CN106173035A - The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein and preparation processing method - Google Patents
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein and preparation processing method Download PDFInfo
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- CN106173035A CN106173035A CN201610234282.0A CN201610234282A CN106173035A CN 106173035 A CN106173035 A CN 106173035A CN 201610234282 A CN201610234282 A CN 201610234282A CN 106173035 A CN106173035 A CN 106173035A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
Abstract
The invention discloses the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, be made up of the raw material of following weight portion: the Radix Astragali 5 15 parts, Ramulus Cinnamomi 5 12 parts, 5 10 parts of Poria, Herba Epimedii 10 16 parts, 5 15 parts of Flos Carthami, Radix Angelicae Sinensis 6 15 parts, Rhizoma Alismatis 5 10 parts, Rhizoma Chuanxiong 5 10 parts, 5 10 parts of Herba Ephedrae, Radix Codonopsis 5 10 parts, Radix Salviae Miltiorrhizae 5 10 parts, Fructus Amomi 5 10 parts, Mytilus 5 10 parts, Fructus Lycii 5 10 parts, Carnis Haliotidis 5 10 parts, the Cortex Eucommiae 5 10 parts.The invention have the advantage that inventive formulation warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, invigorating the spleen for eliminating dampness, inducing diuresis to remove edema, treat urine protein, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, in particular, relate to one
The herb tea formula of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein and preparation method thereof technical field.
Background technology
Under normal circumstances, do not contain protein in human urine or comprise only trace protein, but when kidney generation pathological changes,
When flowing through kidney with the protein of blood circulation flowing, protein is made " to slip through the net " because of the reduction of kidney filtering function.Albumen
Matter leaks into urine and ejects from urethra and define albuminuria.Urine protein the highest explanation kidney filtering function is the poorest, and this is to weigh kidney
The important indicator of dirty function.The traditional Chinese medical science is thought and is answered warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, invigorating the spleen for eliminating dampness, inducing diuresis to remove edema, treats urine protein.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not have warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, spleen invigorating
Wet, inducing diuresis to remove edema, treatment urine protein, raising body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall three-hypers, preventing and treating sugar
The sick function with aspects such as giving protection against cancer, anticancer of urine, it is impossible to release the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug
Weight mouthfeel is poor, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, control
The sick beverage simultaneously strengthening body immunity.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein simultaneously strengthening the advantage such as body immunity.
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, is made up of the raw material of following weight portion: Radix Astragali 5-15
Part, Ramulus Cinnamomi 5-12 part, Poria 5-10 part, Herba Epimedii 10-16 part, Flos Carthami 5-15 part, Radix Angelicae Sinensis 6-15 part, Rhizoma Alismatis 5-10 part, Rhizoma Chuanxiong
5-10 part, Herba Ephedrae 5-10 part, Radix Codonopsis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Fructus Amomi 5-10 part, Mytilus 5-10 part, Fructus Lycii 5-10 part, Bao
Fish 5-10 part, Cortex Eucommiae 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
The preparation processing method of the medicated tea of described a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions
2 times, each 2 hours, merging 2 Rhizoma Chuanxiongs, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into nothing
Alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepare Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae extract standby
With；
Herba Epimedii, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Alismatis being closed stirring and put into super micron mill, super micron mill heating keeps 80 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～8 times
Distilled water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil
With ultra micro mixing fine powders medicinal residues；
Taking the Radix Astragali, Ramulus Cinnamomi, Poria, Fructus Amomi, Mytilus, Fructus Lycii, Carnis Haliotidis, the Cortex Eucommiae, mix homogeneously adds 30-60 DEG C of warm water soaking 10 points
Zhong Hou, puts into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, forms freezing medicine block, by freezing medicine block and ultra micro mixing
Fine powder medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 and divides
Clock；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, temperature
Keep 120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae
Extract and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
The Radix Astragali, returns lung, spleen, liver, kidney channel.Enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and
Wide antibacterial action.
Ramulus Cinnamomi, its nature and flavor acrid, sweet, warm, enter lung, the heart, bladder warp, be to cure mainly the drugs for dispelling internal cold that interior cold is conventional, have complement sun,
Promoting blood circulation, effect of warming the spleen and stomach.
Poria, sweet in the mouth, light, property is put down, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Herba Epimedii, glycosides can increase cardiovascular and cerebrovascular vessel blood flow, promote hemopoietic function, immunologic function and bone metabolism, also have benefit
Kidney and enhancing body, anti-ageing effect of waiting for a long time.
Flos Carthami, pungent, temperature, nontoxic, enter the heart, Liver Channel, stimulate the menstrual flow, invigorate blood circulation.
Radix Angelicae Sinensis, sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.
Rhizoma Alismatis, sweet, light, cold in nature.Return kidney, bladder warp.Promoting diuresis to eliminate damp pathogen, expels the heat-evil, and changes turbid blood fat reducing.
Rhizoma Chuanxiong, acrid in the mouth, temperature, enter liver, spleen, three burnt three warps, activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.
Herba Ephedrae, energy lung qi dispersing gas, loosing the interspaces of skin and muscles, dispersing wind and cold, with relieving the exterior syndrome by diaphoresis, infected by influenza has inhibitory action.Its methanol carries
Take thing and have antiinflammatory action.Its decoct has resisting pathogenic microbes effect.
Radix Codonopsis, sweet, flat.Invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough, for weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength,
Lack of appetite, thirsty.
Radix Salviae Miltiorrhizae, has blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.
Fructus Amomi, removing dampness appetizing, warming spleen and stopping diarrha, for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels.
Mytilus, salty in the mouth, warm in nature, enter spleen, kidney channel;Invigorating the liver and kidney, benefiting essence-blood, help kidney yang, the goiter that disappears, regulating menstruation blood, blood pressure lowering it
Effect.
Fructus Lycii, sweet, flat, for syndrome of yin deficiency of liver and kidney, sweet flat matter is moistened, flat invigorating the liver and kidney, has strengthening by means of tonics effect, and all Liver and kidney are cloudy
Empty all cards all can be applied.
Carnis Haliotidis, has nourishing YIN and invigorating YANG, treating stranguria effect of quenching the thirst, and is a kind of benefit and the driest marine products.
The Cortex Eucommiae, invigorating the liver and kidney, bone and muscle strengthening.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, strong
Spleen removing dampness, inducing diuresis to remove edema, treat urine protein, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resisting fatigue it
Merit.The proportioning of each component is screened by great many of experiments, scientific and reasonable；And whole preparation technology is reasonable and extract drugs rate efficiency
Height, can retain the effective ingredient in raw material well, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add the Chinese herbal medicine such as the Radix Astragali, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Poria and there is warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, invigorating the spleen for eliminating dampness, inducing diuresis to remove edema,
Treatment urine protein, improves the functions such as body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resisting fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, is made up of the raw material of following weight portion: the Radix Astragali 8 parts, Ramulus Cinnamomi 8
Part, 8 parts of Poria, Herba Epimedii 12 parts, 10 parts of Flos Carthami, Radix Angelicae Sinensis 10 parts, Rhizoma Alismatis 8 parts, Rhizoma Chuanxiong 8 parts, 8 parts of Herba Ephedrae, Radix Codonopsis 8 parts, Radix Salviae Miltiorrhizae 8
Part, Fructus Amomi 8 parts, Mytilus 8 parts, Fructus Lycii 8 parts, Carnis Haliotidis 8 parts, the Cortex Eucommiae 8 parts, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are fitted
Amount.
A kind of preparation processing method of the medicated tea of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, described preparation method include with
Lower step；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol
Extracting 2 times, each 2 hours, merge 2 Rhizoma Chuanxiongs, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae ethanol extracts, stand precipitate with ethanol, filter, filtrate concentrates
To without alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepared Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, the extraction of Radix Salviae Miltiorrhizae
Thing is standby；
Herba Epimedii, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Alismatis being closed stirring and put into super micron mill, super micron mill heating keeps 80 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～8 times
Distilled water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil
With ultra micro mixing fine powders medicinal residues；
Taking stilbene, Ramulus Cinnamomi, Poria, Fructus Amomi, Mytilus, Fructus Lycii, Carnis Haliotidis, the Cortex Eucommiae, mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes
After, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, freezing medicine block and ultra micro are mixed carefully
Powder medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 minute；
Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature keeps
120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, the carrying of Radix Salviae Miltiorrhizae
Take thing and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Taking Matrix Solution II through mesh number is
Material-compound tank is put into after the fine filter filter of 100 mesh；Take Matrix Solution III again and put into dispensing after the fine filter filter that mesh number is 60 mesh
In tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5.Sealing through bottle capper loads in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning,
Carrying and drink conveniently, the shelf-life is up to 1-2.
Embodiment 2
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, is made up of the raw material of following weight portion: the Radix Astragali 5 parts, Ramulus Cinnamomi 5
Part, 5 parts of Poria, Herba Epimedii 10 parts, 5 parts of Flos Carthami, Radix Angelicae Sinensis 6 parts, Rhizoma Alismatis 5 parts, Rhizoma Chuanxiong 5 parts, 5 parts of Herba Ephedrae, Radix Codonopsis 5 parts, Radix Salviae Miltiorrhizae 5
Part, Fructus Amomi 5 parts, Mytilus 5-part, Fructus Lycii 5 parts, Carnis Haliotidis 5 parts, the Cortex Eucommiae 5 parts, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are fitted
Amount.Processing method is with embodiment 1.
Embodiment 3
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, is made up of the raw material of following weight portion: the Radix Astragali 15 parts, Ramulus Cinnamomi
12 parts, 10 parts of Poria, Herba Epimedii 16 parts, 15 parts of Flos Carthami, Radix Angelicae Sinensis 15 parts, Rhizoma Alismatis 10 parts, Rhizoma Chuanxiong 10 parts, 10 parts of Herba Ephedrae, Radix Codonopsis 10
Part, Radix Salviae Miltiorrhizae 10 parts, Fructus Amomi 10 parts, Mytilus 10 parts, Fructus Lycii 10 parts, Carnis Haliotidis 10 parts, the Cortex Eucommiae 10 parts, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae
20 parts, Mel, water appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 60 days
3. number is drunk: 50 people
4. drinking method: 600mL for each person every day
5. index: obvious deficiency of spleen-YANG and kidneyYANG, the wet Neiting of water, stagnation of QI-blood, edema of the body, dizziness, lassitude loin and legs, spirit after drinking
The transference cure such as asthenia, inappetence, and mouthfeel is the most sour-sweet for effective；Drink rear deficiency of spleen-YANG and kidneyYANG, the wet Neiting of water, stagnation of QI-blood,
The remissions such as edema of the body, dizziness, lassitude loin and legs, tired mind, inappetence, and mouthfeel is the most sour-sweet, is designated as effectively.Drink
With rear be then designated as without obvious comfort invalid.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser should
Unexpected technique effect is achieved by effect.
In sum, the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein that the present invention provides, warming and recuperating the kidney-YANG, work
Blood blood stasis dispelling, invigorating the spleen for eliminating dampness, inducing diuresis to remove edema, treat urine protein, has sour-sweet mouthfeel, improves body immunity, defying age, toxin expelling
Skin care, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from medicine food
Dual-purpose natural plants, has no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. the medicated tea of a warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, it is characterised in that be made up of the raw material of following weight portion:
Radix Astragali 5-15 part, Ramulus Cinnamomi 5-12 part, Poria 5-10 part, Herba Epimedii 10-16 part, Flos Carthami 5-15 part, Radix Angelicae Sinensis 6-15 part, Rhizoma Alismatis 5-10
Part, Rhizoma Chuanxiong 5-10 part, Herba Ephedrae 5-10 part, Radix Codonopsis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Fructus Amomi 5-10 part, Mytilus 5-10 part, Fructus Lycii 5-
10 parts, Carnis Haliotidis 5-10 part, Cortex Eucommiae 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water appropriate.
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein the most according to claim 1, it is characterised in that by with
The raw material of lower weight portion is made: the Radix Astragali 8 parts, Ramulus Cinnamomi 8 parts, 8 parts of Poria, Herba Epimedii 12 parts, 10 parts of Flos Carthami, Radix Angelicae Sinensis 10 parts, Rhizoma Alismatis 8
Part, Rhizoma Chuanxiong 8 parts, 8 parts of Herba Ephedrae, Radix Codonopsis 8 parts, Radix Salviae Miltiorrhizae 8 parts, Fructus Amomi 8 parts, Mytilus 8 parts, Fructus Lycii 8 parts, Carnis Haliotidis 8 parts, the Cortex Eucommiae 8 parts,
New fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein the most according to claim 1, it is characterised in that by with
The raw material of lower weight portion is made: the Radix Astragali 5 parts, Ramulus Cinnamomi 5 parts, 5 parts of Poria, Herba Epimedii 10 parts, 5 parts of Flos Carthami, Radix Angelicae Sinensis 6 parts, Rhizoma Alismatis 5
Part, Rhizoma Chuanxiong 5 parts, 5 parts of Herba Ephedrae, Radix Codonopsis 5 parts, Radix Salviae Miltiorrhizae 5 parts, Fructus Amomi 5 parts, Mytilus 5-part, Fructus Lycii 5 parts, Carnis Haliotidis 5 parts, the Cortex Eucommiae 5
Part, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
The medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein the most according to claim 1, it is characterised in that by with
The raw material of lower weight portion is made: the Radix Astragali 15 parts, Ramulus Cinnamomi 12 parts, 10 parts of Poria, Herba Epimedii 16 parts, 15 parts of Flos Carthami, Radix Angelicae Sinensis 15 parts, pool
Rush down 10 parts, Rhizoma Chuanxiong 10 parts, 10 parts of Herba Ephedrae, Radix Codonopsis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Fructus Amomi 10 parts, Mytilus 10 parts, Fructus Lycii 10 parts, Carnis Haliotidis
10 parts, the Cortex Eucommiae 10 parts, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.
5. the preparation processing method of the medicated tea of a warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein, it is characterised in that include following
Step；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions
2 times, each 2 hours, merging 2 Rhizoma Chuanxiongs, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into nothing
Alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepare Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae extract standby
With；
Herba Epimedii, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Alismatis being closed stirring and put into super micron mill, super micron mill heating keeps 80 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～8 times
Distilled water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil
With ultra micro mixing fine powders medicinal residues；
Taking the Radix Astragali, Ramulus Cinnamomi, Poria, Fructus Amomi, Mytilus, Fructus Lycii, Carnis Haliotidis, the Cortex Eucommiae, mix homogeneously adds 30-60 DEG C of warm water soaking 10 points
Zhong Hou, puts into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, forms freezing medicine block, by freezing medicine block and ultra micro mixing
Fine powder medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 and divides
Clock；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, temperature
Keep 120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Rhizoma Chuanxiong, Herba Ephedrae, Radix Codonopsis, Radix Salviae Miltiorrhizae
Extract and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
The preparation processing method of the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein the most according to claim 5,
It is characterized in that, step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing method of the medicated tea of a kind of warming and recuperating the kidney-YANG activating blood and resolving stasis and treating urine protein the most according to claim 5,
It is characterized in that, step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight of Oleum Vitis viniferae
Amount proportioning is 10:0.2～0.8:5～10:0.5.
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| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
Non-Patent Citations (2)
| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮等: "《千家妙方上》", 31 July 1982, 战士出版社 * |
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