtagtg gataaggtaa catggacaat gaa 223 <210> 579 <211> 223 <212> DNA <213> Artificial Sequence <400> 579 tctcatagac gcatgaccct atgaactcac ataatgcttt ttcacttagt gggtcagtaa 60 agaagttgac cgcttgccat agtctatttt tctcactctc tggtagcgtc acaggtgtct 120 cttttacatg aatgggtaaa atggtgtctt gcgttctata gtcccatggt tcaaacggac 180 gtagttctaa tgtacgcatg tttagcgcac cgttttgaaa ata 223 <210> 580 <211> 223 <212> DNA <213> Artificial Sequence <400> 580 tcaatgatgg acgtggtgct gaaatggtta ttgacccaag tggtcaagcg gttatcccta 60 aaggtaagaa cgtaacgatg tggggacgaa aaggacccca cgttttaaca gcagaagaaa 120 ctgcacaagt gttaggtcat aaacgtccta agtttgcata caaaaaaggt actggcttct 180 ttgacaaaat tacaggaggc gtaaaaaaca tctggaacgg tgc 223 <210> 581 <211> 223 <212> DNA <213> Artificial Sequence <400> 581 ctgtagtagc ctccgctcct agtccactga ttgttgcctc aattgcaccg cctttagttt 60 tgtcaaggtt gtaggttgtg tagcctgtac cctcgttatt gggcacatga atatgagcag 120 atttaaatcc gatttttgcc atgtttgtgt catcctttct tgtctttctt atattatttt 180 aacacatgat tttcgttcaa agttagacta gctttatgtc tct 223 <210> 582 <211> 223 <212> DNA <213> Artificial Sequence <400> 582 acgcgagtag gtagaacggt tcaaatagca ggtgcgttta aacccataaa ccaacttagc 60 gcaggtcaat atgtcattaa ccaacctcta ccagtgtggg ctagaccatt gaataacgta 120 acactcattc atcaaggttc tggaatgaac aggctactac tagaagtgcg caaggatggt 180 gcaattctag taagtaggta tggtactaca gtagatagtg cga 223 <210> 583 <211> 223 <212> DNA <213> Artificial Sequence <400> 583 tgaattaccc tgtatactaa aagcattagt tgcccctgcg gttataccct caaatttata 60 cgttgaaggt gtgtcacctt gttttattgt ttgccatgta ctgagagcgt caaaattacc 120 taccctactt aacccattat tgttgctgaa tgcgtctatt gtgacggaat atttaactcc 180 tgctggcaag tagttggtta ataagtcatt gctataatag act 223 <210> 584 <211> 223 <212> DNA <213> Artificial Sequence <400> 584 tgtcttattt ttgccaatga tattttggag gcgtgtgaga ttgctgaaca cttacagggt 60 gtagaacgcg ttatagaagt tgagaggttg gtgctctgat aaaaaaggga ttagagtgca 120 ttgtgacacc gtgggatagt gattgtaact ttaaagatgg tacggttgtg cgtgtaattg 180 gttttagtga atggagcgcg tggggtttcc cacaattata ttt 223 <210> 585 <211> 223 <212> DNA <213> Artificial Sequence <400> 585 cttaaaccta acgaggtacg cgcctactat ggttatcctg aaacagacga gagtcagttt 60 tctagaatga caggctcacg tattaatgtt tcacgtgaaa caaacaatca aaataaggag 120 gctactactg atgaaaacgg agacgcgtag cattgagatt agagcacttg aggaaaatga 180 ggacatgatt gttgagggtt acgctgttac gttcaacagt gaa 223 <210> 586 <211> 223 <212> DNA <213> Artificial Sequence <400> 586 agagacataa agctagtcta actttgaacg aaaatcatgt gttaaaataa tataagaaag 60 acaagaaagg atgacacaaa catggcaaaa atcggtttta aatctgctca tattcatgtg 120 cccaataccg agggtacagg ctacacaacc tacaaccttg acaaaactaa aggcggtgca 180 attgaggcaa caatcagtgg actaggagcg gaggctacta cag 223 <210> 587 <211> 223 <212> DNA <213> Artificial Sequence <400> 587 ctagcgcttt tagtggtgag cgtcctgaaa tgccgtcaat tgagttcagt ctaaaatgta 60 acatgtcttt acccttgatg gtttctttct tttgagtgtc agggtcaatg tactcatatg 120 acaattcttt actcgctgtg tcttgtaaga ttgtaattgt atgagggctg acaatctgta 180 gcttagtaac ttgtgttccg ttgcgtctaa tgattgcaaa cgc 223 <210> 588 <211> 223 <212> DNA <213> Artificial Sequence <400> 588 cgttaagacg tattttgcca attattttca ataagcaagt gacaaaaggt gatgacaaag 60 taacgtttat gcgtcaattt aaccctgatg tgtctactga gatgagagac gcactaaaca 120 acgaacagga gaaagctgag tttattagat ggtgtgtaca ggagtatgct gaactattga 180 aacgcagaga ggacgttacc gcagacgagt ttgtgtggac gct 223 <210> 589 <211> 223 <212> DNA <213> Artificial Sequence <400> 589 tcagatgggt ttggggtgta gatggttgcc gtgtttccta gttcgatttt tatttttgtt 60 atagttataa ttaaagcatt tgaattaccc tgtatactaa aagcattagt tgcccctgcg 120 gttatacact caaatttata cgttgaaggt gtgtcacctt gttttattgt ttgccatgta 180 ctgagagcgt caaaattacc taccctaatt aacccattat tgt 223 <210> 590 <211> 223 <212> DNA <213> Artificial Sequence <400> 590 tcaggttggc aaagatatag tgatgttatg ggatacacta acacacctac agccacgcga 60 gtaggtagaa cggttcaaat agcaggtgcg tttaaaccca taaaccaact tagcgcaggt 120 caatatgaca ttaaccaacc tctaccagtt tgggctagac cattgaataa cgtaacactc 180 attcatcaag gttctggaat gaacaggcta ctactagaag tgc 223 <210> 591 <211> 223 <212> DNA <213> Artificial Sequence <400> 591 tcaatgatgg acgtggtgct gaaatggtta ttgacccaag tggtcaagcg gttatcccta 60 aaggtaagaa cgtaacgatg tggggacgaa aaggaaccca cgttttaaca gcagaagaaa 120 ctgcacacgt gttaggtcat aaacgtccta agtttgcata caaaaaaggt actggcttct 180 ttgacaaaat tacaggaggc gtaaaaaaca tctggaacgg tgc 223 <210> 592 <211> 223 <212> DNA <213> Artificial Sequence <400> 592 ctagcgcttt tagtggtgag cgtcctgaaa tgccgtcaat tgagttcagt ctaaaatgta 60 acatgtcttt acccttgatg gtttctttct tttgattgtc agggtcaatg tactcatatg 120 acaattcatt actcgctgtg tcttgtaaga ttgtaattgt atgagggctg acaatctgta 180 gcttagtaac ttgtgttccg ttgcgtctaa tgattgcaaa cgc 223 <210> 593 <211> 223 <212> DNA <213> Artificial Sequence <400> 593 ttctgttagt tgatgagtcg ttacacaaca ctcgcctgtt accgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggacttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat cctgtacgtt tgc 223 <210> 594 <211> 223 <212> DNA <213> Artificial Sequence <400> 594 ttaattctgt tgttgctaga ctaccagtcc accccttaga gatgaataca ctccctgata 60 cagtgtacgt tgtaccgcgc aaagcactgt agccatttga taggtatgca ggacgtattg 120 ttgacacggc tgttttagtt aatttagtgg ctcctgctgt tggtgtagcc gttactgcgt 180 caaagattcc ccaatactgt atactattgt cctgtgaacc gtt 223 <210> 595 <211> 223 <212> DNA <213> Artificial Sequence <400> 595 aagtctgaaa taatactcct tagacgctcc actgctgttg tctcattatc atagtttaaa 60 gtacgtgtct gattactaaa gtagtttgcg cccaatgtaa agcccgtgtc tctcatgaca 120 atgttcctgt agtattgaaa cgattgaggt gacgtggttt taatagcagg tacaacatta 180 ttaagtaagt caagtgcacc atcttcacaa cttatctcac gtg 223 <210> 596 <211> 223 <212> DNA <213> Artificial Sequence <400> 596 tgagaaaaat agactatggc aagcggtcaa cttctttact gacccactaa gtgaaaaagc 60 attatgtgag ttcatagggt catgcgtcta tgagaccaaa cctgaggctg ttcatgctca 120 aattgttgtc tcacgcggta cacgcaacgg aggaaatgga aagtctattc taatgaccaa 180 aatcataggc tcaccattgt ttggaaaaat gtacacagaa ctc 223 <210> 597 <211> 223 <212> DNA <213> Artificial Sequence <400> 597 tcgcactatc tactgtagta ccatacctac ttactagaat tgcaccatcc ttgcgcactt 60 ctagtagtag cctgttcatt ccagaacctt gatgactgag tgttacgtta ttcaatggtc 120 tagcccacac tggtagaggt tggttaatga catattgacc tgcgctaagt tggtttatgg 180 gtttaaacgc acctgctatt tgaaccgttc tacctactcg cgt 223 <210> 598 <211> 223 <212> DNA <213> Artificial Sequence <400> 598 ttcactgttg aacgtaacag cgtaaccctc aacaatcatg tcctcatttt cctcaagtgc 60 tctaatctca atgctacgcg tctccgtttt catcagtagt agcctcctta ttttgattgt 120 ttgtttctcg tgaaacatta atacgtgagc ctgtcattct agaaaactga ctctcgtctg 180 tttcaggata accatagtag gcgcgtacct cgttaggttt aag 223 <210> 599 <211> 223 <212> DNA <213> Artificial Sequence <400> 599 ctagcgcttt tagtggtgag cgtcctgaaa tgccgtcaat tgagttcagt ctaaaatgta 60 acatgtcttt acccttgatg gtttctttct tttgagtgtc agggtcaatg tactcatatg 120 acaattcatt actcgctgtg tcttgtaaga ttgtaattgt atgagggctg acaatctgta 180 gcttagtaac ttgtgttccg ttgcgtctaa tgattgcaaa cgc 223 <210> 600 <211> 223 <212> DNA <213> Artificial Sequence <400> 600 gcaccgttcc agatgttttt tacgcctcct gtaattttgt caaagaagcc agtacctttt 60 ttgtatgcaa acttaggacg tttatgacct aacacgtgtg cagtttcttc tgctgttaaa 120 acgtggggtc cttttcgtcc ccacatcgtt acgttcttac ctttagggat aaccgcttga 180 ccacttgggt caataaccat ttcagcacca cgtccatcat tga 223 <210> 601 <211> 223 <212> DNA <213> Artificial Sequence <400> 601 agagacataa agctagtcta actttgaacg aaaatcatgt gttaaaataa tataagaaag 60 acaagaaagg atgacacaaa catggcaaaa atcggattta aatctgctca tattcatgtg 120 cccaataccg agggtacagg ctacacaacc tacaaccttg acaaaactaa aggcggtgca 180 attgaggcaa caatcagtgg actaggagcg gaggctacta cag 223 <210> 602 <211> 222 <212> DNA <213> Artificial Sequence <400> 602 acgcatttgc tactgttacc gtagaaacgt tgttaggaat agctcctaat ttgaacatta 60 agcccgcctt tgtgtctgta gctactacgt caaatcggat ggcacccgct aacatttcac 120 cgtagacatt gtggtcttgc caacgtaccg tcatttcagt acgtttgaac aaagtaatag 180 cttgttctaa gtcaccaatg aataatagtt tatcatttgt gt 222 <210> 603 <211> 222 <212> DNA <213> Artificial Sequence <400> 603 taacattgtt gacaaagtca ccaactaaac caattacaat ttttagtagt ggactaataa 60 aattaaggaa gttcatgaac gcttccatga tttgtttacc atactgatta tagaactcgc 120 ttacctgatt gaaaatgcta ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 180 atggataaac cttttcaaac atgatggcgc ccatattcca ta 222 <210> 604 <211> 222 <212> DNA <213> Artificial Sequence <400> 604 ttaccggttg agccatctac aggaatatag ttcactgtat aggctactga tgttgtacca 60 tgagtgtact cccacgttgt acgtgtccat aggtctttac ctttatctag agttgggatg 120 gttctactcc ttcctgatgt aggttcatca acgcttgagg taatgattgc ccactctgtt 180 ttagttgatt tgacagaggc gccattttgt cccgttgttc tc 222 <210> 605 <211> 222 <212> DNA <213> Artificial Sequence <400> 605 tccagataat acgtgtccat aggtattgac cacctgttac atttggtggt gttgcttgcc 60 aacctgtgga tggtgctgtt gtacctgagg tacctacagc gtaagtaaca gcgatagatt 120 tcacaccctt accggttgag ccatctacag gaatatagtt cactgtatag gctactgatg 180 ttgtaccatc agtgtactcc cacgttgtac gtgtccatag gt 222 <210> 606 <211> 222 <212> DNA <213> Artificial Sequence <400> 606 aatgattcaa tgaaaattga aaaacaaatg cgctcaggtt taccacaagt aggggtaaga 60 ccgtatggac aaattcacgt acacagtacg gggacttcat catctacagc gcaaaacgag 120 gcagactatc atatgcgcag acccgtcaac agtgggttct tctcgcacgt agtaggtaac 180 gggcgagtaa ttcaaacagc acgcacaaac gcgggctttt at 222 <210> 607 <211> 222 <212> DNA <213> Artificial Sequence <400> 607 aacattgaaa cacaatctaa aaaaggtaac ccaatgagac gcctgaaact ccgtgagaca 60 cgcacaggta gggaggctgt ttcttactta atgacttgga aacctgattt tacacgttgg 120 gaggacattg agccactatc agtggtgagg gtagacattg agttaaaaga tgggttctat 180 aatttaggta agcctgaaat tgcaggcaag gttgatgaag tt 222 <210> 608 <211> 222 <212> DNA <213> Artificial Sequence <400> 608 aacttcatca accttgcctg caatttcagg cttacctaaa ttatagaacc catcttttaa 60 ctcaatgtct accctcacca ctgatagtgg ctcactgtcc tcccaacgtg taaaatcagg 120 tttccaattc attaagtaag aaacagcctc cctacctgtg cgtgtctcac ggagtttcag 180 gcgtctcatt gggttacctt ttttagattg tgtttcaatg tt 222 <210> 609 <211> 222 <212> DNA <213> Artificial Sequence <400> 609 ccagataata cgtgtccata ggtattgacc acctgttaca tttggtggtg ttgcttgcca 60 acctgtggat ggtgctgttg tacctgaggt acctacagcg taagtaacag cgatagattt 120 cacaccagta ccggttgagc catctacagg aatatagttc actgtatagg ctactgatgt 180 tgtaccatca gtgtactccc acgttgtacg tgtccatagg ta 222 <210> 610 <211> 222 <212> DNA <213> Artificial Sequence <400> 610 acacaaatga taaactatta ttcattggtg acttagaaca agctattact ttgttcaaac 60 gtactgaaat gacggtacgt tggcaagacc acaaggtcta cggtgaaatg ttagcgggtg 120 ccatccgttt tgacgtagta gctacagaca caaaggcggg cttaatgttc aaattaggag 180 ctattcctaa caacgtttct acggtaacag tagcaaatgc gt 222 <210> 611 <211> 222 <212> DNA <213> Artificial Sequence <400> 611 tatggaatat gggcgccatc atgtttgaaa aggtttatcc attattaaaa cccatactag 60 acacgatttt tagtgcgttc ggtagcattt tcaaacaggt aagcgagttc tataatcagt 120 atggtaatca aatcatggaa gcgttcatga acttccttaa ttttattagt ccactactaa 180 aaattgtaat tggtttagtt ggtgactttg tcaacaatgt ta 222 <210> 612 <211> 222 <212> DNA <213> Artificial Sequence <400> 612 ataaaagccc gcgtttgtgc gtgctgtttg aattactcgc ccgttaccta ctacgtgcga 60 gaagaaccca ctgttgacgg gtctgcgcat atgagagtct gcctcgtttt gcgctgtaga 120 tgatgaattc cccgtactgt gtacgtgaat ttgtccatac ggtcttaccc ctacttgtgg 180 taaacctgag cgcatttgtt tttcaatttt cattgaatca tt 222 <210> 613 <211> 222 <212> DNA <213> Artificial Sequence <400> 613 ctcagtggcg cgctttggtc aggatggtat tagtgtgact ggtactcaat cagagtatgt 60 acaaacaact agttctgtag aacctacctc aggagggagt acaacacgtc caacacctca 120 aattggtatg tggttgtggg taaggagtag aaatacgctt tcaaatggta cgtatacaaa 180 gtgggtagta actagctcat acacgggtag agactcaatt tt 222 <210> 614 <211> 222 <212> DNA <213> Artificial Sequence <400> 614 ccagataata cgtgtccata ggtattgacc acctgttaca tttggtggtg ttgcttgcca 60 acctgtggat ggtgctgttg tacctgaggt acctccagcg taagtaacag cgatagattt 120 cacaccatta ccggttgagc catctacagg aatatagttc actgtatagg ctactgatgt 180 tgtaccatca gtgtactccc acgttgtacg tgtccatagg ta 222 <210> 615 <211> 222 <212> DNA <213> Artificial Sequence <400> 615 tacctatgga cacgtacaac gtgggagtac actgatggta caacatcagt agcctataca 60 gtgaactata ttcctgtaga tggctcaacc ggtactggtg tgaaatctat cgctgttact 120 tacgctggag gtacctcagg tacaacagca ccatccacag gttggcaagc aacaccacca 180 aatgtaacag gtggtcaata cctatggaca cgtattatct gg 222 <210> 616 <211> 222 <212> DNA <213> Artificial Sequence <400> 616 tatggaatat gggcgccatc atgtttgaaa aggtttatcc attattaaaa cccatactag 60 acacgatttt tagtgcgttc ggtagcattt tcaatcaggt aagcgagttc tataatcagt 120 atggtaatca aatcatggaa gcgttcatga acttccttaa ttttattagt ccactactaa 180 aaattgtaat tggtttagtt ggtgactttg tcaacaatgt ta 222 <210> 617 <211> 222 <212> DNA <213> Artificial Sequence <400> 617 ataaaagccc gcgtttgtgc gtgctgtttg aattactcgc ccgttaccta ctacgtgcga 60 gaagaaccca ctgttgacgg gtctgcgcat atgagagtct gcctcgtttt gcgctgtaga 120 tgatgaagtc cccgtactgt gtacgtgaat ttgtccatac ggtcttaccc ctacttgtgg 180 taaacctgag cgcatttgtt tttcaatttt cattgaatca tt 222 <210> 618 <211> 222 <212> DNA <213> Artificial Sequence <400> 618 aacttcatca accttgcctg caatttcagg cttacctaaa ttatagaacc catcttttaa 60 ctcaatgtct accctcacca ctgatagtgg ctcactgtcc tcccaacgtg taaaatcagg 120 tttccaagtc attaagtaag aaacagcctc cctacctgtg cgtgtctcac ggagtttcag 180 gcgtctcatt gggttacctt ttttagattg tgtttcaatg tt 222 <210> 619 <211> 222 <212> DNA <213> Artificial Sequence <400> 619 acgcatttgc tactgttacc gtagaaacgt tgttaggaat agctcctaat ttgaacatta 60 agcccgcctt tgtgtctgta gctactacgt caaatcggat ggcacccgct aacatttcac 120 cgtagacctt gtggtcttgc caacgtaccg tcatttcagt acgtttgaac aaagtaatag 180 cttgttctaa gtcaccaatg aataatagtt tatcatttgt gt 222 <210> 620 <211> 221 <212> DNA <213> Artificial Sequence <400> 620 atggtatcac taatagatac accattggtt atactgtcat ataccttttg ttctatctca 60 ttatcagcta acaggtagta gtacacaggg tcactggtag atgtgtgccg tgctatccgt 120 cccttcagtt gttggtacgt aatactagaa aggggtagct cgtagaatac cattatgtgg 180 gatgtagcta agaagtttac ccctgtactt cctgccttga a 221 <210> 621 <211> 221 <212> DNA <213> Artificial Sequence <400> 621 catcccattt agaacacctc tgagcgtctc tatacgcctt tatttgaaca tccaaagcgt 60 cctcaccctc ttttagtatt cctctgagat gttttatctt atcctctagc tcgtcatagg 120 gtcgtaatat ttctttttta acccgcttgc gttcgttgtc tatgttgcta aactctttgc 180 gagcctgtgc gaggagtttt ttatattcct ttatgttgtc c 221 <210> 622 <211> 221 <212> DNA <213> Artificial Sequence <400> 622 ttgttggtac gtaatactag aaaggggtag ctcgtagaat accattatgt gggatgtagc 60 taagaagttt acccctgtac ttcctgcctt gaagtgtact agaataatcg cgtcctcatg 120 ttgttcccat gtctctaagt ccttaataga gccattatat attgagatag gtctatcacc 180 tttagacaat tcctctacta atctattaca cgtttcttta t 221 <210> 623 <211> 221 <212> DNA <213> Artificial Sequence <400> 623 gcttttgtgc ctcaatagct ttctcagtta aggagattga acgttttaga ccctcctgtt 60 tagcctcaag tgcgcccgct gagtcccctg cgtcttttag tgcttttact tgttgttgag 120 tctcacggtc gttctgtttc atttctttag aaagttgtgt tagtccactc ttagcgtcaa 180 tgtattcctt ggaggttttt tctagttgac tagttaaacc a 221 <210> 624 <211> 221 <212> DNA <213> Artificial Sequence <400> 624 tcgttctgtt tcatttcttt agaaagttgt gttagtccac tcttagcgtc aatgtattcc 60 ttggaggttt tttctagttg actagttaaa ccagtgtatt ttgctgtggc gttattgatt 120 tgagtgctta gagactgaac ctgtttagac tcagccccgt atttctttat agcgtcctct 180 ctacgtttgt ttaaaacctc aatgcgtttc tcttgaattt t 221 <210> 625 <211> 221 <212> DNA <213> Artificial Sequence <400> 625 agcacggacc caagtaagta cacgtggatg agaacaacgg gacaaaatgg cgcctctgtc 60 aaatcaacta aaacagagtg ggcaatcaat accacaagcg ttgatgaacc tacatcagga 120 tggagtacaa ccatcccaac tctagaaaaa ggtaaatacc tatggacacg tacaacgtgg 180 gagtacactg atggtacaac atcagtagcc tatacagtga a 221 <210> 626 <211> 221 <212> DNA <213> Artificial Sequence <400> 626 tacttttgtt ccaatgcctc tacactatca gaggcaccgt caaacgcttt gatgtttgcc 60 ttcatggagc tttcagcttg tttgaattgt tttgttagtt tgtcaagtgt attacctagt 120 tcagcgggtc cgtcaatacc taaaccaaac ttcatatttc ctactggttt tccgctttgc 180 accatgtgtt aatcagctcc ttttttctct agcttttcaa g 221 <210> 627 <211> 221 <212> DNA <213> Artificial Sequence <400> 627 catcccattt agaacacctc tgagcgtctc tatacgcctt tatttgaaca tccaaagcgt 60 cctcaccctc ttttagtatt cctctgagat gttgtatctt atcctctagc tcgtcatagg 120 gtcgtaaaat ttctttttta acccgcttgc gttcgttgtc tatgttgcta aactctttgc 180 gagcctgtgc gaggagtttt ttatattcct ttatgttgtc c 221 <210> 628 <211> 221 <212> DNA <213> Artificial Sequence <400> 628 taactataac aaaaataaaa atcgaactag gaaacacggc aaccatctac accccaaacc 60 catctgaaga tttcgcgaac gcatatccgc tatatatggg tcaatatagt aactatactc 120 aagaaccgag cacggaccca agtaagtaca cgtggatgag aacaacggga caaaatggcg 180 cctctgtcaa atcaactaaa acagagtggg caatcaatac c 221 <210> 629 <211> 221 <212> DNA <213> Artificial Sequence <400> 629 catcccattt agaacacctc tgagcgtctc tatacgcctt tatttgaaca tccaaagcgt 60 cctcaccctc ttttagtatt cctctgagat gttgtatctt atcctctagc tcgtcatagg 120 gtcgtaatat ttctttttta acccgcttgc gttcgttgtc tatgttgcta aactctttgc 180 gagcctgtgc gaggagtttt ttatattcct ttatgttgtc c 221 <210> 630 <211> 220 <212> DNA <213> Artificial Sequence <400> 630 gaacgcctct gtactacgtt cagcctcctc atcatgagga atgtaggcgt gacagtctgt 60 gttgctctgt aacatggtaa catggtccct aagtccctcg tagaagtcag ccataattaa 120 ttgcccaatc acacatgtta gaaattgaaa acgtgggtca tataacccat taaactctgc 180 acctgtggca ccaaacaatg tattaatagg caattttacc 220 <210> 631 <211> 220 <212> DNA <213> Artificial Sequence <400> 631 tagggacacc accaattttg tttaggtcct cgttaaatcg ctctttaacc tcatcttttt 60 tagtccattc ttttgtctta ctattgtagt cctctttgta caatgttaat gtgtacagtt 120 ttgaatattc ctcaggacac acactaatca ctaaactttt gtcctcgtcc tcaactgcta 180 caactgttaa tttttcaggt tctttactca ttaaaatctc 220 <210> 632 <211> 220 <212> DNA <213> Artificial Sequence <400> 632 acctgaaaac attcatgtaa ctataccaga gattagagaa atgtttttag accatgagtt 60 tgacctaaat aaaaaaggta agcccgtagc taaaggaacg tatactgacc ctaatactgg 120 ttatgttctg gagtttggcg cgggaggtgt ccacggagct gttgaacagc ttattcacat 180 tggacgcttt ctcatgcgtg actacggtag tttgtaccct 220 <210> 633 <211> 220 <212> DNA <213> Artificial Sequence <400> 633 tgtactgaga gcggcaaaat tacctaccct aattaaccca ttattgttgc ggaaggcgtc 60 tattgtgacg gaatatttca ctcctgctgg cacgtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg 220 <210> 634 <211> 220 <212> DNA <213> Artificial Sequence <400> 634 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg cacgtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc attaatagtg 220 <210> 635 <211> 220 <212> DNA <213> Artificial Sequence <400> 635 gttgaggatg agtttgttat tgttaagatt gctaaaaatg atttaggtaa ccttgatgtt 60 gcgtatgagc tagtataaca acgttttaca cataaatggt ataataacac tatatgaaat 120 aagagagtga gattttaatg agtaaagaac ctgaaaaatt aacagttgta gcagttgagg 180 acgaggacaa aagtttagtg attagtgtgt gtcctgagga 220 <210> 636 <211> 220 <212> DNA <213> Artificial Sequence <400> 636 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gtgaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactaatg cttttagtat acagggtaat 220 <210> 637 <211> 220 <212> DNA <213> Artificial Sequence <400> 637 tcgttcattg taatctctgt ttcatctgta tatttagcct ctagacgtgt atctaagagt 60 tctttcacta ggtgcttatt ctcctcaggt tcgttacgag aaagaagatc aaatttcaga 120 tacacatgag ggtacaaact accgtagtca cgcatgagaa agcgtccaat gtgaataagc 180 tgttcaacag ctccgtggac acctcccgcg ccaaactcca 220 <210> 638 <211> 220 <212> DNA <213> Artificial Sequence <400> 638 ggtaaaattg cctattaata cattgtttgg tgccacaggt gcagagttta atgggttata 60 tgacccacgt tttcaatttc taacatgtgt gagtgggcaa ttaattatgg ctgacttcta 120 cgagggactt agggaccatg ttaccatgtt acagagcaac acagactgtc acgcctacat 180 tcctcatgat gaggaggctg aacgtattac agacgcgttc 220 <210> 639 <211> 220 <212> DNA <213> Artificial Sequence <400> 639 agtttgacat cacagggcgt gaagtattta ttggtataga cctagcacga gtaaatgact 60 tgaccgctgt tacgtgggtt attcctatcc ctgaaaaaga attgtatatt gttgactctc 120 acgcgtgggt agcaacaacg ggtggtggta ttgttcagaa agaggctaac gatagaacac 180 cctatagaca atattccaaa caggggtatt gtgaaatttc 220 <210> 640 <211> 220 <212> DNA <213> Artificial Sequence <400> 640 cccaacgttt accactaaac aaatctttag cacaaatgac aaaatcttgc tcaaatacct 60 cactatcata aattactaaa tattgtttcc cgcttggttt attgggacgc ggtggaactt 120 catcaccctt gcctgcaatt tcaggcttac ctaaattata gaacccatct tttaactcaa 180 tgtctaccct caccactgat agtggctcaa tgtcctccca 220 <210> 641 <211> 219 <212> DNA <213> Artificial Sequence <400> 641 acaaatacca gacgactatt taggaggtaa taagcaatga gtaatatgtt tgaggtaggt 60 cacagagtag tatgtgtaga cactttatgt gtagaagata tattggaaaa aggtaaacga 120 tataccagtg ttggagtagg cagccttttc gtgcaggttg atggtattga tgaatggttc 180 tactatgacc gttttgaacg tgactatgtt aatgaggga 219 <210> 642 <211> 219 <212> DNA <213> Artificial Sequence <400> 642 acccaactgc gccatttctt taactttaac taactgctct tgtgattcat caaaatgtaa 60 tacccctgtg aactctataa tgtcatctgt ttcatagttg attatctcat ggtcatctga 120 cattttattg agtcctgctc catctgtgga cgcaattcct atagggttaa attccctatc 180 agtaaaataa aattctattt taaaaacccc ccttacact 219 <210> 643 <211> 219 <212> DNA <213> Artificial Sequence <400> 643 tgagtcctgc tccatctgtg gacgcaattc ctatagggtt aaattcccta tcagtaaaat 60 aaaattctat tttaaaaacc ccccttacac tggtttcttt attaattata ccataaaaaa 120 gccactcttt ggcgagtggc tagatgttat tacaagtagg ttcgttggtt cttcacagtt 180 acttctaaag tgtctgtagc ccaatctgag ttaatgaac 219 <210> 644 <211> 219 <212> DNA <213> Artificial Sequence <400> 644 ttaccctgta tactaaaagc attagttgcc cctgcggtta taccctcaaa tttatacgtt 60 gaaggtgtgt caccttgttt tattgtttgc catgtactga gagcgtcaaa attacctacc 120 ctaattaccc cattattgtt gctgaatgcg tctattgtga cggaatattt aactcctgct 180 ggcaagtagt tggttaataa gtcattgcta taatagact 219 <210> 645 <211> 219 <212> DNA <213> Artificial Sequence <400> 645 gagtagccat ctagatgttt taacaacgga agctttgttt gctacaggtg cattgtaggt 60 aaatgggttt tttgtaactg gtttaattcc ggtgtttgat tggatatgct caaagttcca 120 agtgaacttc ttacccgttt ggtcacgtgt cattgtacag cggaaccaag atgatttgta 180 cttagttacg tctgtcttga tagattttag taacttgtt 219 <210> 646 <211> 219 <212> DNA <213> Artificial Sequence <400> 646 ggaatacatt gacgctaaga gtggactaac acaactttct aaagaaatga aacagaacga 60 acgtgagact caacaacaag taaaagcact aaaagacgca ggggactcag cgggcgcact 120 tgaggctcaa caggagggtc taaaacgttc aatctcctta actgagaaag ctattgaggc 180 acaaaagcgc gctattgaaa tgagttctca ggagttcgg 219 <210> 647 <211> 219 <212> DNA <213> Artificial Sequence <400> 647 agttttttgt aaatggtgag ggtacaatca gtatatcagc taaagttgtc aaaggcaagg 60 atgacattac tgataatttt acttcgtttg tatggcgtag atatgacgcc tcaaacgtat 120 tagacacctc atggacagca acaggaaaaa caatcacagt aaatgcagga caatcaaatg 180 tatatacata ttattgttct gtagattatt agaggaggt 219 <210> 648 <211> 219 <212> DNA <213> Artificial Sequence <400> 648 aacaggttgg acgtttgaca agactgtata cgttgatagt gatggtaatg aacatgacgc 60 acagaaagta aaccgtgtgt ttgctgtgaa atcgggtgat aaagctgtta acttattcaa 120 agtaaaaacc ggtaaacttg aaccagttga aaatgaggac ggagaacttg aaacagaaga 180 agtaacctat attaaaggtg atgactcata tgtaacagg 219 <210> 649 <211> 219 <212> DNA <213> Artificial Sequence <400> 649 ccgaactcct gagaactcat ttcaatagcg cgcttttgtg cctcaatagc tttctcagtt 60 aaggagattg aacgttttag accctcctgt ttagcctcaa gtgcgcccgc tgagtcccct 120 gcgtcttgta gtgcttttac ttgttgttga gtctcacgtt cgttctgttt catttcttta 180 gaaagttgtg ttagtccact cttagcgtca atgtattcc 219 <210> 650 <211> 219 <212> DNA <213> Artificial Sequence <400> 650 ttgggtattg gagtgtgaac ctctcttttc catcactact ccatgcgtaa gctgtgtgta 60 aaaatggatt ttgaccatcc tgtacgtttg caatactcaa tggctttgac tctaatgcca 120 tgtttttgac ctcctctaat aatctacaga acaataatat gtatatacat ttgattgtcc 180 tgcatttact gtgattgttt ttcctgttgc ggtccatga 219 <210> 651 <211> 219 <212> DNA <213> Artificial Sequence <400> 651 ttaggtaaca gaccgtatga cttgtaacta gtcttggaac ctgcacgaat gtgtaggact 60 tccttagatt tcattgtcca tgttacctta tccactacct cccttgtggc tactgagtct 120 ttatactgga gtagccatct agatgtttta acaacggaag ctttgtttgc tacaggtgca 180 ttgtaggtaa atgggttttt tgtaactggt ttaattccg 219 <210> 652 <211> 219 <212> DNA <213> Artificial Sequence <400> 652 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct agagacaata ttccaaacag gggtattgtg 120 aaatttcttc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtattt 219 <210> 653 <211> 219 <212> DNA <213> Artificial Sequence <400> 653 actattaatg gttggacagg aaatggtgcg actatagaat attcaaacgg gaacatgcga 60 gtgttgttta acgactcatc aactaacaga atagtctatt atagcaatga cttattaacc 120 aactactagc cagcaggagt taaatattcc gtcacaatag acgcattcag caacaataat 180 gggttaatta gggtaggtaa ttttgacgct ctcagtaca 219 <210> 654 <211> 219 <212> DNA <213> Artificial Sequence <400> 654 aaaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct agagacaata ttccaaacag gggtattgtg 120 aaatttcgtc ccgtcctgac ggtcagtgtg attgggagga tatgttaaat tgggttttgg 180 cgtttattga gacaaacaat ttagacgtac aaggtattt 219 <210> 655 <211> 219 <212> DNA <213> Artificial Sequence <400> 655 ccgaactcct gagaactcat ttcaatagcg cgcttttgtg cctcaatagc tttctcagtt 60 aaggagattg aacgttttag accctcctgt tgagcctcaa gtgcgcccgc tgagtcccct 120 gcgtcttgta gtgcttttac ttgttgttga gtctcacgtt cgttctgttt catttcttta 180 gaaagttgtg ttagtccact cttagcgtca atgtattcc 219 <210> 656 <211> 219 <212> DNA <213> Artificial Sequence <400> 656 cctgttacat atgagtcatc acctttaata taggttactt cttctgtttc aagttctccg 60 tcctcatttt caactggttc aagtttaccg gattttactt tgaataagtt aacagcttta 120 tcacccgatt tcacagcaaa cacacggttt actttctgtg cgtcatgttc attaccatca 180 ctatcaacgt atacagtctt gtcaaacgtc caacctgtt 219 <210> 657 <211> 218 <212> DNA <213> Artificial Sequence <400> 657 tttaattaaa gttgaaacaa ccatgttgga ccctgcgtca ggttggcaaa gatatagtga 60 tgttatggga tacactaaca cacctacagc cacgcgagta ggtagaacgg ttcaaatagc 120 aggtgcgatt aaacccataa accaacttag cgcaggtcaa tatgtcatta accaacctct 180 accagtttgg gctagaccat tgaataacgt aacactca 218 <210> 658 <211> 218 <212> DNA <213> Artificial Sequence <400> 658 aatgatattt ttgaggcgtg tgagattgct gaacacttac agggtgtaga acgcgttata 60 gaagttgtga ggttggtgct atgataaaaa agggtttaga gtgcattgtg acaccgtggg 120 atagtgagtg taactttaaa gatggtacgg ttgtgcgtgt aattggtttt agtgaatgga 180 gcgcgtgggg tttcccacaa ttatatttat gtacagat 218 <210> 659 <211> 218 <212> DNA <213> Artificial Sequence <400> 659 atctgtacat aaatataatt gtgggaaacc ccacgcgctc cattcactaa aaccaattac 60 acgcacaacc gaaccatctt taaatttaca atcactatcc cacggtttca caaagcaatc 120 tcaacccatt tttatcatag caccaaccac acaacttcta taacgcgttc tacaccctgt 180 aagtgttcag caatctcaca cgcctcaaaa atatcatt 218 <210> 660 <211> 218 <212> DNA <213> Artificial Sequence <400> 660 ttggtattta gttgctttgg cgcgtacttt tactttacta cctacaggga aatcacgtgt 60 gtctgtgatt tttggtttag acggttgtgg gtttggttta ggtttgttgt cagtattgga 120 actatttcca ccaaacccat ttttaatgtc tttagcaaac tgctctttac taattcccca 180 tttacgcaag tatggatagg ggtcaatatg gtcagaac 218 <210> 661 <211> 218 <212> DNA <213> Artificial Sequence <400> 661 tatagtccct catgtcctct tttaccattt tacgcgttat tctacttcta tcatctgtgt 60 tgtatctgtt tgctagaaga ataccgtccg agaagagttt caattcaaca aggtcaccct 120 cattacccgt gtgctcaaat agtccactat taaaggctaa atcaataaca ggtgttttac 180 tacgtactag ttcctcacgc atttccttag cctcatca 218 <210> 662 <211> 218 <212> DNA <213> Artificial Sequence <400> 662 ttctgttagt tgaggagtcg taaaacaaca ctcgcatgtt cccctgtgaa gatactatag 60 tcgcaccctt ccctctccaa ccattaatag aggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat cctgtacg 218 <210> 663 <211> 218 <212> DNA <213> Artificial Sequence <400> 663 tctttgacgc agtaacggct acaccaacag caggagccac taaattaact aaaacagcag 60 tgtcaacaat acgtcctgca tacctatcaa atggctacag tgctttgcgc ggtacaacgt 120 ccactgtatc agggagtgta gtcatctcta aggggtggac tggtagtcta gcaacaacag 180 aattaattgt gcgtgttccc tcctctgata gtacgcgc 218 <210> 664 <211> 218 <212> DNA <213> Artificial Sequence <400> 664 tatagtccct catgtcctct tttaccattt tacgcgttat tctacttcta tcatctgtgt 60 tgtatctgtt tgctagaaga ataccgtccg tgaagagttt caattcaaca aggtcaccct 120 cattaccagt gtgctcaaat agtccactat taaaggctaa atcaataaca ggtgttttac 180 tacgtactag ttcctcacgc atttccttag cctcatca 218 <210> 665 <211> 218 <212> DNA <213> Artificial Sequence <400> 665 ttttgtcctc gtcctcaact gctacaactg ttaatttttc aggttcttta ctcattaaaa 60 tctccctctc ttatttcata tagtgttatt ataccattta tgtgtaaaac gttgttatac 120 tagctcagac gcaacatcaa ggttacctaa atcattttta gcaatcttaa caataacaaa 180 ctcatcctca acttcatcct gttccccatc cacgcgta 218 <210> 666 <211> 218 <212> DNA <213> Artificial Sequence <400> 666 ttacctgttt gaaaatgcta ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 60 atggataaac cttttcaaac atgatggcgc acatattcca taataactcc gtgatggttt 120 taatataatc gccaaccggt tccagtattg gttgtaactt accaaacacc tcacctaaat 180 attgccctac ttttggtaag atgtcttttg taaagttt 218 <210> 667 <211> 218 <212> DNA <213> Artificial Sequence <400> 667 atctgtacat aaatataatt gtgggaaacc ccacgcgctc cattcactaa aaccaattac 60 acgcacaacc gtaccatctt taaagttaca ctcactatcc cacggtgtca caatgcactc 120 taaacccatt tttatcatag caccaacctc acaacttcta taacgcgttc tacaccctgt 180 aagtgttcag caatctcaca cgcctcaaaa atatcatt 218 <210> 668 <211> 218 <212> DNA <213> Artificial Sequence <400> 668 tgatgaggct aaggaaatgc gtgaggaact agtacgtagt aaaacacctg ttattgattt 60 agcctttaat agtggactat ttgagcacac tggtaatgag ggtgaccttg ttgaattgaa 120 actcttctcg gacggtattc ttctagcaaa cagatacaac acagatgata gaagtagaat 180 aacgcgtaaa atggtaaaag aggacatgag ggactata 218 <210> 669 <211> 218 <212> DNA <213> Artificial Sequence <400> 669 ttacctgttt gaaaatgcta ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 60 atggataaac cttttcaaac atgatggcgc acatattcca taataactcc gtgatggttt 120 taatatactc gccaaccggt tccagtattg gttgtaactt accaaacacc tcacctaaat 180 attgccctac ttttggtaag atgtcttttg taaagttt 218 <210> 670 <211> 218 <212> DNA <213> Artificial Sequence <400> 670 atcatgtaat gttagttcca ttctattcat cctcctcaaa taagtcatat gttttattct 60 ctggtaattt tggcaattta tacgtgctaa tgtgtcccgt gtctatcaag tgaaaaatag 120 tttctatctc ctgtagttca gcctttagta tgagacctat gacgccttgt tctctcacgc 180 gttgtaaaaa acgtctttgt aggcttgttg gttggtac 218 <210> 671 <211> 217 <212> DNA <213> Artificial Sequence <400> 671 acgagaacat ttagctatgg tgggagaggg taataaacct gaaatggtta ttccactaga 60 caaagccaaa cgctcacgcg ctatgtatct actagctgag gcacaaaagc ggttaggtgt 120 atcacaatca accgtggtag ctggtcaggg ttctaatgat gagctaattg ctcaattgat 180 tgtacagcaa caacaaacaa acgcactgtt acaagca 217 <210> 672 <211> 217 <212> DNA <213> Artificial Sequence <400> 672 tgctttttca cttagtgggt cagtaaagaa gttgaccgct tgccatagtc tatttttctc 60 aatctctggt agcgtcacag gtgtctcttg tacatgaatg ggtaaaatgg tgtcttgcgt 120 tctatagtcc catggttcaa acggacgtag ttctaatgta cgcatgttta gcgcaccgtt 180 ttgaaaatac gcacattcac caaggtatct gtactta 217 <210> 673 <211> 217 <212> DNA <213> Artificial Sequence <400> 673 tgtcctcatt ttcctcaagt gctctaatct caatgctacg cgtctccgtt ttcatcatta 60 gtagcctcct tattttgatt gtttgtttca cgtgaaacat taatacgtga gcctgtcatt 120 ctagaaatct gactctcgtc tgtttcagga taaccatagt aggcgcgtac ctcgttaggt 180 ttaagatact caatgccttt ggctgtaccc tcaaaca 217 <210> 674 <211> 217 <212> DNA <213> Artificial Sequence <400> 674 atagttagca tataatgtga gtgttcggtc atcaacacct tgctcacgca tgtcgttttc 60 taaatcaatt aaaatacggt ctgtgttttc aacttctact aataactcat agttattcat 120 cttcgttgtc ctcctcatct aacatactaa gttcttcgcg taagaacttg acaacccctt 180 ctaatagctc aattgtttcc tctttgttta ggttctc 217 <210> 675 <211> 217 <212> DNA <213> Artificial Sequence <400> 675 gcacgtgtgt atttagatac gctaattaaa tttgaggagg aaaaataatg aacattcata 60 ctgatttact tattttggct gtagacatga acacaggtaa ggcaacggga gcaatagagg 120 gggaaggaga gaacctaaac aaagaggaaa caattgagct attagaaggg gttgtcaagt 180 tcttacgcga agaacttagt atgttagatg aggagga 217 <210> 676 <211> 217 <212> DNA <213> Artificial Sequence <400> 676 atggatagtt ttgacgaggc ggatgacgag gaaaactggt ttaaatctaa ccctcttttt 60 gaaaaacctg acgttcgcac acatatgtta gaacacaatc gggctaaaaa gacagaggga 120 gaggctaaag gtaatctcac caacttccta actaaggagc ttaatttttg ggttgcggac 180 caagcaacgt catacatttc tgtagacgag tgggaaa 217 <210> 677 <211> 217 <212> DNA <213> Artificial Sequence <400> 677 ggagttagaa actatttttc acttgataga cacgggacac attagcacgt ataaattgcc 60 aaaattacca gagattaaaa catatgactg atttgaggag gatgaataga atggaactaa 120 cattacatga ttttgagtat aacgaggata tgattgacgt atatgattta gatgatacgt 180 tagtgtttta tactagtgag aaaataggga gtagtac 217 <210> 678 <211> 217 <212> DNA <213> Artificial Sequence <400> 678 cctatgattt tggtcattag aatagacttt ccatttcctc cgttgcgtgt accgcgtgag 60 acaacaattt gagcatgaac agcctcaggt ttgttctcat agacgcatga ccctatgaac 120 tcacatactg ctttttcact tagtgggtca gtaaagaagt tgaccgcttg ccatagtcta 180 tttttctcaa tctctggtag cgtcacaggt gtctctt 217 <210> 679 <211> 217 <212> DNA <213> Artificial Sequence <400> 679 tataaactct ttaacacgaa gaaaactcct attctaggtt gtgacctgta ccatgaacac 60 aaagggtttt cactgaaaga acatgagggg ttcatggggt tagaagtcaa agagacggat 120 gttgactttg aacaaggcgg taaactaaca gatgaggaac tacgcaaaga ggttgcttat 180 tgttggaaag acgtagacgc cactgagcta cgcttct 217 <210> 680 <211> 217 <212> DNA <213> Artificial Sequence <400> 680 ttcgtcaaga taaccgtatt cagatacctc ttgagttgcc tgactgtaaa tagcgtaagt 60 attacaataa atgactagca tgccagcgta tagttttgaa attggtagct gtttaagttg 120 tggaacaagg tcctcgtaaa tcaaccaccc ttccttagta attccctcag gaatatcgtc 180 taatgaaagt tgttcataat tatataactc ttgttct 217 <210> 681 <211> 217 <212> DNA <213> Artificial Sequence <400> 681 gtgacagtct atttactggt tataactctg ctagttatga taataatgtg ctccgtggtt 60 atttacaagg taaagacgcg tttcagttgt cacaggctgt tattaagtca gatgatagag 120 gacttatgta taaactcttt aacacgaaga aaactcctat tctaggttgt gacctgtacc 180 atgaacacaa agggttttca ctgaaagaac atgaggg 217 <210> 682 <211> 217 <212> DNA <213> Artificial Sequence <400> 682 caaccgtggt agctggtcag ggttctaatg atgagctaat tgctcaattg attgtacagc 60 aacaacaaac aaacgcactg ttacaagcag tactagaaaa ggacacggac gtctacttag 120 acaaacgtaa agttactgcg gaactaaacc ctgctttaac taaagataag caacgcggac 180 aaatggtatc taacagacgt caagggcgtt tagcata 217 <210> 683 <211> 217 <212> DNA <213> Artificial Sequence <400> 683 ttgaacacgg ggtactcttt gccaaacctc caatttacac tattaaactc acctgtgtaa 60 attaaaacat ctccgacttt tagttcatta actttaacca ttgttttcct ccttaatatt 120 caacactcac aatgtagtac ggttgtatta ctacattcac gggcacagag cttagtagca 180 taatctgaaa aacctctcct gtttgcatac gttcaat 217 <210> 684 <211> 217 <212> DNA <213> Artificial Sequence <400> 684 agcacttgta aacaactttt tacatccctt tttataaaat aatatggtat aatatgtgta 60 tacttattat acattgtttt tctccctaat aagcactaca cgctgattcc tcccaacgtg 120 tagtgctttt tattattttg acgagttaag ttcgtcaatt gtgtcattgt atgcagtagc 180 taggttattc atgaggtcac caatttttcc aattatt 217 <210> 685 <211> 217 <212> DNA <213> Artificial Sequence <400> 685 ttggaaacgt gaaaaaggta gatgattata tgacacctgt tattaatgaa agcaatgaga 60 cccgtaccat taccatctgc atggtcaacg gacgctctta cacatataag ggttccccag 120 agtttgtgat tgaacgtatg caaacaggag aggtttttca gattatgcta ctaagctctg 180 tgcccgtgaa tgtagtaata caaccgtact acattgt 217 <210> 686 <211> 217 <212> DNA <213> Artificial Sequence <400> 686 cataaaccaa cttagcgcag gtcaatatgt cattaaccaa cctctaccag tttgggctag 60 accattgaat aacgtaacac tcattcatca aggttctgga atgaacaggc tactactaga 120 agtgcgctag gatggtgcaa ttctagtaag taggtatggt actacagtag atagtgcgat 180 tccgtcaggc gcatggataa acatctcttg cgtatat 217 <210> 687 <211> 217 <212> DNA <213> Artificial Sequence <400> 687 gtactactcc ctattttctc actagtataa aacactaacg tatcatctaa atcatatacg 60 tcaatcatat cctcgttata ctcaaaatct tgtaatgtta gttccattct attcatcctc 120 ctcaaataag tcatatgttt taatctctgg taattttggc aatttatacg tgctaatgtg 180 tcccgtgtct atcaagtgaa aaatagtttc taactcc 217 <210> 688 <211> 217 <212> DNA <213> Artificial Sequence <400> 688 cataaaccaa cttagcgcag gtcaatatgt cattaaccaa cctctaccag tttgggctag 60 accattgaat aacgtaacac tcattcatct aggttctgga atgaacaggc tactactaga 120 agtgcgcaag gatggtgcaa ttctagtaag taggtatggt actacagtag atagtgcgat 180 tccgtcaggc gcatggataa acatctcttg cgtatat 217 <210> 689 <211> 217 <212> DNA <213> Artificial Sequence <400> 689 ggagttagaa actatttttc acttgataga cacgggacac attagcacgt ataaattgcc 60 aaaattacca gagattaaaa catatgactg atttgaggag gatgaataga atggaactaa 120 cattacaaga ttttgagtat aacgaggata tgattgacgt atatgattta gatgatacgt 180 tagtgtttta tactagtgag aaaataggga gtagtac 217 <210> 690 <211> 217 <212> DNA <213> Artificial Sequence <400> 690 tgtcctcatt ttcctcaagt gctctaatct caatgctacg cgtctccgtt ttcatcatta 60 gtagcctcct tattttgatt gtttgtttct cgtgaaacat taatacgtga gcctgtcatt 120 ctagaaatct gactctcgtc tgtttcagga taaccatagt aggcgcgtac ctcgttaggt 180 ttaagatact caatgccttt ggctgtaccc tcaaaca 217 <210> 691 <211> 217 <212> DNA <213> Artificial Sequence <400> 691 atatacgcaa gagatgttta tccatgcgcc tgacggaatc gcactatcta ctgtagtacc 60 atacctactt actagaattg caccatccta gcgcacttct agtagtagcc tgttcattcc 120 agaacctaga tgaatgagtg ttacgttatt caatggtcta gcccaaactg gtagaggttg 180 gttaatgaca tattgacctg cgctaagttg gtttatg 217 <210> 692 <211> 216 <212> DNA <213> Artificial Sequence <400> 692 aataaacaat tctttttcag ggataggaat aacccacgta acagcggtca agtcatttac 60 tcgtgctagg tctataccaa taaatacttc acgccctgtg atgtcaaact cctcgtctgt 120 gtacgccatt tcccactcgt ctacagaaat gtatgacgtt gcttggtccg caacccaaaa 180 attaagctcc ttagttagga agttggtgag attacc 216 <210> 693 <211> 216 <212> DNA <213> Artificial Sequence <400> 693 aggcacaaaa gcgcgctatt gaaatgagtt ctcaggagtt cggtgaaaac tctaaagaag 60 ttgaggaggc tagaatctcc ctatctaact tagagtcaca ggctaaatta tcaagtaaag 120 ctcttaaatc aatggagaac gctagtgatg gacttagtga catcaaaggt ggagcagacg 180 aggctacaga tggggtaggt ggactattag atggtg 216 <210> 694 <211> 216 <212> DNA <213> Artificial Sequence <400> 694 tagcgcaggt caatatgtca ttaaccaacc tctaccagtt tgggctagac cattgaataa 60 cgtaacactc attcatcaag gttctggact gaacaggcta ctactagaag tgcgcaagga 120 tggtgcaatt ctagtaagta ggtatggtac tacagtagat agtgcgattc cgtcaggcgc 180 atggataaac atctcttgcg tatatgcggg tcaaga 216 <210> 695 <211> 216 <212> DNA <213> Artificial Sequence <400> 695 tcctgaaaat agtttgtcca tttcatagta aatattttgc gcctctgata gtgtcttaca 60 ccatacatct acctgtatgg ttatctccct cattaggggg ttattacttg cataagagtc 120 gtgagtatat ccaatctcag taattcgccc taatggtaag ttaggaattg tttgctccgc 180 ctcaggaaca aagtttacgt accagtctat atctgg 216 <210> 696 <211> 216 <212> DNA <213> Artificial Sequence <400> 696 ttgtgcgatt caatcaattc aattgccgca tatccccacg agttccatcc gccacctacg 60 tcataaaagc ccgcgtttgt gcgtgctgat tgaattactc gcccgttacc tactacgtgc 120 gagaagaacc cactgttgac gggtctgcgc atatgatagt ctgcctcgtt ttgcgctgta 180 gatgatgaat tccccgtact gtgtacgtga atttgt 216 <210> 697 <211> 216 <212> DNA <213> Artificial Sequence <400> 697 catatactct atgtgtgcgt agtttcttaa ccattgatgg tgacttgact ttatacacaa 60 tatctgatgg gatgagtttg ttgtcacgat taatagcaac gctgtgttct ttgagtagct 120 catttaattc ctcagtgttt ctatatccca caatcgcatt ataagaccgt ccacctaaat 180 actgtttctc ttctatacag tagcgttctc taaaag 216 <210> 698 <211> 216 <212> DNA <213> Artificial Sequence <400> 698 tagcgcaggt caatatgtca ttaaccaacc tctaccagtt tgggctagac cattgaataa 60 cgtaacactc attcatcaag gttctggaat gaacaggcta ctactagaag tgcgcaagga 120 tggtgcactt ctagtaagta ggtatggtac tacagtagat agtgcgattc cgtcaggcgc 180 atggataaac atctcttgcg tatatgcggg tcaaga 216 <210> 699 <211> 216 <212> DNA <213> Artificial Sequence <400> 699 taaaaacaac caatggtatt atgtaactaa gaactcaggt aagaaaatac ctgcctcagg 60 atgggtcagt ggatattacc tacaaaaccc taaacgtgtg gaacacaaga agaaagagac 120 ctactctatt gttgcaaaaa tgcaggtgac agattcaaga ttcacatgga tgggaacagg 180 taaatctaaa gaaagtaaaa acccatttaa agcagg 216 <210> 700 <211> 216 <212> DNA <213> Artificial Sequence <400> 700 cacatgattt tcgttcaaag ttagactagc tttatgtctc ttgtgatgat atagcgttta 60 atgatacgtg gtgcgttctc aatatcaggg tcagtaccaa tttcactata tgatagacta 120 ttgtagtgtc ctgaaaatag tttgtccatt tcatagtaaa tattttgcgc ctctgatagt 180 gtcttacacc atacatctac ctgtatggtt atctcc 216 <210> 701 <211> 216 <212> DNA <213> Artificial Sequence <400> 701 gtaacatcag cctgtgtcgc tttgccgtct ttgaatgctt gaaaaacgtc tcttgttttc 60 tgagaaaaca tatccatgtt gtcatctatc cgtccgtcaa caatagagat accaatttct 120 tttactaggt cgttcacctt atcaaggtta tatgctccac cgtcaagacc cgcaagcatt 180 gtactaaatg cctcatctgc tgtatatccc atttgt 216 <210> 702 <211> 216 <212> DNA <213> Artificial Sequence <400> 702 cattctcgca tatcctgata aggtactagc aatgtaaata gagttttgtg ttccgtcttg 60 tgagtttact aactccatac caaaacgaat taaaggtata ccaaacactt tagctatttg 120 ttttgtgcta aaggtattag actgaattag tttcaatagg tctgtattaa ccgtaaatgt 180 ttcatactct tgtgtgctgt ccaatacgag tacact 216 <210> 703 <211> 216 <212> DNA <213> Artificial Sequence <400> 703 ttgccaaact gtaggacttt accgttttcg ttcataacag caatcatacc gttttcttct 60 gcgttggtga tttcaaagat tgggtaacat ttccacgttc cataattggt aacaggtaca 120 gtctttagaa actccttaac agaagccacg tatgtcccat ctgtgccacg tgttagcatt 180 ggtctgttaa taacaacgtg tgcattacca tataca 216 <210> 704 <211> 216 <212> DNA <213> Artificial Sequence <400> 704 cttagtatca taatgcaact ctacattatg atactctttc atataggttt ttgcataatc 60 aaacaaacgc tctggacact taaaactata tgagccacca tctgcacatt tacaaattac 120 atgttcttct atactactat tgacaaacca attcacacac tctggcggat agcctagcac 180 aattccaagt gcataatctt ctccgtgttt tcttga 216 <210> 705 <211> 216 <212> DNA <213> Artificial Sequence <400> 705 ttatatgcga ttaaacccac ctactaaaca attacaagtg gatatacgag cgggcaaggt 60 ccttcacttt aacaaccctc tattgacaag agccgtgtac aacgcattta caaaagagtc 120 aaacgatgta attatgattg ataaacaagt taaccgcaac aagattgacc ctcttgacgc 180 gcttataaac gcgtacagtg aagcatactt ttatga 216 <210> 706 <211> 216 <212> DNA <213> Artificial Sequence <400> 706 caccatctaa tagtccacct accccatctg tagcctcgtc tgctccacct ttgatgtcac 60 taagtccatc actagcgttc tccattgagt taagagcttt acttgataat ttagcctgtg 120 actctaattt agatagggag attctagcct cctcaacttc tttagagttt tcaccgaact 180 cctgagaact catttcaata gcgcgctttt gtgcct 216 <210> 707 <211> 216 <212> DNA <213> Artificial Sequence <400> 707 gattaccgcg ccacctttta gagacattac accatctaat agtccaccta ccccatctgt 60 agcctcgtct gctccacctt tgatgtcact aagtccatca ctagcgttct ccattgattt 120 aagagctgta cttgataatt tagcctgtga ctctaattta gatagggaga ttctagcctc 180 ctcaacttct ttagagtttt caccgaactc ctgaga 216 <210> 708 <211> 216 <212> DNA <213> Artificial Sequence <400> 708 gtcaaaacat atagttgacc gtctccgttg aacacggggt actctttgcc aaacctccaa 60 tttacactat taaactcacc tgtgtaaatt aaaacatctc cgacttttag ttcattaact 120 ttaaccagtg ttttcctcct taatattcaa cactaacaat gtagtacggt tgtattacta 180 cattcacggg cacagagctt agtagcataa tctgaa 216 <210> 709 <211> 216 <212> DNA <213> Artificial Sequence <400> 709 tacttgataa tttagcctgt gactctaatt tagataggga gattctagcc tcctcaactt 60 ctttagagtt ttcaccgaac tcctgagacc tcatttcaat agcgcgcttt tgtgcctcaa 120 tagctttctc agttaaggag attgaacgtt ttagaccctc ctgtttagcc tcaagtgcgc 180 ccgctgagtc ccctgcgtct tttagtgctt ttactt 216 <210> 710 <211> 216 <212> DNA <213> Artificial Sequence <400> 710 attattgttg ctgattgcgt ctattgtgac ggaatattta actcctgctg gcaagtagtt 60 ggttaataag tcattgctat tatagtctct tctgttagtt gatgagtcgt taaacaacac 120 tcgcatggtc ccgtttgaat attctatagt cgcaccattt cctgtccaac cattaatagt 180 ggggtctttc gagaaatcat aattcaatac taaatt 216 <210> 711 <211> 216 <212> DNA <213> Artificial Sequence <400> 711 tagttttaag tgtccagagc gtttgtttga ttatgcaaaa acctatatga aagagtatca 60 taatgtagag ttgcattatg atactaagac agaagatatt tttgttataa gaaatgatat 120 gttcctatgg gaataatgtc taataaggag gaaaaataaa tgattactgt aacgattaat 180 aaatggcgaa aagcaaaagt gacacctgtt attgtt 216 <210> 712 <211> 216 <212> DNA <213> Artificial Sequence <400> 712 attattgttg ctgaatgcgt ctattgtgac ggaatattta actcctgctg gcaagtagtt 60 ggttaataag tcattgctat aatagactat tctgttagtt gatgagtcgt taaacaacac 120 tcgcatgttc ccgtttgaat attctatagt cgcaccattt cctgtccaac cattaatagt 180 ggggtctttc gagaaatcat aattcaatac taaatt 216 <210> 713 <211> 216 <212> DNA <213> Artificial Sequence <400> 713 aataaacaat tctttttcag ggataggaat aacccacgta acagcggtca agtcatttac 60 tcgtgctagg tctataccaa taaatactac acgccctgtg atgtcaaact cctcgtctgt 120 gtacgccttt tcccactcgt ctacagaaat gtatgacgtt gcttggtccg caacccaaaa 180 attaagctcc ttagttagga agttggtgag attacc 216 <210> 714 <211> 216 <212> DNA <213> Artificial Sequence <400> 714 tggacaatga aatctaagga agtcctacac attcgtgcag gttccaagac tagttacaag 60 tcatacggtc tgttacctaa gggcgtcacg tttgaaacaa ccaaacgtca aacgggtcaa 120 aagattaata aaaacaacca atggtattat gtaactaaga actcaggtaa gaaaatacct 180 gcctcaggat gggtcagtgg atattaccta caaaac 216 <210> 715 <211> 216 <212> DNA <213> Artificial Sequence <400> 715 gttacccaat ctttgaaatc accaacgcag aagaaaacgg tatgattgct gttatgaacg 60 aaaacggtaa agtcctacag tttggcaagg aagaaaacaa agacgctaca gagccaatta 120 aagacgaaat tggtctaaat gaaaactaca gaggtacgaa attgccaact ggtttcaccg 180 tcaatagtgg gcacgtatca cagtacccaa atacgt 216 <210> 716 <211> 216 <212> DNA <213> Artificial Sequence <400> 716 acaaatggga tatacagcag atgaggcatt tagtacaatg cttgcgggtc ttgacggtgg 60 agcatataac cttgataagg tgaacgacat agtaaaagaa attggtatct ctattgttga 120 cggacggcta gatgacaaca tggatatgtt ttctcagaaa acaagagacg tttttcaagc 180 attcaaagac ggcaaagcga cacaggctga tgttac 216 <210> 717 <211> 216 <212> DNA <213> Artificial Sequence <400> 717 tatgacacct gttattaatg aaagcaatga gacccgtacc attaccatct gcatggtcaa 60 cggacgctct tacacatata agggttcccc agagtttgtt attgaacgta tgcaaacagg 120 agaggttatt cagattatgc tactaagctc tgtgcccgtg aatgtagtaa tacaaccgta 180 ctacattgtt agtgttgaat attaaggagg aaaaca 216 <210> 718 <211> 216 <212> DNA <213> Artificial Sequence <400> 718 tcgttttggt atggagttag taaactcaca agacggaaca caaaactcta tttacattgc 60 tagtacctta tcaggatatg cgagaatgtt atgtgatgag ttaaatctta aattaaatat 120 tgacgtggaa ctagactttg ctagtttatt aaacgataca ttagacgaac gcaaaaaacg 180 aatgtttgag ggtacagcca aaggcattga gtatct 216 <210> 719 <211> 216 <212> DNA <213> Artificial Sequence <400> 719 tcttgacccg catatacgca agagatgttt atccatgcgc ctgacggaat cgcactatct 60 actgtagtac catacctact tactagaagt gcaccatcct tgcgcacttc tagtagtagc 120 ctgttcagtc cagaaccttg atgaatgagt gttacgttat tcaatggtct agcccaaact 180 ggtagaggtt ggttaatgac atattgacct gcgcta 216 <210> 720 <211> 216 <212> DNA <213> Artificial Sequence <400> 720 caccatctaa tagtccacct accccatctg tagcctcgtc tgctccacct ttgatgtcac 60 taagtccatc actagcgttc tccattgagt taagagcttt acttgataat ttagcctgtg 120 actctaagtt agatagggag attctagcct cctcaacttc tttagagttt tcaccgaact 180 cctgagaact catttcaata gcgcgctttt gtgcct 216 <210> 721 <211> 216 <212> DNA <213> Artificial Sequence <400> 721 aataaacaat tctttttcag ggataggaat aacccacgta acagcggtca agtcatttac 60 tcgtgctagg tctataccaa taaatactac acgccctgtg atgtcaaact cctcgtctgt 120 gtacgccatt tcccactcgt ctacagaaat gtatgacgtt gcttggtccg caacccaaaa 180 attaagctcc ttagttagga agttggtgag attacc 216 <210> 722 <211> 216 <212> DNA <213> Artificial Sequence <400> 722 gtaacatcag cctgtgtcgc tttgccgtct ttgaatgctt gaaaaacgtc tcttgttttc 60 tgagaaaaca tatccatgtt gtcatctatc cgtccgtcaa caatagagat accaatttct 120 tttactatgt cgttcacctt atcaaggtta tatgctccac cgtcaagacc cgcaagcatt 180 gtactaaatg cctcatctgc tgtatatccc atttgt 216 <210> 723 <211> 216 <212> DNA <213> Artificial Sequence <400> 723 cttttagaga acgctactgt atagaagaga aacagtattt aggtggacgg tcttataatg 60 cgattgtggg atatagaaac actgaggact taaatgagct actcaaagaa cacagcgttg 120 ctattaatcg tgacaacaaa ctcatcccat cagatattgt gtataaagtc aagtcaccat 180 caatggttaa gaaactacgc acacatagag tatatg 216 <210> 724 <211> 215 <212> DNA <213> Artificial Sequence <400> 724 gcggcaattg aattgattga atcgcacaaa accaaagaag agtttatgaa agactataag 60 ctactagtag aattaattcg tctattatgt gatgaagcgg gactacctaa gacgctagac 120 caagggacta caggtgtcat ttctcacgca tatgcaacgg cacatcaacc aaacaatggt 180 tctgaccata ttgaccccta tccatacttg cgtaa 215 <210> 725 <211> 215 <212> DNA <213> Artificial Sequence <400> 725 cccacatttc cataactgta acccatccgt caccactacc attataaccg ttgctagggt 60 cattcatgtc aacaagaacc catccaccca ttaaattaga tggtaggaaa aacccaccat 120 attcgcggac ccatattgaa tggagtaagt tatcttctgt aggtatagtt ttcttagtca 180 tatttacaag tttcataagc agttacctcc tataa 215 <210> 726 <211> 215 <212> DNA <213> Artificial Sequence <400> 726 gagttaaatc ttaaattaaa tattgacgtg gaactagact ttgctagttt attaaacgat 60 acattagacg aacgcaaaaa acgaatgatt gagggtacag ccaaaggcat tgagtatctt 120 aaacctaacg aggtacgcgc ctactatggt tatcctgaaa cagacgagag tcagttttct 180 agaatgacag gctcacgtat taatgtttca cgtga 215 <210> 727 <211> 215 <212> DNA <213> Artificial Sequence <400> 727 gtacattttg atgataataa ttaaataaca aaaataataa aataacaaag ggtggtgtac 60 ggttttttaa gcgttggggg acaagggatt gagacatttt tggtacaaat gtacacgatt 120 gtaccatttt tttggtacgg ttaaatacca cgtgtgtcgt ggggtttact tatgttcttt 180 tattctttat tattttttat tactttatat aaaga 215 <210> 728 <211> 215 <212> DNA <213> Artificial Sequence <400> 728 agcacccgca aagtgtccgc caaagcgcgc gtcatattca gccttaccct tttcattcac 60 cttaatgcgt gtagccgtaa tttgttgatt aaatacctct ggttctaaat tataagggtt 120 caattcatca atgaaaatca actgtttgtc aactagtaac gcactattaa actcaccttt 180 tgtgttaaat gcgcggttag atgggagttc tgtgt 215 <210> 729 <211> 215 <212> DNA <213> Artificial Sequence <400> 729 ttaaaggaac acagtacatc ataggacaaa actacacgca tagtatttat gtaaaaaaca 60 acggtgataa acctatttct atttcaatca gaatgggagt gggtaaaaca atagatccca 120 atgagagtaa gtacattagc tttgaaccaa cgtacaccat gggttcaaca gatatggggt 180 ttaatttcta ctctgacgca acaggggact tacct 215 <210> 730 <211> 215 <212> DNA <213> Artificial Sequence <400> 730 ggatggagta caacacgtcc aacacctcaa attggtatgt ggttgtgggt aaggagtaga 60 aatacgcttt caaatggtac gtatacacat tgggtagtaa ctagctcata cacgggtaga 120 gactcaattt ttattagtgc tacagctcca agtaacccaa ctacagggac attatggcaa 180 aaacctaatg accctactgt gctaaaatgg aacgg 215 <210> 731 <211> 215 <212> DNA <213> Artificial Sequence <400> 731 ctgtataggc tactgatgtt gtaccatcag tgtactccca cgttgtacgt gtccataggt 60 atttaccttt ttctagagtt gggatgggtg tactccatcc tgatgtaggt tcatcaacgc 120 ttgaggtatt gattgcccac tctgttttag ttgatttgac ggaggcgccc ttttgtcccg 180 gtgttctcat ccacgtgtac ttacttgggt ccgtg 215 <210> 732 <211> 215 <212> DNA <213> Artificial Sequence <400> 732 ttgaaataga aataggttta tcaccgttgt tttttacata tatactatgc gtgtagtttt 60 gtcctatgat gtactgtgtt cctttaagtt ctaacacacc tatgagatta ttacttgtgt 120 tcttagttac cttataattg acagcattac tagcacccca ttctggtaca gaaacccctg 180 ttgttcgtgt aaattcacta gttccgtcag acact 215 <210> 733 <211> 215 <212> DNA <213> Artificial Sequence <400> 733 tctggacatt tacagataat agtaaccaaa caacctactc agtggcgcgc tttggtcagg 60 atggtattag tgtgactggt actcaatcag agtatgtaca aacaactagt tctgtagaac 120 ctacctctgg atggagtaca acacgtccaa cacctcaaat tggtatgtgg ttgtgggtaa 180 ggagtagaaa tacgctttca aatggtacgt ataca 215 <210> 734 <211> 215 <212> DNA <213> Artificial Sequence <400> 734 caacaaatta cggctacacg cattaaggtg aatgaaaagg gtaaggctga atatgacgcg 60 cgctttggcg gacactttgc gggtgctcgt aatgatgtat ttaaagtacg tgacgcctca 120 gatggttcgt taagacgtat tttgccaatt attttcaata agcaagtgac aaaaggtgat 180 gacaaagtaa cgtttatgcg tcaatttaac cctga 215 <210> 735 <211> 215 <212> DNA <213> Artificial Sequence <400> 735 ggtaaaattg cctattaata cattgtttgg tgccacaggt gcagagttta atgggttata 60 tgacccacgt tttcaatttc taacatgggt gattgggcaa ttaattatgg ctgacttcta 120 cgagggaatt agggaccatg ttaccatgtt acagagcaac acagactgtc acgcctacat 180 tcctcatgat gaggaggctg aacgtattac agacg 215 <210> 736 <211> 215 <212> DNA <213> Artificial Sequence <400> 736 tacaggtgtc atttctcacg catatgcaac ggcacatcaa ccaaacaatg gttctgacca 60 tattgacccc tatccatact tgcgtaactg gggaattagt aaagagcagt ttgctaaaga 120 cattaaaaat gggtttggtg gaaatagttc caatactgac aacaaaccta aaccaaaacc 180 acaaccgtct aaaccaaaaa tcacagacac acgtg 215 <210> 737 <211> 215 <212> DNA <213> Artificial Sequence <400> 737 ctgtataggc tactgatgtt gtaccatcag tgtactccca cgttgtacgg gtccataggt 60 atttaccttt ttctagagtt gggatgggtg tactccatcc tgatgtaggt tcatcaacgc 120 ttgaggtctt gattgcccac tctggtttag ttgatttgac agaggcgcca ttttgtcccg 180 ttgttctcat ccacgtgtac ttacttgggt ccgtg 215 <210> 738 <211> 215 <212> DNA <213> Artificial Sequence <400> 738 cctgtatact aaaagcatta gttgcccctg cggttatacc ctcaaattta tacgttgaag 60 gtgtgtcacc ttgttttatt gtttgccatg tactgagagc gtcaaaatta cctaccctaa 120 ttaacccttt attgttgctg aatgcgtcta ttgtgacgga atatttaact cctgctggca 180 agtagttggt taataagtca ttgctataat agact 215 <210> 739 <211> 215 <212> DNA <213> Artificial Sequence <400> 739 tcacgtgaaa cattaatacg tgagcctgtc attctagaaa actgactctc gtctgtttca 60 ggataaccat agtaggcgcg tacctcggta ggtttaagat actcaatgcc tttggctgta 120 ccctcaaaca ttcgtttttt gcgttcgtct aatgtatcgt ttaataaact agcaaagtct 180 agttccacgt caatatttaa tttaagattt aactc 215 <210> 740 <211> 215 <212> DNA <213> Artificial Sequence <400> 740 tcacgtgaaa cattaatacg tgagcctgtc attctagaaa actgactctc gtctgtttca 60 ggataaccat agtaggcgcg tacctcggta ggtttaagat actcaatgcc tttggctgta 120 ccctcaatca ttcgtttttt gcgttcgtct aatgtatcgt ttaataaact agcaaagtct 180 agttccacgt caatatttaa tttaagattt aactc 215 <210> 741 <211> 215 <212> DNA <213> Artificial Sequence <400> 741 ggtaaaattg cctattaata cattgtttcg tgccacaggt gcagagttta atggtttata 60 tgacccacgt tttcaatttc taacatgggt gattgggcaa ttaataatgg ctgaaatcta 120 cgagggactt agggaccatg ttacaatgtt acagagcaac acagactgtc acgcctacat 180 tcctcatgat gaggaggctg aacgtattac agacg 215 <210> 742 <211> 214 <212> DNA <213> Artificial Sequence <400> 742 tatatgacac ctgttattaa tgaaaccaat gagacccgta ccattaccat cagcatggtc 60 aacggacgct cttacacata taaggggtcc ccagagtttg ttattgaacg tatgcaaaca 120 ggagaggttt ttcagattat gctactaagc tctgtgcccg tgaatgtagt aatacaaccg 180 tactacattg ttagtgttga atattaagga ggaa 214 <210> 743 <211> 214 <212> DNA <213> Artificial Sequence <400> 743 attccccgta ctgtgtacgt gaatttgtcc atacggtctt acccctactt gtggtaaacc 60 tgagcgcatt tgtttttcaa ttttcattga atcattctcc tttctatctc taatcattat 120 aacacaataa aggaggctta agcctcctta ggttatgcta aacgcccttg acgtctgtta 180 gataccattt gtccgcgttg cttatcttta gtta 214 <210> 744 <211> 214 <212> DNA <213> Artificial Sequence <400> 744 acattcagtt ccaacccaaa ctctggtggc aatggctacg gtgcagagta tagtagtaca 60 ggtttgcgtc taacagattc gcgcgtgtca ttaggtaact caaagctgga aattcatgat 120 ttaattaaag ttgaaacaac catgttggac cctgcgtcag gttggcaaag atatagtgat 180 gttatgggat acactaacac acctacagcc acgc 214 <210> 745 <211> 214 <212> DNA <213> Artificial Sequence <400> 745 tatatgacac ctgttattaa tgaaagcaat gagacccgta ccattaccat ctgcatggtc 60 cacggacgct cgtacacata tacgggttcc ccagagttgg ttattgaacg tctgcaaaca 120 tgagaggatt ttcagattat gctactaagc tctgtgcccg tgaatgtagt aatacaaccg 180 tactacattg ttagtgttga atattaagga ggaa 214 <210> 746 <211> 214 <212> DNA <213> Artificial Sequence <400> 746 gataggtcta tcacctttag acaattcctc tactaatcta ttacacgttt ctttatattg 60 atagccaata acaacgcgtt ctcctttagt ttcttctagt atgtctttta gacggtctgt 120 cttgctgatt ttagctactt tacttacata tggtataaaa ccattagacg caaccctaag 180 tgcgttaaac agcttgctag ggttatctaa ttca 214 <210> 747 <211> 214 <212> DNA <213> Artificial Sequence <400> 747 ctgtatacta aaagcattag ttgcccctgc ggttataccc tcaaatttat acgttgaagg 60 tgtgtcacct tgttttattg tttgccatgt actgagagcg tcaaaattac ctaccctaat 120 taacccagta ttgttgctga atgcgtctat tgtgacggaa tatttaactc ctgctggcaa 180 gtagttggtt aataagtcat tgctataata gact 214 <210> 748 <211> 214 <212> DNA <213> Artificial Sequence <400> 748 tattgaacgt atgcaaacag gagaggtttt tcagattatg ctactaagct ctgtgcccgt 60 gaatgtagta atacaaccgt actacagtgt tagtgttgaa tattaaggag gaaaacaatg 120 gttaaagtta atgaactaaa agtcggagat gttttaattt acacaggtga gtttaatagt 180 gtaaattgga ggtttggcaa agagtacccc gtgt 214 <210> 749 <211> 214 <212> DNA <213> Artificial Sequence <400> 749 acgcgcgaat ctgttagacg caaacctgta ctactatact ctgcaccgta gccattgcca 60 ccagagtttg ggttggaact gaatgtgtgt agatttagtg cgtcagggtc tagatataat 120 tgattgtagt ttgtgttacc tgcttcatta gttgtagcca tgagtatata gtttgctgcc 180 ataatttgac gatgtgcgtt tttaaacact cctg 214 <210> 750 <211> 214 <212> DNA <213> Artificial Sequence <400> 750 tgtagtacgg ttgtattact acattcacgg gcacagagct tagtagcata atctgaaaaa 60 cctctcctgt ttgcatacgt tcaataccaa actctgggga acccttatat gtgtaagagc 120 gtccgttgac catgcagatg gtaatggtac gggtctcatt gctttcatta ataacaggtg 180 tcatataatc atctaccttt ttcacgtttc caaa 214 <210> 751 <211> 214 <212> DNA <213> Artificial Sequence <400> 751 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgagga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaattc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgctcctct tttg 214 <210> 752 <211> 214 <212> DNA <213> Artificial Sequence <400> 752 cacagcgttg ctattaaacg tgacaacaaa ctcatcccat cagatattgt gtataaagtc 60 aagtcaccat caatggttaa gaaactacgc acacatagag tatatgaaac agactcaggt 120 gacataagtg aattagataa ccctagcaag ctgtttaacg cacttagggt tgcgtctaat 180 ggttttatac catatgtaag taaagtagct aaaa 214 <210> 753 <211> 214 <212> DNA <213> Artificial Sequence <400> 753 ctgtatacta aaagcattag ttgcccctgc ggttataccc tcaattttat acgttgaagg 60 tgtgtcacct tgttttattg tttgccatgt actgagagcg tcaaaattac ctaccctaat 120 taacccaata ttgttgctga atgcgtctat tgtgacggaa tatttaactc ctgctggcaa 180 gtagttggtt aataagtcat tgctataata gact 214 <210> 754 <211> 214 <212> DNA <213> Artificial Sequence <400> 754 acaacgggtg gtggtattgt tcagaaagag gctaacgata gaacacccta tagacaatat 60 tccaaacagg ggtattgtga aatttcttcc cgtcctgacg gtcagtgtga ttgggaggat 120 atgttaactt gggttttggc gtttattgag acaaacaatt tagacgtaca aggtatttgt 180 tatgaccctg cacagtctca attaattacc acaa 214 <210> 755 <211> 214 <212> DNA <213> Artificial Sequence <400> 755 attccccgta ctgtgtacgt gaatttgtcc atacggtctt acccctactt gtggtaaacc 60 tgagcgcatt tgtttttcaa ttttcagtga atcattctcc tttctatctc taatcattat 120 aacacaataa aggaggctta agcctcctta ggttatgcta aacgcccttg acgtctgtta 180 gataccattt gtccgcgttg cttatcttta gtta 214 <210> 756 <211> 214 <212> DNA <213> Artificial Sequence <400> 756 ttcctcctta atattcaaca ctaacaatgt agtacggttg tattactaca ttcacgggca 60 cagagcttag tagcataatc tgaaaatcct ctcctgtttg catacgttca ataacaaact 120 ctggggaccc cttatatgtg taagagcgtc cgttgaccat gcagatggta atggtacggg 180 tctcattgct ttcattaata acaggtgtca tata 214 <210> 757 <211> 214 <212> DNA <213> Artificial Sequence <400> 757 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgagga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaagtc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgctcctct tttg 214 <210> 758 <211> 214 <212> DNA <213> Artificial Sequence <400> 758 ttgtggtaat taattgagac tgtgcagggt cataacaaat accttgtacg tctaaattgt 60 ttgtctcaat aaacgccaaa acccaagtta acatatcctc ccaatcacac tgaccgtcag 120 gacgggacga aatttcacaa tacccctgtt tggaatattg tctatagggt gttctatcgt 180 tagcctcttt ctgaacaata ccaccacccg ttgt 214 <210> 759 <211> 213 <212> DNA <213> Artificial Sequence <400> 759 tgacaagttc gtataccttg tccccaactt tacctaagaa cgtacctact ttattatcac 60 tatcaccact tttaaactct tgcgcgtgtg ggtaaatgac agagtatagt agaaattcac 120 gtacattatt agaaacatag tgccaaatgt tcgtatcttt gttcaatacc catgcactct 180 taccatctgt ggataagatg agggtagtat tat 213 <210> 760 <211> 213 <212> DNA <213> Artificial Sequence <400> 760 tgcgtgagca aggtgttgat gaccgaacac tcacattata tgctaactat gcaatgctac 60 aggtggcaca acttctaaaa cttggttatg ttagtataga cgagtttatt gaaaaggcta 120 gagaggactt ataggaggta actgcttatg aaacttgtaa atatgactaa gaaaactata 180 cctacagaag ataacttact ccattcaata tgg 213 <210> 761 <211> 213 <212> DNA <213> Artificial Sequence <400> 761 ttgtcaacta gtaacgcact attaaactca ccttttgtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacaatggt gagcctatga ttttggtcat tagaatagac 120 tttccatgtc ctccgttgcg tgtaccgcgt gagacaacaa tttgagcatg aacagcctca 180 ggtttgttct catagacgca tgaccctatg aac 213 <210> 762 <211> 213 <212> DNA <213> Artificial Sequence <400> 762 caacatcagt agcctataca gtgaactata ttcctgtaga tggctcaacc ggtaatggtg 60 tgaaatctat cgctgttact tacgctgtag gtacctcagg tacaacagca ccatccacag 120 gttggcacgc aacaccacca aatgtaacag gtggtcaata cctatggaca cgtattatct 180 ggacatttac agataatagt aaccaaacaa cct 213 <210> 763 <211> 213 <212> DNA <213> Artificial Sequence <400> 763 ggagtacaac acgtccaaca cctcaaattg gtatgtggtt gtgggtaagg agtagaaata 60 cgctttcaaa tgctacgtat acaaagtggg taggaactag ctcatacacg ggtagagacg 120 caaattttat tagtgctcca gctccaagta acccaactac agggacatta tggcaaaaac 180 cgaatgaccc tactgtgcta acatggaacg gta 213 <210> 764 <211> 213 <212> DNA <213> Artificial Sequence <400> 764 ataaagaaaa aaataaatac aatatataat atatacaaaa actgatataa tggtgtttat 60 ggtaggtgga aaatgtaatt gttttctata agagctgagg tcatcccaca acactacaat 120 ggttaaatca gggttgaaac attgatacac aaggcgtaaa acaggtttgt acaaaaagtg 180 tacacggttt ttgaatgtgt acaataataa caa 213 <210> 765 <211> 213 <212> DNA <213> Artificial Sequence <400> 765 aacaaggtca ccctcattac ccgtgtgctc aaatagtcca ctattaaagg ctaaatcaat 60 aacaggtgtt ttactacgta ctagttcctc acgcatttcc ttagcctcat cagatagcgt 120 ccacacacac tcgtctgcgg taacgtcctc tctgcgtttc aatagttcag catactcctg 180 tacacaccat ctaataaact cagctttctc atg 213 <210> 766 <211> 213 <212> DNA <213> Artificial Sequence <400> 766 gcacccagtt gtctgtactt gtgtttgtga ttgagacttt tccatcttcg cgcgtactat 60 catagtaggt aacacgcaca attaagtctg ttgttgctag actaccagtc caccccttag 120 agatgaatac actccctgat acagtgtacg ttgtaccgcg caaagcactg tagccatttg 180 ataggtatgc aggacgtatt gttgacactg ctg 213 <210> 767 <211> 213 <212> DNA <213> Artificial Sequence <400> 767 ttgtcaacta gtaacgcact attaaactca ccttttgtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacactggt gagcctatga ttttggtcat tagaatagac 120 tttccatttc ctccgttgcg tgtaccgcgt gagacaacaa tttgagcatg aacagcctca 180 ggtttgttct catagacgca tgaccctatg aac 213 <210> 768 <211> 213 <212> DNA <213> Artificial Sequence <400> 768 tttgtccgcg ttgcttatct ttagttaaag cagggtttag ttccgcagta actttacgtt 60 tgtctaagta gacgtccgtg tccttgtcta gtaatgcttg taacagtgcg tttgtttgtt 120 gttgctgtac aatcaattga gcaattagct catcattaga accctgacca gctaccacgg 180 ttgtttgtga tacacctaac cgcttttgtg cct 213 <210> 769 <211> 213 <212> DNA <213> Artificial Sequence <400> 769 cagcagtgtc aacaatacgt cctgcatacc tatcaaatgg ctacagtgct ttgcgcggta 60 caacgtacac tgtatcaggg agtgtcttca tctctaaggg gtggactggt agtctagcaa 120 caacagaatt aattgtgcgt gttacctact atgatagtac gcgcgaagat ggaaaagtct 180 caatcacaaa cacaagtaca gacaactggg tgc 213 <210> 770 <211> 213 <212> DNA <213> Artificial Sequence <400> 770 agtttatcat ttgtgtcgtt tttaaagata gcgtcaggaa gtacaattac ctctttacca 60 aacaatgttt taccacttgc cattgctacg tttggttgaa taatgtatcg tccgtctgcg 120 tctttcatcg tatccaattg agcaaatgcg ctttgagaaa caaaaactcg ttgattgtaa 180 gcagggtcaa ttgttacgtt tgacgctgtt ttc 213 <210> 771 <211> 213 <212> DNA <213> Artificial Sequence <400> 771 actcgtctgc ggtaacgtcc tctctgcgtt tcaatagttc agcatactcc tgtacacacc 60 atctaataaa ctcagctttc tcatggtcgt tgtttagtgc gtctctcatc tcagtagaca 120 catcagggtt aaattgacgc ataaacgtta ctttgtcatc accttttgtc acttgcttat 180 tgaaaataat tggcaaaata cgtcttaacg aac 213 <210> 772 <211> 213 <212> DNA <213> Artificial Sequence <400> 772 gtattatgac agtggggcag gacactcaag ctccttatgt ctctgttact tttgtatcag 60 atgacgcaga tggtaatgag gtatagatgg gactgactaa agttcgcttt gctcaccctg 120 acgttgcgtt gaatacctca gagggtggag gcactgaccc taatactgat actattgagg 180 ggtctgctat tagtgactca cgtggatatg tat 213 <210> 773 <211> 213 <212> DNA <213> Artificial Sequence <400> 773 aaacggacgt agttctaatg tacgcatgtt tagcgcaccg ttttgaaaat acgcacattc 60 accaaggtat ctgtacttat cgttcgttct atcgttgaaa tatccctctt taaattgagg 120 gttacctatg acaagttcgt ataccttgtc cccaacttta cctaagaacg tacctacttt 180 attatcacta tcaccacttt taaactcttg cgc 213 <210> 774 <211> 213 <212> DNA <213> Artificial Sequence <400> 774 gttgtttaga tgtttcattc ataaccttaa aggcgcctga tggtttccct ttttcgtcaa 60 gataaccgta ttcagatacc tcttgagttg cctgactgta aatagcgtaa gtattacaat 120 aaatgacgag catgccagcg tctagttttg aaattggtag ctgtttaagt tgtggaacaa 180 ggtcctcgta aatcaaccac ccttccttag taa 213 <210> 775 <211> 213 <212> DNA <213> Artificial Sequence <400> 775 ccatattgaa tggagtaagt tatcttctgt aggtatagtt ttcttagtca tatttacaag 60 tttcataagc agttacctcc tataattcct ctctagcctt ttcaataaac tcgtctatac 120 taacataccc aagttttaga agttgtgcca cctgtagcat tgcatagtta gcatataatg 180 tgagtgttcg gtcatcaaca ccttgctcac gca 213 <210> 776 <211> 213 <212> DNA <213> Artificial Sequence <400> 776 taagtatgct aaagcgggag taattacacc aatgatgaat cgtacccaga ataagatatt 60 gtccttgcta aacctcacgc gccaggtaat atttttcata tgtcagttcc cctttctaat 120 ctattatatc atatatttaa ccagtgatga atgccaaaat tgcacccact acaccagtga 180 taattgctcc tacggttgtt ctagtaagcc atg 213 <210> 777 <211> 213 <212> DNA <213> Artificial Sequence <400> 777 cgtatccaat tgagcaaatg cgctttgaga aacaaaaact cgttgattgt aagcagggtc 60 aattgttacg tttgacgctg ttttctattg atcaagagaa gttacttctg ttgcttcgaa 120 cttagctagt aactcagtca ttactgcttt attgattgtg ttcaacccaa tacgtgttaa 180 gtggcgagca atcaacgcaa ctaagtcagg gtc 213 <210> 778 <211> 213 <212> DNA <213> Artificial Sequence <400> 778 ttcccatcca tgtgaatctt gaatctgtca cctgcatttt tgcaacaata gagtaggtct 60 ctttcttctt gtgttccaca cgtttagtgt tttgtaggta atatccactg acccatcctg 120 aggcagggat tttcttacct gagttcttag ttacataata ccattggttg tttttaataa 180 tcttttgacc cgtttgacgt ttggttgttt caa 213 <210> 779 <211> 213 <212> DNA <213> Artificial Sequence <400> 779 cttgaaaagc tagagaaaaa aggagctgat taacacatgg tgcaaagcgg aaaaccagta 60 ggaaatatga agtttggttt aggtaatgac ggaaccgctg aactaggtaa tacacttgac 120 aaactaacaa aacaattcaa acaagctgaa agctccatga aggcaaacat caaagcgttt 180 gacggtgcct ctgatagtgt agaggcattg gaa 213 <210> 780 <211> 213 <212> DNA <213> Artificial Sequence <400> 780 attatgtgtt tcccatttgt ctatgaccat ttgctgttgt tccgttggta ttaacattat 60 attacctcct ccacattagt ctatcatgaa accatgtagg gttgttgtgt tgggtagtag 120 gttatatatt gttattattg tacacattca aaaaccgtgt acactttttg tacaaacctg 180 ttttacgcct tgtgtatcaa tgtttcaacc ctg 213 <210> 781 <211> 213 <212> DNA <213> Artificial Sequence <400> 781 ctgagcgcat ttgtttttca attttcattg aatcattctc ctttctatct ctaatcatta 60 taacacaaaa aaggaggctt aagcctcctt aggttatgct aaacgccctt gacgtctgtt 120 agataccctt tgtccgcgtt gcttatcttt agttaaagca gggtttagtt ccgcagtaac 180 tttacgtttg tctaagtaga cgtccgtgtc ctt 213 <210> 782 <211> 213 <212> DNA <213> Artificial Sequence <400> 782 taagtatgct aaagcgggag taattacacc aatgatgaat cgtacccaga ataagatatt 60 gtccttgcta aacctcacgc gccagttaat atttttcata tgtcagttcc cctttctaat 120 ctattatctc atatatttaa ccagtgatga atgccaaaat tgcacccact acaccagtga 180 taattgctcc tacggttgtt ctagtaagcc atg 213 <210> 783 <211> 213 <212> DNA <213> Artificial Sequence <400> 783 cagcagtgtc aacaatacgt cctgcatacc tatcaaatgg ctacagtgct ttgcgcggta 60 caacgtacac tgtatcaggg agtgtcttca tctctaaggg gtggactggt agtctagcaa 120 caacagactt aattgtgcgt gttacctact atgatagtac gcgcgaagat ggaaaagtct 180 caatcacaaa cacaagtaca gacaactggg tgc 213 <210> 784 <211> 213 <212> DNA <213> Artificial Sequence <400> 784 cgcgtcaaac gttccgtttt tcgtatctgc taaaggtaca ggtgaaacaa ccgtatcatt 60 gaatgttttc gacttacaag cgggtggagc atatagtgct gttttaggta ttaccgcaga 120 cgaaaattgt attatgacag tggggcagga cactcaagct ccttatgtct ctgttacttt 180 tgtatcagat gacgcagatg gtaatgaggt ata 213 <210> 785 <211> 213 <212> DNA <213> Artificial Sequence <400> 785 ttgtcaacta gtaacgcact attaaactca ccttttgtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacactggt gagcctatga ttttggtcat tagaatagac 120 tttccatgtc ctccgttgcg tgtaccgcgt gagacaacaa tttgagcatg aacagcctca 180 ggtttgttct catagacgca tgaccctatg aac 213 <210> 786 <211> 213 <212> DNA <213> Artificial Sequence <400> 786 taagtatgct aaagcgggag taattacacc aatgatgaat cgtacccaga ataagatatt 60 gtccttgcta aacctcacgc gccaggtaat atttttcata tgtcagttcc cctttctaat 120 ctattatctc atatatttaa ccagtgatga atgccaaaat tgcacccact acaccagtga 180 taattgctcc tacggttgtt ctagtaagcc atg 213 <210> 787 <211> 213 <212> DNA <213> Artificial Sequence <400> 787 tgcgtgagca aggtgttgat gaccgaacac tcacattata tgctaactat gcaatgctac 60 aggtggcaca acttctaaaa cttgggtatg ttagtataga cgagtttatt gaaaaggcta 120 gagaggactt ataggaggta actgcttatg aaacttgtaa atatgactaa gaaaactata 180 cctacagaag ataacttact ccattcaata tgg 213 <210> 788 <211> 212 <212> DNA <213> Artificial Sequence <400> 788 tgtacgtgtc cataggtatt tacctttttc tagagttggg atggttgtac tccatcctga 60 tgtaggttca tcaacgcttg aggtattgat tgcccactct gttttagttg atttgacaga 120 ggcgccagtt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctagggtc 180 gtgagtatag ttactatatt gacccatata ta 212 <210> 789 <211> 212 <212> DNA <213> Artificial Sequence <400> 789 tgtgctaaga accatgagtt aataccatca acaagaaacg catatttact tacagattga 60 ttaactgttt tacgttcttt tactttgtat gttttacctt ttacaaagtt tggcactggt 120 tgacccggtt ggtatttagt tgctttggcg cgtactttta ctttactacc tacagggaaa 180 tcacgtgtgt ctgtgatttt tggtttagac gg 212 <210> 790 <211> 212 <212> DNA <213> Artificial Sequence <400> 790 agtgctgttt taggtattac cgcagacgaa aatggtatta tgacagtggg gcaggacact 60 caagctcctt atgtctctgt tactattgta tcagatgacg cagatggtaa tgaggtatat 120 atgggactga ctaaagttcg ctttgctcac cctgacgttg cgttgaatac ctcagagggt 180 ggaggcactg accctaatac tgatactatt ga 212 <210> 791 <211> 212 <212> DNA <213> Artificial Sequence <400> 791 gggttacttg gagctgtagc actaataaaa attgagtctc tacccgtgta tgagctagtt 60 actacccaat ttgtatacgt accaattgaa agcgtatttc tactccttac ccacaaccac 120 ataccaattt gaggtgttgg acgtgttgta ctccatcctg aggtaggttc tacagaacta 180 gttgtttgta catactctga ttgagtacca gt 212 <210> 792 <211> 212 <212> DNA <213> Artificial Sequence <400> 792 caaattaaat gccacagttt cttctagtaa aatattcatg gtgacctctc ctctttaccc 60 ctcatgtctc tcattaacaa catactcaaa gtcacttgca aatagcggaa tcattagttc 120 tccatcaacg tcacagtgca atagaggtgt acggtattgg tagtcaataa aaatggtgtc 180 tgtttcctta tctacatatg caaaacaacc cg 212 <210> 793 <211> 212 <212> DNA <213> Artificial Sequence <400> 793 ccgtctaaac caaaaatcac agacacacgt gatttccctg taggtagtaa agtaaaagta 60 cgcgccaaag caactaaata ccaaacgggt caaccagtgc caaactttgt aaaaggtaaa 120 acatacacag taaaagaacg taaaacagtt aatcaatctg taagtaaata tgcgtttctt 180 gttgatggta ttaactcatg gttcttagca ca 212 <210> 794 <211> 212 <212> DNA <213> Artificial Sequence <400> 794 agtaacagag acataaggag cttgagtgtc ctgccccact gtcataatac cattttcgtc 60 tgcggtaata cctaaaacag cactctatgc tccacccgct tgtaagtcga aaacattcaa 120 tgatacggtt gtttcacctg tacctttagc agatacgaaa aacggaacgt ttgacgcgta 180 gactgtagta gcctccgctc ctagtccact ga 212 <210> 795 <211> 212 <212> DNA <213> Artificial Sequence <400> 795 actggtactc aatcagagta tgtacaaaca actagttctg tagaacctac ctcaggatgg 60 agtacaacac gtccaacacc tcaatttggt atgtggttgt gggtaaggag tagaaatacg 120 ctttcaaatg gtacgtatac aaattgggta gtaactagct catacacggg tagagactca 180 atttttatta gtgctacagc tccaagtaac cc 212 <210> 796 <211> 212 <212> DNA <213> Artificial Sequence <400> 796 tcaagataac gcagtagaca cgttacagaa ccaagttgac tacatgagta aaatgataaa 60 tagactagca tacaatcaaa gttaggagcg ggaacgaatg ccaatgaatg aggacaactt 120 tatcaaactg caattaacca tggagcgtat tgacgcacgt ttagaggacg tgagagagat 180 taaaaaagag ctgtctggtg cccgtcaaca aa 212 <210> 797 <211> 212 <212> DNA <213> Artificial Sequence <400> 797 cgggttgttt tgcatatgta gataaggaaa cagacaccat ttttattgac taccaatacc 60 gtacacctct attgcactgt gacggtgatg gagaactaat gattccgcta tttgcaagtg 120 actttgatta tgttgttaat gagagacatg aggggtaaag aggagaggtc accatgaata 180 ttttactaga agaaactgtg gcatttaatt tg 212 <210> 798 <211> 212 <212> DNA <213> Artificial Sequence <400> 798 ttgttgacgc gcttgcacga acgttcatga cgcctttagt agtagcctta gcattttcag 60 ttgtccattt aaggactcct gacggtttag agctattacc catgttagat gacgccgtgt 120 ctaggtcgtg tgctaagaac catgagttaa taccatcaac aagaaacgca tatttactta 180 cagattgatt aactgtttta cgttctttta ct 212 <210> 799 <211> 212 <212> DNA <213> Artificial Sequence <400> 799 atggttggac aggaaatggt gcgactatag aatattcaaa cgggaacatg cgagtgttgt 60 ttaacgactc atcaactaac agaagagtct attatagcaa tgacttatta accaactact 120 tgccagctgg agttaaatat tccgtcacaa tagacgcatt cagcaacaat aatgggttaa 180 ttagggtagg taattttgac gctctcagta ca 212 <210> 800 <211> 212 <212> DNA <213> Artificial Sequence <400> 800 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctccagctgg caagtagttg gttaataagt cattgcaata 120 atagactatt ctgatagttg atgagtcgtt aaacaacaca cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc at 212 <210> 801 <211> 212 <212> DNA <213> Artificial Sequence <400> 801 tgcaattaac catggagcgt attgacgcac gtttagagga cgtgagagag attaaaaaag 60 agctgtctgg tgcccgtcaa caaaacgcgg acctagacaa acgtctttcg cagtcaattg 120 accatgttaa caaactagag gacgacatca aagagctaga atcacgtaac acatggctta 180 ctagaacaac cgtaggagca attatcactg gt 212 <210> 802 <211> 212 <212> DNA <213> Artificial Sequence <400> 802 tgtacgtgtc cataggtatt tacctttttc tagagttggg atggttgtac tccatcctga 60 tgtaggttca tcaacgcttg aggtcttgat tgcccactct gttttagttg atttgacaga 120 ggcgccagtt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 180 ttgagtatag ttactatatt gacccatata ta 212 <210> 803 <211> 212 <212> DNA <213> Artificial Sequence <400> 803 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaactggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccgtca caatagacgc attcagcaac aa 212 <210> 804 <211> 212 <212> DNA <213> Artificial Sequence <400> 804 gggttacttg gagctgtagc actaataaaa attgagtctc tacccgtgta tgagctagtt 60 actacccaat ttgtatacgt accaattgaa agcgtatttc tactccttac ccacaaccac 120 ataccaaatt gaggtgttgg acgtgttgta ctccatcctg aggtaggttc tacagaacta 180 gttgtttgta catactctga ttgagtacca gt 212 <210> 805 <211> 212 <212> DNA <213> Artificial Sequence <400> 805 tgtgctaaga accatgagtt aataccatca acaagaaacg catatttact tacagattga 60 ttaactgttt tacgttcttt tactgtgtat gttttacctt ttacaaagtt tggcactggt 120 tgacccggtt ggtatttagt tgctttggcg cgtactttta ctttactacc tacagggaaa 180 tcacgtgtgt ctgtgatttt tggtttagac gg 212 <210> 806 <211> 212 <212> DNA <213> Artificial Sequence <400> 806 cgggttgttt tgcatatgta gataaggaaa cagacaccat ttttattgac taccaatacc 60 gtacacctct attgcactgt gacggtgatg gagaactaat gattccgcta tttgcaagtg 120 actttgagta tgttgttaat gagagacatg aggggtaaag aggagaggtc accatgaata 180 ttttactaga agaaactgtg gcatttaatt tg 212 <210> 807 <211> 211 <212> DNA <213> Artificial Sequence <400> 807 gaaatgtttt tagaccatga gtttgaccta aataaaaaag gtaagcccgt agctaaagga 60 acgtatactg accctaatac tgggtatgtt atggagtttg gcgcgggagg tgtccacgga 120 gctgttgaac agcttattca cattggacgc tttctcatgc gtgactacgg tagtttgtac 180 cctaatgtgt atgtgaattt tgatgttctt t 211 <210> 808 <211> 211 <212> DNA <213> Artificial Sequence <400> 808 tccagatgtg cccacgcggt cacgtacttt attcagagca ataacgtagc caacttgtga 60 tttaaagtta tcaaaagcat agtgacccgc ttgacggtat ttacttgacc cgttcatgct 120 tgcaggaaat gctacgtcaa tagcgtttct tgaaccgtga ctatatgggt ctcctggtct 180 atatccactt gttacgcgca taccagggta t 211 <210> 809 <211> 211 <212> DNA <213> Artificial Sequence <400> 809 gtttatcttt caaactatat tcaattccct cattaacata gtcacgttca aaacggtcat 60 agtagaacca ttcatcaata ccatcaacct gcacgaaaag gctgcctact ccaacaatgg 120 tatatcgatt acctttttcc aatatatctt ctacacataa agtgtctaca catactactc 180 tgtgacctac ctcaaacata ttactcattg c 211 <210> 810 <211> 211 <212> DNA <213> Artificial Sequence <400> 810 agatgtcact aaagtctaca taattatcac tcattttacc acctcattta aaacgtcctc 60 tttagaaacc tccttagcaa tcaaagtatc aaagtctttg ctgtatgttc cacgtgaaac 120 atcctcactg cgatagcgta caccgttgtg taaaatataa tggtctcgct gaatctgttt 180 cttttggtca taccttacaa tgaagttaac a 211 <210> 811 <211> 211 <212> DNA <213> Artificial Sequence <400> 811 ttatatttgg gttaggttcg tcattgaatg agaaacggtc tgttcctgtt tcgttgaaag 60 cgtatgcggt acgtacctcc ccagtggttg gtaaaggtgt agtatgtgta tgcaatactt 120 taccgtttat cttatccatt tcatcaataa caacctcaaa ggtactagaa ccatcatcat 180 caaactcact aacctttggt ataccgtagt t 211 <210> 812 <211> 211 <212> DNA <213> Artificial Sequence <400> 812 agatgtcact aaagtctaca taattatcac tcattttacc acctcattta aaacgtcctc 60 tttagaaacc tccttagcaa tcacagtatc aaagtctttg ctgtatgttc cacgtgaaac 120 atcctcaatg cgatagcgta caccgttgtg taaaatataa tggtctcgct gaatctgttt 180 cttttggtca taccttacaa tgaagttaac a 211 <210> 813 <211> 211 <212> DNA <213> Artificial Sequence <400> 813 gcgtaacgtg taaggttctg taggtcctca ccgaatacag ggatagggct gttttgctca 60 accctactca tagcgtcaac catttcctca aggctaccca aaccctcagc aactagttcg 120 ttagccaatt gagtgtagtt ttctgcgccc tcttgtgaaa gacctaatgc accttgaaac 180 ttattgatgg cgtcttttga ttcattgatt c 211 <210> 814 <211> 211 <212> DNA <213> Artificial Sequence <400> 814 ccccgtactg tgtacgtgaa tttgtccata cggtcttacc cctacttgtg gtaaacctga 60 gcgcatttgt ttttcaattt tcagtgaatc attctccttt ctatctctaa tcattataac 120 acaaaaaagg aggcttaagc ctccttaggt tatgctaaac gcccttgacg tctgttagat 180 accatttgtc cgcgttgctt atctttagtt a 211 <210> 815 <211> 211 <212> DNA <213> Artificial Sequence <400> 815 tgttcgtaaa cctgttgatg gtgctttgac aggcgttgta agggaaggtc ctgaccatgc 60 gtttggtgcg aatgttgtag cccacttagg tttaaacgcc tcagaagggc tgtagtccca 120 tgaacccctg tagaggtttg gtctagcagg gtcgttagac gtatttgggt actgtgatac 180 gtgcccacta ttgacggtga aaccagttgg c 211 <210> 816 <211> 211 <212> DNA <213> Artificial Sequence <400> 816 gtttatcttt caaactatat tcaattccct cattaacata gtcacgttca aaacggtcat 60 agtagaacca ttcatcaata ccaacaacct gcacgaaaag gctgcctact ccaacaatgg 120 tatatcgttt acctttttcc aatatatctt ctacacataa agtgtctaca catactactc 180 tgtgacctac ctcaaacata ttactcattg c 211 <210> 817 <211> 211 <212> DNA <213> Artificial Sequence <400> 817 ccccgtactg tgtacgtgaa tttgtccata cggtcttacc cctacttgtg gtaaacctga 60 gcgcatttgt ttttcaattt tcattgaatc attctccttt ctatctctaa tcattataac 120 acaaaaatgg aggcttaagc ctccttaggt tatgctaaac gcccttgacg tctgttagat 180 accatttgtc cgcgttgctt atctttagtt a 211 <210> 818 <211> 211 <212> DNA <213> Artificial Sequence <400> 818 tacctatgat tatgtatata ctagcgtgtg tttttatggc tattggtgcc tttttggtag 60 atataaccgt aggttttatg gtagtaggtg gcgcttgttt ggctacaagt tttaagctat 120 caaaggaatt agagcaggtt gataacatca acgataaagg agagagtcac taatgggaat 180 ttttatcaga aacaagccac acgaagagcg g 211 <210> 819 <211> 211 <212> DNA <213> Artificial Sequence <400> 819 tgttcgtaaa cctgttgatg gtgctttgac aggcgttgta agggaaggtc ctgaccatgc 60 gtttggtgcg aatgttgtag ccctcttagg tttaaacgcc tcagaagggc tgtagtccca 120 tgaacccatg tagaggtttg gtctagcagg gtcgttagac gtatttgggt actgtgatac 180 gtgcccacta ttgacggtga aaccagttgg c 211 <210> 820 <211> 211 <212> DNA <213> Artificial Sequence <400> 820 gaaatgtttt tagaccatga gtttgaccta aataaaaaag gtaagcccgt agctaaagga 60 acgtatactg accctaatac tggttatgtt atggagtttg gcgcgggagg tgtccacgga 120 gctgttgtac agcttattca cattggacgc tttctcatgc gtgactacgg tagtttgtac 180 cctaatgtgt atgtgaattt tgatgttctt t 211 <210> 821 <211> 211 <212> DNA <213> Artificial Sequence <400> 821 aatgtgtaca ataataacaa aatataacct actacccaac acaacaaccc tacatggttt 60 catgatagac taatgtggag gaggtaatat aatgttaata ccaacggaac aacagcaaat 120 ggtcatatac aaatgggaaa cacataatct aaatcatagt gaggttggct caggcaagac 180 actcatggca ttagaatcgt ttaaaaaatc a 211 <210> 822 <211> 211 <212> DNA <213> Artificial Sequence <400> 822 tctagaagct ctcctctgag ctttggagac ccacttaggg taattatacc taaaccttgt 60 ttagacccct cagaagccca atcagacacc ttagacgcaa ggcacactac tacgagtttc 120 tttagccatg attttttaaa cgattctaat gccatgagtg tcttgcctga gccaacctca 180 ctatgattta gattatgtgt ttcccatttg t 211 <210> 823 <211> 211 <212> DNA <213> Artificial Sequence <400> 823 ttcacgtaca cagtacgggg aattcatcat ctacagcgca aaacgaggca gactatcata 60 tgcgcagacc cgtcaacagt gggttcttct cgcacgtagt aggtaacggg cgagtaattc 120 aaacagctcg cacaaacgcg ggcttttatg acgtaggtgg cggatggaac tcgtggggat 180 atgcggcaat tgaattgatt gaatcgcaca a 211 <210> 824 <211> 211 <212> DNA <213> Artificial Sequence <400> 824 ggcgtttatt gagacaaaca atttagacgt acaaggtatt tgttatgacc ctgcacagtc 60 tcaattaatt accacaagac tagcagacgg gtatgaggac gtactctttg atgtacgtca 120 gtcttatctg cgattaaacc cacctactaa acaattacaa gtggatatac gagcgggcaa 180 ggtccttcac tttaacaacc ctctattgac a 211 <210> 825 <211> 211 <212> DNA <213> Artificial Sequence <400> 825 aaggttgaac atgttagatt aacagaatat aatgacgcct atatgagtgt actgttgttt 60 aggcagaaag tacgtagata ttatttaact gtaaacggta aggagtcaag agagtataaa 120 taccactagt ggtttttgca aaaagtacca ctattgtata aaattagtag gtatgtaaat 180 actcgtatag caataaaacg cattgaaaac a 211 <210> 826 <211> 211 <212> DNA <213> Artificial Sequence <400> 826 actatgcttt tgataacttt aaatcacaag ttggctacgt tattgctctg aataaagtac 60 gtgaccgcgt gggcacatct ggaccgggta ttcatgacac atggactaat tgggcgtcag 120 gtggacacat ggaccactta cacattaatg gtgtgaaaga ccctcagtca caaggtggag 180 caattgacac cacagcaaca gggtcagggg t 211 <210> 827 <211> 211 <212> DNA <213> Artificial Sequence <400> 827 ttgacccaga tgggcgtttt aaacttgaga atggggttat gattgacacg caagaagctc 60 ctaaatggtc cagactctta tcatcaacag gaggtttgtt cacacgtgct gtaacgtatg 120 acacccttga taaaggtaaa ttggcttcac ttgctgttag tgaattgaaa aagaaaagtc 180 aacctgcttt taattatgaa gtaaacgtag t 211 <210> 828 <211> 211 <212> DNA <213> Artificial Sequence <400> 828 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttcttgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg ctagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgtccaacc a 211 <210> 829 <211> 211 <212> DNA <213> Artificial Sequence <400> 829 ccccgtactg tgtacgtgaa tttgtccata cggtcttacc cctacttgtg gtaaacctga 60 gcgcatttgt ttttcaattt tcagtgaatc attctccttt ctatctctaa tcattataac 120 acaaaaatgg aggcttaagc ctccttaggt tatgctaaac gcccttgacg tctgttagat 180 accatttgtc cgcgttgctt atctttagtt a 211 <210> 830 <211> 211 <212> DNA <213> Artificial Sequence <400> 830 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccagtaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaatgga ttttgaccat c 211 <210> 831 <211> 211 <212> DNA <213> Artificial Sequence <400> 831 ttgacccaga tgggcgtttt aaacttgaga atggggttat gattgacacg caagaagctc 60 ctaaatggtc cagactctta tcatcaacag gaggtttgtt cacacgtgct gtaacgtatg 120 acaccctgga taaaggtaaa ttggcttcac ttgctgttag tgaattgaaa aagaaaagtc 180 aacctgcttt taattatgaa gtaaacgtag t 211 <210> 832 <211> 211 <212> DNA <213> Artificial Sequence <400> 832 aaagaacatc aaaattcaca tacacattag ggtacaaact accgtagtca cgcatgagaa 60 agcgtccaat gtgaataagc tgtacaacag ctccgtggac acctcccgcg ccaaactcca 120 taacataccc agtattaggg tcagtatacg ttcctttagc tacgggctta ccttttttat 180 ttaggtcaaa ctcatggtct aaaaacattt c 211 <210> 833 <211> 211 <212> DNA <213> Artificial Sequence <400> 833 ccgctcttcg tgtggcttgt ttctgataaa aattcccatt agtgactctc tcctttatcg 60 ttgatgttat caacctgctc taagtccttt gatagcttaa aacttgtagc caaacaagcg 120 ccacctacta ccataaaacc tacggttata tctaccaaaa aggcaccaat agccataaaa 180 acacacgcta gtatatacat aatcataggt a 211 <210> 834 <211> 211 <212> DNA <213> Artificial Sequence <400> 834 gcgtaacgtg taaggttctg taggtcctca ccgaatacag ggatagggct gttttgctca 60 accctactca tagcgtcaac catgtcctca aggctaccca aaccctcagc aactagttcg 120 ttagccaatt gagtgtagtt ttctgcgccc tcttgtgaaa gacctaatgc accttgaaac 180 ttattgatgg cgtcttttga ttcattgatt c 211 <210> 835 <211> 211 <212> DNA <213> Artificial Sequence <400> 835 tgttaacttc attgtaaggt atgaccaaaa gaaacagatt cagcgagacc attatatttt 60 acacaacggt gtacgctatc gcagtgagga tgtttcacgt ggaacataca gcaaagactt 120 tgatactgtg attgctaagg aggtttctaa agaggacgtt ttaaatgagg tggtaaaatg 180 agtgataatt atgtagactt tagtgacatc t 211 <210> 836 <211> 211 <212> DNA <213> Artificial Sequence <400> 836 gcaatgagta atatgtttga ggtaggtcac agagtagtat gtgtagacac tttatgtgta 60 gaagatatat tggaaaaagg taatcgatat accattgttg gagtaggcag ccttttcgtg 120 caggttgttg gtattgatga atggttctac tatgaccgtt ttgaacgtga ctatgttaat 180 gagggaattg aatatagttt gaaagataaa c 211 <210> 837 <211> 211 <212> DNA <213> Artificial Sequence <400> 837 tgttcgtaaa cctgttgatg gtgctttgac aggcgttgta agggaaggtc ctgaccatgc 60 gtttggtgcg aatgttgtag ccctcttagg tttaaacgcc tcagaagggc tgtagtccca 120 tgaacccctg tagaggtttg gtctagcagg gtcgttagac gtatttgggt actgtgatac 180 gtgcccacta ttgacggtga aaccagttgg c 211 <210> 838 <211> 210 <212> DNA <213> Artificial Sequence <400> 838 gtctcacgga gtttcaggcg tctcattggg ttaccttttt tagattgtgt ttcaatgttc 60 tctgtaacaa caacctcttt tagtccccct gtcatggggt cataactcat ggcgttacct 120 tctaatgttt tccaaagttc aaacatggta cgcgcgttct ctttttgttg cttagttggt 180 gtgaaaatag tgttcattaa tttcatcccc 210 <210> 839 <211> 210 <212> DNA <213> Artificial Sequence <400> 839 tgctgtttga attactcgcc cgttacctac tacgtgcgag aagaacccac tgttgacggg 60 tctgcgcata tgatagtctg cctcgttttg cgctgtagat gatgaattcc ccgtactgtg 120 tacgtgactt tgtccatacg gtcttacccc tacttgtggt aaacctgagc gcatttgttt 180 ttcaattttc attgaatcat tctcctttct 210 <210> 840 <211> 210 <212> DNA <213> Artificial Sequence <400> 840 tggtttttgc aaaaagtacc actattgtat aaaattagta ggtatgtaaa tactcgtata 60 gcaataaaac gcattgaaaa caggggggga gaacgaaatg ggctacttta agaatttgtt 120 attagcgttg ggttatattg ttgctttgtt taccataatt aagttgggtg cagttggttt 180 tggctattta atgacattag tgagccattt 210 <210> 841 <211> 210 <212> DNA <213> Artificial Sequence <400> 841 aaatggatca ctaatgtcat taaatagcca aaaccaactg cacccaaatt aattatggta 60 aacaaagcaa cattataaaa caccgatatt aacaaattct taaagtagca catttcgttc 120 tccccccatg ttttcaatgc gttttattgc tttacgagta tttacatacc tactaatttt 180 atacaatagt ggtacttttt gcaaaaacca 210 <210> 842 <211> 210 <212> DNA <213> Artificial Sequence <400> 842 tcccgtttcc tttacagcct ccttttcttt cagttcaaat tttgactcaa tatattcctc 60 atggtcaaaa ataaaataca tagtatgcat atctgtcaaa acatatagtt gaccgtctcc 120 gttgaacacg gggtactctt tgccaaacct ccaatttaca ctattaaact cacctgtgta 180 aattaaaaca tctccgactt ttagttcatt 210 <210> 843 <211> 210 <212> DNA <213> Artificial Sequence <400> 843 gcggaactaa accctgcttt aactaaagat aagcaacgcg gacaaatggt atctaacaga 60 cgtcaagggc gtttagcata acctaaggag gcttaagcct ccttttttgt gttataatga 120 ttagagagag aaaggagaat gattcaatga aaattgaaaa acaaatgcgc tcaggtttac 180 cacaagtagg ggtaagaccg tatggacaaa 210 <210> 844 <211> 210 <212> DNA <213> Artificial Sequence <400> 844 gtctcacgga gtttcaggcg tctcattggg ttaccttttt tagattgtgt ttcaatgttc 60 tctgtaacaa caacctcttt tattccccct gtcatggggt cataactcat ggcgttacct 120 tctaatgatt tccaaagttc aaacatggta cgcgcgttct ctttttgttg cttagttggt 180 gtgaaaatag tgttcattaa tttcatcccc 210 <210> 845 <211> 210 <212> DNA <213> Artificial Sequence <400> 845 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa 60 taagtcattg ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat 120 gttcccgatt gaatattcta tagtcgcacc atttcctgtc caaccattaa tagtggggtc 180 tttcgagaaa tcataattca atactaaatt 210 <210> 846 <211> 210 <212> DNA <213> Artificial Sequence <400> 846 atcaccgttg ttttttacat atatactatg cgtgtagttt tgtcctatga tgtactgtgt 60 tcctttaatt tctaacacac ctctgagatt attacttgtg ttcttagtta ccttataatt 120 gacagcatta ctagcacccc attctggtac agaaacccct gttgttcgtg taaattcact 180 agttccgtca gacactagtg ttggttgttc 210 <210> 847 <211> 210 <212> DNA <213> Artificial Sequence <400> 847 ttctcattta actcacgcgc cttttcaacc actaaatcac ctaattttgt agtatctaaa 60 ttcatgtcta ttttcctccc ttctttggtt gaaacaacca tttagaaaac attagtgaca 120 accctataac taatggcgtt aggtatgcaa tcaattttct gagtcctccc acgctttaat 180 gaacccctca atttctttga catccccatc 210 <210> 848 <211> 210 <212> DNA <213> Artificial Sequence <400> 848 aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct ttcgagaaat 60 cataattcaa tactaaatta tcatttgggt attggagtgt gaacctctct tttccatcac 120 tactccaagc gtaagctgtg tgtaaaaatg gattttgacc atcctgtacg tttgcaatac 180 tcaatggctt tgactctaat gccatgtttt 210 <210> 849 <211> 210 <212> DNA <213> Artificial Sequence <400> 849 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa 60 taagtcattg ctataataga ctcttctgtt agttgatgag tcgttaaaca acactcgcat 120 gttcccgatt gaatattcta tagtcgcacc atttcctgtc caaccattaa tagtggggtc 180 tttcgagaaa tcataattca atactaaatt 210 <210> 850 <211> 210 <212> DNA <213> Artificial Sequence <400> 850 tacgagggaa ttagggacca tgttaccatg ttacagagca acacagactg tcacgcctac 60 attcctcatg atgaggaggc tgtacgtatt acagacgcgt tctgtgatga catttctgag 120 cgcgtaggta ttgtattgga caaagatgag ttcattgcct tataccagaa agatgtcaac 180 aattatattg gtattgacgc taaaggtaaa 210 <210> 851 <211> 210 <212> DNA <213> Artificial Sequence <400> 851 tggttcctat agacatttgt cagttcgcca aaatacagag ttcgccacta aatacttgtc 60 agagggtggt acgagtattc atgtacacca gagtggtagt tattactcat atgagaacct 120 caaggcgcag aatgggctag acgaaagaca tgataaggag tttatacaat actgcaaaga 180 aagaggttat gattatgtat aagtacgtag 210 <210> 852 <211> 210 <212> DNA <213> Artificial Sequence <400> 852 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa 60 taagtcattg ctataataga ctcttctgtt agttgatgag tcgttaaaca acactcgcat 120 gttcccggtt gaatattcta tagtcgcacc atttcctgtc caaccattaa tagtggggtc 180 tttcgagaaa tcataattca atactaaatt 210 <210> 853 <211> 210 <212> DNA <213> Artificial Sequence <400> 853 gcgtaagctg tgtgtaaaaa tggattttga ccatcctgta cgtttgcaat actcaatggc 60 tttgactcta atgccatgtt ttgtacctcc tctaataatc tacagaacaa taatatgtat 120 atacatttga ttgtcctgca tttactgtga ttgtttttcc tgttcctgtc catgaggtgt 180 ctaatacgtt tgaggcgtca tatctacgcc 210 <210> 854 <211> 210 <212> DNA <213> Artificial Sequence <400> 854 ttcagtgagt accttgataa aacaggtaag aaaattgatt tgttactcct agaggctaac 60 tatgacggtg ctgtaattgg ttatagtgaa tatatgaaaa ttcacagcgg ttatgatacg 120 tataatactg gttcctatag acatttgtca gttcgccaaa atacagagtt cgccactaaa 180 tacttgtcag agggtggtac gagtattcat 210 <210> 855 <211> 210 <212> DNA <213> Artificial Sequence <400> 855 tagtaaatgg ggtaaaattg cctattaata cattgtttgg tgccacaggt gcagagttta 60 atgggttata tgacccacgt tttcaatttc taacatgtgt gattgggcaa ttaattatgg 120 ctgacttata cgagggaatt agggaccatg ttaccatgtt acagagcaac acagactgtc 180 acgcctacat tcctcatgat gaggaggctg 210 <210> 856 <211> 210 <212> DNA <213> Artificial Sequence <400> 856 tggtttttgc aaaaagtacc actattgtat aaaattagta ggtatgtaaa tactcgtata 60 gcaataaaac gcattgaaaa caggggggga gaacgaaatg ggctacttta agaatttgtt 120 attagcggtg ggttatattg ttgctttgtt taccataatt aagttgggtg cagttggttt 180 tggctattta atgacattag tgagccattt 210 <210> 857 <211> 210 <212> DNA <213> Artificial Sequence <400> 857 tcagagtaga aattaaaccc catatctgtt gaacccatgg tgtaagttgg ttcaaagcta 60 atgtacttac tctcattggg atatattgtt ttacccactc ccattctgtt tgaaatagaa 120 ataggttgat caccgttgtt ttttacatat atactatgcg tgtagttttg tcctatgatg 180 tactgtgttc ctttaatttc taacacacct 210 <210> 858 <211> 210 <212> DNA <213> Artificial Sequence <400> 858 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa 60 taagtcattg ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat 120 gttcccggtt gaatattcta tagtcgcacc atttcctgtc caaccattaa tagtggggtc 180 tttcgagaaa tcataattca atactaaatt 210 <210> 859 <211> 210 <212> DNA <213> Artificial Sequence <400> 859 gtctcacgga gtttcaggcg tctcattggg ttaccttttt tagattgtgt ttcaatgttc 60 tctgtaacaa caacctcttt tagtccccct gtcatggggt cataactcat ggcgttacct 120 tctaatgatt tccaaagttc aaacatggta cgcgcgttct ctttttgttg cttagttggt 180 gtgaaaatag tgttcattaa tttcatcccc 210 <210> 860 <211> 209 <212> DNA <213> Artificial Sequence <400> 860 caaggttacc taaatcattt ttagcaatct taacaataac aaactcatcc tcaacttcat 60 cctgttcccc atccacgcgt agagtcactt tcttttctat ttcttgctcc tgtaaacgca 120 ttccctcagc gcgtactttc tcatattgct gtactgcctc cattaggtct aaaccgttgt 180 ttgcatatac agcttgaata gaggttcgt 209 <210> 861 <211> 209 <212> DNA <213> Artificial Sequence <400> 861 caaggttacc taaatcattt ttagcaatct taacaataac aaactcatcc tcaacttcat 60 cctgttcccc atccacgcgt atagtcactt tcttttctat ttcttgctcc tgtaaacgca 120 ttccctccgc gcgtactttc tcatattgct gtactgcctc cattaggtct aaaccgttgt 180 ttgcatatac agctagaata gaggttcgt 209 <210> 862 <211> 209 <212> DNA <213> Artificial Sequence <400> 862 tcccgtttcc tttacagcct ccttttcttt cagttcaaat tttgactcaa tatattcctc 60 atggtcaaaa ataaaataca tcttatgcat atctgtcaaa acatatagtt gaccgtctcc 120 gttgaacacg gggtactctt tgccaaacct ccaatttaca ctattaaact cacctgtgta 180 aattaaaaca tctccgactt ttagttcat 209 <210> 863 <211> 209 <212> DNA <213> Artificial Sequence <400> 863 ttgctgaatg cgtctattgt gacggaatat ttaactcctg ctggcaagta gttggttaat 60 aagtcattgc tataatagac tcttctgtta gttgatgagt cgttaaacaa cactcgcatg 120 ttcccgtgtg aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct 180 ttcgagaaat cataattcaa tactaaatt 209 <210> 864 <211> 209 <212> DNA <213> Artificial Sequence <400> 864 gtgtaagcca atgcctccaa acaacaaagc aataataaca tatagtccta aacttggttt 60 attcattcta gtagtcctcc aataatgttt gtatgaaatc gtttaactcg tccacgtagt 120 cgtatagaga atcaaggtca tcaattaatt tatcattttt ctcaatgagt tcatcaactt 180 ccttatctaa aaattcaacc tgaccacgt 209 <210> 865 <211> 209 <212> DNA <213> Artificial Sequence <400> 865 ctctaaacga gcgtctaaca acttttccct tagcatttcg ttttctctaa tgaggttatt 60 acgttcacga agtaatagaa ctttatcctc tttatcaagg ttctcaggcg tttcccatct 120 attggacctt aggttcactc tccttataag tgaaatcact tgcgaaaaat gaagcgtaac 180 gtttatcatt aatgtctgta gggaatacc 209 <210> 866 <211> 209 <212> DNA <213> Artificial Sequence <400> 866 ctctaaacga gcgtctaaca acttttccct tagcatttcg ttttctctaa tgaggttatt 60 acgttcacga agtaatagaa cgttatcctc tttatcaagg ttctcaggcg tttcccatct 120 attggacatt aggttcactc tccttataag tgaaatcact tgcgaaaaat gaagcgtaac 180 gtttatcatt aatgtctgta gggaatacc 209 <210> 867 <211> 209 <212> DNA <213> Artificial Sequence <400> 867 cgttgttata ctagctcata cgcaacatca aggttaccta aatcattttt agccatctta 60 acaataacat actcatcctc acctacatcc tgttccccat ccacgcgtaa agtcactttc 120 ttttctattt cttgctcctg taaacgcatt ccctcagcgc gtacattctc atattgctgt 180 actgcctcca ttaggtctaa accgttgtt 209 <210> 868 <211> 209 <212> DNA <213> Artificial Sequence <400> 868 tatgaaaata agtgtctgcg cgttgttagt gctgtaataa tgtcaatcca tgaaataacc 60 actggtacac ccgtccaaaa taagaatagg aacaagaaac ctgagccaag ttttccctca 120 tacatactgt gtaagccaat gcctccaaac aacaaagcaa taataacata tagtcctaaa 180 cttggtttat tcattctagt agtcctcca 209 <210> 869 <211> 209 <212> DNA <213> Artificial Sequence <400> 869 cgttgttata ctagctcata cgcaacatca aggttaccta aatcattttt agcaatctta 60 acaataacaa actcatcctc accttcatcc tgttccccat ccacgcgtat agtcactttc 120 ttttctagtt cttgctcctg taaacgcatt ccctcagcgc gtactttctc atattgctgt 180 actgcctcca ttaggtctaa accgttgtt 209 <210> 870 <211> 209 <212> DNA <213> Artificial Sequence <400> 870 ggtattccct acagacatta atgataaacg ttacgcttca tttttcgcaa gtgatttcac 60 ttataaggag agtgaaccta aggtccaata gatgggaaac gcctgagaac cttgataaag 120 aggataacgt tctattactt cgtgaacgta ataacctcat tagagaaaac gaaatgctaa 180 gggaaaagtt gttagacgct cgtttagag 209 <210> 871 <211> 209 <212> DNA <213> Artificial Sequence <400> 871 acgaacctct attctagctg tatatgcaaa caacggttta gacctaatgg aggcagtaca 60 gcaatatgag aaagtacgcg cggagggaat gcgtttacag gagcaagaaa tagaaaagaa 120 agtgactcta cgcgtggatg gggaacagga tgaagttgag gatgagtttg ttattgttaa 180 gattgctaaa aatgatttag gtaaccttg 209 <210> 872 <211> 208 <212> DNA <213> Artificial Sequence <400> 872 ttgaggggtc tgctattagt gactcacgtg gatatgtata cgcctctggt gtgaagtctg 60 agacgttgac gcttgagaaa gtccaagact ttgtagcaaa caaaacaacg ccagttggac 120 agtaaagagg ggtaataccc ctcttttttt gtgcgctata tgatataata ttaatagaac 180 ataacatatt aggaggaatt ataatgat 208 <210> 873 <211> 208 <212> DNA <213> Artificial Sequence <400> 873 ttgttagttt gtcaagtgta ttacctagtt cagcggttcc gtcaatacct aaaccaaact 60 tcatatttcc tactggtttt ccgctttgca ccatgtgtta atcagctcct tttttctcta 120 gcttttctag ttcctcagga cttaagaaac gcttaataaa gtcagcgcca tccatcacct 180 tttcttgttt agactcttta ccaaacaa 208 <210> 874 <211> 208 <212> DNA <213> Artificial Sequence <400> 874 aaaaagtaga tgaggaaaaa cttgctttca acattattat ggcaagcgct ttaggtgcta 60 aactcgtaga tgagtatggg attgatagag acacgatttc agaccgtatt gacgatgtat 120 taggataaag ggaggaaaac aaaatgagta aagtatttga ggataatttt actaaacccc 180 taccagtggg gacgaaggtg cgcttgat 208 <210> 875 <211> 208 <212> DNA <213> Artificial Sequence <400> 875 tttctcaagc gtcaacgtct cagacttcac accagaggcg tatacatatc cacgtgagtc 60 actaatagca gacccctcaa gagtatcagt attagggtca gtgcctccac cctctgaggt 120 attcaacgca acgtcagggt gagcaaagcg aactttagtc agtcccatat atacctcatt 180 accatctgcg tcatctgata caaaagta 208 <210> 876 <211> 208 <212> DNA <213> Artificial Sequence <400> 876 attaacaagg tattaaacgg taatgggttt gatgatgagt taaatatgct gtttaacaga 60 gttctagagg aggagttcca tggcaacgcg ttagccatgg acgacctcat ttatgaacta 120 aacggatcta gcactcaaga taacgcagta gacacgttac agaaccaagt tgactacatg 180 agtaaaatga taaatagact agcataca 208 <210> 877 <211> 208 <212> DNA <213> Artificial Sequence <400> 877 taacaggact tgaggaaaaa acctttgagg aacagttaga aacccttgag gaaacatatt 60 catccctctt agaaagtagc tggcaactct cagagataga gaacgctgac tactttcttt 120 tattacactt gtttggtaaa gagtctaaac aagaaaaggt gatggatggc gctgacttta 180 ttaagcgttt cttaagtcct gaggaact 208 <210> 878 <211> 208 <212> DNA <213> Artificial Sequence <400> 878 atcaagcgca ccttcgtccc cactggtagg ggtttagtaa aattatcctc aaatacttta 60 ctcattttgt tttcctccct gtatcctaat acatcgtcaa tacggtctga aatcgtgtct 120 ctatcaaacc catactcatc tacgagttta gcacctaaag cgcttgccat aataatgttg 180 aaagcaagtt tttcctcatc tacttttt 208 <210> 879 <211> 208 <212> DNA <213> Artificial Sequence <400> 879 gaactttgag catatccaat caaacaacgg aattaaacca gttacaaaaa acccatttac 60 ctacaatgca cctgtagcaa acaaagcttc cgttgttaaa acatctagat ggctactcaa 120 gtataaatac tcagtagcca caagggaggt agtggataag gtaacatgga caatgaaatc 180 taaggaagtc ctacacattc gtgcaggt 208 <210> 880 <211> 208 <212> DNA <213> Artificial Sequence <400> 880 gtcaatgatg gacgtggtgc tgaaatggtt attgacccaa gtggtcaagc ggttatccct 60 aaaggtaaga acgtaacgat gtggggacga aaaggaaccc acgttttaac agcagaagaa 120 actgcaccag tgttaggtca taaacgtcct aagtttgcat acaaaaaagg tactggcttc 180 tttgacaaaa ttacaggagg cgtaaaaa 208 <210> 881 <211> 208 <212> DNA <213> Artificial Sequence <400> 881 ggcaccagac agctcttttt taatctctct cacgtcctct aaacgtgcgt caatacgctc 60 catggttaat tgcattttga taaagttgtc ctcattcatt ggcattcgtt cccgctccta 120 actttgagtg tatgctagtc tatttatcat tttactcatg tagtcaactt ggttctgtaa 180 cgtgtctact gcgttatctt gagtgcta 208 <210> 882 <211> 208 <212> DNA <213> Artificial Sequence <400> 882 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca ccaataatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagggtat 180 aaccgcaggg gcaactcatg cttttagt 208 <210> 883 <211> 208 <212> DNA <213> Artificial Sequence <400> 883 tactacgcta gagaatactt tttcaactaa tttgcttggg ttagttgcgt agtcccaaac 60 gtcaccaaca acactgctaa ccttatcaaa cgcactttta gccatgtttt tggcaccgtt 120 ccagatgatt tttacgcctc ctgtaatttt gtcaaagaag ccagtacctt ttttgtatgc 180 aaacttagga cgtttatgac ctaacact 208 <210> 884 <211> 208 <212> DNA <213> Artificial Sequence <400> 884 acctgcacga atgtgtagga cttccttaga tttcattgtc catgttacct tatccactac 60 ctcccttgtg gctactgagt ctttatactt gagtagccat ctagatgttt taacaacgga 120 agctttgatt gctacaggtg cattgtaggt aaatgggttt tttgtaactg gtttaattcc 180 gttgtttgat tggatatgct caaagttc 208 <210> 885 <211> 208 <212> DNA <213> Artificial Sequence <400> 885 ttgtggtaat taattgagac tgtgcagggt cataacaaat accttgtacg tctaaattgt 60 ttgtctcaat aaacgccaaa tcccaattta acatatcctc ccaatcacac tgaccgtcag 120 gacgggacga aatttcacaa tacccctgtt tggaatattg tctatagggt gttctatcgt 180 tagcctcttt ctgaacaata ccaccacc 208 <210> 886 <211> 208 <212> DNA <213> Artificial Sequence <400> 886 acctgcacga atgtgtagga cttccttaga tttcattgtc catgttacct tatccactac 60 ctcccttgtg gctactgagt atttatactt gagtagccat ctagatgttt taacaacgga 120 agctttgatt gctacaggtg cattgtaggt aaatgggttt tttgtaactg gtttaattcc 180 gttgtttgat tggatatgct caaagttc 208 <210> 887 <211> 208 <212> DNA <213> Artificial Sequence <400> 887 aaaaagtaga tgaggaaaaa cttgctttca acattattat ggcaagcgct ttaggtgcta 60 aactcgtaga tgagtatggg attgatagag acacgatttc agaccgtatt gacgatgtat 120 taggatacag ggaggaaaac aaaatgagta aagtatttga ggataatttt actaaacccc 180 taccagtggg gacgaaggtg cgcttgat 208 <210> 888 <211> 207 <212> DNA <213> Artificial Sequence <400> 888 accaatttaa ggggtttcct ctcaaagcgc gtactaaaat tcccgcgata aaagagtggc 60 aagctcaaga gagttacaaa acattaggta aaataagaaa catgaataaa ggggtcttat 120 gtggggacca aaacaaatta ttagtagtag actgtgacgt aaaaggtaaa gcaaacggaa 180 tacactcttt tactacctta atgaaag 207 <210> 889 <211> 207 <212> DNA <213> Artificial Sequence <400> 889 atagtaccac ggacactgta cctgaggaca ctgcgccaaa tatcctatta aacggttcac 60 aggacaatag tatacagtag tggggaatct ttgacgcagt aacggctaca ccaacagcag 120 gagccactaa attaactaaa acagcagtgt caacaatacg tcctgcatac ctatcaaatg 180 gctacagtgc tttgcgcggt acaacgt 207 <210> 890 <211> 207 <212> DNA <213> Artificial Sequence <400> 890 tacatttatt agtttatcaa aaccccaacc agttgtcaag cattattttt aaatttcttg 60 taaatgttcg tacggaatga gctgacgtat accatcaatc gttctacatg gtatagggtc 120 tctgtgtgtc tctttctcaa ttaatacttt ctctgtaggt gtcaattcgt tttcaggtag 180 ttcgtacaag actgccccaa ttggtaa 207 <210> 891 <211> 207 <212> DNA <213> Artificial Sequence <400> 891 ttctaagtca agcaatgcct cacgtccaat gagtaactcc tccttaccta caggcggttc 60 tactgtacct gtaacaatac caggtgtcac ttttgctttt cgccatttat taatcgttac 120 agtaatcatt tatttttcct ccttattaga cattattccc ataggaacat atcatttctt 180 ataacaaaaa tatcttctga cttagta 207 <210> 892 <211> 207 <212> DNA <213> Artificial Sequence <400> 892 gctagaaact gataagccac aggctaatat ggtgaatgaa gaactgacag atacagcacg 60 ttattcaacc aattcaggta aacaattgtt tgacgtctta gcagatgacc tactaacaga 120 tgaccaagat gagggtttct taattggtaa catttataag tacattaaac gccacaaaga 180 aaaaggtggc attactgacc ttgaaaa 207 <210> 893 <211> 207 <212> DNA <213> Artificial Sequence <400> 893 acgttgtacc gcgcaaagca ctgtagccat ttgataggta tgcaggacgt attgttgaca 60 ctgctgtttt agttaatttc gtggctcctg ctgttggtgt agccgttact gcgtcaaaga 120 ttccccaata ctgtatacta ttgtcctgtg aaccgtttaa taggatattt ggcgcagtgt 180 cctcaggtac agtgtccgtg gtactat 207 <210> 894 <211> 207 <212> DNA <213> Artificial Sequence <400> 894 gtcaaacgtt ccgtttttcg tatctgctaa aggtacaggt gaaacaaccg tatcattgaa 60 tgttttcgac ttacaagcgg gtggagcata tagtgctgtt ttaggtatta ccgcagacga 120 aaatggtctt atgacagtgg ggcaggacac tcaagctcct tatgtctctg ttacttttgt 180 atcagatgac gcagatggta atgaggt 207 <210> 895 <211> 207 <212> DNA <213> Artificial Sequence <400> 895 tattgttaca ggtacagtag aaccgcctgt aggtaaggag gagttactca ttggacgtga 60 ggcattgctt gacttagaat cagatagcat ttacattgag gctagtgatt taacttgggt 120 attccctaca gacattaatg ataaacgtta cgcttcattt ttcgcaagtg atttcactta 180 taaggagagt gaacctaatg tccaata 207 <210> 896 <211> 207 <212> DNA <213> Artificial Sequence <400> 896 tctctttctc aattaatact ttctctgtag gtgtcaattc gttttcaggt agttcgtaca 60 agactgcccc aattggtaat ggtgtcgtct cgttgtttac taactcatat gttttcaaac 120 taattcctcc tctagtttat caattatatt ctcaacttca tttaataagt cctcgttatc 180 aacattttgc tgtactacgt taagcgc 207 <210> 897 <211> 207 <212> DNA <213> Artificial Sequence <400> 897 ttatgacagt ggggcaggac actcaagctc cttatgtctc tgttactttt gtatcagatg 60 acgcagatgg taatgaggtc tatatgggac tgactaaagt tcgctttgct caccctgacg 120 ttgcgttgaa tacctcagag ggtggaggca ctgaccctaa tactgatact attgaggggt 180 ctgctattag tgactcacgt ggatatg 207 <210> 898 <211> 207 <212> DNA <213> Artificial Sequence <400> 898 gctagaaact gataagccac aggctaatat ggtgaatgaa gaactgacag atacagcacg 60 ttattcaacc aattcaggtc aacaattgtt tgacgtctta gcagatgacc tactaacaga 120 tgaccaatat gagggtttct taattggtaa catttataag tacattaaac gccacaaaga 180 aaaaggtggc agtactgacc ttgaaaa 207 <210> 899 <211> 207 <212> DNA <213> Artificial Sequence <400> 899 tggacaggaa atggtgcgac tatagaatat tcaaacggga acatgcgagt gttgtttaac 60 gactcatcaa ctaacagaat agtctattat agcaatgact tattaaccaa ctacttgcca 120 gcaggaggta aatattccgt cacaatagac gcattcagca acaataatgg gttaattagg 180 gtaggtaatt ttgacgctct cagtaca 207 <210> 900 <211> 207 <212> DNA <213> Artificial Sequence <400> 900 tggacaggaa atggtgcgac tatagaatat tcaaacggga acatgcgagt gttgtttaac 60 gactcatcaa ctaacagaag agtctattat agcaatgact tattaaacaa ctacttgcca 120 gcaggagata aatattccgt cacaatagac gcattcagca acaataaagg gttaaatagg 180 gtagctaata tagacgctct cagtaca 207 <210> 901 <211> 207 <212> DNA <213> Artificial Sequence <400> 901 tctattttca taccagtggg caattagaaa cattgtagca atatcaaagc gtgggtccgt 60 tggttggtcc tttacctcaa tggctcccat caaaaaagaa actgctgttt cttgtaacat 120 tgttaaagac tcgtcatcca tattatggtc aatgcgtaga ttatttttaa tttggtcaat 180 tgttagcatt atctcactcc tatctaa 207 <210> 902 <211> 207 <212> DNA <213> Artificial Sequence <400> 902 acgttgtacc gcgcaaagca ctgtagccat ttgataggta tgcaggacgt attgttgaca 60 ctgctgtttt agttaatttc gtggctcctg ctgttggtgt agccgttact gcgtcaaaga 120 ttccccacta ctgtatacta ttgtcctgtg aaccgtttaa taggatattt ggcgcagtgt 180 cctcaggtac agtgtccgtg gtactat 207 <210> 903 <211> 207 <212> DNA <213> Artificial Sequence <400> 903 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagct acaataatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgagtgtat 180 aaccgcaggg gcaactaatg cttttag 207 <210> 904 <211> 207 <212> DNA <213> Artificial Sequence <400> 904 tctattttca taccagtggg caattagaaa cattgtagca atatcaaagc gtgggtccgt 60 tggttggtcc tttacctcac tggctcccat caaaaaagaa actgctgttt cttgtaacat 120 tgttaaagac tcgtcatcca tattatggtc aatgcgtaga ttatttttaa tttggtcaat 180 tgttagcatt atctcactcc tatctaa 207 <210> 905 <211> 207 <212> DNA <213> Artificial Sequence <400> 905 gctagaaact gataagccac aggctaatat ggtgaatgaa gaactgacag atacagcacg 60 ttattcaacc aattcaggtc aacaattgtt tgacgtctta gcagatgacc tactaacaga 120 tgaccaagat gagggtttct taattggtaa catttataag tacattaaac gccacaaaga 180 aaaaggtggc attactgacc ttgaaaa 207 <210> 906 <211> 206 <212> DNA <213> Artificial Sequence <400> 906 tggaacattg tcatgagaga cacgggcttt acattgggcg caaactactt tagtaatcag 60 acacgtactt taaactatga taatgagaca acagcagtgg agcgtctaag gagtattatt 120 tcagactgtg gaggcgctaa gtttaccatt gactttgagt ttgaaaacat gcagttaaaa 180 agtaaaacaa tgaacattgt agagga 206 <210> 907 <211> 206 <212> DNA <213> Artificial Sequence <400> 907 gtagagagga cgctataaag aaatacgggg ctgagtctaa acaggttcag tctctaagca 60 ctcaaatcaa taacgccaca gcaaaataca atggtttaac tagtcaacta gaaaaaacct 120 ccaaggacta cattgacgct aagagtggac taacacaact ttctaaagaa atgaaacaga 180 acgaacgtga gactcaacaa caagta 206 <210> 908 <211> 206 <212> DNA <213> Artificial Sequence <400> 908 ctttccaaca ataagcaacc tctttgcgta gttcctcatc tgttagttta ccgccttgtt 60 caaagtcaac atccgtctct ttgacttcta accccatgaa accctcatgt tctttcagtg 120 aaaacccatt gtgttcatgg tacaggtcac aacctagaat aggagttttc ttcgtgttaa 180 agagtttata aataagtcct ctatca 206 <210> 909 <211> 206 <212> DNA <213> Artificial Sequence <400> 909 cacaggttgg caagcaacac caccaaatgt aacaggtggt caatacctat ggacacgtat 60 tatctggaca tttacagaga atagtaacca aaccacctac tcagtggcgc gctttggtca 120 ggatggtatt agtgtgactg gtactcaatc agagtatgta caaacaacta gttctgtaga 180 acctacctca ggatggagta caacac 206 <210> 910 <211> 206 <212> DNA <213> Artificial Sequence <400> 910 gtgttgtact ccatcctgag gtaggttcta cagaactagt tgtttgtaca tactctgatt 60 gagtaccagt cacactaaga ccatcctgac caaagcgcgc cactgagtag gttgtttggt 120 tactattatc tgtaaatgtc cagataatac gtgtccatag gtattgacca cctgttacat 180 ttggtggtgt tgcttgccaa cctgtg 206 <210> 911 <211> 206 <212> DNA <213> Artificial Sequence <400> 911 tatccccacg agttccatcc gccacctacg tcataaaagc ccgcgtttgt gcgtgctgtt 60 tgaattactc gcccgttacc tactacgtgc gagaagaacc cactgttgac gggtctgcgc 120 atatgatcgt ctgcctcgtt ttgcgctgta gatgatgaat tccccgtact gtgtacgtga 180 atttgtccat acggtcttac ccctac 206 <210> 912 <211> 206 <212> DNA <213> Artificial Sequence <400> 912 tggtatttag aagtacgtga cagtctattt actggttata actctgctag ttatgataat 60 aatgtgctcc gtggttattt acaaggtaaa gacgcgtttc agttgtcaca ggctgttatt 120 aagtcagttg atagaggact tatttataaa ctctttaaca cgaagaaaac tcctattcta 180 ggttgtgacc tgtaccatga acacaa 206 <210> 913 <211> 206 <212> DNA <213> Artificial Sequence <400> 913 tgagaactca tttcaatagc gcgcttttgt gcctcaatag ctttctcagt taaggagatt 60 gaacgtttta gaccctcctg tttagcctca agtgcgcccg ctgagtcccc tgcgtctttt 120 agtgcttgta cttgttgttg agtctcacgt tcgttctgtt tcatttcttt agaaagttgt 180 gttagtccac tcttagcgtc aatgta 206 <210> 914 <211> 206 <212> DNA <213> Artificial Sequence <400> 914 agacgtcaag ggcgtttagc ataacctaag gaggcttaag cctccttttt tgtgttataa 60 tgattagaga tagaaaggag aatgattcaa tgaaaattga aaaacaaatg cgctcaggtt 120 taccacacgt aggggtaaga ccgtatggac aaattcacgt acacagtacg gggaattcat 180 catctacagc gcaaaacgag gcagac 206 <210> 915 <211> 206 <212> DNA <213> Artificial Sequence <400> 915 gtgttgtact ccatcctgag gtaggttcta cagaactagt tgtttgtaca tactctgatt 60 gagtaccagt cacactaaga ccatcctgac caaagcgcgc cactgagtag gttgtttggt 120 tactattctc tgtaaatgtc cagataatac gtgtccatag gtattgacca cctgttacat 180 ttggtggtgt tgcttgccaa cctgtg 206 <210> 916 <211> 205 <212> DNA <213> Artificial Sequence <400> 916 ccaatacaat acctacgcgc tcagaaatgt catcacagaa cgcgtctgta atacgttcag 60 cctcctcatc atgaggactg taggcgtgac agtctgtgtt gctctgtaac atggtaacat 120 ggtccctaat tccctcgtag aagtcagcca taattaattg cccaatcaca catgttagaa 180 attgaaaacg tgggtcatat aaccc 205 <210> 917 <211> 205 <212> DNA <213> Artificial Sequence <400> 917 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgatt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaattc cctcaggaat atcgtctaat gaaagttgtt cataattata taactcttgt 180 tcttcttgct cgcgctcaat acgct 205 <210> 918 <211> 205 <212> DNA <213> Artificial Sequence <400> 918 tatactctgt catttaccca caagcgcaag agtttaaaag tggtgatagt gataataaag 60 taggtacgtt cttaggtaaa gttggggaca aggtatacga acttgtcaaa ggtaaccctc 120 aatttaatga gggatatttc aacgatagaa cgaacgataa gtacagatac cttggtgaat 180 gtgcgtattt tcaaaacggt gcgct 205 <210> 919 <211> 205 <212> DNA <213> Artificial Sequence <400> 919 accacgtata tagtttacca cgttctgtaa tgtgttggat gaacggggta gcatggtcat 60 tttgttctag tttaaagatt tttacgtaaa acgtacctac aaacgaaggg tctataacaa 120 acagcacttc tatcttattg attgctttat tttgggtagt tatactagca gaataccgca 180 cccagttgtc tgtacttgtg tttgt 205 <210> 920 <211> 205 <212> DNA <213> Artificial Sequence <400> 920 aaacaaggtt taggtataat taccctaagt gggtctccaa agctcagagg agagcttcta 60 gaggcgtcag gaacgcacta tgtatcaatc agctttcaat catcatggcg aacacctgaa 120 ttattgaaat ttatagataa agacactatg attgtttttg atgagtctca ctgtctagca 180 aacaggagcg caaacgtaac taagt 205 <210> 921 <211> 205 <212> DNA <213> Artificial Sequence <400> 921 tatactctgt catttaccca caagcgcaag agtttaaaag tggtgatagt gataataaag 60 taggtacgtt cttaggtcaa gttggggaca aggtatacga acttgtcaaa ggtaaccctc 120 aatttaaaga gggatatttc aacgatagaa cgaacgataa gtacagatac cttggtgaat 180 gtgcgtattt tcaaaacggt gcgct 205 <210> 922 <211> 205 <212> DNA <213> Artificial Sequence <400> 922 attctagagt caggaattgt aaagagtgct attacacaga tgattgacgt ctgcgatgcg 60 gtagatatgg gtaacctgtt agggggtaat gaaccagacc aaataattgg aaaaattggt 120 gacctcatga ataacctagc tactgcatac aatgacacaa ttgacgaact taactcgtca 180 aaataataaa aagcactaca cgttg 205 <210> 923 <211> 205 <212> DNA <213> Artificial Sequence <400> 923 ttaatcaagg aaattcgtga ggcacaagac gaacaaacag acgaggttaa ccctgacgag 60 caacctaagg atgaacaacc taaggatgat gaggcagacg aggttgaacc agaagaaaat 120 aaagatacat ctgtggacgc ggaacgtgct aaagcattag aggaagacgt ggacaaatta 180 gaaaaaggag aggctagaag tatgg 205 <210> 924 <211> 205 <212> DNA <213> Artificial Sequence <400> 924 acttagttac gtttgcgctc ctgtttgcta gacagtgaga ctcatcaaaa acaatcatag 60 tgtctttatc tataaatgtc aataattcag gtgttcgcca tgatgattga aagctgattg 120 atacatattg cgttcctgac gcctctagaa gctctcctct gagctttgga gacccactta 180 gggtaattat acctaaacct tgttt 205 <210> 925 <211> 205 <212> DNA <213> Artificial Sequence <400> 925 tcctatccct gaaaaagaat tgtttattgt tgactctcac gcgtgggtag caacaacggg 60 tggtggtatt gttcagacag aggctaacga tagaacaccc tatagacaat attccaaaca 120 ggggtattgt gaaatttctt cccgtcctga cggtcagtgt gattgggagg atatgttaaa 180 ttgggttttg gcgtttattg agaca 205 <210> 926 <211> 205 <212> DNA <213> Artificial Sequence <400> 926 tcatacattt ctgtagacga gtgggaaaag gcgtacacag acgaggagtt tgacatcaca 60 gggcgtgaag tatttattgg tatagaccta gcacgagtaa atgacttgac cgctgttacg 120 tgggttagtc ctatccctga aaaagaattg tttattgttg actctcacgc gtgggtagca 180 acaacgggtg gtggtattgt tcaga 205 <210> 927 <211> 205 <212> DNA <213> Artificial Sequence <400> 927 gggttatatg acccacgttt tcaatttcta acatgtgtga ttgggcaatt aattatggct 60 gacttctccg agggaatgag ggaccatgtt accatgttac cgagcaacac agactgtcac 120 gcctacattc ctcatgatga ggaggctgaa cgtattacag acgcgttctg tgatgacatt 180 tctgagcgcg taggtattgt attgg 205 <210> 928 <211> 205 <212> DNA <213> Artificial Sequence <400> 928 ttaatcaagg aaattcgtga ggcacaagac gaacaaacag acgaggttaa ccctgacgag 60 caacctaagg atgaacaccc taaggatgat gaggcagacg aggttgaacc agaagaaaat 120 aaagataaat ctgtggacgc ggaacgtgct aaagcattag aggaagacgt ggacaaatta 180 gaaaaaggag aggctagaag tatgg 205 <210> 929 <211> 205 <212> DNA <213> Artificial Sequence <400> 929 ttatacacaa tatctgatgg gatgagtttg ttgtcacgtt taatagcaac gctgtgttct 60 ttgagtagct catttaattc ctcagtgttt ctatatccca caatcgcatt ataagaccgt 120 ccacctacat actgtttctc ttctatacag tagcgttctc taaaagattt ccacgttcca 180 gagtataaac ctgcgatttt caatt 205 <210> 930 <211> 205 <212> DNA <213> Artificial Sequence <400> 930 ctttaaacta gaacaaaatg accatgctac cccgttcatc caacacatta cagaacgtgg 60 taaactatat acgtggtctt caattggcac aggactagac gcgtctacaa ttccaatgac 120 tcgcaccacg caaacatata ccattcaaaa tgaagctact aaagttctca gattgagcct 180 aaatgtatat ggtaatgcac acgtt 205 <210> 931 <211> 205 <212> DNA <213> Artificial Sequence <400> 931 caacgtgtag tgctttttat tattttgacg agttaagttc gtcaattgtg tcattgtatg 60 cagtagctag gttattcctg aggtcaccaa tttttccaat tatttggtct ggttcattac 120 cccctaaaag gttacccata tctaccgcat cgcagacgtc aatcatctgt gtaatagcac 180 tctttacaat tcctgactct agaat 205 <210> 932 <211> 205 <212> DNA <213> Artificial Sequence <400> 932 catgggttaa aaaggactca gggtacaggc gatttactaa agtggtaatc tccatgagtc 60 gtaagaacgg taaatcatta ttaatcgcgg gtattgcatt atatgaactt ctttacgaac 120 gttcgcccat ggcgtcccgt caaatatatt ctacagccaa tacaaaagac caagcgtcta 180 tttgtttccg catgattaag acaca 205 <210> 933 <211> 205 <212> DNA <213> Artificial Sequence <400> 933 agcgtattga gcgcgagcaa gaagaacaag agttatataa ttatgaacaa ctttcattag 60 acgatattcc tgagggactt actaaggaag ggtggttgat ttacgaggac cttgttccac 120 aacttaatca gctaccaatt tcaaaactag acgctggcat gctagtcatt tattgtaata 180 cttacgctat ttacagtcag gcaac 205 <210> 934 <211> 205 <212> DNA <213> Artificial Sequence <400> 934 gggttatatg acccacgttt tcaatttcta acatgtgtga ttgggcaatt aattatggct 60 gacttctacg agggaatgag ggaccatgtt accatgttac agagcaacac agactgtcac 120 gcctacagtc ctcatgatga ggaggctgaa cgtattacag acgcgttctg tgatgacatt 180 tctgagcgcg taggtattgt attgg 205 <210> 935 <211> 205 <212> DNA <213> Artificial Sequence <400> 935 acttagttac gtttgcgctc ctgtttgcta gacagtgaga ctcatcaaaa acaatcatag 60 tgtctttatc tataaatgtc aataattcag gtgttcgcca tgatgattga aagctgattg 120 atacatagtg cgttcctgac gcctctagaa gctctcctct gagctttgga gacccactta 180 gggtaattat acctaaacct tgttt 205 <210> 936 <211> 205 <212> DNA <213> Artificial Sequence <400> 936 caacgtgtag tgctttttat tattttgacg agttaagttc gtcaattgtg tcattgtatg 60 cagtagctag gttattcctg aggtcaccaa tttttccaat tatttggtct ggttcattac 120 cccctaacag gttacccata tctaccgcat cgcagacgtc aatcatctgt gtaatagcac 180 tctttacaat tcctgactct agaat 205 <210> 937 <211> 205 <212> DNA <213> Artificial Sequence <400> 937 ccatacttct agcctctcct ttttctaatt tgtccacgtc ttcctctaat gctttagcac 60 gttccgcgtc cacagatgta tctttatttt cttctggttc aacctcgtct gcctcatcat 120 ccttagggtg ttcatcctta ggttgctcgt cagggttaac ctcgtctgtt tgttcgtctt 180 gtgcctcacg aatttccttg attaa 205 <210> 938 <211> 205 <212> DNA <213> Artificial Sequence <400> 938 ttatacacaa tatctgatgg gatgagtttg ttgtcacgtt taatagcaac gctgtgttct 60 ttgagtagct catttaagtc ctcagtgttt ctatatccca caatcgcatt ataagaccgt 120 ccacctacat actgtttctc ttctatacag tagcgttctc taaaagattt ccacgttcca 180 gagtataaac ctgcgatttt caatt 205 <210> 939 <211> 205 <212> DNA <213> Artificial Sequence <400> 939 tatactctgt catttaccca caagcgcaag agtttaaaag tggtgatagt gataataaag 60 taggtacgtt cttaggtcaa gttggggaca aggtatacga acttgtcaaa ggtaaccctc 120 aatttaatga gggatatttc aacgatagaa cgaacgataa gtacagatac cttggtgaat 180 gtgcgtattt tcaaaacggt gcgct 205 <210> 940 <211> 204 <212> DNA <213> Artificial Sequence <400> 940 cgtcaaaacg gatggcaccc gctaacattt caccgtagac attgtggtct tgccaacgta 60 ccgtcatttc agtacgattg aacaaagtaa tagcttgttc taagtcacca atgaataata 120 gtttatcatt tgtgtcgttt ttaaagatag cgtcaggaag tacaattacc tctttaccaa 180 acaatgtttt accacttgcc attg 204 <210> 941 <211> 204 <212> DNA <213> Artificial Sequence <400> 941 tggcgtcccg tcaaatatat tctacagcca atacaaaaga ccaagcgtct atttgtttcc 60 gcatgattaa gacacaacta caggctgtta gaaagaaatc taaacaggtt cgtgagttta 120 caaaagtaaa caaatatgac attgagacaa aagatgactc tttttgtaaa gctctagcct 180 cagactcatc tgtattagat gggt 204 <210> 942 <211> 204 <212> DNA <213> Artificial Sequence <400> 942 ggcaagacac tcatggcatt agaatcgttt aaaaaatcag ggctaaagaa actcgtagta 60 gtgtgccttg cgtctatggt gtctgattgg gcttctgagg ggtctaaaca aggtttaggt 120 ataattaccc taagtgggtc tccaaagctc agaggagagc ttctagaggc gtcaggaacg 180 caatatgtat caatcagctt tcaa 204 <210> 943 <211> 204 <212> DNA <213> Artificial Sequence <400> 943 taaggaagtc ctacacattc gtgcaggttc caagactagt tacaagtcat acggtctgtt 60 acctaagggc gtcacgtttg aaacaaccaa acgtcaaacg ggtcaaaaga ttattaaaaa 120 caaccaaggg tattatgtaa ctaagaactc aggtaagaaa atacctgcct caggatgggt 180 cagtggatat tacctacaaa acac 204 <210> 944 <211> 204 <212> DNA <213> Artificial Sequence <400> 944 tgaaaatttt cccaatggat ggctctaacg cgcgcgtaaa cgaaccactc ctacatttct 60 ttctcagttt ttatgagtat gcagacacct caacatggag aggcaaagaa gttttcatac 120 aagggtggat aacaagcgat aacagacgta aactaataga ggaaatttct accttttttg 180 gtctaggtgt tgaggagtgg taac 204 <210> 945 <211> 204 <212> DNA <213> Artificial Sequence <400> 945 agtaatgact gagttactag ctaagttcga agcaacagaa gtaacttctc ttgatcaatt 60 gaaaacagcg tcaaacgtaa caattgaccc tgcttacaat caacgagttt ttgtttctca 120 aagcgcagtt gctcaattgg atacgttgaa agacgcagac ggacgataca ttattcaacc 180 aaacgtagca atggcaagtg gtaa 204 <210> 946 <211> 204 <212> DNA <213> Artificial Sequence <400> 946 gacagatatg cataatatgt attttatttt tgaccatgag gaatatattg agtcaaaatt 60 tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt gtacacaaag ccaaaatgta 120 cgtgcgtgtg aaaattttcc caatggatgg ctctaacgcg cgcgtaaacg aaccactcct 180 acatttcttt ctcagttttt atga 204 <210> 947 <211> 204 <212> DNA <213> Artificial Sequence <400> 947 cgtcaaaacg gatggcaccc gctaacattt caccgtagac attgtggtct tgccaacgta 60 ccgtcatttc agtacgtttg aacaaagtaa tagcttgttc taagtcacca atgaataata 120 gtttatcttt tgtgtcgttt ttaaagatag cgtcaggaag tacaattacc tctttaccaa 180 acaatgtttt accacttgcc attg 204 <210> 948 <211> 204 <212> DNA <213> Artificial Sequence <400> 948 tgtactgaga gcgtcaaaat tacctaccct acttacccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatataa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc ctgt 204 <210> 949 <211> 204 <212> DNA <213> Artificial Sequence <400> 949 gtgttttgta ggtaatatcc actgacccat cctgaggcag gtattttctt acctgagttc 60 ttagttacat aatacccttg gttgttttta ataatctttt gacccgtttg acgtttggtt 120 gtttcaatcg tgacgccctt aggtaacaga ccgtatgact tgtaactagt cttggaacct 180 gcacgaatgt gtaggacttc ctta 204 <210> 950 <211> 204 <212> DNA <213> Artificial Sequence <400> 950 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatataa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatcgtc gcaccatttc ctgt 204 <210> 951 <211> 204 <212> DNA <213> Artificial Sequence <400> 951 cgtcaaaacg gatggcaccc gctaacattt caccgtagac attgtggtct tgccaacgta 60 ccgtcatttc agtacgattg aacaaagtaa tagcttgttc taagtcacca atgaataata 120 gtttatcttt tgtgtcgttt ttaaagatag cgtcaggaag tacaattacc tctttaccaa 180 acaatgtttt accacttgcc attg 204 <210> 952 <211> 203 <212> DNA <213> Artificial Sequence <400> 952 tataaacgcg tacagtgaag catactttta tgagttcgag gaaataaact ggtcagaacg 60 ttacgcaagc ggtgattttg gttttggact gtaataaacg aacgaggcaa cccaactagg 120 gttgtctgtt tcgtgttata atttataaag aagttataat tggaggaggt tcaccatgga 180 acgaattata tatttaccta tga 203 <210> 953 <211> 203 <212> DNA <213> Artificial Sequence <400> 953 tctttttcat ctacaatgtt tatcctatcg cctacattta aatcagaagg tacattgact 60 acgtttactt cataattaaa agcaggttga cttttctttt tcaattcact aacagcaagt 120 gaagccactt tacctttatc aagggtgtca tacgttacag cacgtgtgaa caaacctcct 180 gttgttgata agagtctgga cca 203 <210> 954 <211> 203 <212> DNA <213> Artificial Sequence <400> 954 gagcattagg tggtacacca gaggggtcaa acaaccccat tacattaagt gggttctcgt 60 gggttgaccc agatgggcgt tttaaacttg agaatggggt tatgattgac acgcaagaag 120 ctcctaactg gtccagactc ttatcaacaa caggaggttt gttcacacgt gctgtaacgt 180 atgacaccct tgataaaggt aaa 203 <210> 955 <211> 203 <212> DNA <213> Artificial Sequence <400> 955 cgtgtctcac ggagtttcag gcgtctcatt gggttacctt ttttagattg tgtttcaatg 60 ttctctgtaa caacaccctc ttttattccc cctgtcatgg ggtcataact catggcgtta 120 ccttctaatg ttttccaaag ttcaaacatg gtacgcgcgt tctctttttg ttgcttagtt 180 ggtgtgaaaa tagtgttcat taa 203 <210> 956 <211> 203 <212> DNA <213> Artificial Sequence <400> 956 catggctaac gcgttgccat ggaactcctc ctctagaact ctgttaaaca gcatatttaa 60 ctcatcatca aacccattac cgtttaatac cttgttaata tactccgttt taaattgctc 120 taacatactt atccccctta gaataaatct tgacccgcat atacgcaaga gatgtttatc 180 catgcgcctg acggaatcgc act 203 <210> 957 <211> 203 <212> DNA <213> Artificial Sequence <400> 957 gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 60 gtacacaaag ccaaattgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 120 cgcgtaaacg aaccactcct acatttcttt ctcagttttt atgattatgc agacacctca 180 acatggagag gcaaagaagt ttt 203 <210> 958 <211> 203 <212> DNA <213> Artificial Sequence <400> 958 cgtgtctcac ggagtttcag gcgtctcatt gggttacctt ttttagattg tgtttcaatg 60 ttctctgtaa caacaacctc ttttattccc cctgtcatgg ggtcataact catggcgtta 120 ccttctactg ttttccaaag ttcaaacatg gtacgcgcgt tctctttttg ttgcttagtt 180 ggtgtgaaaa tagtgttcat taa 203 <210> 959 <211> 203 <212> DNA <213> Artificial Sequence <400> 959 catggctaac gcgttgccat ggaactcctc ctctagaact ctgttaaaca gcatatttaa 60 ctcatcatca aaccccttac cgtttaatac cttgttaata tactccgttt taaattgctc 120 taacataatt atccccctta gaataaatct tgacccgcat atacgcaaga gatgtttatc 180 catgcgcctg acggaatcgc act 203 <210> 960 <211> 203 <212> DNA <213> Artificial Sequence <400> 960 tctgtgtgta ttgtaggaat catcatgcct gttttctcct ttcgttcttc gtttattatg 60 ttagcatact ttttacgtca gcgcaagggg taacttgatg gggacacctt gttggtgtac 120 attttgatga taataattaa ataacaaaaa taataaaata acaaagggtg gtgtacggtt 180 ttttaagcgt tgggggacaa ggg 203 <210> 961 <211> 203 <212> DNA <213> Artificial Sequence <400> 961 gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 60 gtacacaaag ccaaattgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 120 cgcgtaatcg aaccactcct acatttcttt ctcagttttt atgattatgc agacacctca 180 acatggagag gcaaagaagt ttt 203 <210> 962 <211> 203 <212> DNA <213> Artificial Sequence <400> 962 agtgcgattc cgtcaggcgc atggataaac atctcttgcg tatatgcggg tcaagattta 60 ttctaagggg gataagtatg ttagagcaat ttaaaacgga gtatattaac aaggtattaa 120 acggtaaggg gtttgatgat gagttaaata tgctgtttaa cagagttcta gaggaggagt 180 tccatggcaa cgcgttagcc atg 203 <210> 963 <211> 203 <212> DNA <213> Artificial Sequence <400> 963 ttaatgaaca ctattttcac accaactaag caacaaaaag agaacgcgcg taccatgttt 60 gaactttgga aaacagtaga aggtaacgcc atgagttatg accccatgac agggggaata 120 aaagagggtg ttgttacaga gaacattgaa acacaatcta aaaaaggtaa cccaatgaga 180 cgcctgaaac tccgtgagac acg 203 <210> 964 <211> 203 <212> DNA <213> Artificial Sequence <400> 964 tataaacgcg tacagtgaag catactttta tgagttcgag gaaataaact ggtcagaacg 60 ttacgcaagc ggtgagtttg gttttggact gtaataaacg aacgaggcaa cccaactagg 120 gttgtctgtt tcgtgttata atttataaag aagttataat tggaggaggt tcaccatgga 180 acgaattata tatttaccta tga 203 <210> 965 <211> 202 <212> DNA <213> Artificial Sequence <400> 965 gttcttagtt accttataat tgacagcatt actagcaccc cattctggta cagaaacccc 60 tgttgttcgt gtaaattcac tagttccgtc agacactagt gttggttgtt cagattgccc 120 actaggtctt atatttgggt taggttcgtc attgaatgag aaacggtctg ttcctgtttc 180 gttgaaagcg tatgcggtac gt 202 <210> 966 <211> 202 <212> DNA <213> Artificial Sequence <400> 966 tgaaaattca cagcggttat gatacgtata ataatggttc ctatagacat ttgtcagttc 60 gccaaaatac agaggtcgcc actaaatact tgtcagaggg tggtacgagt attcatttac 120 accagagtgg tagttattac tcatatgaga acctcaaggc gcagaatggg ctagacgaaa 180 gacatgataa ggagtttata ca 202 <210> 967 <211> 202 <212> DNA <213> Artificial Sequence <400> 967 atgcttgttt atcaaggttg aacatggcac aaataaacgc tttagcaagt aacccatcaa 60 cacaaccata gaagcgtagc tcagtggcgt ctacgtcttt ccaacaataa gcaacctctt 120 tgcgtaggtc ctcatctgtt agtttaccgc cttgttcaaa gtcaacatcc gtctctttga 180 cttctaaccc catgaaaccc tc 202 <210> 968 <211> 202 <212> DNA <213> Artificial Sequence <400> 968 tggttctgac catattgacc cctatccata cttgcgtaaa tggggaatta gtaaagagca 60 gtttgctaaa gacaataaaa atgggtttgg tggaaatagt tccaatactg acaacaaacc 120 taaaccaaaa ccacaaccgt ctaaaccaaa aatcacagac acacgtgatt tccctgtagg 180 tagtaaagta aaagtacgcg cc 202 <210> 969 <211> 202 <212> DNA <213> Artificial Sequence <400> 969 tcctcatctg ttagtttacc gccttgttca aagtcaccat ccgtcacttt gacttctaac 60 cccatgaaac cctcctgttc ttacagagaa aaccctttgt gttcatggta caggtcacaa 120 cctagaatag gagttttctt cgtgttaaag agtttataaa taagtcctct atcatctgac 180 ttaataacag cctgtgacaa ct 202 <210> 970 <211> 202 <212> DNA <213> Artificial Sequence <400> 970 cgttgtaccg cgcaaagcac tgtagccatt tgataggtat gcaggacgta ttgttgacac 60 tgctgtttta gttaatttag tggctcctgc tgttggtgta gccgttactg cgtcaaagat 120 tccccaagac tgtatactat tgtcctgtga accgtttaat aggatatttg gcgcagtgtc 180 ctcaggtaca gtgtccgtgg ta 202 <210> 971 <211> 202 <212> DNA <213> Artificial Sequence <400> 971 tccatctttg gctttgctat agataacatg gtctctcata tgctcaccca tatatgaacc 60 acgcttaccg ctcaattttg ctttactgtt agaccagtat ggtacgcgtt tgctaaattc 120 ctcagcaacc tcaggcgcta tgtcgttcat tattttattt gcctcacggt ctaagtcttt 180 acctagttca ccaagcgctt tg 202 <210> 972 <211> 202 <212> DNA <213> Artificial Sequence <400> 972 cgttgtaccg cgcaaagcac tgtagccatt tgataggtat gcaggacgta ttgttgacac 60 tgctgtttta gttactttag tggctcctgc tgttggtgta gccgttactg cgtcaaagat 120 tccccaatac tgtatactat tgtcctgtga accgtttaat aggatatttg gcgcagtgtc 180 ctcaggtaca gtgtccgtgg ta 202 <210> 973 <211> 202 <212> DNA <213> Artificial Sequence <400> 973 tgttgtctca ttatcatagt ttaaagtacg tgtctgatta ctaaagtagt ttgcgcccaa 60 tgtaaagccc gtgtctctca tgacaatgtt ccagtagtat tgaaacgatt gaggtgacgt 120 ggttttatta gcaggtacaa cattattaag taagtcaagt gcaccatctt cacaacttat 180 ctcacgtgtt cccgccaatg gg 202 <210> 974 <211> 202 <212> DNA <213> Artificial Sequence <400> 974 tctttcatat agttatcaac aatttcgcct atattgtctg agtttctgac cataatggtc 60 tctagaaaca aatcaccgcg tgagttagta atcattagta gaattttagt catttttctt 120 accctcacca tatccgtcaa ggtatgccac tgcctcacgt atcgttgtat catgtttaat 180 cttgtctcta aactcctcag cg 202 <210> 975 <211> 202 <212> DNA <213> Artificial Sequence <400> 975 gttcttagtt accttataat tgacagcatt actagcaccc cattctggta cagaaacccc 60 tgttgttcgt gtaatttcac tagttccgtc agacactagt gttggttgtt cagattgccc 120 actaggtatt atatttgggt taggttcgtc attgaatgag aaacggtctg ttcctgtttc 180 gttgaaagcg tatgcggtac gt 202 <210> 976 <211> 202 <212> DNA <213> Artificial Sequence <400> 976 ttacattttg atgaatcaca agagcagtta gttaaagtta aagaaatggc gcagttgggt 60 aattatctaa tttatagacg acataacgga gatagtgcct gtcttactat catggacttc 120 acacacaccc cattggcggg aacacgtgag ataagttgtg aagatggtgc acttgactta 180 cttaataatg ttgtacctgc ta 202 <210> 977 <211> 202 <212> DNA <213> Artificial Sequence <400> 977 agcttgtttg aattgttttg ttagtttgtc aagtgtatta cctagttcag cggttccgtc 60 aatacctaaa ccaaacttca tatttcctac tggttttccg ctttgcacca tgtgttaatc 120 agctcctatt ttctctagct tttcaagttc ctcaggactt aagaaacgct taataaagtc 180 agcgccatcc atcacctttt ct 202 <210> 978 <211> 202 <212> DNA <213> Artificial Sequence <400> 978 tttatacgct acagacctaa tgactactgt ggcattcagt gagtaccttg ataaaacagg 60 taagaaaatt gatttgttac tcctagaggc taactatgac ggtgctgtaa ttggttatag 120 tgaatatctg aaaattcaca gcggttatga tacgtataat aatggttcct atagacattt 180 gtcagttcgc caaaatacag ag 202 <210> 979 <211> 202 <212> DNA <213> Artificial Sequence <400> 979 ttctgtacat ctttagacaa tgcgtctaaa gacttttcta tcacgtgttg aggtggttgt 60 ttgatagttc caaactcaat aaagtgcgcg cgccacgcaa cctcatcatc aaagccaatt 120 tctacatctc catctttggc tttgctatag ataacatggt ctctcatatg ctcacccata 180 tatgaaccac gcttaccgct ca 202 <210> 980 <211> 202 <212> DNA <213> Artificial Sequence <400> 980 tactacgtta agcgcgtata gtgctaattc agtaggtgag tcaccgtcaa ttaatacagt 60 atcaataaca ttagacacag ttactaaagc actgaagaca agtaactcag cagactcaat 120 acccgttttc tcatttaact cacgcgcctt ttcaaccact aaatcaccta attttgtagt 180 atctaaattc atgtctattt tc 202 <210> 981 <211> 202 <212> DNA <213> Artificial Sequence <400> 981 tctttcatat agttatcaac aatttcgcct atattgtctg agtttctgac cataatggtc 60 tctagaaaca aatccccgcg tgagttagta atcattagta gaattttagt catttttctt 120 accctcaaca tatccgtcaa ggtatgccac tgcctcacgt atcgttgtat catgtttaat 180 cttgtctcta aactcctcag cg 202 <210> 982 <211> 202 <212> DNA <213> Artificial Sequence <400> 982 tctttcatat agttatcaac aatttcgcct atattgtctg agtttctgac cataatggtc 60 tctagaaaca aatccccgcg tgagttagta atcattagta gaattttagt catttttctt 120 accctcacca tatccgtcaa ggtatgccac tgcctcacgt atcgttgtat catgtttaat 180 cttgtctcta aactcctcag cg 202 <210> 983 <211> 202 <212> DNA <213> Artificial Sequence <400> 983 tggttctgac catattgacc cctatccata cttgcgtaaa tggggaatta gtaaagagca 60 gtttgctaaa gacaataaaa atgggtttgg tggaaatagt tccaatactg acaacaaacc 120 taaaccacaa ccacaaccgt ctaaaccaaa aatcacagac acacgtgatt tccctgtagg 180 tagtaaagta aaagtacgcg cc 202 <210> 984 <211> 202 <212> DNA <213> Artificial Sequence <400> 984 taccacggac actgtacctg aggacactgc gccaaatatc ctattaaacg gttcacagga 60 caatagtata cagtcttggg gaatctttga cgcagtaacg gctacaccaa cagcaggagc 120 cactaaagta actaaaacag cagtgtcaac aatacgtcct gcatacctat caaatggcta 180 cagtgctttg cgcggtacaa cg 202 <210> 985 <211> 202 <212> DNA <213> Artificial Sequence <400> 985 gaaaatagac atgaatttag atactacaaa attaggtgat ttagtggttg aaaaggcgcg 60 tgagttaaat gagacaacgg gtattgagtc tgctgagtta cttgtcttca gtgctttagt 120 aactgtgtct aatgttattg atactgtatt aattgacggt gactcaccta ctgaattagc 180 actatacgcg cttaacgtag ta 202 <210> 986 <211> 202 <212> DNA <213> Artificial Sequence <400> 986 gttcttagtt accttataat tgacagcatt actagcaccc cattctggta cagaaacccc 60 tgttgttcgt gtaatttcac tagttccgtc agacactagt gttggttgtt cagattgccc 120 actaggtctt atatttgggt taggttcgtc attgaatgag aaacggtctg ttcctgtttc 180 gttgaaagcg tatgcggtac gt 202 <210> 987 <211> 202 <212> DNA <213> Artificial Sequence <400> 987 agaaaaggtg atggatggcg ctgactttat taagcgtttc ttaagtcctg aggaacttga 60 aaagctagag aaaataggag ctgattaaca catggtgcaa agcggaaaac cagtaggaaa 120 tatgaagatt ggtttaggta ttgacggaac cgctgaacta ggtaatacac ttgacaaact 180 aacaaaacaa ttcaaacaag ct 202 <210> 988 <211> 201 <212> DNA <213> Artificial Sequence <400> 988 tttgcgtggt gcgagtcatt ggaattgtag acgcgtctag tcctgtgcca attgaatacc 60 acgtatatag tttaccacgt tctgtaatgt gttggatgaa cggggtagca tggtcatttt 120 gttctagatt aaagtttttt acgtaaaacg tacctacaaa cgaagggtct ataacaaaca 180 gcacttctat cttattgatt g 201 <210> 989 <211> 201 <212> DNA <213> Artificial Sequence <400> 989 taggttctaa ataagcttta ccgttgtcag aggtatatac ctctaatgtg tcacctgtgt 60 tagggacacc accaattttg tttaggtcct cgttaaatcg ctctgtaacc tcatcttttt 120 tagtccagtc ttttgtctta ctattgtagt cctctttgta caatgttaat gtgtacagtt 180 tagaatagtc ctcaggacac a 201 <210> 990 <211> 201 <212> DNA <213> Artificial Sequence <400> 990 agcacttgta aacaactttt tacatccctt tttataaaat aatatggtat aatatgtgta 60 tacttattat acattgtttt tctccctaaa aagcactaca cgctgattcc tcccaacgtg 120 tagtgctgtt tattattttg acgagttaag ttcgtcaatt gtgtcattgt atgcagtagc 180 taggttattc atgaggtcac c 201 <210> 991 <211> 201 <212> DNA <213> Artificial Sequence <400> 991 catgagtttg acctaaataa aaaaggtaag cccgtagcta aaggaacgta tactgaccct 60 aatactggtt atggtatgga ttttggcgcg ggaggtgtcc acggagctgg tgaactgctt 120 attcacattg gacgctgtct catgcgtgac tacggtagtt tgtaccctaa tgtgtatgtg 180 aattttgatg ttctttctcg t 201 <210> 992 <211> 201 <212> DNA <213> Artificial Sequence <400> 992 gcggatagcc tagcacaatt ccaagtgcat aatcttctcc gtgttttctt gacaatttag 60 aaaactcatc caagtgctct aacttggaga caacaagcat gccactatat acgtaagttg 120 tgaagtgttc ccttacaata tttgtaagtt ctgacaccct aataaagatg gcgtctctca 180 gtcccaaatt aaatgccaca g 201 <210> 993 <211> 201 <212> DNA <213> Artificial Sequence <400> 993 aacgatatac cattgttgga gtaggcagcc ttttcgtgca ggttgatggt attgatgaat 60 ggttctacta tgaccgtttt gaacgtgact atgttaatga gggaattgaa tatagtttga 120 aagataatca tggtgctacc ttgagtgtcg ctaggttata taaagataaa acagtgatta 180 aaattactga ttttacgaat g 201 <210> 994 <211> 201 <212> DNA <213> Artificial Sequence <400> 994 catgagtttg acctaaataa aaaaggtaag cccgtagcta aaggaacgta tactgaccct 60 aatactggtt atgttatgga gtttggcgcg ggaggtgtcc acggagctgt tgaacagctt 120 attcacagtg gacgctttct catgcgtgac tacggtagtt tgtaccctaa tgtgtatgtg 180 aattttgatg ttctttctcg t 201 <210> 995 <211> 201 <212> DNA <213> Artificial Sequence <400> 995 ttactcgtgc taggtctata ccaataaata cttcacgccc tgtgatgtca aactcctcgt 60 ctgtgtacgc cttgtcccac tcgtctacag aaatgtatga cgttgcttgg tccgcaaccc 120 aaaaattaag ctccttagtt aggaagttgg tgagattacc tttagcctct ccctctgtct 180 ttttagcccg tttgtgttct a 201 <210> 996 <211> 201 <212> DNA <213> Artificial Sequence <400> 996 gtttatatac ttatgcgttt gttctaagga gtgatacaat gaaatacaac caatttaagg 60 ggtttcctct cattgcgcgt actaaaattc ccgcgataaa tgagtggcaa gctcaagaga 120 gttacaaaac attaggtaat attagaaaca tgaataaagg ggtcttatgt ggggaacaat 180 acaaattatt agtagtagac t 201 <210> 997 <211> 201 <212> DNA <213> Artificial Sequence <400> 997 aagtgattca taactagagt ccatttttga gaagtcgttt agcatacttt gagtaacatc 60 agcctgtgtc gctttgccgt ctttgaatgc ttgaaaaacg tctcttgttt tctgagaaaa 120 catatccctg ttgtcatcta gccgtccgtc aacaatagag ataccaattt cttttactag 180 gtcgttcacc ttatcaaggt t 201 <210> 998 <211> 201 <212> DNA <213> Artificial Sequence <400> 998 agcacttgta aacaactttt tacatccctt tttataaaat aatatggtat aatatgtgta 60 tacttattat acagtgtttt tctccctaaa aagcactaca cgctgattcc tcccaacgtg 120 tagtgctttt tattattttg acgagttaag ttcgtcaatt gtgtcattgt atgcagtagc 180 taggttattc atgaggtcac c 201 <210> 999 <211> 201 <212> DNA <213> Artificial Sequence <400> 999 tccaagggaa gtttttccgt atttggttat aacaaccaac attcaggtgg tctccatgaa 60 tgtgacttat aaacagtaag tgacagtcct gtaaatcttt ttttaatact ttaaatgaaa 120 gtcctatatc aatcatcatt tttataccat tctgaaatgt taatttaacc gcgttaccta 180 ctgacccact gcttataatc t 201 <210> 1000 <211> 201 <212> DNA <213> Artificial Sequence <400> 1000 ggaataccca agttaaatca ctagcctcaa tgtaaatgct atctgtttct aagtcaagca 60 atgcctcacg tccaatgagt aactcctcct tacctacagg cggttctact gtacctgtaa 120 caataaccgg tgtcactttt gcttttcgcc atttattaat cgttacagta atcatttatt 180 tttcctcctt attagacatt a 201 <210> 1001 <211> 201 <212> DNA <213> Artificial Sequence <400> 1001 tttgcgtggt gcgagtcatt ggaattgtag acgcgtctag tcctgtgcca attgaatacc 60 acgtatatag tttcccacgt tctgtaatgt gttggatgaa cggggtagca tggtcatttt 120 gttctagttt aaagtttttt acgtaaaacg tacctacaaa cgaagggtct ataacaaaca 180 gcacttctat cttattgatt g 201 <210> 1002 <211> 201 <212> DNA <213> Artificial Sequence <400> 1002 aaccttgata aggtgaacga cctagtaaaa gaaattggta tctctattgt tgacggacgg 60 ctagatgaca acatggatat gttttctcag aaaacaagag acgtttttca agcattcaaa 120 gacggcacag cgacacaggc tgatgttact caaagtatgc taaacgactt ctcaaaaatg 180 gactctagtt atgaatcact t 201 <210> 1003 <211> 201 <212> DNA <213> Artificial Sequence <400> 1003 ttctaaatgg gatgaggtac aagttacctt tgaacgattt agagagggct atgaggctcc 60 tacgtggctt acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt 120 aactcagaca aaaataaatg agtcccttac ctcattcttt gaacgatttg acagtgacta 180 caggcaactc aaagcgtggt a 201 <210> 1004 <211> 201 <212> DNA <213> Artificial Sequence <400> 1004 gcggatagcc tagcacaatt ccaagtgcat aatcttctcc gtgttttctt gacaatttag 60 aaaactcatc caattgctct aacttggaga caacaagcat gccactatat acgtaagttg 120 tgaagtggtc ccttacaata tttgtaagtt ctgacaccct aataaagatg gcgtctctca 180 gtcccaaatt aaatgccaca g 201 <210> 1005 <211> 201 <212> DNA <213> Artificial Sequence <400> 1005 agattataag cagtgggtca gtaggtaacg cggttaaatt aacatttcag aatggtataa 60 aaatgatgat tgagatagga ctttcattta aagtattaaa aaaagattta caggactgtc 120 acttactttt tataagtcac attcatggag accacctgaa tgttggttgt tataaccaaa 180 tacggaaaaa cttcccttgg a 201 <210> 1006 <211> 201 <212> DNA <213> Artificial Sequence <400> 1006 gcattagttg cccctgcggt tataccctca aatttatacg ttgaaggtgt gtcaccttgt 60 tttattgttt gccatgtact gagagcgtca aaattaccta ccctaattaa cccattattg 120 ttgctgactg cgtctattgt gacggaatat ttaactcctg ctggcaagta gttggttaat 180 aagtcattgc tataatagac t 201 <210> 1007 <211> 201 <212> DNA <213> Artificial Sequence <400> 1007 tccttagtta tcttacattt attatattat cagacgatta gtcatctgtc aacactattt 60 ttaaacttct ttcaaaattt ttctcaagtc tctaagttgt gcgtctgtta agtgtacgct 120 tactacaaca ttcgtaaaat cagtaatttt aatcactgtt ttatctttat ataacctagc 180 gacactcaag gtagcaccat g 201 <210> 1008 <211> 201 <212> DNA <213> Artificial Sequence <400> 1008 taggttctaa ataagcttta ccgttgtcag aggtatatac ctctaatgtg tcacctgtgt 60 tagggacacc acccattttg tttaggtcct cgttaaatcg ctctgtaacc tcatcttttt 120 tagtccattc ttttgtctta ctattgtagt cctctttgta caatgttaat gtgtacagtt 180 tagaatagtc ctcaggacac a 201 <210> 1009 <211> 201 <212> DNA <213> Artificial Sequence <400> 1009 tttatcaagg tactcactga atgccacagt agtcattagg tctgtagcgt ataaaaaact 60 ttgaccgttt gaggttccga taatgcctaa gttttgaacc tcatgaggag cgtctaaaaa 120 cgtacacact acgccactca cgtcaatagt ggtaccgtgt tccactataa tgttaacggg 180 tgccttacct tttgaaacaa g 201 <210> 1010 <211> 201 <212> DNA <213> Artificial Sequence <400> 1010 ttactcgtgc taggtctata ccaataaata cttcacgccc tgtgatgtca aactcctcgt 60 ctgtgtacgc cttttcccac tcgtctacag aaatgtatga cgttgcttgg tccgcaaccc 120 aaaaattcag ctccttagtt aggaagttgg tgagattacc tttagcctct ccctctgtct 180 ttttagcccg tttgtgttct a 201 <210> 1011 <211> 201 <212> DNA <213> Artificial Sequence <400> 1011 cttgtttcaa aaggtaaggc acccgttaac attatagtgg aacacggtac cactattgac 60 gtgagtggcg tagagtgtac gtttttagac gctcctcatg aggttcaaaa cttaggcatt 120 atcggaaact caaacggtca aagtttttta tacgctacag acctaatgac tactgtggca 180 ttcagtgagt accttgataa a 201 <210> 1012 <211> 201 <212> DNA <213> Artificial Sequence <400> 1012 tttatcaagg tactcactga atgccacagt agtcattagg tctgtagcgt ataaaaaact 60 ttgaccgttt gagtttccga taatgcctaa gttttgaacc tcatgaggag cgtctaaaaa 120 cgtacacact acgccactca cgtcaatagt ggtaccgtgt tccactataa tgttaacggg 180 tgccttacct tttgaaacaa g 201 <210> 1013 <211> 201 <212> DNA <213> Artificial Sequence <400> 1013 agcacttgta aacaactttt tacatccctt tttataaaat aatatggtat aatatgtgta 60 tacttattat acagtgtttt tctccctaaa aagcactaca cgctgattcc tcccaacgtg 120 tagtgctgtt tattattttg acgagttaag ttcgtcaatt gtgtcattgt atgcagtagc 180 taggttattc atgaggtcac c 201 <210> 1014 <211> 201 <212> DNA <213> Artificial Sequence <400> 1014 caatcaataa gatagaagtg ctgtttgtta tagacccttc gtttgtaggt acgttttacg 60 taaaaaactt taatctagaa caaaatgacc atgctacccc gttcatccaa cacattacag 120 aacgtgggaa actatatacg tggtattcaa ttggcacagg actagacgcg tctacaattc 180 caatgactcg caccacgcaa a 201 <210> 1015 <211> 201 <212> DNA <213> Artificial Sequence <400> 1015 agtctactac taataatttg ttttggtccc cacataagac ccctttattc atgtttctta 60 ttttacctaa tgtattgtaa ctctcttgag cttgccactc ttttatcgcg ggaattttag 120 tacgcgcatt gagaggaaac cccttaaatt ggttgtattt cattgtatca ctccttagaa 180 caaacgcata agtatataaa c 201 <210> 1016 <211> 201 <212> DNA <213> Artificial Sequence <400> 1016 aagtgattca taactagagt ccatttttga gaagtcgttt agcatacttt gagtaacatc 60 agcctgtgtc gctgtgccgt ctttgaatgc ttgaaaaacg tctcttgttt tctgagaaaa 120 catatccctg ttgtcatcta gccgtccgtc aacaatagag ataccaattt cttttactag 180 gtcgttcacc ttatcaaggt t 201 <210> 1017 <211> 201 <212> DNA <213> Artificial Sequence <400> 1017 gcggatagcc tagcacaatt ccaagtgcat aatcttctcc gtgttttctt gacaatttag 60 aaaactcatc caagtgctct aacttggaga caacaagcat gccactatat acgtaagttg 120 tgaagtggtc ccttacaata tttgtaagtt ctgacaccct aataaagatg gcgtctctca 180 gtcccaaatt aaatgccaca g 201 <210> 1018 <211> 201 <212> DNA <213> Artificial Sequence <400> 1018 taggttctaa ataagcttta ccgttgtcag aggtatatac ctctaatgtg tcacctgtgt 60 tagggacacc acccattttg tttaggtcct cgttaaatcg ctctgtaacc tcatcttttt 120 tagtccagtc ttttgtctta ctattgtagt cctctttgta caatgttaat gtgtacagtt 180 tagaatagtc ctcaggacac a 201 <210> 1019 <211> 201 <212> DNA <213> Artificial Sequence <400> 1019 catgagtttg acctaaataa aaaaggtaag cccgtagcta aaggaacgta tactgaccct 60 aatactggtt atggtatgga gtttggcgcg ggaggtgtcc acggagctgt tgaacagctt 120 attcacagtg gacgctttct catgcgtgac tacggtagtt tgtaccctaa tgtgtatgtg 180 aattttgatg ttctttctcg t 201 <210> 1020 <211> 201 <212> DNA <213> Artificial Sequence <400> 1020 ttctaaatgg gatgaggtac aagttacctt tgaacgattt agagagggct atgaggctcc 60 tacgtggctt acgattgata tgttcaaaac catgcaccca catttagcca atgtgaatgt 120 aactcagaca aaaataaatg agtcccttac ctcattcttt gaacgatttg acagtgacta 180 caggcaactc aaagcgtggt a 201 <210> 1021 <211> 201 <212> DNA <213> Artificial Sequence <400> 1021 tccaagggaa gtttttccgt atttggttat aacaaccaac attcaggtgg tctccatgaa 60 tgtgacttat aaacagtaag tgacagtcct gtaaatcttt ttttaatact ttaaatgaaa 120 gtcctatctc aatcatcatt tttataccat tctgaaatgt taatttaacc gcgttaccta 180 ctgacccact gcttataatc t 201 <210> 1022 <211> 201 <212> DNA <213> Artificial Sequence <400> 1022 tagaacacaa acgggctaaa aagacagagg gagaggctaa aggtaatctc accaacttcc 60 taactaagga gctgaatttt tgggttgcgg accaagcaac gtcatacatt tctgtagacg 120 agtgggacaa ggcgtacaca gacgaggagt ttgacatcac agggcgtgaa gtatttattg 180 gtatagacct agcacgagta a 201 <210> 1023 <211> 200 <212> DNA <213> Artificial Sequence <400> 1023 gtactacgtt aagcgcgtat agtgctaatt cagtaggtga gtcaccgtca attaatacag 60 tatcaataac attagtcaca gttactaaag cactgaagac aagtaactca gcagactcaa 120 tacccgtgtt ctcatttaac tcacgcgcct tttcaaccac taaatcacct aattttgtag 180 tatctaaatt catgtctatt 200 <210> 1024 <211> 200 <212> DNA <213> Artificial Sequence <400> 1024 gcgttgccat ggaactcctc ctctagaact ctgttaaaca gcatatttaa ctcatcatca 60 aacccattac cgattaatac cttgttaata tactccgttt taaattgctc taacataatt 120 atccccctta gaataaatct tgacccgcat atacgcaaga gatgtttatc catgcgcctg 180 acggaatcgc actatctact 200 <210> 1025 <211> 200 <212> DNA <213> Artificial Sequence <400> 1025 tttctttttt gttctttaaa cgctttttgt gaccgttgtg ccactgctac agttgtatca 60 tcatatgcgg gacttgaaac tagtgaaatc tctaccaatc taccaatttg gtcaattgtg 120 cggtgatatg tgtctgtgtt tgcgttgtat gaccacgtat cacttttaac cataaaccca 180 aacgaacact gtgataggtc 200 <210> 1026 <211> 200 <212> DNA <213> Artificial Sequence <400> 1026 caacgtacac accgtactct ttttcaacgt tttctggtgt catttcattt accccacttt 60 ctcaacgtga caaatctcaa tttctgagta gtctaaatgt tcttcatatt caaggtactg 120 taaccctgta ttaatagctt gttcaatagt atatgcgtca acgtgaatac tacagcaata 180 gtgctcatca atgttacggt 200 <210> 1027 <211> 200 <212> DNA <213> Artificial Sequence <400> 1027 agtagatagt gcgattccgt caggcgcatg gataaacatc tcttgcgtat atgcgggtca 60 agatttattc tatgggggat aattatgtta gagcaattta aaacggagta tattaacaag 120 gtattaaacg gtaatgggtt tgatgatgag ttaaatatgc tgtttaacag agttctagag 180 gaggagttcc atggcaacgc 200 <210> 1028 <211> 200 <212> DNA <213> Artificial Sequence <400> 1028 acccctctgg tgtaccacct aatgctcgta ttgctgtagt taactcataa atgttacctg 60 tagttacgat tgaatctacg tcacgcccaa cacgtagagt aatatctttc tcgtccccca 120 tctcctctac aatgttcatt gttttacttt ttaactgcat gttttcaaac tcaaagtcaa 180 tggtaaactt agcgcctcca 200 <210> 1029 <211> 200 <212> DNA <213> Artificial Sequence <400> 1029 ttctcattta actcacgcgc cttttcaacc actaaatcac ctaattttgt agtatctaaa 60 ttcatgtcta ttgtcctccc ttatttggtt gaaacaacca tttagaaaac attagtgaca 120 accctataac taatggcgtt aggtatgcaa tcaattttct gagtcctccc acgctttaat 180 gaacccctca atttctttga 200 <210> 1030 <211> 200 <212> DNA <213> Artificial Sequence <400> 1030 aaccattgtt ttcctcctta atattcaaca ctaacaatgt agtacggttg tattactaca 60 ttcacgggca cagagcttag tagcataatc tgaaaaacct ctcctgtttg catacgttca 120 ataacaatct ctggggaacc cttatatgtg taagagcgtc cgttgaccat gcagatggta 180 atggtacggg tctcattgct 200 <210> 1031 <211> 200 <212> DNA <213> Artificial Sequence <400> 1031 ataattaatt gcccaatcac acatgttaga aattgaaaac gtgggtcata taacccatta 60 aactctgcac ctgtggcacc aaacaatgta ttaataggca attttacccc atttactaac 120 acatacagtg gtaacgttac ttcgttcatt gtaatctctg tttcatctgt atatttagcc 180 tctagacgtt tatctaagag 200 <210> 1032 <211> 200 <212> DNA <213> Artificial Sequence <400> 1032 gcagaatacc gcacccagtt gtctgtactt gtgtttgtga ttgagacttt tccatcttcg 60 cgcgtactat cagagtaggt aacacgcaca attaattctg ttgttgctag actaccagtc 120 caccccttag agatgaatac actccctgat acagtgtacg ttgtaccgcg caaagcactg 180 tagccatttg ataggtatgc 200 <210> 1033 <211> 200 <212> DNA <213> Artificial Sequence <400> 1033 ctagtaatcg tttatccatg tttcacactc cttattatgt ttcttaaata attataacac 60 gcgtttatta accgcgggtg agttagctgt atcacattaa ttctaaaatg tcaagttcta 120 attctaagtt tcttttttgt tctttaaacg ctttttgtga ccgttgtgcc actgctacag 180 ttgtatcatc atatgcggga 200 <210> 1034 <211> 200 <212> DNA <213> Artificial Sequence <400> 1034 tactacgtca aaacggatgg cacccgctaa catttcaccg tagacattgt ggtcttgcca 60 acgtaccgtc atttcagtac gtttgaacaa agtaatagct tgttctaagt caccaatgaa 120 taatagtgta tcatttgtgt cgtttttaaa gatagcgtca ggaagtacaa ttacctcttt 180 accaaacaat gttttaccac 200 <210> 1035 <211> 200 <212> DNA <213> Artificial Sequence <400> 1035 gatgaggtac aagttacctt tgaacgattt agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgatcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataaatg agtcccttac ctcattcttt gaacgatttg acagtgacta caggcaactc 180 aaagcgtggt accctatacg 200 <210> 1036 <211> 200 <212> DNA <213> Artificial Sequence <400> 1036 gcagaatacc gcacccagtt gtctgtactt gtgtttgtga ttgagacttt tccatcttcg 60 cgcgtactat catagtaggt aacacgcaca attaattctg ttgttgctag actaccagtc 120 cacccctgag agatgaatac actccctgat acagtgtacg ttgtaccgcg caaagcactg 180 tagccatttg ataggtatgc 200 <210> 1037 <211> 200 <212> DNA <213> Artificial Sequence <400> 1037 cgcaaccaac gaacctctat tctagctgta tatgcaaaca acggtttaga cctaatggag 60 gcagtacagc aatatgagaa agtacgcgct gagggaatgc gtttacagga gcaagaaata 120 gaaaagacag tgactatacg cgtggatggg gaacaggatg aagttgagga tgagtttgtt 180 attgttaaga ttgctaaaaa 200 <210> 1038 <211> 200 <212> DNA <213> Artificial Sequence <400> 1038 ggcgtgtaaa ttgtacatga caacctgttt cagtgaacct cttgacgaga gtgagtttga 60 aataacacta atgagtaatt ggaaacgtga aaaaggtaga tgattatatg acacctgtta 120 ttaatgacag caatgagacc cgtaccatta ccatctgcat ggtcaacgga cgctcttaca 180 catataaggg ttccccagag 200 <210> 1039 <211> 200 <212> DNA <213> Artificial Sequence <400> 1039 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gactatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttctatagtc gcaccatttc 200 <210> 1040 <211> 200 <212> DNA <213> Artificial Sequence <400> 1040 tggtaacgtt acttcgttca ttgtaatctc tgtttcatct gtatatttag cctctagacg 60 tttatctaag aggtctttca ctaggtgctt attctcctca ggtacgttac gagaaagaac 120 atcaaaattc acatacacat tagggtacaa actaccgtag tcacgcatga gaaagcgtcc 180 aatgtgaata agctgttcaa 200 <210> 1041 <211> 200 <212> DNA <213> Artificial Sequence <400> 1041 gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa taagtcattg 60 ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt 120 gaatattata tagtcgcacc atttcctgtc caaccattaa tagttgggtc tttcgagaaa 180 tcataattca atactaaatt 200 <210> 1042 <211> 200 <212> DNA <213> Artificial Sequence <400> 1042 tgtatacact tttatagaga cggacgttat tatgctacaa ttgacaaaaa aggttttagt 60 ggtggttatc accttaaaca aacactaaat taggggagga atttaaatga acacatatac 120 agtttatgac cgtaacattg atgagcacta ttgctgtagt attcacgttg acgcatatac 180 tattgaacaa gctattaata 200 <210> 1043 <211> 200 <212> DNA <213> Artificial Sequence <400> 1043 tgtactgaga gagtcaaaat tacctaccct aattacccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttatatagtc gcaccatttc 200 <210> 1044 <211> 200 <212> DNA <213> Artificial Sequence <400> 1044 tactacgtca aaacggatgg cacccgctaa catttcaccg tagacattgt ggtcttgcca 60 acgtaccgtc atgtcagtac gtttgaacaa agtaatagct tgttctaagt caccaatgaa 120 taatagtgta tcatttgtgt cgtttttaaa gatagcgtca ggaagtacaa ttacctcttt 180 accaaacaat gttttaccac 200 <210> 1045 <211> 200 <212> DNA <213> Artificial Sequence <400> 1045 gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa taagtcattg 60 ctataataga ctcttctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt 120 gaatattata tagtcgcacc atttcctgtc caaccattaa tagtggggtc tttcgagaaa 180 tcataattca atactaaatt 200 <210> 1046 <211> 200 <212> DNA <213> Artificial Sequence <400> 1046 cgtatagggt accacgcttt gagttgcctg tagtcactgt caaatcgttc aaagaatgag 60 gtaagggact cagttatttt tgactgagtt acattcacat tggctaaatg tgggtgcatg 120 gttttgatca tatcaaacgt aagccacgta ggagcctcat agccctctct aaatcgttca 180 aaggtaactt gtacctcatc 200 <210> 1047 <211> 200 <212> DNA <213> Artificial Sequence <400> 1047 gcatacctat caaatggcta cagtgctttg cgcggtacaa cgtacactgt atcagggagt 60 gtattcatct ctcaggggtg gactggtagt ctagcaacaa cagaattaat tgtgcgtgtt 120 acctactctg atagtacgcg cgaagatgga aaagtctcaa tcacaaacac aagtacagac 180 aactgggtgc ggtattctgc 200 <210> 1048 <211> 200 <212> DNA <213> Artificial Sequence <400> 1048 gcgttgccat ggaactcctc ctctagaact ctgttaaaca gcatatttaa ctcatcatca 60 aacccattac cgattaatac cttgttaata tactccgttt taaattgctc taacataatt 120 atcccccata gaataaatct tgacccgcat atacgcaaga gatgtttatc catgcgcctg 180 acggaatcgc actatctact 200 <210> 1049 <211> 200 <212> DNA <213> Artificial Sequence <400> 1049 tttttagcaa tcttaacaat aacaaactca tcctcaactt catcctgttc cccatccacg 60 cgtatagtca ctgtcttttc tatttcttgc tcctgtaaac gcattccctc agcgcgtact 120 ttctcatctt gctgtactgc ctccattagg tctaaaccgt tgtttgcata tacagctaga 180 atagaggttc gttggttgcg 200 <210> 1050 <211> 199 <212> DNA <213> Artificial Sequence <400> 1050 cgctgtaggt acctcaggta caacagcacc atccacaggt tggcaagcaa caccaccaaa 60 tgtaacaggt ggtcaattcc tatgtacacg tattatcggg acatttacag ataatagtaa 120 ccaaacaccc tactcagtgg cgcgctttgg tcaggatggt attagtgtga ctggtactca 180 atcagagtat gtacaaaca 199 <210> 1051 <211> 199 <212> DNA <213> Artificial Sequence <400> 1051 ttatgagttg gttattttga cagacgctaa tgacatatta atgtctatag ccatccgtga 60 ctctgacgca acaggcaatg aagtgattgt tgaatactgg tacggtaaca agttactaaa 120 atctatcaag acagacgtaa ctaagtacaa atcatcttgg ttccgctgta caatgacacg 180 tgaccaaacg ggtaagaag 199 <210> 1052 <211> 199 <212> DNA <213> Artificial Sequence <400> 1052 aaactttaca aaagacatct taccaaaagt agggcaatat ttaggtgagg tgtttggtaa 60 gttacaacca atactggaac cggttggcga gtatattaaa accatcacgg agttattatg 120 gaatatgggc gccatcatgt ttgaaaaggt ttatccatta ttaaaaccca tactagacac 180 gatttttagt gcgttcggt 199 <210> 1053 <211> 199 <212> DNA <213> Artificial Sequence <400> 1053 ctagttacta cccaatttgt atacgtacca tttgaaagcg tatttctact ccttacccac 60 aaccacatac caatttgagg tgttggacgt gttgtactcc atcctgaggt aggttctaca 120 gaactaggtg tttgtacata ctctgattga gtaccagtca cactaatacc atcctgacca 180 aagcgcgcca ctgagtagg 199 <210> 1054 <211> 199 <212> DNA <213> Artificial Sequence <400> 1054 gacttgagga aaaaaccttt gaggaacagt tagaaaccct tgaggaaaca tattcatccc 60 tcttagaaag tagctggcaa ctctcagaga tagagaacgc tgactacttt cttttattac 120 aattgttggg taaagagtct aaacaagaaa aggtgatgga tggcgctgac tttattaagc 180 gtttcttaag tcctgagga 199 <210> 1055 <211> 199 <212> DNA <213> Artificial Sequence <400> 1055 tgtatactta ttatacattg tttttctccc taaaaagcac tacacgctga ttcctcccaa 60 cgtgtagtgc tttttattat tttgacgagt taagttcgtc aattgtgtca ttgtatgcag 120 tagctagttt attcatgagg tcaccaattt ttccaattat ttggtctggt tcattacccc 180 ctaaaaggtt acccatatc 199 <210> 1056 <211> 199 <212> DNA <213> Artificial Sequence <400> 1056 tgtatactaa aagcattagt tgcccctgcg gttataccct caaatttata cgttgaaggt 60 gtgtcacctt gatttattgt ttgccatgta ctgagagcgt caaaattacc taccctaatt 120 aacccattat tgttgctgaa tgcgtctatt gtgacggaat atttaactcc tgctggcaag 180 tagttggtta ataagtcat 199 <210> 1057 <211> 199 <212> DNA <213> Artificial Sequence <400> 1057 tgtatactaa aagcattagt tgcccctgcg gttataccct caaatttata cgttgaaggt 60 gtgtcacctt gttttattgt ttgccatgta ctgagagcgt caaaattacc taccctaatt 120 aacccatgat tgttgctgaa tgcgtctatt gtgacggaat atttaactcc tgctggcaag 180 tagttggtta ataagtcat 199 <210> 1058 <211> 199 <212> DNA <213> Artificial Sequence <400> 1058 cttcttaccc gtttggtcac gtgtcattgt acagcggaac caagatgatt tgtacttagt 60 tacgtctgtc tggatagatt ttagtaactt gttaccgtac cagtattcaa caatcacttc 120 attgcctgtt gcgtcagagt cacggatggc tatagacatt aatatgtcat tagcgtctgt 180 caaaataacc aactcataa 199 <210> 1059 <211> 199 <212> DNA <213> Artificial Sequence <400> 1059 tgtatactaa aagcattagt tgcccctgcg gttataccct caaatttata cgttgaaggt 60 gtgtcacctt gatttattgt ttgccatgta ctgagagcgt caaaattacc taccctaatt 120 aacccatgat tgttgctgaa tgcgtctatt gtgacggaat atttaactcc tgctggcaag 180 tagttggtta ataagtcat 199 <210> 1060 <211> 198 <212> DNA <213> Artificial Sequence <400> 1060 caaagaaatt gaggggttca ttaaagcgtg ggaggactca gaaaattgat tgcataccta 60 acgccattag ttatagggtt gtcactaatg ttttctaaat ggttgtttca accaaataag 120 ggaggaaaat agacatgaat ttagatacta caaaattagg tgatttagtg gttgaaaagg 180 cgcgtgagtt aaatgaga 198 <210> 1061 <211> 198 <212> DNA <213> Artificial Sequence <400> 1061 cctcgtctgt ttgttcgtct tgtgcctcac gaatttcctt gattaattta tccgcctcat 60 ctaatttacc ttgtgcgata agttcacggg cttctagtaa tcgtttatcc atgtttcaca 120 ctccttagta tgtttcttaa ataattataa cacgcgttta ttaaccgcgg gtgagttagc 180 tgtatcacat taattcta 198 <210> 1062 <211> 198 <212> DNA <213> Artificial Sequence <400> 1062 tactacgtta agcgcgtata gtgctaattc agtaggtgag tcaccgtcaa ttaatacagt 60 atcaataaca ttagtcacag ttactaaagc actgaagaca agtaactcag cagactcaat 120 acccgttgtc tcttttaact cacgcgcctt ttcaaccact aaatcaccta agtttgtagt 180 atctaaattc atgtctat 198 <210> 1063 <211> 198 <212> DNA <213> Artificial Sequence <400> 1063 ttctttgaca aaattacagg aggcgtaaaa aacatctgga acggtgccaa aaacatggct 60 aaaagtgcgt ttgataaggt tagcagtgtt gttggtgacg tttgggacta cgcaactaac 120 ccaagcacat tagttgaaaa agtattctct agcgtagtag acacctcagg tctcataaaa 180 tatcctctag acgttgcc 198 <210> 1064 <211> 198 <212> DNA <213> Artificial Sequence <400> 1064 tccgtctgag gtaattatta caccgtctaa acagtttttt gtaaatggtg agggtacaat 60 cagtatatca tctaaagttg tcaaaggcaa ggatgacatt actgataatt ttacttcgtt 120 tgtatggcgt agatatgacg cctcaaacgt attagacaca tcatggacag caacaggaaa 180 aacaatcaca gtaaatgc 198 <210> 1065 <211> 198 <212> DNA <213> Artificial Sequence <400> 1065 ggcaacgtct agaggatatt ttatgagacc tgaggtgtct actacgctag agaatacttt 60 ttcaactaat ttgcttgggt tagttgcgta gtcccaaacg tcaccaacaa cactgctaac 120 cttatcacac gcacttttag ccatgttttt ggcaccgttc cagatgtttt ttacgcctcc 180 tgtaattttg tcaaagaa 198 <210> 1066 <211> 198 <212> DNA <213> Artificial Sequence <400> 1066 caccattaat gtgtaagtgg tccatgtgtc cacctgacgc ccaattagtc catgtgtcat 60 gaatacccgt tccagttgtg cccacgcggt cacgtacttt attcagagca ctaacgtagc 120 caccttgggt tgtaaagtta tcaaaagcat agttacccgc ttgtcggtag ttacttgacc 180 cgttcatgct tgcaggaa 198 <210> 1067 <211> 198 <212> DNA <213> Artificial Sequence <400> 1067 ttttaataat cttttgaccc gtttgacgtt tggttgtttc aaacgtgacg cccttaggta 60 acagaccgta tgacttgtaa ctagtcttgg aacctgcacg aatgtgtagg acttccttag 120 atttcatggt ccatgttacc ttatccacta cctcccttgt ggctactgag tctttatact 180 tgagtagcca tctagatg 198 <210> 1068 <211> 198 <212> DNA <213> Artificial Sequence <400> 1068 gatttaaagt tatcaaaagc atagttaccc gcttgacggt atttacttga cccgttcatg 60 cttgcaggaa ctgctacgtc aatagcgttt cttgaaccgt gactatatgg gtctcctggt 120 ctatatccac ttgttacgcg cataccaggg tatttggcaa tcaccttacg cgctacatta 180 gtaaggtatt tatacaca 198 <210> 1069 <211> 198 <212> DNA <213> Artificial Sequence <400> 1069 tccgtctgag gtaattatta caccgtctaa acagtttttt gtaaaaggtg agggtacaat 60 cagtatatca gctaaatttg tcaaaggcaa ggatgacatt actgataatt ttacttagtt 120 tgtatggagt agatatgact cctcaaacgt attagacaca tcatggacag caacaggaaa 180 aacaatcaca gtaaatgc 198 <210> 1070 <211> 198 <212> DNA <213> Artificial Sequence <400> 1070 cttcatattt cctactggtt ttccgctttg caccatgtgt taatcagctc cttttttctc 60 tagcttttca tgttcctcag gacttaagaa acgcttaata aagtcagcgc catccatcac 120 cttttcttgt ttagactctt taccaaacaa ttgtaataaa agaaagtagt cagcgttctc 180 tatctctgag agttgcca 198 <210> 1071 <211> 198 <212> DNA <213> Artificial Sequence <400> 1071 ttctcactag tataaaacac taacgtatca tctaaatcat atacgtcaat catatcctcg 60 ttatactcaa tatcatgtaa tgttagttcc attctattca tcctcctcaa ataagtcata 120 tgttttaatc tctggtaatt ttggcaattt atacgtgcta atgtgtcccg tgtctatcaa 180 gtgaaaaata gtttctaa 198 <210> 1072 <211> 198 <212> DNA <213> Artificial Sequence <400> 1072 gcatttactg tgattgtttt tcctgttgct gtccatgatg tgtctaatac gtttgaggcg 60 tcatatctac tccatacaaa cgaagtaaaa ttatcagtaa tgtcatcctt gcctttgaca 120 actttagatg atatactgat tgtaccctca ccatttacaa aaaactgttt agacggtgta 180 ataattacct cagacgga 198 <210> 1073 <211> 198 <212> DNA <213> Artificial Sequence <400> 1073 ttctttgaca aaattacagg aggcgtaaaa aacatctgga acggtgccaa aaacatggct 60 aaaagtgcgt gtgataaggt tagcagtgtt gttggtgacg tttgggacta cgcaactaac 120 ccaagcacat tagttgaaaa agtattctct agcgtagtag acacctcagg tctcataaaa 180 tatcctctag acgttgcc 198 <210> 1074 <211> 198 <212> DNA <213> Artificial Sequence <400> 1074 atagaaacta tttttcactt gatagacacg ggacacatta gcacgtataa attgccaaaa 60 ttaccagaga ataaaacata tgacttattt gaggaggatg aatagaatgg aactaacatt 120 acatgatatt gagtataacg aggatatgat tgacgtatat gatttagatg atacgttagt 180 gttttatact agtgagaa 198 <210> 1075 <211> 198 <212> DNA <213> Artificial Sequence <400> 1075 ttagttgccc ctgcggttat accctcaaat ttatacgttg aaggtgtgtc accttgtatt 60 attgtttgcc atgtactgag agcgtcaaaa ttacctaccc taattaaccc attattgttg 120 ctgaatgagt ctattgtgac ggaatattta actcctgctg gcaagtagtt ggttaataag 180 tcattgctat aatagact 198 <210> 1076 <211> 197 <212> DNA <213> Artificial Sequence <400> 1076 ttctcactag tataaaacac taacgtatca tctaaatcat atacgtcaat catatcctcg 60 ttatactcaa aatcatgtaa tgttagttcc attctattca tcctcctcaa ataagtcata 120 tgttttattc tctggtaatt ttggcaattt atacgtgcta atgtgtcccg tgtctatcaa 180 gtgaaaaata gtttcta 197 <210> 1077 <211> 197 <212> DNA <213> Artificial Sequence <400> 1077 ttcccaccat agagctaagt agtgttcagc ctctacctca cctgttaata ctttcatagt 60 cattggatag tcctccatat gatagtgtcc gtttaggttt tgtgaggttg tactaatcat 120 taagttaagg ggttgtaatt gttgtgactg agatgactca ataacctcaa caatagaagt 180 atctttattc tcagcca 197 <210> 1078 <211> 197 <212> DNA <213> Artificial Sequence <400> 1078 tgttaccact gtttacaaaa cacgtcaact acttttttta aatttcttgt aattctttag 60 taagacaata tccctctgtt tttccatctg tacataaata taattgtggg aaaccccacg 120 cgctccagtc actaaaacca attacacgca caaccgtacc atctttaaag ttacaatcac 180 tatcccacgg tgtcaca 197 <210> 1079 <211> 197 <212> DNA <213> Artificial Sequence <400> 1079 ttagcctctc cctctgtctt tttagcccgt ttgtgttcta acatatgtgt gcgaacgtca 60 ggtttttcaa aaagagggtt agatttaaac cagttttcct cgtcatccgc ctcgtcaaaa 120 ctatccagtt cccaccatag agctaagtag tgttcagcct ctacctcacc tgttaatact 180 ttcatagtca ttggata 197 <210> 1080 <211> 197 <212> DNA <213> Artificial Sequence <400> 1080 ctctacacgt ttctgtacat ctttagacaa tgcgtctaaa gacttttcta tcacgtgttg 60 aggtggttga ttgatagttc caaactcaat aaagtgcgcg cgccacgcaa cctcatcatc 120 aaagccaatt tctacatatc catctttggc tttgctatag ataacatggt ctctcatatg 180 ctcacccata tatgaac 197 <210> 1081 <211> 197 <212> DNA <213> Artificial Sequence <400> 1081 ccttgcgctg acgtaaaaag tatgctaaca taataaacga agaacgaaag gagaaaacag 60 gcatgatgag tcctacaata cacacagaaa tgacaccaga agtaaaagac atttatccat 120 taacctattg tcgcgataag gtggacctac ctatagacat tgagtacacg aacagaggtt 180 cgcgctttgt cgttggt 197 <210> 1082 <211> 197 <212> DNA <213> Artificial Sequence <400> 1082 ctctacacgt ttctgtacat ctttagacaa tgcgtctaaa gacttttcta tcacgtgttg 60 aggtggttgt ttgatagttc caaactcaat aaagtgcgcg cgccacgcaa cctcatcatc 120 aaagccactt tctacatatc catctttggc tttgctatag ataacatggt ctctcatatg 180 ctcacccata tatgaac 197 <210> 1083 <211> 197 <212> DNA <213> Artificial Sequence <400> 1083 tgaggaatgt cttatttttg ccaatgatat ttttgaggcg tgtgagattg ctgaacactt 60 acagggtgta gaacgcgtta tagaagttgt gaggttggtg ctatgataaa aaagggttta 120 gagtgcagtg tgacaccgtg ggatagtgat tgtaacttta aagatggtac ggttgtgcgt 180 gtaattggtt ttagtga 197 <210> 1084 <211> 197 <212> DNA <213> Artificial Sequence <400> 1084 ccttgcgctg acgtaaaaag tatgctaaca taataaacga agaacgaaag gagaaaacag 60 gcatgatgat tcctacaata cacacagaaa tgacaccaga agtaaaagac atttatccat 120 taacctagtg tcgcgataag gtggacctac ctatagacat tgagtacacg aacagaggtt 180 cgcgctttgt cgttggt 197 <210> 1085 <211> 197 <212> DNA <213> Artificial Sequence <400> 1085 ttcgtgtggc ttgtttctga taaaaattcc cattagtgac tctctccttt atcgttgatg 60 ttatcaacct gctctaattc ctttgatagc ttaaaacttg tagccaaaca agcgccacct 120 aataccaaaa aacctacggt tatatctacc aaaaaggcac caatagccat aaaaacacac 180 gctagtatat acataat 197 <210> 1086 <211> 197 <212> DNA <213> Artificial Sequence <400> 1086 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctttag 60 tcgcaccatg tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaat 197 <210> 1087 <211> 197 <212> DNA <213> Artificial Sequence <400> 1087 gtttgttatt gttaagattg ctaaaaatga tttaggtaac cttgatgttg cgtatgagct 60 agtataacac cgttttacac ataaatggta taataacact atatgaaata agagagggag 120 attttaatga gtaaagaacc tgaaaaatta acagttgtag cagttgagga cgaggacaaa 180 agtttagtga ttagtgt 197 <210> 1088 <211> 197 <212> DNA <213> Artificial Sequence <400> 1088 tcctagttcg attattattt ttgttatagt tataattaaa gcatttgaat taccctgtat 60 actaaaagca ttagttgccc ctgcggttat accctcaaat ttatacgttg aaggtgtgtc 120 accttgtatt attgtttgcc atgtactgag agcgtcaaaa ttacctaccc taattaaccc 180 attattgttg ctgaatg 197 <210> 1089 <211> 197 <212> DNA <213> Artificial Sequence <400> 1089 attatgtata tactagcgtg tgtttttatg gctattggtg cctttttggt agatataacc 60 gtaggtttta tggtattagg tggcgcttgt ttggctacaa gttttaagct atcaaaggaa 120 ttagagctgg ttgataacat caacgataaa ggagagagtc actaatggga atttttatca 180 gaaacaagcc acacgaa 197 <210> 1090 <211> 197 <212> DNA <213> Artificial Sequence <400> 1090 attatgtata tactagcgtg tgtttttatg gctattggtg cctttttggt agatataacc 60 gtaggttttt tggtattagg tggcgcttgt ttggctacaa gttttaagct atcaaaggaa 120 ttagagctgg ttgataacat caacgataaa ggagagagtc actaatggga atttttatca 180 gaaacaagcc acacgaa 197 <210> 1091 <211> 197 <212> DNA <213> Artificial Sequence <400> 1091 accaacgaca aagcgcgaac ctctgttcgt gtactcaatg tctataggta ggtccacctt 60 atcgcgacac taggttaatg gataaatgtc ttttacttct ggtgtcattt ctgtgtgtat 120 tgtaggactc atcatgcctg ttttctcctt tcgttcttcg tttattatgt tagcatactt 180 tttacgtcag cgcaagg 197 <210> 1092 <211> 197 <212> DNA <213> Artificial Sequence <400> 1092 ctctacacgt ttctgtacat ctttagacaa tgcgtctaaa gacttttcta tcacgtgttg 60 aggtggttga ttgatagttc caaactcaat aaagtgcgcg cgccacgcaa cctcatcatc 120 aaagccactt tctacatatc catctttggc tttgctatag ataacatggt ctctcatatg 180 ctcacccata tatgaac 197 <210> 1093 <211> 196 <212> DNA <213> Artificial Sequence <400> 1093 tttctacata tccatctttg gctttgctat agataacatg gtctctcata tgctcaccca 60 tatatgaacc acgcttaccg ctcatttttg ctttactgtt agaccagtat ggtacgcgtt 120 tgctaaagtc ctcagcaacc tcaggcgcta tgtcgttcat tattttattt gcctcacggt 180 ctaagtcttt acctag 196 <210> 1094 <211> 196 <212> DNA <213> Artificial Sequence <400> 1094 tccgctgtac aatgacacgt gaccaaacgg gtaagaagtt cacttggaac tttgagcata 60 tccaatcaca caacggaatt aaaccagtta caaaaaaccc atttacctac aatgcacctg 120 tagcaaacaa agcttccgtt gttaaaacat ctagatggct actcaagtat aaagactcag 180 tagccacaag ggaggt 196 <210> 1095 <211> 196 <212> DNA <213> Artificial Sequence <400> 1095 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccagt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctgtgtg taaaaa 196 <210> 1096 <211> 196 <212> DNA <213> Artificial Sequence <400> 1096 atgagtaact cctccttacc tacaggcggt tctactgtac ctgtaacaat aacaggtgtc 60 acttttgcat ttcgccattt attaatcgtt acagtaatca tttatttttc ctccttatta 120 gacattattc ccataggaac atatcatttc ttataacaaa aatatcttct gacttagtat 180 cataatgcaa ctctac 196 <210> 1097 <211> 196 <212> DNA <213> Artificial Sequence <400> 1097 tgaatctacg tcacgcccaa cacgtagagt aatatctttc tcgtccccca tatcctctac 60 aatgttcagt gttttacttt ttaactgcat gttttcaaac tcaaagtcaa tggtaaactt 120 agcgcctcca aagtctgaaa taatactcct tagacgctcc actgctgttg tctcattatc 180 atagtttaaa gtacgt 196 <210> 1098 <211> 196 <212> DNA <213> Artificial Sequence <400> 1098 tcctcagcaa cctcaggcgc tatgtcgttc attattttat ttgcctcacg gtctaagtct 60 ttacctaggt caccaagcgc tttgtagatg tcactaaagt ctacataatt atcactcatt 120 ttaccacctc atttaaaacg tcctctttag aaacctcctt agcaatcaaa gtatcaaagt 180 ctttgctgta tgttcc 196 <210> 1099 <211> 196 <212> DNA <213> Artificial Sequence <400> 1099 ttaaaacgcc catctgggtc aacccacgag aacccactta atgtaatggg gttgtttgac 60 ccctctggtg taccacctaa tgctcgtatt gctgtagtta actcataaat gttacctgta 120 gttacgagtg aatctacgtc acgcccaaca cgtagagtaa tatctttctc gtcccccata 180 tcctctacaa tgttca 196 <210> 1100 <211> 196 <212> DNA <213> Artificial Sequence <400> 1100 taataaaggg ttacagtacc ttgaatatga agaacattta gactactcag aaattgagat 60 ttgtcacggt gagaaagtgg ggtaaatgaa atgacaccag aaaacgttga aaaagagtac 120 ggtgtgtacg ttgttggagg agacattatt gatatattag accatgtttt tccaagctat 180 gaagaagctt tagaac 196 <210> 1101 <211> 196 <212> DNA <213> Artificial Sequence <400> 1101 tgtattaatt gacggtgact cacctactga attagcacta tacgcgctta acgtagtaca 60 gcaaaatgat gataacgagg acttattaaa tgaagttgag aatataattg ataaactaga 120 ggaggaatta gtttgaaaac atatgagtta gtaaacaacg agacgacacc tttaccaatt 180 ggggcagtct tgtacg 196 <210> 1102 <211> 196 <212> DNA <213> Artificial Sequence <400> 1102 tgaaacagac tcaggtgaca taattgaatt agataaccct agcaagctgt ttaacgcact 60 tagggttgag tctaatggtt ttataccata tgtaagtaaa gtagctaaaa acagcaagac 120 agaccgtcta aaagacatac tagaagaaac taaaggagaa cgcgttgtta ttggctatca 180 atataaagaa acgtgt 196 <210> 1103 <211> 196 <212> DNA <213> Artificial Sequence <400> 1103 tgaaacagac tcaggtgaca taattgaatt agataaccct agcaagctgt ttaacgcact 60 tagggttgcg tctaatggtt ttataccata tgtaagtaaa gtagctaaaa acagcaagac 120 agaccgtata aaagacatac tagaagaaac taaaggagaa cgcgttgtta ttggctatca 180 atataaagaa acgtgt 196 <210> 1104 <211> 196 <212> DNA <213> Artificial Sequence <400> 1104 agtctaatac ctcaatttgg ttatcatata cccaccatag gtgaccatca atacttagtt 60 caagttggag cgtttgtccg tcaatttctt cagcgctatg agctactctg aacacctctc 120 caacgtattc cctgtcacgc tcgtaaccct cattcataaa aaattcagtt ggttcaggtt 180 taatcaagcg cacctt 196 <210> 1105 <211> 196 <212> DNA <213> Artificial Sequence <400> 1105 acaatattta gtaatttatg atattgaggt atttgagcaa gattttgtca tttgtgctaa 60 agatttgtgt agtggtaaac gttgggaaat tgtcaatgac ctagacaagg cgcgtaaatg 120 gtatttagaa gtacgtgaca gtctatttac tggttataac tctgctagtt atgataataa 180 tgtgctccgt ggttat 196 <210> 1106 <211> 196 <212> DNA <213> Artificial Sequence <400> 1106 ttgctgaatg cgtctattgt gacggaatat ttaactcctg ctggcaagta gttggttaat 60 aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa cactcgcatg 120 ttcccgtgtg aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct 180 ttcgagaaat cataat 196 <210> 1107 <211> 196 <212> DNA <213> Artificial Sequence <400> 1107 gtcaaagcca ttgagtattg caaacgtaca ggatggtcaa aatccatttt tacacacagc 60 ttacgcatgg agtagtgatg gaaaagagag gttcacactc caatacccaa atgataattt 120 agtattgtat tatgatttct cgaaagaccc cactattaat ggttggacag gaaatggtgc 180 gactatagaa tattca 196 <210> 1108 <211> 196 <212> DNA <213> Artificial Sequence <400> 1108 taataaaggg ttacagtacc ttgaatatga agaacattta gactactcag aaattgagat 60 ttgtcacgtt gagaaagtgg ggtaaatgaa atgacaccag aaaacgttga aaaagagtac 120 ggtgtgtccg ttgttggagg agacattatt gatatattag accatgtttt tccaagctat 180 gaagaagctt tagaac 196 <210> 1109 <211> 196 <212> DNA <213> Artificial Sequence <400> 1109 acaatattta gtaatttatg atattgaggt atttgagcaa gattttgtca tttgtgctaa 60 agatttgttt agtggtaaac gttgggaaat tgtcaatgac ctagacaagg cgcgtaaatg 120 gtatttataa gtacgtgaca gtctatttac tggttataac tctgctagtt atgataataa 180 tgtgctccgt ggttat 196 <210> 1110 <211> 196 <212> DNA <213> Artificial Sequence <400> 1110 ctattgtgac ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat 60 aatagactct tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat 120 attctatcgt cgcaccattt cctgtccaac cattaatagt ggggtctttc gagaaatcat 180 aattcaatac taaatt 196 <210> 1111 <211> 196 <212> DNA <213> Artificial Sequence <400> 1111 ataaccacgg agcacattat tatcataact agcagagtta taaccagtaa atagactgtc 60 acgtacttat aaataccatt tacgcgcctt gtctaggtca ttgacaattt cccaacgttt 120 accactacac aaatctttag cacaaatgac aaaatcttgc tcaaatacct caatatcata 180 aattactaaa tattgt 196 <210> 1112 <211> 196 <212> DNA <213> Artificial Sequence <400> 1112 gtagagttgc attatgatac taagtcagaa gatatttttg ttataagaaa tgatatgttc 60 ctatgggact aatgtctaat aaggaggaaa aataaatgat tactgtaacg attaataaat 120 ggcgaaatgc aaaagtgaca cctgttattg ttacaggtac agtagaaccg cctgtaggta 180 aggaggagtt actcat 196 <210> 1113 <211> 196 <212> DNA <213> Artificial Sequence <400> 1113 ctattgtgac ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat 60 aatagactat tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat 120 attctatcgt cgcaccattt cctgtccaac cattaatagt ggggtctttc gagaaatcat 180 aattcaatac taaatt 196 <210> 1114 <211> 196 <212> DNA <213> Artificial Sequence <400> 1114 tgaaacagac tcaggtgaca taattgaatt agataaccct agcaagctgt ttaacgcact 60 tagggttgag tctaatggtt ttataccata tgtaagtaaa gtagctaaaa acagcaagac 120 agaccgtata aaagacatac tagaagaaac taaaggagaa cgcgttgtta ttggctatca 180 atataaagaa acgtgt 196 <210> 1115 <211> 196 <212> DNA <213> Artificial Sequence <400> 1115 gttctaaagc ttcttcctag cttggaaaca catggtctaa tatatcaata ctgtctcctc 60 caacaacgga cacaccgtac tctttttcaa cgttttctgg tgtcatttca tttaccccac 120 tttctcaccg tgacaaatct caatttctga gtagtctaaa tgttcttcat attcaaggta 180 ctgtaaccct ttatta 196 <210> 1116 <211> 196 <212> DNA <213> Artificial Sequence <400> 1116 agtctaatac ctcaatttgg ttatcatata cccaccatag gtgaccatca atacttagtt 60 caagttggag cgtttgtccg tcaatttctt cagcgctatg agctactctg aacacctctc 120 caacgtagtc cctgtcacgc tcgtaaccct cattcataaa aaattcagtt ggttcaggtt 180 taatcaagcg cacctt 196 <210> 1117 <211> 196 <212> DNA <213> Artificial Sequence <400> 1117 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 60 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 120 gggggggtgg gggggggggg ggggggggtg gggggggggg gggggggggg gtgggggggg 180 gggggggggg gggggg 196 <210> 1118 <211> 195 <212> DNA <213> Artificial Sequence <400> 1118 tacctatgat tatgtatata ctagcgtgtg tttttatggc tattggtgcc tttttggtag 60 atataaccgt aggttttatg gtattaggtg gcgcttgttt ggctacaagt tttaagctat 120 caaaggactt agagcaggtt gataacatca acgataaagg agagagtcac taatgggaat 180 ttttatcaga aacaa 195 <210> 1119 <211> 195 <212> DNA <213> Artificial Sequence <400> 1119 tcaccttaat gcgtgtagcc gtaatttgtt gtttaaatac ctctggttct aaattataag 60 ggttcaagtc atcaatgaaa atcaactgtt tgtcaactag taacgcacta ttaaactcac 120 cttttgtgtt aaatgcgcgg ttagatggga gttctgtgta catttttcca aacaatggtg 180 agcctatgat tttgg 195 <210> 1120 <211> 195 <212> DNA <213> Artificial Sequence <400> 1120 ttaatatagg ttacttcttc tgtttcaagt tctccgtcct cattttcaac tggttcaagt 60 ttaccggatt ttactttgaa taagttaaca gctttatcac ccgttttcac agcaaacaca 120 cggtttactt tctgtgcgtc atgttcatta ccatcactat caacgtatac actcttgtca 180 aacgtccaac ctgtt 195 <210> 1121 <211> 195 <212> DNA <213> Artificial Sequence <400> 1121 attgaaaata attggcaaaa tacgtcttaa cgaaccatct gaggcgtcac gtactttaaa 60 tacatcatta ctagcacccg caaagtgtcc gccaaagcgc gcgtcatatt cagccttacc 120 cttttcagtc accttaatgc gtgtagccgt aatttgttgt ttaaatacct ctggttctaa 180 attataaggg ttcaa 195 <210> 1122 <211> 195 <212> DNA <213> Artificial Sequence <400> 1122 tataaacgcg tacagtgaag catactttta tgagttcgag gaaataaact ggtcagaacg 60 ttacgcaagc ggtgagtttg gttttggact gtaataaacg aacgaggcaa cccaactagg 120 gttgtctttt tcgtgttata atttataaag aagttataat tggaggaggt tcaccatgga 180 acgaattata tattt 195 <210> 1123 <211> 195 <212> DNA <213> Artificial Sequence <400> 1123 ttagagcagg ttgataacat caacgataaa ggagagagtc actaatggga atttttatca 60 gaaacaatcc acacgaagag cgggcaaatc tataccccgt agcaccatca ccaatggttg 120 tggactttgg tacttttatt acagggcaat cactagacga gattgaacat ttaaaaaatt 180 ctgacattta cacag 195 <210> 1124 <211> 195 <212> DNA <213> Artificial Sequence <400> 1124 cctcgtctgc ctcatcatcc ttaggttgtt catccttagg ttgctcgtca gggttaacct 60 cgtctgtgtg ttcgtcttgt gcctcacgaa tttccttgat taatttatcc gcctcatcta 120 atttaccttg tgcgataagt tcacgggctt ctagtaatcg tttatccatg tttcacactc 180 cttattatgt ttctt 195 <210> 1125 <211> 195 <212> DNA <213> Artificial Sequence <400> 1125 gaccatattg acccctatcc atacttgcgt aaatggggaa ttagtaaaga gcagtttgct 60 aaagacatta aaaatgggtt tggtggaaat agttccaata ctgacaacaa acctaaacca 120 caaccacaac cgtctaaacc aaaaatcaca gacacacgtg atttccctgt aggtagtaaa 180 gtaaaagtac gcgcc 195 <210> 1126 <211> 195 <212> DNA <213> Artificial Sequence <400> 1126 tctcaattaa tactttctct gtaggtgtca attcgttttc aggtagttcg tacaagactg 60 ccccaatggg taaaggtgtc gtctcgttgt ttactaactc atatgttttc aaactaattc 120 ctcctctagt ttatcaatta tattctcaac ttcatttaat aagtcctcgt tatcaacatt 180 ttgctgtact acgtt 195 <210> 1127 <211> 195 <212> DNA <213> Artificial Sequence <400> 1127 tattagttta tcaaaacccc aaccagttgt caagcattat ttttaaattt cttgtaaatg 60 ttcgtacgga atgagctgac gtataccatc aatcgttcta catggtatag ggtctctgtg 120 tttctctgtc tcaattaata ctttctctgt aggtgtcaat tcgttttcag gtagttcgta 180 caagactgcc ccaat 195 <210> 1128 <211> 195 <212> DNA <213> Artificial Sequence <400> 1128 cgtgggttat tcctatccct gaaaaagaat tgtttattgt tgactctcac gcgtgggtag 60 caacaacggg tggtggtatt gttcagaaag aggctaacga tagaacaccc tatagacaat 120 attccaacca ggggtattgt gaaatttctt cccgtcctga cggtcagtgt gattgggagg 180 atatgttaaa ttggg 195 <210> 1129 <211> 195 <212> DNA <213> Artificial Sequence <400> 1129 gggttacagt accttgaata tgaagaacat ttagactact cagaaattga gatttgtcac 60 gttgagaaag tggggtaaat gaaatgacac cagaaaacgt tgaaaaagag tacggtgtgt 120 ccgttgtggg aggagacatt attgatatat tagaccatgt ttttccaagc tatgaagaag 180 ctttagaaca tgcta 195 <210> 1130 <211> 195 <212> DNA <213> Artificial Sequence <400> 1130 tttcaacttc taactcatag taattaaggt caatttcatc taattgtaca ccttcaccaa 60 tctgctcatt ggaaatggta tagtattgag gggggttgtt tagacctgtt acatatgagt 120 catcaccatt aatataggtt acttcttctg tttcaagttc tccgtcctca ttttcaactg 180 gttcaagttt accgg 195 <210> 1131 <211> 195 <212> DNA <213> Artificial Sequence <400> 1131 ttttacacac agcttacgca tggagtagtg atggaaaaga gaggttcaca ctccaatacc 60 caaatgataa tttagtattg aattatgatt tctcgaaaga ccccactatt aatggttgga 120 caggaaaggg tgcgactata gaatattcaa acgggaacat gcgagtgttg tttaacgact 180 catcaactaa cagaa 195 <210> 1132 <211> 195 <212> DNA <213> Artificial Sequence <400> 1132 ggtctaaacc gttgtttgca tatacagcta gaatagaggt tcgttggttg cgtatagggt 60 accacgcatt gagttgcctg ttgtcacttt caaatcgttc aaagaatgag gtaagggact 120 catttatttt tgactgagtt acattcacat tggctaaatg tgggtgcatg gttttgaaca 180 tatcaaacgt aagcc 195 <210> 1133 <211> 195 <212> DNA <213> Artificial Sequence <400> 1133 tagcatgttc taaagcttct tcatagcttg gaaaaacatg gtctaatata tcaataatgt 60 ctcctccaac aacgtacaca ccgtactctt tttcaacgtt ttctggtgtc atttcattta 120 ccccactgtc tcaacgtgac aaatctcaat ttctgagtag tctaaatgtt cttcatattc 180 aaggtactgt aaccc 195 <210> 1134 <211> 195 <212> DNA <213> Artificial Sequence <400> 1134 gctctaaacc gttgagtgca tatacaccta gaatagaggt tcgttggttg cgtataggga 60 accacgcttt gagttgcctg tagtcacggt caaatcgtac aaagaatgag gtaagggact 120 catttatatt tgactgagtt acattcacat tggctaaatg tgggtgcatg gatttgaaca 180 tatcaaacgt aagcc 195 <210> 1135 <211> 195 <212> DNA <213> Artificial Sequence <400> 1135 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 60 aacagaagag tctattatag caatgactaa ttaaccaact acttgccagc aggagttaaa 120 tataccgaca caatagacgc attcagcaac aataatgggt taattagcgt aggtaatttt 180 gacgctctca gtaca 195 <210> 1136 <211> 195 <212> DNA <213> Artificial Sequence <400> 1136 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 60 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 120 tattccgaca caatagacgc attcagcaac aataatgggt taattagggt aggtaatttt 180 gacgctctca gtaca 195 <210> 1137 <211> 195 <212> DNA <213> Artificial Sequence <400> 1137 tagcatgttc taaagcttct tcatagcttg gaaaaacatg gtctaatata tcaataatgt 60 ctcctcccac aacgtacaca ccgtactctt tttcaacgtt ttctggtgtc atttcattta 120 ccccactgtc tcaacgtgac aaatctcaat ttctgagtag tctaaatgtt cttcatattc 180 aaggtactgt aaccc 195 <210> 1138 <211> 195 <212> DNA <213> Artificial Sequence <400> 1138 ggtctaaacc gttgtttgca tatacagcta gaatagaggt tcgttggttg cgtatagggt 60 accacgcatt gagttgcctg tagtcactgt caaatcgttc aaagaatgag gtaagggact 120 catttatatt tgactgagtt acattcacat tggctaaatg tgggtgcatg gttttgaaca 180 tatcaaacgt aagcc 195 <210> 1139 <211> 194 <212> DNA <213> Artificial Sequence <400> 1139 atgagaaagc tgagtttatt agatggtgtg tacaggagta tgctgaacta ttgaaacgca 60 gagaggacgt taccgcagac gagtttgtgt ggacgctatc tgatgaggct aaggaaatgc 120 gtgaggacct agtacgtagt aaaacacctg ttattgattt agcctttaat agtggactat 180 ttgagcacac gggt 194 <210> 1140 <211> 194 <212> DNA <213> Artificial Sequence <400> 1140 cgtatctcag agcctctcag agcgttttag agcatgtttg tttttgagcg taaaaaagag 60 agggttattt ccctctcaat ttgtttctat tactgtttgg atgttcttgt ttgttgtgac 120 aagaaaatca aatactttct aaataattca tatctaacct atgttcccat ccctcagagg 180 ttcgtatctc cgtg 194 <210> 1141 <211> 194 <212> DNA <213> Artificial Sequence <400> 1141 gcgtgtgcgt gcagtacatt gtaagcaaac attagacgag cgtgtatcat aatgtctaat 60 tctttaggct cgtccataat gcgggcacgc aattcatcta aaacattgtc taactccgcg 120 tcatgtactt ctaatacctc tgctaatttt gtcatattat ttttcctcct catagtctaa 180 tacctcaatt tggt 194 <210> 1142 <211> 194 <212> DNA <213> Artificial Sequence <400> 1142 accaatttaa ggggtttcct ctcaaagcgc gtactaaaat tcccgcgata aaagagtggc 60 aagctcaaga gtgttacaat acattaggta aaatatgaaa catgaataaa ggggtcttat 120 gtggggaaca aaacaaatta ttagtagtag actgtgacgt aaaaggtaaa gcaaacggaa 180 tacactcttt tact 194 <210> 1143 <211> 194 <212> DNA <213> Artificial Sequence <400> 1143 gtatttggca atcaccttac gcgctacatt agtaaggtat ttatacacac ccgctgtacc 60 tacagacgta tctaggctcc cgctctcaaa cgcctcagta acacgtgacg taagagcgct 120 agtagctgtc ttaatcattc cacgggcaac gtctagagga tattttatga gacctgaggt 180 gtctactacg ctag 194 <210> 1144 <211> 194 <212> DNA <213> Artificial Sequence <400> 1144 tgtctactgt aggtgtatta ccgtctgtcc actgtgtagc accctcatta gttgcctcaa 60 ttttagcgcg ccaaattgta atatcaggta agtcccctgt tgcgtcagag tagaaattaa 120 accccatctc tgttgaaccc atggtgtaag ttggttcaaa gctaatgtac ttactctcat 180 tgggatatat tgtt 194 <210> 1145 <211> 194 <212> DNA <213> Artificial Sequence <400> 1145 tatcttgagt gctatatccg tttagttcat aaatgaggtc gtccatggct aacgcgttgc 60 catggacctc ctcctctaga actctgttaa acagcatatt taactcatca tcaaacccat 120 taccgtttaa taccttgtta atatactccg ttttaaattg ctctaacata attatccccc 180 ttagaataaa tctt 194 <210> 1146 <211> 194 <212> DNA <213> Artificial Sequence <400> 1146 tctagtaagt aggtatggta ctacagtaga tagtgcgatt ccgtcaggcg catggataaa 60 catctcgtgc gtatatgcgg gtcaagattt attctaaggg ggataattat gttagagcaa 120 tttaaaacgg agtatattaa caaggtatta aacggtaatg ggtttgatga tgagttaaat 180 atgctgttta acag 194 <210> 1147 <211> 194 <212> DNA <213> Artificial Sequence <400> 1147 caatggcaag tggtaaaaca ttgtttggta aagaggtaat tgtacttcct gacgctatct 60 ttaaaatcga cacaaatgat aaactattat tcattggtga cttagaacaa gctattactt 120 tgttcaaacg tactgaaatg acggtacgtt ggcaagacca caatgtctac ggtgaaatgt 180 tagcgggtgc catc 194 <210> 1148 <211> 194 <212> DNA <213> Artificial Sequence <400> 1148 gtggtaaaac attgtttggt aaagaggtaa ttgtacttcc tgacgctatc tttaaaaacg 60 acacaaatga taaactatta ttcattggtg acttagaaca agctattact ttgttcaaac 120 gtactgacat gacggtacgt tggcaagacc acaatgtcta cggtgaaatg ttagcgggtg 180 ccatccgttt tgac 194 <210> 1149 <211> 194 <212> DNA <213> Artificial Sequence <400> 1149 tacatatagt ccctcatgtc ctcttttacc attttacgcg ttattctact tctatcatct 60 gtgttgtatc tgtttgctag aagaataccg tccgtgaaga gtttcaattc aacaaggtca 120 ccctcatgac ccgtgtgctc aaatagtcca ctattaaagg ctaaatcaat aacaggtgtt 180 ttactacgta ctag 194 <210> 1150 <211> 194 <212> DNA <213> Artificial Sequence <400> 1150 tctgttgaac ccatggtgta agttggttca aagctaatgt acttactctc attgggatat 60 attgttgtac ccactcccat tctgtttgaa atagaaatag gtttatcacc gttgtttttt 120 acatatatac tatgcgtgta gttttgtcct atgatgtact gtgttccttt aatttctaac 180 acacctatga gatt 194 <210> 1151 <211> 194 <212> DNA <213> Artificial Sequence <400> 1151 tccatggcaa cgcgttagcc atggacgacc tcatttatga actaaacgga tatagcactc 60 aagataccgc agtagacacg ttacagaacc aagttgacta catgagtaaa atgataaata 120 gactagcata caatcaaagt taggagcggg aacgaatgcc aatgaatgag gacaacttta 180 tcaaaatgca atta 194 <210> 1152 <211> 194 <212> DNA <213> Artificial Sequence <400> 1152 gggttacgag cgtgacaggg aatacgttgg agaggtgttc agagtagctc atagcgctga 60 agaaattgac ggacaaacgc accaacttga actaagtatt gatggtcacc tatggtgggt 120 atatgatcac caaattgagg tattagacta tgaggaggaa aaataatatg acaaaattag 180 cagaggtatt agaa 194 <210> 1153 <211> 194 <212> DNA <213> Artificial Sequence <400> 1153 agcgcaggtc aatatgtcat taaccaacct ctaccagttt gggctagacc attgaataac 60 gtaacactca ttcatcaagg ttctggaatg aacaggctac tactagaagt gcgcaaggat 120 ggtgcaagtc tagtaagtag gtatggtact acagtagata gtgcgattcc gtcaggcgca 180 tggataaaca tctc 194 <210> 1154 <211> 194 <212> DNA <213> Artificial Sequence <400> 1154 cgtatctcag agcctctcag agcgttttag agcatgtttg tttttgagcg taaaaaagag 60 agggttcttt ccctctcaat ttgtttctat tactgtttgg atgttcttgt ttgttgtgac 120 aagaaaatca aatactttct aaataattca tatctaacct atgttcccat ccctcagagg 180 ttcgtatctc cgtg 194 <210> 1155 <211> 194 <212> DNA <213> Artificial Sequence <400> 1155 caatggcaag tggtaaaaca ttgtttggta aagaggtaat tgtacttcct gacgctatct 60 ttaaaatcga cacaaatgat aaactattat tcattggtga cttagaacaa gctattactt 120 tgttcaatcg tactgaaatg acggtacgtt ggcaagacca caatgtctac ggtgaaatgt 180 tagcgggtgc catc 194 <210> 1156 <211> 194 <212> DNA <213> Artificial Sequence <400> 1156 tcttaatcat tccacgggca acgtctagag gatattttat gagacctgag gtgtctacta 60 cgctagtgaa tactttttca actaatttgc ttgggttagt tgcgtagtcc caaacgtcac 120 caacaacact gctaacctta tcaaacgcac ttttagccat gtttttggca ccgttccaga 180 tgtttattac gcct 194 <210> 1157 <211> 193 <212> DNA <213> Artificial Sequence <400> 1157 tttagcatac tacagtaaaa tggaaaaggt tgaaaaaggt gagttacaaa tgaatgagat 60 tgaggattta gatgatatgc taaacttagt tctctccatt ttctcaaaca caaaacttac 120 ttatgatatg ttagtggata acgtagcctt tgaggactta ttaccattag tacagggagt 180 ctttgaacaa gtc 193 <210> 1158 <211> 193 <212> DNA <213> Artificial Sequence <400> 1158 gtgaaattac actagagaac tcacaaatca aaaacaatat aaaacagtac agtagcacag 60 gagtgattaa aaacgcacat cgtcaaatta tggcagcaaa ctatatactc atggctacaa 120 ctaatgaagc aggtaacaca aactacaatc aattatatct agaccctgac gcactaaatc 180 tacaaacatt cag 193 <210> 1159 <211> 193 <212> DNA <213> Artificial Sequence <400> 1159 tttaacacaa aaggtgagtt taatagtgcg ttactagttg acaaacagtt gattttcatt 60 gatgaattga acccttataa tttagaacca gaggtattta aacaacaaat tacggctaca 120 cgcattatgg tgaatgaaaa gggtaaggct gaatatgacg cgcgctttgg cggacacttt 180 gcgggtgcta gta 193 <210> 1160 <211> 193 <212> DNA <213> Artificial Sequence <400> 1160 tttcccttag catttcgttt tctctaatga ggttattacg ttcacgaagt aatagaactt 60 tatccacttt atcaaggttc tcaggcgttt cccatctatt ggacattagg ttcactctcc 120 ttataagtga aatcacttgc gaaaaatgaa gcgtaacgtt tatcattaat gtctgtaggg 180 aatacccaag tta 193 <210> 1161 <211> 193 <212> DNA <213> Artificial Sequence <400> 1161 acatagcgcg tgagcgtttg gctttgtcta gtggaataac catttcaggt ttattaccct 60 ctccccccat agctaaatgt tctcgtgtga tgagtccacc gttagcataa ccagtaccgc 120 gccatccgcg cgttagagaa ccgtaacggg ctaaagtata tctaattgac gctaaaatgt 180 ttgataatgg gtc 193 <210> 1162 <211> 193 <212> DNA <213> Artificial Sequence <400> 1162 aatacaatac ctacgcgctc agaaatgtca tcacagaacg cgtctgtaat acgttcagcc 60 tcctcctcat gaggaatgta ggcgtgacag tctgtgttgc tctgtaacat ggtaacatgg 120 tccctaattc cctcgtagaa gtcagccata attaattgcc caatcacaca tgttagaaat 180 tgaaaacgtg ggt 193 <210> 1163 <211> 193 <212> DNA <213> Artificial Sequence <400> 1163 tagctgacta agttctgcgt tttcctcaat aagctcctca ttgtcctcaa ttagttcagc 60 tatgcgttga cttttatggt caacctcatc tgctaactcg tctacctcta aacgagcgtc 120 taacaacatt tcccttagca tttcgttttc tctaatgagg ttattacgtt cacgaagtaa 180 tagaacttta tcc 193 <210> 1164 <211> 193 <212> DNA <213> Artificial Sequence <400> 1164 cctaatacat cgtcaatacg gtctgaaatc gtgtctctat caaacccata ctcatctacg 60 agtttagcac ctaaagcgct tgccataata atgttgaaag caagtttttc ctcatctact 120 tttttacagt atttcaactt atcaaaatca aactttagtt cctgtaagac gttctcaaac 180 gctttgtgtg ttt 193 <210> 1165 <211> 193 <212> DNA <213> Artificial Sequence <400> 1165 ctgaatgttt gtagatttag tgcgtcaggg tctagatata attgattgta gtttgtgtta 60 cctgcgtcat tagttgtagc catgagtata tagtttgctg ccataatttg acgatgtgcg 120 tttttaaaca ctcctgtgct actgtactgt tttatattgt ttttgatttg tgagttctct 180 agtgtaattt cac 193 <210> 1166 <211> 193 <212> DNA <213> Artificial Sequence <400> 1166 ttgtaacagt gcgtttgttt gttgttgctg tacaatcaat tgagcaatta gctcatcatt 60 agaaccctga ccagctacca cggttgtttg tgatacacct aaccgctttt gtgcctcagc 120 tagtagagac atagcgcgtg agcgtttggc tttgtctagt ggaataacca tttcaggttt 180 attaccctct ccc 193 <210> 1167 <211> 193 <212> DNA <213> Artificial Sequence <400> 1167 cgtctccgtt gaacacgggg tactctttgc caaacctcca atttacacta ttaaactcac 60 ctgtgtaaat taaaacatct ccgactttta gttcattaac tttaaccatt gttttcctcc 120 ttaatataca acactaacaa tgtagtacgg ttgtattact acattcacgg gcacagagct 180 tagtagcata atc 193 <210> 1168 <211> 193 <212> DNA <213> Artificial Sequence <400> 1168 caacactaac aatgtagtac ggttgtatta ctacattcac gggcacagag cttagtagca 60 taatcagaaa aacctctcct gtttgcatac gttcaataac aaactctggg gaacccttat 120 atgtgtaaga gcgtccgttg accatgcaga tggtaatggt acgggtctca ttgctttcat 180 taataacagg tgt 193 <210> 1169 <211> 193 <212> DNA <213> Artificial Sequence <400> 1169 tttgatgttc tttctcgtaa agaacatgag gataataagc acctagagaa agaactctta 60 gataaacgtc ttgaggcgaa aaatacagat gaaacagaga atacattgaa cgaagtaaag 120 ttacaaaagt ttgtgttagt acctggggta aaattgccta ttaatacatt gtttggtgcc 180 acaggtgcag agt 193 <210> 1170 <211> 193 <212> DNA <213> Artificial Sequence <400> 1170 catttcaccg tagacattgt ggtcttgcca acgtaccgtc atttcagtac gtttgaacaa 60 agtaagagct tgttctaagt caccaatgaa taatagttta tcatttgtgt cgtttttaaa 120 gatagcgtca ggaagtacaa ttacctcttt accaaacaat gttttaccac ttgccattgc 180 tacgtttggt tga 193 <210> 1171 <211> 193 <212> DNA <213> Artificial Sequence <400> 1171 tatgatataa tattaataga acataacata ttaggaggaa ttataatgat taaattagaa 60 ctaaaagtaa aaggtaaaaa acaaacattt acagcggaga aagtaactgt acgaacaatg 120 cgcgagaatt tagcatacta cagtaaaatg gaaaaggttg aaaaaggtga gttacaaatg 180 aatgagattg agg 193 <210> 1172 <211> 193 <212> DNA <213> Artificial Sequence <400> 1172 gtatacgtca gctcattccg tacgaacatt tacaagaaat ttaaaaataa tgcttgacaa 60 ctggttgggg ttttgataaa ctaataaatg tattaaaaca ttaggaggaa aacagatgaa 120 taaagaataa acacacaaag cgtttgagaa cgtcttacag gaactaaagt ttgattttga 180 taagttgaaa tac 193 <210> 1173 <211> 193 <212> DNA <213> Artificial Sequence <400> 1173 acccacgttt tcaatttcta acatgtgtga ttgggcaatt aattatggct gacttctacg 60 agggacttag ggaccatgtt accatgttac agagcaacac agactgtcac gcctacattc 120 ctcatgagga ggaggctgaa cgtattacag acgcgttctg tgatgacatt tctgagcgcg 180 taggtattgt att 193 <210> 1174 <211> 193 <212> DNA <213> Artificial Sequence <400> 1174 ctgaatgttt gtagatttag tgcgtcaggg tctagatata attgattgta gtttgtgtta 60 cctgcgtcat tagttgtagc catgagtata tagtttgctg ccataatttg acgatgtgcg 120 tttttaatca ctcctgtgct actgtactgt tttatattgt ttttgatttg tgagttctct 180 agtgtaattt cac 193 <210> 1175 <211> 193 <212> DNA <213> Artificial Sequence <400> 1175 ttactttgtt caaacgtact gaaatgacgg tacgttggca agaccacaat gtctacggtg 60 aaatggtagc gggtgccatc cgttttgacg tagtagctac agacacaaag gcgggcttaa 120 tgttcaaatt aggagctatt cctaacaacg tttctacggt aacagtagca aatgcgtctg 180 agttccctag tgg 193 <210> 1176 <211> 192 <212> DNA <213> Artificial Sequence <400> 1176 tttacacagg tgagtttaat agtgtaaatt ggaggtttgg caaagagtac cccgtgttca 60 acggagacgg tcaactatat gttttgacag atatgcataa tatgtatttt atttttgacc 120 atgaggacta tattgagtca aaatttgaac tgaaagaaaa ggaggctgta aaggaaacgg 180 gaattgtaca ca 192 <210> 1177 <211> 192 <212> DNA <213> Artificial Sequence <400> 1177 ttgactctaa tgccatgttt tttacctcct ctaatactct acagaacaat aataggtata 60 tacatttgat ggtcctgcat ttactgtgat tgttgttcct gttgctgtcc atgatgtgtc 120 taatacgatt gaggcgtcat atctacgcca tacaaacgaa gtaaaattat cagtaatgtc 180 atccttgcct tt 192 <210> 1178 <211> 192 <212> DNA <213> Artificial Sequence <400> 1178 atgagtaaaa tgataaatag actagcatac aatcaaagtt aggagcggga acgaatgcca 60 atgactgagg acaactttat caaaatgcaa ttaaccatgg agcgtattga cgcacgttta 120 gaggacgtga gagagattaa aaaagagctg tctggtgccc gtcaacaaat cgcggaccta 180 gacaaacgtc tt 192 <210> 1179 <211> 192 <212> DNA <213> Artificial Sequence <400> 1179 tctcctggtc tatatccact tgttacgcgc ataccagggt atttggcaat caccttacgc 60 gctacattag taaggtattt atacacaccc gctgtaccta cagacgtatc taggctcccg 120 ctctcaatcg cctcagtaac acgtgacgta agagcgctag tagctttctt aatcattcca 180 cgggcaacgt ct 192 <210> 1180 <211> 192 <212> DNA <213> Artificial Sequence <400> 1180 aaattcatga tttaattaaa gttgaaacaa ccatgttgga ccctgcgtca ggttggcaaa 60 gatagagtga tgttatggga tacactaaca cacctacagc cacgcgagta ggtagaacgg 120 ttcaaatagc aggtgcgttt aaacccataa accaacttag cgcaggtcaa tatgtcatta 180 accaacctct ac 192 <210> 1181 <211> 192 <212> DNA <213> Artificial Sequence <400> 1181 ctcctcaggt tgtaagtaaa cgtcaaaaac ctcctccaat cagcttacca ccgcacattg 60 ggcaatagtg aatctcaaac tgagcggtat aaccttggtt gtcaacctca gttgtgactg 120 tcatagtgtt cccgtttata aacacctcag tcatgtcagt cctcccactc cataagtaat 180 ctgaggaaaa ta 192 <210> 1182 <211> 192 <212> DNA <213> Artificial Sequence <400> 1182 tttgcctctc catgttgagg tgtctgcata atcataaaaa ctgagaaaga aatgtaggag 60 tggttcgttt acgcgcgcgt tagagccatc cattgggaaa attttcaaac gcacgtacat 120 tttggctgtg tgtacaattc ccgtttcctt tacagcctcc ttttctttca gttcaaattt 180 tgactcaata ta 192 <210> 1183 <211> 192 <212> DNA <213> Artificial Sequence <400> 1183 atgagtaaaa tgataaatag actagcatac aatcaaagtt aggagcggga acgaatgcca 60 atgaatgagg acaactttat caaaatgcaa ttaaccatgg agcgtattga cgcacgttta 120 gaggacggga gagagattaa aaaagagctg tctggtgccc gtcaacaaat cgcggaccta 180 gacaaacgtc tt 192 <210> 1184 <211> 192 <212> DNA <213> Artificial Sequence <400> 1184 cgcctcagta acacgtgacg taagagcgct agtagctttc ttaatcattc cacgggcaac 60 gtctcgagga tattttatga gacctgaggt gtctactacg ctagagaata ctttttcaac 120 taatttgctt gggttagttg cgtagtccca aacgtcacca acaacactgc taaccttatc 180 aaacgcactt tt 192 <210> 1185 <211> 192 <212> DNA <213> Artificial Sequence <400> 1185 tattttcctc agattactta tggagtggga ggactgacat gactgaggtg tttataaacg 60 ggaaaactat gacagtcaca actgaggttg acaaccaagg ttataccgct cagtttgaga 120 ttcactagtg cccaatgtgc ggtggtaagc tgattggagg aggtttttga cgtttactta 180 caacctgagg ag 192 <210> 1186 <211> 192 <212> DNA <213> Artificial Sequence <400> 1186 aaattcatga tttaattaaa gttgaaacaa ccatgttgga ccctgcgtca ggttggcaaa 60 gatatagtga tgttatggga tacactaaca cacctacagc cacgcgagta ggtagaacgg 120 ttcaaatcgc aggtgcgttt aaacccataa accaacttag cgcaggtcaa tatgtcatta 180 accaacctct ac 192 <210> 1187 <211> 192 <212> DNA <213> Artificial Sequence <400> 1187 gctacgttat ccactaacat atcataagta agttttgtgt ttgagaaaat ggagagaact 60 aagtttagca tatcatctaa aacctcaatc tcattcattt gtaactcacc tttttcaacc 120 ttttccaatt tactgtagta tgctaaaatc tcgcgcattg ttcgtacagt tactttctcc 180 gctgtaaatg tt 192 <210> 1188 <211> 192 <212> DNA <213> Artificial Sequence <400> 1188 gcccctgcgg ttataccctc aaatttatac gttgaaggtg tgtcaccttg ttttattgtt 60 tgccatgtac tgagagcgtc aaaattacct accctaatta acccattatt gttgctgaat 120 gcgtctagtg tgacggaata tttaactcct gctggcaagt agttggttaa taagtcattg 180 ctataataga ct 192 <210> 1189 <211> 192 <212> DNA <213> Artificial Sequence <400> 1189 ttgactctaa tgccatgttt tttacctcct ctaataatct acagaacaat aatatgtata 60 tacaattgat tgtcctgcat ttactgtgat tgtttttcct gttgctgtcc atgatgtgtc 120 taatacgttt gaggcgtcat atctacgcca tacaaacgaa gtaaaattat cagtaatgtc 180 atccttgcct tt 192 <210> 1190 <211> 192 <212> DNA <213> Artificial Sequence <400> 1190 gctacgttat ccactaacat atcataagta agttttgtgt ttgagaaaat ggagagaact 60 aagtatagca tatcatctaa aacctcaatc tcattcattt gtaactcacc tttttcaacc 120 ttttccattt tactgtagta tgctaaaatc tcgcgcattg ttcgtacagt tactttctcc 180 gctgtaaatg tt 192 <210> 1191 <211> 192 <212> DNA <213> Artificial Sequence <400> 1191 attgagaaaa atagactatg gcaagcggtc aacttcttta ctgacccact aagtgaaaaa 60 gcattatgtg agttcatagg gtcatgcgtc tatgagaaca aacctgaggc tgttcatgct 120 caaattggtg tctcacgcgg tacacgcaac ggaggaaatg gaaagtctat tctaatgacc 180 aaaatcatag gc 192 <210> 1192 <211> 192 <212> DNA <213> Artificial Sequence <400> 1192 gcctatgatt ttggtcatta gaatagactt tccatttcct ccgttgcgtg taccgcgtga 60 gacaacaatt tgagcatgaa cagcctcagg tttgttctca tagacgcatg accctatgaa 120 ctcacatcat gctttttcac ttagtgggtc agtaaagaag ttgaccgctt gccatagtct 180 atttttctca at 192 <210> 1193 <211> 192 <212> DNA <213> Artificial Sequence <400> 1193 agtaaaagag tgtattccgt ttgctttacc ttttacgtca cagtctacta ctaataattt 60 gtttagttcc ccacataaga cccctttatt catgtttctt attttaccta atgttttgta 120 actctcttga gcttgccact cttttatcgc gggaatttta gtacgcgctt tgagaggaaa 180 ccccttaaat tg 192 <210> 1194 <211> 192 <212> DNA <213> Artificial Sequence <400> 1194 gtagaggttg gttaatgaca tattgacctg cgctaagttg gtttatgggt ttaaacgcac 60 ctgcgatttg aaccgttcta cctactcgcg tggctgtagg tgtgttagtg tatcccataa 120 catcactcta tctttgccaa cctgacgcag ggtccaacat ggttgtttca actttaatta 180 aatcatgaat tt 192 <210> 1195 <211> 192 <212> DNA <213> Artificial Sequence <400> 1195 atgagtaaaa tgataaatag actagcatac aatcaaagtt aggagcggga acgaatgcca 60 atgactgagg acaactttat caaaatgcaa ttaaccatgg agcgtattga cgcacgttta 120 gaggacggga gagagattaa aaaagagctg tctggtgccc gtcaacaaat cgcggaccta 180 gacaaacgtc tt 192 <210> 1196 <211> 192 <212> DNA <213> Artificial Sequence <400> 1196 tattttcctc agattactta tggagtggga ggactgacat gactgaggtg tttataaacg 60 ggaacactat gacagtcaca actgaggttg acaaccaagg ttataccgct cagtttgaga 120 ttcactagtg cccaatgtgc ggtggtaagc tgattggagg aggtttttga cgtttactta 180 caacctgagg ag 192 <210> 1197 <211> 192 <212> DNA <213> Artificial Sequence <400> 1197 aacatttaca gcggagaaag taactgtacg aacaatgcgc gagattttag catactacag 60 taaattggaa aaggttgaaa aaggtgagtt acaaatgaat gagattgagg ttttagatga 120 tatgctatac ttagttctct ccattttctc aaacacaaaa cttacttatg atatgttagt 180 ggataacgta gc 192 <210> 1198 <211> 192 <212> DNA <213> Artificial Sequence <400> 1198 gcctatgatt ttggtcatta gaatagactt tccatttcct ccgttgcgtg taccgcgtga 60 gacaccaatt tgagcatgaa cagcctcagg tttgttctca tagacgcatg accctatgaa 120 ctcacatcat gctttttcac ttagtgggtc agtaaagaag ttgaccgctt gccatagtct 180 atttttctca at 192 <210> 1199 <211> 192 <212> DNA <213> Artificial Sequence <400> 1199 aaaggcaagg atgacattac tgataatttt acttcgtttg tatggcgtag atatgacgcc 60 tcaatcgtat tagacacatc atggacagca acaggaaaaa caatcacagt aaatgcagga 120 caatcaattg tatatacata ttattgttct gtagattatt agaggaggta aaaaacatgg 180 cattagagtc aa 192 <210> 1200 <211> 191 <212> DNA <213> Artificial Sequence <400> 1200 catcattcgt aaaatcagta attttaatca ctgttttatc tttatataac ctagcgacac 60 tcaaggtagc accatgttta tctttcaaac tatattcaag tccctcatta acatagtcac 120 gttcaaaacg gtcatagtag aaccattcat caataccatc aacctgcacg aaaaggctgc 180 ctactccaac a 191 <210> 1201 <211> 191 <212> DNA <213> Artificial Sequence <400> 1201 caattattct aggtgttatt ttggcaattt cattgatgtt aaatgtgcgt tatagtgtag 60 agcgcaaata cttagtcgcc atcatggagg cacaaagtaa gtcaattact gagcttacga 120 ctgtcaatgg tggtacaaag tatgagaaac gttaatacga aacatgaacg gtttgaaccc 180 atggacgagc c 191 <210> 1202 <211> 191 <212> DNA <213> Artificial Sequence <400> 1202 ctcacgcgtg ggtagcaaca acgggtggtg gtattgttca gaaagaggct aacgatagaa 60 caccctatag acaatattcc aaacaggggt attgtgaaat ttcttcccgt cctgacggtc 120 agtgtgagtg ggaggatatg ttaaattggg ttttggcgtt tattgagaca aacaatttag 180 acgtacaagg t 191 <210> 1203 <211> 191 <212> DNA <213> Artificial Sequence <400> 1203 cgtcctcata cccgtctgct agtcttgtgg taattaattg agactgtgca gggtcataac 60 aaataccttg tacgtctaaa ttgtttgtct caataaacgc caaaacccaa tttaacatat 120 cctcccactc acactgaccg tcaggacggg aagaaatttc acaatacccc tgtttggaat 180 attgtctata g 191 <210> 1204 <211> 191 <212> DNA <213> Artificial Sequence <400> 1204 cttcattagt tgtagccatg agtatatagt ttgctgccat aatttgacga tgtgcgtttt 60 taaacactcc tgtgctactg tactgtttta tattgttttt gatttgtgag ttctctagtg 120 taatttctcc tgagccagtt gagttatctg aatatttcac attgtaaggg tttctgatgg 180 tactacctac a 191 <210> 1205 <211> 191 <212> DNA <213> Artificial Sequence <400> 1205 aacaatcatg tcatcatcca cattaataat gtaacccatg ttagaaacgc tgtacatatc 60 aaaaggctcg tccatgggtt caaaccgttc atgtttcgta ttaacgtttc tcatactttg 120 taccaccatt gacagtcgta agctcagtaa ttgacttact ttgtgcctcc atgatggcga 180 ctaagtattt g 191 <210> 1206 <211> 191 <212> DNA <213> Artificial Sequence <400> 1206 ttgacagtcg taagctcagt aattgactta ctttgtgcct ccatgatggc gactaagtat 60 ttgagctcta cactataacg cacatttaac atcaatgaaa ttgccaaaat aacacctaga 120 ataattgtac ccattataaa cacttccttt tctaattata ttctaataat accacagaat 180 ggagcacttg t 191 <210> 1207 <211> 191 <212> DNA <213> Artificial Sequence <400> 1207 tgaccaaacg ggtaagaagt tcacttggaa ctttgagcat atccaatcaa acaacggaat 60 taaaccagtt acaaaaaacc catttaccta caatgcacct gtagcaaaca aagcttccgt 120 tgttaaatca tctagatggc tactcaagta taaagactca gtagccacaa gggaggtagt 180 ggataaggta a 191 <210> 1208 <211> 191 <212> DNA <213> Artificial Sequence <400> 1208 ctatagacaa tattccaaac aggggtattg tgaaatttct tcccgtcctg acggtcagtg 60 tgattgggag gatatgttaa attgggtttt ggcgtttatt gagacaaaca atttagacgt 120 acaaggtctt tgttatgacc ctgcacagtc tcaattaatt accacaagac tagcagacgg 180 gtatgaggac g 191 <210> 1209 <211> 191 <212> DNA <213> Artificial Sequence <400> 1209 caattattct aggtgttatt ttggcaattt cattgatgtt aaatgtgcgt tatagtgtag 60 agctcaaata cttagtcgcc atcatggagg cacaaagtaa gtcaattact gagcttacga 120 ctgtcaaagg tggtacaaag tatgagaaac gttaatacga aacatgaacg gtttgaaccc 180 atggacgagc c 191 <210> 1210 <211> 191 <212> DNA <213> Artificial Sequence <400> 1210 tttaacaacg gaagctttgt ttgctacagg tgcattgtag gtaaatgggt tttttgtaac 60 tggattaatt ccgttgtttg attggatatg ctcaaagttc caagtgaact tcttacccgt 120 ttggtcacgt gtcattgtac agcggaacca agatgatttg tacttagtta cgtctgtctt 180 gatagatttt a 191 <210> 1211 <211> 191 <212> DNA <213> Artificial Sequence <400> 1211 atattgtatc agacaatgtt attgctgaaa acgggatgtt taaaaaagtt agtggggttg 60 agattgtagg tagtaccatc agaaaccctt acaatgtgaa atattcagat aactcaactg 120 gctcaggaga aattacacta gagaactcac aaatcaaaaa caatataaaa cagtacagta 180 gcacaggagt g 191 <210> 1212 <211> 191 <212> DNA <213> Artificial Sequence <400> 1212 ttaccttatc cactacctcc cttgtggcta ctgagtcttt atacttgagt agccatctag 60 atgttttaac aacggaagct ttgtttgcta caggtgcatt gtaggtaaat gggttttttg 120 taactggatt aattccgttg tttgattgga tatgctcaaa gttccaagtg aacttcttac 180 ccgtttggtc a 191 <210> 1213 <211> 191 <212> DNA <213> Artificial Sequence <400> 1213 ctatagacaa tattccaaac aggggtattg tgaaatttct tcccgtcctg acggtcagtg 60 tgagtgggag gatatgttaa attgggtttt ggcgtttatt gagacaaaca atttagacgt 120 acaaggtctt tgttatgacc ctgcacagtc tcaattaatt accacaagac tagcagacgg 180 gtatgaggac g 191 <210> 1214 <211> 191 <212> DNA <213> Artificial Sequence <400> 1214 taccacgctt tgagttgcct gtagtcactg tcaaatcgtt caaagaatga ggtaagggac 60 tcagttattt ttgactgagt tacattcaca ttggctaaat gtgggtgcat ggttttgaac 120 atatcaatcg taagccacgt aggagcctca tagccctctc taaatcgttc aaaggtaact 180 tgtacctcat c 191 <210> 1215 <211> 191 <212> DNA <213> Artificial Sequence <400> 1215 cttcattagt tgtagccatg agtatatagt ttgctgccat aatttgacga tgtgcgtttt 60 taatcactcc tgtgctactg tactgtttta tattgttttt gatttgtgag ttctctagtg 120 taatttctcc tgagccagtt gagttatctg aatatttcac attgtaaggg tttctgatgg 180 tactacctac a 191 <210> 1216 <211> 191 <212> DNA <213> Artificial Sequence <400> 1216 tgaccaaacg ggtaagaagt tcacttggaa ctttgagcat atccaatcaa acaacggaat 60 taatccagtt acaaaaaacc catttaccta caatgcacct gtagcaaaca aagcttccgt 120 tgttaaatca tctagatggc tactcaagta taaagactca gtagccacaa gggaggtagt 180 ggataaggta a 191 <210> 1217 <211> 191 <212> DNA <213> Artificial Sequence <400> 1217 ggctcgtcca tgggttcaaa ccgttcatgt ttcgtattaa cgtttctcat actttgtacc 60 accattgaca gtcgtaagct cagtaattga cttactttgt gcctccatga tggcgactaa 120 gtatttgagc tctacactat aacgcacatt taacatcaat gaaattgcca aaataacacc 180 tagaataatt g 191 <210> 1218 <211> 190 <212> DNA <213> Artificial Sequence <400> 1218 ttgattgtcc tgcatttact gtgattgttt ttcctgttgc tgtccatgat gtgtctaata 60 cgattgaggc gtcatatcta cgccatacaa acgaagtaaa attatcagta atgtcatcct 120 tgcctttgac aactttagct gatatactga ttgtaccctc accatttaca aaaaactgtt 180 tagacggtgt 190 <210> 1219 <211> 190 <212> DNA <213> Artificial Sequence <400> 1219 atgagaaagt acgcgctgag ggaatgcgtt tacaggagca agaaatagaa aagaaagtga 60 ctatacgcgt ggatggggac caggatgaag ttgaggatga gtttgttatt gttaagattg 120 ctaaaaatga tttaggtaac cttgatgttg cgtatgagct agtataacaa cgttttacac 180 ataaatggta 190 <210> 1220 <211> 190 <212> DNA <213> Artificial Sequence <400> 1220 gacggtcaac tatatgtttt gacagatatg cataatatgt attttatttt tgaccatgag 60 gactatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 120 gtacacaaag ccaaaatgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 180 cgcgtaaacg 190 <210> 1221 <211> 190 <212> DNA <213> Artificial Sequence <400> 1221 actatgacag tcacaactga ggttgacaac caaggttata ccgctcagtt tgagattcac 60 tagtgcccaa tgtgcggtgg taagctgatt ggaggaggtt tttgacgttt acttacaacc 120 tgaggaggta ttttaatgtt taaggttgaa catgttagat taacagaata taatgacgcc 180 tatatgagtg 190 <210> 1222 <211> 190 <212> DNA <213> Artificial Sequence <400> 1222 cgtcctctaa acgtgcgtca atacgctcca tggttaattg cattttgata aagttgtcct 60 cagtcattgg cattcgttcc cgctcctaac tttgattgta tgctagtcta tttatcattt 120 tactcatgta gtcaacttgg ttctgtaacg tgtctactgc gttatcttga gtgctatatc 180 cgtttagttc 190 <210> 1223 <211> 190 <212> DNA <213> Artificial Sequence <400> 1223 accttttgtg ttaaatgcgc ggttagatgg gagttctgtg tacatttttc caaacaatgg 60 tgagcctatg attttggtca ttagaataga ctttccattt cctccgttgc gtgtaccgcg 120 tgagacacca atttgagcat gaacagcctc aggtttgttc tcatagacgc atgaccctat 180 gaactcacat 190 <210> 1224 <211> 190 <212> DNA <213> Artificial Sequence <400> 1224 attagtaagg tatttataca cacccgctgt acctacagac gtatctaggc tcccgctctc 60 aaacgcctca gtaacacgtg acgtaagagc gctagtagct ttcttaatca ttccacgggc 120 aacgtctcga ggatatttta tgagacctga ggtgtctact acgctagaga atactttttc 180 aactaatttg 190 <210> 1225 <211> 190 <212> DNA <213> Artificial Sequence <400> 1225 agtgatgtta tgggatacac taacacacct acagccacgc gagtaggtag aacggttcaa 60 atcgcaggtg cgtttaaacc cataaaccaa cttagcgcag gtcaatatgt cattaaccaa 120 cctctaccag tttgggctag accattgaat aacgtaacac tcattcatca aggttctgga 180 atgaacaggc 190 <210> 1226 <211> 190 <212> DNA <213> Artificial Sequence <400> 1226 attagtaagg tatttataca cacccgctgt acctacagac gtatctaggc tcccgctctc 60 aatcgcctca gtaacacgtg acgtaagagc gctagtagct ttcttaatca ttccacgggc 120 aacgtctaga ggatatttta tgagacctga ggtgtctact acgctagaga atactttttc 180 aactaatttg 190 <210> 1227 <211> 190 <212> DNA <213> Artificial Sequence <400> 1227 tagcatatca tctaaaacct caatctcatt catttgtaac tcaccttttt caaccttttc 60 caatttactg tagtatgcta aaatctcgcg cattgttcgt acagttactt tctccgctgt 120 aaatgtttgt tttttacctt ttacttttag ttctaattta atcattataa ttcctcctaa 180 tatgttatgt 190 <210> 1228 <211> 190 <212> DNA <213> Artificial Sequence <400> 1228 gactatagaa tattcaaacg ggaacatgcg agtgttgttt aacgactcat caactaacag 60 aatagtctat tatagcaatg acttattaac caactacttg ccagcaggag ttaaatattc 120 cgtcacatta gacgcattca gcaacaataa tgggttaatt agggtaggta attttgacgc 180 tctcagtaca 190 <210> 1229 <211> 190 <212> DNA <213> Artificial Sequence <400> 1229 cgtttacgcg cgcgttagag ccatccattg ggaaaatttt caaacgcacg tacattttgg 60 ctgtgtgtac aattcccgtt tcctttacag cctccttttc tttcagttca aattttgact 120 caatatattc ctcatggtca aaaataaaat acatattatg catatctgtc aaaacatata 180 gttgaccgtc 190 <210> 1230 <211> 190 <212> DNA <213> Artificial Sequence <400> 1230 caatttgagc atgaacagcc tcaggtttgt tctcatagac gcatgaccct atgaactcac 60 atcatgcttt ttcacttagt gggtcagtaa agaagttgac cgcttgccat agtctatttt 120 tctcaatctc tggtagcgtc acaggtgtct cttttacatg aatgggtaaa atggtgtctt 180 gcgttctata 190 <210> 1231 <211> 190 <212> DNA <213> Artificial Sequence <400> 1231 tggaaaaggt tgaaaaaggt gagttacaaa tgaatgagat tgaggtttta gatgatatgc 60 tatacttagt tctctccatt ttctcaaaca caaaacttac ttatgatatg ttagtggata 120 acgtagcctt tgaggactta ttaccattag tacagggagt ctttgaacaa gtcaacgggg 180 gtacagtttc 190 <210> 1232 <211> 190 <212> DNA <213> Artificial Sequence <400> 1232 atttgaaccg ttctacctac tcgcgtggct gtaggtgtgt tagtgtatcc cataacatca 60 ctctatcttt gccaacctga cgcagggtcc aacatggttg tttcaacttt aattaaatca 120 tgaatttcca gctttgagtt acctaatgaa acgcgcgaat ctgttagacg caaacctgta 180 ctactatact 190 <210> 1233 <211> 190 <212> DNA <213> Artificial Sequence <400> 1233 atgcgtaagc tgtgtgtaaa aatggatttt gaccatcctg tacgtttgca atactcaatg 60 gctttgactc taatgccatg ttttttacct cctctaataa tctacagaac aataatatgt 120 atatacaatt gattgtcctg catttactgt gattgttttt cctgttgctg tccatgatgt 180 gtctaatacg 190 <210> 1234 <211> 190 <212> DNA <213> Artificial Sequence <400> 1234 gttacgtgat tctagctctt tgatgtcgtc ctctagtttg ttaacatggt caattgactg 60 cgaaagacgt ttgtctaggt ccgcgatttg ttgacgggca ccagacagct cttttttaat 120 ctctctcccg tcctctaaac gtgcgtcaat acgctccatg gttaattgca ttttgataaa 180 gttgtcctca 190 <210> 1235 <211> 189 <212> DNA <213> Artificial Sequence <400> 1235 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tagtgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt catggctata 120 tagactcttc tgttagttga tgagtcgtta aacaacactc gcatgttccc gtttgaatat 180 tctatagtc 189 <210> 1236 <211> 190 <212> DNA <213> Artificial Sequence <400> 1236 ttaaaggagg aataaagatg ttaggttgtg attattgtaa atttgaacca atgagggaga 60 cactattttc ctcagattac ttatggagtg ggaggactga catgactgag gtgtttataa 120 acgggaacac tatgacagtc acaactgagg ttgacaacca aggttatacc gctcagtttg 180 agattcacta 190 <210> 1237 <211> 190 <212> DNA <213> Artificial Sequence <400> 1237 gacggtcaac tatatgtttt gacagatatg cataatatgt attttatttt tgaccatgag 60 gactatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 120 gtacacacag ccaaaatgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 180 cgcgtaaacg 190 <210> 1238 <211> 190 <212> DNA <213> Artificial Sequence <400> 1238 attagtaagg tatttataca cacccgctgt acctacagac gtatctaggc tcccgctctc 60 aatcgcctca gtaacacgtg acgtaagagc gctagtagct ttcttaatca ttccacgggc 120 aacgtctcga ggatatttta tgagacctga ggtgtctact acgctagaga atactttttc 180 aactaatttg 190 <210> 1239 <211> 190 <212> DNA <213> Artificial Sequence <400> 1239 tgacggtgta tagaccatga gggtgttagg tatggtttca tgtcctaagt ctttcattaa 60 ggtagtaaaa gagtgtattc cgtttgcttt accttttacg tcacagtcta ctactaataa 120 tttgtttagt tccccacata agaccccttt attcatgttt cttattttac ctaatgtttt 180 gtaactctct 190 <210> 1240 <211> 189 <212> DNA <213> Artificial Sequence <400> 1240 ggtaaaattg cctattaata cattgtttgg tgccacaggt gcagagttta atgggttata 60 tgacccacgt tttcaatttc taacatgtgt gagtgggcaa ttaattatgg ctgacttcta 120 cgagggaatt agggaccatg ttaccatgtt acagagcaac acagactgtc acgcctacat 180 tcctcatga 189 <210> 1241 <211> 189 <212> DNA <213> Artificial Sequence <400> 1241 tcattagttg tagccatgag tatatagttt gctgccataa tttgacgatg tgcgttttta 60 atcactcctg tgctactgta ctgttttata ttgtttttga tttgtgagtt ctctagtgta 120 atttcacctg agccagttga gttatctgaa tatttcacat tgtaagggtt tctgatggta 180 ctacctaca 189 <210> 1242 <211> 189 <212> DNA <213> Artificial Sequence <400> 1242 cttataagga gagtgaacct aatgtccaat agatgggaaa cgcctgagaa ccttgataaa 60 gaggataaag ttctattact tcgtgaacgt aataacctca ttagagaaaa cgaaatgcta 120 agggaaatgt tgttagacgc tcgtttagag gtagacgagt tagcagatga ggttgaccat 180 aaaagtcaa 189 <210> 1243 <211> 189 <212> DNA <213> Artificial Sequence <400> 1243 atcataagta agttttgtgt ttgagaaaat ggagagaact aagtttagca tatcatctaa 60 aacctcaatc tcattcattt gtaactcacc tttttcaacc ttttccattt tactgtagta 120 tgctaaattc tcgcgcattg ttcgtacagt tactttctcc gctgtaaatg tttgtttttt 180 accttttac 189 <210> 1244 <211> 189 <212> DNA <213> Artificial Sequence <400> 1244 ttagggacca tgttaccatg ttacagagca acacagactg tcacgcctac attcctcatg 60 aggaggtggc tgaacgtatt acagacgcgt tcggtgatga catttctgag cgcgtaggta 120 ttgtattgga caaagatgag ttcattgcct tattccagaa agatgtcaac aattatattg 180 gtattgacg 189 <210> 1245 <211> 189 <212> DNA <213> Artificial Sequence <400> 1245 tacacatata agggttcccc agagtttgtt attgaacgta tgcaaacagg agaggttttt 60 cagattatgc tactaagctc tgtgcccgtg aatgtagtaa tacaaccgta ctacattgtt 120 agtgttgtat attaaggagg aaaacaatgg ttaaagttaa tgaactaaaa gtcggagatg 180 ttttaattt 189 <210> 1246 <211> 189 <212> DNA <213> Artificial Sequence <400> 1246 ctgaccagct accacggttg tttgtgatac acctaaccgc ttttgtgcct cagctagtag 60 atacatagcg cgtgagcgtt tggctttgtc tagtggaata accatttcag gtttattacc 120 ctctcccccc atagctaaat gttctcgtgt gatgagtcca ccgttagcat aaccagtacc 180 gcgccatcc 189 <210> 1247 <211> 189 <212> DNA <213> Artificial Sequence <400> 1247 ttaaaaacgc acatcgtcaa attatggcag caaactatat actcatggct acaactaatg 60 acgcaggtaa cacaaactac aatcaattat atctagaccc tgacgcacta aatctacaaa 120 cattcagttc caacccaaac tctggtggca atggctacgg tgcagagtat agtagtacag 180 gtttgcgtc 189 <210> 1248 <211> 189 <212> DNA <213> Artificial Sequence <400> 1248 ttgaaccctt ataatttaga accagaggta tttaaacaac aaattacggc tacacgcatt 60 atggtgaatg aaaagggtaa ggctgaatat gacgcgcgct ttggcggaca ctttgcgggt 120 gctagtaatg atgtatttaa agtacgtgac gcctcagatg gttcgttaag acgtattttg 180 ccaattatt 189 <210> 1249 <211> 189 <212> DNA <213> Artificial Sequence <400> 1249 ggatggcgcg gtactggtta tgctaacggt ggactcatca cacgagaaca tttagctatg 60 gtgggagagg gtaataaacc tgaaatggtt attccactag acaaagccaa acgctcacgc 120 gctatgtctc tactagctga ggcacaaaag cggttaggtg tatcacaaac aaccgtggta 180 gctggtcag 189 <210> 1250 <211> 189 <212> DNA <213> Artificial Sequence <400> 1250 gcacctaaag cgcttgccat aataatgttg aaagcaagtt tttcctcatc tactttttta 60 cagtatttca acttatcaaa atcaaacttt agttcctgta agacgttctc aaacgctttg 120 tgtgtttctt ctttattcat ctgttttcct cctaatgttt taatacattt attagtttat 180 caaaacccc 189 <210> 1251 <211> 189 <212> DNA <213> Artificial Sequence <400> 1251 ggggttttga taaactaata aatgtattaa aacattagga ggaaaacaga tgaataaaga 60 ataaacacac aaagcgtttg agaacgtctt acaggaacta aagtttgatt ttgataagtt 120 gaaatacggt aaaaaagtag atgaggaaaa acttgctttc aacattatta tggcaagcgc 180 tttaggtgc 189 <210> 1252 <211> 189 <212> DNA <213> Artificial Sequence <400> 1252 cttataagga gagtgaacct aatgtccaat agatgggaaa cgcctgagaa ccttgataaa 60 gtggataaag ttctattact tcgtgaacgt aataacctca ttagagaaaa cgaaatgcta 120 agggaaaagt tgttagacgc tcgtttagag gtagacgagt tagcagatga ggttgaccat 180 aaaagtcaa 189 <210> 1253 <211> 189 <212> DNA <213> Artificial Sequence <400> 1253 tacacatata agggttcccc agagtttgtt attgaacgta tgcaaacagg agaggttttt 60 ctgattatgc tactaagctc tgtgcccgtg aatgtagtaa tacaaccgta ctacattgtt 120 agtgttgaat attaaggagg aaaacaatgg ttaaagttaa tgaactaaaa gtcggagatg 180 ttttaattt 189 <210> 1254 <211> 189 <212> DNA <213> Artificial Sequence <400> 1254 atcataagta agttttgtgt ttgagaaaat ggagagaact aagtttagca tatcatctaa 60 atcctcaatc tcattcattt gtaactcacc tttttcaacc ttttccattt tactgtagta 120 tgctaaattc tcgcgcattg ttcgtacagt tactttctcc gctgtaaatg tttgtttttt 180 accttttac 189 <210> 1255 <211> 189 <212> DNA <213> Artificial Sequence <400> 1255 cataattaat tgcacaatca cacctgttag atattgataa cgtgggtcat ataacccatt 60 aaagtctgct cctgtggctc catacaatgt tttaataggc tattttaccc catttactta 120 cacatacttt ggtaacgtta cttcgttcat tgtaatctat gtttcatctg tatatttagc 180 ctctagacg 189 <210> 1256 <211> 189 <212> DNA <213> Artificial Sequence <400> 1256 tacacatata agggttcccc agagtttgtt attgaacgta tgcaaacagg agaggttttt 60 ctgattatgc tactaagctc tgtgcccgtg aatgtagtaa tacaaccgta ctacattgtt 120 agtgttgtat attaaggagg aaaacaatgg ttaaagttaa tgaactaaaa gtcggagatg 180 ttttaattt 189 <210> 1257 <211> 189 <212> DNA <213> Artificial Sequence <400> 1257 ttgaacatta agcccgcctt tgtgtctgta gctactacgt caaaacggat ggcacccgct 60 aacatttcac cgtagacatt gtggtcttgc caacgtaccg tcatttcagt acgtttgaac 120 aaagtaagag cttgttctaa gtcaccaatg aataatagtt tatcatttgt gtcgttttta 180 aagatagcg 189 <210> 1258 <211> 189 <212> DNA <213> Artificial Sequence <400> 1258 ttgaacatta agcccgcctt tgtgtctgta gctactacgt caaaacggat ggcacccgct 60 accatttcac cgtagacatt gtggtcttgc caacgtaccg tcatttcagt acgtttgaac 120 aaagtaagag cttgttctaa gtcaccaatg aataatagtt tatcatttgt gtcgttttta 180 aagatagcg 189 <210> 1259 <211> 189 <212> DNA <213> Artificial Sequence <400> 1259 ttgaacatta agcccgcctt tgtgtctgta gctactacgt caaaacggat ggcacccgct 60 accatttcac cgtagacatt gtggtcttgc caacgtaccg tcatttcagt acgtttgaac 120 aaagtaatag cttgttctaa gtcaccaatg aataatagtt tatcatttgt gtcgttttta 180 aagatagcg 189 <210> 1260 <211> 189 <212> DNA <213> Artificial Sequence <400> 1260 gcacctaaag cgcttgccat aataatgttg aaagcaagtt tttcctcatc tactttttta 60 cagtatttca acttatcaaa atcaaacttt agttcctgta agacgttctc aaacgctttg 120 tgtgtttatt ctttattcat ctgttttcct cctaatgttt taatacattt attagtttat 180 caaaacccc 189 <210> 1261 <211> 189 <212> DNA <213> Artificial Sequence <400> 1261 ggatggcgcg gtactggtta tgctaacggt ggactcatca cacgagaaca tttagctatg 60 gggggagagg gtaataaacc tgaaatggtt attccactag acaaagccaa acgctcacgc 120 gctatgtctc tactagctga ggcacaaaag cggttaggtg tatcacaaac aaccgtggta 180 gctggtcag 189 <210> 1262 <211> 189 <212> DNA <213> Artificial Sequence <400> 1262 ttgactttta tggtcaacct catctgctaa ctcgtctacc tctaaacgag cgtctaacaa 60 catttccctt agcatttcgt tttctctaat gaggttatta cgttcacgaa gtaatagaac 120 tttatccact ttatcaaggt tctcaggcgt ttcccatcta ttggacatta ggttcactct 180 ccttataag 189 <210> 1263 <211> 188 <212> DNA <213> Artificial Sequence <400> 1263 tatatgtaaa aaacaacggt gataaaccta tttctatttc aaacagaatg ggagtgggta 60 aaacaatata tcccaatgag agtaagtaca ttagctttga accaacttac accatgggtt 120 caacagagat ggggtttaat ttctactctg acgcaacagg ggacttacct gatattacaa 180 tttggcgc 188 <210> 1264 <211> 188 <212> DNA <213> Artificial Sequence <400> 1264 atctgtttgc tagaagaata ccgtccgtga agagtttcaa ttcaacaagg tcaccctcat 60 gacccgtgtg ctcaaatagt ccactattaa aggctaaatc aataacaggt gttttactac 120 gtactagttc ctcacgcatt tccttagcct catcagatag cgtccacaca aactcgtctg 180 cggtaacg 188 <210> 1265 <211> 188 <212> DNA <213> Artificial Sequence <400> 1265 gctagtctat ttatcatttt actcatgtag tcaacttggt tctgtaacgt gtctactgcg 60 ttatcttgag tgctatatcc gtttagttca taaatgaggt cgtccatggc taacgcgttg 120 ccatggacct cctcctctag aactctgtta aacagcatat ttaactcatc atcaaaccca 180 ttaccgtt 188 <210> 1266 <211> 188 <212> DNA <213> Artificial Sequence <400> 1266 gacggacaaa cgcaccaact tgaactaagt attgatggtc acctatggtg ggtatatgat 60 aaccaaattg aggtattaga ctatgaggag gaaaaataat atgacaaaat tagcagaggt 120 attagaagta catgacgcgg agttagacaa tgttttagat gaattgcgtg cccgcattat 180 ggacgagc 188 <210> 1267 <211> 188 <212> DNA <213> Artificial Sequence <400> 1267 tttccctctc aatttgtttc tattactgtt tggatgttct tgtttgttgt gacaagaaaa 60 tcaaatactt tctaaataat tcatatctaa cctatgttcc catccctcag aggttcgtat 120 ctccgtggta tggtgcacca tgtctgcttt ggtagtgata tctttgctca tacatacttc 180 acagaatg 188 <210> 1268 <211> 188 <212> DNA <213> Artificial Sequence <400> 1268 gttgttggtg acgtttggga ctacgcaact aacccaagca aattagttga aaaagtattc 60 tctagcgtag tagacacctc aggtctcata aaatatcctc tagacgttgc ccgtggaatg 120 attaagacag ctactagcgc tcttacgtca cgtgttactg aggcgtttga gagcgggagc 180 ctagatac 188 <210> 1269 <211> 188 <212> DNA <213> Artificial Sequence <400> 1269 ttttaaattg ctctaacata attatccccc ttagaataaa tcttgacccg catatacgca 60 agagatgttt atccatgcgc ctgacggaat cgcactatct actgtagtac catacctact 120 tactagactt gcaccatcct tgcgcacttc tagtagtagc ctgttcattc cagaaccttg 180 atgaatga 188 <210> 1270 <211> 188 <212> DNA <213> Artificial Sequence <400> 1270 gggggtattt tttagagcgt ctaaaatatt tctaaggtaa ttatacccag aacacttaga 60 acgtatctca gagcctctca gagcgtttta gagcatgttt gtttttgagc gtaaaaaaga 120 gagggttctt tccctctcaa tttgtttcta ttactgtttg gatgttcttg tttgttgtga 180 caagaaaa 188 <210> 1271 <211> 188 <212> DNA <213> Artificial Sequence <400> 1271 gctagtctat ttatcatttt actcatgtag tcaacttggt tctgtaacgt gtctactgcg 60 gtatcttgag tgctatatcc gtttagttca taaatgaggt cgtccatggc taacgcgttg 120 ccatggaact cctcctctag aactctgtta aacagcatat ttaactcatc atcaaaccca 180 ttaccgtt 188 <210> 1272 <211> 188 <212> DNA <213> Artificial Sequence <400> 1272 ttttaaattg ctctaacata attatccccc ttagaataaa tcttgacccg catatacgca 60 cgagatgttt atccatgcgc ctgacggaat cgcactatct actgtagtac catacctact 120 tactagaatt gcaccatcct tgcgcacttc tagtagtagc ctgttcattc cagaaccttg 180 atgaatga 188 <210> 1273 <211> 188 <212> DNA <213> Artificial Sequence <400> 1273 tatatgtaaa aaacaacggt gataaaccta tttctatttc aaacagaatg ggagtgggta 60 caacaatata tcccaatgag agtaagtaca ttagctttga accaacttac accatgggtt 120 caacagatat ggggtttaat ttctactctg acgcaacagg ggacttacct gatattacaa 180 tttggcgc 188 <210> 1274 <211> 188 <212> DNA <213> Artificial Sequence <400> 1274 gttgttggtg acgtttggga ctacgcaact aacccaagca aattagttga aaaagtattc 60 actagcgtag tagacacctc aggtctcata aaatatcctc tagacgttgc ccgtggaatg 120 attaagaaag ctactagcgc tcttacgtca cgtgttactg aggcgtttga gagcgggagc 180 ctagatac 188 <210> 1275 <211> 188 <212> DNA <213> Artificial Sequence <400> 1275 gctcgtccat aatgcgggca cgcaattcat ctaaaacatt gtctaactcc gcgtcatgta 60 attctaatac ctctgctaat tttgtcatat tatttttcct cctcatagtc taatacctca 120 atttggtgat catataccca ccataggtga ccatcaatac ttagttcaag ttggtgcgtt 180 tgtccgtc 188 <210> 1276 <211> 188 <212> DNA <213> Artificial Sequence <400> 1276 tcattcatca aggttctgga atgaacaggc tactactaga agtgcgcaag gatggtgcaa 60 gtctagtaag taggtatggt actacagtag atagtgcgat tccgtcaggc gcatggataa 120 acatctcgtg cgtatatgcg ggtcaagatt tattctaagg gggataatta tgttagagca 180 atttaaaa 188 <210> 1277 <211> 188 <212> DNA <213> Artificial Sequence <400> 1277 gctcgtccat aatgcgggca cgcaattcat ctaaaacatt gtctaactcc gcgtcatgta 60 cttctaatac ctctgctaat tttgtcatat tatttttcct cctcatagtc taatacctca 120 atttggtgat catataccca ccataggtga ccatcaatac ttagttcaag ttggtgcgtt 180 tgtccgtc 188 <210> 1278 <211> 188 <212> DNA <213> Artificial Sequence <400> 1278 cgttaccgca gacgagtttg tgtggacgct atctgatgag gctaaggaaa tgcgtgagga 60 cctagtacgt agtaaaacac ctgttattga tttagccttt aatagtggac tatttgagca 120 cacgggtcat gagggtgacc ttgttgaatt gaaactcttc acggacggta ttcttctagc 180 aaacagat 188 <210> 1279 <211> 188 <212> DNA <213> Artificial Sequence <400> 1279 gctagtctat ttatcatttt actcatgtag tcaacttggt tctgtaacgt gtctactgcg 60 gtatcttgag tgctatatcc gtttagttca taaatgaggt cgtccatggc taacgcgttg 120 ccatggacct cctcctctag aactctgtta aacagcatat ttaactcatc atcaaaccca 180 ttaccgtt 188 <210> 1280 <211> 188 <212> DNA <213> Artificial Sequence <400> 1280 gttgttggtg acgtttggga ctacgcaact aacccaagca aattagttga aaaagtattc 60 actagcgtag tagacacctc aggtctcata aaatatcctc tagacgttgc ccgtggaatg 120 attaagacag ctactagcgc tcttacgtca cgtgttactg aggcgtttga gagcgggagc 180 ctagatac 188 <210> 1281 <211> 188 <212> DNA <213> Artificial Sequence <400> 1281 tatatgtaaa aaacaacggt gataaaccta tttctatttc aaacagaatg ggagtgggta 60 caacaatata tcccaatgag agtaagtaca ttagctttga accaacttac accatgggtt 120 caacagagat ggggtttaat ttctactctg acgcaacagg ggacttacct gatattacaa 180 tttggcgc 188 <210> 1282 <211> 187 <212> DNA <213> Artificial Sequence <400> 1282 gtaggtttta tggtattagg tggcgcttgt ttggctacaa gttttaagct atcaaaggaa 60 ttagagcagg ttgataacat caacgataaa ggagagagtc actaatggga atttttatca 120 gaaacaatcc acacgaagag cgggcaaatc tataccccgt agcaccatca ccaatggttg 180 tggactt 187 <210> 1283 <211> 187 <212> DNA <213> Artificial Sequence <400> 1283 tactagcacc cgcaaagtgt ccgccaaagc gcgcgtcata ttcagcctta cccttttcag 60 tcaccttaat gcgtgtagcc gtaatttgtt gtttaaatac ctctggttct aaattataag 120 ggttcaattc atcaatgaaa atcaactgtt tgtcaactag taacgcacta ttaaactcac 180 cttttgt 187 <210> 1284 <211> 187 <212> DNA <213> Artificial Sequence <400> 1284 ggtggtggta ttgttcagaa agaggctaac gatagaacac cctatagaca atattccaac 60 caggggtatt gtgaaatttc ttcccgtcct gacggtcagt gtgattggga ggatatgtta 120 aattgggttt tggcgtttat tgagacaaac aatttagacg tacaaggtat ttgttatgac 180 cctgcac 187 <210> 1285 <211> 187 <212> DNA <213> Artificial Sequence <400> 1285 cctctaatgc tttagcacgt tccgcgtcca cagatttatc tttattttct tctggttcaa 60 cctcgtctgc ctcatcatcc ttaggttgtt catccttagg ttgctcgtca gggttaacct 120 cgtctgtgtg ttcgtcttgt gcctcacgaa tttccttgat taatttatcc gcctcatcta 180 atttacc 187 <210> 1286 <211> 187 <212> DNA <213> Artificial Sequence <400> 1286 tactagcacc cgcaaagtgt ccgccaaagc gcgcgtcata ttcagcctta cccttttcat 60 tcaccttaat gcgtgtagcc gtaatttgtt gtttaaatac ctctggttct aaattataag 120 ggttcaagtc atcaatgaaa atcaactgtt tgtcaactag taacgcacta ttaaactcac 180 cttttgt 187 <210> 1287 <211> 187 <212> DNA <213> Artificial Sequence <400> 1287 ttggaaatgg tatagtattg aggggggttg tttagacctg ttacaaatga gtcatcccca 60 ttaatatagg ttacttcttc tgtttcaagt tctccgtcct cattttcaac tggatcaagt 120 ttaccggttt ttactttgaa taagttaaca gctttatcac ccgttttcac agcaaacaca 180 cggttta 187 <210> 1288 <211> 187 <212> DNA <213> Artificial Sequence <400> 1288 taaaccgtgt gtttgctgtg aaaacgggtg ataaagctgt taacttattc aaagtaaaat 60 ccggtaaact tgaaccagtt gaaaatgagg acggagaact tgaaacagaa gaagtaacct 120 atattaaagg tgatgactca tatgtaacag gtctaaacaa cccccctcaa tactatacca 180 tttccaa 187 <210> 1289 <211> 187 <212> DNA <213> Artificial Sequence <400> 1289 gaatgagctg acgtatacca tcaatcgttc tacatggtat agggtctctg tgtttctctg 60 tctcaattaa tactttctct gtaggtgtca attcgttttc aggtagttcg tacaagactg 120 ccccaattgg taaaggtgtc gtctcgttgt ttactaactc atatgttttc aaactaattc 180 ctcctct 187 <210> 1290 <211> 187 <212> DNA <213> Artificial Sequence <400> 1290 ttgaacaaag taatagcttg ttctaagtca ccaatgaata atagtttatc atttgtgtcg 60 tttttaaaga tagcgtcagg aagtacaatt acctctttac caaacaatgt attaccactt 120 gccattgcta cgtttggttg aataatgtat cgtccgtctg cgtctttcaa cgtatccaat 180 tgagcaa 187 <210> 1291 <211> 187 <212> DNA <213> Artificial Sequence <400> 1291 acaacgtaca caccgtactc ttttacaacg tcttctggtg tcatttcaat taccccactg 60 tctcaacgtg acaaatctca atttctgagt agtctaaatg ttcttcatat tcaaggtacg 120 gtaacccatt attaatagct tgttcaatag tatatgcgtc aacgtgaata ctacagcaat 180 agtgctc 187 <210> 1292 <211> 187 <212> DNA <213> Artificial Sequence <400> 1292 gtgcagggtc ataacaaata ccttgtacgt ctaaattgtt tgtctcaata aacgccaaat 60 cccaatttaa catatcctcc caatcacact gaccgtcagg acgggaagaa atttcacaat 120 acccctgttt ggaatattgt ctatagggtg ttctatcgtt agcctctttc tgaacaatac 180 caccacc 187 <210> 1293 <211> 187 <212> DNA <213> Artificial Sequence <400> 1293 aatgggatga ggtacaagtt acctttgaac gatttagaga gggctatgag gctcctacgt 60 ggcttacgtt tgatatgttc aaaaccatgc acccacattt agccaatgtg aatgtaactc 120 agtcaaatat aaatgagtcc cttacctcat tctttgaacg atttgacagt gactacaggc 180 aactcaa 187 <210> 1294 <211> 187 <212> DNA <213> Artificial Sequence <400> 1294 tgcggttata ccctcaaatt tatacgttga aggtgtgtca ccttgtttta ttgtttgcca 60 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgcgtc 120 tattgtgtcg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 180 atagact 187 <210> 1295 <211> 187 <212> DNA <213> Artificial Sequence <400> 1295 gctcctgtaa acgcattccc tcagcgcgta ctttctcata ttgctgtact gcctccatta 60 ggtctaaacc gttgtttgca tatacagcta gaatagaggt tcgttggttg cgtatagggt 120 accacgcatt gagttgcctg tagtcactgt caaatcgttc aaagaatgag gtaagggact 180 catttat 187 <210> 1296 <211> 187 <212> DNA <213> Artificial Sequence <400> 1296 actcttcatc cttatcctga actactccaa ctattacagt atcacattca tggaatgtct 60 tagcatgttc taaagcttct tcatagcttg gaaaaacatg gtctaatata tcaataatgt 120 ctcctcccac aacgtacaca ccgtactctt tttcaacgtt ttctggtgtc atttcattta 180 ccccact 187 <210> 1297 <211> 187 <212> DNA <213> Artificial Sequence <400> 1297 aatttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaag 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctattatag caatgactta ttaaccaact acttgccagc aggagttaaa 180 tattccg 187 <210> 1298 <211> 187 <212> DNA <213> Artificial Sequence <400> 1298 cggaatattt aactcctgct ggcaagtagt tggttaataa gtcattgcta taatagactc 60 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 120 tcgcaccctt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 180 ctaaatt 187 <210> 1299 <211> 187 <212> DNA <213> Artificial Sequence <400> 1299 gaatgagctg acgtatacca tcaatcgttc tacatggtat agggtctctg tgattctctt 60 tctcaattaa tactttctcg gtaggtgtca attcgttttc aggtagttcg tccaagactg 120 ccccaatggg taaaggtgtc gtctcgttgt ttactaactc atatgttttc aaactaattc 180 ctcctct 187 <210> 1300 <211> 187 <212> DNA <213> Artificial Sequence <400> 1300 gtgcagggtc ataacaaata ccttgtacgt ctaaattgtt tgtctcaata aacgccaaat 60 cccaatttaa catatcctcc caatcacact gaccgtcagg acgggaagaa atttcacaat 120 acccctggtt ggaatattgt ctatagggtg ttctatcgtt agcctctttc tgaacaatac 180 caccacc 187 <210> 1301 <211> 187 <212> DNA <213> Artificial Sequence <400> 1301 aagtccacaa ccattggtga tggtgctacg gggtatagat ttgcccgctc ttcgtgtgga 60 ttgtttctga taaaaattcc cattagtgac tctctccttt atcgttgatg ttatcaacct 120 gctctaagtc ctttgatagc ttaaaacttg tagccaaaca agcgccacct aataccataa 180 aacctac 187 <210> 1302 <211> 187 <212> DNA <213> Artificial Sequence <400> 1302 ttggaaatgg tatagtattg aggggggttg tttagacctg ttacatatga gtcatcacca 60 ttaatatagg ttacttcttc tgtttcaagt tctccgtcct cattttcaac tggttcaagt 120 ttaccggatt ttactttgaa taagttaaca gctttatcac ccgttttcac agcaaacaca 180 cggttta 187 <210> 1303 <211> 187 <212> DNA <213> Artificial Sequence <400> 1303 tactagcacc cgcaaagtgt ccgccaaagc gcgcgtcata ttcagcctta cccttttcag 60 tcaccttaat gcgtgtagcc gtaatttgtt gtttaaatac ctctggttct aaattataag 120 ggttcaagtc atcaatgaaa atcaactgtt tgtcaactag taacgcacta ttaaactcac 180 cttttgt 187 <210> 1304 <211> 187 <212> DNA <213> Artificial Sequence <400> 1304 agaggaggaa ttagtttgaa aacatatgag ttagtaaaca acgagacgac acctttaccc 60 attggggcag tcttgtacga actacctgaa aacgaattga cacctacaga gaaagtatta 120 attgagacag agaaacacag agaccctata ccatgtagaa cgattgatgg tatacgtcag 180 ctcattc 187 <210> 1305 <211> 186 <212> DNA <213> Artificial Sequence <400> 1305 gtggtaaaat gagtgataat tatgtagact ttagtgacat ctacaaagcg cttggtgaac 60 taggtaaaga cttagaccgt gaggcaaata aaataatgaa cgacatagcg cctgaggttg 120 ctgaggactt tagcaaacgc gtaccatact ggtctaacag taaagcaaaa atgagcggta 180 agcgtg 186 <210> 1306 <211> 186 <212> DNA <213> Artificial Sequence <400> 1306 aaaacaaaat gagtaaagta tttgaggata attttactaa acccctacca gtggggacga 60 aggtgcgctt gattaaacct gaaccaactg aattttttat gaatgagggt tacgagcgtg 120 acagggacta cgttggagag gtgttcagag tagctcatag cgctgaagaa attgacggac 180 aaacgc 186 <210> 1307 <211> 186 <212> DNA <213> Artificial Sequence <400> 1307 ttaagtgtcc agagcgtttg tttgattatg caaaaaccta tatgaaagag tatcataatg 60 tagagttgca ttatgatact aagtcagaag atatttttgt tataagaaat gatatgttcc 120 tatgggacta atgtctaata aggaggaaaa ataaatgatt actgtaacga ttaataaatg 180 gcgaaa 186 <210> 1308 <211> 186 <212> DNA <213> Artificial Sequence <400> 1308 ttaaacccat aaaccaactt agcgcaggtc aatatgtcat taaccaacct ctaccagttt 60 gggctagacc attgaataac gtaacactca gtcatcaagg ttctggaatg aacaggctac 120 tactagaagt gcgcaaggat ggtgcaattc tagtaagtag gtatggtact acagtagata 180 gtgcga 186 <210> 1309 <211> 186 <212> DNA <213> Artificial Sequence <400> 1309 taaataccat ttacgcgcct tgtctaggtc attgacaatt tcccaacgtt taccactaca 60 caaatcttta gcacaaatga caaaatcttg ctcaaatacc tcaatatcat aaattactaa 120 atattgtttc ccgcttggtt tattgggacg cggtggaact tcatcaacct tgcctgcaat 180 ttcagg 186 <210> 1310 <211> 186 <212> DNA <213> Artificial Sequence <400> 1310 gagccattat atattgagat aggtctatca cctttagaca attcctctac taatctatta 60 cacgtttctt tatattgata gccaataaca acgcgttctc ctttagtttc ttctagtatg 120 tcttttatac ggtctgtctt gctgttttta gctactttac ttacatatgg tataaaacca 180 ttagac 186 <210> 1311 <211> 186 <212> DNA <213> Artificial Sequence <400> 1311 gtaccaccta atgctcgtat tgctgtagtt aactcataaa tgttacctgt agttacgatt 60 gaatctacgt cacgcccaac acgtagagta atatctttct cgtcccccat atcctctaca 120 atgttcagtg ttttactttt taactgcatg ttttcaaact caaagtcaat ggtaaactta 180 gcgcct 186 <210> 1312 <211> 186 <212> DNA <213> Artificial Sequence <400> 1312 attgatgagc actattgctg tagtattcac gttgacgcat atactattga acaagctatt 60 aataaagggt tacagtacct tgaatatgaa gaacatttag actactcaga aattgagatt 120 tgtcacggtg agaaagtggg gtaaatgaaa tgacaccaga aaacgttgaa aaagagtacg 180 gtgtgt 186 <210> 1313 <211> 186 <212> DNA <213> Artificial Sequence <400> 1313 tttgctacag gtgcattgta ggtaaatggg ttttttgtaa ctggtttaat tccgttgtgt 60 gattggatat gctcaaagtt ccaagtgaac ttcttacccg tttggtcacg tgtcattgta 120 cagcggaacc aagatgattt gtacttagtt acgtctgtct tgatagattt tagtaacttg 180 ttaccg 186 <210> 1314 <211> 186 <212> DNA <213> Artificial Sequence <400> 1314 taatgtctaa taaggaggaa aaataaatga ttactgtaac gattaataaa tggcgaaatg 60 caaaagtgac acctgttatt gttacaggta cagtagaacc gcctgtaggt aaggaggagt 120 tactcattgg acgtgaggca ttgcttgact tagaaacaga tagcatttac attgaggcta 180 gtgatt 186 <210> 1315 <211> 186 <212> DNA <213> Artificial Sequence <400> 1315 gtggtaaaat gagtgataat tatgtagact ttagtgacat ctacaaagcg cttggtgacc 60 taggtaaaga cttagaccgt gaggcaaata aaataatgaa cgacatagcg cctgaggttg 120 ctgaggaatt tagcaaacgc gtaccatact ggtctaacag taaagcaaaa atgagcggta 180 agcgtg 186 <210> 1316 <211> 186 <212> DNA <213> Artificial Sequence <400> 1316 ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat aatagactct 60 tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat attctatagt 120 cgcaccagtt cctgtccaac cattaatagt ggggtctttc gagaaatcat aattcaatac 180 taaatt 186 <210> 1317 <211> 186 <212> DNA <213> Artificial Sequence <400> 1317 attgtgtata aagtcaagtc accatcaatg gttaagaaac tacgcacaca tagagtatat 60 gaaacagact caggtgacat aattgaatta gataacccta gcaagctgtt taacgcactt 120 agggttgagt ctaatggttt tataccatat gtaagtaaag tagctaaaaa cagcaagaca 180 gaccgt 186 <210> 1318 <211> 186 <212> DNA <213> Artificial Sequence <400> 1318 cctctatcat ctgacttaat aacagcctgt gacaactgaa acgcgtcttt accttgtaaa 60 taaccacgga gcacattatt atcataacta gcagagttat aaccagtaaa tagactgtca 120 cgtacttata aataccattt acgcgccttg tctaggtcat tgacaatttc ccaacgttta 180 ccacta 186 <210> 1319 <211> 186 <212> DNA <213> Artificial Sequence <400> 1319 gagtctgctg agttacttgt cttcagtgct ttagtaactg tgactaatgt tattgatact 60 gtattaattg acggtgactc acctactgaa ttagcactat acgcgcttaa cgtagtacag 120 caaaatgatg ataacgagga cttattaaat gaagttgaga atataattga taaactagag 180 gaggaa 186 <210> 1320 <211> 186 <212> DNA <213> Artificial Sequence <400> 1320 ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat aatagactat 60 tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat attctatagt 120 cgcaccagtt cctgtccaac cattaatagt ggggtctttc gagaaatcat aattcaatac 180 taaatt 186 <210> 1321 <211> 186 <212> DNA <213> Artificial Sequence <400> 1321 aggcgctaag tttaccattg actttgagtt tgaaaacatg cagttaaaaa gtaaaacaat 60 gaacattgta gaggatatgg gggacgagaa agatattact ctacgtgttg ggcgtgacgt 120 agattcactc gtaactacag gtaacattta tgagttaact acagcaatac gagcattagg 180 tggtac 186 <210> 1322 <211> 186 <212> DNA <213> Artificial Sequence <400> 1322 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatcg 60 tcgcaccatt tccagtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aagctg 186 <210> 1323 <211> 186 <212> DNA <213> Artificial Sequence <400> 1323 atccttatcc tgaactactc caactattac cgtatcacat tcatggaatg tcttagcatg 60 ttctaaagct tcttcatagc ttggaaaatc atggtctcat atatcaataa tgtctccgcc 120 aacaacggac acaccgtact ctttttgaac gttttctggt gtcatttcat ttaccccact 180 ttctca 186 <210> 1324 <211> 186 <212> DNA <213> Artificial Sequence <400> 1324 gagtagtgat ggaaaagaga ggttcacact ccaataccca aatgataatt tagtattgta 60 ttatgatttc tcgaaagacc ccactattaa tggttggaca ggaaatggtg cgactataga 120 atattcaaac gggaacatgc gagtgttgtt taacgactca tcaactaaca gaagagtcta 180 ttatag 186 <210> 1325 <211> 186 <212> DNA <213> Artificial Sequence <400> 1325 gtaccaccta atgctcgtat tgctgtagtt aactcataaa tgttacctgt agttacgagt 60 gaatctacgt cacgcccaac acgtagagta atatctttct cgtcccccat atcctctaca 120 atgttcagtg ttttactttt taactgcatg ttttcaaact caaagtcaat ggtaaactta 180 gcgcct 186 <210> 1326 <211> 186 <212> DNA <213> Artificial Sequence <400> 1326 gtggtaaaat gagtgataat tatgtagact ttagtgacat ctacaaagcg cttggtgacc 60 taggtaaaga cttagaccgt gaggcaaata aaataatgaa cgacatagcg cctgaggttg 120 ctgaggactt tagcaaacgc gtaccatact ggtctaacag taaagcaaaa atgagcggta 180 agcgtg 186 <210> 1327 <211> 186 <212> DNA <213> Artificial Sequence <400> 1327 gagtagtgat ggaaaagaga ggttcacact ccaataccca aatgataatt tagtattgta 60 ttatgatttc tcgaaagacc ccactattaa tggttggaca ggaaatggtg cgactataga 120 atattcacac gggaacatgc gagtgttgtt taacgactca tcaactaaca gaatagtcta 180 ttatag 186 <210> 1328 <211> 186 <212> DNA <213> Artificial Sequence <400> 1328 tccgcgtcat gtaattctaa tacctctgct aattttgtca tattattttt cctcctcata 60 gtctaatacc tcaatttggt tatcatatac ccaccatagg tgaccatcaa tacttagttc 120 aagttggagc gtttgtccgt caatttcttc agcgctatga gctactctga acacctctcc 180 aacgta 186 <210> 1329 <211> 185 <212> DNA <213> Artificial Sequence <400> 1329 aaagagggtt agatttaaac cagttttcct cgtcatccgc ctcgtcaaaa ctatccagtt 60 cccaccatag agctaagtag tgttcagcct ctacctcacc tgttaatact ttcatagtca 120 ttggatattc ctccatatga tagtgtccgt ttaggttttg tgaggttgta ctaatcatta 180 agtta 185 <210> 1330 <211> 185 <212> DNA <213> Artificial Sequence <400> 1330 aatcatgtaa tgttagttcc attctattca tcctcctcaa ataagtcata tgttttattc 60 tctggtaatt ttggcaattt atacgtgcta atgtgtcccg tgtctatcaa gtgaaaaata 120 gtttctaact cctgtagttc atcctttagt atgagaccta tgacgccttg ttctctcacg 180 cgttg 185 <210> 1331 <211> 185 <212> DNA <213> Artificial Sequence <400> 1331 tccctctgtt tttccatctg tacataaata taattgtggg aaaccccacg cgctccagtc 60 actaaaacca attacacgca caaccgtacc atctttaaag ttacaatcac tatcccacgg 120 tgtcacaatg cactctaaac ccttttttat catagcacca acctcacaac ttctataacg 180 cgttc 185 <210> 1332 <211> 185 <212> DNA <213> Artificial Sequence <400> 1332 ctgtggataa gatgagggta gtattattta aaattgtctg tgcaatataa tcaatatcac 60 caacgacaaa gcgcgaacct ctgttcgtgt actcaatgtc tataggtagg tccaccttat 120 cgcgacacta ggttaatgga taaatgtctt ttacttctgg tgtcatttct gtgtgtattg 180 tagga 185 <210> 1333 <211> 185 <212> DNA <213> Artificial Sequence <400> 1333 aaagagggtt agatttaaac cagttttcct cgtcatccgc ctcgtcaaaa ctatccattt 60 cccaccatag agctaagtag tgttcagcct ctacctcacc tgttaatact ttcatagtca 120 ttggatagtc ctccatatga tagtgtccgt ttaggttttg tgaggttgta ctaatcatta 180 agtta 185 <210> 1334 <211> 185 <212> DNA <213> Artificial Sequence <400> 1334 gaacgcgtta tagaagttgt gaggttggtg ctatgataaa aaagggttta gagtgcagtg 60 tgacaccgtg ggatagtgat tgtaacttta aagatggtac ggttgtgcgt gtaattggtt 120 ttagtgaatg gagcgcgtgg ggtttcccac aattatattt atgtacagat ggaaaaacag 180 aggga 185 <210> 1335 <211> 185 <212> DNA <213> Artificial Sequence <400> 1335 ttgatagttc caaactcaat aaagtgcgcg cgccacgcaa cctcatcatc aaagccactt 60 tctacatatc catctttggc tttgctatag ataacatggt ctctcatatg ctcacccata 120 tatgaaccac gcttaccgct catttttgct ttactgttag accagtatgg tacgcgtttg 180 ctaaa 185 <210> 1336 <211> 185 <212> DNA <213> Artificial Sequence <400> 1336 ttagttgccc ctgcggttat accctcaaat ttatacgttg aaggtgtgtc accatgtatt 60 attgtttgcc atgtactgag agcgacaaaa ttacctaccc taattaaccc attatagatg 120 ctgaatgcgt ctattgtgac ggaatattta actcctgctg gcaagtagtt ggttaataag 180 tcatt 185 <210> 1337 <211> 185 <212> DNA <213> Artificial Sequence <400> 1337 tggctttgat gatgaggttg cgtggcgcgc gcactttatt gagtttggaa ctatcaatca 60 accacctcaa cacgtgatag aaaagtcttt agacgcattg tctaaagatg tacagaaacg 120 tgtagaggat gaatttagga ggcgttatat gtgaaactaa ctacaacact aattgcggat 180 aaact 185 <210> 1338 <211> 185 <212> DNA <213> Artificial Sequence <400> 1338 tgttatttaa ttattatcat caaaatgtac cccaacaagg tgtccccatc aagttacccc 60 ttgcgctgac gtaaaaagta tgctaacata ataaacgaag aacgaaagga gaaaacaggc 120 atgatgagtc ctacaataca cacagaaatg acaccagaag taaaagacat ttatccatta 180 accta 185 <210> 1339 <211> 185 <212> DNA <213> Artificial Sequence <400> 1339 tgtcctcatt ttcctcaagt gctctaatct caatgctacg cgtctccgtt ttcatcatta 60 gtagcctcct tattttgatt gtttgtttct cgtgaaacat taatacgtga gcctgtcatt 120 ctagaaaact gactctcgtc tgtttcagga taaccatagt aggcgcgtac ctcgttaggt 180 ttaag 185 <210> 1340 <211> 185 <212> DNA <213> Artificial Sequence <400> 1340 gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata atagactctt 60 ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata ttctatagtc 120 gcaccatgtc ctgtccaacc attaatagtg gggtctttcg agaaatcata attcaatact 180 aaatt 185 <210> 1341 <211> 185 <212> DNA <213> Artificial Sequence <400> 1341 ataaagaagt tataattgga ggaggttcac catggaacga attatatatt tacctatgat 60 tatgtatata ctagcgtgtg tttttatggc tattggtgcc tttttggtag atataaccgt 120 aggttttttg gtattaggtg gcgcttgttt ggctacaagt tttaagctat caaaggaatt 180 agagc 185 <210> 1342 <211> 185 <212> DNA <213> Artificial Sequence <400> 1342 aagtaccaaa gtccacaacc attggtgatg gtgctacggg gtatagattt gcccgctctt 60 cgtgtggctt gtttctgata aaaattccca ttagtgactc tctcctttat cgttgatgtt 120 atcaaccagc tctaattcct ttgatagctt aaaacttgta gccaaacaag cgccacctaa 180 tacca 185 <210> 1343 <211> 185 <212> DNA <213> Artificial Sequence <400> 1343 ttaaaatctc cctctcttat ttcatatagt gttattatac catttatgtg taaaacggtg 60 ttatactagc tcatacgcaa catcaaggtt acctaaatca tttttagcaa tcttaacaat 120 aacaaactca tcctcaactt catcctgttc cccatccacg cgaatagtca ctttcttttc 180 tattt 185 <210> 1344 <211> 185 <212> DNA <213> Artificial Sequence <400> 1344 gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata atagactatt 60 ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata ttctatagtc 120 gcaccatgtc ctgtccaacc attaatagtg gggtctttcg agaaatcata attcaatact 180 aaatt 185 <210> 1345 <211> 185 <212> DNA <213> Artificial Sequence <400> 1345 tccctctgtt tttccatctg tacataaata taattgtggg aaaccccacg cgctccagtc 60 actaaaacca attacacgca caaccgtacc atctttaaag ttacaatcac tatcccacgg 120 tgtcacactg cactctaaac ccttttttat catagcacca acctcacaac ttctataacg 180 cgttc 185 <210> 1346 <211> 185 <212> DNA <213> Artificial Sequence <400> 1346 taacttaatg attagtacaa cctcacaaaa cctaaacgga cactatcata tggaggacta 60 tccaatgact atgaaagtat taacaggtga ggtagaggct gaacactact tagctctatg 120 gtgggaactg gatagttttg acgaggcgga tgacgaggaa aactggttta aatctaaccc 180 tcttt 185 <210> 1347 <211> 184 <212> DNA <213> Artificial Sequence <400> 1347 tgtgcgataa gttcacgggc ttctagtaat cgtttatcca tgtttcacac tccttagtat 60 gtttcttaaa taattataac acgcgtttat taaccgcggg tgagttagct gtatcacatt 120 aattctaaaa tgtcaagttc taattctaat tttctttttt gttctttaaa cgctttttgt 180 gacc 184 <210> 1348 <211> 184 <212> DNA <213> Artificial Sequence <400> 1348 tgcttgggtt agttgcgtag tcccaaacgt caccaacaac actgctaacc ttatcacacg 60 cacttttagc catgtttttg gcaccgttcc agatgttttt tacgcctcct gtaattttgt 120 caaagaagcc agtacctttt ttgtatgcaa acttaggacg tttatgacct aacacttgtg 180 cagt 184 <210> 1349 <211> 184 <212> DNA <213> Artificial Sequence <400> 1349 tgataaggtt agcagtgttg ttggtgacgt ttgggactac gcaactaacc caagcacatt 60 agttgaaaaa gtattctcta gcgtagtaga cacctcaggt ctcataaaat atcctctaga 120 cgttgcccgt ggaatgatta agaaagctac tagcgctctt acgtcacgtg ttactgaggc 180 gttt 184 <210> 1350 <211> 184 <212> DNA <213> Artificial Sequence <400> 1350 tgttagtttg tcaagtgtat tacctagttc agcggttccg tcaataccta aaccaatctt 60 catatttcct actggttttc cgctttgcac catgtgttaa tcagctcctt ttttctctag 120 cttttcaagt tcctcaggac ttaagaaacg cttaataaag tcagcgccat ccatcacctt 180 ttct 184 <210> 1351 <211> 184 <212> DNA <213> Artificial Sequence <400> 1351 ccagatgtgc ccacgcggtc acgtacttta ttcagagcaa taacgtagcc aacttgtgat 60 ttaaagttat caaaagcata gttacccgct tgacggtatt tacttgaccc gttcatgctt 120 gcaggaactg ctacgtcaat agcgtttctt gaaccgtgac tatatgggtc tcctggtcta 180 tatc 184 <210> 1352 <211> 184 <212> DNA <213> Artificial Sequence <400> 1352 tccatttgtg ccttcttgtc taatctaatc tgtgtattga ctgtactact ccctattttc 60 tcactagtat aaaacactaa cgtatcatct aaatcatata cgtcaatcat atcctcgtta 120 tactcaatat catgtaatgt tagttccatt ctattcatcc tcctcaaata agtcatatgt 180 ttta 184 <210> 1353 <211> 184 <212> DNA <213> Artificial Sequence <400> 1353 ctaaagttgt caaaggcaag gatgacatta ctgataattt tacttcgttt gtatggagta 60 gatatgacgc ctcaaacgta ttagacacat catggacagc aacaggaaat acaatcacag 120 taaatgcagg acaatcaaat gtatatacat agtcttgttc tgtagattat ttgaggaggt 180 aaaa 184 <210> 1354 <211> 184 <212> DNA <213> Artificial Sequence <400> 1354 tgttagtttg tcaagtgtat tacctagttc agcggttccg tcaataccta aaccaaactt 60 catatttcct actggttttc cgctttgcac catgtgttaa tcagctcctt ttttctctag 120 cttttcatgt tcctcaggac ttaagaaacg cttaataaag tcagcgccat ccatcacctt 180 ttct 184 <210> 1355 <211> 184 <212> DNA <213> Artificial Sequence <400> 1355 gatatagacc aggagaccca tatagtcacg gttcaagaaa cgctattgac gtagcatttc 60 ctgcaagcat gaacgggtca agtaaatacc gtcaagcggg taactatgct tttgataact 120 ttaaatccca agttggctac gttattgctc tgaataaagt acgtgaccgc gtgggcacat 180 ctgg 184 <210> 1356 <211> 184 <212> DNA <213> Artificial Sequence <400> 1356 tagtcacagt tactaaagca ctgaagacaa gtaactcagc agactcaata cccgttgtct 60 catttaactc acgcgccttt tcaaccacta aatcacctaa ttttgtagta tctaaattca 120 tgtctatttt cctcccttat ttggttgaaa caaccattta gaaaacatta gtgacaaccc 180 tata 184 <210> 1357 <211> 184 <212> DNA <213> Artificial Sequence <400> 1357 gacttgtaac tagtcttgga acctgcacga atgtgtagga cttccttaga tttcattgtc 60 catgttacct tatccactac ctcccttgtg gctactgagt ctttatactt gagtagccat 120 ctagatgatt taacaacgga agctttgttt gctacaggtg cattgtaggt aaatgggttt 180 tttg 184 <210> 1358 <211> 184 <212> DNA <213> Artificial Sequence <400> 1358 caaaaaaccc atttacctac aatgcacctg tagcaaacaa agcttccgtt gttaaaacat 60 ctagatggct actcaagtat aaagactcag tagccacaag ggaggtagtg gataaggtaa 120 catggaccat gaaatctaag gaagtcctac acattcgtgc aggttccaag actagttaca 180 agtc 184 <210> 1359 <211> 184 <212> DNA <213> Artificial Sequence <400> 1359 agaatattca aacgggaaca tgcgagtgtt gtttaacgac tcatcaacta acagaatagt 60 ctattatagc aatgacttat taaccaacta cttgccagca ggagttaaat attccgtcac 120 aatagactca ttcagcaaca ataatgggtt aattagggta ggtaattttg acgctctcag 180 taca 184 <210> 1360 <211> 184 <212> DNA <213> Artificial Sequence <400> 1360 ccatacaaac gaagtaaaat tatcagtaat gtcatccttg cctctgacaa ctttagatga 60 tatactgatt gtaccctcac catttacaaa aaactgttta gacggtgtaa taattacctc 120 agacggaatt ctgttgtcaa actgttttga aaaatctgac gctatctgta gcaactgagg 180 gtca 184 <210> 1361 <211> 184 <212> DNA <213> Artificial Sequence <400> 1361 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgaatgagtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 ttct 184 <210> 1362 <211> 184 <212> DNA <213> Artificial Sequence <400> 1362 gacttgtaac tagtcttgga acctgcacga atgtgtagga cttccttaga tttcatggtc 60 catgttacct tatccactac ctcccttgtg gctactgagt ctttatactt gagtagccat 120 ctagatgatt taacaacgga agctttgttt gctacaggtg cattgtaggt aaatgggttt 180 tttg 184 <210> 1363 <211> 184 <212> DNA <213> Artificial Sequence <400> 1363 gatatagacc aggagaccca tatagtcacg gttcaagaaa cgctattgac gtagcagttc 60 ctgcaagcat gaacgggtca agtaaatacc gtcaagcggg taactatgct tttgataact 120 ttaaatccca agttggctac gttattgctc tgaataaagt acgtgaccgc gtgggcacat 180 ctgg 184 <210> 1364 <211> 184 <212> DNA <213> Artificial Sequence <400> 1364 tgttagtttg tcaagtgtat tacctagttc agcggttccg tcaataccta aaccaatctt 60 catatttcct actggttttc cgctttgcac catgtgttaa tcagctcctt ttttctctag 120 cttttcatgt tcctcaggac ttaagaaacg cttaataaag tcagcgccat ccatcacctt 180 ttct 184 <210> 1365 <211> 183 <212> DNA <213> Artificial Sequence <400> 1365 gttttccgct ttgcaccatg tgttaatcag ctcctttttt ctctagcttt tcaaggtcct 60 caggacttaa gaaacgctta ataaagtcag cgccatccat caccttttct tgtttagact 120 ctttaccaaa caattgtaat aaaagaaagt agtcagcgtt ctctatctct gagagttgcc 180 agc 183 <210> 1366 <211> 183 <212> DNA <213> Artificial Sequence <400> 1366 tcaataccta tggacacgta ttatctggac atttacagat aatagtaacc aaacacccta 60 ctcagtggcg cgctttggtc aggatggtat tagtgtgact ggtactcaat cagagtatgt 120 acaaacaact agttctgtag aacctacctc aggatggagt acaacacgtc caacacctca 180 aat 183 <210> 1367 <211> 183 <212> DNA <213> Artificial Sequence <400> 1367 gatagatttt agtaacttgt taccgtacca gtattcaaca atcacttcat tgcctgttgc 60 gtcagagtca cggatggcta tagacattaa tatgtcatta gcgtctgtca aaataaccaa 120 ctcataacgt ccgttctttt ctgacgtagt accgaagtct atccgttcct caaatttaaa 180 ggc 183 <210> 1368 <211> 183 <212> DNA <213> Artificial Sequence <400> 1368 tttgtaactg gtttaattcc gttgtttgat tggatatgct caaagttcca agtgaacttc 60 ttacccgttt ggtcacgtgt cattgtacag cggaaccaag atgatttgta cttagttacg 120 tctgtctgga tagattttag taacttgtta ccgtaccagt attcaacaat cacttcattg 180 cct 183 <210> 1369 <211> 183 <212> DNA <213> Artificial Sequence <400> 1369 tcaataccta tggacacgta ttatctggac atttacagat aatagtaacc aaacaaccta 60 ctcagtggcg cgctttggtc aggatggtat tagtgtgact ggtactcaat cagagtatgt 120 acaaacacct agttctgtag aacctacctc aggatggagt acaacacgtc caacacctca 180 aat 183 <210> 1370 <211> 183 <212> DNA <213> Artificial Sequence <400> 1370 gctggcaact ctcagagata gagaacgctg actactttct tttattacaa ttgttgggta 60 aagagtctaa acaagaaaag gtgatggatg gcgctgactt tattaagcgt ttcttaagtc 120 ctgaggaact tgaaaagcta gagaaaaaag gagctgatta acacatggtg caaagcggaa 180 aac 183 <210> 1371 <211> 183 <212> DNA <213> Artificial Sequence <400> 1371 tttattattt tgacgagtta agttcgtcaa ttgtgtcatt gtatgcagta gctagtttat 60 tcatgaggtc accaattttt ccaattattt ggtctggttc attaccccct aaaaggttac 120 ccatatctac cgcatcgcag acgtcaatca tctgtgtaat agcactcttt acaattcctg 180 act 183 <210> 1372 <211> 183 <212> DNA <213> Artificial Sequence <400> 1372 atgggttaat tagggtaggt aattttgacg ctctcagtac atggcaaaca ataaatcaag 60 gtgacacacc ttcaacgtat aaatttgagg gtataaccgc aggggcaact aatgctttta 120 gtatacaggg taattcaaat gctttaatta taactataac aaaaataaaa atcgaactag 180 gaa 183 <210> 1373 <211> 183 <212> DNA <213> Artificial Sequence <400> 1373 atttgaggtg ttggacgtgt tgtactccat cctgaggtag gttctacaga actaggtgtt 60 tgtacatact ctgattgagt accagtcaca ctaataccat cctgaccaaa gcgcgccact 120 gagtagggtg tttggttact attatctgta aatgtccaga taatacgtgt ccataggtat 180 tga 183 <210> 1374 <211> 183 <212> DNA <213> Artificial Sequence <400> 1374 gttttccgct ttgcaccatg tgttaatcag ctcctttttt ctctagcttt tcaaggtcct 60 caggacttaa gaaacgctta ataaagtcag cgccatccat caccttttct tgtttagact 120 ctttacccaa caattgtaat aaaagaaagt agtcagcgtt ctctatctct gagagttgcc 180 agc 183 <210> 1375 <211> 182 <212> DNA <213> Artificial Sequence <400> 1375 atcaccgcac aattgaccaa attggtagat tggtagagat ttcactagtt tcaagtcccg 60 catatgatga tacaactgta gcagtggcac aacggtcaca aaaagcgttt aaagaacaaa 120 aaagaaaatt agaattagaa cttgacattt tagaattaat gtgatacagc taactcaccc 180 gc 182 <210> 1376 <211> 182 <212> DNA <213> Artificial Sequence <400> 1376 tcaaaaccat gcacccacat ttagccaatg tgaatgtaac tcagtcaaaa ataactgagt 60 cccttacctc attctttgaa cgatttgaca gtgactacag gcaactcaaa gcgtggtacc 120 ctatacgcaa ccaacgaacc tctattctag ctgtatatgc aaacaacggt ttagacctaa 180 tg 182 <210> 1377 <211> 182 <212> DNA <213> Artificial Sequence <400> 1377 ggcaagacac tcatggcatt agaatcgttt aaaaaatcag ggctaaagaa actcgtagta 60 gtgtgccttg cgtctaaggt gtctgagtgg gcttctgagg ggtctaaaca aggtttaggt 120 ataattaccc taagtgggtc tccaaagctc agaggagagc ttctagaggc gtcaggaacg 180 ca 182 <210> 1378 <211> 182 <212> DNA <213> Artificial Sequence <400> 1378 agtaggtaac acgcacaatt aattctgttg ttgctagact accagtccac ccctgagaga 60 tgaatacact ccctgataca gtgtacgttg taccgcgcaa agcactgtag ccatttgata 120 ggtatgcagg acgtattgtt gacactgctg ttttagttaa tttagtggct cctgctgttg 180 gt 182 <210> 1379 <211> 182 <212> DNA <213> Artificial Sequence <400> 1379 agtatttgga aacgtgaaaa aggtagatga ttatatgaca cctgttatta atgacagcaa 60 tgagacccgt accattacca tctgcatggt caacggacgc tcttacacat ataagggttc 120 cccagagttt gttattgaac gtatgcaaac aggagaggtt tttcagatta tgctactaag 180 ct 182 <210> 1380 <211> 182 <212> DNA <213> Artificial Sequence <400> 1380 cgttgttagg aatagctcct aatttgaaca ttaagcccgc ctttgtgtct gtagctacta 60 cgtcaaaacg gatggcaccc gctaacattt caccgtagac attgtggtct tgccaacgta 120 ccgtcatgtc agtacgtttg aacaaagtaa tagcttgttc taagtcacca atgaataata 180 gt 182 <210> 1381 <211> 182 <212> DNA <213> Artificial Sequence <400> 1381 atgtgtaaaa cgttgttata ctagctcata cgcaacatca aggttaccta aatcattttt 60 agcaatctta acaataacaa actcatcctc aacttcatcc tgttccccat ccacgcgtat 120 agtcactgtc ttttctattt cttgctcctg taaacgcatt ccctcagcgc gtactttctc 180 at 182 <210> 1382 <211> 182 <212> DNA <213> Artificial Sequence <400> 1382 gggggataat tatgttagag caatttaaaa cggagtatat taacaaggta ttaatcggta 60 atgggtttga tgatgagtta aatatgctgt ttaacagagt tctagaggag gagttccatg 120 gcaacgcgtt agccatggac gacctcattt atgaactaaa cggatatagc actcaagata 180 ac 182 <210> 1383 <211> 182 <212> DNA <213> Artificial Sequence <400> 1383 ttataccctc aaatttatac gttgaaggtg tgtcaccttg ttttattgtt tgccatgtac 60 tgagagcgtc aaaattacct accctaatta acccattatt gttgctgaat gcgtctattg 120 tgacggacta tttaactcct gctggcaagt agttggttaa taagtcattg ctataataga 180 ct 182 <210> 1384 <211> 182 <212> DNA <213> Artificial Sequence <400> 1384 atagggttgt cactaatgtt ttctaaatgg ttgtttcaac caaataaggg aggacaatag 60 acatgaattt agatactaca aaattaggtg atttagtggt tgaaaaggcg cgtgagttaa 120 atgagaaaac gggtattgag tctgctgagt tacttgtctt cagtgcttta gtaactgtga 180 ct 182 <210> 1385 <211> 182 <212> DNA <213> Artificial Sequence <400> 1385 attctttgaa cgatttgaca gtgactacag gcaactcaaa gcgtggtacc ctatacgcaa 60 ccaacgaacc tctattcaag ctgtatatgc aaacaacggt ttagacctac tggaggcagt 120 acagcaagag gcgaaagtac gcgctgaggg aatgcgttta caggagcaag aaatagaaaa 180 ga 182 <210> 1386 <211> 182 <212> DNA <213> Artificial Sequence <400> 1386 tataacaaac agcacttcta tcttattgat tgctttattt tgggtagtta tactagcaga 60 ataccgcacc cagttgtctg tacttgtgtt tgtgattgag acttttccat cttcgcgcgt 120 actatcagag taggtaacac gcacaattaa ttctgttgtt gctagactac cagtccaccc 180 ct 182 <210> 1387 <211> 182 <212> DNA <213> Artificial Sequence <400> 1387 ttaaacaaac actaaattag gggaggaatt taaatgaaca catatacagt ttatgaccgt 60 aacattgatg agcactattg ctgtagtatt cacgttgacg catatactat tgaacaagct 120 attaataaag ggttacagta ccttgaatat gaagaacatt tagactactc agaaattgag 180 at 182 <210> 1388 <211> 182 <212> DNA <213> Artificial Sequence <400> 1388 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattatatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ctccatgcgt 180 aa 182 <210> 1389 <211> 182 <212> DNA <213> Artificial Sequence <400> 1389 tcagtacgtt tgaacaaagt aatagcttgt tctaagtcac caatgaataa tagtgtatca 60 tttgtgtcgt ttttaaagat agcgtcagga agtacaatta cctctttacc aaacaatgtt 120 ttaccacttg ccattgctac gtttggttga ataatgtatc gtccgtctgc gtctttcaac 180 gt 182 <210> 1390 <211> 182 <212> DNA <213> Artificial Sequence <400> 1390 atctcaattt ctgagtagtc taaatgttct tcatattcaa ggtactgtaa ccctgtatta 60 atagcttgtt caatagtata tgcgtcaacg tgaatactac agcaatagtg ctcatcaatg 120 ttacggtaat aaactgtata tgtgttcatt taaattcctc ccctaattta gtgtttgttt 180 aa 182 <210> 1391 <211> 182 <212> DNA <213> Artificial Sequence <400> 1391 gcgggtgagt tagctgtatc acattaattc taaaatgtca agttctaatt ctaagtttct 60 tttttgttct ttaaacgctt tttgtgaccg ttgtgccact gctacagttg tatcatcata 120 tgcgggaatt gaaactagtg aaatctctac caatctacca atttggtcaa ttgtgcggtg 180 at 182 <210> 1392 <211> 182 <212> DNA <213> Artificial Sequence <400> 1392 agcttagtag cataatctga aaaacctctc ctgtttgcat acgttcaata acaatctctg 60 gggaaccctt atatgtgtaa gagcgtccgt tgaccatgca gatggtaatg gtacgggtct 120 cattgctttc attaataaca ggtgtcatat aatcatctac ctttttcacg tttccaaata 180 ct 182 <210> 1393 <211> 182 <212> DNA <213> Artificial Sequence <400> 1393 cgctttggat gttcaaataa aggcgtatag agacgctcag aggtgttcta aatgggatga 60 ggtacaagtt acctttgaac gatttagaga gggctatgag gctcctacgt ggcttacgtt 120 tgatatgatc aaaaccatgc acccacattt agccaatgtg aatgtaactc agtcaaaaat 180 aa 182 <210> 1394 <211> 182 <212> DNA <213> Artificial Sequence <400> 1394 ttttgatgtt ctttctcgta acgtacctga ggagaataag ctcctagtga aagaactctt 60 agataaacgt ctagaggcta aatatacaga tgaaacagag attacaatga tcgaagtaac 120 gttaccactg tatgtgttcg taactggggt aaaattgcct attaatacat tgtttggtgc 180 ca 182 <210> 1395 <211> 182 <212> DNA <213> Artificial Sequence <400> 1395 ttttgatgtt ctttctcgta acgtacctga ggagaataag cacctagtga aagacctctt 60 agataaacgt ctagaggcta aatatacaga tgaaacagag attacaatga acgaagtaac 120 gttaccaatg tatgtgttag taaatggggt aaaattgcct attaatacat tgtttggtgc 180 ca 182 <210> 1396 <211> 182 <212> DNA <213> Artificial Sequence <400> 1396 atctcaattt ctgagtagtc taaatgttct tcatattcaa ggtactgtaa ccctgtatta 60 atagcttgtt caatagtata tgcgtcaacg tgaatactac agcaatagtg ctcatcaatg 120 ttacggtcat aaactgtata tgtgttcatt taaattcctc ccctaattta gtgtttgttt 180 aa 182 <210> 1397 <211> 182 <212> DNA <213> Artificial Sequence <400> 1397 gcgggtgagt tagctgtatc acattaattc taaaatgtca agttctaatt ctaagtttct 60 tttttgttct ttaaacgctt tttgtgaccg ttgtgccact gctacagttg tatcatcata 120 tgcgggactt gaaactagtg aaatctctac caatctacca atttggtcaa ttgtgcggtg 180 at 182 <210> 1398 <211> 182 <212> DNA <213> Artificial Sequence <400> 1398 tagggttgtc actaatgttt tctaaatggt tgtttcaacc aaataaggga ggaacataga 60 catgaattta gatactacaa aattaggtga tttagtggtt gaaaaggcgc gtgagttaaa 120 tgagacaacg ggtattgagt ctgctgagtt acttgtcttc agtgctttag taactgtgac 180 ta 182 <210> 1399 <211> 182 <212> DNA <213> Artificial Sequence <400> 1399 ttttgatgtt ctttctcgta acgtacctga ggagaataag cacctagtga aagacctctt 60 agataaacgt ctagaggcta aatatacaga tgaaacagag attacaatga acgaagtaac 120 gttaccactg tatgtgttag taaatggggt aaaattgcct attaatacat tgtttggtgc 180 ca 182 <210> 1400 <211> 182 <212> DNA <213> Artificial Sequence <400> 1400 atagggttgt aactaatgta ttctaaatgg ttgtttcaac caaataaggg aggaaaatag 60 acatgaattt agatactaca aaattaggtg atttagtggt tgaaaaggcg cgtgagttaa 120 atgagaacac gggtattgag tctgctgagt tacttgtctt cagtgcttta gtaactgtga 180 ct 182 <210> 1401 <211> 182 <212> DNA <213> Artificial Sequence <400> 1401 agtatttgga aacgtgaaaa aggtagatga ttatatgaca cctgttatta atgacagcaa 60 tgagacccgt accattacca tctgcatggt caacggacgc tcttacacat ataagggttc 120 cccagagatt gttattgaac gtatgcaaac aggagaggtt tttcagatta tgctactaag 180 ct 182 <210> 1402 <211> 181 <212> DNA <213> Artificial Sequence <400> 1402 taaaaaacaa acatttacag cggagaaagt aactgtacga acaatgcgcg agattttagc 60 atactacagt aaaatggaaa aggttgaaaa aggtgagtta caaatgaatg agattgagga 120 tttagatgat atgctaaact tagttctctc cattttctca aacacaaaac ttacttatga 180 t 181 <210> 1403 <211> 181 <212> DNA <213> Artificial Sequence <400> 1403 caagtacaga caactgggtg cggtattctg ctagtataac tacccaaaat aaagcaatca 60 ataagataga agtgctgttt gttatagacc cttcgtttgt aggtacgttt tacgtaaaaa 120 actttaatct agaacaaaat gaccatgcta ccccgttcat ccaacacatt acagaacgtg 180 g 181 <210> 1404 <211> 181 <212> DNA <213> Artificial Sequence <400> 1404 catttagcaa ttttgtactt agttgtttta gttgctttac tgattagagt attggtttat 60 atacttatgc gtttgttcta aggagtgata caatgaaata caaacaattt gaggggtttc 120 ctctcaatgc gcgtactaaa attcccgcga taaaagagtg gaaagctcat gagagttaca 180 a 181 <210> 1405 <211> 181 <212> DNA <213> Artificial Sequence <400> 1405 attttgttta ggtcctcgtt aaatcgctct gtaacctcat cttttttagt ccagtctttt 60 gtcttactat tgtagtcctc tttgtacaat gttaatgtgt acagtttaga atagtcctca 120 ggacacacac taatcactaa acttttgtcc tcgtcctcaa ctgctacaac tgttaatttt 180 t 181 <210> 1406 <211> 181 <212> DNA <213> Artificial Sequence <400> 1406 acccattata aacacttcct tttctaatta tattctaata ataccacaga atggagcact 60 tgtaaacaac tttttacatc cctttttata aaataatatg gtataatatg tgtatactta 120 ttatacagtg tttttctccc taaaaagcac tacacgctga ttcctcccaa cgtgtagtgc 180 t 181 <210> 1407 <211> 181 <212> DNA <213> Artificial Sequence <400> 1407 ttacctgaaa acattcatgt aactatacca gagattagag aaatgttttt agaccatgag 60 tttgacctaa ataaaaaagg taagcccgta gctaaaggaa cgtatactga ccctaatact 120 ggttatggta tggagtttgg cgcgggaggt gtccacggag ctgttgaaca gcttattcac 180 a 181 <210> 1408 <211> 181 <212> DNA <213> Artificial Sequence <400> 1408 agagacatga ggggtaaaga ggagaggtca ccatgaatat tttactagaa gaaactgtgg 60 catttaattt gggactgaga gacgccatct ttattagggt gtcagaactt acaaatattg 120 taagggacca cttcacaact tacgtatata gtggcatgct tgttgtctcc aagttagagc 180 a 181 <210> 1409 <211> 181 <212> DNA <213> Artificial Sequence <400> 1409 tcccttggtc tagcgtctta ggtagtcccg cttcatcaca taatagacga attaattcta 60 ctagtagctt atagtctttc ataaactctt ctttggtatt gtgcgattca atcaattcaa 120 ttgccgcata tccccacgag ttccatccgc cacctacgtc ataaaagccc gcgtttgtgc 180 g 181 <210> 1410 <211> 181 <212> DNA <213> Artificial Sequence <400> 1410 agtttcaagg tgcattaggt ctttcacaag agggcgcaga aaactacact caaatggcta 60 acgaactagt tgctgagggt ttgggtagcc ttgaggacat ggttgacgct atgagtaggg 120 ttgagcaaaa cagccctatc cctgtattcg gtgaggacct acagaacctt acacgttacg 180 c 181 <210> 1411 <211> 181 <212> DNA <213> Artificial Sequence <400> 1411 tgtttttctc cctaaaaagc actacacgct gattcctccc aacgtgtagt gctgtttatt 60 attttgacga gttaagttcg tcaattgtgt cattgtatgc agtagctagg ttattcatga 120 ggtcaccaat ttttccaatt atttggtctg gttcattacc ccctaaaagg ttacccatat 180 c 181 <210> 1412 <211> 181 <212> DNA <213> Artificial Sequence <400> 1412 cacttcacaa cttacgtata tagtggcatg cttgttgtct ccaagttaga gcacttggat 60 gagttttcta aattgtcaag aaaacacgga gaagattatg cacttggaat tgtgctaggc 120 tatccgccag agtgtgtgaa ttggtttgtc aatagtagta tagaagaaca tgtaatttgt 180 a 181 <210> 1413 <211> 181 <212> DNA <213> Artificial Sequence <400> 1413 tgccgtcttt gaatgcttga aaaacgtctc ttgttttctg agaaaacata tccctgttgt 60 catctagccg tccgtcaaca atagagatac caatttcttt tactaggtcg ttcaccttat 120 caaggttata tgctccaccg tcaagacccg caagcattgt actaaatgcc tcatctgctg 180 t 181 <210> 1414 <211> 181 <212> DNA <213> Artificial Sequence <400> 1414 taaacaattc tttttcaggg ataggaataa cccacgtaac agcggtcaag tcatttactc 60 gtgctaggtc tataccaata aatacttcac gccctgtgat gtcaaactcc tcgtctgtgt 120 acgccttgtc ccactcgtct acagaaatgt atgacgttgc ttggtccgca acccaaaaat 180 t 181 <210> 1415 <211> 181 <212> DNA <213> Artificial Sequence <400> 1415 ttgatatgtt caaaaccatg cacccacatt tagccaatgt gaatgtaact cagacaaaaa 60 taaatgagtc ccttacctca ttctttgaac gatttgacag tgactacagg caactcaaag 120 cgtggtaccc tatacgcaac caacgaacct ctattctagc tgtatatgca aacaacggtt 180 t 181 <210> 1416 <211> 181 <212> DNA <213> Artificial Sequence <400> 1416 tatggagttt ggcgcgggag gtgtccacgg agctgttgaa cagcttattc acagtggacg 60 ctttctcatg cgtgactacg gtagtttgta ccctaatgtg tatgtgaatt ttgatgttct 120 ttctcgtaac gtacctgagg agaataagca cctagtgaaa gaactcttag ataaacgtct 180 a 181 <210> 1417 <211> 181 <212> DNA <213> Artificial Sequence <400> 1417 atgagtaact cctccttacc tacaggcggt tctactgtac ctgtaacaat aaccggtgtc 60 acttttgctt ttcgccattt attaatcgtt acagtaatca tttatttttc ctccttatta 120 gacattattc ccataggaac atatcatttc ttataacaaa aatatcttct gacttagtat 180 c 181 <210> 1418 <211> 181 <212> DNA <213> Artificial Sequence <400> 1418 ttaataattt attagccatc ttcgcactcg gtttttctac ctcaatgaag ttactaggtt 60 ctaaataagc tttaccgttg tcagaggtat atacctctaa tgtgtcacct gtgttaggga 120 caccacccat tttgtttagg tcctcgttaa atcgctctgt aacctcatct tttttagtcc 180 a 181 <210> 1419 <211> 181 <212> DNA <213> Artificial Sequence <400> 1419 tcccactcgt ctacagaaat gtatgacgtt gcttggtccg caacccaaaa attcagctcc 60 ttagttagga agttggtgag attaccttta gcctctccct ctgtcttttt agcccgtttg 120 tgttctaaca tatgtgtgcg aacgtcaggt ttttcaaaaa gagggttaga tttaaaccag 180 t 181 <210> 1420 <211> 181 <212> DNA <213> Artificial Sequence <400> 1420 caaggttacc taaatcattt ttagcaatct taacaataac aaactcatcc tcaacttcat 60 cctgttcccc atccacgcgt atagtcactt tcttttctag ttcttgctcc tgtaaacgca 120 ttccctcagc gcgtactttc tcatattgct gtactgcctc cattaggtct aaaccgttgt 180 t 181 <210> 1421 <211> 181 <212> DNA <213> Artificial Sequence <400> 1421 aaatttttct caagtctcta agttgtgcgt ctgttaagtg tacgcttact acatcattcg 60 taatatcagt aattttaatc actgttttat ctttatataa cctagcgaca ctcaaggtag 120 caccttggtt atctttcaat ctatattcaa ttccctcatt aacatagtca cgttcaaaac 180 g 181 <210> 1422 <211> 181 <212> DNA <213> Artificial Sequence <400> 1422 atattcaaac gggaacatgc gagtgttgtt taacgactca tcaactaaca gaagagtcta 60 ttatagcaat gacttattaa ccaactactt gccagcagga gttaaatatt ccgtcacaat 120 agacgcagtc agcaacaata atgggttaat tagggtaggt aattttgacg ctctcagtac 180 a 181 <210> 1423 <211> 181 <212> DNA <213> Artificial Sequence <400> 1423 cggaaaaact tcccttggat aaaggtgata gcgtgtaagg aggtcaatga cctacttgtt 60 tcaaaaggta aggcacccgt taacattata gtggaacacg gtaccactat tgacgtgagt 120 ggcgtagtgt gtacgttttt agacgctcct catgaggttc aaaacttagg cattatcgga 180 a 181 <210> 1424 <211> 181 <212> DNA <213> Artificial Sequence <400> 1424 gatactaagt cagaagatat ttttgttata agaaatgata tgttcctatg ggactaatgt 60 ctaataagga ggaaaaataa atgattactg taacgattaa taaatggcga aaagcaaaag 120 tgacacctgt tattgttaca ggtacagtag aaccgcctgt aggtaaggag gagttactca 180 t 181 <210> 1425 <211> 181 <212> DNA <213> Artificial Sequence <400> 1425 tacagcaccg tcatagttag cctctaggag taacaaatca attttcttac ctgttttatc 60 aaggtactca ctgaatgcca cagtagtcat taggtctgta gcgtataaaa aactttgacc 120 gtttgagttt ccgataatgc ctaagttttg aacctcatga ggagcgtcta aaaacgtaca 180 c 181 <210> 1426 <211> 181 <212> DNA <213> Artificial Sequence <400> 1426 ataggacttt catttaaagt attaaaaaaa gatttacagg actgtcactt actgtttata 60 agtcacattc atggagacca cctgaatgtt ggttgttata accaaatacg gaaaaacttc 120 ccttggataa aggtgatagc gtgtaaggag gtcaatgacc tacttgtttc aaaaggtaag 180 g 181 <210> 1427 <211> 181 <212> DNA <213> Artificial Sequence <400> 1427 caattcagaa gaacaaacag agtatgattg ggtgtgatta gatgattgaa tataagatta 60 taagcagtgg gtcagtaggt aacgcggtta aattaacatt tcagaatggt ataaaaatga 120 tgattgagat aggactttca tttaaagtat taaaaaaaga tttacaggac tgtcacttac 180 t 181 <210> 1428 <211> 181 <212> DNA <213> Artificial Sequence <400> 1428 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc tgactgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata 180 t 181 <210> 1429 <211> 181 <212> DNA <213> Artificial Sequence <400> 1429 aaatttttct caagtctcta agttgtgcgt ctgttaagtg tacgcttact acaacattcg 60 taaaatcagt aattttaatc actgttttat ctttatataa cctagcgaca ctcaaggtag 120 caccatgttt atctttcaaa ctatattcaa ttccctcatt aacatagtca cgttcaaaac 180 g 181 <210> 1430 <211> 181 <212> DNA <213> Artificial Sequence <400> 1430 ggatatgttt tctcagaaaa caagagacgt ttttcaagca ttcaaagacg gcacagcgac 60 acaggctgat gttactcaaa gtatgctaaa cgacttctca aaaatggact ctagttatga 120 atcacttaac aaagcctcta cagtgtggag cgcgctaggt gaggacaaca gtatgaaaat 180 g 181 <210> 1431 <211> 181 <212> DNA <213> Artificial Sequence <400> 1431 atgagtaact cctccttacc tacaggcggt tctactgtac ctgtaacaat aaccggtgtc 60 acttttgctt ttcgccattt attaatcgtt acagtaatca tttatttttc ctccttatta 120 gacattagtc ccataggaac atatcatttc ttataacaaa aatatcttct gacttagtat 180 c 181 <210> 1432 <211> 181 <212> DNA <213> Artificial Sequence <400> 1432 ctttcattaa ggtagtaaaa gagtgtattc cgtttgcttt accttttacg tcacagtcta 60 ctactaataa tttgttttgg tccccacata agaccccttt attcatgttt cttattttac 120 ctaatgtatt gtaactctct tgagcttgcc actcttttat cgcgggaatt ttagtacgcg 180 c 181 <210> 1433 <211> 181 <212> DNA <213> Artificial Sequence <400> 1433 ctagaacaaa atgaccatgc taccccgttc atccaacaca ttacagaacg tgggaaacta 60 tatacgtggt attcaattgg cacaggacta gacgcgtcta caattccaat gactcgcacc 120 acgcaaacat ataccattca aaatgaagct actaaagttc tcagattgag cctaaatgta 180 t 181 <210> 1434 <211> 181 <212> DNA <213> Artificial Sequence <400> 1434 aaatttttct caagtctcta agttgtgcgt ctgttaagtg tacgcttact acaacattcg 60 taaaatcagt aattttaatc actgttttat ctttatataa cctagcgaca ctcaaggtag 120 caccatgatt atctttcaaa ctatattcaa ttccctcatt aacatagtca cgttcaaaac 180 g 181 <210> 1435 <211> 180 <212> DNA <213> Artificial Sequence <400> 1435 gcaacaccac caaatgtaac aggtggtcaa tacctatgga cacgtattat ctggacattt 60 acagataata gtaaccaaac aacctcctca gtggcgcgct ttggtcagga tggtattagt 120 gtgactggta ctcaatcaga gtatgtacaa acaactagtt ctgtagaacc tacctcagga 180 <210> 1436 <211> 180 <212> DNA <213> Artificial Sequence <400> 1436 gtagctcagt ggcgtctacg tctttccaac aataagcaac ctctttgcgt aggtcctcat 60 ctgttagttt accgccttgt tcaaagtcaa catccgtctc tttgacttct aaccccatga 120 aaccctcatg ttctttcagt gaaaaccctt tgtgttcatg gtacaggtca caacctagaa 180 <210> 1437 <211> 180 <212> DNA <213> Artificial Sequence <400> 1437 gggaatacag gtgtcatttc tcacgcatat gcaacggcac atcaaccaaa caatggttct 60 gaccatattg acccctatcc atacttgcgt aaatggggaa ttagtaaaga gcagtttgct 120 aaagacaata aaaatgggtt tggtggaaat agttccaata ctgacaacaa acctaaacca 180 <210> 1438 <211> 180 <212> DNA <213> Artificial Sequence <400> 1438 gacggtaata cacctacagt agacaatact agccctacat atgtagggta tagtaccacg 60 gacactgtac ctgaggacac tgcgccaaat atcctattaa acggttcaca ggacaatagt 120 atacagtctt ggggaatctt tgacgcagta acggctacac caacagcagg agccactaaa 180 <210> 1439 <211> 180 <212> DNA <213> Artificial Sequence <400> 1439 cgtatctcag agcctctcag agcgttttag agcatgtttg tttttgagcg taaaaaagag 60 agggttcttt ccctctcaat ttgtttctat tactgtttgg atgttcttgt ttgttgtgac 120 aagaaaaaca aatactttct aaataattca tatctaacct atgttcccat ccctcagagg 180 <210> 1440 <211> 180 <212> DNA <213> Artificial Sequence <400> 1440 ttacctttta caaagtttgg cactggttga cccgtttggt atttagttgc tttggcgcgt 60 acttttactt tactacctac agggaaatca cgtgtgtctg tgatttttgg tttagacggt 120 tgtggttgtg gtttaggttt gttgtcagta ttggaactat ttccaccaaa cccattttta 180 <210> 1441 <211> 180 <212> DNA <213> Artificial Sequence <400> 1441 actacgttta cttcataatt aaaagcaggt tgacttttct ttttcaattc actaacagca 60 agtgaagcca atttaccttt atccagggtg tcatacgtta cagcacgtgt gaacaaacct 120 cctgttgttg ataagagtct ggaccattta ggagcttctt gcgtgtcaat cataacccca 180 <210> 1442 <211> 180 <212> DNA <213> Artificial Sequence <400> 1442 tgctgaggaa tttagcaaac gcgtaccata ctggtctaac agtaaagcaa aaatgagcgg 60 taagcgtggt tcatatatgg gtgagcatat gagagaccat gttatctata gcaaagccaa 120 agatggagat gtagaaattg gctttgatga tgaggttgcg tggcgcgcgc actttattga 180 <210> 1443 <211> 180 <212> DNA <213> Artificial Sequence <400> 1443 atgatgtact gtgttccttt aatttctaac acacctatga gattattact tgtgttctta 60 gttaccttat aattgacagc attactagca ccccattctg gtacagaaac ccctgttgtt 120 cgtgtaattt cactagttcc gtcagacact agtgttggtt gttcagattg cccactaggt 180 <210> 1444 <211> 180 <212> DNA <213> Artificial Sequence <400> 1444 aggagctgat taacacatgg tgcaaagcgg aaaaccagta ggaaatatga agattggttt 60 aggtattgac ggaaccgctg aactaggtaa tacacttgac aaactaacaa aacaattcaa 120 acaagctgaa agctccatga aggcaaacat caaagcgttt gacggtgcct ctgatagtgt 180 <210> 1445 <211> 180 <212> DNA <213> Artificial Sequence <400> 1445 ccgcgtgagt tagtaatcat tagtagaatt ttagtcattt ttcttaccct caccatatcc 60 gtcaaggtat gccactgcct cacgtatcgt tgtatcatgt ttaatcttgt ctctaaactc 120 ctcagcgtca atcattactt tgctatcatc tgtcttctca tagggttcta gaggctccat 180 <210> 1446 <211> 180 <212> DNA <213> Artificial Sequence <400> 1446 tctcatgaca atgttccagt agtattgaaa cgattgaggt gacgtggttt taatagcagg 60 tacaacatta ttaagtaagt caagtgcacc atcttcacaa cttatctcac gtgttcccgc 120 caatggggtg tgtgtgaagt ccatgatagt aagacaggca ctatctccgt tatgtcgtct 180 <210> 1447 <211> 180 <212> DNA <213> Artificial Sequence <400> 1447 gttactccta gaggctaact atgacggtgc tgtaattggt tatagtgaat atatgaaaat 60 tcacagcggt tatgatacgt ataataatgg ttcctataga catttgtcag ttcgccaaaa 120 tacagaggtc gccactaaat acttgtcaga gggtggtacg agtattcatt tacaccagag 180 <210> 1448 <211> 180 <212> DNA <213> Artificial Sequence <400> 1448 ttctaggttg tgacctgtac catgaacaca aagggttttc actgaaagaa caggagggtt 60 tcatggggtt agaagtcaaa gagacggatg ttgactttga acaaggcggt aaactaacag 120 atgaggaact acgcaaagag gttgcttatt gttggaaaga cgtagacgcc actgagctac 180 <210> 1449 <211> 180 <212> DNA <213> Artificial Sequence <400> 1449 ttggggaatc tttgacgcag taacggctac accaacagca ggagccacta aagtaactaa 60 aacagcagtg tcaacaatac gtcctgcata cctatcaaat ggctacagtg ctttgcgcgg 120 tacaacgtac actgtatcag ggagtgtatt catctctaag gggtggactg gtagtctagc 180 <210> 1450 <211> 180 <212> DNA <213> Artificial Sequence <400> 1450 tctcatgaca atgttccagt agtattgaaa cgattgaggt gacgtggttt tattagcagg 60 tacaacatta ttaagtaagt caagtgcacc atcttcacaa cttatctcac gtgttcccgc 120 caatgggttg tgtgtgaagt ccatgatagt aagacaggca ctatctccgt tatgtcgtct 180 <210> 1451 <211> 180 <212> DNA <213> Artificial Sequence <400> 1451 gttactccta gaggctaact atgacggtgc tgtaattggt tatagtgaat atctgaaaat 60 tcacagcggt tatgatacgt ataataatgg ttcctataga catttgtcag ttcgccaaaa 120 tacagagttc gccactaaat acttgtcaga gggtggtacg agtattcatt tacaccagag 180 <210> 1452 <211> 180 <212> DNA <213> Artificial Sequence <400> 1452 cttcatattt cctactggtt ttccgctttg caccatgtgt taatcagctc ctattttctc 60 tagcttttca agttcctcag gacttaagaa acgcttaata aagtcagcgc catccatcac 120 cttttcttgt ttagactctt taccaaacaa ttgtaataaa agaaagtagt cagcgttctc 180 <210> 1453 <211> 180 <212> DNA <213> Artificial Sequence <400> 1453 tctaattatc tattactttt tcccaaacat atgttacgcc actctggtag cgctctttca 60 tatagttatc aacaatttcg cctatattgt ctgagtttct gaccataatg gtctctagaa 120 acaaatcccc gcgtgagtta gtaatcatta gtagaatttt agtcattttt cttaccctca 180 <210> 1454 <211> 180 <212> DNA <213> Artificial Sequence <400> 1454 tcaataaagt gcgcgcgcca cgcaacctca tcatcaaagc caatttctac atatccatct 60 ttggctttgc tatagataac atggtctctc atatgctcac ccatatatga accacgctta 120 ccgctcaatt ttgctttact gttagaccag tatggtacgc gtttgctaaa ttcctcagca 180 <210> 1455 <211> 180 <212> DNA <213> Artificial Sequence <400> 1455 tcaattatat tctcaacttc atttaataag tcctcgttaa caacaatttg ctgtactacg 60 taaagcgcgt atagtgctaa gtcagtaggt gagtcaccgt caataaatac agtatcaata 120 acaatagaca cagtaactaa accactgaag acaagtaact cagcagactc aatacccgtt 180 <210> 1456 <211> 180 <212> DNA <213> Artificial Sequence <400> 1456 ctctggtgta aatgaatact cgtaccaccc tctgacaagt atttagtggc gacctctgta 60 ttttggcgaa ctgacaaatg tctataggaa ccattattat acgtatcata accgctgtga 120 attttcagat attcactata accaattaca gcaccgtcat agttagcctc taggagtaac 180 <210> 1457 <211> 180 <212> DNA <213> Artificial Sequence <400> 1457 ttctaggttg tgacctgtac catgaacaca aagggttttc actgaaagaa caggagggtt 60 tcatggggtt agaagtcaaa gagacggatg ttgactttga acaaggcggt aaactaacag 120 atgaggacct acgcaaagag gttgcttatt gttggaaaga cgtagacgcc actgagctac 180 <210> 1458 <211> 180 <212> DNA <213> Artificial Sequence <400> 1458 tctcatgaca atgttccagt agtattgaaa cgattgaggt gacgtggttt tattagcagg 60 tacaacatta ttaagtaagt caagtgcacc atcttcacaa cttatctcac gtgttcccgc 120 caatggggtg tgtgtgaagt ccatgatagt aagacaggca ctatctccgt tatgtcgtct 180 <210> 1459 <211> 180 <212> DNA <213> Artificial Sequence <400> 1459 tcaataaagt gcgcgcgcca cgcaacctca tcatcaaagc caatttctac atctccatct 60 ttggctttgc tatagataac atggtctctc atatgctcac ccatatatga accacgctta 120 ccgctcaatt ttgctttact gttagaccag tatggtacgc gtttgctaaa ttcctcagca 180 <210> 1460 <211> 179 <212> DNA <213> Artificial Sequence <400> 1460 agacaaccct agttgggttg cctcgttcgt ttattacagt ccaaaaccaa actcaccgct 60 tgcgtaacgt tctgaccagt ttatttcctc gaactcataa aagtatgctt cactgtacgc 120 gtttataagc gcgtcaagag ggtcaatctt gttgcggtta acttgtttat caatcataa 179 <210> 1461 <211> 179 <212> DNA <213> Artificial Sequence <400> 1461 ttgaacaaag taatagcttg ttctaagtca ccaatgaata atagtttatc atttgtgtcg 60 attttaaaga tagcgtcagg aagtacaatt acctctttac caaacaatgt tttaccactt 120 gccattgcta cgtttggttg aataatgtat cgtccgtctg cgtctttcaa cgtatccaa 179 <210> 1462 <211> 179 <212> DNA <213> Artificial Sequence <400> 1462 cccttgcata agcgagggtt ttattatata ctagtgaacg agggggatga aattaatgaa 60 cactattttc acaccaacta agcaacaaaa agagaacgcg cgtaccatgt ttgaactttg 120 gaaaacagta gaaggtaacg ccatgagtta tgaccccatg acagggggaa taaaagagg 179 <210> 1463 <211> 179 <212> DNA <213> Artificial Sequence <400> 1463 gcgttttaaa cttgagaatg gggttatgat tgacacgcaa gaagctccta actggtccag 60 actcttatca acaacaggag gtttgttcac acgtgctgta acgtatgaca cccttgataa 120 aggtaaattg gcttcacttg ctgttagtga attgaaaaag aaaagtcaac ctgctttta 179 <210> 1464 <211> 179 <212> DNA <213> Artificial Sequence <400> 1464 ctactgcgtt atcttgagtg ctatatccgt ttagttcata aatgaggtcg tccatggcta 60 acgcgttgcc atggaactcc tcctctagaa ctctgttaaa cagcatattt aactcatcat 120 caaacccctt accgtttaat accttgttaa tatactccgt tttaaattgc tctaacata 179 <210> 1465 <211> 179 <212> DNA <213> Artificial Sequence <400> 1465 tgtaaaatca ggtttccaat tcattaagta agaaacagcc tccctacctg tgcgtgtctc 60 acggagtttc aggcgtctca ttgggttacc ttttttagat tgtgtttcaa tgttctctgt 120 aacaacaccc tcttttattc cccctgtcat ggggtcataa ctcatggcgt taccttcta 179 <210> 1466 <211> 179 <212> DNA <213> Artificial Sequence <400> 1466 ttacgcgcgc gttagagcca tccattggga aaattttcaa acgcacgtac aatttggctt 60 tgtgtacaat tcccgtttcc tttacagcct ccttttcttt cagttcaaat tttgactcaa 120 tatattcctc atggtcaaaa ataaaataca tattatgcat atctgtcaaa acatatagt 179 <210> 1467 <211> 179 <212> DNA <213> Artificial Sequence <400> 1467 gcgttttaaa cttgagaatg gggttatgat tgacacgcaa gaagctccta aatggtccag 60 actcttatca acaacaggag gtttgttcac acgtgctgta acgtatgaca cccttgataa 120 aggtaaagtg gcttcacttg ctgttagtga attgaaaaag aaaagtcaac ctgctttta 179 <210> 1468 <211> 179 <212> DNA <213> Artificial Sequence <400> 1468 agtgcgcaag gatggtgcaa ttctagtaag taggtatggt actacagtag atagtgcgat 60 tccgtcaggc gcatggataa acatctcttg cgtatatgcg ggtcaagatt tattctaagg 120 gggataagta tgttagagca atttaaaacg gagtatatta acaaggtatt aaacggtaa 179 <210> 1469 <211> 179 <212> DNA <213> Artificial Sequence <400> 1469 tttggttttg gactgtaata aacgaacgag gcaacccaac tagggttgtc tgtttcgtgt 60 tataatttat aaagaagtta taattggagg aggttcacca tggaacgaat tatatattta 120 cctatgatta tgtatatact agcgtgtgtt tttatggcta ttggtgcctt tttggtaga 179 <210> 1470 <211> 179 <212> DNA <213> Artificial Sequence <400> 1470 taaaagcagg ttgacttttc tttttcaatt cactaacagc aagtgaagcc actttacctt 60 tatcaagggt gtcatacgtt acagcacgtg tgaacaaacc tcctgttgtt gataagagtc 120 tggaccagtt aggagcttct tgcgtgtcaa tcataacccc attctcaagt ttaaaacgc 179 <210> 1471 <211> 179 <212> DNA <213> Artificial Sequence <400> 1471 ctgactctcg tctgtttcag gataaccata gtaggcgcgt acctcgttag gtttaagata 60 ctcaatgcct ttggctgtac cctcaaacat tcgtttgttg cgttcgtcta atgtatcgtt 120 taataaacta gcaaagtcta ggtccacgtc aatatttaat ttaagattta tctcatcac 179 <210> 1472 <211> 178 <212> DNA <213> Artificial Sequence <400> 1472 taattatacc taaaccttgt ttagacccct cagaagccca atcagacacc atagacgcaa 60 ggcacactac tacgagtttc tttagccctg attttttaaa cgattctaat gccatgagtg 120 tcttgcctga gccaacctca ctatgattta gattatgtgt ttcccatttg tctatgac 178 <210> 1473 <211> 178 <212> DNA <213> Artificial Sequence <400> 1473 ctcagtagcc acaagggagg tagtggataa ggtaacatgg acaatgaaat ctaaggaagt 60 cctacacatt cgtgcaggtt ccaagactag ttacaagtca tacggtctgt tacctaaggg 120 cgtcacgatt gaaacaacca aacgtcaaac gggtcaaaag attattaaaa acaaccaa 178 <210> 1474 <211> 178 <212> DNA <213> Artificial Sequence <400> 1474 gaatagctcc taatttgaac attaagcccg cctttgtgtc tgtagctact acgtcaaaac 60 ggatggcacc cgctaacatt tcaccgtaga cattgtggtc ttgccaacgt accgtcattt 120 cagtacgatt gaacaaagta atagcttgtt ctaagtcacc aatgaataat agtttatc 178 <210> 1475 <211> 178 <212> DNA <213> Artificial Sequence <400> 1475 aggctgtaaa ggaaacggga attgtacaca aagccaaaat gtacgtgcgt ttgaaaattt 60 tcccaatgga tggctctaac gcgcgcgtaa acgaaccact cctacatttc tttctcagtt 120 tttatgagta tgcagacacc tcaacatgga gaggcaaaga agttttcata caagggtg 178 <210> 1476 <211> 178 <212> DNA <213> Artificial Sequence <400> 1476 taacaattga ccctgcttac aatcaacgag tttttgtttc tcaaagcgca tttgctcaat 60 tggatacgtt gaaagacgca gacggacgat acattattca accaaacgta gcaatggcaa 120 gtggtaatac attgtttggt aaagaggtaa ttgtacttcc tgacgctatc tttaaaaa 178 <210> 1477 <211> 178 <212> DNA <213> Artificial Sequence <400> 1477 tggatacgtt gaaagacgca gacggacgat acattattca accaaacgta gcaatggcaa 60 gtggtaaaac attgtttggt aaagaggtaa ttgtacttcc tgacgctatc tttaaaaacg 120 acacaaaaga taaactatta ttcattggtg acttagaaca agctattact ttgttcaa 178 <210> 1478 <211> 178 <212> DNA <213> Artificial Sequence <400> 1478 atttttgcaa caatagagta ggtctctttc ttcttgtgtt ccacacgttt agtgttttgt 60 aggtaatatc cactgaccca tcctgaggca ggtattttct tacctgagtt cttagttaca 120 taataccctt ggttgttttt aataatcttt tgacccgttt gacgtttggt tgtttcaa 178 <210> 1479 <211> 178 <212> DNA <213> Artificial Sequence <400> 1479 cacccttgta tgaaaacttc tttgcctctc catgttgagg tgtctgcata atcataaaaa 60 ctgagaaaga aatgtaggag tggttcgttt acgcgcgcgt tagagccatc cattgggaaa 120 attttcacac gcacgtacat tttggctttg tgtacaattc ccgtttcctt tacagcct 178 <210> 1480 <211> 178 <212> DNA <213> Artificial Sequence <400> 1480 agtctatgat agcaatgact tattaaccac ctacttgcca gcaggagtta tatattccgt 60 cacaatagac gcattcagca acattaatgg gataattagg gttggtaatt ttgacgatct 120 cagttcatgg caaacaataa aactaggtga cacaccttca acgtataaat ttgagggt 178 <210> 1481 <211> 178 <212> DNA <213> Artificial Sequence <400> 1481 tttttaaaga tagcgtcagg aagtacaatt acctctttac caaacaatgt tttaccactt 60 gccattgcta cgtttggttg aataatgtat cgtccgtctg cgtctttcaa cgtatccaat 120 tgagcaactg cgctttgaga aacaaaaact cgttgattgt aagcagggtc aattgtta 178 <210> 1482 <211> 178 <212> DNA <213> Artificial Sequence <400> 1482 tttttaaaga tagcgtcagg aagtacaatt acctctttac caaacaatgt attaccactt 60 gccattgcta cgtttggttg aataatgtat cgtccgtctg cgtctttcaa cgtatccaat 120 tgagcaactg cgctttgaga aacaaaaact cgttgattgt aagcagggtc aattgtta 178 <210> 1483 <211> 178 <212> DNA <213> Artificial Sequence <400> 1483 aggctgtaaa ggaaacggga attgtacaca aagccaaaat gtacgtgcgt gtgaaaattt 60 tcccaatgga tggctctaac gcgcgcgtaa acgaaccact cctacatttc tttctcagtt 120 tttatgagta tgcagacacc tcaacatgga gaggcaaaga agttttcata caagggtg 178 <210> 1484 <211> 178 <212> DNA <213> Artificial Sequence <400> 1484 gtcatagaca aatgggaaac acataatcta aatcatagtg aggttggctc tggcaagaca 60 ctcatggcat tagaatcgtt taaaaaatca gggctaaaga aactcgtagt agtgtgcctt 120 gcgtctatgg tgtctgattg ggcttctgag gggtctaaac aaggtttagg tataatta 178 <210> 1485 <211> 177 <212> DNA <213> Artificial Sequence <400> 1485 agggaccatg ttaccatgtt acagagcaac acagactgtc acgcctacag tcctcatgat 60 gaggaggctg aacgtattac agacgcgttc tgtgatgaca tttctgagcg cgtaggtatt 120 gtattggaca aagatgagtt cattgcctta taccagaaag atgtcaacaa ttatatt 177 <210> 1486 <211> 177 <212> DNA <213> Artificial Sequence <400> 1486 tagtagtgtg ccttgcgtct aaggtgtctg attgggcttc tgaggggtct aaacaaggtt 60 taggtataat taccctaagt gggtctccaa agctcagagg agagcttcta gaggcgtcag 120 gaacgcacta tgtatcaatc agctttcaat catcatggcg aacacctgaa ttattga 177 <210> 1487 <211> 177 <212> DNA <213> Artificial Sequence <400> 1487 taggtggacg gtcttataat gcgattgtgg gatatagaaa cactgaggac ttaaatgagc 60 tactcaaaga acacagcgtt gctattaaac gtgacaacaa actcatccca tcagatattg 120 tgtataaagt caagtcacca tcaatggtta agaaactacg cacacataga gtatatg 177 <210> 1488 <211> 177 <212> DNA <213> Artificial Sequence <400> 1488 ttaaattgag ggttaccttt gacaagttcg tataccttgt ccccaacttg acctaagaac 60 gtacctactt tattatcact atcaccactt ttaaactctt gcgcttgtgg gtaaatgaca 120 gagtatagta gaaattcacg tacattatta gaaacatagt gccaaatgtt cgtatct 177 <210> 1489 <211> 177 <212> DNA <213> Artificial Sequence <400> 1489 tgaggtcacc aatttttcca attatttggt ctggttcatt accccctaac aggttaccca 60 tatctaccgc atcgcagacg tcaatcatct gtgtaatagc actctttaca attcctgact 120 ctagaatgtc aaaccccaca gcgtgtgcgt gcagtacatt gtaagcaaac attagac 177 <210> 1490 <211> 177 <212> DNA <213> Artificial Sequence <400> 1490 tcctcagtgt ttctatatcc cacaatcgca ttataagacc gtccacctac atactgtttc 60 tcttctatac agtagcgttc tctaaaagat ttccacgttc cagagtataa acctgcgatt 120 ttcaattgag aaaaccattg ttctaacatt ccgttagaaa ttggagttcc gctcatt 177 <210> 1491 <211> 177 <212> DNA <213> Artificial Sequence <400> 1491 gtgctgtttg ttatagaccc ttcgtttgta ggtacgtttt acgtaaaaat ctttaaacta 60 gaacaaaatg accatgctac cccgttcatc caacacatta cagaacgtgg taaactatat 120 acgtggtatt caattggcac aggactagac gcgtctacaa ttccaatgac tcgcacc 177 <210> 1492 <211> 177 <212> DNA <213> Artificial Sequence <400> 1492 atacccctgt ttggaatatt gtctataggg tgttctatcg ttagcctctt tctgaacaat 60 accaccaccc gttgttgcta cccacgcgtg agagtcaaca ataaacaatt ctttttcagg 120 gataggacta acccacgtaa cagcggtcaa gtcatttact cgtgctaggt ctatacc 177 <210> 1493 <211> 177 <212> DNA <213> Artificial Sequence <400> 1493 gtgctgtttg ttatagaccc ttcgtttgta ggtacgtttt acgtaaaaaa ctttaaacta 60 gaacaaaatg accatgctac cccgttcatc caacacatta cagaacgtgg taaactatat 120 acgtggtctt caattggcac aggactagac gcgtctacaa ttccaatgac tcgcacc 177 <210> 1494 <211> 177 <212> DNA <213> Artificial Sequence <400> 1494 ttactaagga agggtggttg atttacgagg accttgttcc acaacttaat cagctaccaa 60 tttcaaaact agacgctggc atgctagtca tttattgtaa tacttacgct atttacagtc 120 aggcaactca agaggtatct gaatacggtt atcttgacga aaaagggaaa ccatcag 177 <210> 1495 <211> 177 <212> DNA <213> Artificial Sequence <400> 1495 tccgctcatt aaataggtgt gtcctgcttt cttacttact ttcatccaaa acttagttac 60 gtttgcgctc ctgtttgcta gacagtgaga ctcatcaaaa acaatcatag tgtctttatc 120 tataaatgtc aataattcag gtgttcgcca tgatgattga aagctgattg atacata 177 <210> 1496 <211> 177 <212> DNA <213> Artificial Sequence <400> 1496 tattaatcgc gggtattgca ttatatgaac ttctttacga acgttcgccc atggcgtccc 60 gtcaaatata ttctacagcc aatacaaaag accaagcgtc tatttgtttc cgcatgatta 120 agacacaact acaggctgtt agaaagaaat ctaaaaaggt tcgtgagttt acaaaag 177 <210> 1497 <211> 177 <212> DNA <213> Artificial Sequence <400> 1497 ggtatagacc tagcacgagt aaatgacttg accgctgtta cgtgggttat tcctatccct 60 gaaaaagaat tgtttattgt tgactctcac gcgtgggtag caacaacggg tggtggtatt 120 gttcagacag aggctaacga tagaacaccc tatagacaat attccaaaca ggggtat 177 <210> 1498 <211> 177 <212> DNA <213> Artificial Sequence <400> 1498 taaaattgcc tattaataca ttgtttggtg ccacaggtgc agagtttaat gggttatatg 60 acccacgttt tcaatttcta acatgtgtga ttgggcaatt aattatggct gacttctacg 120 agggaatgag ggaccatgtt accatgttac agagcaacac agactgtcac gcctaca 177 <210> 1499 <211> 177 <212> DNA <213> Artificial Sequence <400> 1499 ttattataca ttgtttttct ccctaaaaag cactacacgc tgattcctcc caacgtgtag 60 tgctttttat tattttgacg agttaagttc gtcaattgtg tcattgtatg cagtagctag 120 gttattcctg aggtcaccaa tttttccaat tatttggtct ggttcattac cccctaa 177 <210> 1500 <211> 177 <212> DNA <213> Artificial Sequence <400> 1500 atacccctgt ttggaatatt gtctataggg tgttctatcg ttagcctctg tctgaacaat 60 accaccaccc gttgttgcta cccacgcgtg agagtcaaca ataaacaatt ctttttcagg 120 gataggacta acccacgtaa cagcggtcaa gtcatttact cgtgctaggt ctatacc 177 <210> 1501 <211> 177 <212> DNA <213> Artificial Sequence <400> 1501 gtgctgtttg ttatagaccc ttcgtttgta ggtacgtttt acgtaaaaat ctttaaacta 60 gaacaaaatg accatgctac cccgttcatc caacacatta cagaacgtgg taaactatat 120 acgtggtctt caattggcac aggactagac gcgtctacaa ttccaatgac tcgcacc 177 <210> 1502 <211> 176 <212> DNA <213> Artificial Sequence <400> 1502 atctacgtca cgcccaacac gtagagtaat atctttctcg tcccccatct cctctacaat 60 gttcattgtt ttacttttta actgcatgtt ttcaaactca aagtcaatgg taaacttagc 120 gcctccaaag tctgaaataa tactccttag acgctccact gctgttgtct cattat 176 <210> 1503 <211> 176 <212> DNA <213> Artificial Sequence <400> 1503 ctatcgctgt tacttacgct gtaggtacct caggtacaac agcaccatcc acaggttggc 60 aagcaacacc accaaatgta acaggtggtc aatacctatg gacacgtatt atctggacat 120 ttacagagaa tagtaaccaa acaacctact cagtggcgcg ctttggtcag gatggt 176 <210> 1504 <211> 176 <212> DNA <213> Artificial Sequence <400> 1504 tttgacttct aaccccatga aaccctcatg ttctttcagt gaaaacccat tgtgttcatg 60 gtacaggtca caacctagaa taggagtttt cttcgtgtta aagagtttat aaataagtcc 120 tctatcatct gacttaataa cagcctgtga caactgaaac gcgtctttac cttgta 176 <210> 1505 <211> 176 <212> DNA <213> Artificial Sequence <400> 1505 tctatagtcc catggttcaa acggacgtag ttctaatgta cgcatgttta gcgcaccgtt 60 ttgaaaatac gcacattcac caaggtatct gtacttatcg ttcgttctat cgttgaaata 120 tccctcatta aattgagggt tacctttgac aagttcgtat accttgtccc caactt 176 <210> 1506 <211> 176 <212> DNA <213> Artificial Sequence <400> 1506 gtttagcctc aagtgcgccc gctgagtccc ctgcgtcttt tagtgctttt acttgttgtt 60 gagtctcacg ttcgttctgt ttcatttctt tagaaagttg tgttagtcca ctcttagcgt 120 caatgtagtc cttggaggtt ttttctagtt gactagttaa accattgtat tttgct 176 <210> 1507 <211> 176 <212> DNA <213> Artificial Sequence <400> 1507 atctacgtca cgcccaacac gtagagtaat atctttctcg tcccccatat cctctacaat 60 gttcattgtt ttacttttta actgcatgtt ttcaaactca aagtcaatgg taaacttagc 120 gcctccacag tctgaaataa tactccttag acgctccact gctgttgtct cattat 176 <210> 1508 <211> 176 <212> DNA <213> Artificial Sequence <400> 1508 tttgacttct aaccccatga aaccctcatg ttctttcagt gaaaaccctt tgtgttcatg 60 gtacaggtca caacctagaa taggagtttt cttcgtgtta aagagtttat aaataagtcc 120 tctatcaact gacttaataa cagcctgtga caactgaaac gcgtctttac cttgta 176 <210> 1509 <211> 176 <212> DNA <213> Artificial Sequence <400> 1509 ctactacgtg cgagaagaac ccactgttga cgggtctgcg catatgatag tctgcctcgt 60 tttgcgctgt agatgatgaa ttccccgtac tgtgtacgtg aatttgtcca tacggtctta 120 cccctacgtg tggtaaacct gagcgcattt gtttttcaat tttcattgaa tcattc 176 <210> 1510 <211> 176 <212> DNA <213> Artificial Sequence <400> 1510 gtatttctac tccttaccca caaccacata ccaatttgag gtgttggacg tgttgtactc 60 catcctgagg taggttctac agaactagtt gtttgtacat actctgattg agtaccagtc 120 acactaagac catcctgacc aaagcgcgcc actgagtagg ttgtttggtt actatt 176 <210> 1511 <211> 176 <212> DNA <213> Artificial Sequence <400> 1511 gtttagcctc aagtgcgccc gctgagtccc ctgcgtcttt tagtgcttgt acttgttgtt 60 gagtctcacg ttcgttctgt ttcatttctt tagaaagttg tgttagtcca ctcttagcgt 120 caatgtattc cttggaggtt ttttctagtt gactagttaa accattgtat tttgct 176 <210> 1512 <211> 176 <212> DNA <213> Artificial Sequence <400> 1512 ctactacgtg cgagaagaac ccactgttga cgggtctgcg catatgatcg tctgcctcgt 60 tttgcgctgt agatgatgaa ttccccgtac tgtgtacgtg aatttgtcca tacggtctta 120 cccctacttg tggtaaacct gagcgcattt gtttttcaat tttcattgaa tcattc 176 <210> 1513 <211> 176 <212> DNA <213> Artificial Sequence <400> 1513 ctactacgtg cgagaagaac ccactgttga cgggtctgcg catatgatcg tctgcctcgt 60 tttgcgctgt agatgatgaa ttccccgtac tgtgtacgtg aatttgtcca tacggtctta 120 cccctacgtg tggtaaacct gagcgcattt gtttttcaat tttcattgaa tcattc 176 <210> 1514 <211> 176 <212> DNA <213> Artificial Sequence <400> 1514 tacaaggtaa agacgcgttt cagttgtcac aggctgttat taagtcagtt gatagaggac 60 ttatttataa actctttaac acgaagaaaa ctcctattct aggttgtgac ctgtaccatg 120 aacacaatgg gttttcactg aaagaacatg agggtttcat ggggttagaa gtcaaa 176 <210> 1515 <211> 176 <212> DNA <213> Artificial Sequence <400> 1515 atctacgtca cgcccaacac gtagagtaat atctttctcg tcccccatct cctctacaat 60 gttcattgtt ttacttttta actgcatgtt ttcaaactca aagtcaatgg taaacttagc 120 gcctccacag tctgaaataa tactccttag acgctccact gctgttgtct cattat 176 <210> 1516 <211> 176 <212> DNA <213> Artificial Sequence <400> 1516 agcaaaatac aatggtttaa ctagtcaact agaaaaaacc tccaaggact acattgacgc 60 taagagtgga ctaacacaac tttctaaaga aatgaaacag aacgaacgtg agactcaaca 120 acaagtacaa gcactaaaag acgcagggga ctcagcgggc gcacttgagg ctaaac 176 <210> 1517 <211> 175 <212> DNA <213> Artificial Sequence <400> 1517 tgtggaggag gtaatataat gttaatacca acggaacaac agcaaatggt catagacaaa 60 tgggaaacac ataatctaaa tcatagtgag gttggctctg gcaagacact catggcatta 120 gaatcgttta aaaaatcagg gctaaagaaa ctcgtagtag tgtgccttgc gtcta 175 <210> 1518 <211> 175 <212> DNA <213> Artificial Sequence <400> 1518 gtttatatac ttatgcgttt gttctaagga gtgatacaat gaaatacaac caatttaagg 60 ggtttcctct caaagcgcgt actaaaattc ccgcgataaa agagtggcaa gctcaagaga 120 gttacaatac attaggtaaa ataagaaaca tgaataaagg ggtcttatgt gggga 175 <210> 1519 <211> 175 <212> DNA <213> Artificial Sequence <400> 1519 gtggctcctg ctgttggtgt agccgttact gcgtcaaaga ttccccacta ctgtatacta 60 ttgtcctgtg aaccgtttaa taggatattt ggcgcagtgt cctcaggtac agtgtccgtg 120 gtactatacc ctacatatgt agggctagta ttgtctactg taggtgtatt accgt 175 <210> 1520 <211> 175 <212> DNA <213> Artificial Sequence <400> 1520 ttataatgaa gagtacttag atgataatta cacttttatt aaaaatgtgc tagaaactga 60 taagccacag gctaatatgg tgaatgaaga actgacagat acagcacgtt attcaaccaa 120 ttcaggtcaa caattgtttg acgtcttagc agatgaccta ctaacagatg accaa 175 <210> 1521 <211> 175 <212> DNA <213> Artificial Sequence <400> 1521 acattaggta aaataagaaa catgaataaa ggggtcttat gtggggacca aaacaaatta 60 ttagtagtag actgtgacgt aaaaggtaaa gcaaacggaa tacactcttt tactacctta 120 atgaaagact taggacatga aaccatacct aacaccctaa tggtctatac accgt 175 <210> 1522 <211> 175 <212> DNA <213> Artificial Sequence <400> 1522 agggaatacc caagttaaat cactagcctc aatgtaaatg ctatctgttt ctaagtcaag 60 caatgcctca cgtccaatga gtaactcctc cttacctaca ggcggttcta ctgtacctgt 120 aacaatacca ggtgtcactt ttgcttttcg ccatttatta atcgttacag taatc 175 <210> 1523 <211> 175 <212> DNA <213> Artificial Sequence <400> 1523 tatttttcct cctcaaattt aattagcgta tctaaataca cacgtgcctt ttcaaggtca 60 gtaatgccac ctttttcttt gtggcgttta atgtacttat aaatgttacc aattaagaaa 120 ccctcatctt ggtcatctgt tagtaggtca tctgctaaga cgtcaaacaa ttgtt 175 <210> 1524 <211> 175 <212> DNA <213> Artificial Sequence <400> 1524 gctgacgtat accatcaatc gttctacatg gtatagggtc tctgtggttc tctttctcaa 60 ttaatacttt ctctgtaggt gtcaaatcgt tttccggtag ttcgtacaag actgccccaa 120 ttgggaatgg tgtcgtctcg ttgtttacta actcatatgt tttcaaacta attcc 175 <210> 1525 <211> 175 <212> DNA <213> Artificial Sequence <400> 1525 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagata aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acgtataaat ttgag 175 <210> 1526 <211> 175 <212> DNA <213> Artificial Sequence <400> 1526 agggaatacc caagttaaat cactagcctc aatgtaaatg ctatctgatt ctaagtcaag 60 caatgcctca cgtccaatga gtaactcctc cttacctaca ggcggttcta ctgtacctgt 120 aacaataaca ggtgtcactt ttgcttttcg ccatttatta atcgttacag taatc 175 <210> 1527 <211> 175 <212> DNA <213> Artificial Sequence <400> 1527 gactaccagt ccacccctta gagatgaata cactccctga tacagtgtac gttgtaccgc 60 gcaaagcact gtagccattt gataggtatg caggacgtat tgttgacact gctgttttag 120 ttaatttcgt ggctcctgct gttggtgtag ccgttactgc gtcaaagatt cccca 175 <210> 1528 <211> 175 <212> DNA <213> Artificial Sequence <400> 1528 aactaaccca ttgaggggta aggggtaaaa cctcttacct cttttttatt agataggagt 60 gagataatgc taacaattga ccaaattaaa aataatctac gcattgacca taatatggat 120 gacgagtctt taacaatgtt acaagaaaca gcagtttctt ttttgatggg agcca 175 <210> 1529 <211> 175 <212> DNA <213> Artificial Sequence <400> 1529 gtggagcata tagtgctgtt ttaggtatta ccgcagacga aaatggtctt atgacagtgg 60 ggcaggacac tcaagctcct tatgtctctg ttacttttgt atcagatgac gcagatggta 120 atgaggtata tatgggactg actaaagttc gctttgctca ccctgacgtt gcgtt 175 <210> 1530 <211> 175 <212> DNA <213> Artificial Sequence <400> 1530 aacgcaacgt cagggtgagc aaagcgaact ttagtcagtc ccatatagac ctcattacca 60 tctgcgtcat ctgatacaaa agtaacagag acataaggag cttgagtgtc ctgccccact 120 gtcataatac cattttcgtc tgcggtaata cctaaaacag cactatatgc tccac 175 <210> 1531 <211> 175 <212> DNA <213> Artificial Sequence <400> 1531 tttttagcaa tcttaacaat aacacactca tcctcaactt catcctgttc cccatccacg 60 cgtatagtca ctttcttttc tatttcgtgc tcctgtaaac gcattccctc agcgcgtact 120 ttctcatctt gctgtactgc ctccattagg tctaaaccgt tgtttgcata tacag 175 <210> 1532 <211> 175 <212> DNA <213> Artificial Sequence <400> 1532 tttttagcaa tcttaacaat aacaaactca tcctcaactt catcctggtc cccatccacg 60 cgtatagtca ctttcttttc tatttcttgc tcctgtaaac gcattccctc agcgcgtact 120 ttctcatctt gctgtactgc ctccattagg tctaaaccgt tgtttgcata tacag 175 <210> 1533 <211> 175 <212> DNA <213> Artificial Sequence <400> 1533 gattactgta acgattaata aatggcgaaa agcaaaagtg acacctggta ttgttacagg 60 tacagtagaa ccgcctgtag gtaaggagga gttactcatt ggacgtgagg cattgcttga 120 cttagaatca gatagcattt acattgaggc tagtgattta acttgggtat tccct 175 <210> 1534 <211> 175 <212> DNA <213> Artificial Sequence <400> 1534 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgtagc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgttt 175 <210> 1535 <211> 175 <212> DNA <213> Artificial Sequence <400> 1535 ggaattagtt tgaaaacata tgagttagta aacaacgaga cgacaccatt accaattggg 60 gcagtcttgt acgaactacc tgaaaacgaa ttgacaccta cagagaaagt attaattgag 120 aaagagacac acagagaccc tataccatgt agaacgattg atggtatacg tcagc 175 <210> 1536 <211> 175 <212> DNA <213> Artificial Sequence <400> 1536 gtggagcata tagtgctgtt ttaggtatta ccgcagacga aaatggtctt atgacagtgg 60 ggcaggacac tcaagctcct tatgtctctg ttacttttgt atcagatgac gcagatggta 120 atgaggtcta tatgggactg actaaagttc gctttgctca ccctgacgtt gcgtt 175 <210> 1537 <211> 174 <212> DNA <213> Artificial Sequence <400> 1537 aaggtgcgct tgattaaacc tgaaccaact gaatttttta tgaatgaggg ttacgagcgt 60 gacagggact acgttggaga ggtgttcaga gtagctcata gcgctgaaga aattgacgga 120 caaacgcacc aacttgaact aagtattgat ggtcacctat ggtgggtata tgat 174 <210> 1538 <211> 174 <212> DNA <213> Artificial Sequence <400> 1538 agactgacgt acatcaaaga gtacgtcctc atacccgtct gctagtcttg tggtaattaa 60 ttgagactgt gcagggtcat aacaaatacc ttgtacgtct aaattgtttg tctcaataaa 120 cgccaaatcc caatttaaca tatcctccca atcacactga ccgtcaggac ggga 174 <210> 1539 <211> 174 <212> DNA <213> Artificial Sequence <400> 1539 ttgatagaga cacgatttca gaccgtattg acgatgtatt aggatacagg gaggaaaaca 60 aaatgagtaa agtatttgag gataatttta ctaaacccct accagtgggg acgaaggtgc 120 gcttgattaa acctgaacca actgaatttt ttatgaatga gggttacgag cgtg 174 <210> 1540 <211> 174 <212> DNA <213> Artificial Sequence <400> 1540 ggcaacgcgt tagccatgga cgacctcatt tatgaactaa acggatatag cactcaagat 60 aacgcagtag acacgttaca gaaccaagtt gactacatga gtaaaatgat aaatagacta 120 gcatacactc aaagttagga gcgggaacga atgccaatga atgaggacaa cttt 174 <210> 1541 <211> 174 <212> DNA <213> Artificial Sequence <400> 1541 ctttactgtc caactggcgt tgttttgttt gctacaaagt cttggaattt ctcaagcgtc 60 aacgtctcag acttcacacc agaggcgtat acatatccac gtgagtcact aatagcagac 120 ccctcaagag tatcagtatt agggtcagtg cctccaccct ctgaggtatt caac 174 <210> 1542 <211> 174 <212> DNA <213> Artificial Sequence <400> 1542 tatcctaata catcgtcaat acggtctgaa atcgtgtctc tatcaatccc atactcatct 60 acgagtttag cacctaaagc gcttgccata ataatgttga aagcaagttt ttcctcatct 120 acttttttac cgtatttcaa cttatcaaaa tcaaacttta gttcctgtaa gacg 174 <210> 1543 <211> 174 <212> DNA <213> Artificial Sequence <400> 1543 ggcaactctc agagatagag aacgctgact actttctttt attacacttg tttggtaaag 60 agtctaaaca agaaaaggtg atggatggcg ctgactttat taagcgtttc ttaagtcctg 120 aggaacttga aaagctagag aaaaaaggag ctgattaaca catggtgcaa agcg 174 <210> 1544 <211> 174 <212> DNA <213> Artificial Sequence <400> 1544 ggcaactctc agagatagag aacgctgact actttctttt attacaattg tttggtaaag 60 agtctaaaca agaaaaggtg atggatggcg ctgactttat taagcgtttc ttaagtcctg 120 aggaactaga aaagctagag aaaaaaggag ctgattaaca catggtgcaa agcg 174 <210> 1545 <211> 174 <212> DNA <213> Artificial Sequence <400> 1545 gttgaatacc tcagagggtg gaggcactga ccctaatact gatactattg aggggtctgc 60 tattagtgac tcacgtggat atgtatacgc ctctggtgtg aagtctgaga cgttgacgct 120 tgagaaagtc caagactttg tagcaaacaa aacaacgcca gttggacagt aaag 174 <210> 1546 <211> 174 <212> DNA <213> Artificial Sequence <400> 1546 cttatcaaac gcacttttag ccatgttttt ggcaccgttc cagatgtttt ttacgcctcc 60 tgtaattttg tcaaagaagc cagtaccttt tttgtatgca aacttaggac gtttatgacc 120 taacactggt gcagtttctt ctgctgttaa aacgtgggtt ccttttcgtc ccca 174 <210> 1547 <211> 174 <212> DNA <213> Artificial Sequence <400> 1547 tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattggtgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtt 174 <210> 1548 <211> 174 <212> DNA <213> Artificial Sequence <400> 1548 ttccgctgta caatgacacg tgaccaaacg ggtaagaagt tcacttggaa ctttgagcat 60 atccaatcaa acaacggaat taaaccagtt acaaaaaacc catttaccta caatgcacct 120 gtagcaatca aagcttccgt tgttaaaaca tctagatggc tactcaagta taaa 174 <210> 1549 <211> 174 <212> DNA <213> Artificial Sequence <400> 1549 gtgacgccct taggtaacag accgtatgac ttgtaactag tcttggaacc tgcacgaatg 60 tgtaggactt ccttagattt cattgtccat gttaccttat ccactacctc ccttgtggct 120 actgagtatt tatacttgag tagccatcta gatgttttaa caacggaagc tttg 174 <210> 1550 <211> 174 <212> DNA <213> Artificial Sequence <400> 1550 ggcaacgcgt tagccatgga cgacctcatt tatgaactaa acggatctag cactcaagat 60 aacgcagtag acacgttaca gaaccaagtt gactacatga gtaaaatgat aaatagacta 120 gcatacaatc aaagttagga gcgggaacga atgccaatga atgaggacaa cttt 174 <210> 1551 <211> 174 <212> DNA <213> Artificial Sequence <400> 1551 tgtactgaga gcgtaataat tacctaccct aattaaccca ttattggtgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgt caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtt 174 <210> 1552 <211> 174 <212> DNA <213> Artificial Sequence <400> 1552 ggcaactctc agagatagag aacgctgact actttctttt attacacttg tttggtaaag 60 agtctaaaca agaaaaggtg atggatggcg ctgactttat taagcgtttc ttaagtcctg 120 aggaactaga aaagctagag aaaaaaggag ctgattaaca catggtgcaa agcg 174 <210> 1553 <211> 174 <212> DNA <213> Artificial Sequence <400> 1553 gttgaatacc tcagagggtg gaggcactga ccctaatact gatactcttg aggggtctgc 60 tattagtgac tcacgtggat atgtatacgc ctctggtgtg aagtctgaga cgttgacgct 120 tgagaaagtc caagactttg tagcaaacaa aacaacgcca gttggacagt aaag 174 <210> 1554 <211> 174 <212> DNA <213> Artificial Sequence <400> 1554 ggcaacgcgt tagccatgga cgacctcatt tatgaactaa acggatctag cactcaagat 60 aacgcagtag acacgttaca gaaccaagtt gactacatga gtaaaatgat aaatagacta 120 gcatacactc aaagttagga gcgggaacga atgccaatga atgaggacaa cttt 174 <210> 1555 <211> 174 <212> DNA <213> Artificial Sequence <400> 1555 tggggacgaa aaggaaccca cgttttaaca gcagaagaaa ctgcaccagt gttaggtcat 60 aaacgtccta agtttgcata caaaaaaggt actggcttct ttgacaaaat tacaggaggc 120 gtaaaaatca tctggaacgg tgccaaaaac atggctaaaa gtgcgtttga taag 174 <210> 1556 <211> 173 <212> DNA <213> Artificial Sequence <400> 1556 cttcatcctg ttccccatcc acgcgtctag tcactttctt ttctagttct tgctcctgta 60 aacgcattcc ctcagcgcgg tctatctctt attgctgtac tgcctccata aggtctaaac 120 cgttgtttgc atttacagcg agaatagagg ttcgttggtt gcgtataggg tac 173 <210> 1557 <211> 173 <212> DNA <213> Artificial Sequence <400> 1557 gagtagtgat ggaaaagaga ggttcacact ccaataccca aatgataatt tagtattgaa 60 ttatgatttc tcgaaagacc ccactattaa tggttggaca ggaaatggtg cgactataga 120 atattcacac gggaacatgc gagtgtggtt taacgactca gcaactaacc gaa 173 <210> 1558 <211> 173 <212> DNA <213> Artificial Sequence <400> 1558 gtccaataga tgggaaacgc ctgagaacct tgataaagag gataacgttc tattacttcg 60 tgaacgtaat aacctcatta gagaaaacga aatgctaagg gaaaagttgt tagacgctcg 120 tttagaggta gacgagttag cagatgaggt tgaccataaa agtcaacgca tag 173 <210> 1559 <211> 173 <212> DNA <213> Artificial Sequence <400> 1559 ttgggaaaat tttcaaacgc acgtacattt tggctttgtg tacaattccc gtttccttta 60 cagcctcctt ttctttcagt tcaaattttg actcaatata ttcctcatgg tcaaaaataa 120 aatacatctt atgcatatct gtcaaaacat atagttgacc gtctccgttg aac 173 <210> 1560 <211> 173 <212> DNA <213> Artificial Sequence <400> 1560 ctatacgact acgtggacga gttaaacgat ttcatacaaa cattattgga ggactactag 60 aatgaataaa ccaagtttag gactatatgt tattattgct ttgttgtttg gaggcattgg 120 cttacaccgt atgtatgagg gaaaacttgg ctcaggtttc ttgttcctat tct 173 <210> 1561 <211> 173 <212> DNA <213> Artificial Sequence <400> 1561 ccctctctta tttcatatag tgttattata ccatttatgt gtaaaacgtt gttatactag 60 ctcatacgca acatcaaggt tacctaaatc atttttagca atcttaacaa taacaaactc 120 atcctcacct tcatcctgtt ccccatccac gcgtatagtc actttctttt cta 173 <210> 1562 <211> 173 <212> DNA <213> Artificial Sequence <400> 1562 ttatcctctt tatcaaggtt ctcaggcgtt tcccatctat tggaccttag gttcactctc 60 cttataagtg aaatcacttg cgaaaaatga agcgtaacgt ttatcattaa tgtctgtagg 120 gaatacccaa gttaaatcac tagcctcaat gtaaatgcta tctgtttcta agt 173 <210> 1563 <211> 173 <212> DNA <213> Artificial Sequence <400> 1563 ctatacgact acgtggacga gttaaacgat ttcatacaaa cattaatgga ggactactag 60 aatgaataaa ccaagtttag gactatatgt tattattgct ttgttgtttg gaggcattgg 120 cttacacagt atgtatgagg gaaaacttgg ctcaggtttc ttgttcctat tct 173 <210> 1564 <211> 173 <212> DNA <213> Artificial Sequence <400> 1564 ctatacgact acgtggacga gttaaacgat ttcatacaaa cattattgga ggactactag 60 aatgaataaa ccaagtttag gactatatgt tattattgct ttgttgtttg gaggcattgg 120 cttacacagt atgtatgagg gaaaacttgg ctcaggtttc ttgttcctat tct 173 <210> 1565 <211> 173 <212> DNA <213> Artificial Sequence <400> 1565 ttgggaaaat tttcaaacgc acgtacattt tggctttgtg tacaagtccc gtttccttta 60 cagcctcctt ttctttcagt tcaaattttg actcaatata ttcctcatgg tcaaaaataa 120 aatacatctt atgcatatct gtcaaaacat atagttgacc gtctccgttg aac 173 <210> 1566 <211> 172 <212> DNA <213> Artificial Sequence <400> 1566 aaataccttg tacgtctaaa ttgtttgtct caataaacgc caaaacccaa tttaacatat 60 cctcccaatc acactgaccg tcaggacggg acgaaatttc acaatacccc tgtttggaat 120 attgtctata gggtgttcta tcgttagcct ctttctgaac aataccacca cc 172 <210> 1567 <211> 172 <212> DNA <213> Artificial Sequence <400> 1567 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgattgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ct 172 <210> 1568 <211> 172 <212> DNA <213> Artificial Sequence <400> 1568 tccccctgtc atggggtcat aactcatggc gttaccttct aatgatttcc aaagttcaaa 60 catggtacgc gcgttctctt tttgttgctt agttggtgtg aaaatagtgt tcattaattt 120 catccccctc gttcactagt atataataaa accctcgctt atgcaagggt ta 172 <210> 1569 <211> 172 <212> DNA <213> Artificial Sequence <400> 1569 ggtttccaat tcattaagta agaaacagcc tccctacctg tgcgtgtctc acggagtttc 60 aggcgtctca ttgggttacc ttttttagat tgtgtttcaa tgttctctgt aacaacaacc 120 tcttttagtc cccctgtcat ggggtcataa ctcatggcgt taccttctaa tg 172 <210> 1570 <211> 172 <212> DNA <213> Artificial Sequence <400> 1570 agtgtgttac taataaagca cactagagta tgtactaaac ctgacaaatg gctcactaat 60 gtcattaaat agccaaaacc aactgcaccc aacttaatta tggtaaacaa agcaacaata 120 taacccaccg ctaataacaa attcttaaag tagcccattt cgttctcccc cc 172 <210> 1571 <211> 172 <212> DNA <213> Artificial Sequence <400> 1571 cgttttgcgc tgtagatgat gaattccccg tactgtgtac gtgaatttgt ccatacggtc 60 ttacccctac ttgtggtaaa cctgagcgca tttgtttttc aattttcatt gaatcattct 120 cctttctctc tctaatcatt ataacacaaa aaaggaggct taagcctcct ta 172 <210> 1572 <211> 172 <212> DNA <213> Artificial Sequence <400> 1572 tgtacgtgtc cataggtatt tacctttttc tagagttggg atggttgtac tccatcctga 60 tgtaggttca tcaacgcttg aggtcttgat tgcccactct gttttagttg atttgacaga 120 ggcgccattt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tg 172 <210> 1573 <211> 172 <212> DNA <213> Artificial Sequence <400> 1573 atagggttgt cactaatgtt ttctaaatgg ttgtttcaac caaataaggg aggaaaatag 60 acatgaattt agatactaca aaattaggtg atttagtggt tgaaaaggcg cgtgagttaa 120 atgagaacac gggtattgag tctgctgagt tacttgtctt cagtgcttta gt 172 <210> 1574 <211> 172 <212> DNA <213> Artificial Sequence <400> 1574 taaggaggct taagcctcct tttttgtgtt ataatgatta gagatagaaa ggagaatgat 60 tcaatgaaaa ttgaaaaaca aatgcgctca ggtttaccac aagtaggggt aagaccgtat 120 ggacaaagtc acgtacacag tacggggaat tcatcatcta cagcgcaaaa cg 172 <210> 1575 <211> 172 <212> DNA <213> Artificial Sequence <400> 1575 tagtgaatat atgaaaattc acagcggtta tgatacgtat aatactggtt cctatagaca 60 tttgtcagtt cgccaaaata cagagttcgc cactaaatac ttgtcagagg gtggtacgag 120 tattcattta caccagagtg gtagttatta ctcatatgag aacctcaagg cg 172 <210> 1576 <211> 172 <212> DNA <213> Artificial Sequence <400> 1576 ctacgcgctc agaaatgtca tcacagaacg cgtctgtaat acgtacagcc tcctcatcat 60 gaggaatgta ggcgtgacag tctgtgttgc tctgtaacat ggtaacatgg tccctaattc 120 cctcgtagaa gtcagccata attaattgcc caatcacaca tgttagaaat tg 172 <210> 1577 <211> 172 <212> DNA <213> Artificial Sequence <400> 1577 tattgtttta cccactccca ttctgtttga aatagaaata ggtttatcac cgttgttttt 60 tacatatata ctatgcgtgt agttttgtcc tatgatgtac tgtgttcctt taatttctaa 120 cacacctctg agattattac ttgtgttctt agttacctta taattgacag ca 172 <210> 1578 <211> 172 <212> DNA <213> Artificial Sequence <400> 1578 atagggttgt cactaatgtt ttctaaatgg ttgtttcaac caaagaaggg aggaaaatag 60 acatgaattt agatactaca aaattaggtg atttagtggt tgaaaaggcg cgtgagttaa 120 atgagaaaac gggtattgag tctgctgagt tacttgtctt cagtgcttta gt 172 <210> 1579 <211> 172 <212> DNA <213> Artificial Sequence <400> 1579 gcccgtgaac ttatcgcaca aggtaaatta gatgaggcgg ataaattaat caaggaaatt 60 cgtgaggcac aagacgaaca aacagacgag gttaaccctg acgagcaacc taaggatgaa 120 caccctaagg atgatgaggc agacgaggtt gaaccagaag aaaataaaga ta 172 <210> 1580 <211> 172 <212> DNA <213> Artificial Sequence <400> 1580 tttgggtatt ggagtgtgaa cctctctttt ccatcactac tccatgcgta agctgtgtgt 60 aaaaatggat tttgaccatc ctgtacgttt gcaatactca atggctttga ctctaatgcc 120 atgttttgta cctcctctaa taatctacag aacaataata tgtatataca tt 172 <210> 1581 <211> 172 <212> DNA <213> Artificial Sequence <400> 1581 caatttctaa catgtgtgat tgggcaatta attatggctg acttatacga gggaattagg 60 gaccatgtta ccatgttaca gagcaacaca gactgtcacg cctacattcc tcatgatgag 120 gaggctgaac gtattacaga cgcgttctgt gatgacattt ctgagcgcgt ag 172 <210> 1582 <211> 172 <212> DNA <213> Artificial Sequence <400> 1582 tagtgaatat atgaaaattc acagcggtta tgatacgtat aataatggtt cctatagaca 60 tttgtcagtt cgccaaaata cagagttcgc cactaaatac ttgtcagagg gtggtacgag 120 tattcatgta caccagagtg gtagttatta ctcatatgag aacctcaagg cg 172 <210> 1583 <211> 172 <212> DNA <213> Artificial Sequence <400> 1583 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccggttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatcacta ct 172 <210> 1584 <211> 172 <212> DNA <213> Artificial Sequence <400> 1584 tgggaaaatt ttcaaacgca cgtacatttt ggctttgtgt acaattcccg tttcctttac 60 agcctccttt tctttcagtt caaattttga ctcaatatat tcctcatggt caaaaataaa 120 atacatagta tgcatatctg tcaaaacata tagttgaccg tctccgttga ac 172 <210> 1585 <211> 172 <212> DNA <213> Artificial Sequence <400> 1585 tattgtttta cccactccca ttctgtttga aatagaaata ggttgatcac cgttgttttt 60 tacatatata ctatgcgtgt agttttgtcc tatgatgtac tgtgttcctt taatttctaa 120 cacacctatg agattattac ttgtgttctt agttacctta taattgacag ca 172 <210> 1586 <211> 172 <212> DNA <213> Artificial Sequence <400> 1586 tttgggtatt ggagtgtgaa cctctctttt ccatcactac tccaagcgta agctgtgtgt 60 aaaaatggat tttgaccatc ctgtacgttt gcaatactca atggctttga ctctaatgcc 120 atgtttttta cctcctctaa taatctacag aacaataata tgtatataca tt 172 <210> 1587 <211> 172 <212> DNA <213> Artificial Sequence <400> 1587 taaggaggct taagcctcct tttttgtgtt ataatgatta gagagagaaa ggagaatgat 60 tcaatgaaaa ttgaaaaaca aatgcgctca ggtttaccac aagtaggggt aagaccgtat 120 ggacaaagtc acgtacacag tacggggaat tcatcatcta cagcgcaaaa cg 172 <210> 1588 <211> 172 <212> DNA <213> Artificial Sequence <400> 1588 tgggaaaatt ttcaaacgca cgtacatttt ggctttgtgt acaagtcccg tttcctttac 60 agcctccttt tctttcagtt caaattttga ctcaatatat tcctcatggt caaaaataaa 120 atacatagta tgcatatctg tcaaaacata tagttgaccg tctccgttga ac 172 <210> 1589 <211> 172 <212> DNA <213> Artificial Sequence <400> 1589 tttgggtatt ggagtgtgaa cctctctttt ccatcactac tccaagcgta agctgtgtgt 60 aaaaatggat tttgaccatc ctgtacgttt gcaatactca atggctttga ctctaatgcc 120 atgttttgta cctcctctaa taatctacag aacaataata tgtatataca tt 172 <210> 1590 <211> 172 <212> DNA <213> Artificial Sequence <400> 1590 tattgtttta cccactccca ttctgtttga aatagaaata ggttgatcac cgttgttttt 60 tacatatata ctatgcgtgt agttttgtcc tatgatgtac tgtgttcctt taatttctaa 120 cacacctctg agattattac ttgtgttctt agttacctta taattgacag ca 172 <210> 1591 <211> 172 <212> DNA <213> Artificial Sequence <400> 1591 cgccttgagg ttctcatatg agtaataact accactctgg tgtacatgaa tactcgtacc 60 accctctgac aagtatttag tggcgaactc tgtattttgg cgaactgaca aatgtctata 120 ggaaccagta ttatacgtat cataaccgct gtgaattttc atatattcac ta 172 <210> 1592 <211> 172 <212> DNA <213> Artificial Sequence <400> 1592 actaaagcac tgaagacaag taactcagca gactcaatac ccgtgttctc atttaactca 60 cgcgcctttt caaccactaa atcacctaat tttgtagtat ctaaattcat gtctattttc 120 ctcccttctt tggttgaaac aaccatttag aaaacattag tgacaaccct at 172 <210> 1593 <211> 172 <212> DNA <213> Artificial Sequence <400> 1593 ctacgcgctc agaaatgtca tcacagaacg cgtctgtaat acgtacagcc tcctcatcat 60 gaggaatgta ggcgtgacag tctgtgttgc tctgtaacat ggtaacatgg tccctaattc 120 cctcgtataa gtcagccata attaattgcc caatcacaca tgttagaaat tg 172 <210> 1594 <211> 171 <212> DNA <213> Artificial Sequence <400> 1594 tagggttgtc actaatgttt tctaaatggt tgtttcaacc aaataaggga ggaaaataga 60 catgaattta gatactacaa aattaggtga tttagtggtt gaaaaggcgc gtgagttaaa 120 tgagaaaacg ggtattgagt ctgctgagtt acttgtcttc agtgctttag t 171 <210> 1595 <211> 171 <212> DNA <213> Artificial Sequence <400> 1595 taggtggcgc ttgtttggct acaagtttta agctatcaaa ggacttagag caggttgata 60 acatcaacga taaaggagag agtcactaat gggaattttt atcagaaaca agccacacga 120 agagcgggca aatctatacc ccgtagcacc atcaccaatg gttgtggact t 171 <210> 1596 <211> 171 <212> DNA <213> Artificial Sequence <400> 1596 agtatcaaag tctttgctgt atgttccacg tgaaacatcc tcactgcgat agcgtacacc 60 gttgtgtaaa atataatggt ctcgctgaat ctgtttcttt tggtcatacc ttacaatgaa 120 gttaacagcg ttttctaaag ttgtacccgc agtctttact ttatcacgca t 171 <210> 1597 <211> 171 <212> DNA <213> Artificial Sequence <400> 1597 tccgtcagac actagtgttg gttgttcaga ttgcccacta ggtattatat ttgggttagg 60 ttcgtcattg aatgagaaac ggtctgttcc tgtttcgttg aaagcgtatg cggtacgtac 120 ctccccagtg gttggtaaag gtgtagtatg tgtatgcaat actttaccgt t 171 <210> 1598 <211> 171 <212> DNA <213> Artificial Sequence <400> 1598 tttgattggg tacaaatacc agacgactat ttaggaggta ataagcaatg agtaatatgt 60 ttgaggtagg tcacagagta gtatgtgtag acactttatg tgtagaagat atattggaaa 120 aaggtaatcg atataccatt gttggagtag gcagcctttt cgtgcaggtt g 171 <210> 1599 <211> 171 <212> DNA <213> Artificial Sequence <400> 1599 ttaactgtaa acggtaagga gtcaagagag tataaatacc acttgtggtt tttgcaaaaa 60 gtaccactat tgtataaaat tagtaggtat gtaaatactc gtatagcaat aaaacgcatt 120 gaaaacaggg ggggagaacg aaatgggcta ctttaagaat ttgttattag c 171 <210> 1600 <211> 171 <212> DNA <213> Artificial Sequence <400> 1600 ttacattacc tgaaaacatt catgtaacta taccagagat tagagaaatg tttttagacc 60 atgagtttga cctaaataaa aaaggtaagc ccgtagctaa aggaacgtat actgacccta 120 atactgggta tgttatggag tttggcgcgg gaggtgtcca cggagctgtt g 171 <210> 1601 <211> 171 <212> DNA <213> Artificial Sequence <400> 1601 tgcggtcacc tcattagtgg gcacttttgc gggtctaaca gacggaatca atgaatcaaa 60 agacgccatc aataagtttc aaggtgcatt aggtctttca caagagggcg cagaaaacta 120 cactcaattg gctaacgaac tagttgctga gggtttgggt agccttgagg a 171 <210> 1602 <211> 171 <212> DNA <213> Artificial Sequence <400> 1602 ctacttagac aaacgtaaag ttactgcgga actaaaccct gctttaacta aagataagca 60 acgcggacaa atggtatcta acagacgtca agggcgttta gcataaccta aggaggctta 120 agcctccatt tttgtgttat aatgattaga gatagaaagg agaatgattc a 171 <210> 1603 <211> 171 <212> DNA <213> Artificial Sequence <400> 1603 tgttttatct taatataacc taccgacact caaggtagca acaagataat ctttcaaact 60 atatacaatt ccctcattaa catagtcacg ttcaaaacgg tcatagtaga accattcatc 120 aataccaaca acctgcacga aaaggctgcc tactccaaca atggtatatc g 171 <210> 1604 <211> 171 <212> DNA <213> Artificial Sequence <400> 1604 cttaggttta aacgcctcag aagggctgta gtcccatgaa cccctgtaga ggtttggtct 60 agcagggtcg ttagacgtat ttgggtactg tgatacgtgc ccactattga cggtgaaacc 120 agttggcaat ttcgtacctc tgtagttttc atttagacca atttcgtctt t 171 <210> 1605 <211> 171 <212> DNA <213> Artificial Sequence <400> 1605 tggctaacga actagttgct gagggtttgg gtagccttga ggacatggtt gacgctatga 60 gtagggttga gcaaaacagc cctatccctg tattcggtga ggacctacag aaccttacac 120 gttacgcggt atcgttttca aagatgtttg atacagacgt aaatgaaacc c 171 <210> 1606 <211> 171 <212> DNA <213> Artificial Sequence <400> 1606 agggtgtcat acgttacagc acgtgtgaac aaacctcctg ttgatgataa gagtctggac 60 catttaggag cttcttgcgt gtcaatcata accccattct caagtttaaa acgcccatct 120 gggtcaaccc acgagaaccc acttaatgta atggggttgt ttgacccctc t 171 <210> 1607 <211> 171 <212> DNA <213> Artificial Sequence <400> 1607 taatataatg ttaataccaa cggaacaaca gcaaatggtc atagacaaat gggaaacaca 60 taatctaaat catagtgagg ttggctcagg caagacactc atggcattag aatcgtttaa 120 aaaatcatgg ctaaagaaac tcgtagtagt gtgccttgcg tctaaggtgt c 171 <210> 1608 <211> 171 <212> DNA <213> Artificial Sequence <400> 1608 tccgtcagac actagtgttg gttgttcaga ttgcccacta ggtcttatat ttgggttagg 60 ttcgtcattg aatgagaaac ggtctgttcc tgtttcgttg aaagcgtatg cggtacgtac 120 ctccccattg gttggtaaag gtgtagtatg tgtatgcaat actttaccgt t 171 <210> 1609 <211> 171 <212> DNA <213> Artificial Sequence <400> 1609 tgcctcacgg tctaagtctt tacctagttc accaagcgct ttgtagatgt cactaaagtc 60 tacataatta tcactcattt taccacctca tttaaaacgt cctctttaga aacctcctta 120 gcaatcacag tatcaaagtc tttgctgtat gttccacgtg aaacatcctc a 171 <210> 1610 <211> 171 <212> DNA <213> Artificial Sequence <400> 1610 gacaccttag acgcaaggca cactactacg agtttcttta gccctgattt tttaaacgat 60 tctaatgcca tgagtgtctt gcctgagcca acctcactat gatttagatt atgtgtttcc 120 catttgtata tgaccatttg ctgttgttcc gttggtatta acattatatt a 171 <210> 1611 <211> 171 <212> DNA <213> Artificial Sequence <400> 1611 gacgtagtac cgaagtctat ccgttcctca aatttaaagg ctcctgttcg taaacctgtt 60 gatggtgctt tgacaggcgt tgtaagggaa ggtcctgacc atgcgtttgg tgcgaatgtt 120 gtagccctct taggtttaaa cgcctcagaa gggctgtagt cccatgaacc c 171 <210> 1612 <211> 171 <212> DNA <213> Artificial Sequence <400> 1612 tcctgcaagc atgaacgggt caagtaaata ccgtcaagcg ggtaactatg cttttgataa 60 ctttaaatca caagttggct acgttattgc tctgaataaa gtacgtgacc gcgtgggcac 120 atctggaccg ggtattcatg acacatggac taattgggcg tcaggtggac a 171 <210> 1613 <211> 171 <212> DNA <213> Artificial Sequence <400> 1613 tgtccacctg acgcccaatt agtccatgtg tcatgaatac ccgttccaga tgtgcccacg 60 cggtcacgta ctttattcag agcaataacg tagccaactt gtgatttaaa gttatcaaaa 120 gcatagtgac ccgcttgacg gtatttactt gacccgttca tgcttgcagg a 171 <210> 1614 <211> 171 <212> DNA <213> Artificial Sequence <400> 1614 attctactag tagcttatag tctttcataa actcttcttt ggttttgtgc gattcaatca 60 attcaattgc cgcatatccc cacgagttcc atccgccacc tacgtcataa aagcccgcgt 120 ttgtgcgagc tgtttgaatt actcgcccgt tacctactac gtgcgagaag a 171 <210> 1615 <211> 171 <212> DNA <213> Artificial Sequence <400> 1615 agacgggtat gaggacgtac tctttgatgt acgtcagtct tatctgcgat taaacccacc 60 tactaaacaa ttacaagtgg atatacgagc gggcaaggtc cttcacttta acaaccctct 120 attgacaaga gccgtgtaca acgcatttac aaaagagtca aacgatttaa t 171 <210> 1616 <211> 171 <212> DNA <213> Artificial Sequence <400> 1616 caacaggagg tttgttcaca cgtgctgtaa cgtatgacac cctggataaa ggtaaattgg 60 cttcacttgc tgttagtgaa ttgaaaaaga aaagtcaacc tgcttttaat tatgaagtaa 120 acgtagtcaa tgtaccttct gatttaaatg taggcgatag gataaacatt g 171 <210> 1617 <211> 171 <212> DNA <213> Artificial Sequence <400> 1617 ttaactgtaa acggtaagga gtcaagagag tataaatacc actagtggtt tttgcaaaaa 60 gtaccactat tgtataaaat tagtaggtat gtaaatactc gtatagcaat aaaacgcatt 120 gaaaacatgg ggggagaacg aaatgggcta ctttaagaat ttgttattag c 171 <210> 1618 <211> 171 <212> DNA <213> Artificial Sequence <400> 1618 tatgttatgg agtttggcgc gggaggtgtc cacggagctg ttgtacagct tattcacatt 60 ggacgctttc tcatgcgtga ctacggtagt ttgtacccta atgtgtatgt gaattttgat 120 gttctttctc gtaacgtacc tgaggagaat aagcacctag tgaaagaact c 171 <210> 1619 <211> 171 <212> DNA <213> Artificial Sequence <400> 1619 tgctggcaag tagttggtta ataagtcatt gctataatag actattctgt tagttgatga 60 gtcgttaaac aacactcgca tgttcccgtt tgaatattct atagtcgcac catttcctgt 120 ccaaccagta atagtggggt ctttcgagaa atcataattc aatactaaat t 171 <210> 1620 <211> 171 <212> DNA <213> Artificial Sequence <400> 1620 tcctttgata gcttaaaact tgtagccaaa caagcgccac ctactaccat aaaacctacg 60 gttatatcta ccaaaaaggc accaatagcc ataaaaacac acgctagtat atacataatc 120 ataggtaaat atataattcg ttccatggtg aacctcctcc aattataact t 171 <210> 1621 <211> 171 <212> DNA <213> Artificial Sequence <400> 1621 tccgtcagac actagtgttg gttgttcaga ttgcccacta ggtcttatat ttgggttagg 60 ttcgtcattg aatgagaaac ggtctgttcc tgtttcgttg aaagcgtatg cggtacgtac 120 ctccccagtg gttggtaaag gtgtagtatg tgtatgcaat actttaccgt t 171 <210> 1622 <211> 171 <212> DNA <213> Artificial Sequence <400> 1622 taatataatg ttaataccaa cggaacaaca gcaaatggtc atatacaaat gggaaacaca 60 taatctaaat catagtgagg ttggctcagg caagacactc atggcattag aatcgtttaa 120 aaaatcatgg ctaaagaaac tcgtagtagt gtgccttgcg tctaaggtgt c 171 <210> 1623 <211> 171 <212> DNA <213> Artificial Sequence <400> 1623 tgtccacctg acgcccaatt agtccatgtg tcatgaatac ccggtccaga tgtgcccacg 60 cggtcacgta ctttattcag agcaataacg tagccaactt gtgatttaaa gttatcaaaa 120 gcatagtgac ccgcttgacg gtatttactt gacccgttca tgcttgcagg a 171 <210> 1624 <211> 171 <212> DNA <213> Artificial Sequence <400> 1624 tgctggctag tagttggtta ataagtcatt gctataatag actcttctgt tagttgatga 60 gtcgttaaac aacactcgca tgttcccgtt tgaatattct atagtcgcac catttcctgt 120 ccaaccagta atagtggggt ctttcgagaa atcataattc aatactaaat t 171 <210> 1625 <211> 171 <212> DNA <213> Artificial Sequence <400> 1625 atgtgtgatt gggcaattaa ttatggctga cttctacgag ggacttaggg accatgttac 60 catgttacag agcaacacag actgtcacgc ctacattcct catgatgagg aggctgaacg 120 tattacatac gcgttctgtg atgacatttc tgagcgcgta ggtattgtat t 171 <210> 1626 <211> 171 <212> DNA <213> Artificial Sequence <400> 1626 attctactag tagcttatag tctttcataa actcttcttt ggtattgtgc gattcaatca 60 attcaattgc cgcatatccc cacgagttcc atccgccacc tacgtcataa aagcccgcgt 120 ttgtgcgagc tgtttgaatt actcgcccgt tacctactac gtgcgagaag a 171 <210> 1627 <211> 171 <212> DNA <213> Artificial Sequence <400> 1627 gctaataaca aattcttaaa gtagcccatt tcgttctccc cccctgtttt caatgcgttt 60 tattgctata cgagtattta catacctact aattttatac aatagtggta ctttttgcaa 120 aaaccactag tggtatttat actctcttga ctccttaccg tttacagtta a 171 <210> 1628 <211> 170 <212> DNA <213> Artificial Sequence <400> 1628 ctgtataggc tactgatgtt gtaccatcag tgtactccca cgttgtacgt gtccataggt 60 atttaccttt ttctagagtt gggatggttg tactccatcc tgatgtaggt tcatcaacgc 120 ttgaggtctt gattgcccac tctgttttag ttgatttgac agtggcgcca 170 <210> 1629 <211> 170 <212> DNA <213> Artificial Sequence <400> 1629 cgtatcattg aatgttttcg acttacaagc gggtggagca tagagtgctg ttttaggtat 60 taccgcagac gaaaatggta ttatgacagt ggggcaggac actcaagctc cttatgtctc 120 tgttactttt gtatcagatg acgcagatgg taatgaggta tatatgggac 170 <210> 1630 <211> 170 <212> DNA <213> Artificial Sequence <400> 1630 tttagagcta ttacccatgt tagatgacgc cgtgtctagg tcttgtgcta agaaccatga 60 gttaatacca tcaacaagaa acgcatattt acttacagat tgattaactg ttttacgttc 120 ttttactgtg tatgttttac cttttacaaa gtttggcact ggttgacccg 170 <210> 1631 <211> 170 <212> DNA <213> Artificial Sequence <400> 1631 gagcgggaac gaatgccaat gaatgaggac aactttatca aactgcaatt aaccatggag 60 cgtattgacg cacgtttaga ggacgtgaga gagattaaaa aagagctgtc tggtgcccgt 120 caacaaatcg cggacctaga caaacgtctt tcgcagtcaa ttgaccatgt 170 <210> 1632 <211> 170 <212> DNA <213> Artificial Sequence <400> 1632 ttgaaagcgt atttctactc cttacccaca accacatacc aaattgaggt gttggacgtg 60 ttgtactcca tcctgaggta ggttctacag aactagttgt ttgtacatac tctgattgag 120 taccagtcac actaatacca tcctgaccaa agcgcgccac tgagtaggtt 170 <210> 1633 <211> 170 <212> DNA <213> Artificial Sequence <400> 1633 tcaaagtcac ttgcaaatag cggaatcatt agttctccat caccgtcaca gtgcaataga 60 ggtgtacggt attggtagtc aataaaaatg gtgtctgttt ccttatctac atatgcaaaa 120 caacccgcgt actcatcata tacgtccgaa tatttacctc ttaaaatagt 170 <210> 1634 <211> 170 <212> DNA <213> Artificial Sequence <400> 1634 ttggtatgtg gttgtgggta aggagtagaa atacgctttc aattggtacg tatacaaatt 60 gggtagtaac tagctcatac acgggtagag actcaatttt tattagtgct acagctccaa 120 gtaacccaac tacagggaca ttatggcaaa aacctaatga ccctactgtg 170 <210> 1635 <211> 170 <212> DNA <213> Artificial Sequence <400> 1635 tgatggagaa ctaatgattc cgctatttgc aagtgacttt gagtatgttg ttaatgagag 60 acatgagggg taaagaggag aggtcaccat gaatatttta ctagaagaaa ctgtggcatt 120 taatttggga ctgagagacg ccatctttat tagggtgtca gaacttacaa 170 <210> 1636 <211> 170 <212> DNA <213> Artificial Sequence <400> 1636 tagtgatgga aaagagaggt tcacactcca atacccaaat gataatttag tattgaatta 60 tgatttctcg aaagacccca ctattaatgg ttggacagga aatggtgcga ctatagaata 120 ttcaaactgg aacatgcgag tgttgtttaa cgactcatca actaacagaa 170 <210> 1637 <211> 170 <212> DNA <213> Artificial Sequence <400> 1637 atttatacgt tgaaggtgtg tcaccttgtt ttattgtttg ccatgtactg agagcgtcaa 60 aattacctac cctaattaac ccattattgt tgctgaatgc gtctattgtg acggaatatt 120 taactccagc tggcaagtag ttggttaata agtcattgct ataatagact 170 <210> 1638 <211> 170 <212> DNA <213> Artificial Sequence <400> 1638 cgggtcaacc agtgccaaac tttgtaaaag gtaaaacata caaagtaaaa gaacgtaaaa 60 cagttaatca atctgtaagt aaatatgcgt ttcttgttga tggtattaac tcatggttct 120 tagcacacga cctagacacg gcgtcatcta acatgggtaa tagctctaaa 170 <210> 1639 <211> 170 <212> DNA <213> Artificial Sequence <400> 1639 gagcgggaac gaatgccaat gaatgaggac aactttatca aaatgcaatt aaccatggag 60 cgtattgacg cacgtttaga ggacgtgaga gagattaaaa aagagctgtc tggtgcccgt 120 caacaaaacg cggacctaga caaacgtctt tcgcagtcaa ttgaccatgt 170 <210> 1640 <211> 170 <212> DNA <213> Artificial Sequence <400> 1640 gagcgggaac gaatgccaat gaatgaggac aactttatca aactgcaatt aaccatggag 60 cgtattgacg cacgtttaga ggacgtgaga gagattaaaa aagagctgtc tggtgcccgt 120 caacaaaacg cggacctaga caaacgtctt tcgcagtcaa ttgaccatgt 170 <210> 1641 <211> 170 <212> DNA <213> Artificial Sequence <400> 1641 cgggtcaacc agtgccaaac tttgtaaaag gtaaaacata cacagtaaaa gaacgtaaaa 60 cagttaatca atctgtaagt aaatatgcgt ttcttgttga tggtattaac tcatggttct 120 tagcacacga cctagacacg gcgtcatcta acatgggtaa tagctctaaa 170 <210> 1642 <211> 170 <212> DNA <213> Artificial Sequence <400> 1642 cgtatcattg aatgttttcg acttacaagc gggtggagca tagagtgctg ttttaggtat 60 taccgcagac gaaaatggta ttatgacagt ggggcaggac actcaagctc cttatgtctc 120 tgttactatt gtatcagatg acgcagatgg taatgaggta tatatgggac 170 <210> 1643 <211> 169 <212> DNA <213> Artificial Sequence <400> 1643 cccttgcata agcgagggtt ttattatata ctagtgaacg agggggatga aattaatgaa 60 cactattttc acaccaacta agcaacaaaa agagaacgcg cgtaccatgt ttgaactttg 120 gaaaacatta gaaggtaacg ccatgagtta tgaccccatg acaggggga 169 <210> 1644 <211> 169 <212> DNA <213> Artificial Sequence <400> 1644 gtaggtacct caggtacaac agcaccatcc acaggttggc aagcaacacc accaaatgta 60 acaggtggtc aatacctatg gacacgtatt atctggacat ttacagataa tagtaaccaa 120 acaacctcct cagtggcgcg ctttggtcag gatggtatta gtgtgactg 169 <210> 1645 <211> 169 <212> DNA <213> Artificial Sequence <400> 1645 tggtgagcct atgattttgg tcattagaat agactttcca tgtcctccgt tgcgtgtacc 60 gcgtgagaca acaatttgag catgaacagc ctcaggtttg ttctcataga cgcatgaccc 120 tatgaactca cataatgctt tttcacttag tgggtcagta aagaagttg 169 <210> 1646 <211> 169 <212> DNA <213> Artificial Sequence <400> 1646 tctgttgttg ctagactacc agtccacccc ttagagatga agacactccc tgatacagtg 60 tacgttgtac cgcgcaaagc actgtagcca tttgataggt atgcaggacg tattgttgac 120 actgctgttt tagttaattt agtggctcct gctgttggtg tagccgtta 169 <210> 1647 <211> 169 <212> DNA <213> Artificial Sequence <400> 1647 atgcaaacaa cggtttagac ctaatggagg cagtacagca atatgagaaa gtacgcgctg 60 agggaatgcg tttacaggag caagaaatag aaaagaaagt gactatacgc gtggatgggg 120 accaggatga agttgaggat gagtttgtta ttgttaagat tgctaaaaa 169 <210> 1648 <211> 169 <212> DNA <213> Artificial Sequence <400> 1648 gctgacgtat accatcaatc gttctacatg gtatagggtc tctgtgtgtc tctttctcaa 60 ttaatacttt ctctgtaggt gtcaattcgt tttcaggtag ttcgtacaag actgccccaa 120 ttggtaaagg tgtcgtctcg ttgtttacta actcatatgt tttcaaact 169 <210> 1649 <211> 169 <212> DNA <213> Artificial Sequence <400> 1649 tgaaaccatg tagggttgtt gtgttgggta gtaggttata ttttgttatt attgtacaca 60 ttcaaaaacc gtgtacactt tttgtacaaa cctgttttac gccttgtgta tcaatgtttc 120 aaccctgatt taaccattgt agtgttgtgg gatgacctca gctcttata 169 <210> 1650 <211> 169 <212> DNA <213> Artificial Sequence <400> 1650 gttgcctgac tgtaaatagc gtaagtatta caataaatga cgagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaattc cctcaggaat atcgtctaat gaaagttgtt cataattat 169 <210> 1651 <211> 169 <212> DNA <213> Artificial Sequence <400> 1651 aaaattgagt ctctacccgt gtatgagcta gttactaccc actttgtata cgtaccattt 60 gaaagcgtat ttctactcct tacccacaac cacataccaa tttgaggtgt tggacgtgtt 120 gtactccatc ctgaggtagg ttctacagaa ctagttgttt gtacatact 169 <210> 1652 <211> 169 <212> DNA <213> Artificial Sequence <400> 1652 atggaaagtc tattctaatg accaaaatca taggctcacc agtgtttgga aaaatgtaca 60 cagaactccc atctaaccgc gcatttaaca caaaaggtga gtttaatagt gcgttactag 120 ttgacaaaca gttgattttc attgatgaat tgaaccctta taatttaga 169 <210> 1653 <211> 169 <212> DNA <213> Artificial Sequence <400> 1653 ttctatcgtt gaaatatccc tctttaaatt gagggttacc tatgacaagt tcgtatacct 60 tgtccccaac tttacctaag aacgtaccta ctttattatc actatcacca cttttaaact 120 cttgcgcttg tgggtaaatg acagagtata gtagaaattc acgtacatt 169 <210> 1654 <211> 169 <212> DNA <213> Artificial Sequence <400> 1654 tgaaaccatg tagggttgtt gtgttgggta gtaggttata tattgttatt attgtacaca 60 ttcaaaaacc gtgtacactt tttgtacaaa cctgttttac gccttgtgta tcaatgtttc 120 aaccctgttt taaccattgt agtgttgtgg gatgacctca gctcttata 169 <210> 1655 <211> 169 <212> DNA <213> Artificial Sequence <400> 1655 ataatagatt agaaagggga actgacatat gaaaaatatt acctggcgcg tgaggtttag 60 caaggacaat atcttattct gggtacgatt catcattggt gtaattactc ccgctttagc 120 atacttagcg ctagaacctc aggacctaag cacatggcaa ggtttaacg 169 <210> 1656 <211> 169 <212> DNA <213> Artificial Sequence <400> 1656 cctgatgtgt ctactgagat gagagacgca ctaaacaacg accatgagaa agctgagttt 60 attagatggt gtgtacagga gtatgctgaa ctattgaaac gcagagagga cgttaccgca 120 gacgagtttg tgtggacgct atctgatgag gctaaggaaa tgcgtgagg 169 <210> 1657 <211> 169 <212> DNA <213> Artificial Sequence <400> 1657 cagtcacact aataccatcc tgaccaaagc gcgccactga gtaggttgtt tggttactct 60 tatcggtaaa tgtccagata atacgtgtcc atagggattg accacctgtt acatttggtg 120 gtgttgcgtg ccaacctgtg gttggtgcgg ttgtacctga ggtacctac 169 <210> 1658 <211> 169 <212> DNA <213> Artificial Sequence <400> 1658 tattgattgc tttattttgg gtagttatac tagcagaata ccgcacccag ttgtctgtac 60 ttgtgtttgt gattgagact tttccatctt cgcgcgtact atcatagtag gtaacacgca 120 caattaagtc tgttgttgct agactaccag tccacccctt agagatgaa 169 <210> 1659 <211> 169 <212> DNA <213> Artificial Sequence <400> 1659 ttgaaaacac agaccgtatt ttaattgatt tagaaaacga catgcgtgag caaggtgttg 60 atgaccgaac actcacatta tatgctaact atgcaatgct acaggtggca caacttctaa 120 aacttgggta tgttagtata gacgagttta ttgaaaaggc tagagagga 169 <210> 1660 <211> 169 <212> DNA <213> Artificial Sequence <400> 1660 gcaacgtcag ggtgagcaaa gcgaacttta gtcagtccca tctatacctc attaccatct 60 gcgtcatctg atacaaaagt aacagagaca taaggagctt gagtgtcctg ccccactgtc 120 ataataccat tttcgtctgc ggtaatacct aaaacagcac tatatgctc 169 <210> 1661 <211> 169 <212> DNA <213> Artificial Sequence <400> 1661 tacgtttggt tgaataatgt atcgtccgtc tgcgtctttc atcgtatcca attgagcaaa 60 tgcgctttga gaaacaaaaa ctcgttgatt gtaagcaggg tcaattgtta cgtttgacgc 120 tgttttcaat tgatcaagag aagttacttc tgttgcttcg aacttagct 169 <210> 1662 <211> 169 <212> DNA <213> Artificial Sequence <400> 1662 ttagtttgtc aagtgtatta cctagttcag cggttccgtc attacctaaa ccaaacttca 60 tatttcctac tggttttccg ctttgcacca tgtgttaatc agctcctttt ttctctagct 120 tttcaagttc ctcaggactt aagaaacgct taataaagtc agcgccatc 169 <210> 1663 <211> 169 <212> DNA <213> Artificial Sequence <400> 1663 gaacatgcga gtgttgttta acgactcatc aactaacaga atagtctatt atagcaatga 60 cttattaacc aactacttgc cagcaggagt taaatattcc gtcacaatag acgcattcag 120 caacaatcat gggttaatta gggtaggtaa ttttgacgct ctcagtaca 169 <210> 1664 <211> 169 <212> DNA <213> Artificial Sequence <400> 1664 cagcaacaac aaacaaacgc actgttacaa gcattactag acaaggacac ggacgtctac 60 ttagacaaac gtaaagttac tgcggaacta aaccctgctt taactaaaga taagcaacgc 120 ggacaaatgg tatctaacag acgtcaaggg cgtttagcat aacctaagg 169 <210> 1665 <211> 169 <212> DNA <213> Artificial Sequence <400> 1665 ccttaggtta tgctaaacgc ccttgacgtc tgttagatac cctttgtccg cgttgcttat 60 ctttagttaa agcagggttt agttccgcag taactttacg tttgtctaag tagacgtccg 120 tgtccttttc tagtaatgct tgtaacagtg cgtttgtttg ttgttgctg 169 <210> 1666 <211> 169 <212> DNA <213> Artificial Sequence <400> 1666 gcaacgtcag ggtgagcaaa gcgaacttta gtcagtccca tatatacctc attaccatct 60 gcgtcatctg atacaaaagt aacagagaca taaggagctt gagtgtcctg ccccactgtc 120 ataatacaat tttcgtctgc ggtaatacct aaaacagcac tatatgctc 169 <210> 1667 <211> 169 <212> DNA <213> Artificial Sequence <400> 1667 cctgatgtgt ctactgagat gagagacgca ctaaacaacg aacatgagaa agctgagttt 60 attagatggt gtgtacagga gtatgctgaa ctattgaaac gcagagagga cgttaccgca 120 gacgagtgtg tgtggacgct atctgatgag gctaaggaaa tgcgtgagg 169 <210> 1668 <211> 169 <212> DNA <213> Artificial Sequence <400> 1668 tacgtttggt tgaataatgt atcgtccgtc tgcgtctttc aacgtatcca attgagcaaa 60 tgcgctttga gaaacaaaaa ctcgttgatt gtaagcaggg tcaattgtta cgtttgacgc 120 tgttttctat tgatcaagag aagttacttc tgttgcttcg aacttagct 169 <210> 1669 <211> 169 <212> DNA <213> Artificial Sequence <400> 1669 taatattttt catatgtcag ttcccctttc taatctatta tctcatatat ttaaccagtg 60 atgaatgcca aaattgcacc cactacacca gtgataattg ctcctacggt tgttctagta 120 agccatgtgt tacgtgattc tagctctttg atgtcgtcct ctagtttgt 169 <210> 1670 <211> 169 <212> DNA <213> Artificial Sequence <400> 1670 ctagttacaa gtcatacggt ctgttaccta agggcgtcac gtttgaaaca accaaacgtc 60 aaacgggtca aaagattatt aaaaacaacc aatggtatta tgtaactaag aactcaggta 120 agaaaatccc tgcctcagga tgggtcagtg gatattacct acaaaacac 169 <210> 1671 <211> 169 <212> DNA <213> Artificial Sequence <400> 1671 tgtactgaga gcgtcaaaat tacctaccct aattaaccca tgattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgttc 169 <210> 1672 <211> 169 <212> DNA <213> Artificial Sequence <400> 1672 aatgtacgtg aatttctact atactctgtc atttacccac acgcgcaaga gtttaaaagt 60 ggtgatagtg ataataaagt aggtacgttc ttaggtaaag ttggggacaa ggtatacgaa 120 cttgtcatag gtaaccctca atttaaagag ggatatttca acgatagaa 169 <210> 1673 <211> 169 <212> DNA <213> Artificial Sequence <400> 1673 gagcatatag tgctgtttta ggtattaccg cagacgaaaa ttgtattatg acagtggggc 60 aggacactca agctccttat gtctctgtta cttttgtatc agatgacgca gatggtaatg 120 aggtatagat gggactgact aaagttcgct ttgctcaccc tgacgttgc 169 <210> 1674 <211> 169 <212> DNA <213> Artificial Sequence <400> 1674 ttagtttgtc aagtgtatta cctagttcag cggttccgtc attacctaaa ccaaacttca 60 tatttcctac tggttttccg ctttgcacca tgtgttaatc agctcctttt ttctctagct 120 tttcaaggtc ctcaggactt aagaaacgct taataaagtc agcgccatc 169 <210> 1675 <211> 169 <212> DNA <213> Artificial Sequence <400> 1675 gtaggtacct caggtacaac agcaccatcc acaggttggc acgcaacacc accaaatgta 60 acaggtggtc aatacctatg gacacgtatt atctggacat ttacagataa tagtaaccaa 120 acaacctcct cagtggcgcg ctttggtcag gatggtatta gtgtgactg 169 <210> 1676 <211> 169 <212> DNA <213> Artificial Sequence <400> 1676 ccttaggtta tgctaaacgc ccttgacgtc tgttagatac cctttgtccg cgttgcttat 60 ctttagttaa agcagggttt agttccgcag taactttacg tttgtctaag tagacgtccg 120 tgtccttgtc tagtaatgct tgtaacagtg cgtttgtttg ttgttgctg 169 <210> 1677 <211> 169 <212> DNA <213> Artificial Sequence <400> 1677 cctcacgcat ttccttagcc tcatcagata gcgtccacac acactcgtct gcggtaacgt 60 cctctctgcg tttcaatagt tcagcatact cctgtacaca ccatctaata aactcagctt 120 tctcatggtc gttgtttagt gcgtctctca tctcagtaga cacatcagg 169 <210> 1678 <211> 169 <212> DNA <213> Artificial Sequence <400> 1678 tgaaaccatg tagggttgtt gtgttgggta gtaggttata tattgttatt attgtacaca 60 ttcaaaaacc gtgtacactt tttgtacaaa cctgttttac gccttgtgta tcaatgtttc 120 aaccctgatt taaccattgt agtgttgtgg gatgacctca gctcttata 169 <210> 1679 <211> 169 <212> DNA <213> Artificial Sequence <400> 1679 gttgcctgac tgtaaatagc gtaagtatta caataaatga cgagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaagtc cctcaggaat atcgtctaat gaaagttgtt cataattat 169 <210> 1680 <211> 169 <212> DNA <213> Artificial Sequence <400> 1680 gtgttttgta ggtaatatcc actgacccat cctgaggcag ggattttctt acctgagttc 60 ttagttacat aataccattg gttgttttta ataatctttt gacccgtttg acgtttggtt 120 gtttcaatcg tgacgccctt aggtaacaga ccgtatgact tgtaactag 169 <210> 1681 <211> 169 <212> DNA <213> Artificial Sequence <400> 1681 tacgtttggt tgaataatgt atcgtccgtc tgcgtctttc atcgtatcca attgagcaaa 60 tgcgctttga gaaacaaaaa ctcgttgatt gtaagcaggg tcaattgtta cgtttgacgc 120 tgttttctat tgatcaagag aagttacttc tgttgcttcg aacttagct 169 <210> 1682 <211> 168 <212> DNA <213> Artificial Sequence <400> 1682 aatgggaaac acataatcta aatcatagtg aggttggctc aggcaagaca ctcatggcat 60 tagaatcgtt taaaaaatca gggctaaaga aactcgtagt agtgtgcctt gcgtctaagg 120 tgtctgagtg ggcttctgag gggtctaaac aaggtttagg tataatta 168 <210> 1683 <211> 168 <212> DNA <213> Artificial Sequence <400> 1683 ctttaaccat tgttttcctc cttaatattc aacactaaca ctgtagtacg gttgtattac 60 tacattcacg ggcacagagc ttagtagcat aatctgaaaa acctctcctg tttgcatacg 120 ttcaataaca aactctgggg aacccttata tgtgtaagag cgtccgtt 168 <210> 1684 <211> 168 <212> DNA <213> Artificial Sequence <400> 1684 tccccagagt ttgttattga acgtatgcaa acaggagagg attttcagat tatgctacta 60 agctctgtgc ccgtgaatgt agtaatacaa ccgtactaca ttgttagtgt tgaatattaa 120 ggaggaaaac aatggttaaa gttaatgaac taaaagtcgg agatgttt 168 <210> 1685 <211> 168 <212> DNA <213> Artificial Sequence <400> 1685 agtttcttct agtatgtctt ttagacggtc tgtcttgctg attttagcta ctttacttac 60 atatggtata aaaccattag acgcaaccct aagtgcgtta aacagcttgc tagggttatc 120 taattcaatt atgtcacctg agtctgtttc atatactcta tgtgtgcg 168 <210> 1686 <211> 168 <212> DNA <213> Artificial Sequence <400> 1686 taattaaatc atgaatttcc agctttgagt tacctaatga aacgcgcgaa tctgttagac 60 gcaaacctgt actactatac tctgcaccgt agccattgcc accagagttt gggttggaac 120 tgaatgtgtg tagatttagt gcgtcagggt ctagatataa ttgattgt 168 <210> 1687 <211> 168 <212> DNA <213> Artificial Sequence <400> 1687 cgcatatgat agtctgcctc gttttgcgct gtagatgatg aattccccgt actgtgtacg 60 tgaatttgtc catacggtct tacccctact tgtggtaaac ctgagcgcat ttgtttttca 120 attttcagtg aatcattctc ctttctatct ctaatcatta taacacaa 168 <210> 1688 <211> 168 <212> DNA <213> Artificial Sequence <400> 1688 taattaaatc atgaatttcc agctttgagt tacctaatga cacgcgcgaa tctgttagac 60 gcaaacctgt actactatac tctgcaccgt agccattgcc accagagttt gggttggaac 120 tgaatgtttg tagatttagt gcgtcagggt ctagatataa ttgattgt 168 <210> 1689 <211> 168 <212> DNA <213> Artificial Sequence <400> 1689 tcccgtcctg acggtcagtg tgattgggag gatatgttaa cttgggtttt ggcgtttatt 60 gagacaaaca atttagacgt acaaggtatt tgttatgacc ctgcacagtc tcaattaatt 120 accacaagac tagcagacgg gtatgaggac gtactctttg atgtacgt 168 <210> 1690 <211> 168 <212> DNA <213> Artificial Sequence <400> 1690 tgaatcattc tcctttctat ctctaatcat tataacacaa taaaggaggc ttaagcctcc 60 ttaggttatg ctaaacgccc ttgacgtctg ttagatacca tttgtccgcg ttgcttatct 120 ttagttaaag cagggtttag ttccgcagta actttacgtt tgtctaag 168 <210> 1691 <211> 168 <212> DNA <213> Artificial Sequence <400> 1691 cctctcctgt ttgcatacgt tcaataacaa actctgggga ccccttatat gtgtaagagc 60 gtccgttgac catgcagatg gtaatggtac gggtctcatt gctttcatta ataacaggtg 120 tcatataatc atctaccttt ttcacgtttc caaatactca ttactgtt 168 <210> 1692 <211> 168 <212> DNA <213> Artificial Sequence <400> 1692 tgtactgaga gcgtcaaaat tacctaccct aattaaccca gtattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgtt 168 <210> 1693 <211> 168 <212> DNA <213> Artificial Sequence <400> 1693 ctttaaccat tgttttcctc cttaatattc aacactaaca atgtagtacg gttgtattac 60 tacattcacg ggcacagagc ttagtagcat aatctgaaaa acctctcctg tttgcatacg 120 ttcaatacca aactctgggg aacccttata tgtgtaagag cgtccgtt 168 <210> 1694 <211> 168 <212> DNA <213> Artificial Sequence <400> 1694 tgtactgaga gcgtcaaaat tacctaccct aattaaccca gtattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgtt 168 <210> 1695 <211> 168 <212> DNA <213> Artificial Sequence <400> 1695 cgcacacata gagtatatga aacagactca ggtgacataa gtgaattaga taaccctagc 60 aagctgttta acgcacttag ggttgcgtct aatggtttta taccatatgt aagtaaagta 120 gctaaaaaca gcaagacaga ccgtctaaaa gacatactag aagaaact 168 <210> 1696 <211> 168 <212> DNA <213> Artificial Sequence <400> 1696 taattatacc taaaccttgt ttagacccct cagaagccca ctcagacacc ttagacgcaa 60 ggcacactac tacgagtttc tttagccctg attttttaaa cgattctaat gccatgagtg 120 tcttgccaga gccaacctca ctatgattta gattatgtgt ttcccatt 168 <210> 1697 <211> 168 <212> DNA <213> Artificial Sequence <400> 1697 tgtactgaga gcgtcaaaat tacctaccct aattaaccca atattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgtt 168 <210> 1698 <211> 168 <212> DNA <213> Artificial Sequence <400> 1698 tgtactgaga gcgtcaaaat tacctaccct aattaaccca atattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgtt 168 <210> 1699 <211> 168 <212> DNA <213> Artificial Sequence <400> 1699 cgcacacata gagtatatga aacagactca ggtgacataa gtgaattaga taaccctagc 60 aagctgttta acgcacttag ggttgcgtct aatggtttta taccatatgt aagtaaagta 120 gctaaaatca gcaagacaga ccgtctaaaa gacatactag aagaaact 168 <210> 1700 <211> 168 <212> DNA <213> Artificial Sequence <400> 1700 taattaaatc atgaatttcc agctttgagt tacctaatga cacgcgcgaa tctgttagac 60 gcaaacctgt actactatac tctgcaccgt agccattgcc accagagttt gggttggaac 120 tgaatgtgtg tagatttagt gcgtcagggt ctagatataa ttgattgt 168 <210> 1701 <211> 168 <212> DNA <213> Artificial Sequence <400> 1701 tcccttgttc gtcaagataa ccgtattcag atacctcttg agttgcctga ctgtaaatag 60 cgtaagtatt acaataaatg actagcatgc cagcgtctag ttttgaaatt ggtagctgtt 120 taagttgagg aacaaggtcc tcgtaaatca accacccttc cttagtaa 168 <210> 1702 <211> 168 <212> DNA <213> Artificial Sequence <400> 1702 aacggacgct cttacacata taagggttcc ccagagtttg gtattgaacg tatgcaaaca 60 ggagaggttt ttcagattat gctactaagc tctgtgcccg tgaatgtagt aatacaaccg 120 tactacagtg ttagtgttga atattaagga ggaaaacaat ggttaaag 168 <210> 1703 <211> 167 <212> DNA <213> Artificial Sequence <400> 1703 tgttagtata gacgagttta ttgaaaaggc tagagaggac ttataggagg taactgctta 60 tgaaacttgt aaatatgact aagaaaacta tacctacaga agataactta ctccattcaa 120 tatgggtacg cgaatatggt gggtttttcc taccatctaa tttaatg 167 <210> 1704 <211> 167 <212> DNA <213> Artificial Sequence <400> 1704 gttttgtagg taatatccac tgacccatcc tgaggcaggt attttcttac ctgagttctt 60 agttacataa taccattggt tgtttttaat aatcttttga cccgtttgac gtttggttgt 120 ttcaatcgtg acgcccttag gtaacagacc gtatgacttg taactag 167 <210> 1705 <211> 167 <212> DNA <213> Artificial Sequence <400> 1705 cattaaatta gatggtagga aaaacccacc atattcgcgg acccatattg aatggagtaa 60 gttatcttct gtaggtatag ttttcttagt catatttaca agtttcataa gcagttacct 120 cctataattc ctctctagcc ttttcaataa actcgtctat actaaca 167 <210> 1706 <211> 167 <212> DNA <213> Artificial Sequence <400> 1706 tttaatgtct ttagcaaact gctctttact aattccccat ttacgcaagt atggataggg 60 gtcaatatgg tcagaaccat tgtttggttg atgtgccgtt gcatatgcgt gagaaatgac 120 acctgtagtc ccttggtcta gcgtcttagg tagtcccgct tcatcac 167 <210> 1707 <211> 167 <212> DNA <213> Artificial Sequence <400> 1707 atggtacaat cgtgtacatt tgtaccaaaa atgtctcaat cccttgtccc ccaacgctta 60 aaaaaccgta caccaccctt tgttatttta ttatttttgt tatttaatta ttatcatcaa 120 aatgtacccc aacaaggtgt ccccatcaag ttaccccttg cgctgac 167 <210> 1708 <211> 167 <212> DNA <213> Artificial Sequence <400> 1708 tgctagtacc ttatcaggat atgcgagaat gatatgtgat gagttaaatc ttaaattaaa 60 tattgacgtg gaactagact ttgctagttt attaaacgat acattagacg aacgcaaaaa 120 acgaatgatt gagggtacag ccaaaggcat tgagtatctt aaaccta 167 <210> 1709 <211> 167 <212> DNA <213> Artificial Sequence <400> 1709 agagtatgta caaacaacta gttctgtaga acctacctca ggatggagta caacacgtcc 60 aacacctcaa attggtatgt ggttgtgggt aaggagtaga aatacgcttt caaatggtac 120 gtatacacat tgggtagtaa ctagctcata cacgggtaga gactcaa 167 <210> 1710 <211> 167 <212> DNA <213> Artificial Sequence <400> 1710 tatatatggg tcaatatagt aactatactc aagaacctag cacggaccca agtaagtaca 60 cgtggatgag aacaacggga caaaatggcg cctctgtcaa atcaactaaa acagagtggg 120 caatcaagac ctcaagcgtt gatgaaccta catcaggatg gagtaca 167 <210> 1711 <211> 167 <212> DNA <213> Artificial Sequence <400> 1711 aaccatctga ggcgtcacgt actttaaata catcattacg agcacccgca aagtgtccgc 60 caaagcgcgc gtcatattca gccttaccct tttcattcac cttaatgcgt gtagccgtaa 120 tttgttgttt aaatacctct ggttctaaat tataagggtt caattca 167 <210> 1712 <211> 167 <212> DNA <213> Artificial Sequence <400> 1712 ctctcattgg gatatattgt tttacccact cccattctga ttgaaataga aataggttta 60 tcaccgttgt tttttacata tatactatgc gtgtagtttt gtcctatgat gtactgtgtt 120 cctttaattt ctaacacacc tatgagatta ttacttgtgt tcttagt 167 <210> 1713 <211> 167 <212> DNA <213> Artificial Sequence <400> 1713 gttttcatca ttagtagcct ccttattttg attgtttgtt tcacgtgaaa cattaatacg 60 tgagcctgtc attctagaaa actgactctc gtctgtttca ggataaccat agtaggcgcg 120 tacctcggta ggtttaagat actcaatgcc tttggctgta ccctcaa 167 <210> 1714 <211> 167 <212> DNA <213> Artificial Sequence <400> 1714 gtcagcgcaa ggggtaactt gatggggaca ccttgttggt gtacattttg atgataataa 60 ttaaataaca aaaataataa aataacaaag ggtggtgtac ggttttttaa gcgttggggg 120 acaagggttt gagacatttt tggtacaaat gtacacgatt gtaccat 167 <210> 1715 <211> 167 <212> DNA <213> Artificial Sequence <400> 1715 tgtactgaga gcgtcaatat tacctaccct aaataaccct tttttgttgc tgaatgcgaa 60 ttttgtgacg gaatttttaa ctcctgctgg gaagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacact cgcatgt 167 <210> 1716 <211> 167 <212> DNA <213> Artificial Sequence <400> 1716 aaccatctga ggcgtcacgt actttaaata catcattact agcacccgca aagtgtccgc 60 caaagcgcgc gtcatattca gccttaccct tttcattcac cttaatgcgt gtagccgtaa 120 tttgttgatt aaatacctct ggttctaaat tataagggtt caattca 167 <210> 1717 <211> 167 <212> DNA <213> Artificial Sequence <400> 1717 tgaacgaagt aacgttacca atgtatgtgt tagtaaatgg ggtaaaattg cctattaata 60 cattgtttgg tgccacaggt gcagagtgta atgggttata tgacccacgt tttcaatttc 120 tatcatgggt gattgggcaa ttaattatgg ctgacttcta cgaggga 167 <210> 1718 <211> 167 <212> DNA <213> Artificial Sequence <400> 1718 ttgagtctct acccgtgtat gagctagtta ctacccaatt tgtatacgta ccatttgaaa 60 gcgtatttct actccttacc cacaaccaca taccaatttg aggtgttgga cgtgttgtac 120 tccatccaga ggtaggttct acagaactag ttgtttgtac atactct 167 <210> 1719 <211> 167 <212> DNA <213> Artificial Sequence <400> 1719 acaccattac cggttgagcc atctacagga atatagttca ctgtataggc tactgatgtt 60 gtaccatcag tgtactccca cgttgtacgt gtccataggt atttaccttt ttctagagtt 120 gggatgggtg tactccatcc tgatgtaggt tcatcaacgc ttgaggt 167 <210> 1720 <211> 167 <212> DNA <213> Artificial Sequence <400> 1720 actaagaaca caagtaataa tctcataggt gtgttagaac ttaaaggaac acagtacatc 60 ataggacaaa actacacgca tagtatatat gtaaaaaaca acggtgataa acctatttct 120 atttcaaaca gaatgggagt gggtaaaaca atatatccca atgagag 167 <210> 1721 <211> 167 <212> DNA <213> Artificial Sequence <400> 1721 tttaatgtct ttagcaaact gctctttact aattccccag ttacgcaagt atggataggg 60 gtcaatatgg tcagaaccat tgtttggttg atgtgccgtt gcatatgcgt gagaaatgac 120 acctgtattc ccttggtcta gcgtcttagg tagtcccgct tcatcac 167 <210> 1722 <211> 167 <212> DNA <213> Artificial Sequence <400> 1722 tgtactgaga gcgtcaaaat tacctaccct aattaaccct ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cgcatgt 167 <210> 1723 <211> 167 <212> DNA <213> Artificial Sequence <400> 1723 ttgagtctct acccgtgtat gagctagtta ctacccaatg tgtatacgta ccatttgaaa 60 gcgtatttct actccttacc cacaaccaca taccaatttg aggtgttgga cgtgttgtac 120 tccatccaga ggtaggttct acagaactag ttgtttgtac atactct 167 <210> 1724 <211> 167 <212> DNA <213> Artificial Sequence <400> 1724 ctctcattgg gatatattgt tttacccact cccattctga ttgaaataga aataggttta 60 tcaccgttgt tttttacata tatactatgc gtgtagtttt gtcctatgat gtactgtgtt 120 cctttaagtt ctaacacacc tatgagatta ttacttgtgt tcttagt 167 <210> 1725 <211> 167 <212> DNA <213> Artificial Sequence <400> 1725 tttaatgtct ttagcaaact gctctttact aattccccag ttacgcaagt atggataggg 60 gtcaatatgg tcagaaccat tgtttggttg atgtgccgtt gcatatgcgt gagaaatgac 120 acctgtagtc ccttggtcta gcgtcttagg tagtcccgct tcatcac 167 <210> 1726 <211> 167 <212> DNA <213> Artificial Sequence <400> 1726 gtcagcgcaa ggggtaactt gatggggaca ccttgttggt gtacattttg atgataataa 60 ttaaataaca aaaataataa aataacaaag ggtggtgtac ggttttttaa gcgttggggg 120 acaagggatt gagacatttt tggtacaaat gtacacgatt gtaccat 167 <210> 1727 <211> 167 <212> DNA <213> Artificial Sequence <400> 1727 aaccatctga ggcgtcacgt actttaaata catcattacg agcacccgca aagtgtccgc 60 caaagcgcgc gtcatattca gccttaccct tttcattcac cttaatgcgt gtagccgtaa 120 tttgttgatt aaatacctct ggttctaaat tataagggtt caattca 167 <210> 1728 <211> 167 <212> DNA <213> Artificial Sequence <400> 1728 tgttagtata gacgagttta ttgaaaaggc tagagaggac ttataggagg taactgctta 60 tgaaacttgt aaatatgact aagaaaacta tacctacaga agataactta ctccattcaa 120 tatgggtccg cgaatatggt gggtttttcc taccatctaa tttaatg 167 <210> 1729 <211> 166 <212> DNA <213> Artificial Sequence <400> 1729 ttaatagcaa cgctgtgttc tttgagtagc tcatttaagt cctcagtgtt tctatatccc 60 acaatcgcat tataagaccg tccacctaaa tactgtttct cttctataca gtagcgttct 120 ctaaaagatt tccacgttcc agagtataaa cctgcgattt tcaatt 166 <210> 1730 <211> 166 <212> DNA <213> Artificial Sequence <400> 1730 ttatacacaa tatctgatgg gatgagtttg ttgtcacgtt taatagcaac gctgtgttct 60 ttgagtagct catttaagtc ctcagtgttt ctatatccca caatcgcatt ataagaccgt 120 ccacctaaat actgtttctc ttctatacag tagcgttctc taaaag 166 <210> 1731 <211> 166 <212> DNA <213> Artificial Sequence <400> 1731 ggttcaaata gcaggtgcgt ttaaacccat aaaccaactt agcgcaggtc aatatgtcat 60 taaccaacct ctaccagttt gggctagacc attgaataac gtaacactca ttcatcaagg 120 ttctggactg aacaggctac tactagaagt gcgcaaggat ggtgca 166 <210> 1732 <211> 166 <212> DNA <213> Artificial Sequence <400> 1732 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatggt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tggagtgtga acctctcttt tccatc 166 <210> 1733 <211> 166 <212> DNA <213> Artificial Sequence <400> 1733 ctagagtcca tttttgagaa gtcgtttagc atactttgag taacatcagc ctgtgtcgct 60 ttgccgtctt tgaatgcttg aaaaacgtct cttgttttct gagaaaacat atccatgttg 120 tcatctatcc gtccgtcaac aatagagata ccaatttctt ttacta 166 <210> 1734 <211> 166 <212> DNA <213> Artificial Sequence <400> 1734 gtcagtacca atttcactat atgatagact attgtagtgt cctgaaaata gtttgtccat 60 ttcatagtaa atattttgcg cctctgatag tgtcttacac catacatcta cctgtatggt 120 tatctccatc attagggggt tattacttgc ataagagtcg tgagta 166 <210> 1735 <211> 166 <212> DNA <213> Artificial Sequence <400> 1735 taaagactgt acctgttacc aattatggaa cgtggaaaag ttacccaatc tttgaaatca 60 ccaacgcaga agaaaacggt atgattgctg ttatgaacga aaacggtaaa gtcctacagt 120 ttggcaagga agaaaacaaa gacgctacag agccaattaa agacga 166 <210> 1736 <211> 166 <212> DNA <213> Artificial Sequence <400> 1736 gtctaaaacg ttcaatctcc ttaactgaga aagctattga ggcacaaaag cgcgctattg 60 aaatgagttc tcaggagttc ggtgaaaact ctaaagaagt tgaggaggct agaatctccc 120 tatctaactt agagtcacag gctaaattat caagtaaagc tcttaa 166 <210> 1737 <211> 166 <212> DNA <213> Artificial Sequence <400> 1737 ttagagtcac aggctaaatt atcaagtaaa gctcttaact caatggagaa cgctagtgat 60 ggacttagtg acatcaaagg tggagcagac gaggctacag atggggtagg tggactatta 120 gatggtgtaa tgtctctaaa aggtggcgcg gtaatcggtg cggtca 166 <210> 1738 <211> 166 <212> DNA <213> Artificial Sequence <400> 1738 cagagtttgt tattgaacgt atgcaaacag gagaggtttt tcagattatg ctactaagct 60 ctgtgcccgt gaatgtagta atacaaccgt actacattgt tagtgttgaa tattaaggag 120 gaaaacactg gttaaagtta atgaactaaa agtcggagat gtttta 166 <210> 1739 <211> 166 <212> DNA <213> Artificial Sequence <400> 1739 agaacatgta atttgtaaat gtgcagatgg tggctcatat agttttaagt gtccagagcg 60 tttgtttgat tatgcaaaaa cctatatgaa agagtatcat aatgtagagt tgcattatga 120 tactaagtca gaagatattt ttgttataag aaatgatatg ttccta 166 <210> 1740 <211> 166 <212> DNA <213> Artificial Sequence <400> 1740 gtcagtacca atttcactat atgatagact attgtagttt cctgaaaata gtttgtccat 60 ttcatagtaa atattttgcg cctctgatag tgtcttacac catacatcta cctgtatggt 120 tatctccctc attagggggt tattacttgc ataagagtcg tgagta 166 <210> 1741 <211> 166 <212> DNA <213> Artificial Sequence <400> 1741 tgaacaggct actactagaa gtgcgcaagg atggtgcact tctagtaagt aggtatggta 60 ctacagtaga tagtgcgatt ccgtcaggcg catggataaa catctcttgc gtatatgcgg 120 gtcaagattt attctaaggg ggataattat gttagagcaa tttaaa 166 <210> 1742 <211> 166 <212> DNA <213> Artificial Sequence <400> 1742 taagtccatc actagcgttc tccattgatt taagagcttt acttgataat ttagcctgtg 60 actctaattt agatagggag attctagcct cctcaacttc tttagagttt tcaccgaact 120 cctgagacct catttcaata gcgcgctttt gtgcctcaat agcttt 166 <210> 1743 <211> 166 <212> DNA <213> Artificial Sequence <400> 1743 gtttgaaaca accaaacgtc aaacgggtca aaagattaat aaaaacaacc aatggtatta 60 tgtaactaag aactcaggta agaaaatacc tgcctcagga tgggtcagtg gatattacct 120 acaaaacact aaacgtgtgg aacacaagaa gaaagagacc tactct 166 <210> 1744 <211> 166 <212> DNA <213> Artificial Sequence <400> 1744 tcttctcgca cgtagtaggt aacgggcgag taattcaatc agcacgcaca aacgcgggct 60 tttatgacgt aggtggcgga tggaactcgt ggggatatgc ggcaattgaa ttgattgaat 120 cgcacaaaac caaagaagag tttatgaaag actataagct actagt 166 <210> 1745 <211> 166 <212> DNA <213> Artificial Sequence <400> 1745 tcgtctttaa ttggctctgt agcgtctttg ttttcttcat tgccaaactg taggacttta 60 ccgttttcgt tcataacagc aatcataccg ttttcttctg cgttggtgat ttcaaagatt 120 gggtaacatt tccacgttcc ataattggta acaggtacag tcttta 166 <210> 1746 <211> 166 <212> DNA <213> Artificial Sequence <400> 1746 taagtccatc actagcgttc tccattgatt taagagctgt acttgataat ttagcctgtg 60 actctaattt agatagggag attctagcct cctcaacttc tttagagttt tcaccgaact 120 cctgagaact catttcaata gcgcgctttt gtgcctcaat agcttt 166 <210> 1747 <211> 166 <212> DNA <213> Artificial Sequence <400> 1747 tagggttatc taattcaatt atgtcacctg agtctgtttc atatactcta tgtgtgcgta 60 gtttcttaac cattgatggt gacttgactt tatacacaat atctgatggg atgagtttgt 120 tgtcacgatt aatagcaacg ctgtgttctt tgagtagctc atttaa 166 <210> 1748 <211> 166 <212> DNA <213> Artificial Sequence <400> 1748 catattaatg tctatagcca tccgtgactc tgacgcaaaa ggcaatgaag tgattgttga 60 atactggtac ggtaacaagt tactaaaatc tatccagaca gacgtaacta agtacaaatc 120 atcttggttc cgctgtacaa tgacacgtga ccaaacgggt aagaag 166 <210> 1749 <211> 166 <212> DNA <213> Artificial Sequence <400> 1749 cacaaaacaa atagctaaag tgtttggtat acctttaatt cgttttggta tggagttagt 60 aaactcacaa gacggaacac aaaactctat ttacattgct agtaccttat caggatatgc 120 gagaatgata tgtgatgagt taaatcttaa attaaatatt gacgtg 166 <210> 1750 <211> 166 <212> DNA <213> Artificial Sequence <400> 1750 ccgcttgcgt aacgttctga ccagtttatt tcctcgaact cataaaagta tgcttcactg 60 tacgcgttta taagcgcgtc aagagggtca atcttgttgc ggttaacttg tttatcaatc 120 ataattacat cgtttgactc ttttgtaaat gcgttgtaca cggctc 166 <210> 1751 <211> 166 <212> DNA <213> Artificial Sequence <400> 1751 cacgtcaata tttaatttaa gatttaactc atcacataac attctcgcat atcctgataa 60 ggtactagca atgtaaatag agttttgtgt tccgtcttgt gagtttacta actccatacc 120 aaaacgattt aaaggtatac caaacacttt agctatttgt tttgtg 166 <210> 1752 <211> 166 <212> DNA <213> Artificial Sequence <400> 1752 cagagtttgt tattgaacgt atgcaaacag gagaggttat tcagattatg ctactaagct 60 ctgtgcccgt gaatgtagta atacaaccgt actacattgt tagtgttgaa tattaaggag 120 gaaaacaatg gttaaagtta atgaactaaa agtcggagat gtttta 166 <210> 1753 <211> 166 <212> DNA <213> Artificial Sequence <400> 1753 ggcgtacaca gacgaggagt ttgacatcac agggcgtgta gtatttattg gtatagacct 60 agcacgagta aatgacttga ccgctgttac gtgggttatt cctatccctg aaaaagaatt 120 gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggt 166 <210> 1754 <211> 166 <212> DNA <213> Artificial Sequence <400> 1754 taggaacata tcatttctta taacaaaaat atcttctgtc ttagtatcat aatgcaactc 60 tacattatga tactctttca tataggtttt tgcataatca aacaaacgct ctggacactt 120 aaaactaaat gagccaccat ctgcacattt acaaattaca tgttct 166 <210> 1755 <211> 166 <212> DNA <213> Artificial Sequence <400> 1755 actagcggat aacttagcgg agtatgctcc tatttgggca caaatgggat atacagcaga 60 tgaggcattt agtacaatgc ttgcgggtct tgacggtgga gcatataacc ttgataaggt 120 gaacgacata gtaaaagaaa ttggtatctc tattgttgac ggacgg 166 <210> 1756 <211> 166 <212> DNA <213> Artificial Sequence <400> 1756 agaacatgta atttgtaaat gtgcagatgg tggctcatat agttttaagt gtccagagcg 60 tttgtttgat tatgcaaaaa cctatatgaa agagtatcat aatgtagagt tgcattatga 120 tactaagaca gaagatattt ttgttataag aaatgatatg ttccta 166 <210> 1757 <211> 166 <212> DNA <213> Artificial Sequence <400> 1757 tactcacgac tcttatgcaa gtaataaccc cctaatgagg gagataacca tacaggtaga 60 tgtatggtgt aagacactat cagaggcgca aaatatttac tatgaaatgg acaaactatt 120 ttcaggacac tacaatagtc tatcatatag tgaaattggt actgac 166 <210> 1758 <211> 166 <212> DNA <213> Artificial Sequence <400> 1758 cacaaaacaa atagctaaag tgtttggtat acctttaatt cgttttggta tggagttagt 60 aaactcacaa gacggaacac aaaactctat ttacattgct agtaccttat caggatatgc 120 gagaatgtta tgtgatgagt taaatcttaa attaaatatt gacgtg 166 <210> 1759 <211> 166 <212> DNA <213> Artificial Sequence <400> 1759 taaagactgt acctgttacc aattatggaa cgtggaaatg ttacccaatc tttgaaatca 60 ccaacgcaga agaaaacggt atgattgctg ttatgaacga aaacggtaaa gtcctacagt 120 ttggcaagga agaaaacaaa gacgctacag agccaattaa agacga 166 <210> 1760 <211> 166 <212> DNA <213> Artificial Sequence <400> 1760 taaaacatct ccgactttta gttcattaac tttaaccagt gttttcctcc ttaatattca 60 acactaacaa tgtagtacgg ttgtattact acattcacgg gcacagagct tagtagcata 120 atctgaataa cctctcctgt ttgcatacgt tcaataacaa actctg 166 <210> 1761 <211> 166 <212> DNA <213> Artificial Sequence <400> 1761 taagtccatc actagcgttc tccattgatt taagagctgt acttgataat ttagcctgtg 60 actctaattt agatagggag attctagcct cctcaacttc tttagagttt tcaccgaact 120 cctgagacct catttcaata gcgcgctttt gtgcctcaat agcttt 166 <210> 1762 <211> 166 <212> DNA <213> Artificial Sequence <400> 1762 actagtagct tatagtcttt cataaactct tctttggtat tgtgcgattc aatcaattca 60 attgccgcat atccccacga gttccatccg ccacctacgt cataaaagcc cgcgtttgtg 120 cgtgctgatt gaattactcg cccgttacct actacgtgcg agaaga 166 <210> 1763 <211> 166 <212> DNA <213> Artificial Sequence <400> 1763 agagtaggtc tctttcttct tgtgttccac acgtttaggg ttttgtaggt aatatccact 60 gacccatcct gaggcaggta ttttcttacc tgagttctta gttacataat accattggtt 120 gtttttatta atcttttgac ccgtttgacg tttggttgtt tcaaac 166 <210> 1764 <211> 165 <212> DNA <213> Artificial Sequence <400> 1764 aacttctact aataactcat agttattcat cttcgttttc ctcctcatct aacatactaa 60 gttcttcgcg taagaacttg acaacccctt ctaatagctc aattgtttcc tctttgttta 120 ggttctctcc ttccccctct attgctcccg ttgccttacc tgtgt 165 <210> 1765 <211> 165 <212> DNA <213> Artificial Sequence <400> 1765 ttcactgttg aacgtaacag cgtaaccctc aacaatcatg tcctcatttt cctcaagtgc 60 tctaatctca atgctacgcg tctccgtttt catcattagt agcctcctta ttttgattgt 120 ttgtttctcg tgaaacatta atacgtgagc ctgtcattct agaaa 165 <210> 1766 <211> 165 <212> DNA <213> Artificial Sequence <400> 1766 ctatagaacg caagacacca ttttacccat tcatgtaaaa gagacacctg tgacgctacc 60 agagattgag aaaaatagac tatggcaagc ggtcaacttc tttactgacc cactaagtga 120 aaaagcagta tgtgagttca tagggtcatg cgtctatgag aacaa 165 <210> 1767 <211> 165 <212> DNA <213> Artificial Sequence <400> 1767 cgtttgtcta agtagacgtc cgtgtccttt tctagtactg cttgtaacag tgcgtttgtt 60 tgttgttgct gtacaatcaa ttgagcaatt agctcatcat tagaaccctg accagctacc 120 acggttgttt gtgatacacc taaccgcttt tgtgcctcag ctagt 165 <210> 1768 <211> 165 <212> DNA <213> Artificial Sequence <400> 1768 caaggcgtca taggtctcat actaaaggat gaactacagg agttagaaac tatttttcac 60 ttgatagaca cgggacacat tagcacgtat aaattgccaa aattaccaga gattaaaaca 120 tatgactgat ttgaggagga tgaatagaat ggaactaaca ttaca 165 <210> 1769 <211> 165 <212> DNA <213> Artificial Sequence <400> 1769 agtcaacatc cgtctctttg acttctaacc ccatgaaccc ctcatgttct ttcagtgaaa 60 accctttgtg ttcatggtac aggtcacaac ctagaatagg agttttcttc gtgttaaaga 120 gtttataaat aagtcctcta tcatctgact taataacagc ctgtg 165 <210> 1770 <211> 165 <212> DNA <213> Artificial Sequence <400> 1770 agcactacac gttgggagga atcagcgtgt agtgcttatt agggagaaaa acaatgtata 60 ataagtatac acatattata ccatattatt ttataaaaag ggatgtaaaa agttgtttac 120 aagtgctcca ttctgtggta ttattagaat ataattagaa aagga 165 <210> 1771 <211> 165 <212> DNA <213> Artificial Sequence <400> 1771 cgtttgtcta agtagacgtc cgtgtccttt tctagtaatg cttgtaacag tgcgtttgtt 60 tgttgttgct gtacaatcaa ttgagcaatt agctcatcat tagaaccctg accagctacc 120 acggttgatt gtgatacacc taaccgcttt tgtgcctcag ctagt 165 <210> 1772 <211> 165 <212> DNA <213> Artificial Sequence <400> 1772 ttgttctcat agacgcatga ccctatgaac tcacataatg ctttttcact tagtgggtca 60 gtaaagaagt tgaccgcttg ccatagtcta tttttctcaa tctctggtag cgtcacaggt 120 gtctcttgta catgaatggg taaaatggtg tcttgcgttc tatag 165 <210> 1773 <211> 165 <212> DNA <213> Artificial Sequence <400> 1773 gacgctctta cacatataag ggttccccag agtttgttat tgaacgtatg caaacaggag 60 aggtttttca gattatgcta ctaagctctg tgcccgtgaa tgtagtaata caaccgtact 120 acattgtgag tgttgaatat taaggaggaa aacaatggtt aaagt 165 <210> 1774 <211> 165 <212> DNA <213> Artificial Sequence <400> 1774 taacataatt atccccctta gaataaatct tgacccgcat atacgcaaga gatgtttatc 60 catgcgcctg acggaatcgc actatctact gtagtaccat acctacttac tagaattgca 120 ccatcctagc gcacttctag tagtagcctg ttcattccag aacct 165 <210> 1775 <211> 165 <212> DNA <213> Artificial Sequence <400> 1775 cacaggctgt tattaagtca gatgatagag gacttatgta taaactcttt aacacgaaga 60 aaactcctat tctaggttgt gacctgtacc atgaacacaa agggttttca ctgaaagaac 120 atgagggttt catggggtta gaagtcaaag agacggatgt tgact 165 <210> 1776 <211> 165 <212> DNA <213> Artificial Sequence <400> 1776 tttgtgcctt cttgtctaat ctaatctgtg tattgactgt actactccct attttctcac 60 tagtataaaa cactaacgta tcatctaaat catatacgtc aatcatatcc tcgttatact 120 caaaatcttg taatgttagt tccattctat tcatcctcct caaat 165 <210> 1777 <211> 165 <212> DNA <213> Artificial Sequence <400> 1777 actttaacca ttgttttcct ccttaatatt caacactaac aatgtagtac ggttgtatta 60 ctacattcac gggcacagag cttagtagca taatctgaaa aacctctcct gtttgcatac 120 gttcaatcac aaactctggg gaacccttat atgtgtaaga gcgtc 165 <210> 1778 <211> 165 <212> DNA <213> Artificial Sequence <400> 1778 tgttccacaa cttaaacagc taccaatttc aaaactatac gctggcatgc tagtcattta 60 ttgtaatact tacgctattt acagtcaggc aactcaagag gtatctgaat acggttatct 120 tgacgaaaaa gggaaaccat caggcgcctt taaggttatg aatga 165 <210> 1779 <211> 165 <212> DNA <213> Artificial Sequence <400> 1779 aacaatcatg tcatcatcca cattaataat gtaacccctg ttagaaacgc tgtacatatc 60 aaaaggctcg tccatgggtt caaaccgttc atgtttcgta ttaacgtttc tcatactttg 120 taccaccatt gacagtcgta agctcagtaa ttgacttact ttgtg 165 <210> 1780 <211> 165 <212> DNA <213> Artificial Sequence <400> 1780 cgtttgtcta agtagacgtc cgtgtccttt tctagtactg cttgtaacag tgcgtttgtt 60 tgttgttgct gtacaatcaa ttgagcaatt agctcatcat tagaaccctg accagctacc 120 acggttgatt gtgatacacc taaccgcttt tgtgcctcag ctagt 165 <210> 1781 <211> 165 <212> DNA <213> Artificial Sequence <400> 1781 gtaggtagaa cggttcaaat agcaggtgcg tttaaaccca taaaccaact tagcgcaggt 60 caatatgtca ttaaccaacc tctaccagtt tgggctagac cattgaataa cgtaacactc 120 attcatctag gttctggaat gaacaggcta ctactagaag tgcgc 165 <210> 1782 <211> 165 <212> DNA <213> Artificial Sequence <400> 1782 actttaacca ttgttttcct ccttaatatt caacactcac aatgtagtac ggttgtatta 60 ctacattcac gggcacagag cttagtagca taatctgaaa aacctctcct gtttgcatac 120 gttcaatcac aaactctggg gaacccttat atgtgtaaga gcgtc 165 <210> 1783 <211> 165 <212> DNA <213> Artificial Sequence <400> 1783 ttgttctcat agacgcatga ccctatgaac tcacatactg ctttttcact tagtgggtca 60 gtaaagaagt tgaccgcttg ccatagtcta tttttctcaa tctctggtag cgtcacaggt 120 gtctcttgta catgaatggg taaaatggtg tcttgcgttc tatag 165 <210> 1784 <211> 165 <212> DNA <213> Artificial Sequence <400> 1784 tcattcataa ccttaaaggc gcctgatggt ttcccttgtt cgtcaagata accgtattca 60 gatacctctt gagttgcctg actgtaaata gcgtaagtat tacaataaat gactagcatg 120 ccagcgtata gttttgaaat tggtagctgt ttaagttgtg gaaca 165 <210> 1785 <211> 165 <212> DNA <213> Artificial Sequence <400> 1785 cacaggctgt tattaagtca gatgatagag gacttatgta taaactcttt aacacgaaga 60 aaactcctat tctaggttgt gacctgtacc atgaacacaa agggttttca ctgaaagaac 120 atgaggggtt catggggtta gaagtcaaag agacggatgt tgact 165 <210> 1786 <211> 165 <212> DNA <213> Artificial Sequence <400> 1786 acacaggtaa ggcaacggga gcaatagagg gggaaggaga gaacctaaac aaagaggaaa 60 caattgagct attagaaggg gttgtcaagt tcttacgcga agaacttagt atgttagatg 120 aggaggacaa cgaagatgaa taactatgag ttattagtag aagtt 165 <210> 1787 <211> 164 <212> DNA <213> Artificial Sequence <400> 1787 tctagtagta gcctgttcat tccagaacct tgatgaatga gtgttacgtt attcaatggt 60 ctagcccaaa ctggtagagg ttggttaatg acatattgac ctgcgctaag ttggtttatg 120 ggtttaatcg cacctgctat ttgaaccgtt ctacctactc gcgt 164 <210> 1788 <211> 164 <212> DNA <213> Artificial Sequence <400> 1788 tctagtagta gcctgttcat tccagaacct tgatgactga gtgttacgtt attcaatggt 60 ctagcccaaa ctggtagagg ttggttaatg acatattgac ctgcgctaag ttggtttatg 120 ggtttaaacg cacctgctat ttgaaccgtt ctacctactc gcgt 164 <210> 1789 <211> 164 <212> DNA <213> Artificial Sequence <400> 1789 cgtttacagg agcaagaaat agaaaagaaa gtgactctac gcgtggatgg ggaacaggat 60 gaagttgagg atgagtttgt tattgttaag attgctaaaa atgatttagg taaccttgat 120 gttgcgtatg agctagtata acaacgtttt acacataaat ggta 164 <210> 1790 <211> 164 <212> DNA <213> Artificial Sequence <400> 1790 ttggcgtatg aagtatgagg aatgtcttat ttttgccaat gatatttttg aggagtgtga 60 gtttgctgaa cacttacagg gtgttgaacg cgttatagaa gttgtgtggt tggtgctatg 120 ataaaaatgg gtttagagtg cattgtgaca ccgtgggata gtga 164 <210> 1791 <211> 164 <212> DNA <213> Artificial Sequence <400> 1791 tgctccctat catgagcaca atggctgata ctattgaaaa ctttacaaaa gacatcttac 60 caaaagtagg gcaatattta ggtgaggtgt ttggtaagtt acaaccaata ctggaaccgg 120 ttggcgagta tattaaaacc atcacggagt tattatggaa tatg 164 <210> 1792 <211> 164 <212> DNA <213> Artificial Sequence <400> 1792 attgccttaa tacgcgaacg tttaccctca ttgtacatat agtccctcat gtcctctttt 60 accattttac gcgttattct acttctatca tctgtgttgt atctgtttgc tagaagaata 120 ccgtccgaga agagtttcaa ttcaacaagg tcaccctcat tacc 164 <210> 1793 <211> 164 <212> DNA <213> Artificial Sequence <400> 1793 gtaattcttt agtaagacaa tatccctctg tttttccatc tgtacataaa tataattgtg 60 ggaaacccca cgcgctccat tcactaaaac caattacacg cacaaccgta ccatctttaa 120 agttacactc actatcccac ggtgtcacaa tgcactctaa accc 164 <210> 1794 <211> 164 <212> DNA <213> Artificial Sequence <400> 1794 ttttaccttt tacaaagttt ggcactggtt gacccggttg gtatttagtt gctttggcgc 60 gtacttttac tttactacct acagggaaat cacgtgtgtc tgtgattttt ggtttagacg 120 gttgtggttt tggtttaggt ttgttgtcag tattggaact attt 164 <210> 1795 <211> 164 <212> DNA <213> Artificial Sequence <400> 1795 aatttagtat tgaattatga tttctcgaaa gacccctcta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctattatag caatgactta ttaaccaact actt 164 <210> 1796 <211> 164 <212> DNA <213> Artificial Sequence <400> 1796 gaagagtttc aattcaacaa ggtcaccctc attaccagtg tgctcaaata gtccactatt 60 aaaggctaaa tcaataacag gtgttttact acgtactagt tcctcacgca tttccttagc 120 ctcatcagat agcgtccaca caaactcgtc tgcggtaacg tcct 164 <210> 1797 <211> 164 <212> DNA <213> Artificial Sequence <400> 1797 cgtttacagg agcaagaaat agaaaagaaa gtgactatac gcgtggatgg ggaacaggat 60 gaagttgagg atgagtttgt tattgttaag attgctaaaa atgatttagg taaccttgat 120 gttgcgtctg agctagtata acaacgtttt acacataaat ggta 164 <210> 1798 <211> 164 <212> DNA <213> Artificial Sequence <400> 1798 tccatgattt gtttaccata ctgattatag aactcgctta cctgtttgaa aatgctaccg 60 aacgcactaa aaatcgtgtc tagtatgggt tttaataatg gataaacctt ttcaaacatg 120 atggcgcaca tattccataa taactccgtg atggttttaa tata 164 <210> 1799 <211> 164 <212> DNA <213> Artificial Sequence <400> 1799 cgtttacagg agcaagaaat agaaaagaaa gtgactctac gcgtggatgg ggaacaggat 60 gaagttgagg atgagtttgt tattgttaag attgctaaaa atgatttagg taaccttgat 120 gttgcgtctg agctagtata acaacgtttt acacataaat ggta 164 <210> 1800 <211> 164 <212> DNA <213> Artificial Sequence <400> 1800 tctagtagta gcctgttcat tccagaacct tgatgactga gtgttacgtt attcaatggt 60 ctagcccaaa ctggtagagg ttggttaatg acatattgac ctgcgctaag ttggtttatg 120 ggtttaatcg cacctgctat ttgaaccgtt ctacctactc gcgt 164 <210> 1801 <211> 164 <212> DNA <213> Artificial Sequence <400> 1801 aagtagttgg ttaataagtc attgctataa tagactcttc tgttagttga tgagtcgtta 60 aacaacactc gcatgttccc gtttgaatat tctatagtcg caccatttcc tgtccaacca 120 ttaatagagg ggtctttcga gaaatcataa ttcaatacta aatt 164 <210> 1802 <211> 164 <212> DNA <213> Artificial Sequence <400> 1802 aaatagttcc aatactgaca acaaacctaa accaaaccca caaccgtcta aaccaaaaat 60 cacagacaca cgtgatttcc ctgtaggtag taaagtaaaa gtacgcgcca aagcaactaa 120 ataccaaccg ggtcaaccag tgccaaactt tgtaaaaggt aaaa 164 <210> 1803 <211> 163 <212> DNA <213> Artificial Sequence <400> 1803 ttaatgaaca ctattttcac accaactaag caacaaaaag agaacgcgcg taccatgttt 60 gaactttgga aaacattaga aggtaacgcc atgagttatg accccatgac agggggaata 120 aaagaggttg ttgttacaga gaacattgaa acacaatcta aaa 163 <210> 1804 <211> 163 <212> DNA <213> Artificial Sequence <400> 1804 agcatgccag cgtctagttt tgaaattggt agctgtttaa gttgtggaac aaggtcctcg 60 taaatcaacc acccttcctt agtaagtccc tcaggaatat cgtctaatga aagttgttca 120 taattatata actcttgttc ttcttgctcg cgctcaatac gct 163 <210> 1805 <211> 163 <212> DNA <213> Artificial Sequence <400> 1805 ggtagcacca tgtttatctt tcaaactata ttcaagtccc tcattaacat agtcacgttc 60 aaaacggtca tagtagaacc attcatcaat accatcaacc tgcacgaaaa ggctgcctac 120 tccaacaatg gtatatcgtt tacctttttc caatatatct tct 163 <210> 1806 <211> 163 <212> DNA <213> Artificial Sequence <400> 1806 gagtggcttt tttatggtat aattaataaa gaaaccagtg taaggggggt ttttaaaata 60 gaattttatt ttactgatag ggaatttaac cctataggaa ttgcgtccac agatggagca 120 ggactcatta aaatgtcaga tgaccatgag ataatcaact atg 163 <210> 1807 <211> 163 <212> DNA <213> Artificial Sequence <400> 1807 tggcgtagat atgacgcctc aaacgtatta gacacctcat ggacagcaac aggaaaaaca 60 atcacagtaa atgcaggaca atcaaatgta tatacatatt attgttctgt agattattag 120 aggaggtaaa aaacatggca ttagagtcaa agccattgag tat 163 <210> 1808 <211> 163 <212> DNA <213> Artificial Sequence <400> 1808 cactacctcc cttgtggcta ctgagtcttt atacttgagt agccatctag atgttttaac 60 aacggaagct ttgtttgcta caggtgcatt gtaggtaaat gggttttttg taactggttt 120 aattccggtg tttgattgga tatgctcaaa gttccaagtg aac 163 <210> 1809 <211> 163 <212> DNA <213> Artificial Sequence <400> 1809 atgtgatgac ctgcgtcaat ttcaaattat tactaaaaca ggttggacgt ttgacaagac 60 tgtatacgtt gatagtgatg gtaatgaaca tgacgcacag aaagtaaacc gtgtgtttgc 120 tgtgaaaacg ggtgataaag ctgttaactt attcaaagta aaa 163 <210> 1810 <211> 163 <212> DNA <213> Artificial Sequence <400> 1810 ttaatcgcat ataagactga cgtacatcaa agagtacgtc ctcatacccg tctgctagtc 60 ttgtggtaat taattgagac tgtgcagggt cataacaaag accttgtacg tctaaattgt 120 ttgtctcaat aaacgccaaa acccaattta acatatcctc cca 163 <210> 1811 <211> 163 <212> DNA <213> Artificial Sequence <400> 1811 ggtagcacca tgtttatctt tcaaactata ttcaattccc tcattaacat agtcacgttc 60 aaaacggtca tagtagaacc attcatcaat accatcaacc tgcacgaaaa ggctgcctac 120 tccaacactg gtatatcgtt tacctttttc caatatatct tct 163 <210> 1812 <211> 163 <212> DNA <213> Artificial Sequence <400> 1812 gagtggcttt tttatggtat aattaataaa gaaacaagtg taaggggggt ttttaaaata 60 gaattttatt ttactgatag ggaatttaac cctataggaa ttgcgtccac agatggagca 120 ggactcaata aaatgtcaga tgaccatgag ataatcaact atg 163 <210> 1813 <211> 163 <212> DNA <213> Artificial Sequence <400> 1813 gcgagtgttg tttaacgact catcaactaa cagaagagtc tattatagca atgacttatt 60 aaccaactac ttgccagcag gagttaaata ttccgtcaca atagacgcat tcagcaacaa 120 taatggggta attagggtag gtaattttga cgctctcagt aca 163 <210> 1814 <211> 163 <212> DNA <213> Artificial Sequence <400> 1814 atactcaatg gctttgactc taatgccatg tttttgacct cctctcatac tctacagaac 60 aataatatgt atatacattt gattgtcctg catttactgt gattgttttt catgttgctg 120 tccatgatgt gtctaatacg tttgaggcgt catatctacg cca 163 <210> 1815 <211> 163 <212> DNA <213> Artificial Sequence <400> 1815 gcgagtgttg tttaacgact catcaactaa cagaatagtc tattatagca atgacttatt 60 aaccaactac ttgccagcag gagttaaata ttccgtcaca atagacgcat tcagcaacaa 120 taatggggta attagggtag gtaattttga cgctctcagt aca 163 <210> 1816 <211> 163 <212> DNA <213> Artificial Sequence <400> 1816 agtctattat agcaatgact tattaaccaa ctactagcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaataatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa aacaaggtga cacaccttca acg 163 <210> 1817 <211> 163 <212> DNA <213> Artificial Sequence <400> 1817 agcctcaagt gcgcccgctg agtcccctgc gtcttgtagt gcttttactt gttgttgagt 60 ctcacgttcg ttctgtttca tttctttaga aagttgtgtt agtccactct tagcgtcaat 120 gtattccttg gaggtttttt ctagttgact agttaaacca ttg 163 <210> 1818 <211> 163 <212> DNA <213> Artificial Sequence <400> 1818 aagacgcagg ggactcagcg ggcgcacttg aggctcaaca ggagggtcta aaacgttcaa 60 tctccttaac tgagaaagct attgaggcac aaaagcgcgc tattgaaatg agttctcagg 120 agttcggtga aaactctaaa gaagttgagg aggctagaat ctc 163 <210> 1819 <211> 163 <212> DNA <213> Artificial Sequence <400> 1819 gaaatttcac aatacccctg tttggaatat tgtctctagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aataaacaat 120 tctttttcag ggataggaat aacccacgta acagcggtca agt 163 <210> 1820 <211> 163 <212> DNA <213> Artificial Sequence <400> 1820 ttgtcaacta gtaacgcact attaaactca cctttggtgt taaatgcgcg gttagatggg 60 agttctgtgt acatttttcc aaacaatggt gagcctatga ttttggtcat tagaatagac 120 tttccatttc ctccgttgcg tgtaccgcgt gagacaacaa ttt 163 <210> 1821 <211> 163 <212> DNA <213> Artificial Sequence <400> 1821 ggtagcacca tgtttatctt tcaaactata ttcaagtccc tcattaacat agtcacgttc 60 aaaacggtca tagtagaacc attcatcaat accatcaacc tgcacgaaaa ggctgcctac 120 tccaacactg gtatatcgtt tacctttttc caatatatct tct 163 <210> 1822 <211> 163 <212> DNA <213> Artificial Sequence <400> 1822 gagtggcttt tttatggtat aattaataaa gaaaccagtg taaggggggt ttttaaaata 60 gaattttatt ttactgatag ggaatttaac cctataggaa ttgcgtccac agatggagca 120 ggactcaata aaatgtcaga tgaccatgag ataatcaact atg 163 <210> 1823 <211> 163 <212> DNA <213> Artificial Sequence <400> 1823 gttcacttgg aactttgagc atatccaatc aaacaacgga attaaaccag ttacaaaaaa 60 cccatttacc tacaatgcac ctgtagcaaa caaagcttcc gttgttaaaa catctagatg 120 gctactccag tataaagact cagtagccac aagggaggta gtg 163 <210> 1824 <211> 163 <212> DNA <213> Artificial Sequence <400> 1824 tggcgtagat atgacgcctc aaacgtatta gacacctcat ggacagcaac aggaaaaaca 60 atcacagtaa atgcaggaca atcaaatgta tatacatatt attgttctgt agattattag 120 aggaggtcaa aaacatggca ttagagtcaa agccattgag tat 163 <210> 1825 <211> 163 <212> DNA <213> Artificial Sequence <400> 1825 cactacctcc cttgtggcta ctgagtcttt atactggagt agccatctag atgttttaac 60 aacggaagct ttgtttgcta caggtgcatt gtaggtaaat gggttttttg taactggttt 120 aattccggtg tttgattgga tatgctcaaa gttccaagtg aac 163 <210> 1826 <211> 162 <212> DNA <213> Artificial Sequence <400> 1826 aatacaatac ctacgcgctc agaaatgtca tcacagaacg cgtctgtaat acgttcagcc 60 tcctcatcat gaggaatgta ggcgtgacag tctgtgttgc tctgtaacat ggtaacatgg 120 tccctaagtc cctcgtagaa gtcagccata attaattgcc ca 162 <210> 1827 <211> 162 <212> DNA <213> Artificial Sequence <400> 1827 tccctcgtag aagtcagcca taattaatgg cccactcaca catggtagaa attgaaaacg 60 tgggtcatat aacccattaa actctgcacc tgtggcacca aacaatgtat taataggcaa 120 ttttacccca tttactaaca catacattgg taacgttact tc 162 <210> 1828 <211> 162 <212> DNA <213> Artificial Sequence <400> 1828 attttcttac ctgagttctt agttacataa taccattggt tgtttttaat aatcttttga 60 cccgtttgac gtttggttgt ttcaatcgtg acgcccttag gtaacagacc gtatgacttg 120 taactagtct tggaacctgc acgaatgtgt aggacttcct ta 162 <210> 1829 <211> 162 <212> DNA <213> Artificial Sequence <400> 1829 gttgaaggtg tgtcaccttg ttttattgtt tgccatgtac tgagagcgtc aaaattacct 60 accctaatta acccattatt gttgctgaat gcgtctattg tgacggaata tttaactcct 120 gctggcacgt agttggttaa taagtcattg ctataataga ct 162 <210> 1830 <211> 162 <212> DNA <213> Artificial Sequence <400> 1830 aaatagttcc aatactgaca acaaacctaa accaaaccca caaccgtcta aaccaaaaat 60 cacagacaca cgtgatttcc ctgtaggtag taaagtaaaa gtacgcgcca aagcaactaa 120 ataccaaacg ggtcaaccag tgccaaactt tgtaaaaggt aa 162 <210> 1831 <211> 162 <212> DNA <213> Artificial Sequence <400> 1831 aaatggtata ataacactat atgaaataag agagtgagat tttaatgagt aaagaacctg 60 aaaaattaac agttgtagca gttgaggacg aggacaaaag tttagtgatt agtgtgtgtc 120 ctgaggacta ttctaaactg tacacattaa cattgtacaa ag 162 <210> 1832 <211> 162 <212> DNA <213> Artificial Sequence <400> 1832 ttacgagaaa gaacatcaaa attcacatac acatgagggt acaaactacc gtagtcacgc 60 atgagaaagc gtccaatgtg aataagctgt tcaacagctc cgtggacacc tcccgcgcca 120 aactccataa cataaccagt attagggtca gtatacgttc ct 162 <210> 1833 <211> 162 <212> DNA <213> Artificial Sequence <400> 1833 ttacgagaaa gaacatcaaa attcacatac acattagggt acaaactacc gtagtcacgc 60 atgagaaagc gtccaatgtg aataagctgt tcaacagctc cgtggacacc tcccgcgcca 120 aactccagaa cataaccagt attagggtca gtatacgttc ct 162 <210> 1834 <211> 162 <212> DNA <213> Artificial Sequence <400> 1834 aaatggtata ataacactat atgaaataag agagggagat tttaatgagt aaagaacctg 60 aaaaattaac agttgtagca gttgaggacg aggacaaaag tttagtgatt agtgtgtgtc 120 ctgaggaata ttctaaactg tacacattaa cattgtacaa ag 162 <210> 1835 <211> 162 <212> DNA <213> Artificial Sequence <400> 1835 tgtactgaga gcgtcaaaat tacctaccct aattcaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacact cg 162 <210> 1836 <211> 162 <212> DNA <213> Artificial Sequence <400> 1836 cgagtgttgt ttaacgactc atcaactaac agaatagtct attatagcaa tgacttatta 60 accaactact tgccagcagg agttaaatat tccgtcacaa tagacgcatt cagcaacaat 120 aatgggtgaa ttagggtagg taattttgac gctctcagta ca 162 <210> 1837 <211> 162 <212> DNA <213> Artificial Sequence <400> 1837 ctttgtacaa tgttaatgtg tacagtttag aatattcctc aggacacaca ctaatcacta 60 aacttttgtc ctcgtcctca actgctacaa ctgttaattt ttcaggttct ttactcatta 120 aaatctcact ctcttatttc atatagtgtt attataccat tt 162 <210> 1838 <211> 162 <212> DNA <213> Artificial Sequence <400> 1838 aggaacgtat actgacccta atactggtta tgttctggag tttggcgcgg gaggtgtcca 60 cggagctgtt gaacagctta ttcacattgg acgctttctc atgcgtgact acggtagttt 120 gtaccctcat gtgtatgtga attttgatgt tctttctcgt aa 162 <210> 1839 <211> 161 <212> DNA <213> Artificial Sequence <400> 1839 tatattgagt caaaatttga actgaaagaa aaggaggctg taaaggaaac gggaattgta 60 cacaaagcca aaatgtacgt gcgtttgaaa attttcccaa tggatggctc taacgcgcgc 120 gtaaacgaac cactcctaca tttctttctc agtttttatg a 161 <210> 1840 <211> 161 <212> DNA <213> Artificial Sequence <400> 1840 tggtagatgt gtgccgtgct atccgtccct tcatttgttg gtacgtaata ctagaaaggg 60 gtagctcgta gaataccatt atgtgggatg tagctaagaa gtttacccct gtacttcctg 120 ccttgaagtg tactagaata atcgcgtcct catgttgttc c 161 <210> 1841 <211> 161 <212> DNA <213> Artificial Sequence <400> 1841 ttagtttgtc aagtgtatta cctagttcag cggttccgtc aatacctaaa ccaaacttca 60 tatttcctac tggttttccg ctttgcacca tgtgttaatc agctcctttt ttctctagct 120 tttcaaggtc ctcaggactt aagaaacgct taataaagtc a 161 <210> 1842 <211> 161 <212> DNA <213> Artificial Sequence <400> 1842 taccacgctt tgagttgcct gtagtcactg tcaaatcgtt caaagaatga ggtaagggac 60 tcagttattt ttgactgagt tacattcaca ttggctaaat gtgggtgcat ggttttgaac 120 atatcaaacg taagccacgt aggagcctca tagccctctc t 161 <210> 1843 <211> 161 <212> DNA <213> Artificial Sequence <400> 1843 tatgggtcaa tatactaact atactcaaga accgagcacg gacccaagta agtacacgtg 60 gatgagaaca acgggacaaa atggcgcctc tgtcaaatca actaaaacag agtgggcaat 120 caatacctca agcgttgatg aacctacatc aggatggagt a 161 <210> 1844 <211> 161 <212> DNA <213> Artificial Sequence <400> 1844 ttagtttgtc aagtgtatta cctagttcag cgggtccgtc aatacctaaa ccaaacttca 60 tatttcctac tggttttccg ctttgcacca tgtgttaatc agctcctttt ttctctagct 120 tttcaagttc ctcaggactt aagaaacgct taataaagtc a 161 <210> 1845 <211> 161 <212> DNA <213> Artificial Sequence <400> 1845 tagcaaacga aatgaaacaa gttgaggtaa cagaggacaa cataaaggaa tataaaaaac 60 tcctcgcaca ggctcgcaaa gagtttagca acatagacaa cgaacgcaag cgggttaaaa 120 aagaaatatt acgaccctat gacgagctag aggataagat a 161 <210> 1846 <211> 161 <212> DNA <213> Artificial Sequence <400> 1846 tggtagatgt gtgccgtgct atccgtccct tcagttgttg gtacgtaata ctagaaaggg 60 gtagctcgta gaataccatt atgtgggatg tagctaagaa gtttacccct gtacttcctg 120 ccttgaattg tactagaata atcgcgtcct catgttgttc c 161 <210> 1847 <211> 161 <212> DNA <213> Artificial Sequence <400> 1847 ttttagtgct tttacttgtt gttgagtctc acgttcgttc tgtttcattt ctttagaaag 60 ttgtgttagt ccactcttag cgtcaatgta ttccttggag gttttttcta gttgactagt 120 taaaccagtg tattttgctg tggcgttatt gatttgagtg c 161 <210> 1848 <211> 161 <212> DNA <213> Artificial Sequence <400> 1848 ttacgaccct atgacgagct agaggataag atacaacatc tcagaggaat actaaaagag 60 ggtgaggacg ctttggatgt tcaaataaag gcgtatagag acgctcagag gtgttctaaa 120 tgggatgagg tacaagttac ctttgaacga tttagagagg g 161 <210> 1849 <211> 161 <212> DNA <213> Artificial Sequence <400> 1849 tactccatcc tgatgtaggt tcatcaacgc ttgtggtatt gattgcccac tctgttttag 60 ttgatttgac agaggcgcca ttttgtcccg ttgttctcat ccacgtgtac ttacttgggt 120 ccgtgctagg ttcttgagta tagttactat attgacccat a 161 <210> 1850 <211> 161 <212> DNA <213> Artificial Sequence <400> 1850 ttttagtgct tttacttgtt gttgagtctc acggtcgttc tgtttcattt ctttagaaag 60 ttgtgttagt ccactcttag cgtcaatgta ttccttggag gttttttcta gttgactagt 120 taaaccattg tattttgctg tggcgttatt gatttgagtg c 161 <210> 1851 <211> 161 <212> DNA <213> Artificial Sequence <400> 1851 ttttagtgct tttacttgtt gttgagtctc acggtcgttc tgtttcattt ctttagaaag 60 ttgtgttagt ccactcttag cgtcaatgta ttccttggag gttttttcta gttgactagt 120 taaaccagtg tattttgctg tggcgttatt gatttgagtg c 161 <210> 1852 <211> 161 <212> DNA <213> Artificial Sequence <400> 1852 tatgggtcaa tatagtaact atactcaaga accgagcacg gacccaagta agtacacgtg 60 gatgagaaca acgggacaaa atggcgcctc tgtcaaatca actaaaacag agtgggcaat 120 caataccaca agcgttgatg aacctacatc aggatggagt a 161 <210> 1853 <211> 161 <212> DNA <213> Artificial Sequence <400> 1853 tggtagatgt gtgccgtgct atccgtccct tcagttgttg gtacgtaata ctagaaaggg 60 gtagctcgta gaataccatt atgtgggatg tagctaagaa gtttacccct gtacttcctg 120 ccttgaagtg tactagaata atcgcgtcct catgttgttc c 161 <210> 1854 <211> 161 <212> DNA <213> Artificial Sequence <400> 1854 tgactttatt aagcgtttct taagtcctga ggaccttgaa aagctagaga aaaaaggagc 60 tgattaacac atggtgcaaa gcggaaaacc agtaggaaat atgaagtttg gtttaggtat 120 tgacggaccc gctgaactag gtaatacact tgacaaacta a 161 <210> 1855 <211> 160 <212> DNA <213> Artificial Sequence <400> 1855 gtctacggtg aaatgttagc gggtgccatc cgatttgacg tagtagctac agacacaaag 60 gcgggcttaa tgttcaaatt aggagctatt cctaacaacg tttctacggt aacagtagca 120 aatgcgtctg agttccctag tggtggagca ggagcctaat 160 <210> 1856 <211> 160 <212> DNA <213> Artificial Sequence <400> 1856 ttttgtgtta taatgattag agatagaaag gagaatgatt caatgaaaat tgaaaaacaa 60 atgcgctcag gtttaccaca agtaggggta agaccgtatg gacaaattca cgtacacagt 120 acggggactt catcatctac agcgcaaaac gaggcagact 160 <210> 1857 <211> 160 <212> DNA <213> Artificial Sequence <400> 1857 gtacaaccat cccaactcta gaaaaaggta aagacctatg gacacgtaca acgtgggagt 60 acactgatgg tacaacatca gtagcctata cagtgaacta tattcctgta gatggctcaa 120 ccggtaatgg tgtgaaatct atcgctgtta cttacgctgt 160 <210> 1858 <211> 160 <212> DNA <213> Artificial Sequence <400> 1858 ttgtttcccg cttggtttat tgggacgcgg tggaacttca tcaaccttgc ctgcaatttc 60 aggcttacct aaattataga acccatcttt taactcaatg tctaccctca ccactgatag 120 tggctcactg tcctcccaac gtgtaaaatc aggtttccaa 160 <210> 1859 <211> 160 <212> DNA <213> Artificial Sequence <400> 1859 cagcgtaagt aacagcgata gatttcacac cagtaccggt tgagccatct acaggaatat 60 agttcactgt ataggctact gatgttgtac catcagtgta ctcccacgtt gtacgtgtcc 120 ataggtattt acctttttct agagttggga tggttgtact 160 <210> 1860 <211> 160 <212> DNA <213> Artificial Sequence <400> 1860 gtacaaccat cccaactcta gaaaaaggta aatacctatg gacacgtaca acgtgggagt 60 acactgatgg tacaacatca gtagcctata cagtgaacta tattcctgta gatggctcaa 120 ccggtaaggg tgtgaaatct atcgctgtta cttacgctgt 160 <210> 1861 <211> 160 <212> DNA <213> Artificial Sequence <400> 1861 gacatttaca gataatagta accaaacaac ctactcagtg gcgcgctttg gtcaggatgg 60 tattagtgtg actggtactc aatcagagta tgtacaaaca actagttctg tagaacctac 120 ctcaggaggg agtacaacac gtccaacacc tcaaattggt 160 <210> 1862 <211> 160 <212> DNA <213> Artificial Sequence <400> 1862 taattgtact tcctgacgct atctttaaaa acgacacaaa tgataaacta ttattcattg 60 gtgacttaga acaagctatt actttgttca aacgtactga aatgacggta cgttggcaag 120 accacaaggt ctacggtgaa atgttagcgg gtgccatccg 160 <210> 1863 <211> 160 <212> DNA <213> Artificial Sequence <400> 1863 ttatgagttg gttattttga cagacgctaa tgacatatta atgtctatag ccatccgtga 60 ctctgacgca aaaggcaatg aagtgattgt tgaatactgg tacggtaaca agttactaaa 120 atctatccag acagacgtaa ctaagtacaa atcatcttgg 160 <210> 1864 <211> 160 <212> DNA <213> Artificial Sequence <400> 1864 taacagtgtc aaccatacct tgaatgaacc cgataacatt gttgacaaag tcaccaacta 60 aaccaattac aatttttagt agtggactaa taaaattaag gaagttcatg aacgcttcca 120 tgatttgatt accatactga ttatagaact cgcttacctg 160 <210> 1865 <211> 160 <212> DNA <213> Artificial Sequence <400> 1865 ttcatcatct acagcgcaaa acgaggcaga ctctcatatg cgcagacccg tcaacagtgg 60 gttcttctcg cacgtagtag gtaacgggcg agtaattcaa acagcacgca caaacgcggg 120 cttttatgac gtaggtggcg gatggaactc gtggggatat 160 <210> 1866 <211> 160 <212> DNA <213> Artificial Sequence <400> 1866 gtaggttgtt tggttactat tatctgtaaa tgtccagata atacgtgtcc ataggtattg 60 accacctgtt acatttggtg gtgttgcttg ccaacctgtg gatggtgctg ttgtacctga 120 ggtacctcca gcgtaagtaa cagcgataga tttcacacca 160 <210> 1867 <211> 160 <212> DNA <213> Artificial Sequence <400> 1867 ttggtttatt gggacgcggt ggaacttcat cacccttgcc tgcaatttca ggcttaccta 60 aattatagaa cccatctttt aactcaatgt ctaccctcac cactgatagt ggctcaatgt 120 cctcccaacg tgtaaaatca ggtttccaat tcattaagta 160 <210> 1868 <211> 160 <212> DNA <213> Artificial Sequence <400> 1868 gacatttaca gataatagta accaaacaac ctcctcagtg gcgcgctttg gtcaggatgg 60 tattagtgtg actggtactc aatcagagta tgtacaaaca actagttctg tagaacctac 120 ctcaggaggg agtacaacac gtccaacacc tcaaattggt 160 <210> 1869 <211> 160 <212> DNA <213> Artificial Sequence <400> 1869 gtacaaccat cccaactcta gaaaaaggta aagacctatg gacacgtaca acgtgggagt 60 acactgatgg tacaacatca gtagcctata cagtgaacta tattcctgta gatggctcaa 120 ccggtaaggg tgtgaaatct atcgctgtta cttacgctgt 160 <210> 1870 <211> 159 <212> DNA <213> Artificial Sequence <400> 1870 ccaatttgag gtgttggacg tgttgtactc catcctgagg taggttctac agaactagtt 60 gtttgtacat actctgattg agtaccagtc acactaatac catcctgacc aaagcgcgcc 120 actgaggagg ttgtttggtt actattatct gtaaatgtc 159 <210> 1871 <211> 159 <212> DNA <213> Artificial Sequence <400> 1871 tgggctagac cattgaataa cgtaacactc agtcatcaag gttctggaat gaacaggcta 60 ctactagaag tgcgcaagga tggtgcaatt ctagtaagta ggtatggtac tacagtagat 120 agtgcgattc cgtcaggcgc atggataaac atctcttgc 159 <210> 1872 <211> 159 <212> DNA <213> Artificial Sequence <400> 1872 atttgttcat atacgttctc atagaggttg gtttcactgt tgaacgtaac agcgtaaccc 60 tcaacaatca tgtcctcatt ttcctcaagt gctctaatct caatgctacg cgtctccgtt 120 ttcatcagta gtagcctcct tattttgatt gtttgtttc 159 <210> 1873 <211> 159 <212> DNA <213> Artificial Sequence <400> 1873 gtcacaatgc actctaaacc cttttttatc atagcaccaa cctcacaact tctataacgc 60 gttctacacc ctgtaagtgt tcagcaatct cacacgcctc aaaaatatca ttggcaaaaa 120 taagacagtc ctcatacttc atacgccaac taatgtacg 159 <210> 1874 <211> 159 <212> DNA <213> Artificial Sequence <400> 1874 cgtacattag ttggcgtatg aagtatgagg aatgtcttat ttttgccaat gatatttttg 60 aggcgtgtga gattgctgaa cacttacagg gtgtagaacg cgttatagaa gttgtgaggt 120 tggtgctctg ataaaaaagg gtttagagtg cattgtgac 159 <210> 1875 <211> 159 <212> DNA <213> Artificial Sequence <400> 1875 agatacgaaa aacggaacgt ttgacgcgta gactgtagta gcctccgctc ctagtccact 60 gattgttgcc tcaattgcac cgcctttagt tttgtcaagg ttgtaggttg tgtagcctgt 120 accctcggta ttgggcacat gaatatgagc agatttaaa 159 <210> 1876 <211> 159 <212> DNA <213> Artificial Sequence <400> 1876 tgagtgttac gttattcaat ggtctagccc acactggtag aggttggtta atgacatatt 60 gacctgcgct aagttggttt atgggtttaa acgcacctgc tatttgaacc gttctaccta 120 ctcgcgtggc tgtaggtgtg ttagtgtatc ccataacat 159 <210> 1877 <211> 159 <212> DNA <213> Artificial Sequence <400> 1877 tgtcagggtc aatgtactca tatgacaatt cattactcgc tgtgtcttgt aagattgtaa 60 ttgtatgagg gctgacaatc tgtagcttag taacttgtgt tccgttgcgt ctaatgattg 120 caaacgcaga cccatataaa agggtataca tggtaatag 159 <210> 1878 <211> 159 <212> DNA <213> Artificial Sequence <400> 1878 tagtagtgtg ccttgcgtct aaggtgtctg agtgggcttc tgaggggtct aaacaaggtt 60 taggtataat taccctaagt gggtctccaa agctcagagg agagcttcta gaggcgtcag 120 gaacgcaata tgtatcaatc agctttcaat catcatggc 159 <210> 1879 <211> 159 <212> DNA <213> Artificial Sequence <400> 1879 gtaaaagaga cacctgtgac gctaccagag agtgagaaaa atagactatg gcaagcggtc 60 aacttcttta ctgacccact aagtgaaaaa gcattatgtg agttcatagg gtcatgcgtc 120 tatgagaaca aacctgaggc tgttcatgct caaattgtt 159 <210> 1880 <211> 159 <212> DNA <213> Artificial Sequence <400> 1880 caccacgtat cattaaacgc tatatcatca caagagacat aaagctagtc taactttgaa 60 cgaaaatcat gtgttaaaat aatataagaa agacaagaaa ggatgacaca aacatggcaa 120 aaatcggatt taaatctgct catattcatg tgcccaata 159 <210> 1881 <211> 159 <212> DNA <213> Artificial Sequence <400> 1881 gtaaaagaga cacctgtgac gctaccagag attgagaaaa atagactatg gcaagcggtc 60 aacttcttta ctgacccact aagtgaaaaa gcattatgtg agttcatagg gtcatgcgtc 120 tatgagacca aacctgaggc tgttcatgct caaattgtt 159 <210> 1882 <211> 159 <212> DNA <213> Artificial Sequence <400> 1882 tagtagcctc cttattttga ttgtttgttt ctcgtgaaac attaatacgt gagcctgtca 60 ttctagaaaa ctgactctcg tctgtttcag gataaccata gtaggcgcgt acctcgttag 120 gtttaagata ctcaatgcct ttggctgtac cctcaaaca 159 <210> 1883 <211> 159 <212> DNA <213> Artificial Sequence <400> 1883 cccataaacc aacttagcgc aggtcaatat gacattaacc aacctctacc agtttgggct 60 agaccattga ataacgtaac actcattcat caaggttctg gaatgaacag gctactacta 120 gaagtgcgca aggatggtgc aattctagta agtaggtat 159 <210> 1884 <211> 159 <212> DNA <213> Artificial Sequence <400> 1884 ccttatcaaa cgcactttta gccatgtttt tggcaccgtt ccagatgttt tttacgcctc 60 ctgtaatttt gtcaaagaag ccagtacctt ttttgtatgc aaacttagga cgtttatgac 120 ctaacacgtg tgcagtttct tctgctgtta aaacgtggg 159 <210> 1885 <211> 159 <212> DNA <213> Artificial Sequence <400> 1885 catggacttc acacacaacc cattggcggg aacacgtgag ataagttgtg aagatggtgc 60 acttgactta cttaataatg ttgtacctgc tattaaaacc acgtcacctc aatcgtttca 120 atactacagg aacattgtca tgagagacac gggctttac 159 <210> 1886 <211> 159 <212> DNA <213> Artificial Sequence <400> 1886 tacctgagga cactgcgcca aatatcctat taaacggttc acaggacaat agtatacagt 60 attggggaat ctttgacgca gtaacggcta caccaacagc aggagccact aaattaacta 120 aaacagccgt gtcaacaata cgtcctgcat acctatcaa 159 <210> 1887 <211> 159 <212> DNA <213> Artificial Sequence <400> 1887 ttgataggta tgcaggacgt attgttgaca ctgctgtttt agttaattta gtggctcctg 60 ctgttggtgt agccgttact gcgtcaaaga ttccccaata ctgtatacta ttgtcctgtg 120 aaccgttgaa taggatattt ggcgcagtgt cctcaggta 159 <210> 1888 <211> 159 <212> DNA <213> Artificial Sequence <400> 1888 tgtactgaga gcgtcaaaat tacctaccct acttaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtcgtt aaacaacac 159 <210> 1889 <211> 159 <212> DNA <213> Artificial Sequence <400> 1889 gttggttaat aagtcattgc tataatagac tcttctgtta gttgatgagt cgttaaacaa 60 cactcgcatg ttcccgtttg aatattctat agtcgcacca tttcctgtcc aaccattaat 120 agtggggact ttcgagaaat cataattcaa tactaaatt 159 <210> 1890 <211> 159 <212> DNA <213> Artificial Sequence <400> 1890 ctaaaagcat tagttgcccc tgcggttata cactcaaatt tatattgttt tattgtttgc 60 catgtactga gagcgtcaaa attacctacc cttattaacc cattattgtt gctgaatgcg 120 tctattgtga cggaatattt aattgtgacg gaatattta 159 <210> 1891 <211> 159 <212> DNA <213> Artificial Sequence <400> 1891 tgtactgaga gcgtcaaaat tacctaccct acttaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactctt ctgttagttg atgagtcgtt aaacaacac 159 <210> 1892 <211> 159 <212> DNA <213> Artificial Sequence <400> 1892 tgttccgctt gtttgcatat ctatttcagg tactagcgct tttagtggtg agcgtcctga 60 aatgccgtca attgagttca gtctaaaatg taacatgtct ttacccttga tggtttcttt 120 cttttgagtg tcagggtcaa tgtactcata tgacaattc 159 <210> 1893 <211> 159 <212> DNA <213> Artificial Sequence <400> 1893 gttcctcacg catttcctta gcctcatcag atagcgtcca cacaaactcg tctgcggtaa 60 cgtcctctct gcgtttcaat agttcagcat actcctgtac acaccatcta ataaactcag 120 ctttctcctg ttcgttgttt agtgcgtctc tcatctcag 159 <210> 1894 <211> 159 <212> DNA <213> Artificial Sequence <400> 1894 gttggttaat aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa 60 cactcgcatg ttcccgtttg aatattctat agtcgcacca tttcctgtcc aaccattaat 120 agtggggact ttcgagaaat cataattcaa tactaaatt 159 <210> 1895 <211> 159 <212> DNA <213> Artificial Sequence <400> 1895 ttgataggta tgcaggacgt attgttgaca cggctgtttt agttaattta gtggctcctg 60 ctgttggtgt agccgttact gcgtcaaaga ttccccaata ctgtatacta ttgtcctgtg 120 aaccgttgaa taggatattt ggcgcagtgt cctcaggta 159 <210> 1896 <211> 159 <212> DNA <213> Artificial Sequence <400> 1896 gtcacaatgc actctaaacc cttttttatc agagcaccaa cctcacaact tctataacgc 60 gttctacacc ctgtaagtgt tcagcaatct cacacgcctc aaaaatctca ttggcaaaaa 120 taagacagtc ctcagactac agacgccaac taatgtacg 159 <210> 1897 <211> 159 <212> DNA <213> Artificial Sequence <400> 1897 catggacttc acacacaacc cattggcggg accacgtgag ataagttgtg aagatggtgc 60 acttgactta cttaataatg ttgtacctgc tattaaaacc acgtcacctc aatcgtttca 120 atactacagg aacattgtca tgagagacac gggctttac 159 <210> 1898 <211> 159 <212> DNA <213> Artificial Sequence <400> 1898 aacaatttga gcatgaacag cctcaggttt ggtctcatag acgcatgacc ctatgaactc 60 acataatgct ttttcactta gtgggtcagt aaagaagttg accgcttgcc atagtctatt 120 tttctcactc tctggtagcg tcacaggtgt ctcttttac 159 <210> 1899 <211> 159 <212> DNA <213> Artificial Sequence <400> 1899 gccatgatga ttgaaagctg attgatacat agtgcgttcc tgacgcctct agaagctctc 60 ctctgagctt tggagaccca cttagggtaa ttatacctaa accttgttta gacccctcag 120 aagcccactc agacacctta gacgcaaggc acactacta 159 <210> 1900 <211> 158 <212> DNA <213> Artificial Sequence <400> 1900 cgttaccgca gacgagtttg tgtggacgct atctgatgag gctaaggaaa tgcgtgagga 60 cctagtacgt agtaaaacac ctgttattga tttagccttt aatagtggac tatttgagca 120 cacgggtaat gagggtgacc ttgttgaatt gaaactct 158 <210> 1901 <211> 158 <212> DNA <213> Artificial Sequence <400> 1901 ttgacccaga tgggcgtttt aaacttgaga ctggggttat gattgacacg caagaagctc 60 ctaaatggtc cagactctta tcaacaacag gaggtttgtt cacacgtgct gtaacgtatg 120 acacccttga taaaggtaaa ttggcttcac ttgctgtt 158 <210> 1902 <211> 158 <212> DNA <213> Artificial Sequence <400> 1902 aacagcaagt gaagccaatt tacctttatc cagggtgtca tacgttacag cacgtgtgaa 60 caaacctcct gttgttgata agagtctgga ccatttagga gcttcttgcg tgtcaatcat 120 aaccccattc tcaagtttaa aacgcccatc tgggtcaa 158 <210> 1903 <211> 158 <212> DNA <213> Artificial Sequence <400> 1903 gaacgcgtct gtaatacgtt cagcctcctc atcatgagga atgtaggcgt gacagtctgt 60 gttgctctgt aacatggtaa catggtccct aattccctcg tagaagtcag ccataattaa 120 ttgcccactc acacatgtta gaaattgaaa acgtgggt 158 <210> 1904 <211> 158 <212> DNA <213> Artificial Sequence <400> 1904 gctgaacact acttagctct atggtgggaa atggatagtt ttgacgaggc ggatgacgag 60 gaaaactggt ttaaatctaa ccctcttttt gaaaaacctg acgttcgcac acatatgtta 120 gaacacacac gggctaaaaa gacagaggga gaggctaa 158 <210> 1905 <211> 158 <212> DNA <213> Artificial Sequence <400> 1905 tccgtttttc gtatctgcta aaggtacagg agaaacaacc gtatcattga atgttttcga 60 cttacaagcg ggtggagcat atagtgctgt tttaggtatt accgcagacg aaaatggtat 120 tatgacagtg gggcaggaca ctcaagctcc ttatgtct 158 <210> 1906 <211> 158 <212> DNA <213> Artificial Sequence <400> 1906 tcacaggaca atagtataca gtattgggga atctttgacg cagtaacggc tacaccaaca 60 gcaggagcca ctaaattaac taaaacagca gtgtcaacaa tacgtcctgc atacctatca 120 aatggctcca gtgctttgcg cggtacaacg tacactgt 158 <210> 1907 <211> 158 <212> DNA <213> Artificial Sequence <400> 1907 tctaggttcc ataatagttt acctaatcgt tgcgcctcta gttcctgttc attatctaga 60 gcatgaccaa ttttacagag cagtgtgtgg cgcattagtt ctaattcttt acgcagtggt 120 ctattcagtg tctcactggc gtcaaacata ttagaggc 158 <210> 1908 <211> 158 <212> DNA <213> Artificial Sequence <400> 1908 tttattaaac gatacattag acgaacgcaa aaaacgaatg tttgagggta cagccaaagg 60 cattgagtat cttaaaccta acgaggtacg cgcctactat ggttatcctg aaacagacga 120 gagtcagatt tctagaatga caggctcacg tattaatg 158 <210> 1909 <211> 158 <212> DNA <213> Artificial Sequence <400> 1909 tgtaggttca tcaacgcttg aggtattgat ggcccactct gttttagttg atttgacaga 60 ggcgccattt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 120 ttgagtatag ttactatatt gacccatata tagcggat 158 <210> 1910 <211> 158 <212> DNA <213> Artificial Sequence <400> 1910 cctgtacctt tagcagatac gaaaaacgga ccgtttgacg cgtagactgt agtagcctcc 60 gctcctagtc cactgattgt tgcctcaatt gcaccgcctt tagttttgtc aaggttgtag 120 gttgtgtagc ctgtaccctc gttattgggc acatgaat 158 <210> 1911 <211> 158 <212> DNA <213> Artificial Sequence <400> 1911 aacgaacgat aagtacagat accttggtga ctgtgcgtat tttcaaaacg gtgcgctaaa 60 catgcgtaca ttagaactac gtccgtttga accatgggac tatagaacgc aagacaccat 120 tttacccatt catgtaaaag agacacctgt gacgctac 158 <210> 1912 <211> 158 <212> DNA <213> Artificial Sequence <400> 1912 gtagcgtcac aggtgtctct tttacatgaa ggggtaaaat ggtgtcttgc gttctatagt 60 cccatggttc aaacggacgt agttctaatg tacgcatgtt tagcgcaccg ttttgaaaat 120 acgcacattc accaaggtat ctgtacttat cgttcgtt 158 <210> 1913 <211> 158 <212> DNA <213> Artificial Sequence <400> 1913 tgtaggttca tcaacgcttg aggtattgat tgcccactct gttttagttg atttgacaga 60 ggcgccattt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 120 ttgagtagag ttactatatt gacccatata tagcggat 158 <210> 1914 <211> 158 <212> DNA <213> Artificial Sequence <400> 1914 agataattac ccaactgcgc catttcttta tctttaacta actgctcttg tgattcatca 60 aaatgtaata cccctgtgaa ctctataatg tcatctgttt catagttgat tatctcatgg 120 tcatctgaca ttttaatgag tcctgctcca tctgtgga 158 <210> 1915 <211> 158 <212> DNA <213> Artificial Sequence <400> 1915 tattaaccaa ctacttgcca gcaggagtta aatattccgt cacaatagac gcattcagca 60 acaataatgg gttaattagg gtaggtaatt ttgacgctct cagtacatgg caaacaataa 120 aacaaggaga cacaccttca acgtataaat ttgagggt 158 <210> 1916 <211> 158 <212> DNA <213> Artificial Sequence <400> 1916 tcttcagatg ggtttggggt gtagatggtt gccgtgtttc ctagttcgat ttttattttt 60 gttatagtta taattaaagc atttgaatta ccctgtatac taaaagcatt agttgcccct 120 gcggttagac cctcaaattt atacgttgaa ggtgtgtc 158 <210> 1917 <211> 158 <212> DNA <213> Artificial Sequence <400> 1917 tttattaaac gatacattag acgaacgcaa caaacgaatg tttgagggta cagccaaagg 60 cattgagtat cttaaaccta acgaggtacg cgcctactat ggttatcctg aaacagacga 120 gagtcagttt tctagaatga caggctcacg tattaatg 158 <210> 1918 <211> 158 <212> DNA <213> Artificial Sequence <400> 1918 tccacagatg gagcaggact cattaaaatg acagatgacc atgagataat caactatgaa 60 acagatgaca ttatagagtt cacaggggta ttacattttg atgaatcaca agagcagtta 120 gttaaagtta aagaaatggc gcagttgggt aattatct 158 <210> 1919 <211> 158 <212> DNA <213> Artificial Sequence <400> 1919 tctaggttcc ataatagttt acctaatcgt agcgcctcta gttcctgttc attatctaga 60 gcatgaccaa ttttacagag cagtgtgtgg cgcattagtt ctaattcttt acgcagtggt 120 ctattcattg tctcactggc gtcaaacata ttagaggc 158 <210> 1920 <211> 158 <212> DNA <213> Artificial Sequence <400> 1920 acagtgtacg ttgtaccgcg caaagcactg gagccatttg ataggtatgc aggacgtatt 60 gttgacactg ctgttttagt taatttagtg gctcctgctg ttggtgtagc cgttactgcg 120 tcaaagagtc cccaatactg tatactattg tcctgtga 158 <210> 1921 <211> 158 <212> DNA <213> Artificial Sequence <400> 1921 cattaatacg tgagcctgtc attctagaaa tctgactctc gtctgtttca ggataaccat 60 agtaggcgcg tacctcgtta ggtttaagat actcaatgcc tttggctgta ccctcaaaca 120 ttcgtttgtt gcgttcgtct aatgtatcgt ttaataaa 158 <210> 1922 <211> 158 <212> DNA <213> Artificial Sequence <400> 1922 tgtaggttca tcaacgcttg aggtattgat ggcccactct gttttagttg atttgacaga 60 ggcgccattt tgtcccgttg ttctcatcca cgtgtactta cttgggtccg tgctaggttc 120 ttgagtagag ttactatatt gacccatata tagcggat 158 <210> 1923 <211> 158 <212> DNA <213> Artificial Sequence <400> 1923 gaacgcgtct gtaatacgtt cagcctcctc ctcatgagga atgtaggcgt gacagtctgt 60 gttgctctgt aacatggtaa catggtccct aattccctcg tagaagtcag ccataattaa 120 ttgcccactc acacatgtta gaaattgaaa acgtgggt 158 <210> 1924 <211> 158 <212> DNA <213> Artificial Sequence <400> 1924 aacagcaagt gaagccaatt tacctttatc cagggtgtca tacgttacag cacgtgtgaa 60 caaacctcct gttgttgata agagtctgga ccatttagga gcttcttgcg tgtcaatcat 120 aaccccagtc tcaagtttaa aacgcccatc tgggtcaa 158 <210> 1925 <211> 158 <212> DNA <213> Artificial Sequence <400> 1925 tccacagatg gagcaggact cattaaaatg acagatgacc atgagataat caactatgaa 60 acagatgaca ttatagagtt cacaggggta ttacattttg atgaatcaca agagcagtta 120 gttaaagata aagaaatggc gcagttgggt aattatct 158 <210> 1926 <211> 158 <212> DNA <213> Artificial Sequence <400> 1926 gtagcgtcac aggtgtctct tttacatgaa ggggtaaaat ggtgtcttgc gttctatagt 60 cccatggttc aaacggacgt agttctaatg tacgcatgtt tagcgcaccg ttttgaaaat 120 acgcacagtc accaaggtat ctgtacttat cgttcgtt 158 <210> 1927 <211> 158 <212> DNA <213> Artificial Sequence <400> 1927 tctaggttcc ataatagttt acctaatcgt agcgcctcta gttcctgttc attatctaga 60 gcatgaccaa ttttacagag cagtgtgtgg cgcattagtt ctaattcttt acgcagtggt 120 ctattcagtg tctcactggc gtcaaacata ttagaggc 158 <210> 1928 <211> 157 <212> DNA <213> Artificial Sequence <400> 1928 taatcagcgc acaagataat agtcatttaa caaaagagga gcgtattgag cgcgagcaag 60 aagaacaaga gttatataat tatgaacaac tttcattaga cgatattcct gagggactta 120 ctaaggaagg gtggttgatt tacgaggacc ttgttcc 157 <210> 1929 <211> 157 <212> DNA <213> Artificial Sequence <400> 1929 gaatcaatga atcaaaagac gccatcaata agtttcaagg tgcattaggt ctttcacaag 60 agggcgcaga aaactacact caaatggcta acgaactagt tgctgagggt ttgggtagcc 120 ttgaggacat ggttgacgct atgagtaggg ttgagca 157 <210> 1930 <211> 157 <212> DNA <213> Artificial Sequence <400> 1930 ggtaaagagt ctaaacaaga aaaggtgatg gatggcgctg actttattaa gcgtttctta 60 agtcctgagg accttgaaaa gctagagaaa aaaggagctg attaacacat ggtgcaaagc 120 ggaaaaccag taggaaatat gaagtttggt ttaggta 157 <210> 1931 <211> 157 <212> DNA <213> Artificial Sequence <400> 1931 tactactaga agtgcgcaag gatggtgcaa ttctagtaag taggtatggt actacagtag 60 atagtgcgat tccgtcaggc gcatggataa acatctcttg cgtatatgcg ggtcaagatt 120 tattctatgg gggataatta tgttagagca atttaaa 157 <210> 1932 <211> 157 <212> DNA <213> Artificial Sequence <400> 1932 cgggctaaaa agacagaggg agaggctaaa ggtaatctca ccaacttcct aactaaggag 60 cttaattttt gggttgcgga ccaagcaacg tcatacattt ctgtagacga gtgggaaatg 120 gcgtacacag acgaggagtt tgacatcaca gggcgtg 157 <210> 1933 <211> 157 <212> DNA <213> Artificial Sequence <400> 1933 ccttgtcccc caacgcttaa aaaaccgtac accacccttt gttattttat tatttttgtt 60 atttaattat tatcatcaaa atgtacccca acaaggtgtc cccatcaagt taccccttgc 120 gctgacggaa aaagtatgct aacataataa acgaaga 157 <210> 1934 <211> 157 <212> DNA <213> Artificial Sequence <400> 1934 taatgagcgg aactccaatt tctaacggac tgttagaaca atggttttct caattgaaaa 60 tcgcaggttt atactctgga acgtggaaat cttttagaga acgctactgt atagaagaga 120 aacagtattt aggtggacgg tcttataatg cgattgt 157 <210> 1935 <211> 157 <212> DNA <213> Artificial Sequence <400> 1935 gaaatttcac aatacccctg tttggaatag tgtctatagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aataaacaat 120 tctttttcag ggataggaat aacccacgta acagcgg 157 <210> 1936 <211> 157 <212> DNA <213> Artificial Sequence <400> 1936 taatgagcgg aactccaatt tctaacggaa tgttagaaca atggttttct caattgaaaa 60 tcgcaggttt atactctgga acgtggaaat cttttagaga acgctactgt atagaagaga 120 aacagtagtt aggtggacgg tcttataatg cgattgt 157 <210> 1937 <211> 157 <212> DNA <213> Artificial Sequence <400> 1937 gatgaggtac aagttacctt tgaacgattg agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataaatg agtcccttac ctcattcttt gaacgat 157 <210> 1938 <211> 157 <212> DNA <213> Artificial Sequence <400> 1938 ggtaagaacg taacgatgtg gggacgaaat ggaacccacg ttttaacagc agaagaaact 60 gcacaagtgt taggtcataa acgtcctaag tttgcataca aaaaaggtac tggcttcttt 120 gacaaaatta caggaggcgt aaaaaacatc tggaacg 157 <210> 1939 <211> 157 <212> DNA <213> Artificial Sequence <400> 1939 agttcataaa tgaggtcgtc catggctaac gcgttgccat ggaactcctc ctctagaact 60 ctgttaaaca gcatatttaa ctcatcatca aacccattac cgtttaatac cttgttaata 120 tactccgatt taaattgctc taacataatt atccccc 157 <210> 1940 <211> 157 <212> DNA <213> Artificial Sequence <400> 1940 tttcgtcccc acatcgttac gttcttacca ttagggataa ccgcttgacc acttgggtca 60 ataaccattt cagcaccacg tccatcattg acagtcatgg gaccatctac agggtgaccg 120 ccacttggtg tacctttggc gtattcaggt gcctccc 157 <210> 1941 <211> 157 <212> DNA <213> Artificial Sequence <400> 1941 ttgcatatgc gtgagaaatg acacctgtat tcccttggtc tagcgtctta ggtagtcccg 60 cttcatcaca taatagacga attaattcta ctagtagctt atagtctttc ataaactctt 120 ctttggtatt gtgcgattca atcaattcaa ttgccgc 157 <210> 1942 <211> 157 <212> DNA <213> Artificial Sequence <400> 1942 tcgtgtactc aatgtctata ggtaggtcca ccttatcgcg acaataggtt aatggataaa 60 tgtcttttac ttctggtgtc atttctgtgt gtattgtagg aatcatcatg cctgttttct 120 cctttcggtc ttcgtttatt atgttagcat acttttt 157 <210> 1943 <211> 157 <212> DNA <213> Artificial Sequence <400> 1943 ttgcatatgc gtgagaaatg acacctgtag tcccttggtc tagcgtctta ggtagtcccg 60 cttcatcaca taatagacga attaattcta ctagtagctt atagtctttc ataaactctt 120 ctttggtatt gtgcgattca atcaattcaa ttgccgc 157 <210> 1944 <211> 157 <212> DNA <213> Artificial Sequence <400> 1944 atggttgacg ctatgagtag ggttgagcac aacagcccta tccctgtatt cggtgaggac 60 ctacagaacc ttacacgtta cgcggtatcg ttttcaaaga tgtttgatac agacgtaaat 120 gaaaccctac gcggtgcggg cgccattatg aactcgt 157 <210> 1945 <211> 157 <212> DNA <213> Artificial Sequence <400> 1945 ttagaccagt atggtacgcg tttgctaaat tcctcagcaa cctcaggcgc tatgtcgttc 60 attattttat ttgcctcacg gtctaagtct ttacctagtt caccaagcgc tttgtagatg 120 tcactaacgt ctacataatt atcactcatt ttaccac 157 <210> 1946 <211> 157 <212> DNA <213> Artificial Sequence <400> 1946 gtggtaaaat gagtgataat tatgtagacg ttagtgacat ctacaaagcg cttggtgaac 60 taggtaaaga cttagaccgt gaggcaaata aaataatgaa cgacatagcg cctgaggttg 120 ctgaggactt tagcaaacgc gtaccatact ggtctaa 157 <210> 1947 <211> 157 <212> DNA <213> Artificial Sequence <400> 1947 taatgagcgg aactccaatt tctaacggac tgttagaaca atggttttct caattgaaaa 60 tcgcaggttt atactctgga acgtggaaat cttttagaga acgctactgt atagaagaga 120 aacagtagtt aggtggacgg tcttataatg cgattgt 157 <210> 1948 <211> 157 <212> DNA <213> Artificial Sequence <400> 1948 gatgaggtac aagttacctt tgaacgattg agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataactg agtcccttac ctcattcttt gaacgat 157 <210> 1949 <211> 156 <212> DNA <213> Artificial Sequence <400> 1949 caaccctaca tggtttcatg atagactaat gtggaggagg taatataatg ttaataccaa 60 cggaacaaca gcaaatggtc atagacaaat gggaaacaca taatctaaat catagtgagg 120 ttggctctgg caagacactc atggcattag aatcgt 156 <210> 1950 <211> 156 <212> DNA <213> Artificial Sequence <400> 1950 cgcttgcgta acgttctgac cagtttatgt cctcgaactc ataaaagtat gcttcactgt 60 acgcgtttat aagcgcgtca agagggtcaa tcttgttgcg gttaacttgt ttatcaatca 120 taattaaatc gtttgactct tttgtaaatg cgttgt 156 <210> 1951 <211> 156 <212> DNA <213> Artificial Sequence <400> 1951 catttactgc tacaacctca ccatatcccc cagttaggtc cctaaccatt ttagcggttg 60 ttatgtccat ttttagacgc ggtttatcag tgacaatctg tctaaacctt gtgcgtcctc 120 tttcctcatc ataaatcggt gaccttgagg aaaatg 156 <210> 1952 <211> 156 <212> DNA <213> Artificial Sequence <400> 1952 tgtgggtgca tggttttgaa catatcaatc gtaagccacg taggagcctc atagccctct 60 ctaaatcgtt caaaggtaac ttgtacctca tcccatttag aacacctctg agcgtctcta 120 tacgccttta tttgaacatc caaagcgtcc tcaccc 156 <210> 1953 <211> 156 <212> DNA <213> Artificial Sequence <400> 1953 tagcctctcc ctctgtcttt ttagcccgat tgtgttctaa catatgtgtg cgaacgtcag 60 gtttttcaaa aagagggtta gatttaaacc agttttcctc gtcatccgcc tcgtcaaaac 120 tatccatttc ccaccataga gctaagtagt gttcag 156 <210> 1954 <211> 156 <212> DNA <213> Artificial Sequence <400> 1954 ctgaacacta cttagctcta tggtgggaca tggatagttt tgacgaggcg gatgacgagg 60 aaaactggtt taaatctaac cctctttttg aaaaacctga cgttcgcaca catatgttag 120 aacacaaacg ggctaaaaag acagagggag aggcta 156 <210> 1955 <211> 156 <212> DNA <213> Artificial Sequence <400> 1955 ttctgtaggg ttgattttct ttacattttc catacttcta gcctctcctt tttctaattt 60 gtccacgtct tcctctaatg ctttagcacg ttccgcgtcc acagatgtat ctttattttc 120 ttctggttca acctcgtctg cctcatcatc cttagg 156 <210> 1956 <211> 156 <212> DNA <213> Artificial Sequence <400> 1956 catttactgc tacaacctca ccatatccac cagttaggtc cctaaccatt ttagcggttg 60 ttatgtccat ttttagacgc ggtttatcag tgacaatctg tctaaacctt gtgcgtcctc 120 tttcctcctc ataaatcggt gaccttgagg aaaatg 156 <210> 1957 <211> 156 <212> DNA <213> Artificial Sequence <400> 1957 tgtgggtgca tggttttgaa catatcaaac gtaagccacg taggagcctc atagccctct 60 ctaaatcgtt caaaggtaac ttgtacctca tcccatttag aacacctctg agcgtctcta 120 tacgcctgta tttgaacatc caaagcgtcc tcaccc 156 <210> 1958 <211> 156 <212> DNA <213> Artificial Sequence <400> 1958 aatgtctaaa ttagttgcgt catactctag cgtgccctca aacactacgt taaaatatct 60 atcaggtaat gcgtcaaaca ctagtttcat aggttcccta ctcattactt gtgcaactag 120 taaatctttt gtctcactaa tagaaagtcc tgagtg 156 <210> 1959 <211> 156 <212> DNA <213> Artificial Sequence <400> 1959 cactcaggac tttctattag tgagacaata gatttactag ttgcacaagt aatgagtagg 60 gaacctatga aactagtgtt tgacgcatta cctgatagat attttaacgt agtgtttgag 120 ggcacgcaag agtatgacgc aactaattta gacatt 156 <210> 1960 <211> 156 <212> DNA <213> Artificial Sequence <400> 1960 ttaagtccgt tttgtgcgcc taacgtcatt aggtcaaacg cttgcttact atctagaccc 60 cacgagttca taatggcgcc cgcaccgcgt agggtttcat ttacgtctgt atcaaacatc 120 tttgaaatcg ataccgcgta acgtgtaagg ttctgt 156 <210> 1961 <211> 156 <212> DNA <213> Artificial Sequence <400> 1961 cgggctaaaa agacagaggg agaggctaca ggtaatctca ccaacttcct aactaaggag 60 cttaattttt gggttgcgga ccaagcaacg tcatacattt ctgtagacga gtgggaaaag 120 gcgtacacag acgaggagtt tgacatcaca gggcgt 156 <210> 1962 <211> 156 <212> DNA <213> Artificial Sequence <400> 1962 tttgaatgtt ggttctgcca atttagggat ttctactaac tcagctactg tgttcattac 60 cgcgttagtt gtttccaaaa tagggtaaga acctgacgtt gtgctaactg ttactacgtt 120 gatatagttt tgtaggtcta cgattgtctc aggtaa 156 <210> 1963 <211> 156 <212> DNA <213> Artificial Sequence <400> 1963 aatattttac tagaagaaac tgtggcatat aatttgggac tgagagacgc catctttatt 60 agggtgtcag aacttacaaa tattgtaagg gaacacttca caacttacgt atatagtggc 120 atgcttgttg tctccaagtt agagcaattg gatgag 156 <210> 1964 <211> 156 <212> DNA <213> Artificial Sequence <400> 1964 tttgaatgtt ggttctgcca atttagggtt ttctactaac tcagctactg tgttcattac 60 cgcgttagtt gtttccaaaa tagggtaaga acctgacgtt gtgctaactg ttactacgtt 120 gatatagatt tgtaggtcta cgattgtctc aggtaa 156 <210> 1965 <211> 156 <212> DNA <213> Artificial Sequence <400> 1965 cgcttgcgta acgttctgac cagtttattt cctcgaactc ataaaagtat gcttcactgt 60 acgcgtttat aagcgcgtca agagggtcaa tcttgttgcg gttaacttgt ttatcaatca 120 taattaactc gtttgactct tttgtaaatg cgttgt 156 <210> 1966 <211> 156 <212> DNA <213> Artificial Sequence <400> 1966 ttaagtccgt tttgtgcgcc taacgtcagt aggtcaaacg cttgcttact atctagaccc 60 cacgagttca taatggcgcc cgcaccgcgt agggtttcat ttacgtctgt atcaaacatc 120 tttgaaaacg ataccgcgta acgtgtaagg ttctgt 156 <210> 1967 <211> 156 <212> DNA <213> Artificial Sequence <400> 1967 ctcatccaat tgctctaact tggagacacc aagcatgcca ctatatacgt aagttgtgaa 60 gtgttccctt acaatatttg taagttctga caccctaata aagatggcgt ctctcagtcc 120 caaattaaat gccacagttt cttctagtaa aatatt 156 <210> 1968 <211> 156 <212> DNA <213> Artificial Sequence <400> 1968 tagcctctcc ctctgtcttt ttagcccggt tgtgttctaa catatgtgtg cgaacgtcag 60 gtttttcaaa aagagggtta gatttaaacc agttttcctc gtcatccgcc tcgtcaaaac 120 tatccatttc ccaccataga gctaagtagt gttcag 156 <210> 1969 <211> 156 <212> DNA <213> Artificial Sequence <400> 1969 cattttcctc aaggtcaccg atttatgagg aggaaagagg acgcacaagg tttagacaga 60 ttgtcactga taaaccgcgt ctaaaaatgg acataacaac cgctaaaatg gttagggacc 120 taactggggg atatggtgag gttgtagcag taaatg 156 <210> 1970 <211> 156 <212> DNA <213> Artificial Sequence <400> 1970 caaccctaca tggtttcatg atagactatt gtggaggagg taatataatg ttaataccaa 60 cggaacaaca gcaaatggtc atagacaaat gggaaacaca taatctaaat catagtgagg 120 ttggctcagg caagacactc atggcattag aatcgt 156 <210> 1971 <211> 156 <212> DNA <213> Artificial Sequence <400> 1971 cgcttgcgta acgttctgac cagtttatgt cctcgaactc ataaaagtat gcttcactgt 60 acgcgtttat aagcgcgtca agagggtcaa tcttgttgcg gttaacttgt ttatcaatca 120 taattaactc gtttgactct tttgtaaatg cgttgt 156 <210> 1972 <211> 156 <212> DNA <213> Artificial Sequence <400> 1972 ttaagtccgt tttgtgcgcc taacgtcagt aggtcaaacg cttgcttact atctagaccc 60 cacgagttca taatggcgcc cgcaccgcgt agggtttcat ttacgtctgt atcaaacatc 120 tttgaaatcg ataccgcgta acgtgtaagg ttctgt 156 <210> 1973 <211> 156 <212> DNA <213> Artificial Sequence <400> 1973 tagcctctcc ctctgtcttt ttagcccgat tgtgttctaa catatgtgtg cgaacgtcag 60 gtttttcaaa aagagggtta gatttaaacc agttttcctc gtcatccgcc tcgtcaaaac 120 tatccatgtc ccaccataga gctaagtagt gttcag 156 <210> 1974 <211> 156 <212> DNA <213> Artificial Sequence <400> 1974 tgtgggtgca tggttttgaa catatcaatc gtaagccacg taggagcctc atagccctct 60 ctaaatcgtt caaaggtaac ttgtacctca tcccatttag aacacctctg agcgtctcta 120 tacgcctgta tttgaacatc caaagcgtcc tcaccc 156 <210> 1975 <211> 156 <212> DNA <213> Artificial Sequence <400> 1975 cactcaggac tttctattag tgagacaata gatttactag ttgcacaagt aatgagtagg 60 gaacctatga aactagtgtt tgacgcatta cctgatagat attttaacgt agtgtttgag 120 ggcacgctag agtatgacgc aactaattta gacatt 156 <210> 1976 <211> 156 <212> DNA <213> Artificial Sequence <400> 1976 tttgaatgtt ggttctgcca atttagggat ttctactaac tcagctactg tgttcattac 60 cgcgttagtt gtttccaaaa tagggtaaga acctgacgtt gtgctaactg ttactacgtt 120 gatatagatt tgtaggtcta cgattgtctc aggtaa 156 <210> 1977 <211> 156 <212> DNA <213> Artificial Sequence <400> 1977 ctcatccaat tgctctaact tggagacacc aagcatgcca ctatatacgt aagttgtgaa 60 gtgttccctt acaatatttg taagttctga caccctaata aagatggcgt ctctcagtcc 120 caaattatat gccacagttt cttctagtaa aatatt 156 <210> 1978 <211> 156 <212> DNA <213> Artificial Sequence <400> 1978 caaccctaca tggtttcatg atagactatt gtggaggagg taatataatg ttaataccaa 60 cggaacaaca gcaaatggtc atagacaaat gggaaacaca taatctaaat catagtgagg 120 ttggctctgg caagacactc atggcattag aatcgt 156 <210> 1979 <211> 155 <212> DNA <213> Artificial Sequence <400> 1979 tgttggagta ggcagccttt tcgtgcaggt tgatggtatt gatgaatggt tctactatga 60 ccgttttgaa cgtgactatg ttaatgaggg aattgaatat agtttgaaag ataaacatgg 120 tgctaccttg agtgtcgcta ggttatataa agata 155 <210> 1980 <211> 155 <212> DNA <213> Artificial Sequence <400> 1980 gacttcacac acaacccatt ggcgggacca cgtgagataa gttgtgaaga tggtgcactt 60 gacttactta ataatgttgt acctgctatt aaaaccacgt cacctcaatc gtttcaatac 120 tactggaaca ttgtcatgag agacacgggc tttac 155 <210> 1981 <211> 155 <212> DNA <213> Artificial Sequence <400> 1981 agagtggcaa gctcaagaga gttacaaaac attaggtaaa ataagaaaca tgaataaagg 60 ggtcttatgt ggggaacaaa acaaattatt agtagtagac tgtgacgtaa aaggtaaagc 120 aaacggacta cactctttta ctaccttaat gaaag 155 <210> 1982 <211> 155 <212> DNA <213> Artificial Sequence <400> 1982 tcatcaaaga tggagcaaca aacatctaac ccatctaata cagatgagtc tgaggctaga 60 gctttacaaa aagagtcatc ttttgtctca atgtcatatt tgtttacttt tgtaaactca 120 cgaacctgtt tagatttctt tctaacagcc tgtag 155 <210> 1983 <211> 155 <212> DNA <213> Artificial Sequence <400> 1983 taccagggta tttggcaatc accttacgcg ctacattagt aaggtattta tacacacccg 60 ctgtacctac agacgtatct aggctcccgc tctcaaacgc ctcagtaaca cgtgacgtaa 120 gagcgctcgt agctttctta atcattccac gggca 155 <210> 1984 <211> 155 <212> DNA <213> Artificial Sequence <400> 1984 tgtttgatta gagagcgacc ggatggactt gtaagtaaac ctcagattgt aaatatcttg 60 cgtagtaaac cagatacaaa cctaacgtcc tacggttggt tgtatgctat taccatgtat 120 acccttttat atgggtctgc gtttgcaatc attag 155 <210> 1985 <211> 155 <212> DNA <213> Artificial Sequence <400> 1985 gcgtttgata aggttagcag tgttgttggt gacgtttggg actacgcaac taacccaagc 60 aaattagttg aaaaagtatt ctctagcgta gtagacacct caggtctcat aaaatatcct 120 ctagacggtg cccgtggaat gattaagaaa gctac 155 <210> 1986 <211> 155 <212> DNA <213> Artificial Sequence <400> 1986 aaatcatata cgtcaatcat atcctcgtta tactcaaaat catgtaatgt tagttccatt 60 ctattcatcc tcctcaaata agtcatatgt tttaatctct ggtaattttg gcaatttata 120 cgtgctattg tgtcccgtgt ctatcaagtg aaaaa 155 <210> 1987 <211> 155 <212> DNA <213> Artificial Sequence <400> 1987 gatgaggtac aagttacctt tgaacgattt agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataactg agtcccttac ctcattcttt gaacg 155 <210> 1988 <211> 155 <212> DNA <213> Artificial Sequence <400> 1988 tagtaaatcg cctgtaccct gagtcctatt taacccatga aaatatcata ccaataatga 60 acttctgaaa gtctgctagt cctaccctct taccgctttt ggggtctggt aggttgtcaa 120 tgaaagcgat tggtttttct gctaattctg gtcta 155 <210> 1989 <211> 155 <212> DNA <213> Artificial Sequence <400> 1989 gtaaagcccg tgtctctcat gacaatggtc cagtagtatt gaaacgattg aggtgacgtg 60 gttttaatag caggtacaac attattaagt aagtcaagtg caccatcttc acaacttatc 120 tcacgtgttc ccgccaatgg gttgtgtgtg aagtc 155 <210> 1990 <211> 155 <212> DNA <213> Artificial Sequence <400> 1990 tccctcatta acagactcac gttcaaaccg gtcatagtag acccattcat caataccatc 60 aacctgcacg aaaaggctgc ctactccaac catggtatat cgtttacctt tttccaatat 120 ttcttctaca cataaagtgt ctacacatac tactc 155 <210> 1991 <211> 155 <212> DNA <213> Artificial Sequence <400> 1991 acagtgacta caggcaactc aaagcgtggt accctatacg caaccaacga acctctattc 60 tagctgtata tgcaaacaac ggtttagacc taatggaggc agtacagcaa tatgagaaag 120 tacgcgcgga gggaatgcgt ttacaggagc aagaa 155 <210> 1992 <211> 155 <212> DNA <213> Artificial Sequence <400> 1992 gagacaaaca atttagacgt acaaggtatt tgttatgacc ctgcacagtc tcaattaatt 60 accacaagac tagcagacgg gtatgaggac gtactctttg atgtacgtca gtcttatatg 120 cgattaatcc cacctactaa acaattacaa gtgga 155 <210> 1993 <211> 155 <212> DNA <213> Artificial Sequence <400> 1993 tccacttgta attgtttagt aggtgggttt aatcgcatat aagactgacg tacatcaaag 60 agtacgtcct catacccgtc tgctagtctt gtggtaatta attgagactg tgcagggtca 120 taacaaagac cttgtacgtc taaattgttt gtctc 155 <210> 1994 <211> 155 <212> DNA <213> Artificial Sequence <400> 1994 ccaaacgtca aacgggtcaa aagattatta aaaacaacca atggtattat gtaactaaga 60 actcaggtaa gaaaatacct gcctcaggat gggtcagtgg atattaccta caaaacccta 120 aacgtgtgga acacaagaag aaagagacct actct 155 <210> 1995 <211> 155 <212> DNA <213> Artificial Sequence <400> 1995 gttccgctgt acaatgacac gtgaccaaac gggtaagaag ttcacttgga actttgagca 60 tatccaatca aacaacggaa ttaaaccagt tacaaaaaac ccatttacct acaatgcacc 120 tgtagcacac aaagcttccg ttgttaaaac atcta 155 <210> 1996 <211> 155 <212> DNA <213> Artificial Sequence <400> 1996 tctacagaac aataatatgt atatacattt gattgtcctg catttactgt gattgttttt 60 cctgttgctg tccatgatgt gtctaatacg tttgaggcgt catatctacg ccatacaaac 120 gaagtaatat tatcagtaat gtcatccttg ccttt 155 <210> 1997 <211> 155 <212> DNA <213> Artificial Sequence <400> 1997 cgttgttata ctagctcata cgcaacatca aggttaccta aatcattttt agcaatctta 60 acaataacaa actcatcctc aacttcatcc tgttccccat ccacgcgtat agtcactttc 120 ttttctagtt cttgctcctg taaacgcatt ccctc 155 <210> 1998 <211> 155 <212> DNA <213> Artificial Sequence <400> 1998 gatgaggtac aagttacctt tgaacgaatt agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataaatg agtcccttac ctcattcttt gaacg 155 <210> 1999 <211> 155 <212> DNA <213> Artificial Sequence <400> 1999 tagatgtttt aacaacggaa gctttgtttg ctacaggtgc attgtaggta aatgggtttt 60 ttgtaactgg tttaattccg ttgtttgatt ggatatgctc aaagttccaa gtgaacttct 120 tacccgtgtg gtcacgtgtc attgtacagc ggaac 155 <210> 2000 <211> 155 <212> DNA <213> Artificial Sequence <400> 2000 tagcaccatc accaatggtt gtggactttg gtacttttat tacagggcaa tcactagacg 60 agattgaaca tttaaaaaat tctgacattt acacagcaac aaacattatc agtggcgata 120 ttgctaactg tttgattaga gagcgaccgg atgga 155 <210> 2001 <211> 155 <212> DNA <213> Artificial Sequence <400> 2001 ttttgtattg gctgtagaat atatttgacg ggacgccatt ggcgaacgtt cgtaaagaag 60 ttcatataat gcaatacccg cgattaataa tgatttaccg ttcttacgac tcatggagat 120 taccactata gtaaatcgcc tgtaccctga gtcct 155 <210> 2002 <211> 155 <212> DNA <213> Artificial Sequence <400> 2002 aaatcatata cgtcaatcat atcctcggta tactcaaaat catgtaatgt tagttccatt 60 ctattcatcc tcctcaaata agtcatatgt tttaatctct ggtaattttg gcaatttata 120 cgtgctaatg tgtcccgtgt ctatcaagtg aaaaa 155 <210> 2003 <211> 155 <212> DNA <213> Artificial Sequence <400> 2003 aaaggcaagg atgacattac tgataatttt acttcgtttg tatggcgtag atatgacgcc 60 tcaaacgtat tagacacatc atggacagca acaggaaaaa caatcacagt aaatgcagga 120 caatcaactg tatatacata ttattgttct gtaga 155 <210> 2004 <211> 155 <212> DNA <213> Artificial Sequence <400> 2004 tgtttaacga ctcatcaact aacagaatag tctattatag caatgactta ttaaccaact 60 acttgccagc aggagttaaa tattccgtca caatagacgc attcagcaac aataatgggt 120 taattagtgt aggtaatttt gacgctctca gtaca 155 <210> 2005 <211> 155 <212> DNA <213> Artificial Sequence <400> 2005 tgtttaacga ctcatcaact aacagaagag tctattatag caatgactta ttaaccaact 60 acttgccagc aggagttaaa tattccgtca caatagacgc attcagcaac aataatgggt 120 taattagtgt aggtaatttt gacgctctca gtaca 155 <210> 2006 <211> 155 <212> DNA <213> Artificial Sequence <400> 2006 gtaaagcccg tgtctctcat gacaatggtc cagtagtatt gaaacgattg aggtgacgtg 60 gttttaatag caggtacaac attattaagt aagtcaagtg caccatcttc acaacttatc 120 tcacgtggtc ccgccaatgg gttgtgtgtg aagtc 155 <210> 2007 <211> 155 <212> DNA <213> Artificial Sequence <400> 2007 tagatgtttt aacaacggaa gctttgtgtg ctacaggtgc attgtaggta aatgggtttt 60 ttgtaactgg tttaattccg ttgtttgatt ggatatgctc aaagttccaa gtgaacttct 120 tacccgtgtg gtcacgtgtc attgtacagc ggaac 155 <210> 2008 <211> 155 <212> DNA <213> Artificial Sequence <400> 2008 aaatcatata cgtcaatcat atcctcggta tactcaaaat catgtaatgt tagttccatt 60 ctattcatcc tcctcaaata agtcatatgt tttaatctct ggtaattttg gcaatttata 120 cgtgctattg tgtcccgtgt ctatcaagtg aaaaa 155 <210> 2009 <211> 155 <212> DNA <213> Artificial Sequence <400> 2009 tccacttgta attgtttagt aggtgggatt aatcgcatat aagactgacg tacatcaaag 60 agtacgtcct catacccgtc tgctagtctt gtggtaatta attgagactg tgcagggtca 120 taacaaagac cttgtacgtc taaattgttt gtctc 155 <210> 2010 <211> 155 <212> DNA <213> Artificial Sequence <400> 2010 tctacagaac aataatatgt atatacagtt gattgtcctg catttactgt gattgttttt 60 cctgttgctg tccatgatgt gtctaatacg tttgaggcgt catatctacg ccatacaaac 120 gaagtaatat tatcagtaat gtcatccttg ccttt 155 <210> 2011 <211> 155 <212> DNA <213> Artificial Sequence <400> 2011 ctttcattaa ggtagtaaaa gagtgtagtc cgtttgcttt accttttacg tcacagtcta 60 ctactaataa tttgttttgt tccccacata agaccccttt attcatgttt cttattttac 120 ctaatgtatt gtaactctct tgagcttgcc actct 155 <210> 2012 <211> 155 <212> DNA <213> Artificial Sequence <400> 2012 gatgaggtac aagttacctt tgaacgaatt agagagggct atgaggctcc tacgtggctt 60 acgtttgata tgttcaaaac catgcaccca catttagcca atgtgaatgt aactcagtca 120 aaaataactg agtcccttac ctcattcttt gaacg 155 <210> 2013 <211> 154 <212> DNA <213> Artificial Sequence <400> 2013 ttaacatatc ctcccaatca cactgaccgt caggacggga cgaaatttca caatacccct 60 gtttggaata ttgtctatag ggtgttctat cgttagcctc tttctgaaca ataccaccac 120 ccgttgttgc tacccacgcg tgagagtcaa caat 154 <210> 2014 <211> 154 <212> DNA <213> Artificial Sequence <400> 2014 atagcgtaag tattacaata aatgactagc atgccagcgt ctagttttga aattggtagc 60 tgtttaagtt gtggaacaag gtcctcgtaa atcaaccacc cttccttagt aagtccctca 120 ggaatatcgt ctaatgaaag ttgttcataa ttat 154 <210> 2015 <211> 154 <212> DNA <213> Artificial Sequence <400> 2015 ttctatcgtt gaaatatccc tctttaaatt gagggttacc tttgacaagt tcgtatacct 60 tgtccccaac tttacctaag aacgtaccta ctttattatc actatcacca cttttaaact 120 cttgcgcgtg tgggtaaatg acagagtata gtag 154 <210> 2016 <211> 154 <212> DNA <213> Artificial Sequence <400> 2016 acctgaacca actgaatttt ttatgactga gggttacgag cgtgacaggg aatacgttgg 60 agaggtgttc agagtagctc atagcgctga agaaattgac ggacaaacgc accaacttga 120 actaagtatt gatggtcacc tatggtgggt atat 154 <210> 2017 <211> 154 <212> DNA <213> Artificial Sequence <400> 2017 gtgaacctcc tccaattata acttctttat aaattataac acgaaaaaga caaccctagt 60 tgggttgcct cgttcgttta ttacagtcca aaaccaaaat caccgcttgc gtaacgttct 120 gaccagtgta tttcctcgaa ctcataaaag tatg 154 <210> 2018 <211> 154 <212> DNA <213> Artificial Sequence <400> 2018 ggtgctttga caggcgttgt aagggacggt cctgaccatg cgtttggtgc gaatgttgta 60 gcccacttag gtttaaacgc ctcagaaggg ctgtagtccc atgaacccat gtagaggttt 120 ggtctagcag ggtcgttaga cgtatttggg tact 154 <210> 2019 <211> 154 <212> DNA <213> Artificial Sequence <400> 2019 attttatgac catcaatcag gtaactgatt aggacgaaca aagacaggta ccctacaatt 60 aaacacagac gacagcggtt taaagttccg tctacaatta ccaaataccc aattaggtag 120 agacgtctat gagttagtaa aacgcggtga ccta 154 <210> 2020 <211> 154 <212> DNA <213> Artificial Sequence <400> 2020 ctactatact ctgtcattta cccacaagcg caagagttta aaagtggtga tagtgataat 60 aaagtaggta cgttcttagg taaagttggg gacaaggtat acgaacttgt caaaggtaac 120 cctcaatgta aagagggata tttcaacgat agaa 154 <210> 2021 <211> 154 <212> DNA <213> Artificial Sequence <400> 2021 tcaccttaat cataattaac catcccgtgt ctttattggt tggtactcgt tcaccccgta 60 ggcttaaccc tcaaccttat gaacctagta taaacaatta aactctaata gtcaattaaa 120 aaaccattag agtttaatga gaatattcta ttta 154 <210> 2022 <211> 154 <212> DNA <213> Artificial Sequence <400> 2022 attttatgac catcaatcag gtaacttatt aggacgaaca aagacaggta ccctacaatt 60 aaacacagac gacagcggtt taaagttccg tctacaatta ccaaataccc aattaggtag 120 agacgtcgat gagttagtaa aacgcggtga ccta 154 <210> 2023 <211> 154 <212> DNA <213> Artificial Sequence <400> 2023 atcacaagag cagttagtta aagttataga aatggcgcag ttgggtaatt atctaattta 60 tagacgacat aacggagata gtgcctgtct tactatcatg gacttcacac acaacccatt 120 ggcgggaaca cgtgagataa gttgtgaaga tggt 154 <210> 2024 <211> 154 <212> DNA <213> Artificial Sequence <400> 2024 tcaccttaat cataattaac catcccttgt ctttattggt tggtactcgt tcaccccgta 60 ggcttaaccc tcaaccttat gaacctagta taaacaatta aactctaata gtcaattaaa 120 aaaccatgag agtttaatga gaatattcta ttta 154 <210> 2025 <211> 154 <212> DNA <213> Artificial Sequence <400> 2025 cgttttaaca gcagaagaaa ctgcacaagt gttaggtcat aaacgtccta agtttgcata 60 caaaaaaggt actggcttct ttgacaaaat tacaggaggc gtaaaaatca tctggaacgg 120 tgccaaaaac atggctaaaa gtgcgtttga taag 154 <210> 2026 <211> 154 <212> DNA <213> Artificial Sequence <400> 2026 ctatagacat taatatgtca ttagcgtctg tcaaaataac caactcataa cgtccgttct 60 tttctgacgt agtaccgaag tctatccgtt cctcaaattt aaaggctcct gttcgtaaac 120 ctgttgaggg tgctttgaca ggcgttgtaa ggga 154 <210> 2027 <211> 154 <212> DNA <213> Artificial Sequence <400> 2027 gccactatca gtggtgaggg tagacattga gttaaaagat gggttctata atttaggtaa 60 gcctgaaatt gcaggcaagg ttgatgaagt tccaccgcgt cccaataaac caagcgggaa 120 acaatatgta gtaatttatg atattgaggt attt 154 <210> 2028 <211> 154 <212> DNA <213> Artificial Sequence <400> 2028 ctgttacgtg ggttattcct atccctgaaa aagaattgtt tattgttgac tctcacgcgt 60 gggtagcaac aacgggtggt ggtattgttc agaaagaggc taacgataga acaccctata 120 gacaatagtc caaacagggg tattgtgaaa tttc 154 <210> 2029 <211> 154 <212> DNA <213> Artificial Sequence <400> 2029 taatgacata ttaatgtcta tagccaaccg tgactctgac gcaaaaggca atgaagtgat 60 tgttgaatac tggtacggta acaagttact aaaatctatc aagacagacg taactaagta 120 caaatcatct tggttccgct gtacaatgac acgt 154 <210> 2030 <211> 154 <212> DNA <213> Artificial Sequence <400> 2030 taatgacata ttaatgtcta tagccatccg tgactctgac gcaaaaggca atgaagtgat 60 tgttgaatac tggtacggta acaagttact aaaatctatc aagacagacg taactaagta 120 caaatcaact tggttccgct gtacaatgac acgt 154 <210> 2031 <211> 154 <212> DNA <213> Artificial Sequence <400> 2031 tcataaaaaa ttcagttggt tcaggtgtaa tcaagcgcac cttcgtcccc actggtaggg 60 gtttagtaaa attatcctca aatactttac tcattttgtt ttcctccctt tatcctaata 120 catcgtcaat acggtctgaa atcgtgtctc tatc 154 <210> 2032 <211> 154 <212> DNA <213> Artificial Sequence <400> 2032 gtgaacctcc tccaattata acttctatat aaattataac acgaaaaaga caaccctagt 60 tgggttgcct cgttcgttta ttacagtcca aaaccaaaat caccgcttgc gtaacgttct 120 gaccagttta tttcctcgaa ctcataaaag tatg 154 <210> 2033 <211> 154 <212> DNA <213> Artificial Sequence <400> 2033 ttctatcgtt gaaatatccc tctttacatt gagggttacc tttgacaagt tcgtatacct 60 tgtccccaac tttacctaag aacgtaccta ctttattatc actatcacca cttttaaact 120 cttgcgcgtg tgggtaaatg acagagtata gtag 154 <210> 2034 <211> 154 <212> DNA <213> Artificial Sequence <400> 2034 atcacaagag cagttagtta aagttataga aatggcgcag ttgggtaatt atctaattta 60 tagacgacat aacggagata gtgcctgtct tactatcatg gacttcacac acaacccatt 120 ggcgggacca cgtgagataa gttgtgaaga tggt 154 <210> 2035 <211> 154 <212> DNA <213> Artificial Sequence <400> 2035 tcaccttaat cataattaac catcccgtgt ctttattggt tggtactcgt tcaccccgta 60 ggcttaaccc tcaaccttat gaacctagta taaacaatta aactctaata gtcaattaaa 120 aaaccatgag agtttaatga gaatattcta ttta 154 <210> 2036 <211> 154 <212> DNA <213> Artificial Sequence <400> 2036 gccactatca gtggtgaggg tagacagtga gttaaaagat gggttctata atttaggtaa 60 gcctgaaatt gcaggcaagg ttgatgaagt tccaccgcgt cccaataaac caagcgggaa 120 acaatatgta gtaatttatg atattgaggt attt 154 <210> 2037 <211> 154 <212> DNA <213> Artificial Sequence <400> 2037 taatgacata ttaatgtcta tagccaaccg tgactctgac gcaaaaggca atgaagtgat 60 tgttgaatac tggtacggta acaagttact aaaatctatc aagacagacg taactaagta 120 caaatcaact tggttccgct gtacaatgac acgt 154 <210> 2038 <211> 154 <212> DNA <213> Artificial Sequence <400> 2038 catactttta tgagttcgag gaaatacact ggtcagaacg ttacgcaagc ggtgattttg 60 gttttggact gtaataaacg aacgaggcaa cccaactagg gttgtctttt tcgtgttata 120 atttatatag aagttataat tggaggaggt tcac 154 <210> 2039 <211> 154 <212> DNA <213> Artificial Sequence <400> 2039 taggtcaccg cgttttacta actcatcgac gtctctacct aattgggtat ttggtaattg 60 tagacggaac tttaaaccgc tgtcgtctgt gtttaattgt agggtacctg tctttgttcg 120 tcctaatcag ttacctgatt gatggtcata aaat 154 <210> 2040 <211> 153 <212> DNA <213> Artificial Sequence <400> 2040 ttggcgatta tattaaaacc atcacggagt tattatggaa tatgggcgcc atcatgtttg 60 aaaaggttta tccattatta aaacccatac tagacacgat ttttagtgcg ttcggtagca 120 ttttcaatca ggtaagcgag ttctataatc agt 153 <210> 2041 <211> 153 <212> DNA <213> Artificial Sequence <400> 2041 attatgctac aattgacaaa aaaggattta gtggtggtta tcaccttaaa caaacactaa 60 attaggggag gaatttaaat gaacacatat acagtttatt accgtaacat tgatgagcac 120 tattgctgta gtattcacgt tgacgcatat act 153 <210> 2042 <211> 153 <212> DNA <213> Artificial Sequence <400> 2042 tggcggtcac cctgtagatg gtcccatgac tgtcaatgat ggacgtggtg ctgaaatggt 60 tattgaccca agtggtcaag cggttatccc taaaggtaag aacgtaacga tgtggggacg 120 aaaaggaccc cacgttttaa cagcagaaga aac 153 <210> 2043 <211> 153 <212> DNA <213> Artificial Sequence <400> 2043 tcgacttaca agcgggtgga gcatatagtg ctgttttagg tattaccgca gacgaaaatg 60 gtattatgac agtggggcag gacactcaag ctccttatgt ctctgttact attgtatcag 120 atgacgcaga tggtaatgag gtatatatgg gac 153 <210> 2044 <211> 153 <212> DNA <213> Artificial Sequence <400> 2044 taactttgat tgtatgctag tctatttatc attttactca tgtagtcaac ttggttctgt 60 aacgtgtcta ctgcgttatc ttgagtgcta tatccgttta gttcataaat gaggtcgtcc 120 atggctatcg cgttgccatg gaactcctcc tct 153 <210> 2045 <211> 153 <212> DNA <213> Artificial Sequence <400> 2045 tatgattaag gtgatgaatt gggagtatga atatggaatg aaacgagtag cattctacaa 60 agaaattggt catgagattg agcttttaga tagagaaaaa tgtatacact tttatagaga 120 cggacgtgat tatgctacaa ttgacaaaaa agg 153 <210> 2046 <211> 153 <212> DNA <213> Artificial Sequence <400> 2046 tttatcaagg ttgaacatgg cacaaataaa cgctttagca agtaacccat caacacaacc 60 atagaagcgt agctcagtgg cgtctacgtc tttccaacaa taagcaacct ctttgcgtag 120 ttcctcagct gttagtttac cgccttgttc aaa 153 <210> 2047 <211> 153 <212> DNA <213> Artificial Sequence <400> 2047 gtgtcacctt gttttattgt ttgccatgta ctgagagcgt caaaattacc taccctaatt 60 aacccattat tgttgctgaa tgcgtctatt gtgacggaat atttaactcc tgctggcaag 120 tagttggata ataagtcatt gctataatag act 153 <210> 2048 <211> 153 <212> DNA <213> Artificial Sequence <400> 2048 taactttgat tgtatgctag tctatgtatc attttactca tgtagtcaac ttggttctgt 60 aacgtgtcta ctgcgttatc ttgagtgcta tatccgttta gttcataaat gaggtcgtcc 120 atggctaacg cgttgccatg gaactcctcc tct 153 <210> 2049 <211> 153 <212> DNA <213> Artificial Sequence <400> 2049 tgtaacatgg taacatggtc cctaattccc tcgtagaagt cagccataat taattgccca 60 atcacacatg ttagaaattg aaaacgtggg tcatataacc cattaaactc tgcacctgtg 120 gcaccaacca atgtattaat aggcaatttt acc 153 <210> 2050 <211> 153 <212> DNA <213> Artificial Sequence <400> 2050 tggcggtcac cctgtagatg gtcccctgac tgtcaatgat ggacgtggtg ctgaaatggt 60 tattgaccca agtggtcaag cggttatccc taaaggtaag aacgtaacga tgtggggacg 120 aaaaggaacc cacgttttaa cagcagaaga aac 153 <210> 2051 <211> 153 <212> DNA <213> Artificial Sequence <400> 2051 tgtaacatgg taacatggtc cctaagtccc tcgtagaagt cagccataat taattgccca 60 atcacacatg ttagaaattg aaaacgtggg tcatataacc cattaaactc tgcacctgtg 120 gcaccaacca atgtattaat aggcaatttt acc 153 <210> 2052 <211> 153 <212> DNA <213> Artificial Sequence <400> 2052 tttgaacaag gcggtaaact aacagctgag gaactacgca aagaggttgc ttattgttgg 60 aaagacgtag acgccactga gctacgcttc tatggttgtg ttgatgggtt acttgctaaa 120 gcgtttaatt gtgccatgtt caaccttgat aaa 153 <210> 2053 <211> 153 <212> DNA <213> Artificial Sequence <400> 2053 taactttgat tgtatgctag tctatgtatc attttactca tgtagtcaac ttggttctgt 60 aacgtgtcta ctgcgttatc ttgagtgcta tatccgttta gttcataaat gaggtcgtcc 120 atggctatcg cgttgccatg gaactcctcc tct 153 <210> 2054 <211> 153 <212> DNA <213> Artificial Sequence <400> 2054 tttgaacaag gcggtaaact aacagatgag gaactacgca aagaggttgc ttattgttgg 60 aaagacgtag acgccactga gctacgcttc tatggttgtg ttgatgggtt acttgctaaa 120 gcgtttaatt gtgccatgtt caaccttgat aaa 153 <210> 2055 <211> 153 <212> DNA <213> Artificial Sequence <400> 2055 caggtaagcg agttctataa tcagtctggt aaacaaatca tggaagcgtt catgaacttc 60 cttaatttta ttagtccact actaaaaatt gtaattggtt tagttggtga ctttgtcaac 120 aatgttatcg ggttcattca aggtatggtt gac 153 <210> 2056 <211> 153 <212> DNA <213> Artificial Sequence <400> 2056 agtctactac taataatttg ttttggtccc cacataagac ccctttattc atgtttctta 60 ttttacctaa tgtattgtaa ctctcttgag cttgccactc ttttatcgcg ggaattttag 120 tacgcgcttt gagaggaaac cccttaaatt ggt 153 <210> 2057 <211> 153 <212> DNA <213> Artificial Sequence <400> 2057 gtttcttctg ctgttaaaac gtggggtcct tttcgtcccc acatcgttac gttcttacct 60 ttagggataa ccgcttgacc acttgggtca ataaccattt cagcaccacg tccatcattg 120 acagtcaggg gaccatctac agggtgaccg cca 153 <210> 2058 <211> 152 <212> DNA <213> Artificial Sequence <400> 2058 ttgtaccatc agtgtactcc cacgttgtac gtgtccatag gtatttacct ttttctagag 60 ttgggatggt tgtactccat cctgatgtag gttcatcaac gcttgaggta ttgattgccc 120 actctgtgtt agttgatttg acagaggcgc ca 152 <210> 2059 <211> 152 <212> DNA <213> Artificial Sequence <400> 2059 tgggactaca gcccttctga ggcgattaaa cctaagtggg ctacaacatt cgcaccaaac 60 gcatggtcag gaccttccct tacaacgcct gtcaaagcac catcaacagg tttacgaaca 120 ggagccttta aatttgagga acggatagac tt 152 <210> 2060 <211> 152 <212> DNA <213> Artificial Sequence <400> 2060 ttctagtaag taggtatggt actacagtag atagtgcgat tccgtcaggc gcatggataa 60 acatctcttg cgtatatgcg ggtcaagatt tattctatgg gggataatta tgttagagca 120 atttaaaacg gagtatatta acaaggtatt aa 152 <210> 2061 <211> 152 <212> DNA <213> Artificial Sequence <400> 2061 gtcctctttt accattttac gcgtgattct acttctatca tctgtgttgt atctgtttgc 60 tagaagaata ccgtccgtga agagtttcaa ttcaacaagg tcaccctcat tacccgtgtg 120 ctcaaatagt ccactattaa aggctaaatc aa 152 <210> 2062 <211> 152 <212> DNA <213> Artificial Sequence <400> 2062 tttgaactaa tttgttcata tacgttctca tagaggttgg tttcactgtt gaacgtaaca 60 gcgtaaccct caacaatcat gtcctcattt tcctcaagtg ctctaatctc aatgctacgc 120 gtctccgatt tcatcattag tagcctcctt at 152 <210> 2063 <211> 152 <212> DNA <213> Artificial Sequence <400> 2063 ttaaacccac tcacgtacac acgtggaccc gctacagtat tcaagtcatc tacgtggtgt 60 tgcttagggt tcgtgcatat tgccttaata cgcgaacgtt taccctcatt gtacatatag 120 tccctcaggt cctcttttac cattttacgc gt 152 <210> 2064 <211> 152 <212> DNA <213> Artificial Sequence <400> 2064 ggcactgacc ctaatactga tacttttgag gggtctgcta ttagtgactc acgtggatat 60 gtatacgcct ctggtgtgaa gtctgagacg ttgacgcttg agaaattcca agactttgta 120 gcaaacaaaa caacgccagt tggacagtaa ag 152 <210> 2065 <211> 152 <212> DNA <213> Artificial Sequence <400> 2065 tttgaactaa tttgttcata tacggtctca tagaggttgg tttcactgtt gaacgtaaca 60 gcgtaaccct caacaatcat gtcctcattt tcctcaagtg ctctaatctc aatgctacgc 120 gtctccgttt tcatcattag tagcctcctt at 152 <210> 2066 <211> 152 <212> DNA <213> Artificial Sequence <400> 2066 tacaccccaa acccatctga agatttcgcg aacgcatatc cgctatatat gggtcaatat 60 agtaactata ctcaagaacc tagcacggac ccaagtaagt acacgtggat gagaacaacg 120 ggacaaactg gcgcctctgt caaatcaact aa 152 <210> 2067 <211> 152 <212> DNA <213> Artificial Sequence <400> 2067 cgcaaccaac gaacctctat tctagctgta tatgcaaaca acggtttaga cctaatggag 60 gcagtacagc aagatgagaa agtacgcgct gagggaatgc gtttacagga gcaagaaata 120 gaaaagaaag tgactatacg cgtggatggg ga 152 <210> 2068 <211> 152 <212> DNA <213> Artificial Sequence <400> 2068 ttaacgactc atcaactaac agaagagtct attatagcaa tgacttatta accaactact 60 tgccagcagg agttaaatat tccgtcacaa tagacgcatt cagcaacaat aatgggttaa 120 ttagggtcgg taattttgac gctctcagta ca 152 <210> 2069 <211> 152 <212> DNA <213> Artificial Sequence <400> 2069 tatagtgaat atatgaaaat tcacagcggt tatgatacgt ataataatgg ttcctataga 60 catttgtcag ttcgccaaaa tacagagttc gccactaaat acttgtcaga gggtggtacg 120 agtattcttt tacaccagag tggtagttat ta 152 <210> 2070 <211> 152 <212> DNA <213> Artificial Sequence <400> 2070 gttcacactc caatacccaa atgataattt agtattgaat tatgatttct cgaaagaccc 60 cactattaat ggttggacag gaaatggtgc gactatagaa tattcaaacg ggaacatgcg 120 agtgttgatt aacgactcat caactaacag aa 152 <210> 2071 <211> 152 <212> DNA <213> Artificial Sequence <400> 2071 tatagtgaat atatgaaaat tcactgcggt tatgatacgt ataataatgg ttcctataga 60 catttgtcag ttcgccaaaa tacagagttc gccactaaat acttgtcaga gggtggtacg 120 agtattcatt tacaccagag tggtagttat ta 152 <210> 2072 <211> 152 <212> DNA <213> Artificial Sequence <400> 2072 ggcactgacc ctaatactga tactattgag gggtctgcta ttagtgactc acgtggatat 60 gtatacgcct ctggtgtgaa gtctgagacg ttgacgcttg agaaattcca agactttgta 120 gcaaacacaa caacgccagt tggacagtaa ag 152 <210> 2073 <211> 152 <212> DNA <213> Artificial Sequence <400> 2073 tgggactaca gcccttctga ggcgtttaaa cctaagtggg ctacaacatt cgcaccaaac 60 gcatggtcag gaccttccct tacaacgcct gtcaaagcac catcaacagg tttacgaaca 120 ggagcctata aatttgagga acggatagac tt 152 <210> 2074 <211> 152 <212> DNA <213> Artificial Sequence <400> 2074 taataactac cactctggtg taaaagaata ctcgtaccac cctctgacaa gtatttagtg 60 gcgaactctg tattttggcg aactgacaaa tgtctatagg aaccattatt atacgtatca 120 taaccgcagt gaattttcat atattcacta ta 152 <210> 2075 <211> 152 <212> DNA <213> Artificial Sequence <400> 2075 tgggactaca gcccttctga ggcgattaaa cctaagtggg ctacaacatt cgcaccaaac 60 gcatggtcag gaccttccct tacaacgcct gtcaaagcac catcaacagg tttacgaaca 120 ggagcctata aatttgagga acggatagac tt 152 <210> 2076 <211> 152 <212> DNA <213> Artificial Sequence <400> 2076 ggcactgacc ctaatactga tacttttgag gggtctgcta ttagtgactc acgtggatat 60 gtatacgcct ctggtgtgaa gtctgagacg ttgacgcttg agaaattcca agactttgta 120 gcaaacacaa caacgccagt tggacagtaa ag 152 <210> 2077 <211> 152 <212> DNA <213> Artificial Sequence <400> 2077 tttgaactaa tttgttcata tacggtctca tagaggttgg tttcactgtt gaacgtaaca 60 gcgtaaccct caacaatcat gtcctcattt tcctcaagtg ctctaatctc aatgctacgc 120 gtctccgatt tcatcattag tagcctcctt at 152 <210> 2078 <211> 151 <212> DNA <213> Artificial Sequence <400> 2078 atgtatttta tttttgacca tgaggaatat attgagtcaa aatttgaact gaaagaaaag 60 gaggctgtaa aggaaacggg aattgtacac aaagccaaaa tgtacgtgcg tttgaaaatt 120 ttcccaatgg atggctctaa cgcgcgcgta a 151 <210> 2079 <211> 151 <212> DNA <213> Artificial Sequence <400> 2079 tcctctttgt ttaggttctc accgtccccc tctattgctc ccgttgcctt acctgtgttc 60 atgtctacag ccaaaataag taaatcagta tgaatgttca ttatttttcc tcctcaaatt 120 taattagcgt atctaaatac acacgtgcct t 151 <210> 2080 <211> 151 <212> DNA <213> Artificial Sequence <400> 2080 acacaggtaa ggcaacggga gcactagagg gggaaggtga gaacctaaac aaagaggaaa 60 caattgagct attagaaggg gttgtcaagt tcttacgcga agaacttagt atgttagatg 120 aggaggaaaa cgaagatgaa taactatgag t 151 <210> 2081 <211> 151 <212> DNA <213> Artificial Sequence <400> 2081 acgttgtacc gcgcaaagca ctgtagccat ttgataggta tgcaggacgt attgttgaca 60 ctgctgtttt agttaattta gtggctcctg ctgttggtgt agccgttact gcgtcaaaga 120 gtccccaata ctgtatacta ttgtcctgtg a 151 <210> 2082 <211> 151 <212> DNA <213> Artificial Sequence <400> 2082 ttagctagta actcagtcat tactgcttta ttgattgtgt tcaacccaat acgtgttaag 60 tggcgagcaa tcaacgcaac taagtcaggg tcagagtctt gaattgcttc gttagacatt 120 ggaatatctc cgcggtgtgt ttctaccttc c 151 <210> 2083 <211> 151 <212> DNA <213> Artificial Sequence <400> 2083 aggggtcaat atggtcagaa ccagtgtttg gttgatgtgc cgttgcatat gcgtgagaaa 60 tgacacctgt attcccttgg tctagcgtct taggtagtcc cgcttcatca cataatagac 120 gaattaattc tactagtagc ttatagtctt t 151 <210> 2084 <211> 151 <212> DNA <213> Artificial Sequence <400> 2084 ggtgagaacc taaacaaaga ggacacaatt gagctattag aaggggttgt caagttctta 60 cgcgaagaac ttagtatgtt agatgaggag gaaaacgaag atgaataact atgagttatt 120 agtagaagtt gaaaacacag accgtatttt a 151 <210> 2085 <211> 151 <212> DNA <213> Artificial Sequence <400> 2085 atcattagac gcaacggaac acaagttact aagctacaga ttgtcagccc tcatacaatt 60 acaatcttac aagacacagc gagtaaagaa ttgtcatatg agtacattga ccctgacaat 120 caaaagacag aaaccatcaa gggtaaagac a 151 <210> 2086 <211> 151 <212> DNA <213> Artificial Sequence <400> 2086 actcatagtt attcatcttc gttgtcctcc tcatctaaca tactaagttc ttcgcgtaag 60 aacttgacaa ccccttctaa tagctcaatt gtttcctctt tgtttaggtt ctcaccttcc 120 ccctctattg ctcccgttgc cttacctgtg t 151 <210> 2087 <211> 151 <212> DNA <213> Artificial Sequence <400> 2087 ctcagcttca gcaacgtttt ctgtagggtt gattttcttt acattttcca tacttctagc 60 ctctcctttt tctaatttgt ccacgtcttc ctctaatgct ttagcacgtt ccgcgtccac 120 agatttagct ttattttctt ctggttcaac c 151 <210> 2088 <211> 151 <212> DNA <213> Artificial Sequence <400> 2088 tatcacctta aacaaacact aaattagggg aggaatttaa atgaacacat atacagttta 60 ttaccgtaac attgatgagc actattgctg tagtattcac gttgacgcat atactattga 120 acaagctctt aataaagggt tacagtacct t 151 <210> 2089 <211> 151 <212> DNA <213> Artificial Sequence <400> 2089 tccgcggtgt gtttctacct tcccttctac atttttgaat gttggttctg ccaatttagg 60 gttttctact aactcagcta ctgtgttcat taccgcgtta gttgtttcca aaatagggta 120 agaacctgac gttgtgctaa ctgttactac g 151 <210> 2090 <211> 151 <212> DNA <213> Artificial Sequence <400> 2090 ggttgaacca gaagaaaata aagataaatc tgtggacgcg gaacgtgcta aagcattaga 60 ggaagacgtg gacaaattag aaaaaggaga ggctagaagt atggaaaatg taaagaaaat 120 caaccctcca gaaaacgttg ctgaagctga g 151 <210> 2091 <211> 151 <212> DNA <213> Artificial Sequence <400> 2091 aggggtcaat atggtcagaa ccattgtttg gttgatgtgc cgttgcatat gcgtgagaaa 60 tgacacctgt attcccttgg tctagcgtct taggtagtcc cgcttcatca cataatagac 120 gaattaagtc tactagtagc ttatagtctt t 151 <210> 2092 <211> 151 <212> DNA <213> Artificial Sequence <400> 2092 tatcacctta aacaaacact aaagtagggg aggaatttaa atgaacacat atacagttta 60 ttaccgtaac attgatgagc actattgctg tagtattcac gttgacgcat atactattga 120 acaagctatt aataaagggt tacagtacct t 151 <210> 2093 <211> 151 <212> DNA <213> Artificial Sequence <400> 2093 gttgatggta ttgatgaatg gttatactat gaccgttttg aacgtgacta tgttaatgag 60 ggaattgaat atagtttgaa agataaacat ggtgctacct tgagtgtcgc taggttatat 120 aaagataaaa cagtgattaa aattactgat t 151 <210> 2094 <211> 151 <212> DNA <213> Artificial Sequence <400> 2094 aatcagtaat tttaatcact gttgtatctt tatataacct agcgacactc aaggtagcac 60 catgtttatc tttcaaacta tattcaattc cctcattaac atagtcacgt tcaaaacggt 120 catagtagaa ccattcatca ataccatcaa c 151 <210> 2095 <211> 151 <212> DNA <213> Artificial Sequence <400> 2095 gatacctttt ttaaagtaac tacctaacaa acgtgttccg cttgtttgca tatctatttc 60 aggtactagc gcttttagtg gtgagcgtcc tgaaatgccg tcaattgagt tcagtctaaa 120 atgtaacttg tctttaccct tgatggtttc t 151 <210> 2096 <211> 151 <212> DNA <213> Artificial Sequence <400> 2096 actcatagtt attcatcttc gttgtcctcc tcatctaaca tactaagttc ttcgcgtaag 60 aacttgacaa ccccttctaa tagctcaatt gtttcctctt tgtttaggtt ctcaccttcc 120 ccctctagtg ctcccgttgc cttacctgtg t 151 <210> 2097 <211> 151 <212> DNA <213> Artificial Sequence <400> 2097 gttgatggta ttgatgaatg gttatactat gaccgttttg aacgtgacta tgttaatgag 60 ggaattgaat atagtttgaa agataaacat ggtgctacct tgagtgtcgc taggttatat 120 aaagatacaa cagtgattaa aattactgat t 151 <210> 2098 <211> 151 <212> DNA <213> Artificial Sequence <400> 2098 ggttgaacca gaagaaaata aagctaaatc tgtggacgcg gaacgtgcta aagcattaga 60 ggaagacgtg gacaaattag aaaaaggaga ggctagaagt atggaaaatg taaagaaaat 120 caaccctcca gaaaacgttg ctgaagctga g 151 <210> 2099 <211> 151 <212> DNA <213> Artificial Sequence <400> 2099 aggggtcaat atggtcagaa ccagtgtttg gttgatgtgc cgttgcatat gcgtgagaaa 60 tgacacctgt attcccttgg tctagcgtct taggtagtcc cgcttcatca cataatagac 120 gaattaagtc tactagtagc ttatagtctt t 151 <210> 2100 <211> 151 <212> DNA <213> Artificial Sequence <400> 2100 tatcacctta aacaaacact aaagtagggg aggaatttaa atgaacacat atacagttta 60 ttaccgtaac attgatgagc actattgctg tagtattcac gttgacgcat atactattga 120 acaagctctt aataaagggt tacagtacct t 151 <210> 2101 <211> 150 <212> DNA <213> Artificial Sequence <400> 2101 agaagatata ttggaaaaag gtaaacgata taccattgtt ggagtaggca gccttttcgt 60 gcaggttgat ggtattgatg aatggttcta ctatgaccgt tttgaacgtg actatgttaa 120 tgagggaatt gaatatagtt tgaaagataa 150 <210> 2102 <211> 150 <212> DNA <213> Artificial Sequence <400> 2102 tttgaacgtg actatgttaa tgagggaatt gaatatagtt tgaaagataa acatggtgct 60 accttgagtg tcgctaggtt atataaagat aaaacagtga ttaaaattac tgattttacg 120 aatgatgtag taagcgtaca cttaacagac 150 <210> 2103 <211> 150 <212> DNA <213> Artificial Sequence <400> 2103 gtctgttaag tgtacgctta ctacatcatt cgtaaaatca gtaattttaa tcactgtttt 60 atctttatat aacctagcga cactcaaggt agcaccatgt ttatcttaca aactatattc 120 aagtccctca ataacatagt cacgttcaaa 150 <210> 2104 <211> 150 <212> DNA <213> Artificial Sequence <400> 2104 acttttgtaa actcacgaac ctttttagat ttctttctaa cagcctgtag ttgtgtctta 60 atcatgcgga aacaaataga cgcttggtct tttgtattgg ctgtagaata tatttgacgg 120 gacgccagtg gcgaacgttc gtaaagaagt 150 <210> 2105 <211> 150 <212> DNA <213> Artificial Sequence <400> 2105 taaaggcgcc tgatggtttc ccattttcgt caagataacc gtattcagat acctcttgag 60 ttgcctgact gtaaatagcg taagtattac aataaatgac tagcatgcca gcgtctagtt 120 ttgaaattgg tagctgttta agttgtggaa 150 <210> 2106 <211> 150 <212> DNA <213> Artificial Sequence <400> 2106 agagttggga tggttgtact ccctcctgat gtaggttcat caacgcttga ggtattgatt 60 gcccactctg ttttagttga tttgacagag gcgccatttt gtcccgttgt tctcatccac 120 gtgtacttac ttgggtccgt gctaggttct 150 <210> 2107 <211> 150 <212> DNA <213> Artificial Sequence <400> 2107 gtgaagccaa tttaccttta tcaagggtgt catacgttac agcacgtgtg aacaaacctc 60 ctgttgttga taagagtctg gaccatttag gagcttcttg cgtgtcaatc ataaccccat 120 tctcaagatt aaaacgccca tctgggtcaa 150 <210> 2108 <211> 150 <212> DNA <213> Artificial Sequence <400> 2108 tttgaattaa cagtaatgag tatttggaaa cgtgaaaaag gtagatgatt atatgacacc 60 tgttattaat gaaagcaatg agacccgtac cattaccatc tgcatggtca acggacgctc 120 ttacacagat aagggttccc cagagtttgt 150 <210> 2109 <211> 150 <212> DNA <213> Artificial Sequence <400> 2109 ggaacaagaa acctgagcca agttttccct catacatacg gtgtaagcca atgcctccaa 60 acaacaaagc aataataaca tatagtccta aacttggttt attcattcta gtagtcctcc 120 attaatgatt gtatgaaatc gtttaactcg 150 <210> 2110 <211> 150 <212> DNA <213> Artificial Sequence <400> 2110 tataccattt atgtgtaaaa cgttgttata ctagctcata cgcaacatca aggttaccta 60 aatcattttt agcaatctta acaataacaa actcatcctc aacttcatcc tgttccccat 120 ccacgcgaat agtcactttc ttttctattt 150 <210> 2111 <211> 150 <212> DNA <213> Artificial Sequence <400> 2111 ggaacaagaa acctgagcca agatttccct catacatacg gtgtaagcca atgcctccaa 60 acaacaaagc aataataaca tatagtccta aacttggttt attcattcta gtagtcctcc 120 attaatgttt gtatgaaatc gtttaactcg 150 <210> 2112 <211> 150 <212> DNA <213> Artificial Sequence <400> 2112 acttctttac gaacgttcgc caatggcgtc ccgtcaaata tattctacag ccaatacaaa 60 agaccaagcg tctatttgtt tccgcatgat taagacacaa ctacaggctg ttagaaagaa 120 atctaaacag gttcgtgagt ttacaaaagt 150 <210> 2113 <211> 150 <212> DNA <213> Artificial Sequence <400> 2113 tttgaattaa cagtaatgag tagttggaaa cgtgaaaaag gtagatgatt atatgacacc 60 tgttattaat gaaagcaatg agacccgtac cattaccatc tgcatggtca acggacgctc 120 ttacacatat aagggttccc cagagtttgt 150 <210> 2114 <211> 150 <212> DNA <213> Artificial Sequence <400> 2114 ggagtacaac catcccaact ctcgaaaaag gtaaatacct atggacacgt acaacgtggg 60 agtacactga tggtacaaca tcagtagcct atacagtgaa ctatattcct gtagatggct 120 caaccggtaa tggtgtgaaa tctatcgctg 150 <210> 2115 <211> 150 <212> DNA <213> Artificial Sequence <400> 2115 ggtgcattgt aggtaaatgg gttttttgta actggtttaa ttccgttgtt tgattggata 60 tgctcaaagt tccaagtgaa cttcttaccc gtttggtcac gtgtcattgt acagcggaac 120 caagatgttt tgtacttagt tacgtctgtc 150 <210> 2116 <211> 150 <212> DNA <213> Artificial Sequence <400> 2116 gcgtttgttt gattatgcaa aaacctatat gaaagagtat cataatgtag agttgcatta 60 tgatactaag tcagaagata tttttgttat aagaaatgat atgttcctat gggaataatg 120 tctaatatgg aggaaaaata aatgattact 150 <210> 2117 <211> 150 <212> DNA <213> Artificial Sequence <400> 2117 ttgacccaga tgggcgtttt aatcttgaga atggggttat gattgacacg caagaagctc 60 ctaaatggtc cagactctta tcaacaacag gaggtttgtt cacacgtgct gtaacgtatg 120 acaccctgga taaaggtaaa ttggcttcac 150 <210> 2118 <211> 150 <212> DNA <213> Artificial Sequence <400> 2118 tttgaattaa cagtaatgag tagttggaaa cgtgaaaaag gtagatgatt atatgacacc 60 tgttattaat gaaagcaatg agacccgtac cattaccatc tgcatggtca acggacgctc 120 ttacacagat aagggttccc cagagtttgt 150 <210> 2119 <211> 150 <212> DNA <213> Artificial Sequence <400> 2119 gcgtttgttt gattatgcaa aatcctatat gaaagagtat cataatgtag agttgcatta 60 tgatactaag tcagaagata tttttgttat aagaaatgat atgttcctat gggaataatg 120 tctaatatgg aggaaaaata aatgattact 150 <210> 2120 <211> 150 <212> DNA <213> Artificial Sequence <400> 2120 ggaacaagaa acctgagcca agatttccct catacatacg gtgtaagcca atgcctccaa 60 acaacaaagc aataataaca tatagtccta aacttggttt attcattcta gtagtcctcc 120 attaatgatt gtatgaaatc gtttaactcg 150 <210> 2121 <211> 150 <212> DNA <213> Artificial Sequence <400> 2121 acttctttac gaacgttcgc cactggcgtc ccgtcaaata tattctacag ccaatacaaa 60 agaccaagcg tctatttgtt tccgcatgat taagacacaa ctacaggctg ttagaaagaa 120 atctaaacag gttcgtgagt ttacaaaagt 150 <210> 2122 <211> 149 <212> DNA <213> Artificial Sequence <400> 2122 cattatggat gtctcacaaa attaaccctt gcataagcga gggttttatt atatactagt 60 gaacgagggg gatgaaatta atgaacacta ttttcacacc aactaagcaa caaaaagaga 120 acgcgcgtac catgtttgaa ctttggaaa 149 <210> 2123 <211> 149 <212> DNA <213> Artificial Sequence <400> 2123 tcttctcgca cgtagtaggt aacgggcgag taattcaaac agcacgcaca aacgcgggct 60 tttatgacgt aggtggcgga tggaactcgt ggggatatgc ggcaattgaa ttgattgaat 120 cgcacaatac caaagaagag tttatgaaa 149 <210> 2124 <211> 149 <212> DNA <213> Artificial Sequence <400> 2124 ttgcatacgt tcaataacaa actctgggga acccttatat gtgtaagagc gtccgttgac 60 catgcagatg gtaatggtac gggtctcatt gctttcatta ataacaggtg tcatataatc 120 atctaccatt ttcacgtttc caaatactc 149 <210> 2125 <211> 149 <212> DNA <213> Artificial Sequence <400> 2125 cgtgtaaaat caggtttcca agtcattaag taagaaacag cctccctacc tgtgcgtgtc 60 tcacggagtt tcaggcgtct cattgggtta ccttttttag attgtgtttc aatgttctct 120 gtaacaacaa cctcttttat tccccctgt 149 <210> 2126 <211> 149 <212> DNA <213> Artificial Sequence <400> 2126 gaaaatgcag taaaatacac gtatgaacca tcaaagtctt tgtagcgtac tacgtactta 60 tacataatca taacctcttt ctttgcagta ttgtataaac tccttatcat gtctttcgtc 120 tagcccagtc tgcgccttga ggttctcat 149 <210> 2127 <211> 149 <212> DNA <213> Artificial Sequence <400> 2127 cgcgcgtact atcatagtag gtaacacgca caattaattc tgttgttgct agactaccag 60 tccacccctt agagatgaat acactccctg atacagtgta cgttgtaccg cgcaaagcac 120 tgtagccctt tgataggtat gcaggacgt 149 <210> 2128 <211> 149 <212> DNA <213> Artificial Sequence <400> 2128 atgggttaat tagggtaggt aattttgacg ctctcagtac atggcaaaca ataaaacaag 60 gtgacacacc ttcaacgtat aaatttgagg gtataaccgc aggggcaact aatgctttta 120 gtatacatgg taattcaaat gctttaatt 149 <210> 2129 <211> 149 <212> DNA <213> Artificial Sequence <400> 2129 ttttcacgtt tccaaatact ccttactgtt aattcaaact cactctcgtc aagaggttca 60 ctgaaacagg ttgtcatgta caatttacac gcccatttat acaggtctaa gttgttcgtt 120 cccagtgcta acattcctgc tgtctgagc 149 <210> 2130 <211> 149 <212> DNA <213> Artificial Sequence <400> 2130 ttatgatacg tataataatg gttcctatag acatttgtca gttcgccaaa atacagagtt 60 cgccactaaa tacttgtcag agggtggtac gagtattcat ttacaccaga gtggtagtta 120 ttactcagat gagaacctca aggcgcaga 149 <210> 2131 <211> 149 <212> DNA <213> Artificial Sequence <400> 2131 tatctcacgt gttcccgcca aggggttgtg tgtgaagtcc atgatagtaa gacaggcact 60 atctccgtta tgtcgtctat aaattagata attacccaac tgcgccattt ctttaacttt 120 aactaactgc tcttgtgatt catcaaaat 149 <210> 2132 <211> 149 <212> DNA <213> Artificial Sequence <400> 2132 gatgtattag gataaaggga ggaaaacaaa atgagtaaag tatttgagga taattttact 60 aaacccctac cagtggggac gaaggtgcgc ttgattaaac ctgaaccaac tgaatttttt 120 atgaatgtgg gttacgagcg tgacaggga 149 <210> 2133 <211> 149 <212> DNA <213> Artificial Sequence <400> 2133 tttcataaac tcttctttgg ttttgtgcga ttcaatcaat tcaattgccg catatcccca 60 cgagttccat ccgccaccta cgtcataaaa gcccgcgttt gtgcgtgctg tttgaattac 120 tcgcccggta cctactacgt gcgagaaga 149 <210> 2134 <211> 149 <212> DNA <213> Artificial Sequence <400> 2134 agtctaatac ctcaatttgg ttatcatata cccaccatag gtgaccatca atacttagtt 60 caagttggtg cgtttgtccg tcaatttctt cagcgctatg agctactctg aacacctctc 120 caacgtagtc cctgtcacgc tcgtaaccc 149 <210> 2135 <211> 149 <212> DNA <213> Artificial Sequence <400> 2135 gttcggtgaa aactctaaag aagttgagga ggctagaatc tccctatcta aattagagtc 60 acaggctaaa ttatcaagta aagctcttaa atcaatggag aacgctagtg atggacttag 120 tgacatccaa ggtggagcag acgaggcta 149 <210> 2136 <211> 149 <212> DNA <213> Artificial Sequence <400> 2136 aatttagtat tgaattatga tgtctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctattatag caatgactt 149 <210> 2137 <211> 149 <212> DNA <213> Artificial Sequence <400> 2137 tagcctcgtc tgctccacct ttgatgtcac taagtccatc actagcgttc tccattgatt 60 taagagcttt acttgataat ttagcctgtg actctaattt agatagggag attctagcct 120 cctcaacgtc tttagagttt tcaccgaac 149 <210> 2138 <211> 149 <212> DNA <213> Artificial Sequence <400> 2138 aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa cactcgcatg 60 ttcccgtttg aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct 120 ttcgagacat cataattcaa tactaaatt 149 <210> 2139 <211> 149 <212> DNA <213> Artificial Sequence <400> 2139 actgcgccaa atatcctatt aaacggttca caggacaata gtatacagta ttggggaatc 60 tttgacgcag taacggctac accaacagca ggagccacta aattaactaa aacagcagtg 120 tcaacaagac gtcctgcata cctatcaaa 149 <210> 2140 <211> 149 <212> DNA <213> Artificial Sequence <400> 2140 tttgcgccca atgtaaagcc cgtgtctctc atgacaatgt tccagtagta ttgaaacgat 60 tgaggtgacg tggttttaat agcaggtaca acattattaa gtaagtcaag tgcaccatct 120 tcacaacgta tctcacgtgt tcccgccaa 149 <210> 2141 <211> 149 <212> DNA <213> Artificial Sequence <400> 2141 tttcataaac tcttctttgg tattgtgcga ttcaatcaat tcaattgccg catatcccca 60 cgagttccat ccgccaccta cgtcataaaa gcccgcgttt gtgcgtgctg tttgaattac 120 tcgcccggta cctactacgt gcgagaaga 149 <210> 2142 <211> 149 <212> DNA <213> Artificial Sequence <400> 2142 tagcctcgtc tgctccacct tggatgtcac taagtccatc actagcgttc tccattgatt 60 taagagcttt acttgataat ttagcctgtg actctaattt agatagggag attctagcct 120 cctcaacgtc tttagagttt tcaccgaac 149 <210> 2143 <211> 148 <212> DNA <213> Artificial Sequence <400> 2143 aggctgtaaa ggaaacggga attgtacaca aagccaaaat gtacgtgcgt ttgaaaattt 60 tcccaatgga tggctctaac gcgcgcgtaa acgaaccact cctacatttc tttctcagtt 120 tttatgatta tgcagacacc tcaacatg 148 <210> 2144 <211> 148 <212> DNA <213> Artificial Sequence <400> 2144 aatgggaaac acataatcta aatcatagtg aggttggctc tggcaagaca ctcatggcat 60 tagaatcgtt taaaaaatca gggctaaaga aactcgtagt agtgtgcctt gcgtctaagg 120 tgtctgattg ggcttctgag gggtctaa 148 <210> 2145 <211> 148 <212> DNA <213> Artificial Sequence <400> 2145 gaacctcagc ttcagcaacg ttttctgtag ggttgatttt ctttacattt tccatacttc 60 tagcctctcc tttttctaat ttgtccacgt cttcctctaa tgctttagca cgttccgcgt 120 ccacagagtt atctttattt tcttctgg 148 <210> 2146 <211> 148 <212> DNA <213> Artificial Sequence <400> 2146 aacctcagct tcagcaacgt tttctgtagg gttgattttc tttacatttt ccatacttct 60 agcctctcct ttttctaatt tgtccacgtc ttcctctaat gctttagcac gttccgcgtc 120 cacagatgta tctttatttt cttctggt 148 <210> 2147 <211> 148 <212> DNA <213> Artificial Sequence <400> 2147 tactcaatgg ctttgactct catgccatgt tttttacctc ctctaataat ctacagaaca 60 ataatatgta tatacatttg attgtcctgc atttactgtg attgtttttc ctgttgctgt 120 ccatgatgtg tctaatacgt ttgaggcg 148 <210> 2148 <211> 148 <212> DNA <213> Artificial Sequence <400> 2148 gctttaaatg ggtttttact ttctttagat ttacctgttc ccatccatgt gaatcttgaa 60 tctgtcacct gcatttttgc aacaatagag taggtctctt tcttcttgtg ttccacacgt 120 ttagtgtgtt gtaggtaata tccactga 148 <210> 2149 <211> 148 <212> DNA <213> Artificial Sequence <400> 2149 ttgacagtca tgggaccatc tacagggtga ccgccacttg gtgtaccttt ggcgtattca 60 ggtgcctccc atgtttttaa cttgtccatg cctagttttt ctaaaaccca gtttgcaccg 120 ccaataagtc cgttcactgg tttttcaa 148 <210> 2150 <211> 148 <212> DNA <213> Artificial Sequence <400> 2150 gaacctcagc ttcagcaacg gtttctgtag ggttgatttt ctttacattt tccatacttc 60 tagcctctcc tttttctaat ttgtccacgt cttcctctaa tgctttagca cgttccgcgt 120 ccacagattt atctttattt tcttctgg 148 <210> 2151 <211> 148 <212> DNA <213> Artificial Sequence <400> 2151 ttgaaaaacc agtgaacgga attattggcg gtgcaaactg ggttttagaa aaactaggca 60 tggacaagtt aaaaacatgg gaggcacctg aatacgccaa aggtacacca agtggcggtc 120 accctgtcga tggtcccatg actgtcaa 148 <210> 2152 <211> 148 <212> DNA <213> Artificial Sequence <400> 2152 tttcgagaaa tcataattca atactaaatt atcatttggg tattggagtg tgaacctctc 60 ttttccatca ctactccatg cgtaagctgt gtgtaaaaat ggattttgac catcctgtac 120 gtttgcacta ctcaatggct ttgactct 148 <210> 2153 <211> 148 <212> DNA <213> Artificial Sequence <400> 2153 ctacgcaaag aggttgctta gtgttggaaa gacgtagacg ccactgagct acgcttctat 60 ggttgtgttg atgggttact tgctaaagcg tttatttgtg ccatgttcaa ccttgataaa 120 caagcattta accaaacaaa cgctaatt 148 <210> 2154 <211> 148 <212> DNA <213> Artificial Sequence <400> 2154 caggggtatt gtgaaatttc ttcccgtcct gacggtcagt gtgattggga ggatatgtta 60 aattgggatt tggcgtttat tgagacaaac aatttagacg tacaaggtat ttgttatgac 120 cctgcacagt ctcaattaat taccacaa 148 <210> 2155 <211> 148 <212> DNA <213> Artificial Sequence <400> 2155 aatttagtat tgaattatga gttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctattatag caatgact 148 <210> 2156 <211> 148 <212> DNA <213> Artificial Sequence <400> 2156 aatttagtat tgaattatga gttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctattatag caatgact 148 <210> 2157 <211> 148 <212> DNA <213> Artificial Sequence <400> 2157 cggtggtatg gacacagttg tcaattggat aaaaggactg cctaagaaac taggggacgg 60 aattaaagga ggcgctcact tcctaaaaga cgcattcaaa ggtatgttta acggagcctt 120 gaaagtactt gaaaaaccag tgaacgga 148 <210> 2158 <211> 148 <212> DNA <213> Artificial Sequence <400> 2158 aacctcagct tcagcaacgt gttctgtagg gttgattttc tttacatttt ccatacttct 60 agcctctcct ttttctaatt tgtccacgtc ttcctctaat gctttagcac gttccgcgtc 120 cacagattta tctttatttt cttctggt 148 <210> 2159 <211> 148 <212> DNA <213> Artificial Sequence <400> 2159 gctttaaatg ggtttttact gtctttagat ttacctgttc ccatccatgt gaatcttgaa 60 tctgtcacct gcatttttgc aacaatagag taggtctctt tcttcttgtg ttccacacgt 120 ttagtgtttt gtaggtaata tccactga 148 <210> 2160 <211> 148 <212> DNA <213> Artificial Sequence <400> 2160 gaacctcagc ttcagcaacg gtttctgtag ggttgatttt ctttacattt tccatacttc 60 tagcctctcc tttttctaat ttgtccacgt cttcctctaa tgctttagca cgttccgcgt 120 ccacagagtt atctttattt tcttctgg 148 <210> 2161 <211> 148 <212> DNA <213> Artificial Sequence <400> 2161 tcagtggata ttacctacaa cacactaaac gtgtggaaca caagaagaaa gagacctact 60 ctattgttgc aaaaatgcag gtgacagatt caagattcac atggatggga acaggtaaat 120 ctaaagacag taaaaaccca tttaaagc 148 <210> 2162 <211> 148 <212> DNA <213> Artificial Sequence <400> 2162 ttgacagtca tgggaccatc gacagggtga ccgccacttg gtgtaccttt ggcgtattca 60 ggtgcctccc atgtttttaa cttgtccatg cctagttttt ctaaaaccca gtttgcaccg 120 ccaataagtc cgttcactgg tttttcaa 148 <210> 2163 <211> 148 <212> DNA <213> Artificial Sequence <400> 2163 aacctcagct tcagcaacgt gttctgtagg gttgattttc tttacatttt ccatacttct 60 agcctctcct ttttctaatt tgtccacgtc ttcctctaat gctttagcac gttccgcgtc 120 cacagatgta tctttatttt cttctggt 148 <210> 2164 <211> 147 <212> DNA <213> Artificial Sequence <400> 2164 atcaatcata attaaatcga ttgactcttt tgtaaatgcg ttgtacacgg ctcttgtcaa 60 tagagggttg ttaaagtgaa ggaccttgcc cgctcgtata tccacttgta attgtttagt 120 aggtgggttt aatcgcatat aagactg 147 <210> 2165 <211> 147 <212> DNA <213> Artificial Sequence <400> 2165 acttggctca ggtttcttgg tcctattctt attttggacg ggtgtaccag tggttatttc 60 atggattgac attattacag cactaacaac gcgcagacac ttattttcat aggaggaata 120 gtatgggacg tcaatacaaa aagggtg 147 <210> 2166 <211> 147 <212> DNA <213> Artificial Sequence <400> 2166 atcatagtga ggttggctct ggcaagacac tcatggcatt agaatcgttt aaaaaatcag 60 ggctaaagaa actcgtagta gtgtgccttg cgtctaaggt gtctgattgg gcttctgagg 120 ggtctaaaca aggtttaggt ataatta 147 <210> 2167 <211> 147 <212> DNA <213> Artificial Sequence <400> 2167 taatgttaat accaacggaa caacagcaaa tggtcataga caaatgggaa acacataatc 60 taaatcatag tgaggttggc tcaggcaaga cactcatggc attagaatcg tttaaaaaat 120 cagggctcaa gaaactcgta gtagtgt 147 <210> 2168 <211> 147 <212> DNA <213> Artificial Sequence <400> 2168 taattatacc taaaccttga ttagacccct cagaagccca atcagacacc ttagacgcaa 60 ggcacactac tacgagtttc tttagccctg attttttaaa cgattctaat gccatgagtg 120 tcttgcctga gccaacctca ctatgat 147 <210> 2169 <211> 147 <212> DNA <213> Artificial Sequence <400> 2169 tggggacgaa aaggaaccca cgttttaaca gcagaagaaa ctgcacaagt gttaggtcat 60 aaacgtccta agtttgcata caaaaaaggt actggcttct ttgacaaaat tacaggaggc 120 gtaaaaatca tctggaacgg tgccaaa 147 <210> 2170 <211> 147 <212> DNA <213> Artificial Sequence <400> 2170 aagttctgac accctaatac agatggcgtc tctcagtccc aaattaaatg ccacagtttc 60 ttctagtaaa atattcatgg tgacctctcc tctttacccc tcatgtctct cattaacaac 120 ataatcaaag tcacttgcaa atagcgg 147 <210> 2171 <211> 147 <212> DNA <213> Artificial Sequence <400> 2171 taatgttaat accaacggac caacagcaaa tggtcataga caaatgggaa acacataatc 60 taaatcatag tgaggttggc tcaggcaaga cactcatggc attagaatcg tttaaaaaat 120 cagggctaaa gaaactcgta gtagtgt 147 <210> 2172 <211> 147 <212> DNA <213> Artificial Sequence <400> 2172 gactcatcaa ctaacagaag agtctattat agcaatgact tattaaccaa ctacttgcca 60 gcaggagtta aatattccgt cacaatagac gcattcagca acaataatgg gttaattagg 120 gtaggtactt ttgacgctct cagtaca 147 <210> 2173 <211> 147 <212> DNA <213> Artificial Sequence <400> 2173 taagttatct tctgtaggta tagttttctt agtcatattt acaagtttca taagcagtta 60 cctcctataa ttcctctcta gccttttcaa taaactcgtc tatactaaca taaccaagtt 120 ttagaaggtg tgccacctgt agcattg 147 <210> 2174 <211> 147 <212> DNA <213> Artificial Sequence <400> 2174 ttacttatga tatgttagtt gataacgtag cctttgagga cttattacca ttagtacagg 60 gagtctttga acaagtcaac gggggtacag tttcaaagga gaaataacag gacttgagga 120 aaaaaccttt gaggaacagt tagaaac 147 <210> 2175 <211> 147 <212> DNA <213> Artificial Sequence <400> 2175 ctacagccct tctgaggcgt ttaaacctaa gtgggctaca acattcgcac caaacgcatg 60 gtcaggacct tcccttacaa cgcctgtcaa agcaccatca acaggtttac gaacaggagc 120 ctttaaaatt gaggaacgga tagactt 147 <210> 2176 <211> 147 <212> DNA <213> Artificial Sequence <400> 2176 taagttatct tctgtaggtc tagttttctt agtcatattt acaagtttca taagcagtta 60 cctcctataa ttcctctcta gccttttcaa taaactcgtc tatactaaca taaccaagtt 120 ttagaagttg tgccacctgt agcattg 147 <210> 2177 <211> 147 <212> DNA <213> Artificial Sequence <400> 2177 ttacttatga tatgttagtg gataacgtag cctttgagga cttattacca ttagtacagg 60 gagtctttga acaagtcaac gggggtacag tttcaaagga gaaataacag gacttgagga 120 aaaaaccatt gaggaacagt tagaaac 147 <210> 2178 <211> 147 <212> DNA <213> Artificial Sequence <400> 2178 caagaaacct gagccaagtg ttccctcata catacggtgt aagccaatgc ctccaaacaa 60 caaagcaata ataacatata gtcctaaact tggtttattc attctagtag tcctccatta 120 atgtttgtat gaaatcgttt aactcgt 147 <210> 2179 <211> 147 <212> DNA <213> Artificial Sequence <400> 2179 tttggcaccg ttccagatgt tttttacgcc tcctgtaatt ttgtcaaaga agccagtacc 60 ttttttgtat gcaaacttag gacgtttatg acctaacact tgtgcagttt cttctgctgt 120 taaaacgagg gttccttttc gtcccca 147 <210> 2180 <211> 147 <212> DNA <213> Artificial Sequence <400> 2180 tgtactgaga gcgtcaaaag tacctaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg atgagtc 147 <210> 2181 <211> 147 <212> DNA <213> Artificial Sequence <400> 2181 ttacttatga tatgttagtt gataacgtag cctttgagga cttattacca ttagtacagg 60 gagtctttga acaagtcaac gggggtacag tttcaaagga gaaataacag gacttgagga 120 aaaaaccatt gaggaacagt tagaaac 147 <210> 2182 <211> 147 <212> DNA <213> Artificial Sequence <400> 2182 taattatacc taaaccttga ttagacccct cagaagccca atcagacacc ttagacgcaa 60 ggcacactac tacgagtttc tttagccctg attttttaaa cgattctaat gccatgagtg 120 tcttgccaga gccaacctca ctatgat 147 <210> 2183 <211> 147 <212> DNA <213> Artificial Sequence <400> 2183 tttggcaccg ttccagatga tttttacgcc tcctgtaatt ttgtcaaaga agccagtacc 60 ttttttgtat gcaaacttag gacgtttatg acctaacact tgtgcagttt cttctgctgt 120 taaaacgagg gttccttttc gtcccca 147 <210> 2184 <211> 147 <212> DNA <213> Artificial Sequence <400> 2184 taatgttaat accaacggac caacagcaaa tggtcataga caaatgggaa acacataatc 60 taaatcatag tgaggttggc tcaggcaaga cactcatggc attagaatcg tttaaaaaat 120 cagggctcaa gaaactcgta gtagtgt 147 <210> 2185 <211> 147 <212> DNA <213> Artificial Sequence <400> 2185 taagttatct tctgtaggtc tagttttctt agtcatattt acaagtttca taagcagtta 60 cctcctataa ttcctctcta gccttttcaa taaactcgtc tatactaaca taaccaagtt 120 ttagaaggtg tgccacctgt agcattg 147 <210> 2186 <211> 147 <212> DNA <213> Artificial Sequence <400> 2186 ccgctatttg caagtgactg tgattatgtt gttaatgaga gacatgaggg gtaaagagga 60 gaggtcacca tgaatatttt actagaagaa actgtggcat ttaatttggg actgagagac 120 gccatctgta ttagggtgtc agaactt 147 <210> 2187 <211> 147 <212> DNA <213> Artificial Sequence <400> 2187 ctacagccct tctgaggcga ttaaacctaa gtgggctaca acattcgcac caaacgcatg 60 gtcaggacct tcccttacaa cgcctgtcaa agcaccatca acaggtttac gaacaggagc 120 ctttaaaatt gaggaacgga tagactt 147 <210> 2188 <211> 146 <212> DNA <213> Artificial Sequence <400> 2188 tggtattgat gaatggttct actatgaccg ttttgaacgt gactatgtta atgagggaat 60 tgaatatagt ttgaaagata aacatggtgc taccttgagt gtcgctaggt tatataaaga 120 taaaacagtg attaaaatta ctgatt 146 <210> 2189 <211> 146 <212> DNA <213> Artificial Sequence <400> 2189 tctaggctcc cgctctcaaa cgcctcagta acacgtgacg taagagcgct agtagctttc 60 ttaatcattc cacgggcaac gtctagagga tattttatga gacctgaggt gtctactacg 120 ctagagacta ctttttcaac taattt 146 <210> 2190 <211> 146 <212> DNA <213> Artificial Sequence <400> 2190 ttctgatggt actacctaca atctcaaccc cactaacttt tttaaacatc ccgttttcag 60 caataacatt gtctgataca atattattaa ttgacatccc ccagttttcc cacgctgtac 120 cgttccagtt tagcacagta gggtca 146 <210> 2191 <211> 146 <212> DNA <213> Artificial Sequence <400> 2191 atctgtttgc tagaagaaga ccgtccgtga agagtttcaa ttcaacaagg tcaccctcat 60 tacccgtgtg ctcaaatagt ccactattaa aggctaaatc aataacaggt gttttactac 120 gtactagttc ctcacgcatt tcctta 146 <210> 2192 <211> 146 <212> DNA <213> Artificial Sequence <400> 2192 taatcgttgc gcctctaggt cctgttcatt atctagagca tgaccaattt tacagagcag 60 tgtgtggcgc attagttcta attctttacg cagtggtcta ttcattgtct cactggcgtc 120 aaacatatta gaggcatgaa ataaat 146 <210> 2193 <211> 146 <212> DNA <213> Artificial Sequence <400> 2193 acgtactttc tgcctaaaca acagtacact catataggcg tcattatatt ctgttaatct 60 aacatgttca accttaaaca ttaaaatacc tcctcaggtt gtaagtaaac gtcaaaaacc 120 tcctccactc agcttaccac cgcaca 146 <210> 2194 <211> 146 <212> DNA <213> Artificial Sequence <400> 2194 gtgccatccg ttttgacgta gtagctacag acacaaaggc gggcttaatg ttcaaattag 60 gagctattcc taacaacgtt tctacggtaa cagtagcaaa tgcgtctgag ttccctagtg 120 gtggagctgg agcctaataa ctaacc 146 <210> 2195 <211> 146 <212> DNA <213> Artificial Sequence <400> 2195 tcagcttacc accgcacagt gggcaatagt gaatctcaaa ctgagcggta taaccttggt 60 tgtcaacctc agttgtgact gtcatagttt tcccgtttat aaacacctca gtcatgtcag 120 tcctcccact ccataagtaa tctgag 146 <210> 2196 <211> 146 <212> DNA <213> Artificial Sequence <400> 2196 tagtgattta acttgggtat tccctacaga cattaatgat aaacgttacg cttcattttt 60 cgcaagtgat ttcacttata aggagagtga acctaatgtc caatagatgg gaaacgcctg 120 agaacctgga taaagaggat aaagtt 146 <210> 2197 <211> 146 <212> DNA <213> Artificial Sequence <400> 2197 tttagcacag tagggtcagt aggtttttgc cataatgtcc ctgtagttgg gttacttgga 60 gctgtagcac taataaaaat tgagtctcta cccgtgtatg agctagttac tacccaattt 120 gtatacgtac catttgaaag cgtatt 146 <210> 2198 <211> 146 <212> DNA <213> Artificial Sequence <400> 2198 aaattagttg aaaaagtatt ctctagcgta gtagacacct caggtctcat aaaatatcct 60 ctagacgttg cccgtggaat gattaagaaa gctactagcg ctcttacgtc acgtgttact 120 gaggcgtgtg agagcgggag cctaga 146 <210> 2199 <211> 146 <212> DNA <213> Artificial Sequence <400> 2199 taatcgttgc gcctctagtt cctgttcatt atctagagca tgaccaattt tacagagcag 60 tgtgtggcgc attagttcta attctttacg cagtggtcta ttcattgtct cactggcgtc 120 aaacataata gaggcatgaa ataaat 146 <210> 2200 <211> 146 <212> DNA <213> Artificial Sequence <400> 2200 gtgccatccg ttttgacgga gtagctacag acacaaaggc gggcttaatg ttcaaattag 60 gagctattcc taacaacgtt tctacggtaa cagtagcaaa tgcgtctgag ttccctagtg 120 gtggagcagg agcctaataa ctaacc 146 <210> 2201 <211> 146 <212> DNA <213> Artificial Sequence <400> 2201 actggaaccg gttggcgagt atattaaaac catcacggag ttattatgga atatgggcgc 60 catcatgttt gaaaaggttt atccattatt aaaacccata ctagacacga tttttagtgc 120 gttcggtagc attttcaaac aggtaa 146 <210> 2202 <211> 146 <212> DNA <213> Artificial Sequence <400> 2202 tgacggtgta tagaccatga gggtgttagg tatggtttca tgtcctaagt ctttcattaa 60 ggtagtaaaa gagtgtattc cgtttgcttt accttttacg tcacagtcta ctactaataa 120 tttgttttgt tccccacata agaccc 146 <210> 2203 <211> 146 <212> DNA <213> Artificial Sequence <400> 2203 tcatacaacg caaacacaga cacatatcac cgcacaattg accaaattgg tagattggta 60 gagatttcac tagtttcaat tcccgcatat gatgatacaa ctgtagcagt ggcacaacgg 120 tcacaaacag cgtttaaaga acaaaa 146 <210> 2204 <211> 146 <212> DNA <213> Artificial Sequence <400> 2204 ttacctgttt gaaaatgcga ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 60 atggataaac cttttcaaac atgatggcgc ccatattcca taataactcc gtgatggttt 120 taatataatc gccaaccggt tccagt 146 <210> 2205 <211> 146 <212> DNA <213> Artificial Sequence <400> 2205 ttttgttctt taaacgcttt ttgtgaccgt tgtgccactg ctacagttgt atcatcatat 60 gcgggaattg aaactagtga aatctctacc aatctaccaa tttggtcaat tgtgcggtga 120 tatgtgtatg tgtttgcgtt gtatga 146 <210> 2206 <211> 146 <212> DNA <213> Artificial Sequence <400> 2206 taaggaaatg cgtgaggacc tagtacgtag taaaacacct gttattgatt tagcctttaa 60 tagtggacta tttgagcaca cgggtaatga gggtgacctt gttgaattga aactcttcac 120 ggacggtctt cttctagcaa acagat 146 <210> 2207 <211> 146 <212> DNA <213> Artificial Sequence <400> 2207 gtgccatccg ttttgacgga gtagctacag acacaaaggc gggcttaatg ttcaaattag 60 gagctattcc taacaacgtt tctacggtaa cagtagcaaa tgcgtctgag ttccctagtg 120 gtggagctgg agcctaataa ctaacc 146 <210> 2208 <211> 146 <212> DNA <213> Artificial Sequence <400> 2208 taatcgttgc gcctctaggt cctgttcatt atctagagca tgaccaattt tacagagcag 60 tgtgtggcgc attagttcta attctttacg cagtggtcta ttcattgtct cactggcgtc 120 aaacataata gaggcatgaa ataaat 146 <210> 2209 <211> 146 <212> DNA <213> Artificial Sequence <400> 2209 ttacctgttt gaaaatgcga ccgaacgcac taaaaatcgt gtctagtatg ggttttaata 60 atggataaac cttttcaaac atgatggcgc ccatattcca taataactcc gtgatggttt 120 taatatactc gccaaccggt tccagt 146 <210> 2210 <211> 146 <212> DNA <213> Artificial Sequence <400> 2210 ttttgttctt taaacgctgt ttgtgaccgt tgtgccactg ctacagttgt atcatcatat 60 gcgggaattg aaactagtga aatctctacc aatctaccaa tttggtcaat tgtgcggtga 120 tatgtgtatg tgtttgcgtt gtatga 146 <210> 2211 <211> 146 <212> DNA <213> Artificial Sequence <400> 2211 aaattagttg aaaaagtagt ctctagcgta gtagacacct caggtctcat aaaatatcct 60 ctagacgttg cccgtggaat gattaagaaa gctactagcg ctcttacgtc acgtgttact 120 gaggcgtgtg agagcgggag cctaga 146 <210> 2212 <211> 145 <212> DNA <213> Artificial Sequence <400> 2212 atagtctgcc tcgttttgcg ctgtagatga tgaattcccc gtactgtgta cgtgaatttg 60 tccatacggt cttaccccta cttgtggtaa acctgagcgc atttgttttt caattttcat 120 tgaatcagtc tcctttctat ctcta 145 <210> 2213 <211> 145 <212> DNA <213> Artificial Sequence <400> 2213 tctcctttct atctctactc attataacac aaaaaaggag gcttaagcct ccttaggtta 60 tgctaaacgc ccttgacgtc tgttagatac catttgtccg cgttgcttat ctttagttaa 120 agcagggttt agttccgcag taact 145 <210> 2214 <211> 145 <212> DNA <213> Artificial Sequence <400> 2214 aaattgaggt attagacgat gaggaggaaa aataatatga caaaattagc agaggtatta 60 gaattacatg acgcggagtt agacaatgtt ttagatgaat tgcgtgcccg cattatggac 120 gagcctaaag aattagacat tatga 145 <210> 2215 <211> 145 <212> DNA <213> Artificial Sequence <400> 2215 ttgattgccc actctgtttt agttgatttg acagaggcgc cagtttgtcc cgttgttctc 60 atccacgtgt acttacttgg gtccgtgcta ggttcttgag tatagttact atattgaccc 120 atatatagcg gatatgcgtt cgcga 145 <210> 2216 <211> 145 <212> DNA <213> Artificial Sequence <400> 2216 gtaccctata cgcaaccaac gaacctctat tctagctgta tatgcaaaca acggtttaga 60 cctaatggag gcagtacagc aatatgagaa agtacgcgcg gagggaatgc gtttacagga 120 gcaagaaata gaaaagaaag tgact 145 <210> 2217 <211> 145 <212> DNA <213> Artificial Sequence <400> 2217 tcataatgtc taattctata ggctcgtcca taatgcgggc acgcaattca tctaaaacat 60 tgtctaactc cgcgtcatgt aattctaata cctctgctaa ttttgtcata ttatttttcc 120 tcctcatagt ctaatacctc aattt 145 <210> 2218 <211> 145 <212> DNA <213> Artificial Sequence <400> 2218 agcttgtttg aattgttttg ttagtttgtc aagtgtatta cctagttcag cggttccgtc 60 aatacctaaa ccaatcttca tatttcctac tggttttccg ctttgcacca tgtgttaatc 120 agctcctttt ttctctagct tttca 145 <210> 2219 <211> 145 <212> DNA <213> Artificial Sequence <400> 2219 atatattcta cagccaaaac aaaagaccaa gcgtctattt gtttccgcat gattaagaca 60 caactacagg ctgttagaaa gaaatctaaa aaggttcgtg agtttacaaa agtaaacaaa 120 tatgacattg agacaaaaga tgact 145 <210> 2220 <211> 145 <212> DNA <213> Artificial Sequence <400> 2220 atatattcta cagccaaaac aaaagaccaa gcgtctattt gtttccgcat gattaagaca 60 caactacagg ctgttagaaa gaaatctaaa aaggttcgtg agtttacaaa agtaaacaaa 120 tatgacaatg agacaaaaga tgact 145 <210> 2221 <211> 145 <212> DNA <213> Artificial Sequence <400> 2221 aaattgaggt attagacgat gaggaggaaa aataatatga caaaattagc agaggtatta 60 gaattacatg acgcggagtt agacaatgtt ttagatgaat tgcgtgcccg cattatggac 120 gagcctatag aattagacat tatga 145 <210> 2222 <211> 145 <212> DNA <213> Artificial Sequence <400> 2222 atatattcta cagccaatac aaaagaccaa gcgtctattt gtttccgcat gattaagaca 60 caactacagg ctgttagaaa gaaatctaaa aaggttcgtg agtttacaaa agtaaacaaa 120 tatgacaatg agacaaaaga tgact 145 <210> 2223 <211> 144 <212> DNA <213> Artificial Sequence <400> 2223 cttctgaggc gtttaaacct aagtgggcta caacattcgc accaaacgca tggtcaggac 60 cttcccttac aacgcctgtc aaagcaccat caacaggttt acgaacagga gcctttaaat 120 ttgaggaccg gatagacttc ggta 144 <210> 2224 <211> 144 <212> DNA <213> Artificial Sequence <400> 2224 tatacagtga actatagtcc tgtagatggc tcaaccggta atggtgtgaa atctatcgct 60 gttacttacg ctgtaggtac ctcaggtaca acagcaccat ccacaggttg gcaagcaaca 120 ccaccaaatg taacaggtgg tcaa 144 <210> 2225 <211> 144 <212> DNA <213> Artificial Sequence <400> 2225 actagtagct tatagtcttt cataaactct tctttggtat tgtgcgattc aatcaattca 60 attgccgcat atccccacga gttccatccg ccacctacgt cataaaagcc cgcgtttgtg 120 cgtgctgttt gaattactcg cccg 144 <210> 2226 <211> 144 <212> DNA <213> Artificial Sequence <400> 2226 gcgaaaagca aaagtgacac ctgttattgt tacaggtaca gtagaaccgc ctgtaggtaa 60 ggaggagtta ctcattggac gtgaggcatt gcttgactta gaaacagata gcatttacat 120 tgaggctcgt gatttaactt gggt 144 <210> 2227 <211> 144 <212> DNA <213> Artificial Sequence <400> 2227 cgtctgttag ataccatttg tccgcgttgc ttatctttag ttaaagcagg gtttagttcc 60 gcagtaactt tacgtttgtc taagtagacg tccgtgtcct tttctagtaa tgcttgtaac 120 agtgcgtgtg tttgttgttg ctgt 144 <210> 2228 <211> 144 <212> DNA <213> Artificial Sequence <400> 2228 tatacagtga actatattcc tgtagatggc tcaaccggta atggtgtgaa atctatcgct 60 gttacttacg ctgtaggtac ctcaggtaca acagcaccat ccacaggttg gcaagcaaca 120 ccaccaactg taacaggtgg tcaa 144 <210> 2229 <211> 144 <212> DNA <213> Artificial Sequence <400> 2229 taccgaagtc tatccgttcc tcaaatttaa aggctcctgt tcgtaaacct gttgatggtg 60 ctttgacagg cgttgtaagg gaaggtcctg accatgcgtt tggtgcgaat gttgtagccc 120 acttaggatt aaacgcctca gaag 144 <210> 2230 <211> 144 <212> DNA <213> Artificial Sequence <400> 2230 ctaataaatg tattaataca ttaggaggaa aacagatgaa taaagaagaa acacacaaag 60 cgtttgagaa cgtcttacag gaactaaagt ttgattttga taagttgaaa tacggtaaaa 120 aagtagatga ggaaaaactt gctt 144 <210> 2231 <211> 144 <212> DNA <213> Artificial Sequence <400> 2231 cgttttaaat tgctctaaca taattatccc ccttagaata aatcttgacc cgcatatacg 60 caagagatgt ttatccatgc gcctgacgga atcgcactat ctactgtagt accataccta 120 cttactataa ttgcaccatc cttg 144 <210> 2232 <211> 144 <212> DNA <213> Artificial Sequence <400> 2232 cgtctgttag ataccagttg tccgcgttgc ttatctttag ttaaagcagg gtttagttcc 60 gcagtaactt tacgtttgtc taagtagacg tccgtgtcct tttctagtaa tgcttgtaac 120 agtgcgtttg tttgttgttg ctgt 144 <210> 2233 <211> 144 <212> DNA <213> Artificial Sequence <400> 2233 gcgtcatctg atacaatagt aacagagaca taaggagctt gagtgtcctg ccccactgtc 60 ataataccat tttcgtctgc ggtaatacct aaaacagcac tatatgctcc acccgcttgt 120 aagtcgaaaa cattcaatga tacg 144 <210> 2234 <211> 144 <212> DNA <213> Artificial Sequence <400> 2234 ttgagaaaga gaaacacaga gaccctatac catgtagaac gattgatggt atacgtcagc 60 tcattccgta cgaacattta caagaaattt aaaaataatg cttgacaact ggttggggtt 120 ttgataatct aataaatgta ttaa 144 <210> 2235 <211> 144 <212> DNA <213> Artificial Sequence <400> 2235 gtaagtaaat atgcgtgtct tgttgatggt attaactcat ggttcttagc acaagaccta 60 gacacggcgt catctaacat gggtaatagc tctaaaccgt caggagtcct taaatggaca 120 actgaaaatg ctaaggctac tact 144 <210> 2236 <211> 144 <212> DNA <213> Artificial Sequence <400> 2236 gcgtcatctg atacaaaagt aacagagaca taaggagctt gagtgtcctg ccccactgtc 60 ataataccat tttcgtctgc ggtaatacct aaaacagcac tatatgctcc acccgcttgt 120 aagtcgacaa cattcaatga tacg 144 <210> 2237 <211> 144 <212> DNA <213> Artificial Sequence <400> 2237 ttaatgtctg tggtatctta cccgtatctt ttagccttga cctttgtcaa cgcggtaatc 60 ttaattcctg tcccaactac gccacacctg agtgttagtg aactcgttct aaataaaacc 120 tctgtaatag agtaaagaga ccta 144 <210> 2238 <211> 144 <212> DNA <213> Artificial Sequence <400> 2238 gaggcacgtg agtatttaat gaacatgaac ctcaagacgg taccagtcac tgaggtagat 60 ggtaaattaa tattaggttt taatgtacct gaactaagac aattgattaa ataaaaaaga 120 gacctatcta ggtctcttta ctct 144 <210> 2239 <211> 144 <212> DNA <213> Artificial Sequence <400> 2239 agtagtagcc ttagcagttt cagttgtcca tttaaggact cctgacggtt tagagctatt 60 acccatgtta gatgacgccg tgtctaggtc ttgtgctaag aaccatgagt taataccatc 120 aacaagaaac gcatatttac ttac 144 <210> 2240 <211> 144 <212> DNA <213> Artificial Sequence <400> 2240 ccgtcatttc agtacgtttg aacaaagtaa tagcttgttc taagtcacca atgaataata 60 gtttatcatt tgtgtcgttt ttaaagatag cgtcaggaag tacaattacc tctttaccaa 120 acaatgtatt accacttgcc attg 144 <210> 2241 <211> 144 <212> DNA <213> Artificial Sequence <400> 2241 gtaggacttc cttagatttc attgtccatg ttaccttatc cactacctcc cttgtggcta 60 ctgagtcttt atacttgagt agccatctag atgttttaac aacggaagct ttgtttgcta 120 caggtgcctt gtaggtaaat gggt 144 <210> 2242 <211> 144 <212> DNA <213> Artificial Sequence <400> 2242 ttctgttagt tgatgattcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tgga 144 <210> 2243 <211> 144 <212> DNA <213> Artificial Sequence <400> 2243 attgctataa tagactattc tgttagttga tgagtcgtta aacaacactc gcatgttccc 60 gtttgaatat tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga 120 gaaatcagaa ttcaatacta aatt 144 <210> 2244 <211> 144 <212> DNA <213> Artificial Sequence <400> 2244 gtaggacttc cttagagttc attgtccatg ttaccttatc cactacctcc cttgtggcta 60 ctgagtcttt atacttgagt agccatctag atgttttaac aacggaagct ttgtttgcta 120 caggtgcatt gtaggtaaat gggt 144 <210> 2245 <211> 144 <212> DNA <213> Artificial Sequence <400> 2245 agtagtagcc ttagcagttt cagttgtcca tttaaggact cctgacggtt tagagctatt 60 acccatgtta gatgacgccg tgtctaggtc ttgtgctaag aaccatgagt taataccatc 120 aacaagacac gcatatttac ttac 144 <210> 2246 <211> 144 <212> DNA <213> Artificial Sequence <400> 2246 attgctataa tagactcttc tgttagttga tgagtcgtta aacaacactc gcatgttccc 60 gtttgaatat tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga 120 gaaatcagaa ttcaatacta aatt 144 <210> 2247 <211> 144 <212> DNA <213> Artificial Sequence <400> 2247 taccgaagtc tatccggtcc tcaaatttaa aggctcctgt tcgtaaacct gttgatggtg 60 ctttgacagg cgttgtaagg gaaggtcctg accatgcgtt tggtgcgaat gttgtagccc 120 acttaggatt aaacgcctca gaag 144 <210> 2248 <211> 144 <212> DNA <213> Artificial Sequence <400> 2248 gtaggacttc cttagagttc attgtccatg ttaccttatc cactacctcc cttgtggcta 60 ctgagtcttt atacttgagt agccatctag atgttttaac aacggaagct ttgtttgcta 120 caggtgcctt gtaggtaaat gggt 144 <210> 2249 <211> 144 <212> DNA <213> Artificial Sequence <400> 2249 ccgtcatttc agtacgattg aacaaagtaa tagcttgttc taagtcacca atgaataata 60 gtttatcatt tgtgtcgttt ttaaagatag cgtcaggaag tacaattacc tctttaccaa 120 acaatgtatt accacttgcc attg 144 <210> 2250 <211> 144 <212> DNA <213> Artificial Sequence <400> 2250 gcgtcatctg atacaatagt aacagagaca taaggagctt gagtgtcctg ccccactgtc 60 ataataccat tttcgtctgc ggtaatacct aaaacagcac tatatgctcc acccgcttgt 120 aagtcgacaa cattcaatga tacg 144 <210> 2251 <211> 144 <212> DNA <213> Artificial Sequence <400> 2251 ttgaccacct gttacagttg gtggtgttgc ttgccaacct gtggatggtg ctgttgtacc 60 tgaggtacct acagcgtaag taacagcgat agatttcaca ccattaccgg ttgagccatc 120 tacaggacta tagttcactg tata 144 <210> 2252 <211> 144 <212> DNA <213> Artificial Sequence <400> 2252 cgtctgttag ataccagttg tccgcgttgc ttatctttag ttaaagcagg gtttagttcc 60 gcagtaactt tacgtttgtc taagtagacg tccgtgtcct tttctagtaa tgcttgtaac 120 agtgcgtgtg tttgttgttg ctgt 144 <210> 2253 <211> 143 <212> DNA <213> Artificial Sequence <400> 2253 gtaggtttta tggtattagg tggcgcttgt ttggctacaa gttttaagct atcaaaggac 60 ttagagcagg ttgataacat caacgataaa ggagagagtc actaatggga atttttatca 120 gaaacaagcc acacgaagag cgg 143 <210> 2254 <211> 143 <212> DNA <213> Artificial Sequence <400> 2254 tttgctacag gtgcattgta ggtaaatggg ttttttgtaa ctggtttaat tccgttgttt 60 gattggatat gctcaaagtt ccaagtgaac ttcttacccg tttggtcacg tgtcattgta 120 cagcggaccc aagatgattt gta 143 <210> 2255 <211> 143 <212> DNA <213> Artificial Sequence <400> 2255 acccatttac ctacactgca cctgtagcaa acaaagcttc cgttgttaaa acatctagat 60 ggctactcaa gtataaagac tcagtagcca caagggaggt agtggataag gtaacatgga 120 caatgaaatc taaggaagtc cta 143 <210> 2256 <211> 143 <212> DNA <213> Artificial Sequence <400> 2256 ttaaccatgg agcgtattga cgcacgttta gaggacgtga gagagattaa aaaagagctg 60 tctggtgccc gtcaacaaat cgcggaccta gacaaacgtc tttcgcagtc aattgaccat 120 gttaacacac tagaggacga cat 143 <210> 2257 <211> 143 <212> DNA <213> Artificial Sequence <400> 2257 gccactatca gtggtgaggg tagacagtga gttaaaagat gggttctata atttaggtaa 60 gcctgaaatt gcaggcaagg ttgatgaagt tccaccgcgt cccaataaac caagcgggaa 120 acaatattta gtaatttatg ata 143 <210> 2258 <211> 143 <212> DNA <213> Artificial Sequence <400> 2258 tcaaccaatt caggtaaaca attgtttgac gtcttagcag atgacctact aacagatgac 60 caatatgagg gtttcttaat tggtaacatt tataagtaca ttaaacgcca caaagaaaaa 120 ggtggcagta ctgaccttga aaa 143 <210> 2259 <211> 143 <212> DNA <213> Artificial Sequence <400> 2259 attttccata cttctcgcct ctcctttttc taatttgtcc acgtcttcct ctaatgcttt 60 agcacgttcc gcgtccacag atttatcttt attttcttct ggttcaacct cgtctgcctc 120 atcatcctta ggttgttcat cct 143 <210> 2260 <211> 143 <212> DNA <213> Artificial Sequence <400> 2260 aacctagaga ggactgaggt atagattttc agatgaatgg gtcctttgtg gtagcagtag 60 ggtcagagtt agaaaacggg acatatagcg tggtttccaa taaaccaatc gcacaagcac 120 ccagagaatt aattaactgg cta 143 <210> 2261 <211> 143 <212> DNA <213> Artificial Sequence <400> 2261 ttaaccatgg agcgtcttga cgcacgttta gaggacgtga gagagattaa aaaagagctg 60 tctggtgccc gtcaacaaat cgcggaccta gacaaacgtc tttcgcagtc aattgaccat 120 gttaacaaac tagaggacga cat 143 <210> 2262 <211> 143 <212> DNA <213> Artificial Sequence <400> 2262 tgctgaacta ttgaatcgca gagaggacgt taccgcagac gagtttgtgt ggacgctatc 60 tgatgaggct aaggaaatgc gtgaggaact agtacgtagt aaaacacctg ttattgattt 120 agcctttaat agtggactat ttg 143 <210> 2263 <211> 143 <212> DNA <213> Artificial Sequence <400> 2263 tgctgaacta ttgaaacgca gagaggacgt taccgcagac gagtttgtgt ggacgctatc 60 tgatgaggct aaggaaatgc gtgaggaact agtacgtagt aaaacacctg ttattgattt 120 agccttttat agtggactat ttg 143 <210> 2264 <211> 143 <212> DNA <213> Artificial Sequence <400> 2264 ttctgttagt tgatgtgtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 60 tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca taattcaata 120 ctaaattatc atttgggtat tgg 143 <210> 2265 <211> 143 <212> DNA <213> Artificial Sequence <400> 2265 ttaaccatgg agcgtcttga cgcacgttta gaggacgtga gagagattaa aaaagagctg 60 tctggtgccc gtcaacaaat cgcggaccta gacaaacgtc tttcgcagtc aattgaccat 120 gttaacacac tagaggacga cat 143 <210> 2266 <211> 143 <212> DNA <213> Artificial Sequence <400> 2266 tgctgaacta ttgaatcgca gagaggacgt taccgcagac gagtttgtgt ggacgctatc 60 tgatgaggct aaggaaatgc gtgaggaact agtacgtagt aaaacacctg ttattgattt 120 agccttttat agtggactat ttg 143 <210> 2267 <211> 143 <212> DNA <213> Artificial Sequence <400> 2267 tacaaatcat cttgggtccg ctgtacaatg acacgtgacc aaacgggtaa gaagttcact 60 tggaactttg agcatatcca atcaaacaac ggaattaaac cagttacaaa aaacccattt 120 acctacactg cacctgtagc aaa 143 <210> 2268 <211> 143 <212> DNA <213> Artificial Sequence <400> 2268 aacctagaga ggactgaggt atagattttc agatgaatgg gtcctttgtg gtagcagtag 60 ggtcagagtt agaaaacggg acatatagcg tggtttccaa taaaccaatc gcacaagcac 120 ccagagactt aattaactgg cta 143 <210> 2269 <211> 142 <212> DNA <213> Artificial Sequence <400> 2269 gacagatatg cataatatgt attttatttt tgaccatgag gaatatattg agtcaaaatt 60 tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt gtacacaaag ccaaaatgta 120 cgtgcgtttg aaaattttcc ca 142 <210> 2270 <211> 142 <212> DNA <213> Artificial Sequence <400> 2270 catcaactaa cagaatagtc tattatagca atgacttatt aaccaactac ttgccagcag 60 gagttaaata ttccgtcaca atagacgcat tcagcaacaa taatgggtta attagggtag 120 gtaattttga cgctctcagt ac 142 <210> 2271 <211> 142 <212> DNA <213> Artificial Sequence <400> 2271 agcgcgtact aaaagtcccg cgataaaaga gtggcaagct caagagagtt acaaaacatt 60 aggtaaaata agaaacatga ataaaggggt cttatgtggg gaacaaaaca aattattagt 120 agtagactgt gacgtaaaag gt 142 <210> 2272 <211> 142 <212> DNA <213> Artificial Sequence <400> 2272 gttgcctgac tgtaaatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaagtc cctcaggaat at 142 <210> 2273 <211> 142 <212> DNA <213> Artificial Sequence <400> 2273 attgagggtt acctttgaca agttcgtata ccttgtcccc aactttacct aagaacgtac 60 ctactttatt atcactatca ccacttttaa actcttgcgc gtgtgggtaa atgacagagt 120 atagtagaaa ttcacgtaca tt 142 <210> 2274 <211> 142 <212> DNA <213> Artificial Sequence <400> 2274 gtagagttgc attatgatac taagtcagaa gatatttttg ttataagaaa tgatatgttc 60 ctatgggact aatgtctaat aaggaggaaa aataaatgat tactgtaacg attaataaat 120 ggcgaaaagc aaaagtgaca cc 142 <210> 2275 <211> 142 <212> DNA <213> Artificial Sequence <400> 2275 ttttattgtt tgacatgtac tgagagcgtc aaaattacct accctaatta acccattatt 60 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agatggttaa 120 taagtcagtg ctataataga ct 142 <210> 2276 <211> 142 <212> DNA <213> Artificial Sequence <400> 2276 gttgcctgac tgtatatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaattc cctcaggaat at 142 <210> 2277 <211> 142 <212> DNA <213> Artificial Sequence <400> 2277 tcattgggtt acctgtttta gattgtgttt caatgttctc tgtaacaaca acctctttta 60 ttccccctgt catggggtca taactcatgg cgttaccttc taatgttttc caaagttcaa 120 acatggtacg cgcgttctct tt 142 <210> 2278 <211> 142 <212> DNA <213> Artificial Sequence <400> 2278 gttgcctgac tgtatatagc gtaagtatta caataaatga ctagcatgcc agcgtctagt 60 tttgaaattg gtagctgttt aagttgtgga acaaggtcct cgtaaatcaa ccacccttcc 120 ttagtaagtc cctcaggaat at 142 <210> 2279 <211> 142 <212> DNA <213> Artificial Sequence <400> 2279 tcattgggtt acctgtttta gattgtgttt caatgttctc tgtaacaaca acctctttta 60 ttccccctgt catggggtca taactcatgg cgttaccttc taatgttttc caaagttcaa 120 acatggtccg cgcgttctct tt 142 <210> 2280 <211> 142 <212> DNA <213> Artificial Sequence <400> 2280 aatttagtat tgaagtatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctattatag ca 142 <210> 2281 <211> 142 <212> DNA <213> Artificial Sequence <400> 2281 tgctataata gactattctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt 60 ttgaatattc tatagtcgca ccatttcctg tccaaccatt aatagtgggg tctttcgaga 120 aatcatactt caatactaaa tt 142 <210> 2282 <211> 141 <212> DNA <213> Artificial Sequence <400> 2282 agtcacttgc aaagagcgga atcattagtt ctccatcaac gtcacagtgc aatagaggtg 60 tacggtattg gtagtcaata aaaatggtgt ctgtttcctt atctacatat gcaaaacaac 120 ccgcgtactc atcatatacg t 141 <210> 2283 <211> 141 <212> DNA <213> Artificial Sequence <400> 2283 aagttctgac accctaataa agatggcgtc tctcagtccc aaattaaatg ccacagtttc 60 ttctagtaaa atattcatgg tgacctctcc tctttacccc tcatgtctct cattaacaac 120 ataatcacag tcacttgcaa a 141 <210> 2284 <211> 141 <212> DNA <213> Artificial Sequence <400> 2284 gcgtttgttt gattatgcaa aatcctatat gaaagagtat cataatgtag agttgcatta 60 tgatactaag tcagaagata tttttgttat aagaaatgat atgttcctat gggaataatg 120 tctaataagg aggaaaaata a 141 <210> 2285 <211> 141 <212> DNA <213> Artificial Sequence <400> 2285 aaaagagagg gttctttccc tctcaatttg tttctattac tgtttggatg ttcttgtttg 60 ttgtgacaag aaaaacaaat actttctaaa taattcatat ctaacctatg ttcccatccc 120 tcagaggttc gtatctccgt g 141 <210> 2286 <211> 141 <212> DNA <213> Artificial Sequence <400> 2286 aaaagagagg gttatttccc tctcaatttg tttctattac tgtttggatg ttcttgtttg 60 ttgtgacaag aaaaacaaat actttctaaa taattcatat ctaacctatg ttcccatccc 120 tcagagggtc gtatctccgt g 141 <210> 2287 <211> 141 <212> DNA <213> Artificial Sequence <400> 2287 agtctattat agcaatgact tattaaccaa ctacttgcca gcaggagtta aatattccgt 60 cacaatagac gcattcagca acaatcatgg gttaattagg gtaggtaatt ttgacgctct 120 cagtacatgg caaacaataa a 141 <210> 2288 <211> 141 <212> DNA <213> Artificial Sequence <400> 2288 aacttctact aataactcat agttattcat cttcgttgtc ctcctcatct aacatactaa 60 gttcttcgcg taagaacttg acaacccctt ctaatagctc aattgtttcc tctttgttta 120 ggttctcacc ttccccctct a 141 <210> 2289 <211> 141 <212> DNA <213> Artificial Sequence <400> 2289 aatacccaaa tgataattta gtattgaatt atgatttctc gaaagacccc actattaatg 60 gttggacagg aaatggtgcg actatagaat attcaaacgg gaacatgcga gtgttgttta 120 acgactcttc aactaacaga a 141 <210> 2290 <211> 141 <212> DNA <213> Artificial Sequence <400> 2290 tgtactgaga gcgtcaaaat taccgaccct aattaaccca ttattgttgc tgaatgcgtc 60 tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata 120 atagactatt ctgttagttg a 141 <210> 2291 <211> 141 <212> DNA <213> Artificial Sequence <400> 2291 tggcaaacaa taaaacaagg tgacacacct tcaacgtata aatttgaggg tataaccgca 60 ggggcaacta atgcttttag tatacagggt aattcaaatg ctttaattat aactataaca 120 aaaataataa tcgaactagg a 141 <210> 2292 <211> 141 <212> DNA <213> Artificial Sequence <400> 2292 cgtcaggacg ggaagaaatt tcacaatacc cctgtttgga atattgtcta tagggtgttc 60 tatcgttagc ctctttctga acaataccac cacccgttgt tgctacccac gcgtgagagt 120 caacaatcaa caattctttt t 141 <210> 2293 <211> 141 <212> DNA <213> Artificial Sequence <400> 2293 gaaatttcac aatccccctg tttggaatat tgtctatagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aataaacaat 120 tctttttcag ggataggaat a 141 <210> 2294 <211> 141 <212> DNA <213> Artificial Sequence <400> 2294 gtaacgttac caatgtatgt gttagtaaat ggggtaaaat tgcctattaa tacattgttt 60 ggtgccacag gtgcagagtt taatgggtta tatgacccac gttttcaatt tctaacatgt 120 gtgattgtgc aattaattat g 141 <210> 2295 <211> 141 <212> DNA <213> Artificial Sequence <400> 2295 cgtcaggacg ggacgaaatt tcacaatacc cctgtttgga atattgtcta tagggtgttc 60 tatcgttagc ctctttctga acaataccac cacccgttgt tgctacccac gcgtgagagt 120 caacaatcaa caattctttt t 141 <210> 2296 <211> 141 <212> DNA <213> Artificial Sequence <400> 2296 gctataatag actattctgt tagttgatga gtcgttaaac aacactcgca tgttcccgtt 60 tgaatattct atagtcgcac catttcctgt ccaaccatta atagtggggt ctttcgagaa 120 atcataagtc aatactaaat t 141 <210> 2297 <211> 141 <212> DNA <213> Artificial Sequence <400> 2297 aatttagtat tgacttatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tcgattatag c 141 <210> 2298 <211> 141 <212> DNA <213> Artificial Sequence <400> 2298 cacggagata cgaccctctg agggatggga acataggtta gatatgaatt atttagaaag 60 tatttgtttt tcttgtcaca acaaacaaga acatccaaac agtaatagaa acaaattgag 120 agggaaagaa ccctctcttt t 141 <210> 2299 <211> 140 <212> DNA <213> Artificial Sequence <400> 2299 tccaaacagg ggtattgtga aatttcgtcc cgtcctgacg gtcagtgtga ttgggaggat 60 atgttaaatt gggttttggc gtttattgag acaaacaatt tagacgtaca aggtatttgt 120 tatgaccctg cacagtctca 140 <210> 2300 <211> 140 <212> DNA <213> Artificial Sequence <400> 2300 tcaggagcaa tcaaggctat ctggaactgg ttacaaattc tattctttgc taaaatcata 60 aaaggagtca aaggacttgc ctctggtttt ggtaatacaa tcagtggtat gtggacaagt 120 gtcaaaatct ttttcactac 140 <210> 2301 <211> 140 <212> DNA <213> Artificial Sequence <400> 2301 agagagttac aatacattag gtaaaataag aaacatgaat aaaggggtct tatgtgggga 60 acaaaacaaa ttattagtag tagactgtga cgtaaaaggt aaagcaaacg gaatacactc 120 ttttactacc ttaatgaaag 140 <210> 2302 <211> 140 <212> DNA <213> Artificial Sequence <400> 2302 tttaaaggag gactaaagat gttaggttgt gattattgta aatttgaacc aatgagggag 60 acactatttt cctcagatta cttatggagt gggaggactg acatgactga ggtgtttata 120 aacgggaaaa ctatgacagt 140 <210> 2303 <211> 140 <212> DNA <213> Artificial Sequence <400> 2303 ttgtaactct ctagagcttg ccactctttt atcgcgggaa ttttagtacg cgctttgaga 60 ggaaacccct taaattggtt gtatttcatt gtatcactcc ttagaacaaa cgcataagta 120 tataaaccaa tactgtaatc 140 <210> 2304 <211> 140 <212> DNA <213> Artificial Sequence <400> 2304 accccactaa cttttttaaa catcccgttt tcagcaataa cattgtctga tacaatatta 60 ttaattgaca tcccccagtt ttcccacgct gtaccgttcc attttagcac agtagggtca 120 ttaggttatt gccataatgt 140 <210> 2305 <211> 140 <212> DNA <213> Artificial Sequence <400> 2305 ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat gttcccgtgt 60 gaatattcta tagtcgcacc atttcctgtc caaccattaa tagtggggtc tttcgagaaa 120 tcataattca atactaaatt 140 <210> 2306 <211> 140 <212> DNA <213> Artificial Sequence <400> 2306 accccactaa ctattttaaa catcccgttt tcagcaataa cattgtctga tacaatatta 60 ttaattgaca tcccccagtt ttcccacgct gtaccgttcc attttagcac agtagggtca 120 ttaggttttt gccataatgt 140 <210> 2307 <211> 140 <212> DNA <213> Artificial Sequence <400> 2307 tttaaaggag gaataaagat gttaggttgt gattattgta aatttgaacc aatgagggag 60 acactatttt cctcagatta cttatggagt gggaggactg acatgactga ggtgtttata 120 aacgggacaa ctatgacagt 140 <210> 2308 <211> 140 <212> DNA <213> Artificial Sequence <400> 2308 tcaggagcaa tctaggctat ctggaactgg ttacaaattc tattctttgc taaaatcata 60 aaaggagtca aaggacttgc ctctggtttt ggtaatacaa tcagtggtat gtggacaagt 120 gtcaaaaact ttttcactac 140 <210> 2309 <211> 140 <212> DNA <213> Artificial Sequence <400> 2309 gtcaggacgg gaagaaattt cacaataccc ctgtttggaa tattgtctat agggtgttct 60 atcgttagcc tctttctgaa caataccacc acccgttgtt gctacccacg cgtgagagtc 120 aacaatatac aattcttttt 140 <210> 2310 <211> 140 <212> DNA <213> Artificial Sequence <400> 2310 accccactaa ctattttaaa catcccgttt tcagcaataa cattgtctga tacaatatta 60 ttaattgaca tcccccagtt ttcccacgct gtaccgttcc attttagcac agtagggtca 120 ttaggttatt gccataatgt 140 <210> 2311 <211> 140 <212> DNA <213> Artificial Sequence <400> 2311 tcaggagcaa tctaggctat ctggaactgg ttacaaattc tattctttgc taaaatcata 60 aaaggagtca aaggacttgc ctctggtttt ggtaatacaa tcagtggtat gtggacaagt 120 gtcaaaatct ttttcactac 140 <210> 2312 <211> 140 <212> DNA <213> Artificial Sequence <400> 2312 tttaaaggag gactaaagat gttaggttgt gattattgta aatttgaacc aatgagggag 60 acactatttt cctcagatta cttatggagt gggaggactg acatgactga ggtgtttata 120 aacgggacaa ctatgacagt 140 <210> 2313 <211> 140 <212> DNA <213> Artificial Sequence <400> 2313 gtcaggacgg gacgaaattt cacaataccc ctgtttggaa tattgtctat agggtgttct 60 atcgttagcc tctttctgaa caataccacc acccgttgtt gctacccacg cgtgagagtc 120 aacaatatac aattcttttt 140 <210> 2314 <211> 139 <212> DNA <213> Artificial Sequence <400> 2314 actatatgtt ttgacagata tgcataatat gtattttatt tttgaccatg aggaatatat 60 tgagtcaaaa tttgaactga aagaaaagga ggctgtaaag gaaacgggaa ttgtacacaa 120 agccaaaatg tacgtgcgt 139 <210> 2315 <211> 139 <212> DNA <213> Artificial Sequence <400> 2315 taaggaaatg cgtgaggacc tagtacgtag taaaacacct gttattgatt tagcctttaa 60 tagtggacta tttgagcaca cgggtaatga gggtgacctt gttgaattga aactcttcac 120 ggacggtatt cttctagca 139 <210> 2316 <211> 139 <212> DNA <213> Artificial Sequence <400> 2316 ccttttcttg tatagactct ttaccaaaca attgtaataa aagaaagtag tcagcgttct 60 ctatctctga gagttgccag ctactttcta agagggatga atatgtttcc tcaagggttt 120 ctaactgttc ctcaaaggt 139 <210> 2317 <211> 139 <212> DNA <213> Artificial Sequence <400> 2317 ttcattaact cagattgggc tacagacact ttagaagtaa ctgtgaagaa ccaacgaacc 60 tacttgtaat aacatctagc cactcgccaa agagtggctt ttttatggta taattaataa 120 agaaacacgt gtaaggggg 139 <210> 2318 <211> 139 <212> DNA <213> Artificial Sequence <400> 2318 ccttttcttg tttagactct ttaccaaaca attgtaataa aagaaagtag tcagcgttct 60 ctatctctga gagttgccag ctactttcta agagggatga atatgtttcc tcaagggttt 120 ctaactggtc ctcaaaggt 139 <210> 2319 <211> 139 <212> DNA <213> Artificial Sequence <400> 2319 cgcattcagc aacaataatg ggttaattag ggtaggtaat tttgacgctc tcagtacatg 60 gcaaacaata aaacaaggtg acacaccttc aacgtataaa tttgagggta taaccgcagg 120 ggcaactcat gcttttagt 139 <210> 2320 <211> 139 <212> DNA <213> Artificial Sequence <400> 2320 cggggaattc atcatctaca gcgcaaaacg aggcagacta tcatatgcgc agacccgtca 60 acagtgggtt cttctcgcac gtagtaggta acgggcgagt aattcaaaca gcacgcacaa 120 acgcgggatt ttatgacgt 139 <210> 2321 <211> 139 <212> DNA <213> Artificial Sequence <400> 2321 cccccttaca cttgtttctt tattaattat accataaaaa agccactctt tggcgagtgg 60 ctagatgtta ttacaagtag gttcgttggt tcttcacagt tacttctaaa gtgtctgtag 120 cccaatcgga gttaatgaa 139 <210> 2322 <211> 139 <212> DNA <213> Artificial Sequence <400> 2322 ttttatgacg ttggtggcgg atggaactcg tggggatatg cggcaattga attgattgaa 60 tcgcacaaaa ccaaagaaga gtttatgaaa gactataagc tactagtaga attaattcgt 120 ctattatgtg atgaagcgg 139 <210> 2323 <211> 139 <212> DNA <213> Artificial Sequence <400> 2323 tattgtttgc catgtactga gagcgtcaaa attacctacc ctaattaacc cattattgtt 60 gctgaatgcg tctattgtga cggaatattt aactcctgct ggcaagtagt tggttaataa 120 gtcattgata taatagact 139 <210> 2324 <211> 139 <212> DNA <213> Artificial Sequence <400> 2324 ccttttcttg tatagactct ttaccaaaca attgtaataa aagaaagtag tcagcgttct 60 ctatctctga gagttgccag ctactttcta agagggatga atatgtttcc tcaagggttt 120 ctaactggtc ctcaaaggt 139 <210> 2325 <211> 139 <212> DNA <213> Artificial Sequence <400> 2325 cccccttaca cgtgtttctt tattaattat accataaaaa agccactctt tggcgagtgg 60 ctagatgtta ttacaagtag gttcgttggt tcttcacagt tacttctaaa gtgtctgtag 120 cccaatcgga gttaatgaa 139 <210> 2326 <211> 138 <212> DNA <213> Artificial Sequence <400> 2326 cgatatacca ttgttggagt aggcagcctt ttcgtgcagg ttgatggtat tgatgaatgg 60 ttctactatg accgttttga acgtgactat gttattgagg gaattgaata tagtttgaat 120 gataaacatg gtgctacc 138 <210> 2327 <211> 138 <212> DNA <213> Artificial Sequence <400> 2327 tctgatgagg ctaaggaaat gcgtgaggac ctagtacgta gtaaaacacc tgttattgat 60 ttagccttta atagtggact atttgagcac acgggtaatg agggtgacct tgttgaattg 120 aaactcttca cggacggt 138 <210> 2328 <211> 138 <212> DNA <213> Artificial Sequence <400> 2328 tagtgttatt ataccattta tgtgtaaaac gttgttatac tagctcatac gcaacatcaa 60 ggttacctaa atcattttta gcaatcttaa caataacaaa ctcatcctca acttcatcct 120 ggtccccatc cacgcgta 138 <210> 2329 <211> 138 <212> DNA <213> Artificial Sequence <400> 2329 ttgttacaga gaacattgaa acacaatcta aaaaaggtaa cccaatgaga cgcctgaaac 60 tccgtgagac acgcacaggt agggaggctg tttcttactt aatgacttgg aaacctgatt 120 ttacacgttg ggaggaca 138 <210> 2330 <211> 138 <212> DNA <213> Artificial Sequence <400> 2330 agggtagaca ttgagttaaa agatgggttc tataatttag gtaagcctga aattgcaggc 60 aaggttgatg aagttccacc gcgtcccaat aaaccaagcg ggaaacaata tttagtaatt 120 tatgatagtg aggtattt 138 <210> 2331 <211> 138 <212> DNA <213> Artificial Sequence <400> 2331 ccggatggaa gtgtaagtaa acctcagatt gtaaatatct tgcgtagtaa accagataca 60 aacctaacgt cctacggttg gttgtatgct attaccatgt ataccctttt atatgggtct 120 gcgtttgcaa tcattaga 138 <210> 2332 <211> 138 <212> DNA <213> Artificial Sequence <400> 2332 agggtagaca gtgagttaaa agatgggttc tataatttag gtaagcctga aattgcaggc 60 aaggttgatg aagttccacc gcgtcccaat aaaccaagcg ggaaacaata tttagtaatt 120 tatgatattg aggtattt 138 <210> 2333 <211> 138 <212> DNA <213> Artificial Sequence <400> 2333 ctccttacct acaggcggtt ctactgtacc tgtaacaata acaggtgtca cttttgcttt 60 tcgccattta ttaatcgtta cagtaatcat ttatttttcc tccttattag acattattcc 120 cataggacca tatcattt 138 <210> 2334 <211> 138 <212> DNA <213> Artificial Sequence <400> 2334 ttaacgactc atcaactaac agaatagtct attatagcaa tgacttatta accaactact 60 tgccagcagg agttaaatat tccgtcacaa tagacgcatt cagcaacaat aatgggttaa 120 ttagggtcgg taattttg 138 <210> 2335 <211> 138 <212> DNA <213> Artificial Sequence <400> 2335 ttactaagga cgggtggttg atttacgagg accttgttcc acaacttaaa cagctaccaa 60 tttcaaaact agacgctggc atgctagtca tttattgtaa tacttacgct atttacagtc 120 aggcaactca agaggtat 138 <210> 2336 <211> 138 <212> DNA <213> Artificial Sequence <400> 2336 aacttaatga atagtacaac ctcacaaaac ctaaacggac actatcatat ggaggaatat 60 ccaatgacta tgaaagtatt aacaggtgag gtagaggctg aacactactt agctctatgg 120 tgggaaatgg atagtttt 138 <210> 2337 <211> 138 <212> DNA <213> Artificial Sequence <400> 2337 aacttaatga ttagtacaac ctcacaaaac ctaaacggac actatcatat ggaggaatat 60 ccaatgacta tgaaagtatt aacaggtgag gtagaggctg aacactactt agctctatgg 120 tgggaaaggg atagtttt 138 <210> 2338 <211> 138 <212> DNA <213> Artificial Sequence <400> 2338 ctccttacct ccaggcggtt ctactgtacc tgtaacaata acaggtgtca cttttgcttt 60 tcgccattta ttaatcgtta cagtaatcat ttatttttcc tccttattag acattattcc 120 cataggaaca tatcattt 138 <210> 2339 <211> 138 <212> DNA <213> Artificial Sequence <400> 2339 tctaatgatt tcaaacgcag acccatataa aagggtatac atggtaatag catacaacca 60 accgtaggac gttaggtttg tatctggttt actacgcaag atatttacaa tctgaggttt 120 acttacaatt ccatccgg 138 <210> 2340 <211> 138 <212> DNA <213> Artificial Sequence <400> 2340 acacgtttag tgttttgtag gtaatatcca ctgacccatc ctgaggcagg tattttctta 60 cctgagttct tagttacata ataccattgg ttgtttttaa taatcttttg acccgtttga 120 cgtttgggtg tttcaaac 138 <210> 2341 <211> 138 <212> DNA <213> Artificial Sequence <400> 2341 gtttgaaaca cccaaacgtc aaacgggtca aaagattatt aaaaacaacc aatggtatta 60 tgtaactaag aactcaggta agaaaatacc tgcctcagga tgggtcagtg gatattacct 120 acaaaaccct aaacgtgt 138 <210> 2342 <211> 138 <212> DNA <213> Artificial Sequence <400> 2342 tctaatgatt tcaaacgcag acccatataa aagggtatac atggtaatag catacaacca 60 accgtaggac gttaggtttg tatctggttt actacgcaag atatttacaa tctgaggttt 120 acttacactt ccatccgg 138 <210> 2343 <211> 138 <212> DNA <213> Artificial Sequence <400> 2343 agggtagaca gtgagttaaa agatgggttc tataatttag gtaagcctga aattgcaggc 60 aaggttgatg aagttccacc gcgtcccaat aaaccaagcg ggaaacaata tttagtaatt 120 tatgatagtg aggtattt 138 <210> 2344 <211> 138 <212> DNA <213> Artificial Sequence <400> 2344 ctccttacct ccaggcggtt ctactgtacc tgtaacaata acaggtgtca cttttgcttt 60 tcgccattta ttaatcgtta cagtaatcat ttatttttcc tccttattag acattattcc 120 cataggacca tatcattt 138 <210> 2345 <211> 138 <212> DNA <213> Artificial Sequence <400> 2345 aacttaatga atagtacaac ctcacaaaac ctaaacggac actatcatat ggaggaatat 60 ccaatgacta tgaaagtatt aacaggtgag gtagaggctg aacactactt agctctatgg 120 tgggaaaggg atagtttt 138 <210> 2346 <211> 137 <212> DNA <213> Artificial Sequence <400> 2346 ggggatgaaa ttaatgaaca ctattttcac accaactaag caacaaaaag agaacgcgcg 60 taccatgttt gaactttgga aaacattaga aggtaacgcc atgagttatg accccatgac 120 agggggaata aaagagg 137 <210> 2347 <211> 137 <212> DNA <213> Artificial Sequence <400> 2347 gttcaacgga gacggtcaac tatatgtttt gacagatatg cataatatgt attttatttt 60 tgaccatgag gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga 120 aacgggaatt gtacaca 137 <210> 2348 <211> 137 <212> DNA <213> Artificial Sequence <400> 2348 ggtaattaat tgagactgtg cagggtcata acaaatacct tgtacgtcta aattgtttgt 60 ctcaataaac gccaaaaccc aatttaacat atcctcccaa tcacactgac cgtcaggacg 120 ggacgaaatt tcacaat 137 <210> 2349 <211> 137 <212> DNA <213> Artificial Sequence <400> 2349 tcagacacct tagacgcaag gcacactact acgagtttct ttagccctga ttttttaaac 60 gattctaatg ccatgagtgt cttgccagag ccaacctcac tatgatttag attatgtgtt 120 tcccatttgt ctatgac 137 <210> 2350 <211> 137 <212> DNA <213> Artificial Sequence <400> 2350 agtcacagtt actaaagcac tgaagacaag taactcagca gactcaatac ccgtgttctc 60 atttaactca cgcgcctttt caaccactaa atcacctaat tttgtagtat ctaaattcat 120 gtctattttc ctccctt 137 <210> 2351 <211> 137 <212> DNA <213> Artificial Sequence <400> 2351 ttcccaccag agagctaagt agtgttcagc ctctacctca cctgttaata ctttcatagt 60 cattggatat tcctccatat gatagtgtcc gtttaggttt tgtgaggttg tactaatcat 120 taagttaagg ggttgta 137 <210> 2352 <211> 137 <212> DNA <213> Artificial Sequence <400> 2352 ttgtttgcca tgtactgaga gcgtcaaaat tacctaccct aattaaccca ttattgttgc 60 tgaatgcgtc tattgtgacg gaatatttaa ctcctgctgg caagtagttg gttaataagt 120 cattgctcta atagact 137 <210> 2353 <211> 137 <212> DNA <213> Artificial Sequence <400> 2353 tagcgcctga ggttgctgag gaatttagca aacgcgtacc atactggtct aacagtaaag 60 caaaaatgag cggtaagcgt ggttcatata tgggtgagca tatgagagac catgttatct 120 atagcaatgc caaagat 137 <210> 2354 <211> 137 <212> DNA <213> Artificial Sequence <400> 2354 aatttagtag tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctatta 137 <210> 2355 <211> 137 <212> DNA <213> Artificial Sequence <400> 2355 ctcctaactt tgattgtatg ctagtctatt tatcatttta ctcatgtagt caacttggtt 60 ctgtaacgtg tctactgcgt tatcttgagt gctatatccg tttagttcat aaatgaggtc 120 gtccatgtct aacgcgt 137 <210> 2356 <211> 137 <212> DNA <213> Artificial Sequence <400> 2356 ctcctaactg tgattgtatg ctagtctatt tatcatttta ctcatgtagt caacttggtt 60 ctgtaacgtg tctactgcgt tatcttgagt gctatatccg tttagttcat aaatgaggtc 120 gtccatggct aacgcgt 137 <210> 2357 <211> 137 <212> DNA <213> Artificial Sequence <400> 2357 tagcgcctgt ggttgctgag gaatttagca aacgcgtacc atactggtct aacagtaaag 60 caaaaatgag cggtaagcgt ggttcatata tgggtgagca tatgagagac catgttatct 120 atagcaaagc caaagat 137 <210> 2358 <211> 137 <212> DNA <213> Artificial Sequence <400> 2358 aatttagtag tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctatta 137 <210> 2359 <211> 137 <212> DNA <213> Artificial Sequence <400> 2359 ctcctaactg tgattgtatg ctagtctatt tatcatttta ctcatgtagt caacttggtt 60 ctgtaacgtg tctactgcgt tatcttgagt gctatatccg tttagttcat aaatgaggtc 120 gtccatgtct aacgcgt 137 <210> 2360 <211> 137 <212> DNA <213> Artificial Sequence <400> 2360 tagcgcctgt ggttgctgag gaatttagca aacgcgtacc atactggtct aacagtaaag 60 caaaaatgag cggtaagcgt ggttcatata tgggtgagca tatgagagac catgttatct 120 atagcaatgc caaagat 137 <210> 2361 <211> 136 <212> DNA <213> Artificial Sequence <400> 2361 tactatgacc gttttgaacg tgactatgtt aatgagggaa ttgaatatag tttgaaagat 60 aaacatggtg ctaccttgag tgtcgctagg ttatataaag ataaaacagt gattaaaatt 120 actgatttta cgaatg 136 <210> 2362 <211> 136 <212> DNA <213> Artificial Sequence <400> 2362 ttaagttgtg gaacaaggtc ctcgtaaatc aaccaccctt ccttagtaag tccctcagga 60 atatcgtcta atgaaagttg ttcataatta tataactctt gttcttcttg ctcgcgctca 120 atacgctcct cttttg 136 <210> 2363 <211> 136 <212> DNA <213> Artificial Sequence <400> 2363 ccatacaaac gaagtaaaat tatcagtaat gtcatccttg cctttgacaa ctttagctga 60 tatactgatt gtaccctcac catttacaaa aaactgttta gacggtgtaa taattacctc 120 agacggacta ctgttg 136 <210> 2364 <211> 136 <212> DNA <213> Artificial Sequence <400> 2364 acgcaacatc aaggttacct aaatcatttt tagcaatctt aacaataaca aactcatcct 60 caacttcatc ctgttcccca tccacgcgta gagtcacttt cttttctatt tcttgctcct 120 gtaaacgcat tccctc 136 <210> 2365 <211> 136 <212> DNA <213> Artificial Sequence <400> 2365 tttgctcaat tggatacgtt gaaagacgca gacggacgat acattattca accaaacgta 60 gcaatggcaa gtggtaaaac attgtttggt aaagaggtaa ttgtacttcc tgacgctatc 120 tttaaaatcg acacaa 136 <210> 2366 <211> 136 <212> DNA <213> Artificial Sequence <400> 2366 tacaaatcat cttggttccg ctgtacaatg acacgtgacc aaacgggtaa gaagttcact 60 tggaactttg agcatatcca atcaaacaac ggaattaaac cagttacaaa aaacccattt 120 acctacactg cacctg 136 <210> 2367 <211> 136 <212> DNA <213> Artificial Sequence <400> 2367 tgtacgccat ttcccactcg tctacagaaa tgtatgacgt tgcttggtcc gcaacccaaa 60 aattaagctc cttagttagg aagttggtga gattaccttt agcctctccc tctgtctttt 120 tagcccgttt gtgttc 136 <210> 2368 <211> 136 <212> DNA <213> Artificial Sequence <400> 2368 ttgatatgtt caaaaccatg cacccacatt tagccaatgt gaatgtaact cagtcaaaaa 60 taactgagtc ccttacctca ttctttgaac gatttgacag tgactacagg caactcaaag 120 cgtggtaccc tatacg 136 <210> 2369 <211> 136 <212> DNA <213> Artificial Sequence <400> 2369 ccatacaatc gaagtaaaat tatcagtaat gtcatccttg cctttgacaa ctttagctga 60 tatactgatt gtaccctcac catttacaaa aaactgttta gacggtgtaa taattacctc 120 agacggaata ctgttg 136 <210> 2370 <211> 136 <212> DNA <213> Artificial Sequence <400> 2370 tacaaatcct cttggttccg ctgtacaatg acacgtgacc aaacgggtaa gaagttcact 60 tggaactttg agcatatcca atcaaacaac ggaattaaac cagttacaaa aaacccattt 120 acctacaatg cacctg 136 <210> 2371 <211> 136 <212> DNA <213> Artificial Sequence <400> 2371 ttcactagtt ccgtcagaca ctagtgttgg ttgttcagat tgcccactag gtcttatatt 60 tgggttaggt tcgtcattga atgagaaacg gtctgttcct gtttcgttga aagcgtatgc 120 ggtacgtacc tcccca 136 <210> 2372 <211> 136 <212> DNA <213> Artificial Sequence <400> 2372 ctaatgcgcc acacactgct ctgtaaaatt ggtcatgctc tagataatga acaggaacta 60 gaggcgcaac gattaggtaa actattatgg aacctagaga acgacaattc agaagaacaa 120 acagagtctg attggg 136 <210> 2373 <211> 136 <212> DNA <213> Artificial Sequence <400> 2373 ggacgggaag aaatttcaca atacccctgt ttggaatatt gtctataggg tgttctatcg 60 ttagcctctt tctgaacaat accaccaccc gttgttgcta cccacgcgtg agagtcaaca 120 ataaacactt cttttt 136 <210> 2374 <211> 136 <212> DNA <213> Artificial Sequence <400> 2374 gagcgcaaac gtaactaagt tttggatgaa agtaagtaag aaagcaggac acacctattt 60 aatgagcgga actccaattt ctaacggaat gttagaacaa tggttttctc aattgaaaat 120 cgcaggtgta tactct 136 <210> 2375 <211> 136 <212> DNA <213> Artificial Sequence <400> 2375 tcttttttta atactttaaa tgaaagtcct atatcaatca tcatttttat accattctga 60 aatgttaatt taaccgcgtt acctactgac ccactgctta taatcttata ttcaatcatc 120 taatcacccc caatca 136 <210> 2376 <211> 136 <212> DNA <213> Artificial Sequence <400> 2376 agtaatcatt tatttttcct ccttattaga cattattccc ataggaacat atcatttctt 60 ataacaaaaa tatcttctga cttagtatca taatgcaact ctacattatg atactctttc 120 atataggatt ttgcat 136 <210> 2377 <211> 136 <212> DNA <213> Artificial Sequence <400> 2377 gagcgcaatc gtaactaagt tttggatgaa agtaagtaag aaagcaggac acacctattt 60 aatgagcgga actccaattt ctaacggaat gttagaacaa tggttttctc aattgaaaat 120 cgcaggttta tactct 136 <210> 2378 <211> 136 <212> DNA <213> Artificial Sequence <400> 2378 ttgaaacaac caaacgtcaa acgggtcaaa agattattaa aaacaaccaa tggtattatg 60 taactaagaa ctcaggtaag aaaatacctg cctcaggatg ggtcagtgga tattacctac 120 aaaaccctaa acgtgt 136 <210> 2379 <211> 136 <212> DNA <213> Artificial Sequence <400> 2379 tgtacgcctt ttcccactcg tctacagaaa tgtatgacgt tgcttggtcc gcaacccaaa 60 aattaagctc cttagttagg aagttggtga gattaccttt agcctctccc tctgtctttt 120 tagcccgatt gtgttc 136 <210> 2380 <211> 136 <212> DNA <213> Artificial Sequence <400> 2380 tacgctagag aatacttttt caactaattt gcttgggtta gttgcgtagt cccaaacgtc 60 accaacaaca ctgctaacct tatcaaacgc acttttagcc atgtttttgg caccgttcca 120 gatgtttatt acgcct 136 <210> 2381 <211> 136 <212> DNA <213> Artificial Sequence <400> 2381 atgcaaaaac ctatatgaaa gagtatcata atgtagagtt gcattatgat actaagtcag 60 aagatatttt tgttataaga aatgatatgt tcctatggga ataatgtcta ataaggagga 120 aaaataattg attact 136 <210> 2382 <211> 136 <212> DNA <213> Artificial Sequence <400> 2382 ttaaaacgtg ggttcctttt cgtccccaca tcgttacgtt cttaccttta gggataaccg 60 cttgaccact tgggtcaata accatttcag caccacgtcc atcattgaca gtcatgggac 120 catctaccgg gtgacc 136 <210> 2383 <211> 136 <212> DNA <213> Artificial Sequence <400> 2383 aatttagtct tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tctatt 136 <210> 2384 <211> 136 <212> DNA <213> Artificial Sequence <400> 2384 aatttagtct tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaagag tctatt 136 <210> 2385 <211> 136 <212> DNA <213> Artificial Sequence <400> 2385 ggacgggacg aaatttcaca atacccctgt ttggaatatt gtctataggg tgttctatcg 60 ttagcctctt tctgaacaat accaccaccc gttgttgcta cccacgcgtg agagtcaaca 120 ataaacactt cttttt 136 <210> 2386 <211> 136 <212> DNA <213> Artificial Sequence <400> 2386 gagcgcaatc gtaactaagt tttggatgaa agtaagtaag aaagcaggac acacctattt 60 aatgagcgga actccaattt ctaacggaat gttagaacaa tggttttctc aattgaaaat 120 cgcaggtgta tactct 136 <210> 2387 <211> 136 <212> DNA <213> Artificial Sequence <400> 2387 ccatacaatc gaagtaaaat tatcagtaat gtcatccttg cctttgacaa ctttagctga 60 tatactgatt gtaccctcac catttacaaa aaactgttta gacggtgtaa taattacctc 120 agacggacta ctgttg 136 <210> 2388 <211> 136 <212> DNA <213> Artificial Sequence <400> 2388 tgtacgccat ttcccactcg tctacagaaa tgtatgacgt tgcttggtcc gcaacccaaa 60 aattaagctc cttagttagg aagttggtga gattaccttt agcctctccc tctgtctttt 120 tagcccgatt gtgttc 136 <210> 2389 <211> 136 <212> DNA <213> Artificial Sequence <400> 2389 tacaaatcct cttggttccg ctgtacaatg acacgtgacc aaacgggtaa gaagttcact 60 tggaactttg agcatatcca atcaaacaac ggaattaaac cagttacaaa aaacccattt 120 acctacactg cacctg 136 <210> 2390 <211> 136 <212> DNA <213> Artificial Sequence <400> 2390 atgcaaaatc ctatatgaaa gagtatcata atgtagagtt gcattatgat actaagtcag 60 aagatatttt tgttataaga aatgatatgt tcctatggga ataatgtcta ataaggagga 120 aaaataattg attact 136 <210> 2391 <211> 135 <212> DNA <213> Artificial Sequence <400> 2391 gacggtcaac tatatgtttt gacagatatg cataatatgt attttatttt tgaccatgag 60 gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 120 gtacacaaag ccaaa 135 <210> 2392 <211> 135 <212> DNA <213> Artificial Sequence <400> 2392 tcctccggtg cgtgtaccgc gtgagacaac aatttgagca tgaacagcct caggtttgtt 60 ctcatagacg catgacccta tgaactcaca taatgctttt tcacttagtg ggtcagtaaa 120 gaagttgacc gcttg 135 <210> 2393 <211> 135 <212> DNA <213> Artificial Sequence <400> 2393 tccgtcaata cctaaaccaa acttcatatt tcctactggt tttccgcttt gcaccatgtg 60 ttaatcagct ccttttttct ctagcttttc aaggtcctca ggacttaaga aacgcttaat 120 aaagtcagcg ccatc 135 <210> 2394 <211> 135 <212> DNA <213> Artificial Sequence <400> 2394 cgatttaatt atgattgata aacaagttaa ccgcaacaag attgaccctc ttgacgcgct 60 tataaacgcg tacagtgaag catactttta tgagttcgag gaaataaact ggtcagaacg 120 ttacgcacgc ggtga 135 <210> 2395 <211> 135 <212> DNA <213> Artificial Sequence <400> 2395 cccactattg acggtgaaac cagttggcaa tttcgtacct ctgtagtttt catttagacc 60 aatttcgtct ttaattggct ctgtagcgtc tttgttttct tcattgccaa actgtaggac 120 tttaccggtt tcgtt 135 <210> 2396 <211> 135 <212> DNA <213> Artificial Sequence <400> 2396 aataaacggg tcagaacgtt acgcaagcgg tgattttggt tttggactgt aataaacgaa 60 cgaggcaacc caactagggt tgtctttttc gtgttataat ttataaagaa gttataattg 120 gaggaggttc accat 135 <210> 2397 <211> 135 <212> DNA <213> Artificial Sequence <400> 2397 atctaaaacc tcaatctcat tcatttgtaa ctcacctttt tcaacctttt ccattttact 60 gtagtatgct aaaatctcgc gcattgttcg tacagttact ttctccgctg taaatgtttg 120 ttttttaact tttac 135 <210> 2398 <211> 135 <212> DNA <213> Artificial Sequence <400> 2398 cccactagtg acggtgaaac cagttggcaa tttcgtacct ctgtagtttt catttagacc 60 aatttcgtct ttaattggct ctgtagcgtc tttgttttct tcattgccaa actgtaggac 120 tttaccgttt tcgtt 135 <210> 2399 <211> 135 <212> DNA <213> Artificial Sequence <400> 2399 atggtgaccc tcctccaatt ataacttctt tataaattat aacacgaaaa agacaaccct 60 agttgggttg cctcgttcgt ttattacagt ccaaaaccaa aatcaccgct tgcgtaacgt 120 tctgaccagt ttatt 135 <210> 2400 <211> 135 <212> DNA <213> Artificial Sequence <400> 2400 tgctggctag tagttggtta ataagtcatt gctataatag actcttctgt tagttgatga 60 gtcgttaaac aacactcgca tgttcccgtt tgaatattct atagtcgcac catttcctgt 120 ccaaccatta atagt 135 <210> 2401 <211> 135 <212> DNA <213> Artificial Sequence <400> 2401 atggtgaccc tcctccaatt ataacttctt tataaattat aacacgaaaa agacaaccct 60 agttgggttg cctcgttcgt ttattacagt ccaaaaccaa aatcaccgct tgcgtaacgt 120 tctgacccgt ttatt 135 <210> 2402 <211> 135 <212> DNA <213> Artificial Sequence <400> 2402 cccactagtg acggtgaaac cagttggcaa tttcgtacct ctgtagtttt catttagacc 60 aatttcgtct ttaattggct ctgtagcgtc tttgttttct tcattgccaa actgtaggac 120 tttaccggtt tcgtt 135 <210> 2403 <211> 135 <212> DNA <213> Artificial Sequence <400> 2403 atctaaatcc tcaatctcat tcatttgtaa ctcacctttt tcaacctttt ccattttact 60 gtagtatgct aaaatctcgc gcattgttcg tacagttact ttctccgctg taaatgtttg 120 ttttttaact tttac 135 <210> 2404 <211> 134 <212> DNA <213> Artificial Sequence <400> 2404 aagggaggaa aatagacatg aatttagata ctacaaaatt aggtgattta gtggttgaaa 60 aggcgcgtga gttaaatgag aaaacgggta ttgagtctgc tgagttactt gtcttcagtg 120 ctttagtaac tgtg 134 <210> 2405 <211> 134 <212> DNA <213> Artificial Sequence <400> 2405 cgcgcgtacc atgtttgaac tttggaaaac attagaaggt aacgccatga gttatgaccc 60 catgacaggg ggaataaaag aggttgttgt tacagagaac attgaaacac aatctaaaaa 120 aggtaaccca atga 134 <210> 2406 <211> 134 <212> DNA <213> Artificial Sequence <400> 2406 tgctgaatgc gtctattgtg acggaatatt taactcctgc tggcaagtag ttggttaata 60 agtcattgct ataatagact attctgttag ttgatgagtc gttaaacaac actcgcatgt 120 tcccgtttga atat 134 <210> 2407 <211> 134 <212> DNA <213> Artificial Sequence <400> 2407 ggacgggacg aaatttcaca atacccctgt ttggaatatt gtctataggg tgttctatcg 60 ttagcctctt tctgaacaat accaccaccc gttgttgcta cccacgcgtg agagtcaaca 120 ataaacaatt cttt 134 <210> 2408 <211> 134 <212> DNA <213> Artificial Sequence <400> 2408 ttgtcaatga ctgtcatcaa cttttttaat tagaattatg ttataataga atgagaacat 60 tatgaggagg ttataagatg gcacagcctg tctttttacg aaactttaca ttaaatggtg 120 tagatatagg tgag 134 <210> 2409 <211> 134 <212> DNA <213> Artificial Sequence <400> 2409 tgaggaccta gtacgtagta aaacacctgt tattgattta gcctttaata gtggactatt 60 tgagcacacg ggtaatgagg gtgaccttgt tgaattgaaa ctcttcacgg acggtattct 120 tctagcaaac agat 134 <210> 2410 <211> 134 <212> DNA <213> Artificial Sequence <400> 2410 gagttattat ggaatatggg cgccatcatg tttgaaaagg tttatccatt attaaaaccc 60 atactagaca cgatttttag tgcgttcggt agcattttca atcaggtaag cgagttctat 120 aatcagtatg gtaa 134 <210> 2411 <211> 134 <212> DNA <213> Artificial Sequence <400> 2411 tcttggttcc gctgtacaat gacacgtgac caaacgggta agaagttcac ttggaacttt 60 gagcatatcc aatcaaacaa cggaattaaa ccagttacaa aaaacccatt tacctacact 120 gcacctgtag caaa 134 <210> 2412 <211> 134 <212> DNA <213> Artificial Sequence <400> 2412 tggggactct ttgacgcagt aacggctaca ccaacagcag gagccactaa attaactaaa 60 acagcagtgt caacaatacg tcctgcatac ctatcaaatg gctacagtgc tttgcgcggt 120 acaacgtaca ctgt 134 <210> 2413 <211> 134 <212> DNA <213> Artificial Sequence <400> 2413 atctgtgtgc tagaagaata ccgtccgtga agagtttcaa ttcaacaagg tcaccctcat 60 tacccgtgtg ctcaaatagt ccactattaa aggctaaatc aataacaggt gttttactac 120 gtactagttc ctca 134 <210> 2414 <211> 134 <212> DNA <213> Artificial Sequence <400> 2414 gtatgtttta ccttttacaa agtttggcac tggttgaccc gtttggtatt tagttgcttt 60 ggcgcgtact tttactttac tacctacagg gaaatcacgt gtgtctgtga tttttggttt 120 agacggtggt ggtt 134 <210> 2415 <211> 134 <212> DNA <213> Artificial Sequence <400> 2415 cgtgaaacat taatacgtga gcctgtcatt ctagaaatct gactctcgtc tgtttcagga 60 taaccatagt aggcgcgtac ctcgttaggt ttaagatact caatgccttt ggctgtaccc 120 tcaaacattc gttt 134 <210> 2416 <211> 134 <212> DNA <213> Artificial Sequence <400> 2416 ggtgaggtat ttgtggtagg tactgtaaca attccattcc taaatgtaga acgcggatat 60 tatcaagtgg gtaattcaga cggtcagaac ctacaatata caagaatagg caataacacg 120 cttacttttg atgg 134 <210> 2417 <211> 134 <212> DNA <213> Artificial Sequence <400> 2417 tggggaatct ttgacgcagt aacggctaca ccaacagcag gagccactaa attaactaaa 60 acagcagtgt caacaatacg tcctgcatac ctatcaaatg gctacagtgc tttgcgcggt 120 acaacgtcca ctgt 134 <210> 2418 <211> 134 <212> DNA <213> Artificial Sequence <400> 2418 gtccatgtta ccttatccac tacctccctt gtggctactg agtctttata cttgagtagc 60 catctagatg atttaacaac ggaagctttg tttgctacag gtgcattgta ggtaaatggg 120 ttttttgtaa ctgg 134 <210> 2419 <211> 134 <212> DNA <213> Artificial Sequence <400> 2419 aatttattat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaatag tcta 134 <210> 2420 <211> 134 <212> DNA <213> Artificial Sequence <400> 2420 tgaggaccta gtacgtagta aaacacctgt tattgattta gcctttaata gtggactatt 60 tgagcacacg ggtaatgagg gtgaccttgt tgaattgaaa ctcttcacgg acggtattct 120 tctagcacac agat 134 <210> 2421 <211> 134 <212> DNA <213> Artificial Sequence <400> 2421 tggggactct ttgacgcagt aacggctaca ccaacagcag gagccactaa attaactaaa 60 acagcagtgt caacaatacg tcctgcatac ctatcaaatg gctacagtgc tttgcgcggt 120 acaacgtcca ctgt 134 <210> 2422 <211> 134 <212> DNA <213> Artificial Sequence <400> 2422 tagactcttc tgttagttga tgagtcgtta aacaacactc gcatgttccc gtttgaatat 60 tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga gaaatcataa 120 ttcaataata aatt 134 <210> 2423 <211> 133 <212> DNA <213> Artificial Sequence <400> 2423 agagaacgcg cgtaccatgt ttgaactttg gaaaacatta gaaggtaacg ccatgagtta 60 tgaccccatg acagggggaa taaaagaggt tgttgttaca gagaacattg aaacacaatc 120 taaaaaaggt aac 133 <210> 2424 <211> 133 <212> DNA <213> Artificial Sequence <400> 2424 gctggcaagt agttggttaa taagtcattg ctataataga ctattctgtt agttgatgag 60 tcgttaaaca acactcgcat gttcccgttt gaatattcta tagtcgcacc atttcctgtc 120 caaccattaa tag 133 <210> 2425 <211> 133 <212> DNA <213> Artificial Sequence <400> 2425 gttggttaat aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa 60 cactcgcatg ttcccgtttg aatattctat agtcgcacca tttcctgtcc aaccattaat 120 agtggggtct ttc 133 <210> 2426 <211> 133 <212> DNA <213> Artificial Sequence <400> 2426 cataacaaat accttgtacg tctaaattgt ttgtctcaat aaacgccaaa acccaattta 60 acatatcctc ccaatcacac tgaccgtcag gacgggacga aatttcacaa tacccctgtt 120 tggaatattg tct 133 <210> 2427 <211> 133 <212> DNA <213> Artificial Sequence <400> 2427 cccaatttaa catatcctcc caatcacact gaccgtcagg acgggacgaa atttcacaat 60 acccctgttt ggaatattgt ctatagggtg ttctatcgtt agcctctttc tgaacaatac 120 caccacccgt tgt 133 <210> 2428 <211> 133 <212> DNA <213> Artificial Sequence <400> 2428 agtaagtccc tcaggaatat cgtctaatga aagttgttca taattatata actcttgttc 60 ttcttgctcg cgctcaatac gctcctcttt tgttaaatga ctattatctt gtgcgctgat 120 tagttttcta ggt 133 <210> 2429 <211> 133 <212> DNA <213> Artificial Sequence <400> 2429 tcctggtccc catccacgcg tatagtcact ttcttttcta tttcttgctc ctgtaaacgc 60 attccctcag cgcgtacttt ctcatattgc tgtactgcct ccattaggtc taaaccgttg 120 tttgcatata cag 133 <210> 2430 <211> 133 <212> DNA <213> Artificial Sequence <400> 2430 tttagattga aattcactat ctactagcat gtttgtagat gtactttgtg tgtttctaaa 60 tgggtcactt aaaatagagt gtgccacacc ctcagggcat gaaaatgtta acgtcaacgg 120 tgtaatgtct aaa 133 <210> 2431 <211> 133 <212> DNA <213> Artificial Sequence <400> 2431 atctaaatcc tcaatctcat tcatttgtaa ctcacctttt tcaacctttt ccattttact 60 gtagtatgct aaaatctcgc gcattgttcg tacagttact ttctccgctg taaatgtttg 120 ttttttacct ttt 133 <210> 2432 <211> 133 <212> DNA <213> Artificial Sequence <400> 2432 tgtgtgtctc tttctcaatt aatactttct ctgtaggtgt caattcgttt tcaggtagtt 60 cgtacaagac tgccccaatt ggtaaaggtg tcgtctcgtt gtttactaac tcatatgttt 120 tcaaactaat tcc 133 <210> 2433 <211> 133 <212> DNA <213> Artificial Sequence <400> 2433 gttacctttt ttagattgtg tttcaatgtt ctctgtaaca acaacctctt ttattccccc 60 tgtcatgggg tcataactca tggcgttacc ttctaatgtt ttccaaagtt caaacatggt 120 acgcgcggtc tct 133 <210> 2434 <211> 133 <212> DNA <213> Artificial Sequence <400> 2434 attgagtgct ttattttggg tagttatact agcagaatac cgcacccagt tgtctgtact 60 tgtgtttgtg attgagactt ttccatcttc gcgcgtacta tcatagtagg taacacgcac 120 aattaattct gtt 133 <210> 2435 <211> 133 <212> DNA <213> Artificial Sequence <400> 2435 tgtgcagttt cttctgctgt taaaacgtgg ggtccttttc gtccccacat cgttacgttc 60 ttacctttag ggataaccgc ttgaccactt gggtcaataa ccatttcagc accacgtcca 120 tcattgacag tca 133 <210> 2436 <211> 133 <212> DNA <213> Artificial Sequence <400> 2436 taataaagat ggcgtctctc agtcccaaat taaatgccac agtttcttct agtaaaatat 60 tcatggtgac ctctcctctt tacccctcat gtctctcatt aacaacataa tcacagtcac 120 ttgcaaatag cgg 133 <210> 2437 <211> 133 <212> DNA <213> Artificial Sequence <400> 2437 tgtttgaccc ctctggtgta ccacctaatg ctcgtattgc tgtagttaac tcataaatgt 60 tacctgtagt tacgattgaa tctacgtcac gcccaacacg tagagtaata tctttctcgt 120 cccccatctc ctc 133 <210> 2438 <211> 133 <212> DNA <213> Artificial Sequence <400> 2438 taggtcgaga cgtctatgag ttagtaaaac gcggtgacct atcacagtgt tcgtttgggt 60 ttatggttaa aagtgatacg tggtcataca acgcaaacac agacacatat caccgcacaa 120 ttgaccaaat tgg 133 <210> 2439 <211> 133 <212> DNA <213> Artificial Sequence <400> 2439 ggaatgagtt tgaaaacata tgagttagta aacaacgaga cgacaccttt accaattggg 60 gcagtcttgt acgaactacc tgaaaacgaa ttgacaccta cagagaaagt attaattgag 120 aaagagaaac aca 133 <210> 2440 <211> 133 <212> DNA <213> Artificial Sequence <400> 2440 ttcatatagt gttattatac catttatgtg taaaacgttg ttatactagc tcatacgcaa 60 catcaaggtt acctaaatca tttttagcaa tcttaacaat aacaaactca tcctcaactt 120 catcctggtc ccc 133 <210> 2441 <211> 133 <212> DNA <213> Artificial Sequence <400> 2441 ttaacattaa ctaactgctc ttgtgattca tcaaaatgta atacccctgt gaactctata 60 atgtcatctg tttcatagtt gattatctca tggtcatctg acattttaat gagtcctgct 120 ccatctgtgg acg 133 <210> 2442 <211> 133 <212> DNA <213> Artificial Sequence <400> 2442 tcaatcagat agaagtgctg tttgttatag acccttcgtt tgtaggtacg ttttacgtaa 60 aaaactttaa actagaacaa aatgaccatg ctaccccgtt catccaacac attacagaac 120 gtggtaaact ata 133 <210> 2443 <211> 133 <212> DNA <213> Artificial Sequence <400> 2443 gttaatgaaa tggcgcagtt gggtaattat ctaatttata gacgacataa cggagatagt 60 gcctgtctta ctatcatgga cttcacacac aacccattgg cgggaacacg tgagataagt 120 tgtgaagatg gtg 133 <210> 2444 <211> 133 <212> DNA <213> Artificial Sequence <400> 2444 tgtatgtttt accttttaca aagtttggca ctggttgacc cggttggtat ttagttgctt 60 tggcgcgtac ttttacttta ctacctacag ggaaatcacg tgtgtctgtg atttttggtt 120 tagacggttg tgg 133 <210> 2445 <211> 133 <212> DNA <213> Artificial Sequence <400> 2445 ccaatgtggt caattgtgcg gtgatatgtg tctgtgtttg cgttgtatga ccacgtatca 60 cttttaacca taaacccaaa cgaacactgt gataggtcac cgcgttttac taactcatag 120 acgtctctac cta 133 <210> 2446 <211> 133 <212> DNA <213> Artificial Sequence <400> 2446 tactacgtca aaacggatgg cacccgctaa catttcaccg tagacattgt ggtcttgcca 60 acgtaccgtc atgtcagtac gtttgaacaa agtaatagct tgttctaagt caccaatgaa 120 taatagttta tca 133 <210> 2447 <211> 133 <212> DNA <213> Artificial Sequence <400> 2447 tcctcgacaa tgttcattgt tttacttttt aactgcatgt tttcaaactc aaagtcaatg 60 gtaaacttag cgcctccaaa gtctgaaata atactcctta gacgctccac tgctgttgtc 120 tcattatcat agt 133 <210> 2448 <211> 133 <212> DNA <213> Artificial Sequence <400> 2448 tctctgtttg ttgcttagtt ggtgtgaaaa tagtgttcat taatttcatc cccctcgttc 60 actagtatat aataaaaccc tcgcttatgc aagggttaat tttgtgagac atccataatg 120 tcaacagact gta 133 <210> 2449 <211> 133 <212> DNA <213> Artificial Sequence <400> 2449 ttctagctgt atatgcaaac aacggtttag acctaatgga ggcagtacag caatatgaga 60 aagtacgcgc tgagggaatg cgtttacagg agcaagaaat agaaaagaaa gtgactatac 120 gcgtggaggg gga 133 <210> 2450 <211> 133 <212> DNA <213> Artificial Sequence <400> 2450 tcttgagttg cctgactgta aatagcgtaa gtattacaat aaatgactag catgccagcg 60 tctagttttg aaattggtag ctgtttaagt tgtggaacaa ggtcctcgta aatcaaccac 120 ccttcctgag taa 133 <210> 2451 <211> 133 <212> DNA <213> Artificial Sequence <400> 2451 cataatagga gtcaaaggac ttgcctctgg ttttggtaat acaatcagtg gtatgtggac 60 aagtgtcaaa aactttttca ctacaggaac aagtaacgca tggaaccttg taaaaggttg 120 ggcgtcaaac att 133 <210> 2452 <211> 133 <212> DNA <213> Artificial Sequence <400> 2452 tcttatttca tatagtgtta ttataccatt tatgtgtaaa acgttgttat actagctcat 60 acgcaacatc aaggttacct aaatcatttt tagcaatctt aacaataaca aactcatcct 120 caacttcctc ctg 133 <210> 2453 <211> 133 <212> DNA <213> Artificial Sequence <400> 2453 tgtgtgtctc tttctcaatt aatactttct ctgtaggtgt caattcgttt tcaggtagtt 60 cgtacaagac tgccccaatt ggtaaaggtg tcgtctcgtt gtttactaac tcatatgttt 120 tcaaactcat tcc 133 <210> 2454 <211> 133 <212> DNA <213> Artificial Sequence <400> 2454 ccaatgtggt caattgtgcg gtgatatgtg tctgtgtttg cgttgtatga ccacgtatca 60 cttttaacca taaacccaaa cgaacactgt gataggtcac cgcgttttac taactcatag 120 acgtctcgac cta 133 <210> 2455 <211> 132 <212> DNA <213> Artificial Sequence <400> 2455 tccctcatta acatagtcac gttcaaaacg gtcatagtag aaccattcat caataccatc 60 aacctgcacg aaaaggctgc ctactccaac aatggtatat cgtttacctt tttccaatat 120 atcttctaca ca 132 <210> 2456 <211> 132 <212> DNA <213> Artificial Sequence <400> 2456 gttgatggta ttgatgaatg gttctactat gaccgttttg aacgtgacta tgttaatgag 60 ggaattgaat atagtttgaa agataaacat ggtgctacct tgagtgtcgc taggttatat 120 aaagataaaa ca 132 <210> 2457 <211> 132 <212> DNA <213> Artificial Sequence <400> 2457 gggaattgaa tatagtttga aagataaaca tggtgctacc ttgagtgtcg ctaggttata 60 taaagttaaa acagtgatta aaaatactga ttttactaat tatgtagtaa gcgtaaactt 120 aacagacgca ca 132 <210> 2458 <211> 132 <212> DNA <213> Artificial Sequence <400> 2458 tgtgacggaa tatttaactc ctgctggcaa gtagttggtt aataagtcat tgctataata 60 gactattctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt ttgaatattc 120 tatagtcgca cc 132 <210> 2459 <211> 132 <212> DNA <213> Artificial Sequence <400> 2459 ttaacgactc atcaactaac agaatagtct attatagcaa tgacttatta accaactact 60 tgccagcagg agttaaatat tccgtcacaa tagacgcatt cagcaacaat aatgggttaa 120 ttagggtagg ta 132 <210> 2460 <211> 132 <212> DNA <213> Artificial Sequence <400> 2460 tccttagtaa gtccctcagg aatatcgtct aatgaaagtt gttcataatt atataactct 60 tgttcttctt gctcgcgctc aatacgctcc tcttttgtta aatgactatt atcttgtgcg 120 ctgattagtt tt 132 <210> 2461 <211> 132 <212> DNA <213> Artificial Sequence <400> 2461 tcattagcgt ctgtcaaaat aaccaactca taacgtccgt tcttttctga cgtagtaccg 60 aagtctatcc gttcctcaaa tttaaaggct cctgttcgta aacctgttga tggtgctttg 120 acaggcggtg ta 132 <210> 2462 <211> 132 <212> DNA <213> Artificial Sequence <400> 2462 tgtgcgtctg ttaagtgtac gcttactaca tcattcgtaa aatcagtaat tttaatcact 60 gttttatctt tatataacct agcgacactc aaggtagcac catgtttatc tttcaaacta 120 tattcaagtc cc 132 <210> 2463 <211> 132 <212> DNA <213> Artificial Sequence <400> 2463 accaattaca gcaccgtcat agttagcctc taggagtaac aaatcaattt tcttacctgt 60 tttatcaagg tactcactga atgccacagt agtcattagg tctgtagcgt ataaaaaact 120 ttgaccgatt ga 132 <210> 2464 <211> 132 <212> DNA <213> Artificial Sequence <400> 2464 tcgtgtgcta acttggtaat gtcatcaagt agtttatcat attgcgcaaa ctcaatagat 60 ggtacatcac ctacgtaaat catcaactcg ttatccaata attacaccgt cctcatttac 120 tgctacaacc tc 132 <210> 2465 <211> 132 <212> DNA <213> Artificial Sequence <400> 2465 attctactag tagcttatag tctttcataa actcttcttt ggtattgtgc gattcaatca 60 attcaattgc cgcatatccc cacgagttcc atccgccacc tacgtcataa aagcccgcgt 120 ttgtgcgtgc tg 132 <210> 2466 <211> 132 <212> DNA <213> Artificial Sequence <400> 2466 tcaaacggtc aaagtttttt atacgctaca gacctaatga ctactgtggc attcagtgag 60 taccttgata aaacaggtaa gaaaattgat ttgttactcc tagaggctaa ctatgacggt 120 gctgtaagtg gt 132 <210> 2467 <211> 132 <212> DNA <213> Artificial Sequence <400> 2467 tgtgtagaag atatattgga aaaaggtaaa cgatatacca ttgttggagt aggcagcctt 60 ttcgtgcagg ttgatggtat tgatgaatgg ttctactatg accgttttga acgtgactat 120 gttaatgtgg ga 132 <210> 2468 <211> 132 <212> DNA <213> Artificial Sequence <400> 2468 taggtaaata tataattcgt tccatggtga acctcctcca attataactt ctttataaat 60 tataacacga aaaagacaac cctagttggg ttgcctcgtt cgtttattac agtccaaaac 120 caaactcacc gc 132 <210> 2469 <211> 132 <212> DNA <213> Artificial Sequence <400> 2469 tgtacgggaa ggtcctgacc atgcgtttgg tgcgaatgtt gtagcccact taggtttaaa 60 cgcctcagaa gggctgtagt cccatgaacc catgtagagg tttggtctag cagggtcgtt 120 agacgtattt gg 132 <210> 2470 <211> 132 <212> DNA <213> Artificial Sequence <400> 2470 gttctgacca tattgacccc tatccatact tgcgtaaatg gggaattagt aaagagcagt 60 ttgctaaaga cattaaaaat gggtttggtg gaaatagttc caatactgac aacaaaccta 120 aaccacaacc ac 132 <210> 2471 <211> 132 <212> DNA <213> Artificial Sequence <400> 2471 tagggtgttc atccttaggt tgctcgtcag ggttaacctc gtctgtttgt tcgtcttgtg 60 cctcacgaat ttccttgatt aatttatccg cctcatctaa tttaccttgt gcgataagtt 120 cacgggcttc ta 132 <210> 2472 <211> 132 <212> DNA <213> Artificial Sequence <400> 2472 tcgtttgcta acttggtaat gtcatcaagt agtttatcat attgcgcaaa ctcaatagat 60 ggtacatcac ctacgtaaat catcaactcg ttatccaata attacaccgt cctcatttac 120 tgctacaccc tc 132 <210> 2473 <211> 132 <212> DNA <213> Artificial Sequence <400> 2473 gactattctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt ttgaatattc 60 tatagtcgca ccatttcctg tccaaccatt aatagtgggg tctttcgaga aatcataatt 120 caatactcaa tt 132 <210> 2474 <211> 132 <212> DNA <213> Artificial Sequence <400> 2474 tcaatcggtc aaagtttttt atacgctaca gacctaatga ctactgtggc attcagtgag 60 taccttgata aaacaggtaa gaaaattgat ttgttactcc tagaggctaa ctatgacggt 120 gctgtaagtg gt 132 <210> 2475 <211> 132 <212> DNA <213> Artificial Sequence <400> 2475 gactcttctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt ttgaatattc 60 tatagtcgca ccatttcctg tccaaccatt aatagtgggg tctttcgaga aatcataatt 120 caatactcaa tt 132 <210> 2476 <211> 132 <212> DNA <213> Artificial Sequence <400> 2476 tcgtgtgcta acttggtaat gtcatcaagt agtttatcat attgcgcaaa ctcaatagat 60 ggtacatcac ctacgtaaat catcaactcg ttatccaata attacaccgt cctcatttac 120 tgctacaccc tc 132 <210> 2477 <211> 131 <212> DNA <213> Artificial Sequence <400> 2477 ctcctgctgg caagtagttg gttaataagt cattgctata atagactatt ctgttagttg 60 atgagtcgtt aaacaacact cgcatgttcc cgtttgaata ttctatagtc gcaccatttc 120 ctgtccaacc a 131 <210> 2478 <211> 131 <212> DNA <213> Artificial Sequence <400> 2478 tatttaactc ctgctggcaa gtagttggtt aataagtcat tgctataata gactattctg 60 ttagttgatg agtcgttaaa caacactcgc atgttcccgt ttgaatattc tatagtcgca 120 ccatttcctg t 131 <210> 2479 <211> 131 <212> DNA <213> Artificial Sequence <400> 2479 taataagtca ttgctataat agactattct gttagttgat gagtcgttaa acaacactcg 60 catgttcccg tttgaatatt ctatagtcgc accatttcct gtccaaccat taatagtggg 120 gtctttcgag a 131 <210> 2480 <211> 131 <212> DNA <213> Artificial Sequence <400> 2480 agtcattgct ataatagact attctgttag ttgatgagtc gttaaacaac actcgcatgt 60 tcccgtttga atattctata gtcgcaccat ttcctgtcca accattaata gtggggtctt 120 tcgagaaatc a 131 <210> 2481 <211> 131 <212> DNA <213> Artificial Sequence <400> 2481 ctattgtgac ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat 60 aatagactat tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat 120 attctatagt c 131 <210> 2482 <211> 131 <212> DNA <213> Artificial Sequence <400> 2482 gtgttgttta acgactcatc aactaacaga atagtctatt atagcaatga cttattaacc 60 aactacttgc cagcaggagt taaatattcc gtcacaatag acgcattcag caacaataat 120 gggttaatta g 131 <210> 2483 <211> 131 <212> DNA <213> Artificial Sequence <400> 2483 ttcgtcccgt cctgacggtc agtgtgattg ggaggatatg ttaaattggg ttttggcgtt 60 tattgagaca aacaatttag acgtacaagg tatttgttat gaccctgcac agtctcaatt 120 aattaccaca a 131 <210> 2484 <211> 131 <212> DNA <213> Artificial Sequence <400> 2484 catggacttc acacacaacc cattggcggg accacgtgag ataagttgtg aagatggtgc 60 acttgactta cttaataatg ttgtacctgc tattaaaacc acgtcacctc aatcgtttca 120 atactactgg a 131 <210> 2485 <211> 131 <212> DNA <213> Artificial Sequence <400> 2485 gtcaggacgg gacgaaattt cacaataccc ctgtttggaa tattgtctat agggtgttct 60 atcgttagcc tctttctgaa caataccacc acccgttgtt gctacccacg cgtgagagtc 120 aacaataaac a 131 <210> 2486 <211> 131 <212> DNA <213> Artificial Sequence <400> 2486 tttacaattc ctgactctag aatgtcaaac cccacagcgt gtgcgtgcag tacattgtaa 60 gcaaacatta gacgagcgtg tatcataatg tctaattctt taggctcgtc cataatgcgg 120 gcacgcactt c 131 <210> 2487 <211> 131 <212> DNA <213> Artificial Sequence <400> 2487 tatctccgcg gtgtgtttct accttccatt ctacattttt gaatgttggt tctgccaatt 60 tagggttttc tactaactca gctactgtgt tcattaccgc gttagttgtt tccaaaatag 120 ggtaagaacc t 131 <210> 2488 <211> 131 <212> DNA <213> Artificial Sequence <400> 2488 gaacttagct agtaactcag tcattactgc tttattgatt gtgttcaacc caatacgtgt 60 taagtggcga gcaatcaacg caactaagtc agggtcagag tcttgaattg cttcgttaga 120 cattggacta t 131 <210> 2489 <211> 131 <212> DNA <213> Artificial Sequence <400> 2489 ctctgtgttt ctctttctca attaatactt tctctgtagg tgtcaattcg ttttcaggta 60 gttcgtacaa gactgcccca attggtaaag gtgtcgtctc gttgtttact aactcatatg 120 ttttcaatct a 131 <210> 2490 <211> 131 <212> DNA <213> Artificial Sequence <400> 2490 ggaattgtag acgcgtctag tcctgtgcca attgaatacc acgtatatag tttaccacgt 60 tctgtaatgt gttggatgaa cggggtagca tggtcatttt gttctagttt aaagtttttt 120 acgtaaatcg t 131 <210> 2491 <211> 131 <212> DNA <213> Artificial Sequence <400> 2491 tcggtcaccc cgtaggctta accctcaacc ttatgaacct agtataaaca attaaactct 60 aatagtcaat taaaaaacca ttagagttta atgagaatat tctatttatc atcaagccac 120 atacacaatg c 131 <210> 2492 <211> 131 <212> DNA <213> Artificial Sequence <400> 2492 agagggctac tcaagtataa agactcagta gccacaaggg aggtagtgga taaggtaaca 60 tggacaatga aatctaagga agtcctacac attcgtgcag gttccaagac tagttacaag 120 tcatacggtc t 131 <210> 2493 <211> 131 <212> DNA <213> Artificial Sequence <400> 2493 ggacttgtag acgcgtctag tcctgtgcca attgaatacc acgtatatag tttaccacgt 60 tctgtaatgt gttggatgaa cggggtagca tggtcatttt gttctagttt aaagtttttt 120 acgtaaaacg t 131 <210> 2494 <211> 131 <212> DNA <213> Artificial Sequence <400> 2494 gccatgtact gagagcgtca aaattaccta ccctaattaa cccattattg ttgctgaatg 60 cgtctattgt gacggaatat ttaactcctg ctggcaagta gttggttaat aagtcattgc 120 tataatatac t 131 <210> 2495 <211> 131 <212> DNA <213> Artificial Sequence <400> 2495 tcgttcaccc cgtaggctta accctcaacc ttatgaacct agtataaaca attaaactct 60 aatagtcaat taaaaaacca ttagagttta atgagaatat tctatttatc atcaagccac 120 atacacactg c 131 <210> 2496 <211> 131 <212> DNA <213> Artificial Sequence <400> 2496 tgggtcatca gcgcgtttag gtttgcggtt gtccattgtc ctgtcatctg taaggctcgt 60 ttagcagttg cacgccaacg gtctacccct gaccctgttg ctgtggtgtc aattgctcca 120 ccttgtgact g 131 <210> 2497 <211> 131 <212> DNA <213> Artificial Sequence <400> 2497 tgtggtatta ttagaatata attagaaaag gaagtgttta taatgggtac aattattcta 60 ggtgttattt tggcaatttc attgatgtta aatgtgcgtt atagtgtaga gcgcaaatac 120 ttagtcgaca t 131 <210> 2498 <211> 131 <212> DNA <213> Artificial Sequence <400> 2498 gaactttcac aatacccctg tttggaatat tgtctatagg gtgttctatc gttagcctct 60 ttctgaacaa taccaccacc cgttgttgct acccacgcgt gagagtcaac aataaacaat 120 tctttttcag g 131 <210> 2499 <211> 131 <212> DNA <213> Artificial Sequence <400> 2499 gacctcaaag agctagaatc acgtaacaca tggcttacta gaacaaccgt aggagcaatt 60 atcactggtg tagtgggtgc aattttggca ttcatcactg gttaaatata tgatataata 120 gattagaaag g 131 <210> 2500 <211> 131 <212> DNA <213> Artificial Sequence <400> 2500 gacatcaaag agctagaatc acgtaacaca tggcttacta gaacaaccgt aggagcaatt 60 atcactggtg tagtgggtgc aattttggca ttcatcactg gttaaatata tgatataata 120 gattagacag g 131 <210> 2501 <211> 131 <212> DNA <213> Artificial Sequence <400> 2501 tctcgatgtt ttaacaacgg aagctttgtt tgctacaggt gcattgtagg taaatgggtt 60 ttttgtaact ggtttaattc cgttgtttga ttggatatgc tcaaagttcc aagtgaactt 120 cttacccgtt t 131 <210> 2502 <211> 131 <212> DNA <213> Artificial Sequence <400> 2502 cataatggag gcacaaagta agtcaattac tgagcttacg actgtcaaag gtggtacaaa 60 gtatgagaaa cgttaatacg aaacatgaac ggtttgaacc catggacgag ccttttgata 120 tgtacagcgt t 131 <210> 2503 <211> 131 <212> DNA <213> Artificial Sequence <400> 2503 ttcttctaaa acattgtcta actccgcgtc atgtaattct aatacctctg ctaattttgt 60 catattattt ttcctcctca tagtctaata cctcaatttg gttatcatat acccaccata 120 ggtgaccatc a 131 <210> 2504 <211> 131 <212> DNA <213> Artificial Sequence <400> 2504 ggacttgtag acgcgtctag tcctgtgcca attgaatacc acgtatatag tttaccacgt 60 tctgtaatgt gttggatgaa cggggtagca tggtcatttt gttctagttt aaagtttttt 120 acgtaaatcg t 131 <210> 2505 <211> 131 <212> DNA <213> Artificial Sequence <400> 2505 ccgactgtta gacccgcaaa agtgcccact aatgaggtga ccgcaccgat taccgcgcca 60 ccttttagag acattacacc atctaatagt ccacctaccc catctgtagc ctcgtctgct 120 ccacctttga t 131 <210> 2506 <211> 131 <212> DNA <213> Artificial Sequence <400> 2506 gacctcaaag agctagaatc acgtaacaca tggcttacta gaacaaccgt aggagcaatt 60 atcactggtg tagtgggtgc aattttggca ttcatcactg gttaaatata tgatataata 120 gattagacag g 131 <210> 2507 <211> 131 <212> DNA <213> Artificial Sequence <400> 2507 tggttcatca gcgcgtttag gtttgcggtt gtccattgtc ctgtcatctg taaggctcgt 60 ttagcagttg cacgccaacg gtctacccct gaccctgttg ctgtggtgtc aattgctcca 120 ccttgtgtct g 131 <210> 2508 <211> 131 <212> DNA <213> Artificial Sequence <400> 2508 tgggtcatca gcgcgtttag gtttgcggtt gtccattgtc ctgtcatctg taaggctcgt 60 ttagcagttg cacgccaacg gtctacccct gaccctgttg ctgtggtgtc aattgctcca 120 ccttgtgtct g 131 <210> 2509 <211> 131 <212> DNA <213> Artificial Sequence <400> 2509 tcggtcaccc cgtaggctta accctcaacc ttatgaacct agtataaaca attaaactct 60 aatagtcaat taaaaaacca ttagagttta atgagaatat tctatttatc atcaagccac 120 atacacactg c 131 <210> 2510 <211> 130 <212> DNA <213> Artificial Sequence <400> 2510 gaaaatagac atgaatttag atactacaaa attaggtgat ttagtggttg aaaaggcgcg 60 tgagttaaat gagaaaacgg gtattgagtc tgctgagtta cttgtcttca gtgctttagt 120 aactgtgact 130 <210> 2511 <211> 130 <212> DNA <213> Artificial Sequence <400> 2511 gaatatattg agtcaaaatt tgaactgaaa gaaaaggagg ctgtaaagga aacgggaatt 60 gtacacaaag ccaaaatgta cgtgcgtttg aaaattttcc caatggatgg ctctaacgcg 120 cgcgtaaacg 130 <210> 2512 <211> 130 <212> DNA <213> Artificial Sequence <400> 2512 cgttttgaac gtgactatgt taatgaggga attgaatata gtttgaaaga taaacatggt 60 gctaccttga gtgtcgctag gttatataaa gataaaacag tgattaaaat tactgatttt 120 acgaatgatg 130 <210> 2513 <211> 130 <212> DNA <213> Artificial Sequence <400> 2513 taacccttgc ataagcgagg gttttattat atactagtga acgaggggga tgaaattaat 60 gaacactatt ttcacaccaa ctaagcaaca aaaagagaac gcgcgtacca tgtttgaact 120 ttggaaaaca 130 <210> 2514 <211> 130 <212> DNA <213> Artificial Sequence <400> 2514 taactcctgc tggcaagtag ttggttaata agtcattgct ataatagact attctgttag 60 ttgatgagtc gttaaacaac actcgcatgt tcccgtttga atattctata gtcgcaccat 120 ttcctgtcca 130 <210> 2515 <211> 130 <212> DNA <213> Artificial Sequence <400> 2515 gaatatttaa ctcctgctgg caagtagttg gttaataagt cattgctata atagactatt 60 ctgttagttg atgagtcgtt aaacaacact cgcatgttcc cgtttgaata ttctatagtc 120 gcaccatttc 130 <210> 2516 <211> 130 <212> DNA <213> Artificial Sequence <400> 2516 tgtttaacga ctcatcaact aacagaatag tctattatag caatgactta ttaaccaact 60 acttgccagc aggagttaaa tattccgtca caatagacgc attcagcaac aataatgggt 120 taattagggt 130 <210> 2517 <211> 130 <212> DNA <213> Artificial Sequence <400> 2517 cccattattg ttgctgaatg cgtctattgt gacggaatat ttaactcctg ctggcaagta 60 gttggttaat aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa 120 cactcgcatg 130 <210> 2518 <211> 130 <212> DNA <213> Artificial Sequence <400> 2518 ttaacccatt attgttgctg aatgcgtcta ttgtgacgga atatttaact cctgctggca 60 agtagttggt taataagtca ttgctataat agactattct gttagttgat gagtcgttaa 120 acaacactcg 130 <210> 2519 <211> 130 <212> DNA <213> Artificial Sequence <400> 2519 attgttgctg aatgcgtcta ttgtgacgga atatttaact cctgctggca agtagttggt 60 taataagtca ttgctataat agactattct gttagttgat gagtcgttaa acaacactcg 120 catgttcccg 130 <210> 2520 <211> 130 <212> DNA <213> Artificial Sequence <400> 2520 gtagttggtt aataagtcat tgctataata gactattctg ttagttgatg agtcgttaaa 60 caacactcgc atgttcccgt ttgaatattc tatagtcgca ccatttcctg tccaaccatt 120 aatagtgggg 130 <210> 2521 <211> 130 <212> DNA <213> Artificial Sequence <400> 2521 gactcatcaa ctaacagaat agtctattat agcaatgact tattaaccaa ctacttgcca 60 gcaggagtta aatattccgt cacaatagac gcattcagca acaataatgg gttaattagg 120 gtaggtaatt 130 <210> 2522 <211> 130 <212> DNA <213> Artificial Sequence <400> 2522 tattccaaac aggggtattg tgaaatttcg tcccgtcctg acggtcagtg tgattgggag 60 gatatgttaa attgggtttt ggcgtttatt gagacaaaca atttagacgt acaaggtatt 120 tgttatgacc 130 <210> 2523 <211> 130 <212> DNA <213> Artificial Sequence <400> 2523 tccccgcttg cgtaacgttc tgaccagttt atttcctcga actcataaaa gtatgcttca 60 ctgtacgcgt ttataagcgc gtcaagaggg tcaatcttgt tgcggttaac ttgtttatca 120 atcataatta 130 <210> 2524 <211> 130 <212> DNA <213> Artificial Sequence <400> 2524 tgacatttta atgagtcctg ctccatctgt ggacgcaatt cctatagggt taaattccct 60 atcagtaaaa taaaattcta ttttaaaaac cccccttaca cttgtttctt tattaattat 120 accataataa 130 <210> 2525 <211> 130 <212> DNA <213> Artificial Sequence <400> 2525 tttttgtgtt ataatgatta gagatagaaa ggagaatgat tcactgaaaa ttgaaaaaca 60 aatgcgctca ggtttaccac aagtaggggt aagaccgtat ggacaaattc acgtacacag 120 tacggggaat 130 <210> 2526 <211> 130 <212> DNA <213> Artificial Sequence <400> 2526 gagtttggtt ttggactgta ataaacgaac gaggcaaccc aactagggtt gtctttttcg 60 tgttataatt tataaagaag ttataattgg aggaggttca ccatggaacg aattatatat 120 ttacctatga 130 <210> 2527 <211> 130 <212> DNA <213> Artificial Sequence <400> 2527 ctcttctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt gaatattcta 60 tagtcgcacc atttcctgtc caaccattaa tagtggggtc tttcgagaaa tcataattca 120 atactaactt 130 <210> 2528 <211> 130 <212> DNA <213> Artificial Sequence <400> 2528 ctattctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt gaatattcta 60 tagtcgcacc atttcctgtc caaccattaa tagtggggtc tttcgagaaa tcataattca 120 atactaactt 130 <210> 2529 <211> 129 <212> DNA <213> Artificial Sequence <400> 2529 aacgatatac cattgttgga gtaggcagcc ttttcgtgca ggttgatggt attgatgaat 60 ggttctacta tgaccgtttt gaacgtgact atgttaatga gggaattgaa tatagtttga 120 aagataaac 129 <210> 2530 <211> 129 <212> DNA <213> Artificial Sequence <400> 2530 aaagagaacg cgcgtaccat gtttgaactt tggaaaacat tagaaggtaa cgccatgagt 60 tatgacccca tgacaggggg aataaaagag gttgttgtta cagagaacat tgaaacacaa 120 tctaaaaaa 129 <210> 2531 <211> 129 <212> DNA <213> Artificial Sequence <400> 2531 aatagactat tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat 60 attctatagt cgcaccattt cctgtccaac cattaatagt ggggtctttc gagaaatcat 120 aattcaata 129 <210> 2532 <211> 129 <212> DNA <213> Artificial Sequence <400> 2532 tagactattc tgttagttga tgagtcgtta aacaacactc gcatgttccc gtttgaatat 60 tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga gaaatcataa 120 ttcaatact 129 <210> 2533 <211> 129 <212> DNA <213> Artificial Sequence <400> 2533 tataatagac tattctgtta gttgatgagt cgttaaacaa cactcgcatg ttcccgtttg 60 aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct ttcgagaaat 120 cataattca 129 <210> 2534 <211> 129 <212> DNA <213> Artificial Sequence <400> 2534 gctataatag actattctgt tagttgatga gtcgttaaac aacactcgca tgttcccgtt 60 tgaatattct atagtcgcac catttcctgt ccaaccatta atagtggggt ctttcgagaa 120 atcataatt 129 <210> 2535 <211> 129 <212> DNA <213> Artificial Sequence <400> 2535 attgctataa tagactattc tgttagttga tgagtcgtta aacaacactc gcatgttccc 60 gtttgaatat tctatagtcg caccatttcc tgtccaacca ttaatagtgg ggtctttcga 120 gaaatcata 129 <210> 2536 <211> 129 <212> DNA <213> Artificial Sequence <400> 2536 gtctattgtg acggaatatt taactcctgc tggcaagtag ttggttaata agtcattgct 60 ataatagact attctgttag ttgatgagtc gttaaacaac actcgcatgt tcccgtttga 120 atattctat 129 <210> 2537 <211> 129 <212> DNA <213> Artificial Sequence <400> 2537 gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa taagtcattg 60 ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt 120 gaatattct 129 <210> 2538 <211> 129 <212> DNA <213> Artificial Sequence <400> 2538 acgaaatttc acaatacccc tgtttggaat attgtctata gggtgttcta tcgttagcct 60 ctttctgaac aataccacca cccgttgttg ctacccacgc gtgagagtca acaataaaca 120 attcttttt 129 <210> 2539 <211> 129 <212> DNA <213> Artificial Sequence <400> 2539 gtaaaaggta aaaaacaaac atttacagcg gagaaagtaa ctgtacgaac aatgcgcgag 60 attttagcat actacagtaa aatggaaaag gttgaaaaag gtgagttaca aatgaatgag 120 attgaggat 129 <210> 2540 <211> 129 <212> DNA <213> Artificial Sequence <400> 2540 gaatttcctt gattaattta tccgcctcat ctaatttacc ttgtgcgata agttcacggg 60 cttctagtaa tcgtttatcc atgtttcaca ctccttatta tgtttcttaa ataattataa 120 cacgcgtgt 129 <210> 2541 <211> 129 <212> DNA <213> Artificial Sequence <400> 2541 tgtcctccta atgttttaat acatttatta gtttatcaaa accccaacca gttgtcaagc 60 attattttta aatttcttgt aaatgttcgt acggaatgag ctgacgtata ccatcaatcg 120 ttctacatg 129 <210> 2542 <211> 129 <212> DNA <213> Artificial Sequence <400> 2542 tatgttagta tagacgagtt tattgaaaag gctagagagg acttatagga ggtaactgct 60 tatgaaactt gtaaatatga ctaagaaaac tatacctaca gaagataact tactccattc 120 aatatgggt 129 <210> 2543 <211> 129 <212> DNA <213> Artificial Sequence <400> 2543 acccacaacc gtctaaacca aaaatcacag acacacgtga tttccctgta ggtagtaaag 60 taaaagtacg cgccaaagca actaaatacc aaacgggtca accagtgcca aactttgtaa 120 aaggtaaaa 129 <210> 2544 <211> 129 <212> DNA <213> Artificial Sequence <400> 2544 gtgttttgta ggtaatatcc actgacccat cctgaggcag gtattttctt acctgagttc 60 ttagttacat aataccattg gttgttttta ataatctttt gacccgtttg acgtttggtt 120 gtttcaatc 129 <210> 2545 <211> 129 <212> DNA <213> Artificial Sequence <400> 2545 gatagagctt tacctgatag atacaattca tctttttcat ctacaatgtt tatcctatcg 60 cctacattta aatcagaagg tacattgact acgtttactt cataattaaa agcaggttga 120 cttttcttt 129 <210> 2546 <211> 129 <212> DNA <213> Artificial Sequence <400> 2546 ccgcaagtga agccaattta cctttatcaa gggtgtcata cgttacagca cgtgtgaaca 60 aacctcctgt tgttgataag agtctggacc atttaggagc ttcttgcgtg tcaatcataa 120 ccccattct 129 <210> 2547 <211> 129 <212> DNA <213> Artificial Sequence <400> 2547 tgtactacgt taagcgcgta tagtgctaat tcagtaggtg agtcaccgtc aattaataca 60 gtatcaataa cattagtcac agttactaaa gcactgaaga caagtaactc agcagactca 120 atacccggt 129 <210> 2548 <211> 129 <212> DNA <213> Artificial Sequence <400> 2548 ttagagaggg ctatgaggct cctacgtggc ttacgtttga tatgttcaaa accatgcacc 60 cacatttagc caatgtgaat gtaactcagt caaaaataac tgagtccctt acctcattct 120 ttgaacgat 129 <210> 2549 <211> 129 <212> DNA <213> Artificial Sequence <400> 2549 attgaccgct gtagcgcaga cgataccgtc acattaacat taggtgattt tcgtattcaa 60 tattcaggta ttgaccctca gttgctacag atagcgtcag atttttcaaa acagtttgac 120 aacagtagt 129 <210> 2550 <211> 129 <212> DNA <213> Artificial Sequence <400> 2550 taatgagaca acagcagtgg agcgtctaag gagtattatt tcagactttg gaggcgctaa 60 gtttaccatt gactttgagt ttgaaaacat gcagttaaaa agtaaaacaa tgaacattgt 120 agaggatct 129 <210> 2551 <211> 129 <212> DNA <213> Artificial Sequence <400> 2551 tttgacgttt ggttgtttca aacgtgacgc ccttaggtaa cagaccgtat gacttgtaac 60 tagtcttgga acctgcacga atgtgtagga cttccttaga tttcattgtc catgttacct 120 tatccacga 129 <210> 2552 <211> 129 <212> DNA <213> Artificial Sequence <400> 2552 tcatgagaca acagcagtgg agcgtctaag gagtattatt tcagactttg gaggcgctaa 60 gtttaccatt gactttgagt ttgaaaacat gcagttaaaa agtaaaacaa tgaacattgt 120 agaggatat 129 <210> 2553 <211> 129 <212> DNA <213> Artificial Sequence <400> 2553 tgtggtttag gtttgttgtc agtattggaa ctatttccac caaacccatt tttaatgtct 60 ttagcaaact gctctttact aattccccat ttacgcaagt atggataggg gtcaatatgg 120 tcagaacca 129 <210> 2554 <211> 129 <212> DNA <213> Artificial Sequence <400> 2554 ccataataat gttgaaagca agtttttcct catctacttt tttaccgtat ttcaacttat 60 caaaatcaaa ctttagttcc tgtaagacgt tctcaaacgc tttgtgtgtt tcttctttat 120 tcatctgat 129 <210> 2555 <211> 129 <212> DNA <213> Artificial Sequence <400> 2555 gttagagctt tacctgatag atacaattca tctttttcat ctacaatgtt tatcctatcg 60 cctacattta aatcagaagg tacattgact acgtttactt cataattaaa agcaggttga 120 cttttctat 129 <210> 2556 <211> 129 <212> DNA <213> Artificial Sequence <400> 2556 agtgaccgct gtagcgcaga cgataccgtc acattaacat taggtgattt tcgtattcaa 60 tattcaggta ttgaccctca gttgctacag atagcgtcag atttttcaaa acagtttgac 120 aacagtatt 129 <210> 2557 <211> 129 <212> DNA <213> Artificial Sequence <400> 2557 tcttaaccgc gggtgagtta gctgtatcac attaattcta aaatgtcaag ttctaattct 60 aattttcttt tttgttcttt aaacgctttt tgtgaccgtt gtgccactgc tacagttgta 120 tcatcatat 129 <210> 2558 <211> 129 <212> DNA <213> Artificial Sequence <400> 2558 tagtggataa ggtaacatgg acaatgaaat ctaaggaagt cctacacatt cgtgcaggtt 60 ccaagactag ttacaagtca tacggtctgt tacctaaggg cgtcacgttt gaaacaacca 120 aacgtcaca 129 <210> 2559 <211> 129 <212> DNA <213> Artificial Sequence <400> 2559 acaaagaatt gtttattgtt gactctcacg cgtgggtagc aacaacgggt ggtggtattg 60 ttcagaaaga ggctaacgat agaacaccct atagacaata ttccaaacag gggtattgtg 120 aaatttctt 129 <210> 2560 <211> 129 <212> DNA <213> Artificial Sequence <400> 2560 tattctgtta gttgatgagt cgttaaacaa cactcgcatg ttcccgtttg aatattctat 60 agtcgcacca tttcctgtcc aaccattaat agtggggtct ttcgagaaat cataattcaa 120 tactaaagt 129 <210> 2561 <211> 129 <212> DNA <213> Artificial Sequence <400> 2561 gtttgaaaca accaaacgtc aaacgggtca aaagattatt aaaaacaacc aatggtatta 60 tgtaactaag aactcaggta agaaaatacc tgcctcagga tgggtcagtg gatattacct 120 acaaaaccc 129 <210> 2562 <211> 129 <212> DNA <213> Artificial Sequence <400> 2562 ttgacttgtt caaagactcc ctgtactaat ggtaataagt cctcaaaggc tacgttatcc 60 actaacatat cataagtaag ttttgtgttt gagaaaatgg agagaactaa gtttagcata 120 tcatctata 129 <210> 2563 <211> 129 <212> DNA <213> Artificial Sequence <400> 2563 tcttctgtta gttgatgagt cgttaaacaa cactcgcatg ttcccgtttg aatattctat 60 agtcgcacca tttcctgtcc aaccattaat agtggggtct ttcgagaaat cataattcaa 120 tactaaagt 129 <210> 2564 <211> 129 <212> DNA <213> Artificial Sequence <400> 2564 tgatagatac aattcatctt tttcatctac aatgtttatc ctatcgccta catttaaatc 60 agaaggtaca ttgactacgt ttacttcata attaaaagca ggttgacttt tctttttcaa 120 ttcactacc 129 <210> 2565 <211> 129 <212> DNA <213> Artificial Sequence <400> 2565 gatagagctt tacctgatag atacaattca tctttttcat ctacaatgtt tatcctatcg 60 cctacattta aatcagaagg tacattgact acgtttactt cataattaaa agcaggttga 120 cttttctat 129 <210> 2566 <211> 129 <212> DNA <213> Artificial Sequence <400> 2566 acgaaatttc acaatacccc tgtttggaat attgtctata gggtgttcta tcgttagcct 60 ctttctgaac aataccacca cccgttgttg ctacccacgc gtgagagtca acaataaaca 120 attctttgt 129 <210> 2567 <211> 129 <212> DNA <213> Artificial Sequence <400> 2567 gggttttgta ggtaatatcc actgacccat cctgaggcag gtattttctt acctgagttc 60 ttagttacat aataccattg gttgttttta ataatctttt gacccgtttg acgtttggtt 120 gtttcaatc 129 <210> 2568 <211> 129 <212> DNA <213> Artificial Sequence <400> 2568 tgtgacgttt ggttgtttca aacgtgacgc ccttaggtaa cagaccgtat gacttgtaac 60 tagtcttgga acctgcacga atgtgtagga cttccttaga tttcattgtc catgttacct 120 tatccacga 129 <210> 2569 <211> 129 <212> DNA <213> Artificial Sequence <400> 2569 tgtctcattt aactcacgcg ccttttcaac cactaaatca cctaattttg tagtatctaa 60 attcatgtct atgttcctcc cttatttggt tgaaacaacc atttagaaaa cattagtgac 120 aaccctata 129 <210> 2570 <211> 129 <212> DNA <213> Artificial Sequence <400> 2570 agtgaccgct gtagcgcaga cgataccgtc acattaacat taggtgattt tcgtattcaa 60 tattcaggta ttgaccctca gttgctacag atagcgtcag atttttcaaa acagtttgac 120 aacagtagt 129 <210> 2571 <211> 129 <212> DNA <213> Artificial Sequence <400> 2571 tcatgagaca acagcagtgg agcgtctaag gagtattatt tcagactttg gaggcgctaa 60 gtttaccatt gactttgagt ttgaaaacat gcagttaaaa agtaaaacaa tgaacattgt 120 agaggatct 129 <210> 2572 <211> 128 <212> DNA <213> Artificial Sequence <400> 2572 aatagacatg aatttagata ctacaaaatt aggtgattta gtggttgaaa aggcgcgtga 60 gttaaatgag aaaacgggta ttgagtctgc tgagttactt gtcttcagtg ctttagtaac 120 tgtgacta 128 <210> 2573 <211> 128 <212> DNA <213> Artificial Sequence <400> 2573 tatagggttg tcactaatgt tttctaaatg gttgtttcaa ccaaataagg gaggaaaata 60 gacatgaatt tagatactac aaaattaggt gatttagtgg ttgaaaaggc gcgtgagtta 120 aatgagaa 128 <210> 2574 <211> 128 <212> DNA <213> Artificial Sequence <400> 2574 atagggttgt cactaatgtt ttctaaatgg ttgtttcaac caaataaggg aggaaaatag 60 acatgaattt agatactaca aaattaggtg atttagtggt tgaaaaggcg cgtgagttaa 120 atgagaaa 128 <210> 2575 <211> 128 <212> DNA <213> Artificial Sequence <400> 2575 tatgtatttt atttttgacc atgaggaata tattgagtca aaatttgaac tgaaagaaaa 60 ggaggctgta aaggaaacgg gaattgtaca caaagccaaa atgtacgtgc gtttgaaaat 120 tttcccaa 128 <210> 2576 <211> 128 <212> DNA <213> Artificial Sequence <400> 2576 taatagacta ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa 60 tattctatag tcgcaccatt tcctgtccaa ccattaatag tggggtcttt cgagaaatca 120 taattcaa 128 <210> 2577 <211> 128 <212> DNA <213> Artificial Sequence <400> 2577 gactattctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt ttgaatattc 60 tatagtcgca ccatttcctg tccaaccatt aatagtgggg tctttcgaga aatcataatt 120 caatacta 128 <210> 2578 <211> 128 <212> DNA <213> Artificial Sequence <400> 2578 actattctgt tagttgatga gtcgttaaac aacactcgca tgttcccgtt tgaatattct 60 atagtcgcac catttcctgt ccaaccatta atagtggggt ctttcgagaa atcataattc 120 aatactaa 128 <210> 2579 <211> 128 <212> DNA <213> Artificial Sequence <400> 2579 attctgttag ttgatgagtc gttaaacaac actcgcatgt tcccgtttga atattctata 60 gtcgcaccat ttcctgtcca accattaata gtggggtctt tcgagaaatc ataattcaat 120 actaaatt 128 <210> 2580 <211> 128 <212> DNA <213> Artificial Sequence <400> 2580 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 60 gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg gggggggggg 120 gggggggg 128 <210> 2581 <211> 128 <212> DNA <213> Artificial Sequence <400> 2581 ctattctgtt agttgatgag tcgttaaaca acactcgcat gttcccgttt gaatattcta 60 tagtcgcacc atttcctgtc caaccattaa tagtggggtc tttcgagaaa tcataattca 120 atactaaa 128 <210> 2582 <211> 128 <212> DNA <213> Artificial Sequence <400> 2582 tattctgtta gttgatgagt cgttaaacaa cactcgcatg ttcccgtttg aatattctat 60 agtcgcacca tttcctgtcc aaccattaat agtggggtct ttcgagaaat cataattcaa 120 tactaaat 128 <210> 2583 <211> 128 <212> DNA <213> Artificial Sequence <400> 2583 tgctggcaag tagttggtta ataagtcatt gctataatag actattctgt tagttgatga 60 gtcgttaaac aacactcgca tgttcccgtt tgaatattct atagtcgcac catttcctgt 120 ccaaccat 128 <210> 2584 <211> 128 <212> DNA <213> Artificial Sequence <400> 2584 tgctataata gactattctg ttagttgatg agtcgttaaa caacactcgc atgttcccgt 60 ttgaatattc tatagtcgca ccatttcctg tccaaccatt aatagtgggg tctttcgaga 120 aatcataa 128 <210> 2585 <211> 128 <212> DNA <213> Artificial Sequence <400> 2585 tagtctatta tagcaatgac ttattaacca actacttgcc agcaggagtt aaatattccg 60 tcacaataga cgcattcagc aacaataatg ggttaattag ggtaggtaat tttgacgctc 120 tcagtaca 128 <210> 2586 <211> 128 <212> DNA <213> Artificial Sequence <400> 2586 aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa cactcgcatg 60 ttcccgtttg aatattctat agtcgcacca tttcctgtcc aaccattaat agtggggtct 120 ttcgagaa 128 <210> 2587 <211> 128 <212> DNA <213> Artificial Sequence <400> 2587 tgcgtctatt gtgacggaat atttaactcc tgctggcaag tagttggtta ataagtcatt 60 gctataatag actattctgt tagttgatga gtcgttaaac aacactcgca tgttcccgtt 120 tgaatatt 128 <210> 2588 <211> 128 <212> DNA <213> Artificial Sequence <400> 2588 cggaatattt aactcctgct ggcaagtagt tggttaataa gtcattgcta taatagacta 60 ttctgttagt tgatgagtcg ttaaacaaca ctcgcatgtt cccgtttgaa tattctatag 120 tcgcacca 128 <210> 2589 <211> 128 <212> DNA <213> Artificial Sequence <400> 2589 ggaatattta actcctgctg gcaagtagtt ggttaataag tcattgctat aatagactat 60 tctgttagtt gatgagtcgt taaacaacac tcgcatgttc ccgtttgaat attctatagt 120 cgcaccat 128 <210> 2590 <211> 128 <212> DNA <213> Artificial Sequence <400> 2590 acccattatt gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt 60 agttggttaa taagtcattg ctataataga ctattctgtt agttgatgag tcgttaaaca 120 acactcgc 128 <210> 2591 <211> 128 <212> DNA <213> Artificial Sequence <400> 2591 gttgctgaat gcgtctattg tgacggaata tttaactcct gctggcaagt agttggttaa 60 taagtcattg ctataataga ctattctgtt agttgatgag tcgttaaaca acactcgcat 120 gttcccgt 128 <210> 2592 <211> 128 <212> DNA <213> Artificial Sequence <400> 2592 tattgttgct gaatgcgtct attgtgacgg aatatttaac tcctgctggc aagtagttgg 60 ttaataagtc attgctataa tagactattc tgttagttga tgagtcgtta aacaacactc 120 gcatgttc 128 <210> 2593 <211> 128 <212> DNA <213> Artificial Sequence <400> 2593 ttgctgaatg cgtctattgt gacggaatat ttaactcctg ctggcaagta gttggttaat 60 aagtcattgc tataatagac tattctgtta gttgatgagt cgttaaacaa cactcgcatg 120 ttcccgtt 128 <210> 2594 <211> 128 <212> DNA <213> Artificial Sequence <400> 2594 ttattgttgc tgaatgcgtc tattgtgacg gaatatttaa ctcctgctgg caagtagttg 60 gttaataagt cattgctata atagactatt ctgttagttg atgagtcgtt aaacaacact 120 cgcatgtt 128 <210> 2595 <211> 128 <212> DNA <213> Artificial Sequence <400> 2595 tcatcaacta acagaatagt ctattatagc aatgacttat taaccaacta cttgccagca 60 ggagttaaat attccgtcac aatagacgca ttcagcaaca ataatgggtt aattagggta 120 ggtaattt 128 <210> 2596 <211> 128 <212> DNA <213> Artificial Sequence <400> 2596 attattgttg ctgaatgcgt ctattgtgac ggaatattta actcctgctg gcaagtagtt 60 ggttaataag tcattgctat aatagactat tctgttagtt gatgagtcgt taaacaacac 120 tcgcatgt 128 <210> 2597 <211> 128 <212> DNA <213> Artificial Sequence <400> 2597 aagtagttgg ttaataagtc attgctataa tagactattc tgttagttga tgagtcgtta 60 aacaacactc gcatgttccc gtttgaatat tctatagtcg caccatttcc tgtccaacca 120 ttaatagt 128 <210> 2598 <211> 128 <212> DNA <213> Artificial Sequence <400> 2598 agtagttggt taataagtca ttgctataat agactattct gttagttgat gagtcgttaa 60 acaacactcg catgttcccg tttgaatatt ctatagtcgc accatttcct gtccaaccat 120 taatagtg 128 <210> 2599 <211> 128 <212> DNA <213> Artificial Sequence <400> 2599 tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt 60 tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt 120 tttttttt 128 <210> 2600 <211> 128 <212> DNA <213> Artificial Sequence <400> 2600 tattgttgac tctcacgcgt gggtagcaac aacgggtggt ggtattgttc agaaagaggc 60 taacgataga acaccctata gacaatattc caaacagggg tattgtgaaa tttcgtcccg 120 tcctgacg 128 <210> 2601 <211> 128 <212> DNA <213> Artificial Sequence <400> 2601 cctcagtggc gcgctttggt caggatggta ttagtgtgac tggtactcaa tcagagtatg 60 tacaaacaac tagttctgta gaacctacct caggatggag tacaacacgt ccaacacctc 120 aaattggt 128 <210> 2602 <211> 128 <212> DNA <213> Artificial Sequence <400> 2602 gtggtttttg caaaaagtac cactattgta taaaattagt aggtatgtaa atactcgtat 60 agcaataaaa cgcattgaaa acaggggggg agaacgaaat gggctacttt aagaatttgt 120 tattagcg 128 <210> 2603 <211> 128 <212> DNA <213> Artificial Sequence <400> 2603 gtgcgtcaga gtcacggatg gctatagaca ttaatatgtc attagcgtct gtcaaaataa 60 ccaactcata acgtccgttc ttttctgacg tagtaccgaa gtctatccgt tcctcaaatt 120 taaaggct 128 <210> 2604 <211> 128 <212> DNA <213> Artificial Sequence <400> 2604 gtccgtctgt tagacccgca aaagtgccca ctaatgaggt gaccgcaccg attaccgcgc 60 caccttttag agacattaca ccatctaata gtccacctac cccatctgta gcctcgtctg 120 ctccacct 128 <210> 2605 <211> 128 <212> DNA <213> Artificial Sequence <400> 2605 cgcggtaaga gggtaggact agcagacttt cagaagttca ttattggtat gatattttca 60 tgggttaaaa aggactcagg gtacaggcga tttactaaag tggtaatctc catgagtcgt 120 aagaacgg 128 <210> 2606 <211> 128 <212> DNA <213> Artificial Sequence <400> 2606 attgtcaact agtaacgcac tattaaactc accttttgtg ttaaatgcgc ggttagatgg 60 gagttctgtg tacatttttc caaacaatgg tgagcctatg attttggtca ttagaataga 120 ctttccat 128 <210> 2607 <211> 128 <212> DNA <213> Artificial Sequence <400> 2607 taggcaatga agtgattgtt gaatactggt acggtaacaa gttactaaaa tctatcaaga 60 cagacgtaac taagtacaaa tcatcttggt tccgctgtac aatgacacgt gaccaaacgg 120 gtaagaag 128 <210> 2608 <211> 128 <212> DNA <213> Artificial Sequence <400> 2608 tttgtcaact agtaacgcac tattaaactc accttttgtg ttaaatgcgc ggttagatgg 60 gagttctgtg tacatttttc caaacaatgg tgagcctatg attttggtca ttagaataga 120 ctttccag 128 <210> 2609 <211> 128 <212> DNA <213> Artificial Sequence <400> 2609 ttctatagtc ccatggttca aacggacgta gttctaatgt acgcatgttt agcgcaccgt 60 tttgaaaata cgcacattca ccaaggtatc tgtacttatc gttcgttcta tcgttgaaat 120 atccctca 128 <210> 2610 <211> 128 <212> DNA <213> Artificial Sequence <400> 2610 tactatattc ctgtagatgg ctcaaccggt aatggtgtga aatctatcgc tgttacttac 60 gctgtaggta cctcaggtac aacagcacca tccacaggtt ggcaagcaac accaccaaat 120 gtaacagg 128 <210> 2611 <211> 128 <212> DNA <213> Artificial Sequence <400> 2611 taatttagta ttgaattatg atttctcgaa agaccccact attaatggtt ggacaggaaa 60 tggtgcgact atagaatatt caaacgggaa catgcgagtg ttgtttaacg actcatcaac 120 taacagac 128 <210> 2612 <211> 128 <212> DNA <213> Artificial Sequence <400> 2612 ttattgttgg aaagacgtag acgccactga gctacgcttc tatggttgtg ttgatgggtt 60 acttgctaaa gcgtttattt gtgccatgtt caaccttgat aaacaagcat ttaaccaaac 120 aaacgctc 128 <210> 2613 <211> 128 <212> DNA <213> Artificial Sequence <400> 2613 cccaatttga ggtgttggac gtgttgtact ccatcctgag gtaggttcta cagaactagt 60 tgtttgtaca tactctgatt gagtaccagt cacactaata ccatcctgac caaagcgcgc 120 cactgagt 128 <210> 2614 <211> 128 <212> DNA <213> Artificial Sequence <400> 2614 tctgatggta caacatcagt agcctataca gtgaactata ttcctgtaga tggctcaacc 60 ggtaatggtg tgaaatctat cgctgttact tacgctgtag gtacctcagg tacaacagca 120 ccatccac 128 <210> 2615 <211> 128 <212> DNA <213> Artificial Sequence <400> 2615 ttccgtctgt tagacccgca aaagtgccca ctaatgaggt gaccgcaccg attaccgcgc 60 caccttttag agacattaca ccatctaata gtccacctac cccatctgta gcctcgtctg 120 ctccacca 128 <210> 2616 <211> 128 <212> DNA <213> Artificial Sequence <400> 2616 taacttcata atgagaaaag agttgaaaaa acacattaag cagatgaacc cacaagagat 60 tgtaactgtt gtgaatatgg ttgagagcgc tacaagagga atgtgtaaag agacaattag 120 gactagtt 128 <210> 2617 <211> 128 <212> DNA <213> Artificial Sequence <400> 2617 gtaaattgag ggttaccttt gacaagttcg tataccttgt ccccaacttt acctaagaac 60 gtacctactt tattatcact atcaccactt ttaaactctt gcgcttgtgg gtaaatgaca 120 gagtatag 128 <210> 2618 <211> 128 <212> DNA <213> Artificial Sequence <400> 2618 atggaggagg tttttgacgt ttacttacaa cctgaggagg tattttaatg tttaaggttg 60 aacatgttag attaacagaa tataatgacg cctatatgag tgtactgttg tttaggcaga 120 aagtacgt 128 <210> 2619 <211> 128 <212> DNA <213> Artificial Sequence <400> 2619 atagaaacta tttttcactt gatagacacg ggacacatta gcacgtataa attgccaaaa 60 ttaccagaga ataaaacata tgacttattt gaggaggatg aatagaatgg aactaacatt 120 acatgatt 128 <210> 2620 <211> 128 <212> DNA <213> Artificial Sequence <400> 2620 tagcgtttgt ttggttaaat gcttgtttat caaggttgaa catggcacaa ataaacgctt 60 tagcaagtaa cccatcaaca caaccataga agcgtagctc agtggcgtct acgtctttcc 120 aacaatac 128 <210> 2621 <211> 128 <212> DNA <213> Artificial Sequence <400> 2621 cttctgttag ttgatgagtc gttaaacaac actcgcatgt tcccgtttga atattctata 60 gtcgcaccat ttcctgtcca accattaata gtggggtctt tcgagaaatc ataattcaat 120 actaaatg 128 <210> 2622 <211> 128 <212> DNA <213> Artificial Sequence <400> 2622 tggtggagca gacgaggcta cagatggggt aggtggacta ttagatggtg taatgtctct 60 aaaaggtggc gcggtaatcg gtgcggtcac ctcattagtg ggcacttttg cgggtctaac 120 agacggac 128 <210> 2623 <211> 128 <212> DNA <213> Artificial Sequence <400> 2623 catttagtat tgaattatga tttctcgaaa gaccccacta ttaatggttg gacaggaaat 60 ggtgcgacta tagaatattc aaacgggaac atgcgagtgt tgtttaacga ctcatcaact 120 aacagaat 128 <210> 2624 <211> 128 <212> DNA <213> Artificial Sequence <400> 2624 ctggaaagtc tattctaatg accaaaatca taggctcacc attgtttgga aaaatgtaca 60 cagaactccc atctaaccgc gcatttaaca caaaaggtga gtttaatagt gcgttactag 120 ttgacaat 128 <210> 2625 <211> 128 <212> DNA <213> Artificial Sequence <400> 2625 gtattgttgg aaagacgtag acgccactga gctacgcttc tatggttgtg ttgatgggtt 60 acttgctaaa gcgtttattt gtgccatgtt caaccttgat aaacaagcat ttaaccaaac 120 aaacgctc 128 <210> 2626 <211> 128 <212> DNA <213> Artificial Sequence <400> 2626 cctcagtggc gcgctttggt caggatggta ttagtgtgac tggtactcaa tcagagtatg 60 tacaaacaac tagttctgta gaacctacct caggatggag tacaacacgt ccaacacctc 120 aaattggg 128

Claims (36)

  1. 치료용 박테리아를 포함하는 조성물을 분석하기 위한 방법으로서,
    (a) 치료용 박테리아의 성장을 선택적으로 저해하는 조건 하에서 조성물을 배양하는 단계; 및
    (b) 단계 (a)의 배양된 조성물을 분석하여 원치 않는 유기체가 조성물에 존재하는지 여부를 결정하는 단계
    를 포함하는, 방법.
  2. 제1항에 있어서, 상기 단계 (a)의 치료용 박테리아의 성장 저해는 원치 않는 유기체의 성장 저해보다 적어도 2배, 적어도 3배, 적어도 4배, 적어도 5배, 적어도 10배, 적어도 20배, 적어도 50배인, 방법.
  3. 제1항 또는 제2항에 있어서, 단계 (b)가 적어도 하나의 원치 않는 유기체가 미생물 조성물에 존재한다고 결정하는 경우, 상기 방법은 원치 않는 유기체 또는 원치 않는 유기체 각각을 식별하는 단계를 포함하는, 방법.
  4. 제3항에 있어서, 상기 미생물 조성물은 임의의 원치 않는 유기체가 바이러스, 고세균, 진핵 세포 또는 혐기성 또는 호기성 박테리아인지 여부를 결정하기 위해 분석되는, 방법.
  5. 제5항에 있어서, 상기 원치 않는 유기체는 클로스트리디아(Clostridia) 또는 살모넬라(Salmonella) 속 또는 스타필로코커스 아우레우스(Staphylococcus aureus), 슈도모나스 아에루기노사(Pseudomonas aeruginosa) 또는 에쉬리키아 콜라이(Escherichia coli) 종 유래의 박테리아 등, 또는 이러한 원치 않는 유기체의 혼합물인, 방법.
  6. 제1항 내지 제5항 중 어느 한 항에 있어서, 상기 원치 않는 유기체는 세포 유기체이고, 배양하는 단계 이전에 미생물 조성물에서 치료용 박테리아의 세포 수 대 원치 않는 유기체(들)의 세포 수의 비율은 1,000:1 이상, 10,000:1 이상, 100,000:1 이상, 1,000,000:1 이상, 10,000,000:1 이상, 100,000,000:1 이상, 1,000,000,000:1 이상, 10,000,000,000:1 이상인, 방법.
  7. 제1항 내지 제6항 중 어느 한 항에 있어서, 상기 치료용 박테리아의 성장은 배양 배지의 pH, 온도 및/또는 이온 강도를 선택함으로써 선택적으로 저해되는, 방법.
  8. 제1항 내지 제6항 중 어느 한 항에 있어서, 상기 치료용 박테리아의 성장은 치료용 박테리아의 성장을 저해하는 작용제를 배양 배지에 첨가함으로써 선택적으로 저해되는, 방법.
  9. 제8항에 있어서, 상기 작용제는 치료용 박테리아가 증식하는 것을 감소시키거나 방지하는, 방법.
  10. 제8항 또는 제9항에 있어서, 상기 작용제는 조성물에 존재하는 치료용 박테리아를 적어도 90%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.9% 또는 100% 능동적으로 살해하는, 방법.
  11. 제8항 내지 제10항 중 어느 한 항에 있어서, 상기 작용제는 박테리오파지, 라이소자임 또는 항생제인, 방법.
  12. 제11항에 있어서, 상기 작용제는 항생제가 아닌, 방법.
  13. 제11항에 있어서, 상기 작용제는 박테리오파지인, 방법.
  14. 제13항에 있어서, 상기 박테리오파지는 엔테로코커스(Enterococcus) 속의 하나 이상의 박테리아를 선택적으로 저해하는, 방법.
  15. 제13항 또는 제14항에 있어서, 상기 작용제는 서열번호 1을 포함하는 DNA 게놈을 갖는 박테리오파지 또는 이의 기능적 등가물인, 방법.
  16. 제13항 또는 제14항에 있어서, 상기 작용제는 서열번호 2를 포함하는 DNA 게놈을 갖는 박테리오파지 또는 이의 기능적 등가물인, 방법.
  17. 제15항 또는 제16항에 있어서, 상기 기능적 등가물은 서열번호 1 또는 서열번호 2와 적어도 70%, 적어도 80%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 서열 동일성을 갖는 DNA 게놈을 포함하는 박테리오파지인, 방법.
  18. 제16항 또는 제17항에 있어서, 상기 박테리오파지는 NCIMB 43666인, 방법.
  19. 제15항 또는 제17항에 있어서, 상기 박테리오파지는 NCIMB 43667인, 방법.
  20. 제1항 내지 제19항 중 어느 한 항에 있어서, 상기 치료용 박테리아는 혐기성 박테리아, 편성 혐기성 박테리아, 통성 혐기성 박테리아 및/또는 미호기성 박테리아를 포함하거나 이로 이루어지는, 방법.
  21. 제20항에 있어서, 상기 미생물 조성물은 엔테로코커스(예를 들어, 엔테로코커스 갈리나룸(Enterococcus gallinarum), 엔테로코쿠스 카셀리플라버스(Enterococcus caselliflavus), 엔테로코쿠스 페칼리스(Enterococcus faecalis) 또는 엔테로코쿠스 페시움(Enterococcus faecium)), 블라우티아(예를 들어, 블라우티아 하이드로게노트로피카, 블라우티아 스테르코리스(Blautia stercoris), 블라우티아 웩슬러레(Blautia wexlerae) 또는 블라우티아 프로덕타(Blautia producta)), 박테로이데스(예를 들어, 박테로이데스 테타이오타오미크론(Bacteroides thetaiotaomicron), 박테로이데스 마실리엔시스(Bacteroides massiliensis), 박테로이데스 프라질리스(Bacteroides fragilis), 박테로이데스 오바투스(Bacteroides ovatus), 박테로이데스 불가투스(Bacteroides vulgatus), 박테로이데스 도레이(Bacteroides dorei) 또는 박테로이데스 코프리콜라(Bacteroides copricola)), 페칼리박테리움(Faecalibacterium)(예를 들어, 페칼리박테리움 프라우스니치(Faecalibacterium prausnitzii)), 바리아트리쿠스(Bariatricus)(예를 들어, 바리아트리쿠스 마실리엔시스(Bariatricus massiliensis)), 비피도박테리움(예를 들어, 비피도박테리움 브레베(Bifidobacterium breve), 비피도박테리움 아돌레센티스(Bifidobacterium adolescentis) 또는 비피도박테리움 롱검(Bifidobacterium longum)), 로제부리아(Roseburia)(예를 들어, 로제부리아 호미니스(Roseburia hominis), 로제부리아 인테스티날리스(Roseburia intestinalis) 또는 로제부리아 이눌리니보란스(Roseburia inulinivorans)), 플라보니프락토르(Flavonifractor)(예를 들어, 플라보니프락토르 플라우티(Flavonifractor plautii)), 아네로트룬커스(Anaerotruncus)(예를 들어, 아네로트룬커스 콜리호미니스(Anaerotruncus colihominis)), 파라박테로이데스(Parabacteroides)(예를 들어, 파라박테로이데스 디스타소니스(Parabacteroides distasonis), 파라박테로이데스 골드스테이니(Parabacteroides goldsteinii), 파라박테로이데스 메르데(Parabacteroides merdae) 또는 파라박테로이데스 존소니(Parabacteroides johnsonii)), 에리시펠라토클로스트리듐(Erysipelatoclostridium)(예를 들어, 에리시펠라토클로스트리듐 라모섬(Erysipelatoclostridium ramosum)), 메가스페라(Megasphaera)(예를 들어, 메가스페라 마실리엔시스(Megasphaera massiliensis)), 페디오코커스(Pediococcus)(예를 들어, 페디오코커스 악시딜락티시(Pediococcus acidilacticii)), 유박테리움(Eubacterium)(예를 들어, 유박테리움 콘토르텀(Eubacterium contortum), 유박테리움 피시카테나(Eubacterium fissicatena), 유박테리움 엘리젠스(Eubacterium eligens), 유박테리움 하드럼(Eubacterium hadrum), 유박테리움 할리(Eubacterium hallii) 또는 유박테리움 렉타레(Eubacterium rectale)), 루미노코커스(Ruminococcus)(예를 들어, 루미노코커스 토르크(Ruminococcus torques), 루미노코커스 그나버스(Ruminococcus gnavus) 또는 루미노코커스 브로미(Ruminococcus bromii)), 슈도플라보니프락토르(Pseudoflavonifractor)(예를 들어, 슈도플라보니프락토르 카필로서스(Pseudoflavonifractor capillosus)), 클로스트리듐(예를 들어, 클로스트리듐 넥실(Clostridium nexile), 클로스트리듐 힐레모나에(Clostridium hylemonae), 클로스트리듐 부티리쿰(Clostridium butyricum), 클로스트리듐 테르티움(Clostridium tertium), 클로스트리듐 디스포리쿰(Clostridium disporicum), 클로스트리듐 비페르멘탄스(Clostridium bifermentans), 클로스트리듐 이노쿰(Clostridium inocuum), 클로스트리듐 마욤베이(Clostridium mayombei), 클로스트리듐 볼테아에(Clostridium bolteae), 클로스트리듐 바르틀레티(Clostridium bartletti), 클로스트리듐 심비오숨(Clostridium symbiosum) 또는 클로스트리듐 오르비스신덴스(Clostridium orbiscindens)), 코프로코커스(Coprococcus)(예를 들어, 코프로코커스 코메스(Coprococcus comes) 또는 코프로코커스 카투스(Coprococcus cattus)), 아세티비브리오(Acetivibrio)(예를 들어, 아세티비브리오 에타놀기그넨스(Acetovibrio ethanolgignens)), 도레아(Dorea)(예를 들어, 도레아 롱기카테나(Dorea longicatena)) 또는 라크노스피라세(Lachnospiraceae) 과의 임의의 속으로부터의 하나 이상의 박테리아를 포함하는, 방법.
  22. 제4항 또는 이의 임의의 종속항에 있어서, 상기 미생물 조성물 중 원치 않는 유기체의 존재의 결정은 배양된 미생물 조성물 중 세포 산물, 바람직하게는 치료용 박테리아에 의해 생산되지 않고/않거나 클로스트리디아(Clostridia) 및 살모넬라(Salmonella) 속 및 스타필로코커스 아우레우스(Staphylococcus aureus), 슈도모나스 아에루기노사(Pseudomonas aeruginosa) 및 에쉬리키아 콜라이(Escherichia coli) 종으로부터의 유기체와 같은 특정 병원성 박테리아의 존재를 나타내는 세포 산물의 식별을 포함하는, 방법.
  23. 제1항 내지 제21항 중 어느 한 항에 있어서, 단계 (b)는 GC-MS 또는 MALDI-TOF-MS 분석을 포함하는, 방법.
  24. 제1항 내지 제23항 중 어느 한 항에 있어서, 상기 배양하는 단계 a)의 시작 시 미생물 조성물은 1×1012 CFU 이하의 치료용 박테리아를 포함하는, 방법.
  25. 제1항 내지 제23항 중 어느 한 항에 있어서, 상기 배양하는 단계 a)의 시작 시 미생물 조성물은 5×1011 CFU 이하의 치료용 박테리아를 포함하는, 방법.
  26. 제1항 내지 제23항 중 어느 한 항에 있어서, 상기 배양하는 단계 a)의 시작 시 미생물 조성물은 1×1011 CFU 이하의 치료용 박테리아를 포함하는, 방법.
  27. 제1항 내지 제26항 중 어느 한 항에 있어서, 상기 배양하는 단계 a)의 시작 시 미생물 조성물은 하나 이상의 부형제, 예를 들어 동결보호제, 방부제, 항산화제, 안정화제, 프리바이오틱 화합물, 약제학적으로 허용 가능한 담체 또는 희석제, 결합제, 윤활제, 현탁화제, 코팅제, 가용화제 등을 포함하는, 방법.
  28. 제1 박테리아 개체군을 선택적으로 저해하는 작용제 및 제1항 내지 제27항 중 어느 한 항의 방법에서 작용제를 사용하기 위한 지침을 포함하는 키트.
  29. 서열번호 1 또는 서열번호 2를 포함하는 DNA 게놈을 갖는 박테리오파지, 또는 이의 기능적 등가물.
  30. 서열번호 1 또는 서열번호 2와 적어도 70%, 적어도 80%, 적어도 81%, 적어도 82%, 적어도 83%, 적어도 84%, 적어도 85%, 적어도 86%, 적어도 87%, 적어도 88%, 적어도 89%, 적어도 90%, 적어도 91%, 적어도 92%, 적어도 93%, 적어도 94%, 적어도 95%, 적어도 96%, 적어도 97%, 적어도 98%, 적어도 99%, 적어도 99.5%, 적어도 99.7%, 적어도 99.8%, 적어도 99.9% 또는 100% 서열 동일성을 갖는 DNA 게놈을 갖는 박테리오파지.
  31. 하나 이상의 박테리오파지를 포함하되, 미생물 조성물 중 하나 이상의 치료용 박테리아의 성장을 선택적으로 저해하는, 조성물.
  32. 제31항에 있어서, 안정화제, 방부제 및/또는 첨가제를 더 포함하는, 조성물.
  33. 제31항 또는 제32항에 있어서, 상기 조성물은 제28항 또는 제29항에 따른 박테리오파지를 포함하는, 조성물.
  34. 제33항에 있어서, 상기 조성물은 2, 3, 4, 5, 6, 7, 8, 9, 10가지 또는 10가지 초과의 박테리오파지를 포함하는, 조성물.
  35. 제1항 내지 제27항 중 어느 한 항에 있어서, 2가지 이상의 박테리오파지를 포함하되, 미생물 조성물 중 하나 이상의 치료용 박테리아의 성장을 선택적으로 저해하는, 조성물.
  36. 하기 단계들을 포함하는, 약제학적 조성물을 제조하는 방법:
    (a) 치료용 박테리아를 배양하는 단계;
    (b) 단계 (a)의 배양물의 적어도 일 분획에 대해 제1항 내지 제27항 중 어느 한 항의 방법을 수행하는 단계; 및
    (c) 단계 (a)의 치료용 박테리아로부터 약제학적 조성물을 제형화하는 단계.
KR1020237021517A 2020-11-26 2021-11-26 방법 KR20230112700A (ko)

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