CN106165747A - One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea and preparation processing method - Google Patents
One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea and preparation processing method Download PDFInfo
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- CN106165747A CN106165747A CN201610234321.7A CN201610234321A CN106165747A CN 106165747 A CN106165747 A CN 106165747A CN 201610234321 A CN201610234321 A CN 201610234321A CN 106165747 A CN106165747 A CN 106165747A
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- A—HUMAN NECESSITIES
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- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
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- A61K36/076—Poria
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- A61K36/898—Orchidaceae (Orchid family)
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The one that the invention discloses the present invention treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, is made up of the raw material of following weight portion: Radix Codonopsis 5 15 parts, the Rhizoma Atractylodis Macrocephalae 5 15 parts, Cortex Cinnamomi 10 15 parts, 5 12 parts of Poria, Radix Et Rhizoma Rhei 39 parts, Fructus Aurantii 5 12 parts, Cortex Magnoliae Officinalis 5 10 parts, Haematitum 5 10 parts, Fructus Perillae 10 16 parts, 5 15 parts of Radix Glycyrrhizae, Fructus Amomi 6 15 parts, Sword Jackbean Seed 5 10 parts, Concha Arcae 5 10 parts, Pericarpium Citri Reticulatae 5 10 parts, Calyx Kaki 5 10 parts.The invention have the advantage that inventive formulation warming spleen and stomach for dispelling cold, spleen invigorating dissipating fluid-retention, lead relieving accumulation of pathogens clearly, treat deficiency-cold in middle-JIAO food stagnation gastritis, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to one and treat deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, in particular, relate to one and treat middle Jiao
Deficiency and coldness food stagnation gastritis herb tea formula and preparation method thereof technical field.
Background technology
Deficiency-cold in middle-JIAO food stagnation gastritis, because of drinking and eating irregularly, eating cold and uncooked food excessively, or because of cold and cool medicine too, damage spleen is positive, Ming Menhuo
Decline, YANG failing to warm spleen-YANG and show its gastral cavity under one's belt, suspend in mid air, main digesting food, the sun of this gastral cavilty, temperature be can rotten digesting and absorbing the essence of foodstuff it
Essence, fills and supports the whole body, if burnt in cold visitor, then cold in the stomach, cold in the stomach then indigestion, lientery of suffering from abdominal pain, cholera vomiting and diarrhea, the suitable temperature compensation of method for the treatment of
It.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not have warming spleen and stomach for dispelling cold, spleen invigorating dissipating fluid-retention, leads out clearly
Knot, treatment deficiency-cold in middle-JIAO food stagnation gastritis, raising body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall three-hypers, preventing and treating sugar
The sick function with aspects such as giving protection against cancer, anticancer of urine, it is impossible to release the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug
Weight mouthfeel is poor, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, control
The sick beverage simultaneously strengthening body immunity.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease and strengthen the one of the advantages such as body immunity simultaneously and treat deficiency-cold in middle-JIAO food stagnation gastritis medicated tea.
One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, is made up of the raw material of following weight portion: Radix Codonopsis 5-15 part, Rhizoma Atractylodis Macrocephalae 5-
15 parts, Cortex Cinnamomi 10-15 part, Poria 5-12 part, Radix Et Rhizoma Rhei 3-9 part, Fructus Aurantii 5-12 part, Cortex Magnoliae Officinalis 5-10 part, Haematitum 5-10 part, Fructus Perillae
10-16 part, Radix Glycyrrhizae 5-15 part, Fructus Amomi 6-15 part, Sword Jackbean Seed 5-10 part, Concha Arcae 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Calyx Kaki 5-10
Part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
Described a kind of preparation processing method treating deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Codonopsis, Fructus Perillae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merge 2 Radix Codonopsis, Fructus Perillae ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35, system
Radix Codonopsis, Fructus Perillae extract standby；
Sword Jackbean Seed, Concha Arcae, Fructus Amomi, Haematitum mix and blend are put into super micron mill, carries out micronizing and obtain 300-400
Purpose ultra micro mixing fine powders；
Take the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Poria, Radix Et Rhizoma Rhei, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Perillae, Radix Glycyrrhizae, Concha Arcae, Pericarpium Citri Reticulatae, Calyx Kaki, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds and join the party
Ginseng, the extract of Fructus Perillae, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Radix Codonopsis, sweet, flat.Invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough, for weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength,
Lack of appetite, thirsty.
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature;Return spleen, stomach warp;Fragrance matter is soft, can rise and can drop, keep and do not walk to have invigorating the spleen and benefiting QI,
Dampness diuretic, strengthening superficial resistance to stop perspiration.
Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Poria, sweet in the mouth, light, property is put down, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Radix Et Rhizoma Rhei, purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.
Fructus Aurantii, regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery.
Cortex Magnoliae Officinalis, meridian distribution of property and flavor. bitter, pungent, temperature. return spleen, stomach, lung, large intestine channel, warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, expectorant. control chest and abdomen painful abdominal mass
Full distending pain, regurgitation, vomiting, dyspepsia does not disappears, and phlegm retention is breathed heavily.
Haematitum, pancake lung, stomach two through inverse gas cease with preventing or arresting vomiting, Dingchuan, liver-fire drops clearly in lowering the adverse flow of QI, to excessive rising of liver-YANG it
Card and liver-fire move blood.
Fructus Perillae, pungent, temperature.Return lung, large intestine channel, sending down the abnormal ascending QI expectorant, relieving cough and asthma, loosening bowel to relieve constipation.
Radix Glycyrrhizae, and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Benefiting qi and nourishing yin, spleen reinforcing stomach function regulating, Yiqi and vein recovery.
Fructus Amomi, removing dampness appetizing, warming spleen and stopping diarrha, for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels.
Sword Jackbean Seed, sweet, temperature.Return stomach, kidney channel.Warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, the most oh.For deficiency and coldness singultus, vomiting.
Concha Arcae, salty in the mouth, property is put down.Return lung, stomach, Liver Channel.Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Calyx Kaki, bitter, puckery, flat.Return stomach warp.Lowering the adverse QI to relieve hiccough.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, treats deficiency-cold in middle-JIAO food stagnation stomach
Inflammation, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.Each component is screened by great many of experiments
Proportioning, scientific and reasonable；And whole preparation technology is rationally and extract drugs rate efficiency is high, can retain having in raw material well
Effect composition, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, the medium-height grass medical instruments such as the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Poria, Radix Et Rhizoma Rhei, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Perillae, Radix Glycyrrhizae, Concha Arcae, Pericarpium Citri Reticulatae, Calyx Kaki are added
There are warming spleen and stomach for dispelling cold, spleen invigorating dissipating fluid-retention, lead relieving accumulation of pathogens clearly, treat deficiency-cold in middle-JIAO food stagnation gastritis, improve body immunity, defying age, toxin expelling
Skin care, the nourishing function such as taste, resisting fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, is made up of the raw material of following weight portion: Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, meat
12 parts of osmanthus, 10 parts of Poria, Radix Et Rhizoma Rhei 4 parts, Fructus Aurantii 8 parts, Cortex Magnoliae Officinalis 8 parts, Haematitum 8 parts, Fructus Perillae 12 parts, 12 parts of Radix Glycyrrhizae, Fructus Amomi 12 parts,
Sword Jackbean Seed 8 parts, Concha Arcae 8 parts, Pericarpium Citri Reticulatae 8 parts, Calyx Kaki 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are suitable
Amount.
A kind of preparation processing method treating deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Radix Codonopsis, Fructus Perillae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, often
Secondary 2 hours, merge 2 Radix Codonopsis, Fructus Perillae ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35,
Prepare Radix Codonopsis, Fructus Perillae extract standby；
Sword Jackbean Seed, Concha Arcae, Fructus Amomi, Haematitum mix and blend are put into super micron mill, carries out micronizing and obtain 300-400
Purpose ultra micro mixing fine powders；
Take the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Poria, Radix Et Rhizoma Rhei, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Perillae, Radix Glycyrrhizae, Concha Arcae, Pericarpium Citri Reticulatae, Calyx Kaki, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds and join the party
Ginseng, the extract of Fructus Perillae, obtain Matrix Solution III standby；
The hard to bear medicine boiled is pulverized and improves its extract drugs efficiency, make whole formula drug effect farthest be utilized.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., seal through bottle capper and load vial
In, packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, dress
Case, carries and drinks conveniently, and the shelf-life is up to 1-2.
Embodiment 2
One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, is made up of the raw material of following weight portion: Radix Codonopsis 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Cortex Cinnamomi
10 parts, Poria 5 part, watt Radix Et Rhizoma Rhei 3 parts, Fructus Aurantii 5 parts, Cortex Magnoliae Officinalis 5 parts, Haematitum 5 parts, Fructus Perillae 10 parts, 5 parts of Radix Glycyrrhizae, Fructus Amomi 6 parts, cutter
Bean or pea 5 parts, Concha Arcae 5 parts, Pericarpium Citri Reticulatae 5 parts, Calyx Kaki 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
Processing method is with embodiment 1.
Embodiment 3
One treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, is made up of the raw material of following weight portion: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, meat
15 parts of osmanthus, 12 parts of Poria, Radix Et Rhizoma Rhei 9 parts, Fructus Aurantii 12 parts, Cortex Magnoliae Officinalis 10 parts, Haematitum 10 parts, Fructus Perillae 16 parts, 15 parts of Radix Glycyrrhizae, Fructus Amomi 15
Part, Sword Jackbean Seed 10 parts, Concha Arcae 10 parts, Pericarpium Citri Reticulatae 10 parts, Calyx Kaki 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, honeybee
Honey, water are appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 30 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, ante cibum each 500mL
5. index: drink the transference cures such as rear substantially deficiency-cold in middle-JIAO, phlegm retention food stagnation, flatulence pain, inappetence, and mouthfeel is the sourest
Sweet for effective；Drink the remissions such as rear deficiency-cold in middle-JIAO, phlegm retention food stagnation, flatulence pain, inappetence, and mouthfeel is the most sour-sweet, is designated as
Effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Air Bladder pseudosciaenae seu Acipenser can strengthen gastrointestinal digestive and absorptive functions, improves appetite, is conducive to anti-
Control the diseases such as inappetence, anorexia, dyspepsia, abdominal distention, constipation, show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through
Effect, Air Bladder pseudosciaenae seu Acipenser application effect achieves unexpected technique effect.
In sum, the one that the present invention provides treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, warming spleen and stomach for dispelling cold, spleen invigorating dissipating fluid-retention,
Lead clearly relieving accumulation of pathogens, treat deficiency-cold in middle-JIAO food stagnation gastritis, there is sour-sweet mouthfeel, improve body immunity, defying age, eliminating toxin and beautifying the skin,
Nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from medicine-food two-purpose
Natural plants, has no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. a treatment deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, it is characterised in that be made up of the raw material of following weight portion: Radix Codonopsis 5-15
Part, Rhizoma Atractylodis Macrocephalae 5-15 part, Cortex Cinnamomi 10-15 part, Poria 5-12 part, Radix Et Rhizoma Rhei 3-9 part, Fructus Aurantii 5-12 part, Cortex Magnoliae Officinalis 5-10 part, Haematitum 5-
10 parts, Fructus Perillae 10-16 part, Radix Glycyrrhizae 5-15 part, Fructus Amomi 6-15 part, Sword Jackbean Seed 5-10 part, Concha Arcae 5-10 part, Pericarpium Citri Reticulatae 5-10 part,
Calyx Kaki 5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
One the most according to claim 1 treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, it is characterised in that by following weight portion
Raw material make: Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Cortex Cinnamomi 12 parts, 10 parts of Poria, Radix Et Rhizoma Rhei 4 parts, Fructus Aurantii 8 parts, Cortex Magnoliae Officinalis 8 parts, Haematitum
8 parts, Fructus Perillae 12 parts, 12 parts of Radix Glycyrrhizae, Fructus Amomi 12 parts, Sword Jackbean Seed 8 parts, Concha Arcae 8 parts, Pericarpium Citri Reticulatae 8 parts, Calyx Kaki 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new
Fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
One the most according to claim 1 treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, it is characterised in that by following weight portion
Raw material make: Radix Codonopsis 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Cortex Cinnamomi 10 parts, Poria 5 part, watt Radix Et Rhizoma Rhei 3 parts, Fructus Aurantii 5 parts, Cortex Magnoliae Officinalis 5 parts, Haematitum 5
Part, Fructus Perillae 10 parts, 5 parts of Radix Glycyrrhizae, Fructus Amomi 6 parts, Sword Jackbean Seed 5 parts, Concha Arcae 5 parts, Pericarpium Citri Reticulatae 5 parts, Calyx Kaki 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, fresh
Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
One the most according to claim 1 treats deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, it is characterised in that by following weight portion
Raw material make: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Cortex Cinnamomi 15 parts, 12 parts of Poria, Radix Et Rhizoma Rhei 9 parts, Fructus Aurantii 12 parts, Cortex Magnoliae Officinalis 10 parts, Haematitum
10 parts of stone, Fructus Perillae 16 parts, 15 parts of Radix Glycyrrhizae, Fructus Amomi 15 parts, Sword Jackbean Seed 10 parts, Concha Arcae 10 parts, Pericarpium Citri Reticulatae 10 parts, Calyx Kaki 10 parts, fish
Fish glue 10 parts, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water are appropriate.
5. the preparation processing method treating deficiency-cold in middle-JIAO food stagnation gastritis medicated tea, it is characterised in that comprise the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Codonopsis, Fructus Perillae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merge 2 Radix Codonopsis, Fructus Perillae ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35, system
Radix Codonopsis, Fructus Perillae extract standby；
Sword Jackbean Seed, Concha Arcae, Fructus Amomi, Haematitum mix and blend are put into super micron mill, carries out micronizing and obtain 300-400
Purpose ultra micro mixing fine powders；
Take the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Poria, Radix Et Rhizoma Rhei, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Perillae, Radix Glycyrrhizae, Concha Arcae, Pericarpium Citri Reticulatae, Calyx Kaki, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds and join the party
Ginseng, the extract of Fructus Perillae, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
A kind of preparation processing method treating deficiency-cold in middle-JIAO food stagnation gastritis medicated tea the most according to claim 5, its feature exists
In, step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make grapevine knot
Ice, after taking out nature defrosting, then carries out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
A kind of preparation processing method treating deficiency-cold in middle-JIAO food stagnation gastritis medicated tea the most according to claim 5, its feature exists
In, step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae be
10:0.2～0.8:5～10:0.5.
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